細胞機能制御学部門

研究成果 1989 2019

フィルター
記事
2006
39 引用 (Scopus)

Cathepsin E-deficient mice show increased susceptibility to bacterial infection associated with the decreased expression of multiple cell surface Toll-like receptors

Tsukuba, T., Yamamoto, S., Yanagawa, M., Okamoto, K., Okamoto, Y., Nakayama, K., Kadowaki, T. & Yamamoto, K., 7 1 2006, : : Journal of biochemistry. 140, 1, p. 57-66 10 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin E
Toll-Like Receptors
Bacterial Infections
Cells
Macrophages
41 引用 (Scopus)

Degradation of Tob1 mediated by SCFSkp2-dependent ubiquitination

Hiramatsu, Y., Kitagawa, K., Suzuki, T., Uchida, C., Hattori, T., Kikuchi, H., Oda, T., Hatakeyama, S., Nakayama, K. I., Yamamoto, T., Konno, H. & Kitagawa, M., 9 1 2006, : : Cancer Research. 66, 17, p. 8477-8483 7 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Ubiquitin
F-Box Proteins
Cyclin D1
Ligases
4 引用 (Scopus)

Expression of cdc2 and p27(KIP1) phosphorylation in mitotic cells of the human retinoblastoma

Kase, S., Yoshida, K., Ohgami, K., Shiratori, K., Suzuki, Y., Nakayama, K. I. & Ohno, S., 3 1 2006, : : International journal of molecular medicine. 17, 3, p. 465-468 4 p.

研究成果: ジャーナルへの寄稿記事

Retinoblastoma
Phosphorylation
Prophase
Anaphase
Metaphase
33 引用 (Scopus)
Cell Cycle
Protein Isoforms
Cells
Messenger RNA
Fibroblasts
51 引用 (Scopus)

Fbxw7 contributes to tumor suppression by targeting multiple proteins for ubiquitin-dependent degradation

Fujii, Y., Yada, M., Nishiyama, M., Kamura, T., Takahashi, H., Tsunematsu, R., Susaki, E., Nakagawa, T., Matsumoto, A. & Nakayama, K. I., 8 1 2006, : : Cancer Science. 97, 8, p. 729-736 8 p.

研究成果: ジャーナルへの寄稿記事

Cyclin E
Protein Transport
Ubiquitin
F-Box Proteins
Neoplasms
35 引用 (Scopus)

Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development

Tsunematsu, R., Nishiyama, M., Kotoshiba, S., Saiga, T., Kamura, T. & Nakayama, K. I., 8 1 2006, : : Molecular and cellular biology. 26, 16, p. 6157-6169 13 p.

研究成果: ジャーナルへの寄稿記事

Placentation
Embryonic Structures
Cullin Proteins
F-Box Proteins
Fetal Growth Retardation
49 引用 (Scopus)

Geminin is essential for the development of preimplantation mouse embryos

Hara, K., Nakayama, K. & Nakayama, K., 11 1 2006, : : Genes to Cells. 11, 11, p. 1281-1293 13 p.

研究成果: ジャーナルへの寄稿記事

Geminin
Embryonic Development
DNA Replication
Blastomeres
Embryonic Structures
89 引用 (Scopus)

HSP27 favors ubiquitination and proteasomal degradation of p27 Kip1 and helps S-phase re-entry in stressed cells

Parcellier, A., Brunet, M., Schmitt, E., Col, E., Didelot, C., Hammann, A., Nakayama, K., Nakayama, K., Khochbin, S., Solary, E. & Garrido, C., 6 2006, : : FASEB Journal. 20, 8

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Reentry
S Phase
interphase
Degradation
45 引用 (Scopus)

Identification of novel E2F1 target genes regulated in cell cycle-dependent and independent manners

Iwanaga, R., Komori, H., Ishida, S., Okamura, N., Nakayama, K., Nakayama, K. & Ohtani, K., 3 16 2006, : : Oncogene. 25, 12, p. 1786-1798 13 p.

