応用幹細胞医科学部門

研究成果

年別の研究成果 1992 2015 2016 2017 2018 2019 2020 2021 2023

• 197 学術誌
• 25 総説
• 9 章
• 7 コメント/討論
• 4 その他
  • 2 編集
  • 1 レター
  • 1 簡易調査

年別の研究成果

年別の研究成果

検索結果

• 2023

  Alteration of a Shiga toxin-encoding phage associated with a change in toxin production level and disease severity in Escherichia coli

  Miyata, T., Taniguchi, I., Nakamura, K., Gotoh, Y., Yoshimura, D., Itoh, T., Hirai, S., Yokoyama, E., Ohnishi, M., Iyoda, S., Ogura, Y. & Hayashi, T., 2023, In: Microbial Genomics. 9, 2, 000935.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Phylogenomics 100%

• Complement as a Biomarker for Systemic Lupus Erythematosus

  Ayano, M. & Horiuchi, T., 2月 2023, In: Biomolecules. 13, 2, 367.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  Open Access

  • Systemic Lupus Erythematosus 100%
  • Biological Marker 33%
  • Cells 16%
  • Pathogenesis 16%
  • Marker 16%
• 2022

  Activation of caspase-1 is mediated by stimulation of interferon genes and NLR family pyrin domain containing 3 in monocytes of active systemic lupus erythematosus

  Inokuchi, S., Mitoma, H., Kawano, S., Ayano, M., Kimoto, Y., Akahoshi, M., Arinobu, Y., Akashi, K., Horiuchi, T. & Niiro, H., 2022, In: Clinical and experimental rheumatology. 40, 3, p. 522-531 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Caspase 1 100%
  • Monocyte 80%
  • Systemic Lupus Erythematosus 80%
  • Inflammasome 40%
  • NLR Family Pyrin Domain containing 3 40%
  4 被引用数 (Scopus)

• Controlled X-chromosome dynamics defines meiotic potential of female mouse in vitro germ cells

  Severino, J., Bauer, M., Mattimoe, T., Arecco, N., Cozzuto, L., Lorden, P., Hamada, N., Nosaka, Y., Nagaoka, S. I., Audergon, P., Tarruell, A., Heyn, H., Hayashi, K., Saitou, M. & Payer, B., 6月 14 2022, In: EMBO Journal. 41, 12, e109457.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • X-Inactivation 100%
  • Germ Cell 80%
  • Electric Potential 40%
  • Dynamics 40%
  • Mouse 40%
  2 被引用数 (Scopus)

• Draft Genome Sequences of Five Cystobasidium ongulense Strains Isolated from Areas near Syowa Station, East Antarctica

  Tsuji, M., Ishihara, J. I., Gotoh, Y., Hayashi, T. & Takahashi, H., 7月 2022, In: Microbiology Resource Announcements. 11, 7

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Strains 100%
  • Species 100%
  • Yeast 100%
  • Area 50%
  • Islands 50%
  2 被引用数 (Scopus)

• Dual role of Ovol2 on the germ cell lineage segregation during gastrulation in mouse embryogenesis

  Naitou, Y., Nagamatsu, G., Hamazaki, N., Shirane, K., Hayashi, M., Hayashi, M., Kobayashi, S. & Hayashi, K., 2月 2022, In: Development (Cambridge). 149, 4, dev200319.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Germ Cell 100%
  • Gastrulation 83%
  • Nested Gene 50%
  • Mesenchymal-Epithelial Transition 33%
  • Repressor 33%
  3 被引用数 (Scopus)

• Expression level of the reprogramming factor NeuroD1 is critical for neuronal conversion efficiency from different cell types

  Matsuda-Ito, K., Matsuda, T. & Nakashima, K., 12月 2022, In: Scientific reports. 12, 1, 17980.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Reprogramming 100%
  • Microglia 9%
  • Transcription Factors 9%
  • Somatic Cell 9%
  • Glial Cells 9%
  1 被引用数 (Scopus)

• Factors affecting patient satisfaction related to cost and treatment effectiveness in rheumatoid arthritis: results from the multicenter observational cohort study, FRANK Registry

