細胞機能制御学部門

研究成果 1989 2020

フィルター
記事
78 引用 (Scopus)

PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential

Shia, W. J., Okumura, A. J., Yan, M., Sarkeshik, A., Lo, M. C., Matsuura, S., Komeno, Y., Zhao, X., Nimer, S. D., Yates, J. R. & Zhang, D. E., 5 24 2012, : : Blood. 119, 21, p. 4953-4962 10 p.

研究成果: ジャーナルへの寄稿記事

公開
Protein-Arginine N-Methyltransferases
Transcriptional Activation
Leukemia
Stem Cells
Chemical activation

Production of BBF2H7-derived small peptide fragments via endoplasmic reticulum stress-dependent regulated intramembrane proteolysis

Matsuhisa, K., Saito, A., Cai, L., Kaneko, M., Okamoto, T., Sakaue, F., Asada, R., Urano, F., Yanagida, K., Okochi, M., Kudo, Y., Matsumoto, M., Nakayama, K. I. & Imaizumi, K., 1 1 2020, : : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 1, p. 865-880 16 p.

研究成果: ジャーナルへの寄稿記事

公開
Proteolysis
Peptide Fragments
Endoplasmic Reticulum Stress
Peptide Hydrolases
Basic-Leucine Zipper Transcription Factors
5 引用 (Scopus)

Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors

Takashima, Y., Horisawa, K., Udono, M., Ohkawa, Y. & Suzuki, A., 11 1 2018, : : Cancer Science. 109, 11, p. 3543-3553 11 p.

研究成果: ジャーナルへの寄稿記事

Hepatocellular Carcinoma
Transcription Factor 3
Transcription Factors
Cell Proliferation
Cell Line
43 引用 (Scopus)

Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein

Saita, S., Shirane, M., Natume, T., Iemura, S. I. & Nakayama, K. I., 5 15 2009, : : Journal of Biological Chemistry. 284, 20, p. 13766-13777 12 p.

研究成果: ジャーナルへの寄稿記事

R-SNARE Proteins
Neurites
PC12 Cells
RNA Interference
Rats
4 引用 (Scopus)

Protection of stromal cell-derived factor 2 by heat shock protein 72 prevents oxaliplatin-induced cell death in oxaliplatin-resistant human gastric cancer cells

Takahashi, K., Tanaka, M., Yashiro, M., Matsumoto, M., Ohtsuka, A., Nakayama, K. I., Izumi, Y., Nagayama, K., Miura, K., Iwao, H. & Shiota, M., 8 1 2016, : : Cancer Letters. 378, 1, p. 8-15 8 p.

研究成果: ジャーナルへの寄稿記事

oxaliplatin
HSP72 Heat-Shock Proteins
Stromal Cells
Stomach Neoplasms
Cell Death
31 引用 (Scopus)

Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts

Cremasco, V., Decker, C. E., Stumpo, D., Blackshear, P. J., Nakayama, K., Nakayama, K., Lupu, T. S., Graham, D. B., Novack, D. V. & Faccio, R., 12 1 2012, : : Journal of Bone and Mineral Research. 27, 12, p. 2452-2463 12 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin K
Protein Kinase C-delta
Osteoclasts
Exocytosis
Homeostasis
38 引用 (Scopus)

Protein kinase C δ activates topoisomerase IIα to induce apoptotic cell death in response to DNA damage

Yoshida, K., Yamaguchi, T., Shinagawa, H., Taira, N., Nakayama, K. I. & Miki, Y., 5 1 2006, : : Molecular and cellular biology. 26, 9, p. 3414-3431 18 p.

研究成果: ジャーナルへの寄稿記事

Type II DNA Topoisomerase
Protein Kinase C
DNA Damage
Cell Death
Chromosome Segregation
52 引用 (Scopus)

Protein kinase C-δ and phosphatidylinositol 3-Kinase/Akt activate mammalian target of rapamycin to modulate NF-κB activation and intercellular adhesion molecule-1 (ICAM-1) expression in endothelial cells

Minhajuddin, M., Bijli, K. M., Fazal, F., Sassano, A., Nakayama, K. I., Hay, N., Platanias, L. C. & Rahman, A., 2 13 2009, : : Journal of Biological Chemistry. 284, 7, p. 4052-4061 10 p.

