細胞機能制御学部門

研究成果 1989 2020

フィルター
記事
2015
1 引用 (Scopus)

Liver maturation deficiency in p57Kip2-/- mice occurs in a hepatocytic p57Kip2 expression-independent manner

Yanagida, A., Chikada, H., Ito, K., Umino, A., Kato-Itoh, M., Yamazaki, Y., Sato, H., Kobayashi, T., Yamaguchi, T., Nakayama, K. I., Nakauchi, H. & Kamiya, A., 11 15 2015, : : Developmental Biology. 407, 2, p. 331-343 13 p.

研究成果: ジャーナルへの寄稿記事

Hepatocytes
Cell Cycle
Liver
Stem Cells
Cell Proliferation
18 引用 (Scopus)

Maternal TET3 is dispensable for embryonic development but is required for neonatal growth

Tsukada, Y. I., Akiyama, T. & Nakayama, K. I., 10 28 2015, : : Scientific reports. 5, 15876.

研究成果: ジャーナルへの寄稿記事

5-Methylcytosine
Zygote
Embryonic Development
Mothers
DNA Methylation
12 引用 (Scopus)

Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: Involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of Thr176 in GATA-binding protein 2

Nakajima, T., Kitagawa, K., Ohhata, T., Sakai, S., Uchida, C., Shibata, K., Minegishi, N., Yumimoto, K., Nakayama, K. I., Masumoto, K., Katou, F., Niida, H. & Kitagawa, M., 4 17 2015, : : Journal of Biological Chemistry. 290, 16, p. 10368-10381 14 p.

研究成果: ジャーナルへの寄稿記事

GATA2 Transcription Factor
CDC2 Protein Kinase
Cyclin B
Phosphorylation
Ubiquitin
15 引用 (Scopus)

Role of the Atg9a gene in intrauterine growth and survival of fetal mice

Kojima, T., Yamada, T., Akaishi, R., Furuta, I., Saitoh, T., Nakabayashi, K., Nakayama, K. I., Nakayama, K., Akira, S. & Minakami, H., 9 1 2015, : : Reproductive Biology. 15, 3, p. 131-138 8 p.

研究成果: ジャーナルへの寄稿記事

Fetal Development
mice
Genes
genes
hypertension
26 引用 (Scopus)

SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination

Lu, W., Liu, S., Li, B., Xie, Y., Adhiambo, C., Yang, Q., Ballard, B. R., Nakayama, K. I., Matusik, R. J. & Chen, Z., 1 1 2015, : : Oncotarget. 6, 2, p. 771-788 18 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitination
Prostate
Prostatic Neoplasms
Carcinogenesis
TNF Receptor-Associated Factor 6
116 引用 (Scopus)

Slowly dividing neural progenitors are an embryonic origin of adult neural stem cells

Furutachi, S., Miya, H., Watanabe, T., Kawai, H., Yamasaki, N., Harada, Y., Imayoshi, I., Nelson, M., Nakayama, K. I., Hirabayashi, Y. & Gotoh, Y., 4 28 2015, : : Nature Neuroscience. 18, 5, p. 657-665 9 p.

研究成果: ジャーナルへの寄稿記事

Adult Stem Cells
Neural Stem Cells
Stem Cells
Histones
Cyclin-Dependent Kinase Inhibitor p57
18 引用 (Scopus)
Histones
Chromatin
Pseudogenes
Genome
Genes
4 引用 (Scopus)

Two inhibitory systems and CKIs regulate cell cycle exit of mammalian cardiomyocytes after birth

Tane, S., Okayama, H., Ikenishi, A., Amemiya, Y., Nakayama, K. & Takeuchi, T., 10 16 2015, : : Biochemical and Biophysical Research Communications. 466, 2, p. 147-154 8 p.

