研究成果

2019

Ammonium Salt-Accelerated Hydrazinolysis of Unactivated Amides: Mechanistic Investigation and Application to a Microwave Flow Process

Noshita, M., Shimizu, Y., Morimoto, H., Akai, S., Hamashima, Y., Ohneda, N., Odajima, H. & Ohshima, T., 4 19 2019, : : Organic Process Research and Development. 23, 4, p. 588-594 7 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

A new approach to prevent the chemotherapy-induced peripheral neuropathy

Kawashiri, T., 1 1 2019, : : Folia Pharmacologica Japonica. 153, 4, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

An indirect competitive enzyme-linked immunosorbent assay toward the standardization of Pueraria candollei based on its unique isoflavonoid, kwakhurin

Yusakul, G., Togita, R., Minami, K., Chanpokapaiboon, K., Juengwatanatrakul, T., Putalun, W., Tanaka, H., Sakamoto, S. & Morimoto, S., 3 2019, : : Fitoterapia. 133, p. 23-28 6 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

A novel mode of DnaA-DnaA interaction promotes ADP dissociation for reactivation of replication initiation activity

Sugiyama, R., Kasho, K., Miyoshi, K., Ozaki, S., Kagawa, W., Kurumizaka, H. & Katayama, T., 12 2 2019, : : Nucleic acids research. 47, 21, p. 11209-11224 16 p.

研究成果: ジャーナルへの寄稿記事

公開

Anti-allergic activity of polyphenolic compounds isolated from olive mill wastes

Mwakalukwa, R., Ashour, A., Amen, Y., Niwa, Y., Tamrakar, S., Miyamoto, T. & Shimizu, K., 7 1 2019, : : Journal of Functional Foods. 58, p. 207-217 11 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Ascorbic acid insufficiency impairs spatial memory formation in juvenile AKR1A-knockout mice

Kurihara, K., Homma, T., Kobayashi, S., Shichiri, M., Fujiwara, H., Fujii, S., Yamada, K., Nakane, M., Kawamae, K. & Fujii, J., 1 1 2019, : : Journal of Clinical Biochemistry and Nutrition. 65, 3, p. 209-216 8 p.

研究成果: ジャーナルへの寄稿記事

Characterization of α-synuclein N-terminal domain as a novel cellular phosphatidic acid sensor

Yamada, H., Mizuno, S., Honda, S., Takahashi, D. & Sakane, F., 1 1 2019, (受理済み/印刷中) : : FEBS Journal.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Chronopharmacological strategies focused on chrono-drug discovery

Ohdo, S., Koyanagi, S. & Matsunaga, N., 10 2019, : : Pharmacology and Therapeutics. 202, p. 72-90 19 p.

研究成果: ジャーナルへの寄稿評論記事

1 引用 (Scopus)

Circulating messenger for neuroprotection induced by molecular hydrogen

Noda, M., Uemura, Y., Yoshii, Y., Horita, T., Takemi, S., Sakata, I. & Sakai, T., 1 1 2019, : : Canadian journal of physiology and pharmacology. 97, 10, p. 909-915 7 p.

研究成果: ジャーナルへの寄稿評論記事

1 引用 (Scopus)

Clinical Pharmacokinetics of Anaplastic Lymphoma Kinase Inhibitors in Non-Small-Cell Lung Cancer

Hirota, T., Muraki, S. & Ieiri, I., 4 4 2019, : : Clinical Pharmacokinetics. 58, 4, p. 403-420 18 p.

研究成果: ジャーナルへの寄稿評論記事

6 引用 (Scopus)

Crystal structure and calcium-induced conformational changes of diacylglycerol kinase α EF-hand domains

Takahashi, D., Suzuki, K., Sakamoto, T., Iwamoto, T., Murata, T. & Sakane, F., 4 2019, : : Protein Science. 28, 4, p. 694-706 13 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level

Kataoka, Y., Iimori, M., Niimi, S., Tsukihara, H., Wakasa, T., Saeki, H., Oki, E., Maehara, Y. & Kitao, H., 12 1 2019, : : Scientific reports. 9, 1, 7964.

研究成果: ジャーナルへの寄稿記事

公開
2 引用 (Scopus)

Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload

Nishimura, A., Shimoda, K., Tanaka, T., Toyama, T., Nishiyama, K., Shinkai, Y., Numaga-Tomita, T., Yamazaki, D., Kanda, Y., Akaike, T., Kumagai, Y. & Nishida, M., 1 1 2019, : : Science Signaling. 12, 587, eaaw1920.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Development of a simple and rapid method for the detection of isomiroestrol in Pueraria candollei by an immunochromatographic strip test

Chaingam, J., Kitisripanya, T., Krittanai, S., Sakamoto, S., Tanaka, H. & Putalun, W., 6 14 2019, : : Journal of Natural Medicines. 73, 3, p. 577-583 7 p.

