細胞機能制御学部門

研究成果 1989 2020

フィルター
記事
2003
353 引用 (Scopus)

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription

Von Der Lehr, N., Johansson, S., Wu, S., Bahram, F., Castell, A., Cetinkaya, C., Hydbring, P., Weidung, I., Nakayama, K., Nakayama, K. I., Söderberg, O., Kerppola, T. K. & Larsson, L. G., 5 1 2003, : : Molecular Cell. 11, 5, p. 1189-1200 12 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
myc Genes
Ubiquitination
Phase Transition
Proteasome Endopeptidase Complex
17 引用 (Scopus)

The second phase activation of protein kinase C δ at late G1 is required for DNA synthesis in serum-induced cell cycle progression

Kitamura, K., Mizuno, K., Etoh, A., Akita, Y., Miyamoto, A., Nakayama, K. & Ohno, S., 4 1 2003, : : Genes to Cells. 8, 4, p. 311-324 14 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Cell Cycle
DNA
Serum
Cell Division
21 引用 (Scopus)

Vasopressin-induced contraction of uterus is mediated solely by the oxytocin receptor in mice, but not in humans

Kawamata, M., Mitsui-Saito, M., Kimura, T., Takayanagi, Y., Yanagisawa, T. & Nishimori, K., 7 11 2003, : : European Journal of Pharmacology. 472, 3, p. 229-234 6 p.

研究成果: ジャーナルへの寄稿記事

Myometrium
Vasopressins
Uterus
Oxytocin
Oxytocin Receptors
2002
112 引用 (Scopus)

Aplidin™ induces the mitochondrial apoptotic pathway via oxidative stress-mediated JNK and p38 activation and protein kinase C δ

García-Fernández, L. F., Losada, A., Alcaide, V., Álvarez, A. M., Cuadrado, A., González, L., Nakayama, K., Nakayama, K., Fernández-Sousa, J. M., Muñoz, A. & Sánchez-Puelles, J. M., 1 1 2002, : : Oncogene. 21, 49, p. 7533-7544 12 p.

研究成果: ジャーナルへの寄稿記事

p38 Mitogen-Activated Protein Kinases
Protein Kinase C
Protein Kinase C-delta
Oxidative Stress
Caspases
385 引用 (Scopus)

CHIP is associated with Parkin, a gene responsible for familial Parkinson's Disease, and enhances its ubiquitin ligase activity

Imai, Y., Soda, M., Hatakeyama, S., Akagi, T., Hashikawa, T., Nakayama, K. I. & Takahashi, R., 1 1 2002, : : Molecular Cell. 10, 1, p. 55-67 13 p.

研究成果: ジャーナルへの寄稿記事

Endoplasmic Reticulum Stress
Ubiquitination
Ligases
Ubiquitin
Parkinson Disease
193 引用 (Scopus)
S-Phase Kinase-Associated Proteins
Proteolysis
Stomach
Carcinoma
Phenotype
312 引用 (Scopus)

Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver

Suzuki, A., Zheng, Y. W., Kaneko, S., Onodera, M., Fukao, K., Nakauchi, H. & Taniguchi, H., 1 7 2002, : : Journal of Cell Biology. 156, 1, p. 173-184 12 p.

研究成果: ジャーナルへの寄稿記事

Pluripotent Stem Cells
Hepatocytes
Liver
Stem Cells
Digestive System Diseases
46 引用 (Scopus)

Cutting edge: Tyk2 is required for the induction and nuclear translocation of Daxx which regulates IFN-α-induced suppression of B lymphocyte formation

Shimoda, K., Kamesaki, K., Numata, A., Aoki, K., Matsuda, T., Oritani, K., Tamiya, S., Kato, K., Takase, K., Imamura, R., Yamamoto, T., Miyamoto, T., Nagafuji, K., Gondo, H., Nagafuchi, S., Nakayama, K. I. & Harada, M., 11 1 2002, : : Journal of Immunology. 169, 9, p. 4707-4711 5 p.

研究成果: ジャーナルへの寄稿記事

B-Lymphocytes
Interleukin-7
B-Lymphoid Precursor Cells
Nuclear Proteins
Up-Regulation
54 引用 (Scopus)

Diminished alcohol preference in transgenic mice lacking aldehyde dehydrogenase activity

Isse, T., Oyama, T., Kitagawa, K., Matsuno, K., Matsumoto, A., Yoshida, A., Nakayama, K., Nakayama, K. & Kawamoto, T., 11 1 2002, : : Pharmacogenetics. 12, 8, p. 621-626 6 p.