  Fujiwara, T., Kondo, M., Yamada, H., Haraguchi, A., Fujimura, K., Sakuraba, K., Kamura, S., Fukushi, J-I., Miyahara, H., Inoue, Y., Tsuru, T., Shuto, T., Yoshizawa, S., Suematsu, E., Miyamura, T., Ayano, M., Mitoma, H., Arinobu, Y., Niiro, H., Ohishi, M., & 14 othersHirata, A., Tokunaga, S., Takada, A., Hara, D., Tsushima, H., Akasaki, Y., Ikemura, S., Sueishi, T., Toya, M., Sakuragi, T., Tsutsui, T., Kai, K., Arisumi, S. & Nakashima, Y., 12月 2022, In: Arthritis Research and Therapy. 24, 1, 53.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Patient 100%
  • Satisfaction 90%
  • Health Care Cost 80%
  • Rheumatoid Arthritis 80%
  • Therapeutic Procedure 70%
  2 被引用数 (Scopus)

• Helicobacter cinaedi is a human-adapted lineage in the Helicobacter cinaedi/canicola/‘magdeburgensis’ complex

  Gotoh, Y., Atsuta, Y., Taniguchi, T., Nishida, R., Nakamura, K., Ogura, Y., Misawa, N. & Hayashi, T., 2022, In: Microbial Genomics. 8, 5, 000830.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cladistics 100%
  • Lineages 33%
  • Helicobacter Cinaedi 33%
  • Human 22%
  • Animal 22%
  1 被引用数 (Scopus)

• Hydroxychloroquine versus tacrolimus for the treatment of persistently active systemic lupus erythematosus

  Ayano, M., Kimoto, Y., Mitoma, H., Akahoshi, M., Ono, N., Arinobu, Y., Akashi, K., Horiuchi, T. & Niiro, H., 2月 28 2022, In: Modern Rheumatology. 32, 2, p. 345-350 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Hydroxychloroquine 100%
  • Tacrolimus 83%
  • Disease Activity 83%
  • Lupus Vulgaris 66%
  • Systemic Lupus Erythematosus 50%

• In-vitro maturation and transplantation of cryopreserved ovary tissue: understanding ovarian longevity

  Silber, S. J., Goldsmith, S., Castleman, L., Hurlbut, K., Fan, Y., Melnick, J. & Hayashi, K., 3月 2022, In: Reproductive BioMedicine Online. 44, 3, p. 504-514 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Oocyte 100%
  • In Vitro Maturation 66%
  • Woman 50%
  • Transplantation 50%
  • Ovary 50%
  2 被引用数 (Scopus)

• Naïve-like pluripotency to pave the way for saving the northern white rhinoceros from extinction

  Zywitza, V., Rusha, E., Shaposhnikov, D., Ruiz-Orera, J., Telugu, N., Rishko, V., Hayashi, M., Michel, G., Wittler, L., Stejskal, J., Holtze, S., Göritz, F., Hermes, R., Wang, J., Izsvák, Z., Colleoni, S., Lazzari, G., Galli, C., Hildebrandt, T. B., Hayashi, K., & 2 othersDiecke, S. & Drukker, M., 12月 2022, In: Scientific reports. 12, 1, 3100.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Induced Pluripotent Stem Cell 100%
  • Germ Cell 42%
  • Primordial Germ Cell 42%
  • Gamete 28%
  • Reprogramming 28%
  2 被引用数 (Scopus)

• Omics profiles of fecal and oral microbiota change in irritable bowel syndrome patients with diarrhea and symptom exacerbation

  Tanaka, Y., Yamashita, R., Kawashima, J., Mori, H., Kurokawa, K., Fukuda, S., Gotoh, Y., Nakamura, K., Hayashi, T., Kasahara, Y., Sato, Y. & Fukudo, S., 2022, (印刷中) In: Journal of gastroenterology.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Irritable Bowel Syndrome 100%
  • Symptom 72%
  • Patient 54%
  • Man 18%
  • Diarrhea 18%
  2 被引用数 (Scopus)