研究成果: ジャーナルへの寄稿記事

Development of novel functional molecules targeting DNA and RNA

Sasaki, S., 1 1 2019, : : Chemical and Pharmaceutical Bulletin. 67, 6, p. 505-518 14 p.

研究成果: ジャーナルへの寄稿評論記事

公開

Development of Turn-On Probes for Acids Triggered by Aromaticity Enhancement Using Tricyclic Amidine Derivatives

Matsumoto, S., Fuchi, Y., Usui, K., Hirai, G. & Karasawa, S., 6 7 2019, : : Journal of Organic Chemistry. 84, 11, p. 6612-6622 11 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Diacylglycerol kinase α-selective inhibitors induce apoptosis and reduce viability of melanoma and several other cancer cell lines

Yamaki, A., Akiyama, R., Murakami, C., Takao, S., Murakami, Y., Mizuno, S., Takahashi, D., Kado, S., Taketomi, A., Shirai, Y., Goto, K. & Sakane, F., 6 2019, : : Journal of Cellular Biochemistry. 120, 6, p. 10043-10056 14 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)
公開
2 引用 (Scopus)

Donepezil ameliorates oxaliplatin-induced peripheral neuropathy via a neuroprotective effect

kawashiri, T., Shimizu, S., Shigematsu, N., Kobayashi, D. & Shimazoe, T., 7 1 2019, : : Journal of Pharmacological Sciences. 140, 3, p. 291-294 4 p.

研究成果: ジャーナルへの寄稿記事

公開
1 引用 (Scopus)

Dosing Time-Dependent Changes in the Anti-tumor Effect of xCT Inhibitor Erastin in Human Breast Cancer Xenograft Mice

Shiromizu, S., Yamauchi, T., Kusunose, N., Matsunaga, N., Koyanagi, S. & Ohdo, S., 1 1 2019, : : Biological and Pharmaceutical Bulletin. 42, 11, p. 1921-1925 5 p.

研究成果: ジャーナルへの寄稿記事

公開
1 引用 (Scopus)

D -Serine reflects kidney function and diseases

Hesaka, A., Sakai, S., Hamase, K., Ikeda, T., Matsui, R., Mita, M., Horio, M., Isaka, Y. & Kimura, T., 12 1 2019, : : Scientific reports. 9, 1, 5104.

研究成果: ジャーナルへの寄稿記事

公開
5 引用 (Scopus)

Effect of digital labels on electronic medical records for reducing the use of benzodiazepine receptor agonists

Shin, K., Kobayashi, D., Kawashiri, T., Ikari, K., Mitsuyasu, H., Murakami, T., Tsutsumi, K., Kanazawa, Y., Kamimura, H. & Shimazoe, T., 1 1 2019, : : Yakugaku Zasshi. 139, 11, p. 1449-1456 8 p.

研究成果: ジャーナルへの寄稿記事

公開

Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers

Mori, D., Kashihara, Y., Yoshikado, T., Kimura, M., Hirota, T., Matsuki, S., Maeda, K., Irie, S., Ieiri, I., Sugiyama, Y. & Kusuhara, H., 2 2019, : : Drug metabolism and pharmacokinetics. 34, 1, p. 78-86 9 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation

Kashihara, Y., Terao, Y., Yoda, K., Hirota, T., Kubota, T., Kimura, M., Matsuki, S., Hirakawa, M., Irie, S. & Ieiri, I., 3 6 2019, : : European Journal of Clinical Pharmacology. 75, 3, p. 351-361 11 p.

研究成果: ジャーナルへの寄稿記事

Effects of Substituents on the Properties of Metal-Free MRI Contrast Agents

Shiraishi, R., Kaneko, T., Usui, K., Naganuma, T., Iizuka, N., Morishita, K., Kobayashi, S., Fuchi, Y., Matsuoka, Y., Hirai, G., Yamada, K. I. & Karasawa, S., 12 10 2019, : : ACS Omega. 4, 24, p. 20715-20723 9 p.