研究成果: ジャーナルへの寄稿記事

Aldehyde Dehydrogenase
Transgenic Mice
Alcohols
Acetaldehyde
Ethanol
24 引用 (Scopus)

Formation of Mallory body-like inclusions and cell death induced by deregulated expression of keratin 18

Nakamichi, I., Hatakeyama, S. & Nakayama, K. I., 10 1 2002, : : Molecular biology of the cell. 13, 10, p. 3441-3451 11 p.

研究成果: ジャーナルへの寄稿記事

Mallory Bodies
Keratin-18
Cell Death
Keratin-8
Griseofulvin
11 引用 (Scopus)

Glomerular differentiation in p27 and p57 double-mutant metanephroi

Tomari, S., Nagahama, H., Shu, Y., Hoshi, S., Nakayama, K., Nakayama, K. & Nagata, M., 2002, : : Anatomy and Embryology. 206, 1-2, p. 31-36 6 p.

研究成果: ジャーナルへの寄稿記事

Podocytes
Organ Culture Techniques
Foot
Histology
Cell Cycle
329 引用 (Scopus)

Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cδ

Miyamoto, A., Nakayama, K., Imaki, H., Hirose, S., Jiang, Y., Abe, M., Tsukiyama, T., Nagahama, H., Ohno, S., Hatakeyama, S. & Nakayama, K. I., 4 25 2002, : : Nature. 416, 6883, p. 865-869 5 p.

研究成果: ジャーナルへの寄稿記事

Protein Kinase C
Immunity
B-Lymphocytes
CCAAT-Enhancer-Binding Protein-beta
Germinal Center
9 引用 (Scopus)

Isolation and characterization of a novel F-box protein Pof10 in fission yeast

Ikebe, C., Nakayama, K. I., Ikebe, C., Kominami, K. I., Nakayama, K. I., Kominami, K. I., Nakayama, K. I. & Toda, T., 1 1 2002, : : Biochemical and Biophysical Research Communications. 290, 5, p. 1399-1407 9 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Schizosaccharomyces
Yeast
Two-Hybrid System Techniques
Ubiquitin-Protein Ligases
37 引用 (Scopus)

Modulation of astrocyte proliferation by cyclin-dependent kinase inhibitor p27Kip1

Koguchi, K., Nakatsuji, Y., Nakayama, K. & Sakoda, S., 3 4 2002, : : GLIA. 37, 2, p. 93-104 12 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinases
Astrocytes
Gliosis
Contact Inhibition
Cyclin A
58 引用 (Scopus)

Partial impairment of interleukin-12 (IL-12) and IL-18 signaling in Tyk2-deficient mice

Shimoda, K., Tsutsui, H., Aoki, K., Kato, K., Matsuda, T., Numata, A., Takase, K., Yamamoto, T., Nukina, H., Hoshino, T., Asano, Y., Gondo, H., Okamura, T., Okamura, S., Nakayama, K. I., Nakanishi, K., Niho, Y. & Harada, M., 3 15 2002, : : Blood. 99, 6, p. 2094-2099 6 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-18
Interleukin-12
Natural Killer Cells
Interferons
Interleukin-18 Receptors
229 引用 (Scopus)

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

Ishida, N., Hara, T., Kamura, T., Yoshida, M., Nakayama, K. & Nakayama, K., 4 26 2002, : : Journal of Biological Chemistry. 277, 17, p. 14355-14358 4 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Cell Nucleus Active Transport
Serine
SKP Cullin F-Box Protein Ligases
Substitution reactions
19 引用 (Scopus)

Polymorphism analysis of the upstream region of the human N-methyl-D-aspartate receptor subunit NR1 gene (GRIN1): Implications for schizophrenia

Tani, A., Kikuta, R., Itoh, K., Joo, A., Shibata, H., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 11 1 2002, : : Schizophrenia research. 58, 1, p. 83-86 4 p.

