薬学研究院

研究成果

フィルター
記事
2014

Suppression of wear-particle-induced pro-inflammatory cytokine and chemokine production in macrophages via NF-κB decoy oligodeoxynucleotide: A preliminary report

Lin, T. H., Yao, Z., Sato, T., Keeney, M., Li, C., Pajarinen, J., Yang, F., Egashira, K. & Goodman, S. B., 1 1 2014, : : Acta Biomaterialia. 10, 8, p. 3747-3755 9 p.

研究成果: ジャーナルへの寄稿記事

30 引用 (Scopus)

The apelin-APJ system induces tumor arteriogenesis in hepatocellular carcinoma

Muto, J., Shirabe, K., Yoshizumi, T., Ikegami, T., Aishima, S., Ishigami, K., Yonemitsu, Y., Ikeda, T., Soejima, Y. & Maehara, Y., 10 1 2014, : : Anticancer research. 34, 10, p. 5313-5320 8 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

The feasibility and clinical effects of dendritic cell-based immunotherapy targeting synthesized peptides for recurrent ovarian cancer

Kobayashi, M., Chiba, A., Izawa, H., Yanagida, E., Okamoto, M., Shimodaira, S., Yonemitsu, Y., Shibamoto, Y., Suzuki, N. & Nagaya, M., 5 7 2014, : : Journal of Ovarian Research. 7, 1, 48.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Therapeutic angiogenesis: Recent and future prospects of gene therapy in peripheral artery disease

Tanaka, M., Taketomi, K. & Yonemitsu, Y., 9 1 2014, : : Current Gene Therapy. 14, 4, p. 300-308 9 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Therapeutic effect of intratumoral injections of dendritic cells for locally recurrent gastric cancer: A case report

The DC-vaccine study group at the Japan Society of Innovative Cell Therapy (J-SICT), 12 19 2014, : : World Journal of Surgical Oncology. 12, 1, 390.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Tumor-derived interleukin-1 promotes lymphangiogenesis and lymph node metastasis through M2-type macrophages

Watari, K., Shibata, T., Kawahara, A., Sata, K. I., Nabeshima, H., Shinoda, A., Abe, H., Azuma, K., Murakami, Y., Izumi, H., Takahashi, T., Kage, M., Kuwano, M. & Ono, M., 6 12 2014, : : PloS one. 9, 6, e99568.

研究成果: ジャーナルへの寄稿記事

31 引用 (Scopus)
2013

Dendritic Cell-Based Immunotherapy Targeting Synthesized Peptides for Advanced Biliary Tract Cancer

Kobayashi, M., Sakabe, T., Abe, H., Tanii, M., Takahashi, H., Chiba, A., Yanagida, E., Shibamoto, Y., Ogasawara, M., Tsujitani, S. I., Koido, S., Nagai, K., Shimodaira, S., Okamoto, M., Yonemitsu, Y., Suzuki, N. & Nagaya, M., 9 1 2013, : : Journal of Gastrointestinal Surgery. 17, 9, p. 1609-1617 9 p.

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

DVC1-0101 to treat peripheral arterial disease: A phase I/IIa open-label dose-escalation clinical trial

Yonemitsu, Y., Matsumoto, T., Itoh, H., Okazaki, J., Uchiyama, M., Yoshida, K., Onimaru, M., Onohara, T., Inoguchi, H., Kyuragi, R., Shimokawa, M., Ban, H., Tanaka, M., Inoue, M., Shu, T., Hasegawa, M., Nakanishi, Y. & Maehara, Y., 3 2013, : : Molecular Therapy. 21, 3, p. 707-714 8 p.

研究成果: ジャーナルへの寄稿記事

34 引用 (Scopus)

Erlotinib resistance in lung cancer cells mediated by integrin β1/Src/Akt-driven bypass signaling

Kanda, R., Kawahara, A., Watari, K., Murakami, Y., Sonoda, K., Maeda, M., Fujita, H., Kage, M., Uramoto, H., Costa, C., Kuwano, M. & Ono, M., 10 15 2013, : : Cancer Research. 73, 20, p. 6243-6253 11 p.