研究成果: ジャーナルへの寄稿記事

Phosphatidylinositol 3-Kinase
Endothelial cells
Sirolimus
Intercellular Adhesion Molecule-1
Protein Kinase C
12 引用 (Scopus)

Protein kinase C-δ phosphorylates Ebp1 and prevents its proteolytic degradation, enhancing cell survival

Liu, Z., Liu, X., Nakayama, K., Nakayama, K. & Ye, K., 3 1 2007, : : Journal of Neurochemistry. 100, 5, p. 1278-1288 11 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Cell Survival
Cells
Phosphorylation
Degradation
52 引用 (Scopus)

Protein kinase Cδ plays a non-redundant role in insulin secretion in pancreatic β cells

Uchida, T., Iwashita, N., Ohara-Imaizumi, M., Ogihara, T., Nagai, S., Choi, J. B., Tamura, Y., Tada, N., Kawamori, R., Nakayama, K. I., Nagamatsu, S. & Watada, H., 1 26 2007, : : Journal of Biological Chemistry. 282, 4, p. 2707-2716 10 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Insulin
Glucose
Protein Isoforms
Phosphorylation
16 引用 (Scopus)

Proteome of ubiquitin/MVB pathway: Possible involvement of iron-induced ubiquitylation of transferrin receptor in lysosomal degradation

Tachiyama, R., Ishikawa, D., Matsumoto, M., Nakayama, K. I., Yoshimori, T., Yokota, S., Himeno, M., Tanaka, Y. & Fujita, H., 4 1 2011, : : Genes to Cells. 16, 4, p. 448-466 19 p.

研究成果: ジャーナルへの寄稿記事

Multivesicular Bodies
Transferrin Receptors
Ubiquitination
Proteome
Ubiquitin
27 引用 (Scopus)

Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin

Oshikawa, K., Matsumoto, M., Oyamada, K. & Nakayama, K. I., 2 3 2012, : : Journal of Proteome Research. 11, 2, p. 796-807 12 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Proteome
Ubiquitin
Lysine
Proteins
126 引用 (Scopus)

Protrudin induces neurite formation by directional membrane trafficking

Shirane, M. & Nakayama, K. I., 11 3 2006, : : Science. 314, 5800, p. 818-821 4 p.

研究成果: ジャーナルへの寄稿記事

Neurites
Guanosine
Membranes
Diphosphates
Extracellular Signal-Regulated MAP Kinases
26 引用 (Scopus)

Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia

Hashimoto, Y., Shirane, M., Matsuzaki, F., Saita, S., Ohnishi, T. & Nakayama, K. I., 1 1 2014, : : Journal of Biological Chemistry. 289, 19, p. 12946-12961 16 p.

研究成果: ジャーナルへの寄稿記事

Hereditary Spastic Paraplegia
Endoplasmic Reticulum
Neurons
Paraplegia
Myelin Proteolipid Protein

Protrudin regulates membrane recycling system

Shirane, M., 12 1 2007, : : Seikagaku. 79, 8, p. 794-796 3 p.

研究成果: ジャーナルへの寄稿記事

Biological Transport
rab GTP-Binding Proteins
Cell Surface Receptors
Nerve Growth Factor
Dendrites
49 引用 (Scopus)
Neurites
Proteins
Neurons
Hereditary Spastic Paraplegia
Membranes
7 引用 (Scopus)

PURE mRNA display for in vitro selection of single-chain antibodies

Nagumo, Y., Fujiwara, K., Horisawa, K., Yanagawa, H. & Doi, N., 5 1 2016, : : Journal of biochemistry. 159, 5, p. 519-526 8 p.

研究成果: ジャーナルへの寄稿記事

Single-Chain Antibodies
Display devices
Messenger RNA
Proteins
In Vitro Techniques
11 引用 (Scopus)

Reconstitution and characterization of the unconventional splicing of XBP1u mRNA in vitro

Shinya, S., Kadokura, H., Imagawa, Y., Inoue, M., Yanagitani, K. & Kohno, K., 7 1 2011, : : Nucleic acids research. 39, 12, p. 5245-5254 10 p.