研究成果: ジャーナルへの寄稿記事

Cell Cycle
Genes
E2F Transcription Factors
Cyclin-Dependent Kinase Inhibitor p27
Gene Expression
14 引用 (Scopus)

Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice

Fotovati, A., Nakayama, K. & Nakayama, K. I., 4 7 2006, : : Cell Division. 1, 4.

研究成果: ジャーナルへの寄稿記事

Germ Cells
Cell Cycle
Cells
Aneuploidy
Apoptosis

Involvement of a novel Q-SNARE, D12, in quality control of the endomembrane system

Okumura, A. J., Hatsuzawa, K., Tamura, T., Nagaya, H., Saeki, K., Okumura, F., Nagao, K., Nishikawa, M., Yoshimura, A. & Wada, I., 2 17 2006, : : Journal of Biological Chemistry. 281, 7, p. 4495-4506 12 p.

研究成果: ジャーナルへの寄稿記事

公開
SNARE Proteins
Quality Control
Qa-SNARE Proteins
Quality control
Lipofuscin
296 引用 (Scopus)

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

Takahashi, A., Ohtani, N., Yamakoshi, K., Iida, S. I., Tahara, H., Nakayama, K., Nakayama, K. I., Ide, T., Saya, H. & Hara, E., 11 1 2006, : : Nature Cell Biology. 8, 11, p. 1291-1297 7 p.

研究成果: ジャーナルへの寄稿記事

Retinoblastoma
Cell Aging
Reactive Oxygen Species
Protein Kinase C
Cell Cycle Checkpoints
73 引用 (Scopus)

Modulation of GABAA receptor phosphorylation and membrane trafficking by phospholipase C-related inactive protein/protein phosphatase 1 and 2A signaling complex underlying brain-derived neurotrophic factor-dependent regulation of GABAergic inhibition

Kanematsu, T., Yasunaga, A., Mizoguchi, Y., Kuratani, A., Kittler, J. T., Jovanovic, J. N., Takenaka, K., Nakayama, K. I., Fukami, K., Takenawa, T., Moss, S. J., Nabekura, J. & Hirata, M., 8 4 2006, : : Journal of Biological Chemistry. 281, 31, p. 22180-22189 10 p.

研究成果: ジャーナルへの寄稿記事

Protein Phosphatase 1
Protein Phosphatase 2
Phosphorylation
Brain-Derived Neurotrophic Factor
Type C Phospholipases
12 引用 (Scopus)

Phosphorylation of extracellular signal-regulated kinase and p27(KIP1) after retinal detachment

Kase, S., Yoshida, K., Harada, T., Harada, C., Namekata, K., Suzuki, Y., Ohgami, K., Shiratori, K., Nakayama, K. I. & Ohno, S., 3 1 2006, : : Graefe's Archive for Clinical and Experimental Ophthalmology. 244, 3, p. 352-358 7 p.

研究成果: ジャーナルへの寄稿記事

Cyclin D1
Extracellular Signal-Regulated MAP Kinases
Retinal Detachment
Phosphorylation
S 10
4 引用 (Scopus)

Phosphorylation of p27(KIP1) in the mitotic cells of the corneal epithelium

Kase, S., Yoshida, K., Ohgami, K., Shiratori, K., Ohno, S. & Nakayama, K. I., 5 1 2006, : : Current Eye Research. 31, 4, p. 307-312 6 p.

研究成果: ジャーナルへの寄稿記事

Corneal Epithelium
Phosphorylation
Staining and Labeling
Immunohistochemistry
Antibodies
41 引用 (Scopus)

PKCδ is necessary for Smad3 expression and transforming growth factor β-induced fibronectin synthesis in vascular smooth muscle cells

Ryer, E. J., Hom, R. P., Sakakibara, K., Nakayama, K., Nakayama, K., Faries, P. L., Liu, B. & Kent, K. C., 4 1 2006, : : Arteriosclerosis, thrombosis, and vascular biology. 26, 4, p. 780-786 7 p.