• Reconstitution of reproductive organ system that produces functional oocytes

  Hayashi, K. & Yoshino, T., 12月 2022, In: Current Opinion in Genetics and Development. 77, 101982.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  • Germ Cell 100%
  • Reproductive Organ 100%
  • Cell Lineage 66%
  • Cell Maturation 66%
  • Oocyte 66%

• Robust induction of primordial germ cells of white rhinoceros on the brink of extinction

  Hayashi, M., Zywitza, V., Naitou, Y., Hamazaki, N., Goeritz, F., Hermes, R., Holtze, S., Lazzari, G., Galli, C., Stejskal, J., Diecke, S., Hildebrandt, T. B. & Hayashi, K., 2022, In: Science Advances. 8, 49, abp9683.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Germ Cell 100%
  • Whites 70%
  • Rhinoceros 70%
  • Primordial Germ Cell 60%
  • Cells 40%
  1 被引用数 (Scopus)

• Single mutation makes Escherichia coli an insect mutualist

  Koga, R., Moriyama, M., Onodera-Tanifuji, N., Ishii, Y., Takai, H., Mizutani, M., Oguchi, K., Okura, R., Suzuki, S., Gotoh, Y., Hayashi, T., Seki, M., Suzuki, Y., Nishide, Y., Hosokawa, T., Wakamoto, Y., Furusawa, C. & Fukatsu, T., 8月 2022, In: Nature Microbiology. 7, 8, p. 1141-1150 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Escherichia coli 100%
  • Mutation 44%
  • Insect 44%
  • Insecta 44%
  • Symbiosis 33%
  4 被引用数 (Scopus)

• The people behind the papers - Yuki Naitou and Katsuhiko Hayashi

  Naitou, Y. & Hayashi, K., 2月 2022, In: Development (Cambridge). 149, 4, 200544.

  研究成果: ジャーナルへの寄稿 › コメント/討論 › 査読

  Open Access

• TNFR2 Signaling Enhances Suppressive Abilities of Human Circulating T Follicular Regulatory Cells

  Kawano, S., Mitoma, H., Inokuchi, S., Yamauchi, Y., Yokoyama, K., Nogami, J., Semba, Y., Ayano, M., Kimoto, Y., Akahoshi, M., Ono, N., Arinobu, Y., Akashi, K., Horiuchi, T. & Niiro, H., 3月 1 2022, In: Journal of immunology (Baltimore, Md. : 1950). 208, 5, p. 1057-1065 9 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Regulatory Cell 100%
  • B Cell 19%
  • Cell Proliferation 15%
  • Germinal Center 11%
  • Inflammatory Disorder 11%
  1 被引用数 (Scopus)

• Year-round dynamics of amplicon sequence variant communities differ among eukaryotes, Imitervirales and prokaryotes in a coastal ecosystem

  Prodinger, F., Endo, H., Takano, Y., Li, Y., Tominaga, K., Isozaki, T., Blanc-Mathieu, R., Gotoh, Y., Hayashi, T., Taniguchi, E., Nagasaki, K., Yoshida, T. & Ogata, H., 1月 8 2022, In: FEMS microbiology ecology. 97, 12

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Eukaryote 100%
  • Prokaryote 75%
  • Amplicon 75%
  • Community Dynamics 37%
  • Dynamics 25%
  3 被引用数 (Scopus)
• 2021

  Artificially produced gametes in mice, humans and other species

  Hayashi, K., Galli, C., Diecke, S. & Hildebrandt, T. B., 1月 8 2021, In: Reproduction, Fertility and Development. 33, 2, p. 91-101 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Germ Cell 100%
  • Mice 83%
  • Mouse 83%
  • Species 66%
  • Egg Cell 66%
  4 被引用数 (Scopus)

• Association of elevated serum soluble CD226 levels with the disease activity and flares of systemic lupus erythematosus

  Nakano, M., Ayano, M., Kushimoto, K., Kawano, S., Higashioka, K., Inokuchi, S., Mitoma, H., Kimoto, Y., Akahoshi, M., Ono, N., Arinobu, Y., Akashi, K., Horiuchi, T. & Niiro, H., 12月 2021, In: Scientific reports. 11, 1, 16162.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • CD226 100%
  • Systemic Lupus Erythematosus 91%
  • Association 16%
  • T Cell 16%
  • Cell Surface 8%
  1 被引用数 (Scopus)