研究成果: ジャーナルへの寄稿記事

公開
RNA Splicing
Messenger RNA
Cytosol
Endoplasmic Reticulum Stress
Exons

Reconstruction of global regulatory network from signaling to cellular functions using phosphoproteomic data

Kawata, K., Yugi, K., Hatano, A., Kokaji, T., Tomizawa, Y., Fujii, M., Uda, S., Kubota, H., Matsumoto, M., Nakayama, K. I. & Kuroda, S., 1 2019, : : Genes to Cells. 24, 1, p. 82-93 12 p.

研究成果: ジャーナルへの寄稿記事

Insulin
Phosphorylation
Proteins
Protein Kinases
Hepatocellular Carcinoma
39 引用 (Scopus)

Reconstruction of insulin signal flow from phosphoproteome and metabolome data

Yugi, K., Kubota, H., Toyoshima, Y., Noguchi, R., Kawata, K., Komori, Y., Uda, S., Kunida, K., Tomizawa, Y., Funato, Y., Miki, H., Matsumoto, M., Nakayama, K. I., Kashikura, K., Endo, K., Ikeda, K., Soga, T. & Kuroda, S., 8 21 2014, : : Cell Reports. 8, 4, p. 1171-1183 13 p.

研究成果: ジャーナルへの寄稿記事

Metabolome
Phosphorylation
Homeostasis
Liver Type Phosphofructokinase-1
Insulin
54 引用 (Scopus)

Recovery of liver mass without proliferation of hepatocytes after partial hepatectomy in Skp2-deficient mice

Minamishima, Y. A., Nakayama, K. & Nakayama, K., 2002, : : Cancer Research. 62, 4, p. 995-999 5 p.

研究成果: ジャーナルへの寄稿記事

Hepatectomy
Hepatocytes
Polyploidy
Cell Proliferation
Liver
18 引用 (Scopus)

Regulation of APC/C Cdc20 activity by RASSF1A-APC/C Cdc20 circuitry

Chow, C., Wong, N., Pagano, M., Lun, S. W. M., Nakayama, K. I., Nakayama, K. & Lo, K. W., 4 12 2012, : : Oncogene. 31, 15, p. 1975-1987 13 p.

研究成果: ジャーナルへの寄稿記事

Mitosis
Cyclin A
Ubiquitination
Prometaphase
Tumor Suppressor Genes
32 引用 (Scopus)

Regulation of apoptosis and neurite extension by FKBP38 is required for neural tube formation in the mouse

Shirane, M., Ogawa, M., Motoyama, J. & Nakayama, K. I., 6 1 2008, : : Genes to Cells. 13, 6, p. 635-651 17 p.

研究成果: ジャーナルへの寄稿記事

Neural Tube
Neurites
Apoptosis
Embryonic Structures
Sacrococcygeal Region
62 引用 (Scopus)

Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression

Reavie, L., Buckley, S. M., Loizou, E., Takeishi, S., Aranda-Orgilles, B., Ndiaye-Lobry, D., Abdel-Wahab, O., Ibrahim, S., Nakayama, K. I. & Aifantis, I., 3 18 2013, : : Cancer Cell. 23, 3, p. 362-375 14 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia
Ligases
Ubiquitin
12 引用 (Scopus)

Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: Involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of Thr176 in GATA-binding protein 2

Nakajima, T., Kitagawa, K., Ohhata, T., Sakai, S., Uchida, C., Shibata, K., Minegishi, N., Yumimoto, K., Nakayama, K. I., Masumoto, K., Katou, F., Niida, H. & Kitagawa, M., 4 17 2015, : : Journal of Biological Chemistry. 290, 16, p. 10368-10381 14 p.

研究成果: ジャーナルへの寄稿記事

GATA2 Transcription Factor
CDC2 Protein Kinase
Cyclin B
Phosphorylation
Ubiquitin
34 引用 (Scopus)

Regulation of SV40 large T-antigen stability by reversible acetylation

Shimazu, T., Komatsu, Y., Nakayama, K. I., Fukazawa, H., Horinouchi, S. & Yoshida, M., 11 30 2006, : : Oncogene. 25, 56, p. 7391-7400 10 p.