研究成果: ジャーナルへの寄稿記事

Transforming Growth Factors
Vascular Smooth Muscle
Fibronectins
Smooth Muscle Myocytes
antineoplaston A10
79 引用 (Scopus)

PKCδ regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation

Pula, G., Schuh, K., Nakayama, K., Nakayama, K. I., Walter, U. & Poole, A. W., 12 15 2006, : : Blood. 108, 13, p. 4035-4044 10 p.

研究成果: ジャーナルへの寄稿記事

Pseudopodia
Platelets
Platelet Aggregation
Protein Kinase C
Collagen
38 引用 (Scopus)

Protein kinase C δ activates topoisomerase IIα to induce apoptotic cell death in response to DNA damage

Yoshida, K., Yamaguchi, T., Shinagawa, H., Taira, N., Nakayama, K. I. & Miki, Y., 5 1 2006, : : Molecular and cellular biology. 26, 9, p. 3414-3431 18 p.

研究成果: ジャーナルへの寄稿記事

Type II DNA Topoisomerase
Protein Kinase C
DNA Damage
Cell Death
Chromosome Segregation
125 引用 (Scopus)

Protrudin induces neurite formation by directional membrane trafficking

Shirane, M. & Nakayama, K. I., 11 3 2006, : : Science. 314, 5800, p. 818-821 4 p.

研究成果: ジャーナルへの寄稿記事

Neurites
Guanosine
Membranes
Diphosphates
Extracellular Signal-Regulated MAP Kinases
34 引用 (Scopus)

Regulation of SV40 large T-antigen stability by reversible acetylation

Shimazu, T., Komatsu, Y., Nakayama, K., Fukazawa, H., Horinouchi, S. & Yoshida, M., 11 30 2006, : : Oncogene. 25, 56, p. 7391-7400 10 p.

研究成果: ジャーナルへの寄稿記事

Polyomavirus Transforming Antigens
Viral Tumor Antigens
Acetylation
trichostatin A
Lysine
93 引用 (Scopus)

Suppression of apoptosis in the protein kinase Cδ null mouse in vivo

Humphries, M. J., Limesand, K. H., Schneider, J. C., Nakayama, K. I., Anderson, S. M. & Reyland, M. E., 4 7 2006, : : Journal of Biological Chemistry. 281, 14, p. 9728-9737 10 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Apoptosis
Parotid Gland
Chemical activation
JNK Mitogen-Activated Protein Kinases
32 引用 (Scopus)

Suppression of centrosome amplification after DNA damage depends on p27 accumulation

Sugihara, E., Kanai, M., Saito, S., Nitta, T., Toyoshima, H., Nakayama, K., Nakayama, K. I., Fukasawa, K., Schwab, M., Saya, H. & Miwa, M., 4 15 2006, : : Cancer Research. 66, 8, p. 4020-4029 10 p.

研究成果: ジャーナルへの寄稿記事

Centrosome
DNA Damage
Cyclin-Dependent Kinase 2
SKP Cullin F-Box Protein Ligases
F-Box Proteins
34 引用 (Scopus)

Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCδ-dependent pathway in murine lung

Shukla, A., Barrett, T. F., Nakayama, K., Nakayama, K., Mossman, B. T. & Lounsbury, K. M., 5 2006, : : FASEB Journal. 20, 7

研究成果: ジャーナルへの寄稿記事

asbestos
Asbestos
Up-Regulation
lungs
Lung
276 引用 (Scopus)

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis

Nishitani, H., Sugimoto, N., Roukos, V., Nakanishi, Y., Saijo, M., Obuse, C., Tsurimoto, T., Nakayama, K. I., Nakayama, K., Fujita, M., Lygerou, Z. & Nishimoto, T., 3 8 2006, : : EMBO Journal. 25, 5, p. 1126-1136 11 p.

研究成果: ジャーナルへの寄稿記事

Proteolysis
Ubiquitin-Protein Ligases
G2 Phase
S Phase
Amino Acids
59 引用 (Scopus)

Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis

Gao, Y., Kitagawa, K., Hiramatsu, Y., Kikuchi, H., Isobe, T., Shimada, M., Uchida, C., Hattori, T., Oda, T., Nakayama, K., Nakayama, K. I., Tanaka, T., Konno, H. & Kitagawa, M., 12 15 2006, : : Cancer Research. 66, 24, p. 11623-11631 9 p.