研究成果: ジャーナルへの寄稿記事

N-Methyl-D-Aspartate Receptors
Schizophrenia
Single Nucleotide Polymorphism
Genes
Initiator Codon
54 引用 (Scopus)

Recovery of liver mass without proliferation of hepatocytes after partial hepatectomy in Skp2-deficient mice

Minamishima, Y. A., Nakayama, K. & Nakayama, K., 2002, : : Cancer Research. 62, 4, p. 995-999 5 p.

研究成果: ジャーナルへの寄稿記事

Hepatectomy
Hepatocytes
Polyploidy
Cell Proliferation
Liver
107 引用 (Scopus)

Role of the PLC-related, catalytically inactive protein p130 in GABAA receptor function

Kanematsu, T., Jang, I. S., Yamaguchi, T., Nagahama, H., Yoshimura, K., Hidaka, K., Matsuda, M., Takeuchi, H., Misumi, Y., Nakayama, K., Yamamoto, T., Akaike, N., Hirata, M. & Nakayama, K., 3 1 2002, : : EMBO Journal. 21, 5, p. 1004-1011 8 p.

研究成果: ジャーナルへの寄稿記事

GABA-A Receptors
Programmable logic controllers
Proteins
Diazepam
gamma-Aminobutyric Acid
2001
30 引用 (Scopus)

Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia

Shibata, H., Joo, A., Fujii, Y., Tani, A., Makino, C., Hirata, N., Kikuta, R., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 10 30 2001, : : Psychiatric Genetics. 11, 3, p. 139-144 6 p.

研究成果: ジャーナルへの寄稿記事

Single Nucleotide Polymorphism
Schizophrenia
Genes
Haplotypes
Polymerase Chain Reaction
21 引用 (Scopus)

Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10

Maruyama, S. I., Hatakeyama, S., Nakayama, K., Ishida, N., Kawakami, K. & Nakayama, K. I., 9 15 2001, : : Genomics. 78, 3, p. 214-222 9 p.

研究成果: ジャーナルへの寄稿記事

Caenorhabditis elegans
F-Box Proteins
Presenilins
Genes
Proteins
28 引用 (Scopus)

Deafness due to degeneration of cochlear neurons in caspase-3-deficient mice

Morishita, H., Makishima, T., Kaneko, C., Lee, Y. S., Segil, N., Takahashi, K., Kuraoka, A., Nakagawa, T., Nabekura, J., Nakayama, K. & Nakayama, K. I., 1 1 2001, : : Biochemical and Biophysical Research Communications. 284, 1, p. 142-149 8 p.

研究成果: ジャーナルへの寄稿記事

Nerve Degeneration
Cochlea
Deafness
Caspase 3
Neurons
185 引用 (Scopus)

Degradation of p27Kip1 at the G0-G1 Transition Mediated by a Skp2-independent Ubiquitination Pathway

Hara, T., Kamura, T., Nakayama, K., Oshikawa, K., Hatakeyama, S. & Nakayama, K., 12 28 2001, : : Journal of Biological Chemistry. 276, 52, p. 48937-48943 7 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Cell Cycle
Cells
Proteolysis
Degradation
50 引用 (Scopus)

Down-regulation of p27Kip1 expression is required for development and function of T cells

Tsukiyama, T., Ishida, N., Shirane, M., Minamishima, Y. A., Hatakeyama, S., Kitagawa, M., Nakayama, K. & Nakayama, K. I., 1 1 2001, : : Journal of Immunology. 166, 1, p. 304-312 9 p.

研究成果: ジャーナルへの寄稿記事

Down-Regulation
T-Lymphocytes
Thymocytes
Cell Lineage
Transgenic Mice
91 引用 (Scopus)

Essential role of the prosurvival bcl-2 homologue A1 in mast cell survival after allergic activation

Xiang, Z., Ahmed, A. A., Möller, C., Nakayama, K. I., Hatakeyama, S. & Nilsson, G., 12 3 2001, : : Journal of Experimental Medicine. 194, 11, p. 1561-1569 9 p.

研究成果: ジャーナルへの寄稿記事

Mast Cells
Cell Survival
Hypersensitivity
p-Methoxy-N-methylphenethylamine
IgE Receptors
13 引用 (Scopus)

Hyperinsulinemia in PRIP-1 gene deleted mice

Doira, N., Kanematsu, T., Matsuda, M., Takeuchi, H., Nakano, H. O., Ito, Y., Nakayama, K., Nakayama, K. I. & Hirata, M., 1 1 2001, : : Biomedical Research. 22, 3, p. 157-165 9 p.