• Autoimmune manifestations associated with myelodysplastic syndrome predict a poor prognosis

  Arinobu, Y., Kashiwado, Y., Miyawaki, K., Ayano, M., Kimoto, Y., Mitoma, H., Akahoshi, M., Miyamoto, T., Horiuchi, T., Akashi, K. & Niiro, H., 4月 2 2021, In: Medicine. 100, 13, p. e25406

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Myelodysplastic Syndrome 100%
  • Scoring System 40%
  • Patient 30%
  • Diagnosis 20%
  • Prognosis 20%
  8 被引用数 (Scopus)

• CADM1 and CADM2 trigger neuropathogenic measles virus-mediated membrane fusion by acting in cis

  Shirogane, Y., Takemoto, R., Suzuki, T., Kameda, T., Nakashima, K., Hashiguchi, T. & Yanagi, Y., 7月 2021, In: Journal of virology. 95, 14, e00528.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Measles Virus 100%
  • Neuron 93%
  • Brain 53%
  • Cell Adhesion Molecule 1 46%
  • Eicosanoid Receptor 46%
  7 被引用数 (Scopus)

• "Candidatus Mesenet longicola": Novel Endosymbionts of Brontispa longissima that Induce Cytoplasmic Incompatibility

  Takano, S-I., Gotoh, Y. & Hayashi, T., 1月 16 2021, (印刷前の電子出版) In: Microbial Ecology.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cytoplasmic Incompatibility 100%
  • Symbion 57%
  • Bacteria 28%
  • Cladistics 28%
  • Brontispa longissima 28%

• Clarifying the ability of NeuroD1 to convert mouse microglia into neurons

  Matsuda, T. & Nakashima, K., 12月 15 2021, In: Neuron. 109, 24, p. 3912-3913 2 p.

  研究成果: ジャーナルへの寄稿 › レター › 査読
  5 被引用数 (Scopus)

• Combinatrial treatment of anti-High Mobility Group Box-1 monoclonal antibody and epothilone B improves functional recovery after spinal cord contusion injury

  Zhu, Y., Uezono, N., Yasui, T., Nakajo, M., Nagai, T., Wang, D., Nishibori, M. & Nakashima, K., 11月 2021, In: Neuroscience Research. 172, p. 13-25 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Monoclonal Antibody 100%
  • High-Mobility Group 100%
  • Epothilone 71%
  • Epothilone B 71%
  • Therapeutic Procedure 57%
  5 被引用数 (Scopus)

• Comparative genomic and physiological analysis against clostridium scindens reveals eubacterium sp. C-25 as an atypical deoxycholic acid producer of the human gut microbiota

  Song, I., Gotoh, Y., Ogura, Y., Hayashi, T., Fukiya, S. & Yokota, A., 11月 2021, In: Microorganisms. 9, 11, 2254.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Bile Acid 100%
  • Deoxycholic Acid 100%
  • Humans 50%
  • Eubacterium 37%
  • Nested Gene 25%
  2 被引用数 (Scopus)

• Decreased Lamin B1 Levels Affect Gene Positioning and Expression in Postmitotic Neurons

  Noguchi, A., Ito, K., Uosaki, Y., Ideta-Otsuka, M., Igarashi, K., Nakashima, H., Kakizaki, T., Kaneda, R., Uosaki, H., Yanagawa, Y., Nakashima, K., Arakawa, H. & Takizawa, T., 12月 2021, In: Neuroscience Research. 173, p. 22-33 12 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Neuron 100%
  • Maturation 80%
  • Lamin 80%
  • Nested Gene 60%
  • Gene 60%
  3 被引用数 (Scopus)

• Diversification of Escherichia albertii H-Antigens and Development of H-Genotyping PCR

  Nakae, K., Ooka, T., Murakami, K., Hara-Kudo, Y., Imuta, N., Gotoh, Y., Ogura, Y., Hayashi, T., Okamoto, Y. & Nishi, J., 11月 1 2021, In: Frontiers in Microbiology. 12, 737979.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Genotype 100%
  • Gene 62%
  • Escherichia coli 37%
  • H Antigen 37%
  • Polymerase Chain Reaction 25%
  2 被引用数 (Scopus)

