細胞機能制御学部門

研究成果 1989 2020

フィルター
記事
2005
25 引用 (Scopus)

Ubiquitylation and degradation of serum-inducible kinase by hVPS18, a RING-H2 type ubiquitin ligase

Yogosawa, S., Hatakeyama, S., Nakayama, K., Miyoshi, H., Kohsaka, S. & Akazawa, C., 12 16 2005, : : Journal of Biological Chemistry. 280, 50, p. 41619-41627 9 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Ligases
Ubiquitin
Sorting
Degradation
85 引用 (Scopus)

Ubiquitylation of RAG-2 by Skp2-SCF links destruction of the V(D)J recombinase to the cell cycle

Jiang, H., Chang, F. C., Ross, A. E., Lee, J., Nakayama, K., Nakayama, K. & Desiderio, S., 6 10 2005, : : Molecular Cell. 18, 6, p. 699-709 11 p.

研究成果: ジャーナルへの寄稿記事

VDJ Recombinases
Ubiquitination
Cell Cycle
S Phase
SKP Cullin F-Box Protein Ligases
2004
239 引用 (Scopus)

Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice

Furuyama, T., Kitayama, K., Shimoda, Y., Ogawa, M., Sone, K., Yoshida-Araki, K., Hisatsune, H., Nishikawa, S. I., Nakayama, K., Nakayama, K., Ikeda, K., Motoyama, N. & Mori, N., 8 13 2004, : : Journal of Biological Chemistry. 279, 33, p. 34741-34749 9 p.

研究成果: ジャーナルへの寄稿記事

Endothelial cells
Endothelial Cells
Vascular Endothelial Growth Factor A
Embryonic Stem Cells
Stem cells
120 引用 (Scopus)

AIRE Functions as an E3 Ubiquitin Ligase

Uchida, D., Hatakeyama, S., Matsushima, A., Han, H., Ishido, S., Hotta, H., Kudoh, J., Shimizu, N., Doucas, V., Nakayama, K. I., Kuroda, N. & Matsumoto, M., 1 19 2004, : : Journal of Experimental Medicine. 199, 2, p. 167-172 6 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin-Protein Ligases
Self Tolerance
Autoimmune Polyendocrinopathies
Missense Mutation
Proteasome Endopeptidase Complex
174 引用 (Scopus)

ASC is a Bax adaptor and regulates the p53-Bax mitochondrial apoptosis pathway

Ohtsuka, T., Ryu, H., Minamishima, Y. A., Macip, S., Sagara, J., Nakayama, K. I., Aaronson, S. A. & Lee, S. W., 2 1 2004, : : Nature Cell Biology. 6, 2, p. 121-128 8 p.

研究成果: ジャーナルへの寄稿記事

Apoptosis
Proteins
Mitochondria
Caspase 2
Caspase 9
135 引用 (Scopus)

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70

Urushitani, M., Kurisu, J., Tateno, M., Hatakeyama, S., Nakayama, K., Kato, S. & Takahashi, R., 7 1 2004, : : Journal of Neurochemistry. 90, 1, p. 231-244 14 p.

研究成果: ジャーナルへの寄稿記事

HSC70 Heat-Shock Proteins
Heat-Shock Proteins
Superoxide Dismutase
Degradation
Proteins
93 引用 (Scopus)

Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT

Mirza, A. M., Gysin, S., Malek, N., Nakayama, K. I., Roberts, J. M. & McMahon, M., 12 1 2004, : : Molecular and cellular biology. 24, 24, p. 10868-10881 14 p.

研究成果: ジャーナルへの寄稿記事

Cell Cycle Proteins
Protein Kinases
Phosphatidylinositol 3-Kinase
S Phase
Cell Cycle
318 引用 (Scopus)

Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27Kip1 at G1 phase

Kamura, T., Hara, T., Matsumoto, M., Ishida, N., Okumura, F., Hatakeyama, S., Yoshida, M., Nakayama, K. & Nakayama, K., 12 1 2004, : : Nature Cell Biology. 6, 12, p. 1229-1235 7 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
G1 Phase
Ligases
Ubiquitin
Proteolysis
88 引用 (Scopus)

Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C δ

Li, B., Wang, X., Rasheed, N., Hu, Y., Boast, S., Ishii, T., Nakayama, K., Nakayama, K. I. & Golf, S. P., 8 1 2004, : : Genes and Development. 18, 15, p. 1824-1837 14 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Oxidative Stress
Osteoblasts
Peroxiredoxins
DNA Damage
16 引用 (Scopus)

Distribution of p27(KIP1), cylin D1, and proliferating cell nuclear antigen after retinal detachment

Yoshida, K., Kase, S., Nakayama, K., Nagahama, H., Harada, T., Ikeda, H., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Ohno, S. & Nakayama, K., 5 1 2004, : : Graefe's Archive for Clinical and Experimental Ophthalmology. 242, 5, p. 437-441 5 p.