研究成果: ジャーナルへの寄稿記事

Cardiac Myocytes
Cell Cycle
Cells
Parturition
Cell Division
2016
11 引用 (Scopus)

Akt1-mediated Gata3 phosphorylation controls the repression of IFNÎ 3 in memory-type Th2 cells

Hosokawa, H., Tanaka, T., Endo, Y., Kato, M., Shinoda, K., Suzuki, A., Motohashi, S., Matsumoto, M., Nakayama, K. I. & Nakayama, T., 4 7 2016, : : Nature communications. 7, 11289.

研究成果: ジャーナルへの寄稿記事

Th2 Cells
phosphorylation
Phosphorylation
Cytokines
Data storage equipment
3 引用 (Scopus)

ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation

Uematsu, K., Okumura, F., Tonogai, S., Joo-Okumura, A., Alemayehu, D. H., Nishikimi, A., Fukui, Y., Nakatsukasa, K. & Kamura, T., 1 1 2016, : : Journal of Cell Biology. 215, 1, 95.

研究成果: ジャーナルへの寄稿記事

Microtubules
Suppressor of Cytokine Signaling Proteins
Cullin Proteins
Genome
Mitosis
79 引用 (Scopus)

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

Katayama, Y., Nishiyama, M., Shoji, H., Ohkawa, Y., Kawamura, A., Sato, T., Suyama, M., Takumi, T., Miyakawa, T. & Nakayama, K. I., 1 1 2016, : : Nature. 537, 7622, p. 675-679 5 p.

研究成果: ジャーナルへの寄稿記事

Haploinsufficiency
Phenotype
Transcription Factors
Genes
Brain
3 引用 (Scopus)

Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation

Niikura, K., Horisawa, K. & Doi, N., 1 1 2016, : : Journal of biochemistry. 159, 1, p. 123-132 10 p.

研究成果: ジャーナルへの寄稿記事

Single-Chain Antibodies
Epidermal Growth Factor Receptor
Peptides
Sea Urchins
Antibodies
1 引用 (Scopus)

FBXL12 regulates T-cell differentiation in a cell-autonomous manner

Nita, A., Nishiyama, M., Muto, Y. & Nakayama, K., 5 1 2016, : : Genes to Cells. 21, 5, p. 517-524 8 p.

研究成果: ジャーナルへの寄稿記事

Cell Differentiation
T-Lymphocytes
Thymus Gland
Placentation
Aldehyde Dehydrogenase
16 引用 (Scopus)

FBXW7 is involved in the acquisition of the malignant phenotype in epithelial ovarian tumors

Kitade, S., Onoyama, I., Kobayashi, H., Yagi, H., Yoshida, S., Kato, M., Tsunematsu, R., Asanoma, K., Sonoda, K., Wake, N., Hata, K., Nakayama, K. I. & Kato, K., 10 1 2016, : : Cancer Science. 107, 10, p. 1399-1405 7 p.

研究成果: ジャーナルへの寄稿記事

Ovarian Neoplasms
Phenotype
p53 Genes
DNA Methylation
Neoplasms
9 引用 (Scopus)

Generation of a novel transgenic rat model for tracing extracellular vesicles in body fluids

Yoshimura, A., Kawamata, M., Yoshioka, Y., Katsuda, T., Kikuchi, H., Nagai, Y., Adachi, N., Numakawa, T., Kunugi, H., Ochiya, T. & Tamai, Y., 8 19 2016, : : Scientific reports. 6, 31172.

研究成果: ジャーナルへの寄稿記事

Transgenic Rats
Body Fluids
Green Fluorescent Proteins
Extracellular Vesicles
Endosomes
3 引用 (Scopus)

Identification of low-abundance proteins in serum via the isolation of HSP72 complexes

Tanaka, M., Shiota, M., Nakao, T., Uemura, R., Nishi, S., Ohkawa, Y., Matsumoto, M., Yamaguchi, M., Osada-Oka, M., Inagaki, A., Takahashi, K., Nakayama, K. I., Gi, M., Izumi, Y., Miura, K. & Iwao, H., 3 16 2016, : : Journal of Proteomics. 136, p. 214-221 8 p.