研究成果: ジャーナルへの寄稿記事

G-Protein-Coupled Receptors
Up-Regulation
Down-Regulation
Neoplasm Metastasis
Carcinoma
2005
173 引用 (Scopus)

An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation

Chen, Z., Foster, M. W., Zhang, J., Mao, L., Rockman, H. A., Kawamoto, T., Kitagawa, K., Nakayama, K., Hess, D. T. & Stamler, J. S., 8 23 2005, : : Proceedings of the National Academy of Sciences of the United States of America. 102, 34, p. 12159-12164 6 p.

研究成果: ジャーナルへの寄稿記事

Nitroglycerin
Mitochondria
Blood Vessels
Nitric Oxide
Guanylate Cyclase
70 引用 (Scopus)

Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury

He, C. H., Waxman, A. B., Lee, C. G., Link, H., Rabach, M. E., Ma, B., Chen, Q., Zhu, Z., Zhong, M., Nakayama, K., Nakayama, K. I., Homer, R. & Elias, J. A., 4 2005, : : Journal of Clinical Investigation. 115, 4, p. 1039-1048 10 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-11
Cytoprotection
Acute Lung Injury
Hyperoxia
Cytokines
37 引用 (Scopus)

Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexes

Miyamoto-Sato, E., Ishizaka, M., Horisawa, K., Tateyama, S., Takashima, H., Fuse, S., Sue, K., Hirai, N., Masuoka, K. & Yanagawa, H., 5 1 2005, : : Genome Research. 15, 5, p. 710-717 8 p.

研究成果: ジャーナルへの寄稿記事

Viruses
Proteins
In Vitro Techniques
Leucine Zippers
Sequence Alignment
59 引用 (Scopus)

Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60

Pushkarsky, T., Yurchenko, V., Vanpouille, C., Brichacek, B., Vaisman, I., Hatakeyama, S., Nakayama, K. I., Sherry, B. & Bukrinsky, M. I., 7 29 2005, : : Journal of Biological Chemistry. 280, 30, p. 27866-27871 6 p.

研究成果: ジャーナルへの寄稿記事

Cyclophilins
Proline
Cyclosporine
CD147 Antigens
Cyclophilin A
158 引用 (Scopus)

Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice

Uchida, T., Nakamura, T., Hashimoto, N., Matsuda, T., Kotani, K., Sakaue, H., Kido, Y., Hayashi, Y., Nakayama, K., White, M. F. & Kasuga, M., 2 1 2005, : : Nature medicine. 11, 2, p. 175-182 8 p.

研究成果: ジャーナルへの寄稿記事

Insulin Receptor Substrate Proteins
Insulin-Secreting Cells
Hyperinsulinism
Medical problems
Hyperglycemia
5 引用 (Scopus)

Disappearance of p27(KIP1) and increase in proliferation of the lens cells after extraction of most of the fiber cells of the lens

Kase, S., Yoshida, K., Ikeda, H., Harada, T., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Nakayama, K., Nakayama, K. & Ohno, S., 7 1 2005, : : Current Eye Research. 30, 6, p. 437-442 6 p.

研究成果: ジャーナルへの寄稿記事

Lenses
Cell Proliferation
Epithelial Cells
Bromodeoxyuridine
Capsules
73 引用 (Scopus)

Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2

Wang, H. Q., Nakaya, Y., Du, Z., Yamane, T., Shirane, M., Kudo, T., Takeda, M., Takebayashi, K., Noda, Y., Nakayama, K. & Nishimura, M., 7 1 2005, : : Human Molecular Genetics. 14, 13, p. 1889-1902 14 p.

研究成果: ジャーナルへの寄稿記事

Presenilin-2
Presenilins
Presenilin-1
Apoptosis
Amyloid Precursor Protein Secretases
144 引用 (Scopus)

Large-scale analysis of the human ubiquitin-related proteome

Matsumoto, M., Hatakeyama, S., Oyamada, K., Oda, Y., Nishimura, T. & Nakayama, K. I., 11 1 2005, : : Proteomics. 5, 16, p. 4145-4151 7 p.

