細胞機能制御学部門

研究成果 1989 2020

フィルター
記事
2014
36 引用 (Scopus)
Cullin Proteins
Ligases
Ubiquitin
Stem Cells
Spermatogonia
25 引用 (Scopus)

Skp2 suppresses apoptosis in Rb1-deficient tumours by limiting E2F1 activity

Lu, Z., Bauzon, F., Fu, H., Cui, J., Zhao, H., Nakayama, K., Nakayama, K. & Zhu, L., 3 17 2014, : : Nature communications. 5, 3463.

研究成果: ジャーナルへの寄稿記事

Cyclin A
deletion
apoptosis
Tumors
Carcinogenesis
6 引用 (Scopus)

Tyk2-dependent bystander activation of conventional and nonconventional Th1 cell subsets contributes to innate host defense against listeria monocytogenes infection

Hashiguchi, T., Oyamada, A., Sakuraba, K., Shimoda, K., Nakayama, K. I., Iwamoto, Y., Yoshikai, Y. & Yamada, H., 5 15 2014, : : Journal of Immunology. 192, 10, p. 4739-4747 9 p.

研究成果: ジャーナルへの寄稿記事

TYK2 Kinase
Listeriosis
Th1 Cells
Listeria monocytogenes
Interleukin-12
23 引用 (Scopus)

ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway

Adachi, S., Homoto, M., Tanaka, R., Hioki, Y., Murakami, H., Suga, H., Matsumoto, M., Nakayama, K. I., Hatta, T., Iemura, S. I. & Natsume, T., 1 1 2014, : : Nucleic acids research. 42, 15, p. 10037-10049 13 p.

研究成果: ジャーナルへの寄稿記事

LDL Receptors
RNA Stability
Phosphotransferases
Messenger RNA
Antisense Oligonucleotides
2013
85 引用 (Scopus)

Ablation of Fbxw7 Eliminates Leukemia-Initiating Cells by Preventing Quiescence

Takeishi, S., Matsumoto, A., Onoyama, I., Naka, K., Hirao, A. & Nakayama, K., 3 18 2013, : : Cancer Cell. 23, 3, p. 347-361 15 p.

研究成果: ジャーナルへの寄稿記事

Leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Hematopoietic Stem Cells
Stem Cells
Maintenance
16 引用 (Scopus)
Chondrogenesis
Osteogenesis
Endoplasmic Reticulum
SKP Cullin F-Box Protein Ligases
F-Box Proteins
120 引用 (Scopus)

FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes

Hirano, A., Yumimoto, K., Tsunematsu, R., Matsumoto, M., Oyama, M., Kozuka-Hata, H., Nakagawa, T., Lanjakornsiripan, D., Nakayama, K. I. & Fukada, Y., 2 28 2013, : : Cell. 152, 5, p. 1106-1118 13 p.

研究成果: ジャーナルへの寄稿記事

Cryptochromes
Circadian Clocks
Ubiquitination
Clocks
Stabilization
2 引用 (Scopus)

Hereditary spastic paraplegia protein spartin is an FK506-binding protein identified by mRNA display

Tokunaga, M., Shiheido, H., Hayakawa, I., Utsumi, A., Takashima, H., Doi, N., Horisawa, K., Sakuma-Yonemura, Y., Tabata, N. & Yanagawa, H., 7 25 2013, : : Chemistry and Biology. 20, 7, p. 935-942 8 p.

研究成果: ジャーナルへの寄稿記事

Hereditary Spastic Paraplegia
Tacrolimus Binding Proteins
Tacrolimus
Display devices
Messenger RNA
12 引用 (Scopus)

Loss of Protein Kinase C-δ Protects against LPS-Induced Osteolysis Owing to an Intrinsic Defect in Osteoclastic Bone Resorption

Khor, E. C., Abel, T., Tickner, J., Chim, S. M., Wang, C., Cheng, T., Ng, B., Ng, P. Y., Teguh, D. A., Kenny, J., Yang, X., Chen, H., Nakayama, K. I., Nakayama, K., Pavlos, N., Zheng, M. H. & Xu, J., 8 8 2013, : : PloS one. 8, 8, e70815.

