細胞機能制御学部門

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Cell cycle-dependent expression of mammalian E2-C regulated by the anaphase-promoting complex/cyclosome

Yamanaka, A., Hatakeyama, S., Kominami, K. I., Kitagawa, M., Matsumoto, M. & Nakayama, K. I., 1 1 2000, : : Molecular biology of the cell. 11, 8, p. 2821-2831 11 p.

研究成果: ジャーナルへの寄稿記事

44 引用 (Scopus)

Cell Aggregation Culture Induces Functional Differentiation of Induced Hepatocyte-like Cells through Activation of Hippo Signaling

Yamamoto, J., Udono, M., Miura, S., Sekiya, S. & Suzuki, A., 10 2 2018, : : Cell Reports. 25, 1, p. 183-198 16 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P

Mitra, P., Ghule, P. N., Van Der Deen, M., Medina, R., Xie, R. L., Holmes, W. F., Ye, X., Nakayama, K., Harper, J. W., Stein, J. L., Stein, G. S. & Van Wijnen, A. J., 5 1 2009, : : Journal of cellular physiology. 219, 2, p. 438-448 11 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

CDK inhibitors, p21Cip1 and p27Kip1, participate in cell cycle exit of mammalian cardiomyocytes

Tane, S., Ikenishi, A., Okayama, H., Iwamoto, N., Nakayama, K. I. & Takeuchi, T., 1 17 2014, : : Biochemical and Biophysical Research Communications. 443, 3, p. 1105-1109 5 p.

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

Cathepsin E prevents tumor growth and metastasis by catalyzing the proteolytic release of soluble TRAIL from tumor cell surface

Kawakubo, T., Okamoto, K., Iwata, J. I., Shin, M., Okamoto, Y., Yasukochi, A., Nakayama, K. I., Kadowaki, T., Tsukuba, T. & Yamamoto, K., 11 15 2007, : : Cancer Research. 67, 22, p. 10869-10878 10 p.

研究成果: ジャーナルへの寄稿記事

65 引用 (Scopus)

Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors

Tsukuba, T., Yamamoto, S., Yanagawa, M., Okamoto, K., Okamoto, Y., Nakayama, K. I., Kadowaki, T. & Yamamoto, K., 7 1 2006, : : Journal of biochemistry. 140, 1, p. 57-66 10 p.

研究成果: ジャーナルへの寄稿記事

40 引用 (Scopus)

Cathepsin E deficiency induces a novel form of lysosomal storage disorder showing the accumulation of lysosomal membrane sialoglycoproteins and the elevation of lysosomal pH in macrophages

Yanagawa, M., Tsukuba, T., Nishioku, T., Okamoto, Y., Okamoto, K., Takii, R., Terada, Y., Nakayama, K. I., Kadowaki, T. & Yamamoto, K., 1 19 2007, : : Journal of Biological Chemistry. 282, 3, p. 1851-1862 12 p.

研究成果: ジャーナルへの寄稿記事

45 引用 (Scopus)

Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase

Tamamori-Adachi, M., Takagi, H., Hashimoto, K., Goto, K., Hidaka, T., Koshimizu, U., Yamada, K., Goto, I., Maejima, Y., Isobe, M., Nakayama, K. I., Inomata, N. & Kitajima, S., 11 1 2008, : : Cardiovascular research. 80, 2, p. 181-190 10 p.

研究成果: ジャーナルへの寄稿記事

27 引用 (Scopus)

Blue light-induced autophosphorylation of phototropin is a primary step for signaling

Inoue, S. I., Kinoshita, T., Matsumoto, M., Nakayama, K. I., Doi, M. & Shimazaki, K. I., 4 8 2008, : : Proceedings of the National Academy of Sciences of the United States of America. 105, 14, p. 5626-5631 6 p.

研究成果: ジャーナルへの寄稿記事

157 引用 (Scopus)

Bcl-xL is a negative regulator of caspase-3 activation in immature neurons during development

Urase, K., Momoi, T., Fujita, E., Isahara, K., Uchiyama, Y., Tokunaga, A., Nakayama, K. I. & Motoyama, N., 8 5 1999, : : Developmental Brain Research. 116, 1, p. 69-78 10 p.

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

He, C. H., Waxman, A. B., Lee, C. G., Link, H., Rabach, M. E., Ma, B., Chen, Q., Zhu, Z., Zhong, M., Nakayama, K., Nakayama, K. I., Homer, R. & Elias, J. A., 4 2005, : : Journal of Clinical Investigation. 115, 4, p. 1039-1048 10 p.

