細胞機能制御学部門

研究成果 1989 2019

フィルター
評論記事
2019
1 引用 (Scopus)

Potentials of C-C motif chemokine 2–C-C chemokine receptor type 2 blockers including propagermanium as anticancer agents

Yumimoto, K., Sugiyama, S., Mimori, K. & Nakayama, K. I., 7 2019, : : Cancer Science. 110, 7, p. 2090-2099 10 p.

研究成果: ジャーナルへの寄稿評論記事

公開
C Chemokines
CC Chemokines
Chemokine Receptors
Antineoplastic Agents
Inflammation
6 引用 (Scopus)

Roles of ubiquitin in autophagy and cell death

Gómez-Díaz, C. & Ikeda, F., 9 2019, : : Seminars in Cell and Developmental Biology. 93, p. 125-135 11 p.

研究成果: ジャーナルへの寄稿評論記事

公開
Autophagy
Ubiquitin
Cell Death
Cell Survival
Garbage
2018
4 引用 (Scopus)

Brief summary of the current protocols for generating intestinal organoids

Miura, S. & Suzuki, A., 8 1 2018, : : Development Growth and Differentiation. 60, 6, p. 387-392 6 p.

研究成果: ジャーナルへの寄稿評論記事

Organoids
Intestinal Diseases
Epithelial Cells
Intestines
Food
4 引用 (Scopus)

Linear ubiquitin chain-binding domains

Fennell, L. M., Rahighi, S. & Ikeda, F., 8 2018, : : FEBS Journal. 285, 15, p. 2746-2761 16 p.

研究成果: ジャーナルへの寄稿評論記事

公開
Ubiquitin
Cell signaling
Autophagy
Cell death
Substrates
5 引用 (Scopus)

The promise of targeted proteomics for quantitative network biology

Matsumoto, M. & Nakayama, K., 12 1 2018, : : Current Opinion in Biotechnology. 54, p. 88-97 10 p.

研究成果: ジャーナルへの寄稿評論記事

Proteomics
Proteins
Assays
Biological Phenomena
Recombinant proteins
2017
1 引用 (Scopus)

Cell fate modification toward the hepatic lineage by extrinsic factors

Kawamata, M. & Suzuki, A., 7 1 2017, : : Journal of Biochemistry. 162, 1, p. 11-16 6 p.

研究成果: ジャーナルへの寄稿評論記事

Stem cells
Liver
Hepatocytes
Induced Pluripotent Stem Cells
Fibroblasts
24 引用 (Scopus)

Linear ubiquitin chains: Enzymes, mechanisms and biology

Rittinger, K. & Ikeda, F., 1 1 2017, : : Open Biology. 7, 4, 170026.

研究成果: ジャーナルへの寄稿評論記事

公開
Ubiquitin
Enzymes
Ubiquitin-Protein Ligases
Polyubiquitin
Mutation
20 引用 (Scopus)

Ubiquitin enzymes in the regulation of immune responses

Ebner, P., Versteeg, G. A. & Ikeda, F., 7 4 2017, : : Critical Reviews in Biochemistry and Molecular Biology. 52, 4, p. 425-460 36 p.

研究成果: ジャーナルへの寄稿評論記事

公開
Ubiquitin
Ubiquitination
Enzymes
Ubiquitin-Protein Ligases
Ubiquitin-Activating Enzymes
2016
35 引用 (Scopus)

To wake up cancer stem cells, or to let them sleep, that is the question

Takeishi, S. & Nakayama, K. I., 7 1 2016, : : Cancer Science. 107, 7, p. 875-881 7 p.

研究成果: ジャーナルへの寄稿評論記事

Neoplastic Stem Cells
Sleep
Cell Cycle
Stem Cell Niche
Therapeutics
2015
6 引用 (Scopus)
Hepatocytes
Liver
Cell Tracking
Cell Lineage
Tamoxifen
4 引用 (Scopus)

MBSJ MCC young scientist award 2012 liver regeneration: A unique and flexible reaction depending on the type of injury

Suzuki, A., 2 1 2015, : : Genes to Cells. 20, 2, p. 77-84 8 p.