研究成果: ジャーナルへの寄稿記事

Polyomavirus Transforming Antigens
Viral Tumor Antigens
Acetylation
trichostatin A
Lysine
40 引用 (Scopus)

Regulation of the Level of Vesl-1S/Homer-1a Proteins by Ubiquitin-Proteasome Proteolytic Systems

Ageta, H., Kato, A., Hatakeyama, S., Nakayama, K., Isojima, Y. & Sugiyama, H., 5 11 2001, : : Journal of Biological Chemistry. 276, 19, p. 15893-15897 5 p.

研究成果: ジャーナルへの寄稿記事

Proteasome Endopeptidase Complex
Ubiquitin
Proteasome Inhibitors
Proteins
Brain
17 引用 (Scopus)

Renal damage in obstructive nephropathy is decreased in Skp2-deficient mice

Suzuki, S., Fukasawa, H., Kitagawa, K., Uchida, C., Hattori, T., Isobe, T., Oda, T., Misaki, T., Ohashi, N., Nakayama, K., Nakayama, K. I., Hishida, A., Yamamoto, T. & Kitagawa, M., 8 2007, : : American Journal of Pathology. 171, 2, p. 473-483 11 p.

研究成果: ジャーナルへの寄稿記事

Kidney
SKP Cullin F-Box Protein Ligases
Ureteral Obstruction
Cyclin-Dependent Kinase Inhibitor p27
Ubiquitin
6 引用 (Scopus)

Reproductive toxicity of ethylene glycol monoethyl ether in Aldh2 knockout mice

Wang, R. S., Ohtani, K., Suda, M., Kitagawa, K., Nakayama, K., Kawamoto, T. & Nakajima, T., 8 1 2007, : : Industrial health. 45, 4, p. 574-578 5 p.

研究成果: ジャーナルへの寄稿記事

Knockout Mice
ether
ethylene
Toxicity
sperm
343 引用 (Scopus)

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes

Shinkai, Y., Koyasu, S., Nakayama, K. I., Murphy, K. M., Loh, D. Y., Reinherz, E. L. & Alt, F. W., 1 1 1993, : : Science. 259, 5096, p. 822-825 4 p.

研究成果: ジャーナルへの寄稿記事

Transgenes
T-Lymphocytes
Thymocytes
CD3 Antigens
Proteins
1 引用 (Scopus)

Ribophorin ii is involved in the tissue factor expression mediated by phosphatidylserinedependent antiprothrombin antibody on monocytes

Fujieda, Y., Amengual, O., Matsumoto, M., Kuroki, K., Takahashi, H., Kono, M., Kurita, T., Otomo, K., Kato, M., Oku, K., Bohgaki, T., Horita, T., Yasuda, S., Maenaka, K., Hatakeyama, S., Nakayama, K. & Atsumi, T., 6 1 2016, : : Rheumatology (United Kingdom). 55, 6, p. 1117-1126 10 p.

研究成果: ジャーナルへの寄稿記事

Thromboplastin
Prothrombin
Monocytes
Antibodies
Surface Plasmon Resonance
4 引用 (Scopus)

Role of apolipoprotein B100 and oxidized low-density lipoprotein in the monocyte tissue factor induction mediated by anti-β2 glycoprotein i antibodies

Otomo, K., Amengual, O., Fujieda, Y., Nakagawa, H., Kato, M., Oku, K., Horita, T., Yasuda, S., Matsumoto, M., Nakayama, K. I., Hatakeyama, S., Koike, T. & Atsumi, T., 10 1 2016, : : Lupus. 25, 12, p. 1288-1298 11 p.

研究成果: ジャーナルへの寄稿記事

Apolipoproteins
Thromboplastin
Monocytes
Glycoproteins
Antibodies
73 引用 (Scopus)

Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell

Matsuzaki, Y., Nakayama, K. I., Nakayama, K., Tomita, T., Isoda, M., Loh, D. Y. & Nakauchi, H., 2 1 1997, : : Blood. 89, 3, p. 853-862 10 p.