• Draft genome sequence of medusavirus stheno, isolated from the tatakai river of Uji, Japan

  Yoshida, K., Zhang, R., Garcia, K. G., Endo, H., Gotoh, Y., Hayashi, T., Takemura, M. & Ogata, H., 1月 7 2021, In: Microbiology Resource Announcements. 10, 1, e0132320.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Genome Sequencing 100%
  • Sample 100%
  • Virus 100%
  • Coculture 100%
  • Double-Stranded DNA Virus 100%
  8 被引用数 (Scopus)

• d-Tryptophan enhances the reproductive organ-specific expression of the amino acid transporter homolog Dr-SLC38A9 involved in the sexual induction of planarian Dugesia ryukyuensis

  Maezawa, T., Ishikawa, M., Sekii, K., Nagamatsu, G., Furukawa, R. & Kobayashi, K., 12月 2021, In: Zoological Letters. 7, 1, 4.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Planarian 100%
  • Worm 60%
  • Reproductive Organ 60%
  • Development 40%
  • RNA Interference 40%
  1 被引用数 (Scopus)

• Early-life midazolam exposure persistently changes chromatin accessibility to impair adult hippocampal neurogenesis and cognition

  Doi, H., Matsuda, T., Sakai, A., Matsubara, S., Hoka, S., Yamaura, K. & Nakashima, K., 9月 21 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 38, e2107596118.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Midazolam 100%
  • Life 75%
  • Neurogenesis 75%
  • Neural Stem Cell 50%
  • Chromatin 50%
  4 被引用数 (Scopus)

• Generation of ovarian follicles from mouse pluripotent stem cells

  Yoshino, T., Suzuki, T., Nagamatsu, G., Yabukami, H., Ikegaya, M., Kishima, M., Kita, H., Imamura, T., Nakashima, K., Nishinakamura, R., Tachibana, M., Inoue, M., Shima, Y., Morohashi, K. I. & Hayashi, K., 7月 16 2021, In: Science. 373, 6552, eabe0237.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Cells 100%
  • Oocyte 83%
  • Somatics 33%
  • Culture 33%
  • Meiosis 33%
  42 被引用数 (Scopus)

• Growth factors with valproic acid restore injury-impaired hearing by promoting neuronal regeneration

  Wakizono, T., Nakashima, H., Yasui, T., Noda, T., Aoyagi, K., Okada, K., Yamada, Y., Nakagawa, T. & Nakashima, K., 11月 22 2021, In: JCI Insight. 6, 22, e139171.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Neuron 100%
  • Spiral Ganglion 33%
  • Injury 16%
  • Sensorineural Hearing Loss 16%
  • Sensation of Hearing 16%
  4 被引用数 (Scopus)

• HLA-B52 allele in giant cell arteritis may indicate diffuse large-vessel vasculitis formation: a retrospective study

  Kushimoto, K., Ayano, M., Nishimura, K., Nakano, M., Kimoto, Y., Mitoma, H., Ono, N., Arinobu, Y., Akashi, K., Horiuchi, T. & Niiro, H., 12月 2021, In: Arthritis Research and Therapy. 23, 1, 238.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Vasculitis 100%
  • Patient 84%
  • Human Leukocyte Antigen 69%
  • Giant-Cell Arteritis 53%
  • Giant Cell Arteritis 53%
  1 被引用数 (Scopus)

• Human PD-1^hiCD8⁺ T Cells Are a Cellular Source of IL-21 in Rheumatoid Arthritis

  Higashioka, K., Yoshimura, M., Sakuragi, T., Ayano, M., Kimoto, Y., Mitoma, H., Ono, N., Arinobu, Y., Kikukawa, M., Yamada, H., Horiuchi, T., Akashi, K. & Niiro, H., 3月 19 2021, In: Frontiers in Immunology. 12, 654623.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Cytotoxic T-Cell 100%
  • Inflammatory Arthritis 50%
  • Rheumatoid Arthritis 50%
  • T Cell 41%
  • T-Helper Cell 33%
  9 被引用数 (Scopus)