研究成果: ジャーナルへの寄稿評論記事

Liver Regeneration
Liver
Wounds and Injuries
Hepatocytes
Living Donors
2014

[Mitochondrial quality control and regulation of neuronal function].

Shirane, M., 2014, : : Seikagaku. The Journal of Japanese Biochemical Society. 86, 4, p. 479-482 4 p.

研究成果: ジャーナルへの寄稿評論記事

Tacrolimus Binding Proteins
Mitochondria
Molecular Chaperones
Neurons
Quality control
7 引用 (Scopus)

Physiological and pathological relevance of secretory microRNAs and a perspective on their clinical application

Katsuda, T., Ikeda, S., Yoshioka, Y., Kosaka, N., Kawamata, M. & Ochiya, T., 4 1 2014, : : Biological chemistry. 395, 4, p. 365-373 9 p.

研究成果: ジャーナルへの寄稿評論記事

MicroRNAs
Physiological Phenomena
Exosomes
Biological Phenomena
Product Packaging
33 引用 (Scopus)

Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells.

Takeishi, S. & Nakayama, K. I., 9 9 2014, : : British journal of cancer. 111, 6, p. 1054-1059 6 p.

研究成果: ジャーナルへの寄稿評論記事

Neoplastic Stem Cells
Maintenance
Cell Cycle
Stem Cells
Neoplasms
18 引用 (Scopus)

Specific and quantitative labeling of biomolecules using click chemistry

Horisawa, K., 1 1 2014, : : Frontiers in Physiology. 5, Nov, 457.

研究成果: ジャーナルへの寄稿評論記事

Click Chemistry
Proteins
Systems Biology
Cross Reactions
Cycloaddition Reaction
2013
5 引用 (Scopus)

Artificial induction and disease-related conversion of the hepatic fate

Suzuki, A., 10 1 2013, : : Current Opinion in Genetics and Development. 23, 5, p. 579-584 6 p.

研究成果: ジャーナルへの寄稿評論記事

Hepatocytes
Liver
Liver Diseases
Transcription Factors
Tissue Transplantation
3 引用 (Scopus)

Integrated view of the human chromosome x-centric proteome project

Yamamoto, T., Nakayama, K., Hirano, H., Tomonaga, T., Ishihama, Y., Yamada, T., Kondo, T., Kodera, Y., Sato, Y., Araki, N., Mamitsuka, H. & Goshima, N., 1 4 2013, : : Journal of Proteome Research. 12, 1, p. 58-61 4 p.

研究成果: ジャーナルへの寄稿評論記事

Human Chromosomes
X Chromosome
Proteome
Chromosomes
Antibodies
15 引用 (Scopus)

Regulation of organogenesis and stem cell properties by T-box transcription factors

Takashima, Y. & Suzuki, A., 10 1 2013, : : Cellular and Molecular Life Sciences. 70, 20, p. 3929-3945 17 p.

研究成果: ジャーナルへの寄稿評論記事

Organogenesis
Transcription Factors
Stem Cells
Induced Pluripotent Stem Cells
Regenerative Medicine
21 引用 (Scopus)

Role of key regulators of the cell cycle in maintenance of hematopoietic stem cells

Matsumoto, A. & Nakayama, K., 2 1 2013, : : Biochimica et Biophysica Acta - General Subjects. 1830, 2, p. 2335-2344 10 p.

研究成果: ジャーナルへの寄稿評論記事

Hematopoietic Stem Cells
Stem cells
Cell Cycle
Cells
Maintenance
2012
1 引用 (Scopus)

Comprehensive study of protein ubiquitylation sites by conjugation of engineered lysine-less ubiquitin

Oshikawa, K., Matsumoto, M. & Nakayama, K., 12 1 2012, : : Seikagaku. 84, 6, p. 479-487 9 p.