研究成果: ジャーナルへの寄稿記事

Proteome
Ubiquitin
Proteins
Ubiquitination
Ribosome Subunits
41 引用 (Scopus)

Mammalian E4 is required for cardiac development and maintenance of the nervous system

Kaneko-Oshikawa, C., Nakagawa, T., Yamada, M., Yoshikawa, H., Matsumoto, M., Yada, M., Hatakeyama, S., Nakayama, K. & Nakayama, K. I., 12 1 2005, : : Molecular and cellular biology. 25, 24, p. 10953-10964 12 p.

研究成果: ジャーナルへの寄稿記事

Nervous System
Maintenance
Endoplasmic Reticulum Stress
Myocardium
Enzymes
67 引用 (Scopus)

Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase

Kotoshibai, S., Kamura, T., Hara, T., Ishida, N. & Nakayama, K., 5 6 2005, : : Journal of Biological Chemistry. 280, 18, p. 17694-17700 7 p.

研究成果: ジャーナルへの寄稿記事

Proteolysis
Dissection
Cyclin E
Ubiquitination
G1 Phase
88 引用 (Scopus)
Thymine DNA Glycosylase
Sumoylation
Proteins
Lysine
Aptitude
34 引用 (Scopus)

p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2

Rodier, G., Makris, C., Coulombe, P., Scime, A., Nakayama, K., Nakayama, K. I. & Meloche, S., 1 3 2005, : : Journal of Cell Biology. 168, 1, p. 55-66 12 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
S Phase
Fibroblasts
Proteolysis
Half-Life
449 引用 (Scopus)

Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice

Takayanagi, Y., Yoshida, M., Bielsky, I. F., Ross, H. E., Kawamata, M., Onaka, T., Yanagisawa, T., Kimura, T., Matzuk, M. M., Young, L. J. & Nishimori, K., 11 1 2005, : : Proceedings of the National Academy of Sciences of the United States of America. 102, 44, p. 16096-16101 6 p.

研究成果: ジャーナルへの寄稿記事

Oxytocin Receptors
Parturition
Oxytocin
Social Behavior
Genes
268 引用 (Scopus)

Phosphorylation of β-catenin by cyclic AMP-dependent protein kinase stabilizes β-catenin through inhibition of its ubiquitination

Hino, S. I., Tanji, C., Nakayama, K. I. & Kikuchi, A., 10 1 2005, : : Molecular and cellular biology. 25, 20, p. 9063-9072 10 p.

研究成果: ジャーナルへの寄稿記事

Catenins
Ubiquitination
Cyclic AMP-Dependent Protein Kinases
Phosphorylation
TCF Transcription Factors
25 引用 (Scopus)

Role of PRIP-1, a novel Ins(1,4,5)P3 binding protein, in Ins(1,4,5)P3-mediated Ca2+ signaling

Harada, K., Takeuchi, H., Oike, M., Matsuda, M., Kanematsu, T., Yagisawa, H., Nakayama, K. I. I., Maeda, K., Erneux, C. & Hirata, M., 2 1 2005, : : Journal of cellular physiology. 202, 2, p. 422-433 12 p.

研究成果: ジャーナルへの寄稿記事

Carrier Proteins
Inositol
Polyphosphates
Enzyme activity
Phosphoric Monoester Hydrolases
62 引用 (Scopus)

Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation

Kotake, Y., Nakayama, K., Ishida, N. & Nakayama, K., 1 14 2005, : : Journal of Biological Chemistry. 280, 2, p. 1095-1102 8 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Serine
Stabilization
Cell Cycle Resting Phase
Mutation
57 引用 (Scopus)

Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle

Hara, T., Kamura, T., Kotoshiba, S., Takahashi, H., Fujiwara, K., Onoyama, I., Shirakawa, M., Mizushima, N. & Nakayama, K. I., 11 1 2005, : : Molecular and cellular biology. 25, 21, p. 9292-9303 12 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
G1 Phase
Ubiquitin
Cell Cycle
Proteins
47 引用 (Scopus)

