医学教育学部門

研究成果 1983 2020

フィルター
記事
1993
16 引用 (Scopus)

K channel openers activate different K channels in vascular smooth muscle cells

Kitamura, K. & Kamouchi, M., 8 1 1993, : : Cardiovascular Drugs and Therapy. 7, 3 Supplement, p. 539-546 8 p.

研究成果: ジャーナルへの寄稿記事

Portal Vein
Vascular Smooth Muscle
Smooth Muscle Myocytes
Rabbits
Glyburide
47 引用 (Scopus)

Multiple neutralizing B-cell epitopes of human T-cell leukemia virus type 1 (HTLV-1) identified by human monoclonal antibodies: A basis for the design of an HTLV-1 peptide vaccine

Baba, E., Nakamura, M., Tanaka, Y., Kuroki, M., Itoyama, Y., Nakano, S. & Niho, Y., 1 1 1993, : : Journal of Immunology. 151, 2, p. 1013-1024 12 p.

研究成果: ジャーナルへの寄稿記事

Deltaretrovirus
B-Lymphocyte Epitopes
Subunit Vaccines
Monoclonal Antibodies
Peptides
2 引用 (Scopus)

Synergism between muramyl dipeptide and lipopolysaccharide in the inhibition of glycosaminoglycan synthesis in cultured rat costal chondrocytes

Ikebe, T., Hirata, M., Yanaga, F. & Koga, T., 1 1 1993, : : Annals of the Rheumatic Diseases. 52, 1, p. 32-36 5 p.

研究成果: ジャーナルへの寄稿記事

Acetylmuramyl-Alanyl-Isoglutamine
Chondrocytes
Glycosaminoglycans
Lipopolysaccharides
Rats
3 引用 (Scopus)

The acute toxicity of allyl chloride by subcutaneous injection in mice.

Omura, M., Itonaga, Y., Komatsu, H., Mangen, Z., Hirata, M., Tanaka, A. & Inoue, N., 10 1993, : : Fukuoka igaku zasshi = Hukuoka acta medica. 84, 10, p. 427-432 6 p.

研究成果: ジャーナルへの寄稿記事

Leydig Cells
Subcutaneous Injections
Necrosis
Kidney Tubules
Inbred ICR Mouse
6 引用 (Scopus)

Transfection of interferon-γ gene in a mouse bone marrow stromal preadipocyte cell line causes apoptotic cell death

Nakano, T., Otsuka, T., Ogo, T., Niiro, H., Kuga, S., Zipori, D., Furukawa, Y. & Niho, Y., 12 1 1993, : : Experimental Hematology. 21, 11, p. 1498-1503 6 p.

研究成果: ジャーナルへの寄稿記事

Mesenchymal Stromal Cells
Interferons
Transfection
Cell Death
Cell Line
1992
7 引用 (Scopus)

Activation of cultured bovine aortic endothelial cells by extracellular pyrimidine triphosphate

Kitazono, T., Koichiro, T. & Shigeki, M., 1 1 1992, : : International Journal of Biochemistry. 24, 8, p. 1323-1327 5 p.

研究成果: ジャーナルへの寄稿記事

Endothelial cells
Endothelial Cells
Uridine Triphosphate
Adenosine Triphosphate
Chemical activation

Central effect of μ and δ opioids on neurohormonal and baroreflex regulation in conscious rabbits

Matsumura, K., Abe, I., Tsuchihashi, T., Tominaga, M., Kobayashi, K. & Fujishima, M., 1 1 1992, : : Therapeutic Research. 13, 1, p. 212-217 6 p.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Opioid Analgesics
Rabbits
1 引用 (Scopus)

Comparison of suppression of mutagenicity of benzo(a)pyrene among methylsulfonyl polychlorinated biphenyl isomers

Kiyohara, C., Omura, M., Hirohata, T. & Masuda, Y., 6 1 1992, : : Bulletin of Environmental Contamination and Toxicology. 48, 6, p. 877-883 7 p.

研究成果: ジャーナルへの寄稿記事

mutagenicity
Pyrene
Polychlorinated biphenyls
pyrene
Isomers
16 引用 (Scopus)

Differential modulation by μ- and θ-opioids on baroreceptor reflex in conscious rabbits

Matsumura, K., Abe, I., Tominaga, M., Tsuchihashi, T., Kobayashi, K. & Fujishima, M., 6 1992, : : Hypertension. 19, 6, p. 648-652 5 p.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Opioid Analgesics
Enkephalins
Rabbits
Naloxone
37 引用 (Scopus)

Epstein-Barr virus BCRF1 gene product (viral interleukin 10) inhibits superoxide anion production by human monocytes

Niiro, H., Otsuka, T., Abe, M., Satoh, H., Ogo, T., Nakano, T., Furukawa, Y. & Niho, Y., 1 1 1992, : : Lymphokine and Cytokine Research. 11, 5, p. 209-214 6 p.