研究成果: ジャーナルへの寄稿記事

公開

Effects of the 2-substituted adenosine-1,3-diazaphenoxazine 5′-triphosphate derivatives on the single nucleotide primer extension reaction by DNA polymerase

Taniguchi, Y., Sagara, I., Nagata, Y., Kikukawa, Y. & Sasaki, S., 1 1 2019, : : Chemical and Pharmaceutical Bulletin. 67, 10, p. 1123-1130 8 p.

研究成果: ジャーナルへの寄稿記事

公開

Efficacy of DPP-4 inhibitors, GLP-1 analogues, and SGLT2 inhibitors as add-ons to metformin monotherapy in T2DM patients: a model-based meta-analysis

Inoue, H., Tamaki, Y., Kashihara, Y., Muraki, S., Kakara, M., Hirota, T. & Ieiri, I., 2 2019, : : British journal of clinical pharmacology. 85, 2, p. 393-402 10 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Electron Microscopic Detection of Single Membrane Proteins by a Specific Chemical Labeling

Tabata, S., Jevtic, M., Kurashige, N., Fuchida, H., Kido, M., Tani, K., Zenmyo, N., Uchinomiya, S., Harada, H., Itakura, M., Hamachi, I., Shigemoto, R. & Ojida, A., 12 20 2019, : : iScience. 22, p. 256-268 13 p.

研究成果: ジャーナルへの寄稿記事

公開

Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory

Li, R. S., Fukumori, R., Takeda, T., Song, Y., Morimoto, S., Kikura-Hanajiri, R., Yamaguchi, T., Watanabe, K., Aritake, K., Tanaka, Y., Yamada, H., Yamamoto, T. & Ishii, Y., 7 3 2019, : : Scientific reports. 9, 1, 1 p., 9621.

研究成果: ジャーナルへの寄稿記事

公開

Elucidation of N1-methyladenosine as a potential surrogate biomarker for drug interaction studies involving renal organic cation transporters

Miyake, T., Mizuno, T., Takehara, I., Mochizuki, T., Kimura, M., Matsuki, S., Irie, S., Watanabe, N., Kato, Y., Ieiri, I., Maeda, K., Ando, O. & Kusuhara, H., 1 1 2019, : : Drug Metabolism and Disposition. 47, 11, p. 1270-1280 11 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Enhancement of saccharothriolide production and discovery of a new metabolite, saccharothriolide C 2 , by combined-culture of Saccharothrix sp. and Tsukamurella pulmonis

Jiang, Y., Lu, S., Hirai, G., Kato, T., Onaka, H. & Kakeya, H., 4 11 2019, : : Tetrahedron Letters. 60, 15, p. 1072-1074 3 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)
公開
2 引用 (Scopus)

Estradiol regulation of P-glycoprotein expression in mouse kidney and human tubular epithelial cells, implication for renal clearance of drugs

Kanado, Y., Tsurudome, Y., Omata, Y., Yasukochi, S., Kusunose, N., Akamine, T., Matsunaga, N., Koyanagi, S. & Ohdo, S., 11 12 2019, : : Biochemical and Biophysical Research Communications. 519, 3, p. 613-619 7 p.

研究成果: ジャーナルへの寄稿記事

Evaluation of pharmacist-led interview before doctor examination for psychiatry outpatients

Shin, K., Kobayashi, D., kawashiri, T., Ushijima, Y., Umeda, Y., Kanazawa, Y., Kamimura, H. & Shimazoe, T., 1 1 2019, : : Yakugaku Zasshi. 139, 2, p. 317-325 9 p.

研究成果: ジャーナルへの寄稿コメント/討論

Evaluation of the immunomodulatory effects of fucoidan derived from cladosiphon okamuranus tokida in mice

Tomori, M., Nagamine, T., Miyamoto, T. & Iha, M., 9 24 2019, : : Marine Drugs. 17, 10, 547.

研究成果: ジャーナルへの寄稿記事

公開
2 引用 (Scopus)

Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure

Igawa, T., Kishikawa, S., Abe, Y., Yamashita, T., Nagai, S., Shiroishi, M., Shinozaki, C., Tanaka, H., Tozaki-Saitoh, H., Tsuda, M., Inoue, K. & Ueda, T., 3 15 2019, : : Purinergic Signalling. 15, 1, p. 27-35 9 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Expression, Purification, and Characterization of Human Diacylglycerol Kinase ζ

Saito, T., Takahashi, D. & Sakane, F., 3 19 2019, : : ACS Omega. 4, 3, p. 5540-5546 7 p.