Suppression of cell migration by protein kinase Cδ

Jackson, D., Zheng, Y., Lyo, D., Shen, Y., Nakayama, K., Nakayama, K. I., Humphries, M. J., Reyland, M. E. & Foster, D. A., 4 21 2005, : : Oncogene. 24, 18, p. 3067-3072 6 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Cell Movement
Fibroblasts
MCF-7 Cells
Eels
41 引用 (Scopus)

Targeted destruction of c-Myc by an engineered ubiquitin ligase suppresses cell transformation and tumor formation

Hatakeyama, S., Watanabe, M., Fujii, Y. & Nakayama, K. I., 9 1 2005, : : Cancer Research. 65, 17, p. 7874-7879 6 p.

研究成果: ジャーナルへの寄稿記事

Ligases
Ubiquitin
Oncogene Proteins
Neoplasms
NIH 3T3 Cells
25 引用 (Scopus)

Ubiquitylation and degradation of serum-inducible kinase by hVPS18, a RING-H2 type ubiquitin ligase

Yogosawa, S., Hatakeyama, S., Nakayama, K., Miyoshi, H., Kohsaka, S. & Akazawa, C., 12 16 2005, : : Journal of Biological Chemistry. 280, 50, p. 41619-41627 9 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Ligases
Ubiquitin
Sorting
Degradation
85 引用 (Scopus)

Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle

Jiang, H., Chang, F. C., Ross, A. E., Lee, J., Nakayama, K., Nakayama, K. & Desiderio, S., 6 10 2005, : : Molecular Cell. 18, 6, p. 699-709 11 p.

研究成果: ジャーナルへの寄稿記事

VDJ Recombinases
Ubiquitination
Cell Cycle
S Phase
SKP Cullin F-Box Protein Ligases
2004
239 引用 (Scopus)

Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice

Furuyama, T., Kitayama, K., Shimoda, Y., Ogawa, M., Sone, K., Yoshida-Araki, K., Hisatsune, H., Nishikawa, S. I., Nakayama, K., Nakayama, K., Ikeda, K., Motoyama, N. & Mori, N., 8 13 2004, : : Journal of Biological Chemistry. 279, 33, p. 34741-34749 9 p.

研究成果: ジャーナルへの寄稿記事

Endothelial cells
Endothelial Cells
Vascular Endothelial Growth Factor A
Embryonic Stem Cells
Stem cells
120 引用 (Scopus)

AIRE Functions as an E3 Ubiquitin Ligase

Uchida, D., Hatakeyama, S., Matsushima, A., Han, H., Ishido, S., Hotta, H., Kudoh, J., Shimizu, N., Doucas, V., Nakayama, K. I., Kuroda, N. & Matsumoto, M., 1 19 2004, : : Journal of Experimental Medicine. 199, 2, p. 167-172 6 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin-Protein Ligases
Self Tolerance
Autoimmune Polyendocrinopathies
Missense Mutation
Proteasome Endopeptidase Complex
174 引用 (Scopus)

ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway

Ohtsuka, T., Ryu, H., Minamishima, Y. A., Macip, S., Sagara, J., Nakayama, K. I., Aaronson, S. A. & Lee, S. W., 2 1 2004, : : Nature Cell Biology. 6, 2, p. 121-128 8 p.

研究成果: ジャーナルへの寄稿記事

Apoptosis
Proteins
Mitochondria
Caspase 2
Caspase 9
135 引用 (Scopus)

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70

Urushitani, M., Kurisu, J., Tateno, M., Hatakeyama, S., Nakayama, K., Kato, S. & Takahashi, R., 7 1 2004, : : Journal of Neurochemistry. 90, 1, p. 231-244 14 p.

研究成果: ジャーナルへの寄稿記事

HSC70 Heat-Shock Proteins
Heat-Shock Proteins
Superoxide Dismutase
Degradation
Proteins