研究成果: ジャーナルへの寄稿記事

Cyclin D1
Proliferating Cell Nuclear Antigen
Retinal Detachment
Retinal Pigment Epithelium
Retina
29 引用 (Scopus)

Down-regulation of p27Kip1 promotes cell proliferation of rat neonatal cardiomyocytes induced by nuclear expression of cyclin D1 and CDK4: Evidence for impaired Skp2-dependent degradation of p27 in terminal differentiation

Tamamori-Adachi, M., Hayashida, K., Nobori, K., Omizu, C., Yamada, K., Sakamoto, N., Kamura, T., Fukuda, K., Ogawa, S., Nakayama, K. I. & Kitajima, S., 11 26 2004, : : Journal of Biological Chemistry. 279, 48, p. 50429-50436 8 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinase 4
Cyclin D1
Cell proliferation
Cardiac Myocytes
Cyclin-Dependent Kinase 2
33 引用 (Scopus)

Early embryonic death in mice lacking the β-catenin-binding protein duplin

Nishiyama, M., Nakayama, K., Tsunematsu, R., Tsukiyama, T., Kikuchi, A. & Nakayama, K. I., 10 1 2004, : : Molecular and cellular biology. 24, 19, p. 8386-8394 9 p.

研究成果: ジャーナルへの寄稿記事

Catenins
Carrier Proteins
Embryonic Structures
Primitive Streak
Wnt Signaling Pathway
268 引用 (Scopus)

Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene

Mao, J. H., Perez-Iosada, J., Wu, D., DelRosario, R., Tsunematsu, R., Nakayama, K. I., Brown, K., Bryson, S. & Balmain, A., 12 9 2004, : : Nature. 432, 7018, p. 775-779 5 p.

研究成果: ジャーナルへの寄稿記事

Tumor Suppressor Genes
Neoplasms
Carcinogenesis
Aurora Kinase A
Radiation
40 引用 (Scopus)

Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis

Okumura, F., Hatakeyama, S., Matsumoto, M., Kamura, T. & Nakayama, K. I., 12 17 2004, : : Journal of Biological Chemistry. 279, 51, p. 53533-53543 11 p.

研究成果: ジャーナルへの寄稿記事

Fasciculation
Ligases
Ubiquitin
Elongation
Proteins
85 引用 (Scopus)

GABAA receptor phospho-dependent modulation is regulated by phospholipase C-related inactive protein type 1, a novel protein phosphatase 1 anchoring protein

Terunuma, M., Jang, I. S., Ha, S. H., Kittler, J. T., Kanematsu, T., Jovanovic, J. N., Nakayama, K. I., Akaike, N., Ryu, S. H., Moss, S. J. & Hirata, M., 8 11 2004, : : Journal of Neuroscience. 24, 32, p. 7074-7084 11 p.

研究成果: ジャーナルへの寄稿記事

Protein Phosphatase 1
Type C Phospholipases
GABA-A Receptors
Proteins
Phosphorylation
4 引用 (Scopus)

Hypersensitivity to pentylenetetrazol-induced convulsion in mice lacking the PLC-related inactive protein-1

Yamaguchi, T., Kubota, T., Kanematsu, T., Nakayama, K., Hirata, M. & Yamamoto, T., 10 29 2004, : : Brain Research. 1025, 1-2, p. 237-240 4 p.

研究成果: ジャーナルへの寄稿記事

Pentylenetetrazole
Type C Phospholipases
Hypersensitivity
Seizures
Proteins
70 引用 (Scopus)

Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones

Hatakeyama, S., Matsumoto, M., Yada, M. & Nakayama, K., 6 1 2004, : : Genes to Cells. 9, 6, p. 533-548 16 p.

研究成果: ジャーナルへの寄稿記事

Molecular Chaperones
Ubiquitin-Protein Ligases
Proteins
Two-Hybrid System Techniques
Proteolysis
45 引用 (Scopus)

In vitro selection of Jun-associated proteins using mRNA display.