研究成果: ジャーナルへの寄稿記事

公開
1 引用 (Scopus)

Hederagenin glycosides from the fruits of Blighia unijugata

Petit, B., Mitaine-Offer, A. C., Delaude, C., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., 6 1 2019, : : Phytochemistry. 162, p. 260-269 10 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome

Yasui, M., Menjyo, Y., Tokizane, K., Shiozawa, A., Tsuda, M., Inoue, K. & Kiyama, H., 3 30 2019, : : Journal of neuroinflammation. 16, 1, 67.

研究成果: ジャーナルへの寄稿記事

公開

Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes

Nishiyama, K., Numaga-Tomita, T., Fujimoto, Y., Tanaka, T., Toyama, C., Nishimura, A., Yamashita, T., Naoya, M., Satoru, K., Azuma, Y. T., Ibuki, Y., Uchida, K., Ohdo, S. & Nishida, M., 9 1 2019, : : British Journal of Pharmacology. 176, 18, p. 3723-3738 16 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10

Yokoyama, T., Yukuhiro, M., Iwasaki, Y., Tanaka, C., Sankoda, K., Fujiwara, R., Shibuta, A., Higashi, T., Motoyama, K., Arima, H., Yoshida, K., Sugimoto, N., Morimoto, H., Kosako, H., Ohshima, T. & Fujita, M., 12 1 2019, : : Scientific reports. 9, 1, 16825.

研究成果: ジャーナルへの寄稿記事

公開

Identification of drug transporters contributing to oxaliplatin-induced peripheral neuropathy

Fujita, S., Hirota, T., Sakiyama, R., Baba, M. & Ieiri, I., 2 2019, : : Journal of Neurochemistry. 148, 3, p. 373-385 13 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Identification of lipophilic ligands of Siglec5 and -14 that modulate innate immune responses

Suematsu, R., Miyamoto, T., Saijo, S., Yamasaki, S., Tada, Y., Yoshida, H. & Miyake, Y., 11 8 2019, : : Journal of Biological Chemistry. 294, 45, p. 16776-16788 13 p.

研究成果: ジャーナルへの寄稿記事

公開

Improvement of stilbenoid production by 2-hydroxypropyl-β-cyclodextrin in white mulberry (Morus alba L.) callus cultures

Komaikul, J., Kitisripanya, T., Likhitwitayawuid, K., Sritularak, B., Tanaka, H. & Putalun, W., 10 2 2019, : : Natural Product Research. 33, 19, p. 2762-2769 8 p.

研究成果: ジャーナルへの寄稿記事

Induction of cell fusion/apoptosis in anaplastic thyroid carcinoma in orthotopic mouse model by urokinase-specific oncolytic Sendai virus

Miyagawa, Y., Araki, K., Yamashita, T., Tanaka, S., Tanaka, Y., Tomifuji, M., Ueda, Y., Yonemitsu, Y., Shimada, H. & Shiotani, A., 1 1 2019, : : Head and Neck. 41, 9, p. 2873-2882 10 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib

Morii, I., Iwabuchi, Y., Mori, S., Suekuni, M., Natsume, T., Yoshida, K., Sugimoto, N., Kanemaki, M. T. & Fujita, M., 3 2019, : : Cancer Science. 110, 3, p. 1044-1053 10 p.

研究成果: ジャーナルへの寄稿記事

公開
2 引用 (Scopus)
1 引用 (Scopus)

Investigation of the endoplasmic reticulum localization of UDP-glucuronosyltransferase 2B7 with systematic deletion mutants

Miyauchi, Y., Kimura, S., Kimura, A., Kurohara, K., Hirota, Y., Fujimoto, K., Mackenzie, P. I., Tanaka, Y. & Ishii, Y., 5 2019, : : Molecular Pharmacology. 95, 5, p. 551-562 12 p.

研究成果: ジャーナルへの寄稿記事

In Vivo Imaging of the Intra-and Extracellular Redox Status in Rat Stomach with Indomethacin-Induced Gastric Ulcers Using Overhauser-Enhanced Magnetic Resonance Imaging

Yasukawa, K., Shigemi, R., Kanbe, T., Mutsumoto, Y., Oda, F., Ichikawa, K., Yamada, K. I., Tun, X. & Utsumi, H., 1 1 2019, : : Antioxidants and Redox Signaling. 30, 9, p. 1147-1161 15 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Isolation and identification of new anthraquinones from Rhamnus alaternus L and evaluation of their free radical scavenging activity

Ben Ammar, R., Miyamoto, T., Chekir-Ghedira, L., Ghedira, K. & Lacaille-Dubois, M. A., 1 17 2019, : : Natural Product Research. 33, 2, p. 280-286 7 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)