研究成果: ジャーナルへの寄稿記事

Hematopoietic Stem Cells
Stem cells
Lymphocytes
Bone
Bone Marrow
47 引用 (Scopus)

Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cδ

Shin, E. J., Duong, C. X., Nguyen, X. K. T., Li, Z., Bing, G., Bach, J. H., Park, D. H., Nakayama, K., Ali, S. F., Kanthasamy, A. G., Cadet, J. L., Nabeshima, T. & Kim, H. C., 6 15 2012, : : Behavioural Brain Research. 232, 1, p. 98-113 16 p.

研究成果: ジャーナルへの寄稿記事

Methamphetamine
Protein Kinase C
Oxidative Stress
Protein C Inhibitor
Protein Kinase Inhibitors
25 引用 (Scopus)

Role of PRIP-1, a novel Ins(1,4,5)P3 binding protein, in Ins(1,4,5)P3-mediated Ca2+ signaling

Harada, K., Takeuchi, H., Oike, M., Matsuda, M., Kanematsu, T., Yagisawa, H., Nakayama, K. I. I., Maeda, K., Erneux, C. & Hirata, M., 2 1 2005, : : Journal of cellular physiology. 202, 2, p. 422-433 12 p.

研究成果: ジャーナルへの寄稿記事

Carrier Proteins
Inositol
Polyphosphates
Enzyme activity
Phosphoric Monoester Hydrolases
62 引用 (Scopus)

Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation

Kotake, Y., Nakayama, K., Ishida, N. & Nakayama, K., 1 14 2005, : : Journal of Biological Chemistry. 280, 2, p. 1095-1102 8 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Serine
Stabilization
Cell Cycle Resting Phase
Mutation
6 引用 (Scopus)

Role of the ANKMY2-FKBP38 axis in regulation of the sonic hedgehog (Shh) signaling pathway

Saita, S., Shirane, M., Ishitani, T., Shimizu, N. & Nakayama, K. I., 9 12 2014, : : Journal of Biological Chemistry. 289, 37, p. 25639-25654 16 p.

研究成果: ジャーナルへの寄稿記事

Tacrolimus Binding Proteins
Hedgehogs
Fish
Embryonic Structures
Ankyrin Repeat
15 引用 (Scopus)

Role of the Atg9a gene in intrauterine growth and survival of fetal mice

Kojima, T., Yamada, T., Akaishi, R., Furuta, I., Saitoh, T., Nakabayashi, K., Nakayama, K. I., Nakayama, K., Akira, S. & Minakami, H., 9 1 2015, : : Reproductive Biology. 15, 3, p. 131-138 8 p.

研究成果: ジャーナルへの寄稿記事

Fetal Development
mice
Genes
genes
hypertension
108 引用 (Scopus)

Role of the PLC-related, catalytically inactive protein p130 in GABAA receptor function

Kanematsu, T., Jang, I. S., Yamaguchi, T., Nagahama, H., Yoshimura, K., Hidaka, K., Matsuda, M., Takeuchi, H., Misumi, Y., Nakayama, K., Yamamoto, T., Akaike, N., Hirata, M. & Nakayama, K., 3 1 2002, : : EMBO Journal. 21, 5, p. 1004-1011 8 p.

研究成果: ジャーナルへの寄稿記事

GABA-A Receptors
Programmable logic controllers
Proteins
Diazepam
gamma-Aminobutyric Acid
57 引用 (Scopus)

Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle

Hara, T., Kamura, T., Kotoshiba, S., Takahashi, H., Fujiwara, K., Onoyama, I., Shirakawa, M., Mizushima, N. & Nakayama, K. I., 11 1 2005, : : Molecular and cellular biology. 25, 21, p. 9292-9303 12 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
G1 Phase
Ubiquitin
Cell Cycle
Proteins
55 引用 (Scopus)

SCFFbw7 Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction

Fukushima, H., Matsumoto, A., Inuzuka, H., Zhai, B., Lau, A. W., Wan, L., Gao, D., Shaik, S., Yuan, M., Gygi, S. P., Jimi, E., Asara, J. M., Nakayama, K., Nakayama, K. I. & Wei, W., 5 31 2012, : : Cell Reports. 1, 5, p. 434-443 10 p.