研究成果: ジャーナルへの寄稿記事

HSP72 Heat-Shock Proteins
Blood Proteins
Multiple Myeloma
Proteins
Tumors
35 引用 (Scopus)

Inhibition of CBLB protects from lethal Candida albicans sepsis

Wirnsberger, G., Zwolanek, F., Asaoka, T., Kozieradzki, I., Tortola, L., Wimmer, R. A., Kavirayani, A., Fresser, F., Baier, G., Langdon, W. Y., Ikeda, F., Kuchler, K. & Penninger, J. M., 8 1 2016, : : Nature medicine. 22, 8, p. 915-923 9 p.

研究成果: ジャーナルへの寄稿記事

C-Type Lectins
Candida
Candida albicans
Sepsis
Mycoses
4 引用 (Scopus)

Kupffer cells induce Notch-mediated hepatocyte conversion in a common mouse model of intrahepatic cholangiocarcinoma

Terada, M., Horisawa, K., Miura, S., Takashima, Y., Ohkawa, Y., Sekiya, S., Matsuda-Ito, K. & Suzuki, A., 10 4 2016, : : Scientific reports. 6, 34691.

研究成果: ジャーナルへの寄稿記事

Kupffer Cells
Cholangiocarcinoma
Hepatocytes
Liver
Intrahepatic Bile Ducts
10 引用 (Scopus)

Linear ubiquitination by LUBEL has a role in Drosophila heat stress response

Asaoka, T., Almagro, J., Ehrhardt, C., Tsai, I., Schleiffer, A., Deszcz, L., Junttila, S., Ringrose, L., Mechtler, K., Kavirayani, A., Gyenesei, A., Hofmann, K., Duchek, P., Rittinger, K. & Ikeda, F., 11 1 2016, : : EMBO Reports. 17, 11, p. 1624-1640 17 p.

研究成果: ジャーナルへの寄稿記事

公開
Heat-Shock Response
Ubiquitin-Protein Ligases
Ubiquitination
Drosophila
Diptera
5 引用 (Scopus)

Myofibroblasts Derived from Hepatic Progenitor Cells Create the Tumor Microenvironment

Sekiya, S., Miura, S., Matsuda-Ito, K. & Suzuki, A., 12 13 2016, : : Stem Cell Reports. 7, 6, p. 1130-1139 10 p.

研究成果: ジャーナルへの寄稿記事

Tumor Microenvironment
Myofibroblasts
Tumors
Hepatocytes
Stem Cells
5 引用 (Scopus)

p57Kip2 knock-in mouse reveals CDK-independent contribution in the development of Beckwith–Wiedemann syndrome

Duquesnes, N., Callot, C., Jeannot, P., Daburon, V., Nakayama, K. I., Manenti, S., Davy, A. & Besson, A., 7 1 2016, : : Journal of Pathology. 239, 3, p. 250-261 12 p.

研究成果: ジャーナルへの寄稿記事

Inborn Genetic Diseases
Point Mutation
Epigenomics
Neoplasms
Cell Cycle
8 引用 (Scopus)

Parallel regulation of von Hippel-Lindau disease by pVHL-mediated degradation of B-Myb and hypoxia-inducible factor α

Okumura, F., Uematsu, K., Byrne, S. D., Hirano, M., Joo-Okumura, A., Nishikimi, A., Shuin, T., Fukui, Y., Nakatsukasa, K. & Kamura, T., 6 1 2016, : : Molecular and cellular biology. 36, 12, p. 1803-1817 15 p.