研究成果: ジャーナルへの寄稿記事

Osteolysis
bone resorption
protein kinase C
Bone Resorption
Protein Kinase C
16 引用 (Scopus)

Opposing functions of Fbxw7 in keratinocyte growth, differentiation and skin tumorigenesis mediated through negative regulation of c-Myc and Notch

Ishikawa, Y., Hosogane, M., Okuyama, R., Aoyama, S., Onoyama, I., Nakayama, K. I. & Nakayama, K., 4 11 2013, : : Oncogene. 32, 15, p. 1921-1932 12 p.

研究成果: ジャーナルへの寄稿記事

Keratinocytes
Carcinogenesis
Skin
Growth
SKP Cullin F-Box Protein Ligases
65 引用 (Scopus)

P57 controls adult neural stem cell quiescence and modulates the pace of lifelong neurogenesis

Furutachi, S., Matsumoto, A., Nakayama, K. I. & Gotoh, Y., 4 3 2013, : : EMBO Journal. 32, 7, p. 970-981 12 p.

研究成果: ジャーナルへの寄稿記事

Adult Stem Cells
Neural Stem Cells
Neurogenesis
Stem cells
Cyclin-Dependent Kinase Inhibitor p57
20 引用 (Scopus)

Phosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1

Yamamoto, A., Takeya, R., Matsumoto, M., Nakayama, K. & Sumimoto, H., 10 1 2013, : : FEBS Journal. 280, 20, p. 5145-5159 15 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Threonine
Superoxides
Acetates
Protein Kinase C
60 引用 (Scopus)

Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression

Reavie, L., Buckley, S. M., Loizou, E., Takeishi, S., Aranda-Orgilles, B., Ndiaye-Lobry, D., Abdel-Wahab, O., Ibrahim, S., Nakayama, K. & Aifantis, I., 3 18 2013, : : Cancer Cell. 23, 3, p. 362-375 14 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia
Ligases
Ubiquitin
57 引用 (Scopus)

Selective escape of proteins from the mitochondria during mitophagy

Saita, S., Shirane, M. & Nakayama, K. I., 10 28 2013, : : Nature communications. 4, 1410.

研究成果: ジャーナルへの寄稿記事

Mitochondrial Degradation
Mitochondria
mitochondria
endoplasmic reticulum
escape
40 引用 (Scopus)

Skp2 Deletion Unmasks a p27 Safeguard that Blocks Tumorigenesis in the Absence of pRb and p53 Tumor Suppressors

Zhao, H., Bauzon, F., Fu, H., Lu, Z., Cui, J., Nakayama, K., Nakayama, K., Locker, J. & Zhu, L., 11 11 2013, : : Cancer Cell. 24, 5, p. 645-659 15 p.

研究成果: ジャーナルへの寄稿記事

Ligases
Ubiquitin
Carcinogenesis
Neoplasms
Bromodeoxyuridine
13 引用 (Scopus)

Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF Fbxl3) protein complex

Yumimoto, K., Muneoka, T., Tsuboi, T. & Nakayama, K. I., 11 8 2013, : : Journal of Biological Chemistry. 288, 45, p. 32766-32776 11 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Substrates
Proteins
Cryptochromes
Circadian Clocks
23 引用 (Scopus)

Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles

Hikichi, T., Matoba, R., Ikeda, T., Watanabe, A., Yamamoto, T., Yoshitake, S., Tamura-Nakano, M., Kimura, T., Kamon, M., Shimura, M., Kawakami, K., Okuda, A., Okochi, H., Inoue, T., Suzuki, A. & Masui, S., 4 16 2013, : : Proceedings of the National Academy of Sciences of the United States of America. 110, 16, p. 6412-6417 6 p.

研究成果: ジャーナルへの寄稿記事

Cell Dedifferentiation
Transcription Factors
Hepatocytes
Maintenance
Cell Line
24 引用 (Scopus)

Zoledronic Acid Enhances Lipopolysaccharide-Stimulated Proinflammatory Reactions through Controlled Expression of SOCS1 in Macrophages

Muratsu, D., Yoshiga, D., Taketomi, T., Onimura, T., Seki, Y., Matsumoto, A. & Nakamura, S., 7 9 2013, : : PloS one. 8, 7, e67906.