研究成果: ジャーナルへの寄稿記事

75 引用 (Scopus)

Ex vivo generation of highly purified and activated natural killer cells from human peripheral blood

Saito, S., Harada, Y., Morodomi, Y., Onimaru, M., Yoshida, K., Kyuragi, R., Matsubara, H. & Yonemitsu, Y., 8 1 2013, : : Human Gene Therapy Methods. 24, 4, p. 241-252 12 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Impact of dendritic cell vaccines pulsed with Wilms' tumour-1 peptide antigen on the survival of patients with advanced non-small cell lung cancers

Takahashi, H., Okamoto, M., Shimodaira, S., Tsujitani, S. I., Nagaya, M., Ishidao, T., Kishimoto, J. & Yonemitsu, Y., 3 1 2013, : : European Journal of Cancer. 49, 4, p. 852-859 8 p.

研究成果: ジャーナルへの寄稿記事

37 引用 (Scopus)

Mutant MCP-1 protein delivery from layer-by-layer coatings onorthopedic implants to modulate inflammatory response

Keeney, M., Waters, H., Barcay, K., Jiang, X., Yao, Z., Pajarinen, J., Egashira, K., Goodman, S. B. & Yang, F., 12 1 2013, : : Biomaterials. 34, 38, p. 10287-10295 9 p.

研究成果: ジャーナルへの寄稿記事

32 引用 (Scopus)

N-myc downstream-regulated gene 1 promotes tumor inflammatory angiogenesis through JNK activation and autocrine loop of interleukin-1α by human gastric cancer cells

Murakami, Y., Watari, K., Shibata, T., Uba, M., Ureshino, H., Kawahara, A., Abe, H., Izumi, H., Mukaida, N., Kuwano, M. & Ono, M., 8 30 2013, : : Journal of Biological Chemistry. 288, 35, p. 25025-25037 13 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Pitavastatin-incorporated nanoparticle-eluting stents attenuate in-stent stenosis without delayed endothelial healing effects in a porcine coronary artery model

Tsukie, N., Nakano, K., Matoba, T., Masuda, S., Iwata, E., Miyagawa, M., Zhao, G., Meng, W., Kishimoto, J., Sunagawa, K. & Egashira, K., 2 4 2013, : : Journal of atherosclerosis and thrombosis. 20, 1, p. 32-45 14 p.

研究成果: ジャーナルへの寄稿記事

35 引用 (Scopus)

Structure, synthesis, and biological activity of a C-20 bisacetylenic alcohol from a marine sponge Callyspongia sp.

Shirouzu, T., Watari, K., Ono, M., Koizumi, K., Saiki, I., Tanaka, C., Van Soest, R. W. M. & Miyamoto, T., 7 26 2013, : : Journal of Natural Products. 76, 7, p. 1337-1342 6 p.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

Studies on lymphangiogenesis inhibitors from Korean and Japanese crude drugs

Jeong, D., Watari, K., Shirouzu, T., Ono, M., Koizumi, K., Saiki, I., Kim, Y. C., Tanaka, C., Higuchi, R. & Miyamoto, T., 1 1 2013, : : Biological and Pharmaceutical Bulletin. 36, 1, p. 152-157 6 p.

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)
2012

A somatostatin analogue, octreotide, ameliorates intestinal ischemia-reperfusion injury through the early induction of heme oxygenase-1

Takano, T., Yonemitsu, Y., Saito, S., Itoh, H., Onohara, T., Fukuda, A., Takai, M. & Maehara, Y., 6 15 2012, : : Journal of Surgical Research. 175, 2, p. 350-358 9 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

ATR-Chk1 signaling pathway and homologous recombinational repair protect cells from 5-fluorouracil cytotoxicity

Fujinaka, Y., Matsuoka, K., Iimori, M., Tuul, M., Sakasai, R., Yoshinaga, K., Saeki, H., Morita, M., Kakeji, Y., Gillespie, D. A., Yamamoto, K. I., Takata, M., Kitao, H. & Maehara, Y., 3 1 2012, : : DNA Repair. 11, 3, p. 247-258 12 p.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