• Increased Proportion of CD226⁺ B Cells Is Associated With the Disease Activity and Prognosis of Systemic Lupus Erythematosus

  Nakano, M., Ayano, M., Kushimoto, K., Kawano, S., Higashioka, K., Inokuchi, S., Mitoma, H., Kimoto, Y., Akahoshi, M., Ono, N., Arinobu, Y., Akashi, K., Horiuchi, T. & Niiro, H., 7月 21 2021, In: Frontiers in Immunology. 12, 713225.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • CD226 100%
  • B Cell 81%
  • Systemic Lupus Erythematosus 62%
  • Patient 18%
  • Inpatient 18%
  1 被引用数 (Scopus)

• Infliximab for reversible dementia in acute onset of neuro-Behçet's disease: A case report and cytokine analysis

  Imabayashi, K., Ayano, M., Higashioka, K., Yokoyama, K., Yamamoto, K., Takayama, K., Mitoma, H., Kimoto, Y., Akahoshi, M., Arinobu, Y., Akashi, K., Horiuchi, T. & Niiro, H., 8月 15 2021, In: Journal of Neuroimmunology. 357, 577631.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Infliximab 100%
  • Dementia 75%
  • Glucocorticoid 50%
  • Brain 25%
  • Antibodies 25%
  1 被引用数 (Scopus)

• In vivo direct reprogramming as a therapeutic strategy for brain and retina repair

  Sekiryu, H. & Matsuda, T., 10月 2021, In: Neural Regeneration Research. 16, 10, p. 1998-1999 2 p.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  Open Access
  3 被引用数 (Scopus)

• Mammalian in vitro gametogenesis

  Saitou, M. & Hayashi, K., 10月 1 2021, In: Science. 374, 6563, aaz6830.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  • Germ Cell 100%
  • In Vitro 75%
  • Cell Maturation 75%
  • Oocyte 75%
  • Egg Cell 75%
  25 被引用数 (Scopus)

• MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling

  Nakashima, H., Tsujimura, K., Irie, K., Imamura, T., Trujillo, C. A., Ishizu, M., Uesaka, M., Pan, M., Noguchi, H., Okada, K., Aoyagi, K., Andoh-Noda, T., Okano, H., Muotri, A. R. & Nakashima, K., 5月 18 2021, In: Cell Reports. 35, 7, 109124.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Rett Syndrome 100%
  • Bone Morphogenetic Protein 80%
  • Brain Development 40%
  • Development 20%
  • Electric Potential 20%
  10 被引用数 (Scopus)

• Metagenomic analysis of gut microbiota reveals its role in trimethylamine metabolism in heart failure

  Emoto, T., Hayashi, T., Tabata, T., Yamashita, T., Watanabe, H., Takahashi, T., Gotoh, Y., Kami, K., Yoshida, N., Saito, Y., Tanaka, H., Matsumoto, K., Hayashi, T., Yamada, T. & Hirata, K. I., 9月 1 2021, In: International Journal of Cardiology. 338, p. 138-142 5 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Trimethylamine N-Oxide 100%
  • Intestine Flora 66%
  • Choline 33%
  • Metagenome 33%
  • Metabolic Pathway 16%
  4 被引用数 (Scopus)

• Natural and forced neurogenesis in the adult brain: Mechanisms and their possible application to treat neurological disorders

  Matsuda, T. & Nakashima, K., 5月 2021, In: Neuroscience Research. 166, p. 1-11 11 p.

  研究成果: ジャーナルへの寄稿 › 総説 › 査読

  • Neurogenesis 100%
  • Nervous System Development 100%
  • Brain 62%
  • Neuron 37%
  • Neural Stem Cell 37%
  5 被引用数 (Scopus)

• Neural stem/precursor cells dynamically change their epigenetic landscape to differentially respond to BMP signaling for fate switching during brain development

  Katada, S., Takouda, J., Nakagawa, T., Honda, M., Igarashi, K., Imamura, T., Ohkawa, Y., Sato, S., Kurumizaka, H. & Nakashima, K., 11月 1 2021, In: Genes and Development. 35, 21-22, p. 1431-1444 14 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • Precursor 100%
  • Regulatory Mechanism 42%
  • Bone Morphogenetic Protein 42%
  • Development 28%
  • Binding Site 28%
  3 被引用数 (Scopus)