研究成果: ジャーナルへの寄稿記事

zoledronic acid
Bisphosphonate-Associated Osteonecrosis of the Jaw
Macrophages
Diphosphonates
jaws
2012
26 引用 (Scopus)

Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis

Hoshi, H., Hao, W., Fujita, Y., Funayama, A., Miyauchi, Y., Hashimoto, K., Miyamoto, K., Iwasaki, R., Sato, Y., Kobayashi, T., Miyamoto, H., Yoshida, S., Mori, T., Kanagawa, H., Katsuyama, E., Fujie, A., Kitagawa, K., Nakayama, K. I., Kawamoto, T., Sano, M. および8人, Fukuda, K., Ohsawa, I., Ohta, S., Morioka, H., Matsumoto, M., Chiba, K., Toyama, Y. & Miyamoto, T., 9 1 2012, : : Journal of Bone and Mineral Research. 27, 9, p. 2015-2023 9 p.

研究成果: ジャーナルへの寄稿記事

Acetaldehyde
Aldehydes
Osteoporosis
Mutation
Aldehyde Dehydrogenase
66 引用 (Scopus)

A strategy for large-scale phosphoproteomics and SRM-based validation of human breast cancer tissue samples

Narumi, R., Murakami, T., Kuga, T., Adachi, J., Shiromizu, T., Muraoka, S., Kume, H., Kodera, Y., Matsumoto, M., Nakayama, K., Miyamoto, Y., Ishitobi, M., Inaji, H., Kato, K. & Tomonaga, T., 11 2 2012, : : Journal of Proteome Research. 11, 11, p. 5311-5322 12 p.

研究成果: ジャーナルへの寄稿記事

Phosphopeptides
Biomarkers
Phosphorylation
Tissue
Breast Neoplasms
24 引用 (Scopus)

Comprehensive identification of substrates for f-box proteins by differential proteomics analysis

Yumimoto, K., Matsumoto, M., Oyamada, K., Moroishi, T. & Nakayama, K. I., 6 1 2012, : : Journal of Proteome Research. 11, 6, p. 3175-3185 11 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Ligases
Ubiquitin
Proteomics
Substrates
27 引用 (Scopus)

Copy number loss of FBXW7 is related to gene expression and poor prognosis in esophageal squamous cell carcinoma

Yokobori, T., Mimori, K., Iwatsuki, M., Ishii, H., Tanaka, F., Sato, T., Toh, H., Sudo, T., Iwaya, T., Tanaka, Y., Onoyama, I., Kuwano, H., Nakayama, K. I. & Mori, M., 7 1 2012, : : International journal of oncology. 41, 1, p. 253-259 7 p.

研究成果: ジャーナルへの寄稿記事

Gene Expression
Proportional Hazards Models
Small Interfering RNA
Esophageal Neoplasms
Tumor Suppressor Genes
24 引用 (Scopus)

Corneal antifibrotic switch identified in genetic and pharmacological deficiency of vimentin

Bargagna-Mohan, P., Paranthan, R. R., Hamza, A., Zhan, C. G., Lee, D. M., Kim, K. B., Lau, D. L., Srinivasan, C., Nakayama, K., Nakayama, K., Herrmann, H. & Mohan, R., 1 6 2012, : : Journal of Biological Chemistry. 287, 2, p. 989-1006 18 p.

研究成果: ジャーナルへの寄稿記事

Vimentin
Switches
Pharmacology
Desmin
Intermediate Filaments
8 引用 (Scopus)

Development of mice without Cip/Kip CDK inhibitors

Tateishi, Y., Matsumoto, A., Kanie, T., Hara, E., Nakayama, K. & Nakayama, K. I., 10 19 2012, : : Biochemical and Biophysical Research Communications. 427, 2, p. 285-292 8 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinases
Fibroblasts
Cyclin D1
Cells
Cell Cycle
3 引用 (Scopus)

DNA display selection of peptide ligands for a full-length human G protein-coupled receptor on CHO-K1 cells

Doi, N., Yamakawa, N., Matsumoto, H., Yamamoto, Y., Nagano, T., Matsumura, N., Horisawa, K. & Yanagawa, H., 1 10 2012, : : PloS one. 7, 1, e30084.