研究成果: ジャーナルへの寄稿記事

70 引用 (Scopus)

Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16

Hosokawa, H., Romero-Wolf, M., Yui, M. A., Ungerbäck, J., Quiloan, M. L. G., Matsumoto, M., Nakayama, K. I., Tanaka, T. & Rothenberg, E. V., 12 1 2018, : : Nature Immunology. 19, 12, p. 1427-1440 14 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

A strategy for large-scale phosphoproteomics and SRM-based validation of human breast cancer tissue samples

Narumi, R., Murakami, T., Kuga, T., Adachi, J., Shiromizu, T., Muraoka, S., Kume, H., Kodera, Y., Matsumoto, M., Nakayama, K., Miyamoto, Y., Ishitobi, M., Inaji, H., Kato, K. & Tomonaga, T., 11 2 2012, : : Journal of Proteome Research. 11, 11, p. 5311-5322 12 p.

研究成果: ジャーナルへの寄稿記事

67 引用 (Scopus)

Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia

Shibata, H., Joo, A., Fujii, Y., Tani, A., Makino, C., Hirata, N., Kikuta, R., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 10 30 2001, : : Psychiatric Genetics. 11, 3, p. 139-144 6 p.

研究成果: ジャーナルへの寄稿記事

30 引用 (Scopus)

Association of cathepsin E deficiency with the increased territorial aggressive response of mice

Shigematsu, N., Fukuda, T., Yamamoto, T., Nishioku, T., Yamaguchi, T., Himeno, M., Nakayama, K. I., Tsukuba, T., Kadowaki, T., Okamoto, K., Higuchi, S. & Yamamoto, K., 5 1 2008, : : Journal of Neurochemistry. 105, 4, p. 1394-1404 11 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Association of Cathepsin E Deficiency with Development of Atopic Dermatitis

Tsukuba, T., Okamoto, K., Okamoto, Y., Yanagawa, M., Kohmura, K., Yasuda, Y., Uchi, H., Nakahara, T., Furue, M., Nakayama, K., Kadowaki, T., Yamamoto, K. & Nakayama, K. I., 12 1 2003, : : Journal of biochemistry. 134, 6, p. 893-902 10 p.

研究成果: ジャーナルへの寄稿記事

65 引用 (Scopus)

A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer

Kodama, M., Oshikawa, K., Shimizu, H., Yoshioka, S., Takahashi, M., Izumi, Y., Bamba, T., Tateishi, C., Tomonaga, T., Matsumoto, M. & Nakayama, K. I., 12 1 2020, : : Nature communications. 11, 1, 1320.

研究成果: ジャーナルへの寄稿記事

公開

ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway

Ohtsuka, T., Ryu, H., Minamishima, Y. A., Macip, S., Sagara, J., Nakayama, K. I., Aaronson, S. A. & Lee, S. W., 2 1 2004, : : Nature Cell Biology. 6, 2, p. 121-128 8 p.

研究成果: ジャーナルへの寄稿記事

176 引用 (Scopus)

Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-δ knockout mice

Shukla, A., Lounsbury, K. M., Barrett, T. F., Gell, J., Rincon, M., Butnor, K. J., Taatjes, D. J., Davis, G. S., Vacek, P., Nakayama, K. I., Nakayama, K., Steele, C. & Mossman, B. T., 1 2007, : : American Journal of Pathology. 170, 1, p. 140-151 12 p.

研究成果: ジャーナルへの寄稿記事

37 引用 (Scopus)

Artificial intelligence in oncology

Shimizu, H. & Nakayama, K. I., 1 1 2020, (受理済み/印刷中) : : Cancer Science.

研究成果: ジャーナルへの寄稿記事

公開

Aplidin™ induces the mitochondrial apoptotic pathway via oxidative stress-mediated JNK and p38 activation and protein kinase C δ

García-Fernández, L. F., Losada, A., Alcaide, V., Álvarez, A. M., Cuadrado, A., González, L., Nakayama, K., Nakayama, K., Fernández-Sousa, J. M., Muñoz, A. & Sánchez-Puelles, J. M., 1 1 2002, : : Oncogene. 21, 49, p. 7533-7544 12 p.

研究成果: ジャーナルへの寄稿記事

114 引用 (Scopus)

A novel route for connexin 43 to inhibit cell proliferation: Negative regulation of S-phase kinase-associated protein (Skp 2)

Zhang, Y. W., Nakayama, K., Nakayama, K. & Morita, I., 4 1 2003, : : Cancer Research. 63, 7, p. 1623-1630 8 p.

研究成果: ジャーナルへの寄稿記事

110 引用 (Scopus)

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin

Kitagawa, M., Hatakeyama, S., Shirane, M., Matsumoto, M., Ishida, N., Hattori, K., Nakamichi, I., Kikuchi, A., Nakayama, K. I. & Nakayama, K., 5 4 1999, : : EMBO Journal. 18, 9, p. 2401-2410 10 p.