研究成果: ジャーナルへの寄稿評論記事

Ubiquitination
Ubiquitin
Lysine
Proteins
1 引用 (Scopus)
Hepatocyte Nuclear Factor 3-gamma
Hepatocyte Nuclear Factor 3-alpha
Hepatocyte Nuclear Factor 6
Hepatocyte Nuclear Factor 3-beta
Tumor Suppressor Proteins
2010
9 引用 (Scopus)

The Musashi family RNA-binding proteins in stem cells

Horisawa, K., Imai, T., Okano, H. & Yanagawa, H., 5 1 2010, : : Biomolecular Concepts. 1, 1, p. 59-66 8 p.

研究成果: ジャーナルへの寄稿評論記事

RNA-Binding Proteins
Stem cells
Stem Cells
Cells
Tissue
2009
8 引用 (Scopus)

Functional similarities and uniqueness of p27 and p57: Insight from a knock-in mouse model

Susaki, E. & Nakayama, K., 8 15 2009, : : Cell Cycle. 8, 16, p. 2497-2501 5 p.

研究成果: ジャーナルへの寄稿評論記事

Cyclin-Dependent Kinases
Cyclin-Dependent Kinase Inhibitor p57
Cyclin-Dependent Kinase Inhibitor p27
Genes
Phenotype
2008
551 引用 (Scopus)

Atypical ubiquitin chains: New molecular signals. 'Protein Modifications: Beyond the Usual Suspects' Review Series

Ikeda, F. & Dikic, I., 6 1 2008, : : EMBO Reports. 9, 6, p. 536-542 7 p.

研究成果: ジャーナルへの寄稿評論記事

公開
Ubiquitin
Proteins
Lysine
Endocytosis
DNA Repair
28 引用 (Scopus)

Fbxw7 in cell cycle exit and stem cell maintenance: Insight from gene-targeted mice

Onoyama, I. & Nakayama, K., 11 1 2008, : : Cell Cycle. 7, 21, p. 3307-3313 7 p.

研究成果: ジャーナルへの寄稿評論記事

Cell Cycle
Stem Cells
Maintenance
Genes
SKP Cullin F-Box Protein Ligases
2 引用 (Scopus)
F-Box Proteins
Proto-Oncogene Proteins c-myc
Tumor Suppressor Protein p53
Cell Cycle Resting Phase
Cell Cycle Proteins

Regulation of cell proliferation and tumorigenesis by ubiquitin-proteasome pathway

Matsumoto, A. & Nakayama, K., 11 1 2008, : : Biotherapy. 22, 6, p. 363-370 8 p.

研究成果: ジャーナルへの寄稿評論記事

Proteasome Endopeptidase Complex
Ubiquitin
Cell Cycle
Carcinogenesis
Cell Proliferation
68 引用 (Scopus)

Signal transduction and transcriptional regulation during mesenchymal cell differentiation

Nishimura, R., Hata, K., Ikeda, F., Ichida, F., Shimoyama, A., Matsubara, T., Wada, M., Amano, K. & Yoneda, T., 5 20 2008, : : Journal of Bone and Mineral Metabolism. 26, 3, p. 203-212 10 p.

研究成果: ジャーナルへの寄稿評論記事

Developmental Gene Expression Regulation
Genetic Transcription
Bone Morphogenetic Proteins
Chondrocytes
Osteoblasts
2007
38 引用 (Scopus)

Multiple mechanisms for p27Kip1 translocation and degradation

Susaki, E. & Nakayama, K., 12 15 2007, : : Cell Cycle. 6, 24, p. 3015-3020 6 p.

研究成果: ジャーナルへの寄稿評論記事

Cyclin D2
Cell Nucleus Active Transport
Cyclin-Dependent Kinases
Growth
Cell Cycle
2006
912 引用 (Scopus)

Ubiquitin ligases: Cell-cycle control and cancer

Nakayama, K. & Nakayama, K., 5 1 2006, : : Nature Reviews Cancer. 6, 5, p. 369-381 13 p.

研究成果: ジャーナルへの寄稿評論記事

Ubiquitination
Ligases
Ubiquitin
Cell Cycle Checkpoints
Cell Cycle
2 引用 (Scopus)

Ubiquitin system regulating G1 and S phases of cell cycle

Nakayama, K. & Nakayama, K., 8 1 2006, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.. 51, 10 Suppl, p. 1362-1369 8 p.