研究成果: ジャーナルへの寄稿記事

Viral Proteins
Human Herpesvirus 4
Superoxides
Interleukin-10
Monocytes

In vitro/in vivo effects of 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity of mice.

Kiyohara, C. & Hirohata, T., 10 1992, : : Veterinary and human toxicology. 34, 5, p. 413-416 4 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
unspecific monooxygenase
tetrachlorodibenzo-p-dioxin
Methylcholanthrene
mice
38 引用 (Scopus)

Signal transduction by tumor necrosis factor α is mediated through a guanine nucleotide-binding protein in osteoblast-like cell line, MC3T3-E1

Yanaga, F., Abe, M., Koga, T. & Hirata, M., 1 1 1992, : : Journal of Biological Chemistry. 267, 8, p. 5114-5121 8 p.

研究成果: ジャーナルへの寄稿記事

Signal transduction
Guanine Nucleotides
Osteoblasts
Signal Transduction
Carrier Proteins
54 引用 (Scopus)

Tumor necrosis factor α stimulates sphingomyelinase through the 55 kDa receptor in HL-60 cells

Yanaga, F. & Watson, S. P., 12 21 1992, : : FEBS Letters. 314, 3, p. 297-300 4 p.

研究成果: ジャーナルへの寄稿記事

Sphingomyelin Phosphodiesterase
HL-60 Cells
Sphingomyelins
Hydrolysis
Tumor Necrosis Factor-alpha
1991
4 引用 (Scopus)

Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine

Tsuchihashi, T., Tsukashima, A., Matsumura, K., Abe, I., Tominaga, M., Nakao, Y., Kobayashi, K. & Fujishima, M., 9 1 1991, : : European Journal of Clinical Pharmacology. 41, 3, p. 255-257 3 p.

研究成果: ジャーナルへの寄稿記事

nilvadipine
Ambulatory Blood Pressure Monitoring
Calcium
Blood Pressure
Heart Rate
5 引用 (Scopus)
4-Nitroquinoline-1-oxide
Xeroderma Pigmentosum
Cell Line
Survival
Homozygote
1 引用 (Scopus)

Cellular and subcellular clues to hypertension: Assessment from calcium mobilization data

Kamouchi, M., Akata, T., Xiong, Z., Inoue, R., Kitamura, K. & Kuriyama, H., 12 1 1991, : : Journal of Vascular Medicine and Biology. 3, 4, p. 205-218 14 p.

研究成果: ジャーナルへの寄稿記事

Hypertension
Calcium
49 引用 (Scopus)

Central effect of endothelin on neurohormonal responses in conscious rabbits

Matsumura, K., Abe, I., Tsuchihashi, T., Tominaga, M., Kobayashi, K. & Fujishima, M., 6 1991, : : Hypertension. 17, 6 SUPPL. 2, p. 1192-1196 5 p.

研究成果: ジャーナルへの寄稿記事

Endothelins
Endothelin-1
Rabbits
Kidney
Pentolinium Tartrate
30 引用 (Scopus)

Cromakalim dilates rat cerebral arteries in vitro

Nagao, T., Sadoshima, S., Kamouchi, M. & Fujishima, M., 2 1991, : : Stroke. 22, 2, p. 221-224 4 p.

研究成果: ジャーナルへの寄稿記事

Cromakalim
Cerebral Arteries
Arteries
Perfusion
Pressure
1 引用 (Scopus)

Disseminated intravascular coagulation in a patient with progressive systemic sclerosis associated with necrotizing angiitis and generalized lymphadenopathy

Kamouchi, M., Yoshinari, M., Goto, H., Ishitsuka, T., Murai, K., Tashiroh, K. & Fujishima, M., 1 1 1991, : : Acta Haematologica. 86, 4, p. 203-205 3 p.

研究成果: ジャーナルへの寄稿記事

Diffuse Scleroderma
Disseminated Intravascular Coagulation
Vasculitis
Lymphadenopathy
3 引用 (Scopus)

Distribution of sensitivity to 4-nitroquinoline 1-oxide among Japanese lymphoblastoid cell lines

Kiyohara, C., Hirohata, T., Kuratsune, M. & Nagayama, J., 1 1 1991, : : Bulletin of Environmental Contamination and Toxicology. 46, 1, p. 62-68 7 p.