研究成果: ジャーナルへの寄稿記事

von Hippel-Lindau Disease
Ubiquitin
myb Genes
Platelet-Derived Growth Factor
Pheochromocytoma
3 引用 (Scopus)

Phosphoproteomics analyses show subnetwork systems in T-cell receptor signaling

Hatano, A., Matsumoto, M. & Nakayama, K. I., 10 1 2016, : : Genes to Cells. 21, 10, p. 1095-1112 18 p.

研究成果: ジャーナルへの寄稿記事

Calcineurin
T-Cell Antigen Receptor
Phosphorylation
Mitogen-Activated Protein Kinases
Signal Transduction
4 引用 (Scopus)

Protection of stromal cell-derived factor 2 by heat shock protein 72 prevents oxaliplatin-induced cell death in oxaliplatin-resistant human gastric cancer cells

Takahashi, K., Tanaka, M., Yashiro, M., Matsumoto, M., Ohtsuka, A., Nakayama, K. I., Izumi, Y., Nagayama, K., Miura, K., Iwao, H. & Shiota, M., 8 1 2016, : : Cancer Letters. 378, 1, p. 8-15 8 p.

研究成果: ジャーナルへの寄稿記事

oxaliplatin
HSP72 Heat-Shock Proteins
Stromal Cells
Stomach Neoplasms
Cell Death
7 引用 (Scopus)

PURE mRNA display for in vitro selection of single-chain antibodies

Nagumo, Y., Fujiwara, K., Horisawa, K., Yanagawa, H. & Doi, N., 5 1 2016, : : Journal of biochemistry. 159, 5, p. 519-526 8 p.

研究成果: ジャーナルへの寄稿記事

Single-Chain Antibodies
Display devices
Messenger RNA
Proteins
In Vitro Techniques
1 引用 (Scopus)

Ribophorin ii is involved in the tissue factor expression mediated by phosphatidylserinedependent antiprothrombin antibody on monocytes

Fujieda, Y., Amengual, O., Matsumoto, M., Kuroki, K., Takahashi, H., Kono, M., Kurita, T., Otomo, K., Kato, M., Oku, K., Bohgaki, T., Horita, T., Yasuda, S., Maenaka, K., Hatakeyama, S., Nakayama, K. & Atsumi, T., 6 1 2016, : : Rheumatology (United Kingdom). 55, 6, p. 1117-1126 10 p.

研究成果: ジャーナルへの寄稿記事

Thromboplastin
Prothrombin
Monocytes
Antibodies
Surface Plasmon Resonance
4 引用 (Scopus)

Role of apolipoprotein B100 and oxidized low-density lipoprotein in the monocyte tissue factor induction mediated by anti-β2 glycoprotein i antibodies

Otomo, K., Amengual, O., Fujieda, Y., Nakagawa, H., Kato, M., Oku, K., Horita, T., Yasuda, S., Matsumoto, M., Nakayama, K. I., Hatakeyama, S., Koike, T. & Atsumi, T., 10 1 2016, : : Lupus. 25, 12, p. 1288-1298 11 p.

研究成果: ジャーナルへの寄稿記事

Apolipoproteins
Thromboplastin
Monocytes
Glycoproteins
Antibodies
26 引用 (Scopus)

Suppression of lethal-7b and miR-125a/b Maturation by Lin28b Enables Maintenance of Stem Cell Properties in Hepatoblasts

Takashima, Y., Terada, M., Udono, M., Miura, S., Yamamoto, J. & Suzuki, A., 7 1 2016, : : Hepatology. 64, 1, p. 245-260 16 p.

研究成果: ジャーナルへの寄稿記事

MicroRNAs
Stem Cells
Maintenance
Hepatocytes
Liver
7 引用 (Scopus)

The novel heart-specific RING finger protein 207 is involved in energy metabolism in cardiomyocytes

Mizushima, W., Takahashi, H., Watanabe, M., Kinugawa, S., Matsushima, S., Takada, S., Yokota, T., Furihata, T., Matsumoto, J., Tsuda, M., Chiba, I., Nagashima, S., Yanagi, S., Matsumoto, M., Nakayama, K. I., Tsutsui, H. & Hatakeyama, S., 11 1 2016, : : Journal of Molecular and Cellular Cardiology. 100, p. 43-53 11 p.