Horisawa, K., Tateyama, S., Ishizaka, M., Matsumura, N., Takashima, H., Miyamoto-Sato, E., Doi, N. & Yanagawa, H., 2004, : : Nucleic acids research. 32, 21, p. e169

研究成果: ジャーナルへの寄稿記事

Messenger RNA
Proteins
Technology
In Vitro Techniques
Leucine Zippers
15 引用 (Scopus)

Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body

Yoshida, K., Nakayama, K., Kase, S., Nagahama, H., Harada, T., Ikeda, H., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Ohno, S., Nishi, S. & Nakayama, K. I., 5 1 2004, : : Anatomy and Embryology. 208, 2, p. 145-150 6 p.

研究成果: ジャーナルへの寄稿記事

Ciliary Body
Retinal Pigment Epithelium
Bromodeoxyuridine
Cyclin-Dependent Kinase Inhibitor p27
G1 Phase
23 引用 (Scopus)

Involvement of p27KIP1 in the proliferation of the developing corneal endothelium

Yoshida, K., Kase, S., Nakayama, K., Nagahama, H., Harada, T., Ikeda, H., Harada, C., Imaki, J., Ohgami, K., Shiratori, K., Ilieva, I. B., Ohno, S., Nishi, S. & Nakayama, K. I., 7 1 2004, : : Investigative Ophthalmology and Visual Science. 45, 7, p. 2163-2167 5 p.

研究成果: ジャーナルへの寄稿記事

Corneal Endothelium
Proliferating Cell Nuclear Antigen
Cornea
Parturition
Bromodeoxyuridine
111 引用 (Scopus)

Molecular clearance of ataxin-3 is regulated by a mammalian E4

Matsumoto, M., Yada, M., Hatakeyama, S., Ishimoto, H., Tanimura, T., Tsuji, S., Kakizuka, A., Kitagawa, M. & Nakayama, K. I., 2 11 2004, : : EMBO Journal. 23, 3, p. 659-669 11 p.

研究成果: ジャーナルへの寄稿記事

Machado-Joseph Disease
Degradation
Ubiquitin
Gene therapy
Ubiquitination
188 引用 (Scopus)

Mouse Fbw7/Sel-10/Cdc4 Is Required for Notch Degradation during Vascular Development

Tsunematsu, R., Nakayama, K., Oike, Y., Nishiyama, M., Ishida, N., Hatakeyama, S., Bessho, Y., Kageyama, R., Suda, T. & Nakayama, K., 3 5 2004, : : Journal of Biological Chemistry. 279, 10, p. 9417-9423 7 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Endothelial cells
Blood Vessels
Embryonic Structures
Degradation
475 引用 (Scopus)

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F., Nakayama, K. & Nakayama, K. I., 5 19 2004, : : EMBO Journal. 23, 10, p. 2116-2125 10 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Phosphorylation
Degradation
Ubiquitination
Threonine
264 引用 (Scopus)

Skp2-Mediated degradation of p27 regulates progression into mitosis

Nakayama, K., Nagahama, H., Minamishima, Y. A., Miyake, S., Ishida, N., Hatakeyama, S., Kitagawa, M., Iemura, S. I., Natsume, T. & Nakayama, K. I., 5 1 2004, : : Developmental Cell. 6, 5, p. 661-672 12 p.

研究成果: ジャーナルへの寄稿記事

Mitosis
Degradation
G2 Phase
Proteolysis
Phenotype
88 引用 (Scopus)

Small ubiquitin-like modifier 1 (SUMO-1) modification of the synergy control motif of Ad4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1) regulates synergistic transcription between Ad4BP/SF-1 and Sox9

Komatsu, T., Mizusaki, H., Mukai, T., Ogawa, H., Baba, D., Shirakawa, M., Hatakeyama, S., Nakayama, K. I., Yamamoto, H., Kikuchi, A. & Morohashi, K. I., 10 1 2004, : : Molecular Endocrinology. 18, 10, p. 2451-2462 12 p.