• Neuronal activation modulates enhancer activity of genes for excitatory synaptogenesis through de novo DNA methylation

  Kameda, T., Nakashima, H., Takizawa, T., Miura, F., Ito, T., Nakashima, K. & Imamura, T., 2021, In: Journal of Reproduction and Development. 67, 6, p. 369-379 11 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  Open Access

  • DNA Methylation 100%
  • Neuronal Activity 75%
  • Nested Gene 37%
  • Enhancer Region 37%
  • Synaptogenesis 37%

• Outcomes of methotrexate-associated lymphoproliferative disorders in rheumatoid arthritis patients treated with disease-modifying anti-rheumatic drugs

  Harada, T., Iwasaki, H., Muta, T., Urata, S., Sakamoto, A., Kohno, K., Takase, K., Miyamura, T., Sawabe, T., Asaoku, H., Oryoji, K., Fujisaki, T., Mori, Y., Yoshimoto, G., Ayano, M., Mitoma, H., Miyamoto, T., Niiro, H., Yamamoto, H., Oshiro, Y., & 5 othersMiyoshi, H., Ohshima, K., Takeshita, M., Akashi, K. & Kato, K., 7月 2021, In: British Journal of Haematology. 194, 1, p. 101-110 10 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Methotrexate 100%
  • Patient 62%
  • Rheumatoid Arthritis 62%
  • Inflammatory Arthritis 62%
  • Disease Modifying Antirheumatic Drug 50%
  2 被引用数 (Scopus)

• Pan-PI3Ki targets multiple B-ALL microenvironment interactions that fuel systemic and CNS relapse

  Ridge, S. M., Whiteley, A. E., Yao, H., Price, T. T., Brockman, M. L., Murray, A. S., Simon, B. G., Islam, P. & Sipkins, D. A., 2021, In: Leukemia and Lymphoma. 62, 11, p. 2690-2702 13 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Acute Lymphoblastic Leukemia 100%
  • Central Nervous System 83%
  • Systemic Disease 50%
  • Relapse 33%
  • Survival 33%
  1 被引用数 (Scopus)

• Paternal MTHFR deficiency leads to hypomethylation of young retrotransposons and reproductive decline across two successive generations

  Karahan, G., Chan, D., Shirane, K., McClatchie, T., Janssen, S., Baltz, J. M., Lorincz, M. & Trasler, J., 6月 15 2021, (印刷前の電子出版) In: Development (Cambridge, England).

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Methylenetetrahydrofolate Reductase 100%
  • 5,10-Methylenetetrahydrofolate 100%
  • DNA Methylation 57%
  • Retrotransposon 42%
  • Germ Cell 28%
  7 被引用数 (Scopus)

• Predictive factors of fetal and maternal pregnancy outcomes in Japanese patients with systemic lupus erythematosus

  Irino, K., Arinobu, Y., Ayano, M., Kawano, S., Kimoto, Y., Mitoma, H., Akahoshi, M., Akashi, K., Horiuchi, T. & Niiro, H., 9月 2021, In: Lupus. 30, 10, p. 1637-1643 7 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Pregnancy 100%
  • Lupus Erythematosus 50%
  • Systemic Lupus Erythematosus 35%
  • Birth 14%
  • Immunosuppressive Drug 14%
  1 被引用数 (Scopus)

• Reconstitution of the oocyte transcriptional network with transcription factors

  Hamazaki, N., Kyogoku, H., Araki, H., Miura, F., Horikawa, C., Hamada, N., Shimamoto, S., Hikabe, O., Nakashima, K., Kitajima, T. S., Ito, T., Leitch, H. G. & Hayashi, K., 1月 14 2021, In: Nature. 589, 7841, p. 264-269 6 p.

  研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

  • Oocyte Development 100%
  • Oogenesis 100%
  • Transcription Factor 85%
  • Oocyte 42%
  • Cells 28%
  52 被引用数 (Scopus)