研究成果: ジャーナルへの寄稿記事

Cardiac Myocytes
Energy Metabolism
Fingers
Proteins
Heart Failure
14 引用 (Scopus)

The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate

Tortola, L., Nitsch, R., Bertrand, M. J. M., Kogler, M., Redouane, Y., Kozieradzki, I., Uribesalgo, I., Fennell, L. M., Daugaard, M., Klug, H., Wirnsberger, G., Wimmer, R., Perlot, T., Sarao, R., Rao, S., Hanada, T., Takahashi, N., Kernbauer, E., Demiröz, D., Superti-Furga, G. および7人, Decker, T., Pichler, A., Ikeda, F., Kroemer, G., Vandenabeele, P., Sorensen, P. H. & Penninger, J. M., 5 17 2016, : : Cell Reports. 15, 7, p. 1481-1492 12 p.

研究成果: ジャーナルへの寄稿記事

公開
Receptors, Tumor Necrosis Factor, Type I
Tumors
Phosphotransferases
Neoplasms
Ubiquitin-Protein Ligases
22 引用 (Scopus)

Truncation mutants of ASXL1 observed in myeloid malignancies are expressed at detectable protein levels

Inoue, D., Matsumoto, M., Nagase, R., Saika, M., Fujino, T., Nakayama, K. I. & Kitamura, T., 3 1 2016, : : Experimental Hematology. 44, 3, p. 172-176.e1

研究成果: ジャーナルへの寄稿記事

Mutation
Neoplasms
Proteins
Myelodysplastic Syndromes
Hematologic Neoplasms
12 引用 (Scopus)

UV damage-induced phosphorylation of HBO1 triggers CRL4DDB2-mediated degradation to regulate cell proliferation

Matsunuma, R., Niida, H., Ohhata, T., Kitagawa, K., Sakai, S., Uchida, C., Shiotani, B., Matsumoto, M., Nakayama, K. I., Ogura, H., Shiiya, N. & Kitagawa, M., 1 1 2016, : : Molecular and cellular biology. 36, 3, p. 394-406 13 p.

研究成果: ジャーナルへの寄稿記事

Histone Acetyltransferases
Phosphorylation
Cell Proliferation
Replication Origin
DNA Damage
2017
27 引用 (Scopus)

A large-scale targeted proteomics assay resource based on an in vitro human proteome

Matsumoto, M., Matsuzaki, F., Oshikawa, K., Goshima, N., Mori, M., Kawamura, Y., Ogawa, K., Fukuda, E., Nakatsumi, H., Natsume, T., Fukui, K., Horimoto, K., Nagashima, T., Funayama, R., Nakayama, K. & Nakayama, K. I., 2 28 2017, : : Nature Methods. 14, 3, p. 251-258 8 p.

研究成果: ジャーナルへの寄稿記事

Proteome
Proteomics
Assays
Proteins
Monitoring
11 引用 (Scopus)

Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells

Semba, Y., Harada, A., Maehara, K., Oki, S., Meno, C., Ueda, J., Yamagata, K., Suzuki, A., Onimaru, M., Nogami, J., Okada, S., Akashi, K. & Ohkawa, Y., 9 1 2017, : : Nucleic acids research. 45, 15, p. 8758-8772 15 p.

研究成果: ジャーナルへの寄稿記事

DNA Helicases
Embryonic Stem Cells
Chromatin
Gene Expression
Histones
50 引用 (Scopus)

Conversion of Terminally Committed Hepatocytes to Culturable Bipotent Progenitor Cells with Regenerative Capacity

Katsuda, T., Kawamata, M., Hagiwara, K., Takahashi, R. U., Yamamoto, Y., Camargo, F. D. & Ochiya, T., 1 5 2017, : : Cell stem cell. 20, 1, p. 41-55 15 p.