研究成果: ジャーナルへの寄稿記事

Steroidogenic Factor 1
Ubiquitin
Sumoylation
Protein Inhibitors of Activated STAT
STAT1 Transcription Factor
128 引用 (Scopus)

SOCS1 is a suppressor of liver fibrosis and hepatitis-induced carcinogenesis

Yoshida, T., Ogata, H., Kamio, M., Joo, A., Shiraishi, H., Tokunaga, Y., Sata, M., Nagai, H. & Yoshimura, A., 6 21 2004, : : Journal of Experimental Medicine. 199, 12, p. 1701-1707 7 p.

研究成果: ジャーナルへの寄稿記事

Liver Cirrhosis
Hepatitis
Carcinogenesis
Cytokines
Hepatocellular Carcinoma

STAT3 and MITF cooperatively induce cellular transformation through upregulation of c-fos expression

Joo, A., Aburatani, H., Morii, E., Iba, H. & Yoshimura, A., 1 22 2004, : : Oncogene. 23, 3, p. 726-734 9 p.

研究成果: ジャーナルへの寄稿記事

公開
Microphthalmia-Associated Transcription Factor
Up-Regulation
NIH 3T3 Cells
Transcription Factors
STAT Transcription Factors
51 引用 (Scopus)

Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner

Akiyoshi, H., Hatakeyama, S., Pitkänen, J., Mouri, Y., Doucas, V., Kudoh, J., Tsurugaya, K., Uchida, D., Matsushima, A., Oshikawa, K., Nakayama, K., Shimizu, N., Peterson, P. & Matsumoto, M., 8 6 2004, : : Journal of Biological Chemistry. 279, 32, p. 33984-33991 8 p.

研究成果: ジャーナルへの寄稿記事

Proteasome Endopeptidase Complex
Cells
Nuclear Matrix
Cell Line
Cyclic AMP Response Element-Binding Protein
32 引用 (Scopus)

The ISG15 isopeptidase UBP43 is regulated by proteolysis via the SCF Skp2 ubiquitin ligase

Tokarz, S., Berset, C., La Rue, J., Friedman, K., Nakayama, K., Nakayama, K., Zhang, D. E. & Lanker, S., 11 5 2004, : : Journal of Biological Chemistry. 279, 45, p. 46424-46430 7 p.

研究成果: ジャーナルへの寄稿記事

SKP Cullin F-Box Protein Ligases
Proteolysis
Interferon Type I
Ubiquitination
Ligases
57 引用 (Scopus)

The Papillomavirus E7 Oncoprotein Is Ubiquitinated by UbcH7 and Cullin 1- and Skp2-Containing E3 Ligase

Oh, K. J., Kalinina, A., Wang, J., Nakayama, K., Nakayama, K. I. & Bagchi, S., 5 1 2004, : : Journal of virology. 78, 10, p. 5338-5346 9 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin-Protein Ligases
Papillomaviridae
Oncogene Proteins
Ubiquitin
ligases
8 引用 (Scopus)

Tyk2 is essential for IFN-α-induced gene expression in mast cells

Mori, Y., Hirose, K., Suzuki, K., Nakajima, H., Seto, Y., Ikeda, K., Shimoda, K., Nakayama, K. I., Saito, Y. & Iwamoto, I., 6 15 2004, : : International Archives of Allergy and Immunology. 134, SUPPL. 1, p. 25-29 5 p.

研究成果: ジャーナルへの寄稿記事

Mast Cells
Monocyte Chemoattractant Proteins
Gene Expression
Bone Marrow
Bacterial Infections
307 引用 (Scopus)

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

Kamura, T., Maenaka, K., Kotoshiba, S., Matsumoto, M., Kohda, D., Conaway, R. C., Conaway, J. W. & Nakayama, K. I., 12 15 2004, : : Genes and Development. 18, 24, p. 3055-3065 11 p.

研究成果: ジャーナルへの寄稿記事

Suppressor of Cytokine Signaling Proteins
Ligases
Ubiquitin
Cullin Proteins
RNA Interference
2003
110 引用 (Scopus)

A novel route for connexin 43 to inhibit cell proliferation: Negative regulation of S-phase kinase-associated protein (Skp 2)

Zhang, Y. W., Nakayama, K., Nakayama, K. & Morita, I., 4 1 2003, : : Cancer Research. 63, 7, p. 1623-1630 8 p.