研究成果: ジャーナルへの寄稿記事

Chinese hamsters
G-Protein-Coupled Receptors
Cricetulus
Peptide Library
angiotensin II
48 引用 (Scopus)

Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer

Grim, J. E., Knoblaugh, S. E., Guthrie, K. A., Hagar, A., Swanger, J., Hespelt, J., Delrow, J. J., Small, T., Grady, W. M., Nakayama, K. I. & Clurman, B. E., 6 1 2012, : : Molecular and cellular biology. 32, 11, p. 2160-2167 8 p.

研究成果: ジャーナルへの寄稿記事

Intestinal Neoplasms
Colorectal Neoplasms
Chromosomal Instability
Adenocarcinoma
Ubiquitin
35 引用 (Scopus)

Genetic reevaluation of the Role of F-Box proteins in cyclin D1 degradation

Kanie, T., Onoyama, I., Matsumoto, A., Yamada, M., Nakatsumi, H., Tateishi, Y., Yamamura, S., Tsunematsu, R., Matsumoto, M. & Nakayama, K. I., 2 1 2012, : : Molecular and cellular biology. 32, 3, p. 590-605 16 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Cyclin D1
Fibroblasts
Half-Life
Ubiquitination
62 引用 (Scopus)

Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway

Nishiyama, M., Skoultchi, A. I. & Nakayama, K. I., 1 1 2012, : : Molecular and cellular biology. 32, 2, p. 501-512 12 p.

研究成果: ジャーナルへの寄稿記事

Catenins
Wnt Signaling Pathway
Histones
DNA-Binding Proteins
Transcriptional Activation
12 引用 (Scopus)

Identification of CHD7 S as a novel splicing variant of CHD7 with functions similar and antagonistic to those of the full-length CHD7 L

Kita, Y., Nishiyama, M. & Nakayama, K., 7 1 2012, : : Genes to Cells. 17, 7, p. 536-547 12 p.

研究成果: ジャーナルへの寄稿記事

CHARGE Syndrome
DNA Helicases
Chromatin Assembly and Disassembly
Alternative Splicing
RNA Interference
4 引用 (Scopus)

Increased efficiency in the generation of induced pluripotent stem cells by Fbxw7 ablation

Okita, Y., Matsumoto, A., Yumimoto, K., Isoshita, R. & Nakayama, K. I., 9 1 2012, : : Genes to Cells. 17, 9, p. 768-777 10 p.

研究成果: ジャーナルへの寄稿記事

Induced Pluripotent Stem Cells
Embryonic Stem Cells
Fibroblasts
F-Box Proteins
Ligases
179 引用 (Scopus)

Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes

Sekiya, S. & Suzuki, A., 11 1 2012, : : Journal of Clinical Investigation. 122, 11, p. 3914-3918 5 p.

研究成果: ジャーナルへの寄稿記事

Cholangiocarcinoma
Hepatocytes
Neoplasms
Hepatitis
Liver

New horizons in biological research developed by nextgeneration proteomics: Say good-bye to western blotting

Nakatsumi, H., Matsumoto, M. & Nakayama, K., 12 1 2012, : : Seikagaku. 84, 1, p. 53-57 5 p.

研究成果: ジャーナルへの寄稿記事

Mass spectrometry
Peptides
Proteomics

PRMT1 interacts with AML1-ETO to promote its transcriptional activation and progenitor cell proliferative potential

Shia, W. J., Okumura, A. J., Yan, M., Sarkeshik, A., Lo, M. C., Matsuura, S., Komeno, Y., Zhao, X., Nimer, S. D., Yates, J. R. & Zhang, D. E., 5 24 2012, : : Blood. 119, 21, p. 4953-4962 10 p.

研究成果: ジャーナルへの寄稿記事

公開
Protein-Arginine N-Methyltransferases
Transcriptional Activation
Leukemia
Stem Cells
Chemical activation
31 引用 (Scopus)

Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts

Cremasco, V., Decker, C. E., Stumpo, D., Blackshear, P. J., Nakayama, K., Nakayama, K., Lupu, T. S., Graham, D. B., Novack, D. V. & Faccio, R., 12 1 2012, : : Journal of Bone and Mineral Research. 27, 12, p. 2452-2463 12 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin K
Protein Kinase C-delta
Osteoclasts
Exocytosis
Homeostasis
27 引用 (Scopus)

Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin

Oshikawa, K., Matsumoto, M., Oyamada, K. & Nakayama, K. I., 2 3 2012, : : Journal of Proteome Research. 11, 2, p. 796-807 12 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Proteome
Ubiquitin
Lysine
Proteins
17 引用 (Scopus)

Regulation of APC/C Cdc20 activity by RASSF1A-APC/C Cdc20 circuitry

Chow, C., Wong, N., Pagano, M., Lun, S. W. M., Nakayama, K. I., Nakayama, K. & Lo, K. W., 4 12 2012, : : Oncogene. 31, 15, p. 1975-1987 13 p.