研究成果: ジャーナルへの寄稿記事

T-cells
Ubiquitination
T-Lymphocytes
Ubiquitin-Protein Ligases
Cell death
374 引用 (Scopus)

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

Inuzuka, H., Shaik, S., Onoyama, I., Gao, D., Tseng, A., Maser, R. S., Zhai, B., Wan, L., Gutierrez, A., Lau, A. W., Xiao, Y., Christie, A. L., Aster, J., Settleman, J., Gygi, S. P., Kung, A. L., Look, T., Nakayama, K. I., Depinho, R. A. & Wei, W., 3 3 2011, : : Nature. 471, 7336, p. 104-109 6 p.

研究成果: ジャーナルへの寄稿記事

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Ubiquitination
Apoptosis
Colonic Neoplasms
Neoplasms

SCFFbxw7 ubiquitylates KLF7 for degradation in a manner dependent on GSK-3-mediated phosphorylation

Sugiyama, S., Yumimoto, K., Inoue, I. & Nakayama, K. I., 5 2019, : : Genes to Cells. 24, 5, p. 354-365 12 p.

研究成果: ジャーナルへの寄稿記事

Glycogen Synthase Kinase 3
Ligases
Ubiquitin
Phosphorylation
Maintenance
23 引用 (Scopus)

SCFβTrCP1 activates and ubiquitylates TAp63γ

Gallegos, J. R., Litersky, J., Lee, H., Sun, Y., Nakayama, K., Nakayama, K. & Lu, H., 1 4 2008, : : Journal of Biological Chemistry. 283, 1, p. 66-75 10 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin-Protein Ligases
Ubiquitination
Protein Isoforms
Up-Regulation
Stabilization
58 引用 (Scopus)

Selective escape of proteins from the mitochondria during mitophagy

Saita, S., Shirane, M. & Nakayama, K. I., 10 28 2013, : : Nature communications. 4, 1410.

研究成果: ジャーナルへの寄稿記事

Mitochondrial Degradation
Mitochondria
mitochondria
endoplasmic reticulum
escape
3 引用 (Scopus)

Sez6l2 regulates phosphorylation of ADD and neuritogenesis

Yaguchi, H., Yabe, I., Takahashi, H., Watanabe, M., Nomura, T., Kano, T., Matsumoto, M., Nakayama, K. I., Watanabe, M. & Hatakeyama, S., 12 9 2017, : : Biochemical and Biophysical Research Communications. 494, 1-2, p. 234-241 8 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Seizures
Glutamate Receptors
Cerebellar Ataxia
Signal transduction
404 引用 (Scopus)

SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

Ikeda, F., Deribe, Y. L., Skånland, S. S., Stieglitz, B., Grabbe, C., Franz-Wachtel, M., Van Wijk, S. J. L., Goswami, P., Nagy, V., Terzic, J., Tokunaga, F., Androulidaki, A., Nakagawa, T., Pasparakis, M., Iwai, K., Sundberg, J. P., Schaefer, L., Rittinger, K., MacEk, B. & Dikic, I., 3 31 2011, : : Nature. 471, 7340, p. 637-641 5 p.

研究成果: ジャーナルへの寄稿記事

Ligases
Ubiquitin
Apoptosis
Caspase 8
Ubiquitination
78 引用 (Scopus)

Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis

Kumari, S., Redouane, Y., Lopez-Mosqueda, J., Shiraishi, R., Romanowska, M., Lutzmayer, S., Kuiper, J., Martinez, C., Dikic, I., Pasparakis, M. & Ikeda, F., 1 1 2014, : : eLife. 3

研究成果: ジャーナルへの寄稿記事

公開
Tumor Necrosis Factor Receptors
Fas-Associated Death Domain Protein
Keratinocytes
Skin
Apoptosis
37 引用 (Scopus)
Cullin Proteins
Ligases
Ubiquitin
Stem Cells
Spermatogonia
69 引用 (Scopus)

Skp2 controls adipocyte proliferation during the development of obesity

Sakai, T., Sakaue, H., Nakamura, T., Okada, M., Matsuki, Y., Watanabe, E., Hiramatsu, R., Nakayama, K., Nakayama, K. & Kasuga, M., 1 19 2007, : : Journal of Biological Chemistry. 282, 3, p. 2038-2046 9 p.

研究成果: ジャーナルへの寄稿記事

Adipocytes
Obesity
Tissue
Nutrition
Ablation