研究成果: ジャーナルへの寄稿記事

Hepatocytes
Stem Cells
Liver
Liver Regeneration
Regenerative Medicine
10 引用 (Scopus)

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells

Muto, Y., Nishiyama, M., Nita, A., Moroishi, T. & Nakayama, K. I., 7 17 2017, : : Nature communications. 8, 16114.

研究成果: ジャーナルへの寄稿記事

homeostasis
stem cells
Hematopoietic Stem Cells
Stem cells
maintenance
7 引用 (Scopus)

FBXL5 inactivation in mouse brain induces aberrant proliferation of neural stem progenitor cells

Yamauchi, T., Nishiyama, M., Moroishi, T., Kawamura, A. & Nakayama, K. I., 4 1 2017, : : Molecular and cellular biology. 37, 8, e00470-16.

研究成果: ジャーナルへの寄稿記事

Neural Stem Cells
Stem Cells
Iron
Iron Regulatory Protein 2
Brain
10 引用 (Scopus)

Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming

Miura, S. & Suzuki, A., 10 5 2017, : : Cell stem cell. 21, 4, p. 456-471.e5

研究成果: ジャーナルへの寄稿記事

Organoids
Cell Lineage
Stem Cells
Intestines
Transcription Factors
13 引用 (Scopus)

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kayama, K., Watanabe, S., Takafuji, T., Tsuji, T., Hironaka, K., Matsumoto, M., Nakayama, K. I., Enari, M., Kohno, T., Shiraishi, K., Kiyono, T., Yoshida, K., Sugimoto, N. & Fujita, M., 1 1 2017, : : EMBO Reports. 18, 1, p. 123-137 15 p.

研究成果: ジャーナルへの寄稿記事

Glutamic Acid
Carcinogenesis
Ligases
Ubiquitin
WD40 Repeats
42 引用 (Scopus)

Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2

Zhang, S., Chen, Q., Liu, Q., Li, Y., Sun, X., Hong, L., Ji, S., Liu, C., Geng, J., Zhang, W., Lu, Z., Yin, Z. Y., Zeng, Y., Lin, K. H., Wu, Q., Li, Q., Nakayama, K., Nakayama, K. I., Deng, X., Johnson, R. L. および4人, Zhu, L., Gao, D., Chen, L. & Zhou, D., 5 8 2017, : : Cancer Cell. 31, 5, p. 669-684.e7

研究成果: ジャーナルへの寄稿記事

Polyploidy
Ploidies
Carcinogenesis
Cyclin-Dependent Kinase Inhibitor p27
Ubiquitin-Protein Ligases

Hypoxia-inducible factor-2α stabilizes the von Hippel-Lindau (VHL) disease suppressor, Mybrelated protein 2

Okumura, F., Joo-Okumura, A., Nakatsukasa, K. & Kamura, T., 4 2017, : : PloS one. 12, 4, e0175593.

研究成果: ジャーナルへの寄稿記事

公開
von Hippel-Lindau Disease
hypoxia
Proteins
proteins
Down-Regulation
1 引用 (Scopus)

In vitro reconstitution of breast cancer heterogeneity with multipotent cancer stem cells using small molecules

Kawamata, M., Katsuda, T., Yamada, Y. & Ochiya, T., 1 22 2017, : : Biochemical and Biophysical Research Communications. 482, 4, p. 750-757 8 p.

研究成果: ジャーナルへの寄稿記事

Multipotent Stem Cells
Neoplastic Stem Cells
Stem cells
Tumors
Breast Neoplasms
152 引用 (Scopus)

MTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide

Matsumoto, A., Pasut, A., Matsumoto, M., Yamashita, R., Fung, J., Monteleone, E., Saghatelian, A., Nakayama, K. I., Clohessy, J. G. & Pandolfi, P. P., 1 12 2017, : : Nature. 541, 7636, p. 228-232 5 p.