BioKnife, a uPA activity-dependent oncolytic sendai virus, eliminates pleural spread of malignant mesothelioma via simultaneous stimulation of uPA expression

Morodomi, Y., Yano, T., Kinoh, H., Harada, Y., Saito, S., Kyuragi, R., Yoshida, K., Onimaru, M., Shoji, F., Yoshida, T., Ito, K., Shikada, Y., Maruyama, R., Hasegawa, M., Maehara, Y. & Yonemitsu, Y., 4 2012, : : Molecular Therapy. 20, 4, p. 769-777 9 p.

研究成果: ジャーナルへの寄稿記事

16 引用 (Scopus)

Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration

Suzuki, M., Tsujikawa, M., Itabe, H., Du, Z. J., Xie, P., Matsumura, N., Fu, X., Zhang, R., Sonoda, K. H., Egashira, K., Hazen, S. L. & Kamei, M., 8 14 2012, : : Journal of cell science. 125, 10, p. 2407-2415 9 p.

研究成果: ジャーナルへの寄稿記事

72 引用 (Scopus)

Clinical and immunologic evaluation of dendritic cell-based immunotherapy in combination with gemcitabine and/or S-1 in patients with advanced pancreatic carcinoma

Kimura, Y., Tsukada, J., Tomoda, T., Takahashi, H., Imai, K., Shimamura, K., Sunamura, M., Yonemitsu, Y., Shimodaira, S., Koido, S., Homma, S. & Okamoto, M., 3 1 2012, : : Pancreas. 41, 2, p. 195-205 11 p.

研究成果: ジャーナルへの寄稿記事

99 引用 (Scopus)

Clinical application for intra-coronary nanodds devices

Nakano, K., Egashira, K. & Yufu, T., 1 1 2012, : : Drug Delivery System. 27, 4, p. 275-282 8 p.

研究成果: ジャーナルへの寄稿記事

31 引用 (Scopus)

Endogenous cardiac troponin T modulates Ca2+-mediated smooth muscle contraction

Kajioka, S., Takahashi-Yanaga, F., Shahab, N., Onimaru, M., Matsuda, M., Takahashi, R., Asano, H., Morita, H., Morimoto, S., Yonemitsu, Y., Hayashi, M., Seki, N., Sasaguri, T., Hirata, M., Nakayama, S. & Naito, S., 12 1 2012, : : Scientific reports. 2, 979.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

MutT Homolog-1 Attenuates Oxidative DNA Damage and Delays Photoreceptor Cell Death in Inherited Retinal Degeneration

Murakami, Y., Ikeda, Y., Yoshida, N., Notomi, S., Hisatomi, T., Oka, S., De Luca, G., Yonemitsu, Y., Bignami, M., Nakabeppu, Y. & Ishibashi, T., 10 1 2012, : : American Journal of Pathology. 181, 4, p. 1378-1386 9 p.

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

Nanoparticle-mediated delivery of pioglitazone enhances therapeutic neovascularization in a murine model of hindlimb ischemia

Nagahama, R., Matoba, T., Nakano, K., Kim-Mitsuyama, S., Sunagawa, K. & Egashira, K., 11 1 2012, : : Arteriosclerosis, thrombosis, and vascular biology. 32, 10, p. 2427-2434 8 p.

研究成果: ジャーナルへの寄稿記事

32 引用 (Scopus)

NDRG1/Cap43/Drg-1 may predict tumor angiogenesis and poor outcome in patients with lung cancer

Azuma, K., Kawahara, A., Hattori, S., Taira, T., Tsurutani, J., Watari, K., Shibata, T., Murakami, Y., Takamori, S., Ono, M., Izumi, H., Kage, M., Yanagawa, T., Nakagawa, K., Hoshino, T. & Kuwano, M., 1 1 2012, : : Journal of Thoracic Oncology. 7, 5, p. 779-789 11 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

N-myc downstream regulated gene 1 (NDRG1) promotes metastasis of human scirrhous gastric cancer cells through epithelial mesenchymal transition

Ureshino, H., Murakami, Y., Watari, K., Izumi, H., Kawahara, A., Kage, M., Arao, T., Nishio, K., Yanagihara, K., Kinoshita, H., Kuwano, M. & Ono, M., 7 23 2012, : : PloS one. 7, 7, e41312.