研究成果: ジャーナルへの寄稿記事

S-Phase Kinase-Associated Proteins
Connexin 43
Cell Proliferation
Embryonic Structures
Fibroblasts
65 引用 (Scopus)

Association of Cathepsin E Deficiency with Development of Atopic Dermatitis

Tsukuba, T., Okamoto, K., Okamoto, Y., Yanagawa, M., Kohmura, K., Yasuda, Y., Uchi, H., Nakahara, T., Furue, M., Nakayama, K., Kadowaki, T., Yamamoto, K. & Nakayama, K. I., 12 1 2003, : : Journal of biochemistry. 134, 6, p. 893-902 10 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin E
Atopic Dermatitis
Interleukin-18
Interleukin-1
T-cells
68 引用 (Scopus)

Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein

Imaki, H., Nakayama, K., Delehouzee, S., Handa, H., Kitagawa, M., Kamura, T. & Nakayama, K. I., 8 1 2003, : : Cancer Research. 63, 15, p. 4607-4613 7 p.

研究成果: ジャーナルへの寄稿記事

GA-Binding Protein Transcription Factor
Cell Cycle
Electrophoretic Mobility Shift Assay
S Phase
Genetic Promoter Regions
47 引用 (Scopus)

Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a

Kaneko, C., Hatakeyama, S., Matsumoto, M., Yada, M., Nakayama, K. & Nakayama, K., 1 10 2003, : : Biochemical and Biophysical Research Communications. 300, 2, p. 297-304 8 p.

研究成果: ジャーナルへの寄稿記事

Ligases
Ubiquitin
Genes
TATA Box
5' Flanking Region

CIS1 interacts with the Y532 of the prolactin receptor and suppresses prolactin-dependent STAT5 activation

Endo, T., Sasaki, A., Minoguchi, M., Joo, A. & Yoshimura, A., 1 1 2003, : : Journal of biochemistry. 133, 1, p. 109-113 5 p.

研究成果: ジャーナルへの寄稿記事

Prolactin Receptors
Prolactin
Chemical activation
Yeast
Transcription

Control mechanism of JAK/STAT signal transduction pathway

Yamada, S., Shiono, S., Joo, A. & Yoshimura, A., 1 16 2003, : : FEBS Letters. 534, 1-3, p. 190-196 7 p.

研究成果: ジャーナルへの寄稿記事

Janus Kinases
Signal transduction
Transcription
Transducers
Phosphoric Monoester Hydrolases
219 引用 (Scopus)

Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation

Kamura, T., Hara, T., Kotoshiba, S., Yada, M., Ishida, N., Imaki, H., Hatakeyama, S., Nakayama, K. & Nakayama, K. I., 9 2 2003, : : Proceedings of the National Academy of Sciences of the United States of America. 100, 18, p. 10231-10236 6 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Cyclin-Dependent Kinase Inhibitor p57
Cell Cycle
Cyclin E
Ubiquitin-Protein Ligases
129 引用 (Scopus)

Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor γ during bone morphogenetic protein 2-induced adipogenesis

Hata, K., Nishimura, R., Ikeda, F., Yamashita, K., Matsubara, T., Nokubi, T. & Yoneda, T., 2 1 2003, : : Molecular biology of the cell. 14, 2, p. 545-555 11 p.

研究成果: ジャーナルへの寄稿記事

Peroxisome Proliferators
Adipogenesis
Bone Morphogenetic Protein 2
Phosphotransferases
Adipocytes
49 引用 (Scopus)

Enhanced Th2 cell-mediated allergic inflammation in Tyk2-deficient mice

Seto, Y., Nakajima, H., Suto, A., Shimoda, K., Saito, Y., Nakayama, K. I. & Iwamoto, I., 1 15 2003, : : Journal of Immunology. 170, 2, p. 1077-1083 7 p.

研究成果: ジャーナルへの寄稿記事

Th2 Cells
Inflammation
Interleukin-13
Interleukin-12
Eosinophils
84 引用 (Scopus)

Estrogens Down-regulate p27Kip1 in Breast Cancer Cells through Skp2 and through Nuclear Export Mediated by the ERK Pathway

Foster, J. S., Fernando, R. I., Ishida, N., Nakayama, K. I. & Wimalasena, J., 10 17 2003, : : Journal of Biological Chemistry. 278, 42, p. 41355-41366 12 p.

研究成果: ジャーナルへの寄稿記事

Cell Nucleus Active Transport
Extracellular Signal-Regulated MAP Kinases
MCF-7 Cells
Estrogens
Estrogen Receptor Modulators
113 引用 (Scopus)

Glucagon-like peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells

Suzuki, A., Nakauchi, H. & Taniguchi, H., 4 29 2003, : : Proceedings of the National Academy of Sciences of the United States of America. 100, 9, p. 5034-5039 6 p.