研究成果: ジャーナルへの寄稿記事

446 引用 (Scopus)

An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation

Chen, Z., Foster, M. W., Zhang, J., Mao, L., Rockman, H. A., Kawamoto, T., Kitagawa, K., Nakayama, K., Hess, D. T. & Stamler, J. S., 8 23 2005, : : Proceedings of the National Academy of Sciences of the United States of America. 102, 34, p. 12159-12164 6 p.

研究成果: ジャーナルへの寄稿記事

175 引用 (Scopus)

Anchoring of the 26S proteasome to the organellar membrane by FKBP38

Nakagawa, T., Shirane, M., Lemura, S. I., Natsume, T. & Nakayama, K., 6 1 2007, : : Genes to Cells. 12, 6, p. 709-719 11 p.

研究成果: ジャーナルへの寄稿記事

40 引用 (Scopus)

An animal model manifesting neurodegeneration and obesity

Susaki, E. & Nakayama, K. I., 7 2010, : : Aging. 2, 7, p. 453-456 4 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Alteration of intra-pancreatic target-organ specificity by abrogation of Aire in NOD mice

Niki, S., Oshikawa, K., Mouri, Y., Hirota, F., Matsushima, A., Yano, M., Han, H., Bando, Y., Izumi, K., Matsumoto, M., Nakayama, K. I., Kuroda, N. & Matsumoto, M., 5 1 2006, : : Journal of Clinical Investigation. 116, 5, p. 1292-1301 10 p.

研究成果: ジャーナルへの寄稿記事

79 引用 (Scopus)

Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis

Hoshi, H., Hao, W., Fujita, Y., Funayama, A., Miyauchi, Y., Hashimoto, K., Miyamoto, K., Iwasaki, R., Sato, Y., Kobayashi, T., Miyamoto, H., Yoshida, S., Mori, T., Kanagawa, H., Katsuyama, E., Fujie, A., Kitagawa, K., Nakayama, K. I., Kawamoto, T., Sano, M. および8人, Fukuda, K., Ohsawa, I., Ohta, S., Morioka, H., Matsumoto, M., Chiba, K., Toyama, Y. & Miyamoto, T., 9 1 2012, : : Journal of Bone and Mineral Research. 27, 9, p. 2015-2023 9 p.

研究成果: ジャーナルへの寄稿記事

29 引用 (Scopus)

Aldehyde dehydrogenase 2 knockout accentuates ethanol-induced cardiac depression: Role of protein phosphatases

Ma, H., Yu, L., Byra, E. A., Hu, N., Kitagawa, K., Nakayama, K. I., Kawamoto, T. & Ren, J., 8 1 2010, : : Journal of Molecular and Cellular Cardiology. 49, 2, p. 322-329 8 p.

研究成果: ジャーナルへの寄稿記事

55 引用 (Scopus)

Aldehyde dehydrogenase (ALDH) 2 associates with oxidation of methoxyacetaldehyde; in vitro analysis with liver subcellular fraction derived from human and Aldh2 gene targeting mouse

Kitagawa, K., Kawamoto, T., Kunugita, N., Tsukiyama, T., Okamoto, K., Yoshida, A., Nakayama, K. & Nakayama, K. I., 7 7 2000, : : FEBS Letters. 476, 3, p. 306-311 6 p.

研究成果: ジャーナルへの寄稿記事

106 引用 (Scopus)

A large-scale targeted proteomics assay resource based on an in vitro human proteome

Matsumoto, M., Matsuzaki, F., Oshikawa, K., Goshima, N., Mori, M., Kawamura, Y., Ogawa, K., Fukuda, E., Nakatsumi, H., Natsume, T., Fukui, K., Horimoto, K., Nagashima, T., Funayama, R., Nakayama, K. & Nakayama, K. I., 2 28 2017, : : Nature Methods. 14, 3, p. 251-258 8 p.

研究成果: ジャーナルへの寄稿記事

32 引用 (Scopus)

Akt1-mediated Gata3 phosphorylation controls the repression of IFNÎ 3 in memory-type Th2 cells

Hosokawa, H., Tanaka, T., Endo, Y., Kato, M., Shinoda, K., Suzuki, A., Motohashi, S., Matsumoto, M., Nakayama, K. I. & Nakayama, T., 4 7 2016, : : Nature communications. 7, 11289.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

AIRE Functions as an E3 Ubiquitin Ligase

Uchida, D., Hatakeyama, S., Matsushima, A., Han, H., Ishido, S., Hotta, H., Kudoh, J., Shimizu, N., Doucas, V., Nakayama, K. I., Kuroda, N. & Matsumoto, M., 1 19 2004, : : Journal of Experimental Medicine. 199, 2, p. 167-172 6 p.

研究成果: ジャーナルへの寄稿記事

120 引用 (Scopus)

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

Miranda-Carboni, G. A., Krum, S. A., Yee, K., Nava, M., Deng, Q. E., Pervin, S., Collado-Hidalgo, A., Galić, Z., Zack, J. A., Nakayama, K., Nakayama, K. I. & Lane, T. F., 11 15 2008, : : Genes and Development. 22, 22, p. 3121-3134 14 p.