研究成果: ジャーナルへの寄稿記事

29 引用 (Scopus)

Stress augments insulin resistance and prothrombotic state: Role of visceral adipose-derived monocyte chemoattractant protein-1

Uchida, Y., Takeshita, K., Yamamoto, K., Kikuchi, R., Nakayama, T., Nomura, M., Cheng, X. W., Egashira, K., Matsushita, T., Nakamura, H. & Murohara, T., 6 1 2012, : : Diabetes. 61, 6, p. 1552-1561 10 p.

研究成果: ジャーナルへの寄稿記事

53 引用 (Scopus)

The antitumor effect of a novel angiogenesis inhibitor (an octahydronaphthalene derivative) targeting both VEGF receptor and NF-κB pathway

Watari, K., Nakamura, M., Fukunaga, Y., Furuno, A., Shibata, T., Kawahara, A., Hosoi, F., Kuwano, T., Kuwano, M. & Ono, M., 7 15 2012, : : International Journal of Cancer. 131, 2, p. 310-321 12 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)
2011

A natural anti-inflammatory enone fatty acid inhibits angiogenesis by attenuating nuclear factor-κB signaling in vascular endothelial cells

Furuno, A., Watari, K., Mamiyo, N., Yuichi, F., Jung, J. H. & Ono, M., 2 1 2011, : : International journal of oncology. 38, 2, p. 493-501 9 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Angiogenic and lymphangiogenic cascades in the tumor microenvironment

Onimaru, M. & Yonemitsu, Y., 1 1 2011, : : Frontiers in Bioscience - Scholar. 3 S, 1, p. 216-225 10 p.

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

Antagonism of VEGF by genetically engineered dendritic cells is essential to induce antitumor immunity against malignant ascites

Sugiyama, M., Kakeji, Y., Tsujitani, S., Harada, Y., Onimaru, M., Yoshida, K., Tanaka, S., Emi, Y., Morita, M., Morodomi, Y., Hasegawa, M., Maehara, Y. & Yonemitsu, Y., 3 1 2011, : : Molecular Cancer Therapeutics. 10, 3, p. 540-549 10 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

Cytokine-based high log-scale expansion of functional human dendritic cells from cord-blood CD34-positive cells

Harada, Y., Okada-Nakanishi, Y., Ueda, Y., Tsujitani, S., Saito, S., Fuji-Ogawa, T., Iida, A., Hasegawa, M., Ichikawa, T. & Yonemitsu, Y., 12 1 2011, : : Scientific reports. 1, 174.

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

Dramatic improvement of DC-based immunotherapy against various malignancies

Harada, Y. & Yonemitsu, Y., 6 1 2011, : : Frontiers in Bioscience. 16, 6, p. 2233-2242 10 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Imatinib mesylate-incorporated nanoparticle-eluting stent attenuates in-stent neointimal formation in porcine coronary arteries

Masuda, S., Nakano, K., Funakoshi, K., Zhao, G., Meng, W., Kimura, S., Matoba, T., Miyagawa, M., Iwata, E., Sunagawa, K. & Egashira, K., 12 22 2011, : : Journal of atherosclerosis and thrombosis. 18, 12, p. 1043-1053 11 p.

研究成果: ジャーナルへの寄稿記事

35 引用 (Scopus)

Macrophage infiltration predicts a poor prognosis for human ewing sarcoma

Fujiwara, T., Fukushi, J. I., Yamamoto, S., Matsumoto, Y., Setsu, N., Oda, Y., Yamada, H., Okada, S., Watari, K., Ono, M., Kuwano, M., Kamura, S., Iida, K., Okada, Y., Koga, M. & Iwamoto, Y., 9 1 2011, : : American Journal of Pathology. 179, 3, p. 1157-1170 14 p.