研究成果: ジャーナルへの寄稿記事

Mitosis
Cyclin A
Ubiquitination
Prometaphase
Tumor Suppressor Genes
47 引用 (Scopus)

Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase Cδ

Shin, E. J., Duong, C. X., Nguyen, X. K. T., Li, Z., Bing, G., Bach, J. H., Park, D. H., Nakayama, K., Ali, S. F., Kanthasamy, A. G., Cadet, J. L., Nabeshima, T. & Kim, H. C., 6 15 2012, : : Behavioural Brain Research. 232, 1, p. 98-113 16 p.

研究成果: ジャーナルへの寄稿記事

Methamphetamine
Protein Kinase C
Oxidative Stress
Protein C Inhibitor
Protein Kinase Inhibitors
53 引用 (Scopus)

SCFFbw7 Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction

Fukushima, H., Matsumoto, A., Inuzuka, H., Zhai, B., Lau, A. W., Wan, L., Gao, D., Shaik, S., Yuan, M., Gygi, S. P., Jimi, E., Asara, J. M., Nakayama, K., Nakayama, K. I. & Wei, W., 5 31 2012, : : Cell Reports. 1, 5, p. 434-443 10 p.

研究成果: ジャーナルへの寄稿記事

T-cells
Ubiquitination
T-Lymphocytes
Ubiquitin-Protein Ligases
Cell death
12 引用 (Scopus)

The amelioration of renal damage in Skp2-deficient mice canceled by p27Kip1 deficiency in Skp2-/- p27-/- mice

Suzuki, S., Fukasawa, H., Misaki, T., Togawa, A., Ohashi, N., Kitagawa, K., Kotake, Y., Liu, N., Niida, H., Nakayama, K., Nakayama, K. I., Yamamoto, T. & Kitagawa, M., 4 27 2012, : : PloS one. 7, 4, e36249.

研究成果: ジャーナルへの寄稿記事

Ureteral Obstruction
kidneys
Kidney
Cyclin A
Cyclin E
26 引用 (Scopus)

The pathophysiologic role of the protein kinase Cδ pathway in the intervertebral discs of rabbits and mice: In vitro, ex vivo, and in vivo studies

Ellman, M. B., Kim, J. S., An, H. S., Kroin, J. S., Li, X., Chen, D., Yan, D., Buechter, D. D., Nakayama, K., Liu, B., Morgan, S. & Im, H. J., 6 1 2012, : : Arthritis and rheumatism. 64, 6, p. 1950-1959 10 p.

研究成果: ジャーナルへの寄稿記事

Intervertebral Disc
Protein Kinase C
Rabbits
Intervertebral Disc Degeneration
Knockout Mice
193 引用 (Scopus)

The Skp2-SCF E3 ligase regulates akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

Chan, C. H., Li, C. F., Yang, W. L., Gao, Y., Lee, S. W., Feng, Z., Huang, H. Y., Tsai, K. K. C., Flores, L. G., Shao, Y., Hazle, J. D., Yu, D., Wei, W., Sarbassov, D., Hung, M. C., Nakayama, K. I. & Lin, H. K., 5 25 2012, : : Cell. 149, 5, p. 1098-1111 14 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin-Protein Ligases
Ubiquitination
Glycolysis
TNF Receptor-Associated Factor 6
Carcinogenesis
2011
21 引用 (Scopus)

Deficiency of Rap1-Binding Protein RAPL Causes Lymphoproliferative Disorders through Mislocalization of p27kip1

Katagiri, K., Ueda, Y., Tomiyama, T., Yasuda, K., Toda, Y., Ikehara, S., Nakayama, K. & Kinashi, T., 1 28 2011, : : Immunity. 34, 1, p. 24-38 15 p.