研究成果: ジャーナルへの寄稿評論記事

Ubiquitin-Protein Ligase Complexes
Cyclin-Dependent Kinase Inhibitor Proteins
Cell Cycle Proteins
Cyclin-Dependent Kinases
G1 Phase
2005
8 引用 (Scopus)

Mapping of ubiquitination sites on target proteins

Hatakeyama, S., Matsumoto, M. & Nakayama, K., 1 1 2005, : : Methods in enzymology. 399, p. 277-286 10 p., 19.

研究成果: ジャーナルへの寄稿評論記事

Ubiquitinated Proteins
Ubiquitination
Lysine
Mass Spectrometry
Polyubiquitin
256 引用 (Scopus)

Regulation of the cell cycle by SCF-type ubiquitin ligases

Nakayama, K. & Nakayama, K., 1 1 2005, : : Seminars in Cell and Developmental Biology. 16, 3, p. 323-333 11 p.

研究成果: ジャーナルへの寄稿評論記事

SKP Cullin F-Box Protein Ligases
Cell Cycle
F-Box Proteins
Ubiquitin
Proteolysis
3 引用 (Scopus)

The degradation of p27 and cancer

Kotoshiba, S. & Nakayama, K., 1 1 2005, : : Nippon rinsho. Japanese journal of clinical medicine. 63, 11, p. 2047-2056 10 p.

研究成果: ジャーナルへの寄稿評論記事

Cyclin-Dependent Kinases
Cell Cycle
Cell Cycle Resting Phase
Cyclins
Ubiquitination
2004
5 引用 (Scopus)
Immunophilins
Mitochondria
Apoptosis
Tacrolimus Binding Protein 1A
Apoptosis Regulatory Proteins
2003

Deregulated Proteolysis of the Cell Cycle Regulator p27Kip1 and Cancers

Susaki, E. & Nakayama, K., 11 2003, : : Biotherapy. 17, 6, p. 546-555 10 p.

研究成果: ジャーナルへの寄稿評論記事

Proteolysis
Cell Cycle
Neoplasms
Ubiquitin
S-Phase Kinase-Associated Proteins
217 引用 (Scopus)

Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis

Shirane, M. & Nakayama, K., 1 1 2003, : : Nature Cell Biology. 5, 1, p. 28-37 10 p.

研究成果: ジャーナルへの寄稿評論記事

Tacrolimus Binding Proteins
Mitochondria
Apoptosis
Tacrolimus Binding Protein 1A
Calcineurin
43 引用 (Scopus)

Ubiquitylation as a quality control system for intracellular proteins

Hatakeyama, S. & Nakayama, K. I., 7 1 2003, : : Journal of biochemistry. 134, 1, p. 1-8 8 p.

研究成果: ジャーナルへの寄稿評論記事

Ubiquitination
Quality Control
Quality control
Control systems
Ubiquitin
149 引用 (Scopus)

U-box proteins as a new family of ubiquitin ligases

Hatakeyama, S. & Nakayama, K., 3 21 2003, : : Biochemical and Biophysical Research Communications. 302, 4, p. 635-645 11 p.

研究成果: ジャーナルへの寄稿評論記事

Ligases
Ubiquitin
Fungal Proteins
Fingers
Proteins
2001
189 引用 (Scopus)

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1

Nakayama, K., Hatakeyama, S. & Nakayama, K., 1 1 2001, : : Biochemical and Biophysical Research Communications. 282, 4, p. 853-860 8 p.

研究成果: ジャーナルへの寄稿評論記事

Proteolysis
Cyclin E
Cell Cycle
Cells
Ubiquitin
1998
169 引用 (Scopus)

Cip/Kip cyclin-dependent kinase inhibitors: Brakes of the cell cycle engine during development

Nakayama, K. & Nakayama, K., 1 1 1998, : : BioEssays. 20, 12, p. 1020-1029 10 p.

研究成果: ジャーナルへの寄稿評論記事

Cyclin-Dependent Kinases
Brakes
Cell Cycle
Cells
Engines