研究成果: ジャーナルへの寄稿記事

Fluoresceins
4-Nitroquinoline-1-oxide
Fluorescein
Cells

Electrical properties of the voltage-dependent calcium channels in smooth muscle cells

Kitamura, K., Xiong, Z. L. & Kamouchi, M., 5 1991, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 36, 6, p. 869-879 11 p.

研究成果: ジャーナルへの寄稿記事

Electric Conductivity
Endothelins
Second Messenger Systems
Calcium Channels
Muscle Contraction
37 引用 (Scopus)

Evidence for coupling of bradykinin receptors to a guanine-nucleotide binding protein to stimulate arachidonate liberation in the osteoblast-like cell line, MC3T3-E1

Fumi, Y., Masato, H. & Toshitaka, K., 9 3 1991, : : BBA - Molecular Cell Research. 1094, 2, p. 139-146 8 p.

研究成果: ジャーナルへの寄稿記事

Bradykinin Receptors
Guanine Nucleotides
Bradykinin
Osteoblasts
Radioactivity

Interrelationship of cellular fluorescein formation ability, an indication of cell viability, with environmental factors and with aryl hydrocarbon hydroxylase activity

Kiyohara, C., Hirohata, T., Kuratsune, M. & Nagayama, J., 1991, : : Chemosphere. 22, 8, p. 739-746 8 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
Fluorescein
Cell Survival
viability
environmental factor
5 引用 (Scopus)
Aryl Hydrocarbon Hydroxylases
Microsomes
Ascorbic Acid
Liver
Aromatic Hydrocarbons
7 引用 (Scopus)
Bradycardia
Portal Vein
Smooth Muscle Myocytes
Rabbits
Glyburide
3 引用 (Scopus)

Severe Hypertension with Segmental Renal Infarction Following Surgical Removal of a Retroperitoneal Malignant Hemangiopericytoma: A Case Report

Matsumura, K., Muratani, H., Kinjou, K., Kimura, Y., Eto, T., Fukiyama, K. & Kusaba, A., 4 1991, : : Angiology. 42, 4, p. 331-336 6 p.

研究成果: ジャーナルへの寄稿記事

Infarction
Renin-Angiotensin System
Hypertension
Kidney
Angiotensins
4 引用 (Scopus)

Synthetic inositol 1,3,4,5-tetrakisphosphate analogues

Hirata, M., Kimura, Y., Ishimatsu, T., Takahashi, F., Shuto, T., Sasaguri, T., Koga, T., Watanabe, Y. & Ozaki, S., 1 1 1991, : : Biochemical Journal. 276, 2, p. 333-336 4 p.

研究成果: ジャーナルへの寄稿記事

Phosphoric Monoester Hydrolases
Inositol 1,4,5-Trisphosphate
inositol-1,3,4,5-tetrakisphosphate
Erythrocyte Membrane
Hydrolysis
1990
4 引用 (Scopus)

Aryl hydrocarbon hydroxylase activity levels in the hepatic microsomal fraction from MC- or TCDD-treated mice: a comparison between aromatic hydrocarbon responsive and non-responsive strains

Kiyohara, C., Mohri, N., Hirohata, T., Haraguchi, K., Masuda, Y. & Nagayama, J., 6 1990, : : Toxicology Letters. 52, 1, p. 73-80 8 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
Aromatic Hydrocarbons
Liver
Methylcholanthrene
Polycyclic Aromatic Hydrocarbons
11 引用 (Scopus)

Baroreceptor reflex in elderly essential hypertensives: Effect of chronic inhibition of angiotensin converting enzyme

Muratani, H., Kimura, Y., Matsumura, K., Noda, Y., Eto, T. & Fukiyama, K., 1 1 1990, : : Clinical and Experimental Hypertension. A12, 1, p. 97-110 14 p.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Peptidyl-Dipeptidase A
Angiotensin II
Enalapril
Blood Pressure
2 引用 (Scopus)

Catabolic effects of muramyl dipeptide on rabbit chondrocytes

Ikebe, T., Iribe, H., Hirata, M., Yanaga, F. & Koga, T., 1990, : : Arthritis and Rheumatism. 33, 12, p. 1801-1806 6 p.

研究成果: ジャーナルへの寄稿記事

Acetylmuramyl-Alanyl-Isoglutamine
Proteoglycans
Chondrocytes
Glycosaminoglycans
Rabbits
4 引用 (Scopus)
Tumors
Toxicity
gallium oxide
gallium arsenide
gallium phosphide
2 引用 (Scopus)

Comparative toxicologic study of 2,3,4,7,8-pentachlorodibenzofuran in Ah responsive and nonresponsive strains of mice

Nagayama, J., Kiyohara, C., Handa, S. & Horie, A., 1990, : : Chemosphere. 20, 7-9, p. 1165-1172 8 p.