研究成果: ジャーナルへの寄稿記事

Lymphoproliferative Disorders
Carrier Proteins
Lymphocytes
B-Cell Lymphoma
S Phase Cell Cycle Checkpoints
14 引用 (Scopus)

Deficient p27 phosphorylation at serine 10 increases macrophage foam cell formation and aggravates atherosclerosis through a proliferation-independent mechanism

Fuster, J. J., González-Navarro, H., Vinué, A., Molina-Sànchez, P., Andrés-Manzano, M. J., Nakayama, K. I., Nakayama, K., Díez-Juan, A., Bernad, A., Rodríguez, C., Martínez-González, J. & Andrés, V., 11 1 2011, : : Arteriosclerosis, thrombosis, and vascular biology. 31, 11, p. 2455-2463 9 p.

研究成果: ジャーナルへの寄稿記事

Foam Cells
Serine
Atherosclerosis
Macrophages
Phosphorylation
11 引用 (Scopus)

Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice

Matsumoto, A., Susaki, E., Onoyama, I., Nakayama, K., Hoshino, M. & Nakayama, K. I., 10 1 2011, : : Molecular and cellular biology. 31, 20, p. 4176-4192 17 p.

研究成果: ジャーナルへの寄稿記事

Hydrocephalus
Interneurons
Subcommissural Organ
Cell Cycle Checkpoints
Cyclin-Dependent Kinase Inhibitor p57
521 引用 (Scopus)

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

Sekiya, S. & Suzuki, A., 7 21 2011, : : Nature. 475, 7356, p. 390-395 6 p.

研究成果: ジャーナルへの寄稿記事

Hepatocytes
Fibroblasts
Tissue Transplantation
Liver
Liver Transplantation
26 引用 (Scopus)

Ex vivo maintenance of hematopoietic stem cells by quiescence induction through Fbxw7α overexpression

Iriuchishima, H., Takubo, K., Matsuoka, S., Onoyama, I., Nakayama, K. I., Nojima, Y. & Suda, T., 2 24 2011, : : Blood. 117, 8, p. 2373-2377 5 p.

研究成果: ジャーナルへの寄稿記事

Hematopoietic Stem Cells
Stem cells
Maintenance
Cell Cycle
Cells
60 引用 (Scopus)

Fbxw7-dependent degradation of notch is required for control of "Stemness" and neuronal-glial differentiation in neural stem cells

Matsumoto, A., Onoyama, I., Sunabori, T., Kageyama, R., Okano, H. & Nakayama, K. I., 4 15 2011, : : Journal of Biological Chemistry. 286, 15, p. 13754-13764 11 p.

研究成果: ジャーナルへの寄稿記事

Neural Stem Cells
Stem cells
Neuroglia
Brain
Degradation
72 引用 (Scopus)

Fbxw7 regulates lipid metabolism and cell fate decisions in the mouse liver

Onoyama, I., Suzuki, A., Matsumoto, A., Tomita, K., Katagiri, H., Oike, Y., Nakayama, K. & Nakayama, K. I., 1 4 2011, : : Journal of Clinical Investigation. 121, 1, p. 342-354 13 p.

研究成果: ジャーナルへの寄稿記事

Lipid Metabolism
F-Box Proteins
Liver
Biliary Tract
S-Phase Kinase-Associated Proteins
16 引用 (Scopus)

Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress

Matsumoto, A., Tateishi, Y., Onoyama, I., Okita, Y., Nakayama, K. & Nakayama, K., 4 1 2011, : : Cancer Science. 102, 4, p. 749-755 7 p.

研究成果: ジャーナルへの寄稿記事

Endoplasmic Reticulum
Oxidative Stress
Cell Membrane
Protein Isoforms
F-Box Proteins
10 引用 (Scopus)

Four mood stabilizers commonly induce FEZ1 expression in human astrocytes

Yu, Z., Ono, C., Kim, H. B., Komatsu, H., Tanabe, Y., Sakae, N., Nakayama, K., Matsuoka, H., Sora, I., Bunney, W. E. & Tomita, H., 8 1 2011, : : Bipolar Disorders. 13, 5-6, p. 486-499 14 p.

研究成果: ジャーナルへの寄稿記事

Fasciculation
Astrocytes
Proteins
Genes
Neurons