研究成果: ジャーナルへの寄稿記事

Hyperinsulinism
Programmable logic controllers
Genes
Type C Phospholipases
Protein Phosphatase 1
4 引用 (Scopus)

Morphologic and molecular analysis of estrogen-induced pituitary tumorigenesis in targeted disruption of transforming growth factor-β receptor type II and/or p27 mice

Ikeda, H., Yoshimoto, T., Shida, N., Miyoshi, I., Nakayama, K., Nakayama, K., Oshima, M. & Taketo, M. M., 1 1 2001, : : Endocrine. 16, 1, p. 55-65 11 p.

研究成果: ジャーナルへの寄稿記事

Growth Factor Receptors
Transforming Growth Factors
Estrogens
Carcinogenesis
Pituitary Gland
40 引用 (Scopus)

Regulation of the Level of Vesl-1S/Homer-1a Proteins by Ubiquitin-Proteasome Proteolytic Systems

Ageta, H., Kato, A., Hatakeyama, S., Nakayama, K., Isojima, Y. & Sugiyama, H., 5 11 2001, : : Journal of Biological Chemistry. 276, 19, p. 15893-15897 5 p.

研究成果: ジャーナルへの寄稿記事

Proteasome Endopeptidase Complex
Ubiquitin
Proteasome Inhibitors
Proteins
Brain
81 引用 (Scopus)

Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27Kip1 and p57Kip2 during mouse development

Nagahama, H., Hatakeyama, S., Nakayama, K., Nagata, M., Tomita, K. & Nakayama, K., 3 19 2001, : : Anatomy and Embryology. 203, 2, p. 77-87 11 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinases
Embryonic Development
Cyclin-Dependent Kinase Inhibitor p57
Phenotype
Palate
43 引用 (Scopus)

Structure and polymorphisms of the human metabotropic glutamate receptor type 2 gene (GRM2): Analysis of association with schizophrenia

Joo, A., Shibata, H., Ninomiya, H., Kawasaki, H., Tashiro, N. & Fukumaki, Y., 3 14 2001, : : Molecular Psychiatry. 6, 2, p. 186-192 7 p.

研究成果: ジャーナルへの寄稿記事

Schizophrenia
Genes
Exons
eglumetad
Radiation Hybrid Mapping
246 引用 (Scopus)

The SOCS Box of SOCS-1 Accelerates Ubiquitin-dependent Proteolysis of TEL-JAK2

Kamizono, S., Hanada, T., Yasukawa, H., Minoguchi, S., Kato, R., Minoguchi, M., Hattori, K., Hatakeyama, S., Yada, M., Morita, S., Kitamura, T., Kato, H., Nakayama, K. I. & Yoshimura, A., 4 20 2001, : : Journal of Biological Chemistry. 276, 16, p. 12530-12538 9 p.

研究成果: ジャーナルへの寄稿記事

Cullin Proteins
Proteolysis
Ubiquitin
Protein-Tyrosine Kinases
Genes
425 引用 (Scopus)

U Box Proteins as a New Family of Ubiquitin-Protein Ligases

Hatakeyama, S., Yada, M., Matsumoto, M., Ishida, N. & Nakayama, K. I., 8 31 2001, : : Journal of Biological Chemistry. 276, 35, p. 33111-33120 10 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin-Protein Ligases
Ubiquitin
Fungal Proteins
Ubiquitination
Enzymes
2000
408 引用 (Scopus)

Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice

Takai, H., Tominaga, K., Motoyama, N., Minamishima, Y. A., Nagahama, H., Tsukiyama, T., Ikeda, K., Nakayama, K., Nakanishi, M. & Nakayama, K., 6 15 2000, : : Genes and Development. 14, 12, p. 1439-1447 9 p.

研究成果: ジャーナルへの寄稿記事

Cell Cycle Checkpoints
Mammals
Blastocyst
DNA Damage
Embryonic Structures
101 引用 (Scopus)

Aldehyde dehydrogenase (ALDH) 2 associates with oxidation of methoxyacetaldehyde; in vitro analysis with liver subcellular fraction derived from human and Aldh2 gene targeting mouse

Kitagawa, K., Kawamoto, T., Kunugita, N., Tsukiyama, T., Okamoto, K., Yoshida, A., Nakayama, K. & Nakayama, K. I., 7 7 2000, : : FEBS Letters. 476, 3, p. 306-311 6 p.