研究成果: ジャーナルへの寄稿記事

comparative study
toxicity
Liver
genotype
Toxicity
6 引用 (Scopus)

Effects of 3-methylsulphonyl-4,5,3′,4′-tetrachlorobiphenyl and 7,8-benzoflavone on mouse liver aryl hydrocarbon hydroxylase activity in vitro

Kiyohara, C., Hirohata, T., Mohri, N. & Masuda, Y., 1990, : : Toxicology in Vitro. 4, 2, p. 103-107 5 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
Liver
Atrial Natriuretic Factor
Methylcholanthrene
Aromatic Hydrocarbons
50 引用 (Scopus)

Effects of glutathione depletion on the acute nephrotoxic potential of arsenite and on arsenic metabolism in hamsters

Hirata, M., Tanaka, A., Hisanaga, A. & Ishinishi, N., 12 1990, : : Toxicology and Applied Pharmacology. 106, 3, p. 469-481 13 p.

研究成果: ジャーナルへの寄稿記事

Buthionine Sulfoximine
Arsenic
Metabolism
Cricetinae
Glutathione
50 引用 (Scopus)

Inositol 1,4,5-trisphosphate affinity chromatography

Hirata, M., Watanabe, Y., Ishimatsu, T., Yanaga, F., Koga, T. & Ozaki, S., 4 16 1990, : : Biochemical and Biophysical Research Communications. 168, 1, p. 379-386 8 p.

研究成果: ジャーナルへの寄稿記事

Affinity chromatography
Inositol 1,4,5-Trisphosphate
Affinity Chromatography
Sepharose
Bioactivity
21 引用 (Scopus)

In Vitro Effects of Methylsulfonyl Polychlorinated Biphenyls and 7,8‐Benzoflavone on Aryl Hydrocarbon Hydroxylase Activity in Human Lymphoblastoid Cells

Kiyohara, C., Mohri, N., Hirohata, T., Haraguchi, K. & Masuda, Y., 4 1990, : : Pharmacology & Toxicology. 66, 4, p. 273-276 4 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Hydroxylases
Polychlorinated Biphenyls
Human Activities
Isomers
Culture Media
1 引用 (Scopus)

Opioids modulate cardiovascular and neurohormonal responses to intracerebroventricular injection of endothelin in conscious rabbits

Matsumura, K., Abe, I., Tsuchihashi, T., Tominaga, M., Kobayashi, K. & Fujishima, M., 12 1 1990, : : Therapeutic Research. 11, 12, p. 105-110 6 p.

研究成果: ジャーナルへの寄稿記事

Endothelins
Opioid Analgesics
Rabbits
Injections
54 引用 (Scopus)

Stereospecific recognition of inositol 1,4,5-trisphosphate analogs by the phosphatase, kinase, and binding proteins

Hirata, M., Yanaga, F., Koga, T., Ogasawara, T., Watanabe, Y. & Ozaki, S., 6 12 1990, : : Journal of Biological Chemistry. 265, 15, p. 8404-8407 4 p.

研究成果: ジャーナルへの寄稿記事

Inositol 1,4,5-Trisphosphate
Phosphoric Monoester Hydrolases
Isomers
Carrier Proteins
Phosphotransferases
1989
6 引用 (Scopus)

Comparative toxicologic study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in Ah responsive and nonresponsive strains of mice

Nagayama, J., Mohri, N., Kiyohara, C., Handa, S. & Horie, A., 1989, : : Chemosphere. 19, 1-6, p. 927-932 6 p.

研究成果: ジャーナルへの寄稿記事

TCDD
dioxin
Toxicity
comparative study
toxicity
22 引用 (Scopus)

Conversion of arsenite and arsenate to methylarsenic and dimethylarsenic compounds by homogenates prepared from livers and kidneys of rats and mice

Hirata, M., Mohri, T., Hisanaga, A. & Ishinishi, N., 1989, : : Applied Organometallic Chemistry. 3, 4, p. 335-341 7 p.

研究成果: ジャーナルへの寄稿記事

Liver
Rats
Arsenic
Methylation
Mercaptoethanol
1 引用 (Scopus)

Effects of 3-methylsulphonyl-4,5,3',4'-tetrachlorobiphenyl and 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity

Nagayama, J., Mohri, N., Haraguschi, K., Masuda, Y., Kiyohara, C. & Hirohata, T., 1 1 1989, : : Fukuoka Acta Medica. 80, 5, p. 201-209 9 p.