研究成果: ジャーナルへの寄稿記事

Epithelial Cells
Insulin
Proglucagon
Glucagon-Like Peptide 1
Pancreas
79 引用 (Scopus)

Impaired degradation of inhibitory subunit of NF-κB (IκB) and β-catenin as a result of targeted disruption of the β-TrCP1 gene

Nakayama, K., Hatakeyama, S., Maruyama, S. I., Kikuchi, A., Onoé, K., Good, R. A. & Nakayama, K. I., 7 22 2003, : : Proceedings of the National Academy of Sciences of the United States of America. 100, 15, p. 8752-8757 6 p.

研究成果: ジャーナルへの寄稿記事

Catenins
Genes
F-Box Proteins
Wnt Signaling Pathway
Polyploidy
22 引用 (Scopus)

Intracellular signal transduction of interferon on the suppression of haematopoietic progenitor cell growth

Kato, K., Kamezaki, K., Shimoda, K., Numata, A., Haro, T., Aoki, K., Ishikawa, F., Takase, K., Ariyama, H., Matsuda, T., Miyamoto, T., Nagafuji, K., Gondo, H., Nakayama, K. I. & Harada, M., 11 1 2003, : : British Journal of Haematology. 123, 3, p. 528-535 8 p.

研究成果: ジャーナルへの寄稿記事

Hematopoietic Stem Cells
Interferons
Signal Transduction
TYK2 Kinase
Growth
13 引用 (Scopus)

Limitin, an interferon-like cytokine, transduces inhibitory signals on B-cell growth through activation of Tyk2, but not Stat1, followed by induction and nuclear translocation of Daxx

Aoki, K., Shimoda, K., Oritani, K., Matsuda, T., Kamezaki, K., Muromoto, R., Numata, A., Tamiya, S., Haro, T., Ishikawa, F., Takase, K., Yamamoto, T., Yumioka, T., Miyamoto, T., Nagafuji, K., Gondo, H., Nagafuchi, S., Nakayama, K. I. & Harada, M., 12 2003, : : Experimental Hematology. 31, 12, p. 1317-1322 6 p.

研究成果: ジャーナルへの寄稿記事

Interferons
B-Lymphocytes
Cytokines
Growth
Interferon Regulatory Factor-1

Mechanisms to control degradation of polyglutamine-containing protein

Nakayama, K. I., 11 1 2003, : : Clinical Neurology. 43, 11, p. 906-908 3 p.

研究成果: ジャーナルへの寄稿記事

Machado-Joseph Disease
Ubiquitination
Proteins
Reticulocytes
Proteasome Endopeptidase Complex
49 引用 (Scopus)

p57KIP2 Modulates Stress-activated Signaling by Inhibiting c-Jun NH2-terminal Kinase/Stress-activated Protein Kinase

Chang, T. S., Kim, M. J., Ryoo, K., Park, J., Eom, S. J., Shim, J., Nakayama, K. I., Nakayama, K., Tomita, M., Takahashi, K., Lee, M. J. & Choi, E. J., 11 28 2003, : : Journal of Biological Chemistry. 278, 48, p. 48092-48098 7 p.

研究成果: ジャーナルへの寄稿記事

JNK Mitogen-Activated Protein Kinases
Heat-Shock Proteins
Protein Kinases
Beckwith-Wiedemann Syndrome
Cyclin-Dependent Kinases
50 引用 (Scopus)

Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1

Oshikawa, K., Matsumoto, M., Yada, M., Kamura, T., Hatakeyama, S. & Nakayama, K. I., 4 18 2003, : : Biochemical and Biophysical Research Communications. 303, 4, p. 1209-1216 8 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
TATA-Box Binding Protein
Ubiquitin-Protein Ligases
Ligases
Ubiquitin

STAP-2/BKS, an adaptor/docking protein, modulates STAT3 activation in acute-phase response through its YXXQ motif

Minoguchi, M., Minoguchi, S., Aki, D., Joo, A., Yamamoto, T., Yumioka, T., Matsuda, T. & Yoshimura, A., 3 28 2003, : : Journal of Biological Chemistry. 278, 13, p. 11182-11189 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Signal Transducing Adaptor Proteins
STAT3 Transcription Factor
Acute-Phase Reaction
Chemical activation
Molecules