研究成果: ジャーナルへの寄稿記事

Aldehyde Dehydrogenase
Subcellular Fractions
Gene Targeting
Liver
Genes
42 引用 (Scopus)

Cell cycle-dependent expression of mammalian E2-C regulated by the anaphase-promoting complex/cyclosome

Yamanaka, A., Hatakeyama, S., Kominami, K. I., Kitagawa, M., Matsumoto, M. & Nakayama, K. I., 1 1 2000, : : Molecular biology of the cell. 11, 8, p. 2821-2831 11 p.

研究成果: ジャーナルへの寄稿記事

Anaphase-Promoting Complex-Cyclosome
Cell Division
Cell Cycle
Ubiquitins
Polyubiquitin
266 引用 (Scopus)

Flow-cytometric separation and enrichment of hepatic progenitor cells in the developing mouse liver

Suzuki, A., Zheng, Y. W., Kondo, R., Kusakabe, M., Takada, Y., Fukao, K., Nakauchi, H. & Taniguchi, H., 1 1 2000, : : Hepatology. 32, 6, p. 1230-1239 10 p.

研究成果: ジャーナルへの寄稿記事

Hepatocytes
Stem Cells
Liver
Integrin alpha6beta1
Flow Cytometry
70 引用 (Scopus)

Hematin polymerization assay as a high-throughput screen for identification of new antimalarial pharmacophores

Kurosawa, Y., Dorn, A., Kitsuji-Shirane, M., Shimada, H., Satoh, T., Matile, H., Hofheinz, W., Masciadri, R., Kansy, M. & Ridley, R. G., 1 1 2000, : : Antimicrobial Agents and Chemotherapy. 44, 10, p. 2638-2644 7 p.

研究成果: ジャーナルへの寄稿記事

Hemin
Antimalarials
Polymerization
Plasmodium berghei
Scintillation Counting
101 引用 (Scopus)

Mice lacking a CDK inhibitor, p57(Kip2), exhibit skeletal abnormalities and growth retardation

Takahashi, K., Nakayama, K. I. & Nakayama, K., 1 1 2000, : : Journal of biochemistry. 127, 1, p. 73-83 11 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinase Inhibitor p57
Tumors
Genes
Cyclin-Dependent Kinases
Fibroblasts
275 引用 (Scopus)

NAK is an IκB kinase-activating kinase

Tojima, Y., Fujimoto, A., Delhase, M., Chen, Y., Hatekeyama, S., Nakayama, K. I., Kaneko, Y., Nimura, Y., Motoyama, N., Ikeda, K., Karin, M. & Nakanishi, M., 4 13 2000, : : Nature. 404, 6779, p. 778-782 5 p.

研究成果: ジャーナルへの寄稿記事

Phosphotransferases
Phosphorylation
Protein Kinase C
Intercellular Signaling Peptides and Proteins
Phorbol Esters
172 引用 (Scopus)

Phosphorylation at serine 10, a major phosphorylation site of p27(Kip1), increases its protein stability

Ishida, N., Kitagawa, M., Hatakeyama, S. & Nakayama, K., 8 18 2000, : : Journal of Biological Chemistry. 275, 33, p. 25146-25154 9 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Protein Stability
Serine
Proteins
Cyclin-Dependent Kinase Inhibitor p27
586 引用 (Scopus)

Targeted disruption of Skp2 results in accumulation of cyclin E and p27 (Kip1), polyploidy and centrosome overduplication

Nakayama, K., Nagahama, H., Minamishima, Y. A., Matsumoto, M., Nakamichi, I., Kitagawa, K., Shirane, M., Tsunematsu, R., Tsukiyama, T., Ishida, N., Kitagawa, M., Nakayama, K. I. & Hatakeyama, S., 5 2 2000, : : EMBO Journal. 19, 9, p. 2069-2081 13 p.