研究成果: ジャーナルへの寄稿記事

Long Noncoding RNA
Regeneration
Amino Acids
Muscles
Peptides

mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.

Matsumoto, A., Pasut, A., Matsumoto, M., Yamashita, R., Fung, J., Monteleone, E., Saghatelian, A., Nakayama, K., Clohessy, J. & Pandolfi, P. P., 2017, : : Nature. 541, 7636, p. 228 5 p., 541.

研究成果: ジャーナルへの寄稿記事

Long Noncoding RNA
Regeneration
Amino Acids
Muscles
Peptides
15 引用 (Scopus)

Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages

Nakatsumi, H., Matsumoto, M. & Nakayama, K. I., 11 28 2017, : : Cell Reports. 21, 9, p. 2471-2486 16 p.

研究成果: ジャーナルへの寄稿記事

CC Chemokines
Macrophages
Tumors
Ligands
Neoplasms
10 引用 (Scopus)

NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis

Fukushima, H., Shimizu, K., Watahiki, A., Hoshikawa, S., Kosho, T., Oba, D., Sakano, S., Arakaki, M., Yamada, A., Nagashima, K., Okabe, K., Fukumoto, S., Jimi, E., Bigas, A., Nakayama, K. I., Nakayama, K., Aoki, Y., Wei, W. & Inuzuka, H., 11 16 2017, : : Molecular Cell. 68, 4, p. 645-658.e5

研究成果: ジャーナルへの寄稿記事

Hajdu-Cheney Syndrome
Proteolysis
Osteoporosis
Osteoclasts
Mutation
3 引用 (Scopus)

Sez6l2 regulates phosphorylation of ADD and neuritogenesis

Yaguchi, H., Yabe, I., Takahashi, H., Watanabe, M., Nomura, T., Kano, T., Matsumoto, M., Nakayama, K. I., Watanabe, M. & Hatakeyama, S., 12 9 2017, : : Biochemical and Biophysical Research Communications. 494, 1-2, p. 234-241 8 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Seizures
Glutamate Receptors
Cerebellar Ataxia
Signal transduction
5 引用 (Scopus)

SRRM4-dependent neuron-specific alternative splicing of protrudin transcripts regulates neurite outgrowth

Ohnishi, T., Shirane, M. & Nakayama, K. I., 1 20 2017, : : Scientific reports. 7, 41130.

研究成果: ジャーナルへの寄稿記事

Alternative Splicing
Exons
Neurons
Nervous System
RNA Precursors
16 引用 (Scopus)

Structural basis for the assembly of the Ragulator-Rag GTPase complex

Yonehara, R., Nada, S., Nakai, T., Nakai, M., Kitamura, A., Ogawa, A., Nakatsumi, H., Nakayama, K. I., Li, S., Standley, D. M., Yamashita, E., Nakagawa, A. & Okada, M., 12 1 2017, : : Nature communications. 8, 1, 1625.

研究成果: ジャーナルへの寄稿記事

lysosomes
GTP Phosphohydrolases
assembly
Lysosomes
nutrients
13 引用 (Scopus)

The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis

Shimizu, K., Fukushima, H., Ogura, K., Lien, E. C., Nihira, N. T., Zhang, J., North, B. J., Guo, A., Nagashima, K., Nakagawa, T., Hoshikawa, S., Watahiki, A., Okabe, K., Yamada, A., Toker, A., Asara, J. M., Fukumoto, S., Nakayama, K. I., Nakayama, K., Inuzuka, H. および1人, Wei, W., 1 3 2017, : : Science Signaling. 10, 460

研究成果: ジャーナルへの寄稿記事

Lipogenesis
Ubiquitin-Protein Ligases
Ubiquitination
Sterol Regulatory Element Binding Proteins
Degradation