研究成果: ジャーナルへの寄稿記事

Benzoflavones
Aryl Hydrocarbon Hydroxylases
Flavones
Polychlorinated Biphenyls
Liver Microsomes

Effects of dioxin congeners on aryl hydrocarbon hydroxylase activity

Nagayama, J., Mohri, N., Masuda, Y., Kiyohara, C. & Hirohata, T., 1 1 1989, : : Fukuoka Acta Medica. 80, 5, p. 196-200 5 p.

研究成果: ジャーナルへの寄稿記事

Drug Dose Response Relationship
Aryl Hydrocarbon Hydroxylases
Dioxins
Cultured Cells
Lymphocytes
8 引用 (Scopus)

Inhibitory effect of methylsulphonyl polychlorinated biphenyls on aryl hydrocarbon hydroxylase activity

Nagayama, J., Kiyohara, C., Mohri, N., Hirohata, T., Haraguchi, K. & Masuda, Y., 1989, : : Chemosphere. 18, 1-6, p. 701-708 8 p.

研究成果: ジャーナルへの寄稿記事

PCB
hydrocarbon
effect
26 引用 (Scopus)

Involvement of calcium and protein kinase C in the activation of the Na+/H+ exchanger in cultured bovine aortic endothelial cells stimulated by extracellular ATP

Kitazono, T., Takeshige, K., Cragoe, E. J. & Minakami, S., 9 19 1989, : : BBA - Molecular Cell Research. 1013, 2, p. 152-158 7 p.

研究成果: ジャーナルへの寄稿記事

Sodium-Hydrogen Antiporter
Protein Kinase C
Endothelial Cells
Adenosine Triphosphate
Calcium
1 引用 (Scopus)

Strain- and organ-dependent differences in induction of aryl hydrocarbon hydroxylase activity by 3-methylcholanthrene

Kiyohara, C., Mohri, N., Nagayama, J. & Hirohata, T., 8 1 1989, : : Bulletin of Environmental Contamination and Toxicology. 43, 2, p. 185-191 7 p.

研究成果: ジャーナルへの寄稿記事

Mice (computer peripherals)
Inbred A Mouse
Aryl Hydrocarbon Hydroxylases
Species Specificity
Inbred CBA Mouse
15 引用 (Scopus)

Two cases of myocardial infarction in type 4 Ehlers-Danlos syndrome

Kitazono, T., Imaizumi, T., Imayama, S., Shinkai, H., Takeshita, A. & Nakamura, M., 1 1 1989, : : Chest. 95, 6, p. 1274-1277 4 p.

研究成果: ジャーナルへの寄稿記事

Ehlers-Danlos Syndrome
Myocardial Infarction
Connective Tissue
Collagen Type III
Aspartate Aminotransferases
19 引用 (Scopus)

Variation of trace metals in ancient and contemporary Japanese bones

Hisanaga, A., Hirata, M., Tanaka, A., Ishinishi, N. & Eguchi, Y., 12 1 1989, : : Biological Trace Element Research. 22, 3, p. 221-231 11 p.

研究成果: ジャーナルへの寄稿記事

Bone
Metals
Bone and Bones
Physiologic Calcification
Ribs
1988
8 引用 (Scopus)

A comparison of the carcinogenicity of N-nitrosodiethylamine and N-nitrosodimethylamine after intratracheal instillation into Syrian golden hamsters

Tanaka, A., Hisanaga, A., Inamasu, T., Hirata, M. & Ishinishi, N., 1988, : : Food and Chemical Toxicology. 26, 10, p. 847-850 4 p.

研究成果: ジャーナルへの寄稿記事

N-nitrosodimethylamine
Dimethylnitrosamine
Diethylnitrosamine
carcinogenicity
Mesocricetus
5 引用 (Scopus)
N-Nitrosopyrrolidine
Propylamines
Dimethylnitrosamine
Diethylnitrosamine
Mesocricetus
5 引用 (Scopus)

Effect of chronic inhibition of angiotensin converting enzyme on baroreceptor reflex in essential hypertension

Muratani, H., Kimura, Y., Matsumura, K., Noda, Y., Eto, T. & Fukiyama, K., 1 1 1988, : : Clinical and Experimental Hypertension. A10, S1, p. 391-398 8 p.

研究成果: ジャーナルへの寄稿記事

Baroreflex
Peptidyl-Dipeptidase A
Angiotensin II
Enalapril
Blood Pressure