研究成果: ジャーナルへの寄稿記事

Cyclin E
Centrosome
Polyploidy
SKP Cullin F-Box Protein Ligases
Ubiquitin
234 引用 (Scopus)

Tyk2 plays a restricted role in IFNα signaling, although it is required for IL-12-mediated T cell function

Shimoda, K., Kato, K., Aoki, K., Matsuda, T., Miyamoto, A., Shibamori, M., Yamashita, M., Numata, A., Takase, K., Kobayashi, S., Shibata, S., Asano, Y., Gondo, H., Sekiguchi, K., Nakayama, K., Nakayama, T., Okamura, T., Okamura, S., Niho, Y. & Nakayama, K. I., 1 1 2000, : : Immunity. 13, 4, p. 561-571 11 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-12
Janus Kinases
T-Lymphocytes
Cytokine Receptors
Interleukin-10

Ubiquitin-dependent proteolysis by SCF complex

Nakayama, K. & Nakayama, K. I., 12 1 2000, : : Seikagaku. 72, 2, p. 113-117 5 p.

研究成果: ジャーナルへの寄稿記事

Cysteine Endopeptidases
SKP Cullin F-Box Protein Ligases
Ubiquitins
Peptide Synthases
Multienzyme Complexes
1999
445 引用 (Scopus)

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of β-catenin

Kitagawa, M., Hatakeyama, S., Shirane, M., Matsumoto, M., Ishida, N., Hattori, K., Nakamichi, I., Kikuchi, A., Nakayama, K. & Nakayama, K., 5 4 1999, : : EMBO Journal. 18, 9, p. 2401-2410 10 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Proteolysis
Catenins
Ubiquitin
Ubiquitination
18 引用 (Scopus)

Bcl-xL is a negative regulator of caspase-3 activation in immature neurons during development

Urase, K., Momoi, T., Fujita, E., Isahara, K., Uchiyama, Y., Tokunaga, A., Nakayama, K. & Motoyama, N., 8 5 1999, : : Developmental Brain Research. 116, 1, p. 69-78 10 p.

研究成果: ジャーナルへの寄稿記事

Caspase 3
Neurons
Rhombencephalon
Caspases
Nervous System
60 引用 (Scopus)

Common pathway for the ubiquitination of IκBα, Iκbβ, and IκBε mediated by the F-box protein FWD1

Shirane, M., Hatakeyama, S., Hattori, K., Nakayama, K. & Nakayama, K., 10 1 1999, : : Journal of Biological Chemistry. 274, 40, p. 28169-28174 6 p.

研究成果: ジャーナルへの寄稿記事

F-Box Proteins
Ubiquitination
Proteins
SKP Cullin F-Box Protein Ligases
Proteolysis
210 引用 (Scopus)

Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing

Shirane, M., Harumiya, Y., Ishida, N., Hirai, A., Miyamoto, C., Hatakeyama, S., Nakayama, K. I. & Kitagawa, M., 5 14 1999, : : Journal of Biological Chemistry. 274, 20, p. 13886-18893 5008 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin
Down-Regulation
Ubiquitination
Degradation
Processing
34 引用 (Scopus)

Molecular dissection of the interactions among IκBα, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IκBα

Hattori, K., Hatakeyama, S., Shirane, M., Matsumoto, M. & Nakayama, K. I., 10 15 1999, : : Journal of Biological Chemistry. 274, 42, p. 29641-29647 7 p.

研究成果: ジャーナルへの寄稿記事

Proteolysis
Dissection
Phosphorylation
Ubiquitination
Ubiquitin
31 引用 (Scopus)

pRb phosphorylation is regulated differentially by cyclin-dependent kinase (Cdk) 2 and Cdk4 in retinoic acid-induced neuronal differentiation of P19 cells

Watanabe, Y., Watanabe, T., Kitagawa, M., Taya, Y., Nakayama, K. & Motoyama, N., 9 25 1999, : : Brain Research. 842, 2, p. 342-350 9 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinase 2
Tretinoin
Cell Differentiation
Phosphorylation
Phosphotransferases
16 引用 (Scopus)

Structure and expression of the gene encoding mouse F-box protein, Fwd2

Miura, M., Hatakeyama, S., Hattori, K. & Nakayama, K. I., 11 15 1999, : : Genomics. 62, 1, p. 50-58 9 p.

研究成果: ジャーナルへの寄稿記事

SKP Cullin F-Box Protein Ligases
F-Box Proteins
Gene Expression
Complementary DNA
Cullin Proteins