研究成果: ジャーナルへの寄稿記事

59 引用 (Scopus)

A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen

Oshikawa, K., Matsumoto, M., Kodama, M., Shimizu, H. & Nakayama, K. I., 3 5 2020, : : Oncogene. 39, 10, p. 2170-2186 17 p.

研究成果: ジャーナルへの寄稿記事

Activation of cyclin-dependent kinase 2 (Cdk2) in growth-stimulated rat astrocytes: Geranylgeranylated Rho small GTPase(s) are essential for the induction of cyclin E gene expression

Tanaka, T., Tatsuno, I., Noguchi, Y., Uchida, D., Oeda, T., Narumiya, S., Yasuda, T., Higashi, H., Kitagawa, M., Nakayama, K., Saito, Y. & Hirai, A., 10 9 1998, : : Journal of Biological Chemistry. 273, 41, p. 26772-26778 7 p.

研究成果: ジャーナルへの寄稿記事

35 引用 (Scopus)
公開
2 引用 (Scopus)

Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial reactive oxygen species emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle

Wakabayashi, Y., Tamura, Y., Kouzaki, K., Kikuchi, N., Hiranuma, K., Menuki, K., Tajima, T., Yamanaka, Y., Sakai, A., Nakayama, K. I., Kawamoto, T., Kitagawa, K. & Nakazato, K., 4 1 2020, : : American journal of physiology. Regulatory, integrative and comparative physiology. 318, 4, p. R677-R690

研究成果: ジャーナルへの寄稿記事

Acetaldehyde administrationinduces salsolinol formation in vivo in the dorsal striatum of Aldh2-knockout and C57BL/6N mice

Ito, A., Jamal, M., Ameno, K., Tanaka, N., Takakura, A., Kawamoto, T., Kitagawa, K., Nakayama, K., Matsumoto, A., Miki, T. & Kinoshita, H., 10 15 2018, : : Neuroscience Letters. 685, p. 50-54 5 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene

Hamasaki, A., Sendo, F., Nakayama, K., Ishida, N., Negishi, I., Nakayama, K. I. & Hatakeyama, S., 12 7 1998, : : Journal of Experimental Medicine. 188, 11, p. 1985-1992 8 p.

研究成果: ジャーナルへの寄稿記事

178 引用 (Scopus)

Absence of SKP2 expression attenuates BCR-ABL-induced myeloproliferative disease

Agarwal, A., Bumm, T. G. P., Corbin, A. S., O'Hare, T., Loriaux, M., Van Dyke, J., Willis, S. G., Deininger, J., Nakayama, K. I., Druker, B. J. & Deininger, M. W., 9 1 2008, : : Blood. 112, 5, p. 1960-1970 11 p.

研究成果: ジャーナルへの寄稿記事

49 引用 (Scopus)

Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice

Furuyama, T., Kitayama, K., Shimoda, Y., Ogawa, M., Sone, K., Yoshida-Araki, K., Hisatsune, H., Nishikawa, S. I., Nakayama, K., Nakayama, K., Ikeda, K., Motoyama, N. & Mori, N., 8 13 2004, : : Journal of Biological Chemistry. 279, 33, p. 34741-34749 9 p.

研究成果: ジャーナルへの寄稿記事

244 引用 (Scopus)

Ablation of p27 enhance kainate-induced seizure and hippocampal degeneration

Ueyama, C., Akashiba, H., Nakayama, K., Nakayama, K., Nishiyama, N. & Matsuki, N., 11 2007, : : NeuroReport. 18, 17, p. 1781-1785 5 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Ablation of Fbxw7 Eliminates Leukemia-Initiating Cells by Preventing Quiescence

Takeishi, S., Matsumoto, A., Onoyama, I., Naka, K., Hirao, A. & Nakayama, K. I., 3 18 2013, : : Cancer Cell. 23, 3, p. 347-361 15 p.

研究成果: ジャーナルへの寄稿記事

97 引用 (Scopus)

Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice

Takai, H., Tominaga, K., Motoyama, N., Minamishima, Y. A., Nagahama, H., Tsukiyama, T., Ikeda, K., Nakayama, K., Nakanishi, M. & Nakayama, K., 6 15 2000, : : Genes and Development. 14, 12, p. 1439-1447 9 p.

研究成果: ジャーナルへの寄稿記事

411 引用 (Scopus)

A 23 gene–based molecular prognostic score precisely predicts overall survival of breast cancer patients

Shimizu, H. & Nakayama, K. I., 8 2019, : : EBioMedicine. 46, p. 150-159 10 p.

研究成果: ジャーナルへの寄稿記事

公開
3 引用 (Scopus)