研究成果: ジャーナルへの寄稿記事

76 引用 (Scopus)

Mesenchymal stem cells stably transduced with a dominant-negative inhibitor of CCL2 greatly attenuate bleomycin-induced lung damage

Saito, S., Nakayama, T., Hashimoto, N., Miyata, Y., Egashira, K., Nakao, N., Nishiwaki, S., Hasegawa, M., Hasegawa, Y. & Naoe, T., 9 1 2011, : : American Journal of Pathology. 179, 3, p. 1088-1094 7 p.

研究成果: ジャーナルへの寄稿記事

31 引用 (Scopus)

Nanoparticle-mediated delivery of pitavastatin into lungs ameliorates the development and induces regression of monocrotaline-induced pulmonary artery hypertension

Chen, L., Nakano, K., Kimura, S., Matoba, T., Iwata, E., Miyagawa, M., Tsujimoto, H., Nagaoka, K., Kishimoto, J., Sunagawa, K. & Egashira, K., 2 1 2011, : : Hypertension. 57, 2, p. 343-350 8 p.

研究成果: ジャーナルへの寄稿記事

60 引用 (Scopus)

Neutrophil-dominant experimental autoimmune uveitis in CC-chemokine receptor 2 knockout mice

Sonoda, K. H., Yoshimura, T., Egashira, K., Charo, I. F. & Ishibashi, T., 3 1 2011, : : Acta Ophthalmologica. 89, 2, p. e180-e188

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

N-myc downstream regulated gene1/Cap43 overexpression suppresses tumor growth by hepatic cancer cells through cell cycle arrest at the G0/G1 phase

Akiba, J., Murakami, Y., Noda, M., Watari, K., Ogasawara, S., Yoshida, T., Kawahara, A., Sanada, S., Yasumoto, M., Yamaguchi, R., Kage, M., Kuwano, M., Ono, M. & Yano, H., 11 1 2011, : : Cancer Letters. 310, 1, p. 25-34 10 p.

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)

Pigment epithelium-derived factor gene therapy targeting retinal ganglion cell injuries: Neuroprotection against loss of function in two animal models

Miyazaki, M., Ikeda, Y., Yonemitsu, Y., Goto, Y., Murakami, Y., Yoshida, N., Tabata, T., Hasegawa, M., Tobimatsu, S., Sueishi, K. & Ishibashi, T., 5 1 2011, : : Human Gene Therapy. 22, 5, p. 559-565 7 p.

研究成果: ジャーナルへの寄稿記事

24 引用 (Scopus)

Provision of continuous maturation signaling to dendritic cells by RIG-I-stimulating cytosolic RNA synthesis of Sendai virus

Okano, S., Yonemitsu, Y., Shirabe, K., Kakeji, Y., Maehara, Y., Harada, M., Yoshikai, Y., Inoue, M., Hasegawa, M. & Sueishi, K., 2 1 2011, : : Journal of Immunology. 186, 3, p. 1828-1839 12 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)
3 引用 (Scopus)

Repeated and targeted transfer of angiogenic plasmids into the infarcted rat heart via ultrasound targeted microbubble destruction enhances cardiac repair

Fujii, H., Li, S. H., Wu, J., Miyagi, Y., Yau, T. M., Rakowski, H., Egashira, K., Guo, J., Weisel, R. D. & Li, R. K., 8 1 2011, : : European heart journal. 32, 16, p. 2075-2084 10 p.

研究成果: ジャーナルへの寄稿記事

86 引用 (Scopus)
2010
14 引用 (Scopus)

Carbon-ion beam treatment induces systemic antitumor immunity against murine squamous cell carcinoma

Matsunaga, A., Ueda, Y., Yamada, S., Harada, Y., Shimada, H., Hasegawa, M., Tsujii, H., Ochiai, T. & Yonemitsu, Y., 8 1 2010, : : Cancer. 116, 15, p. 3740-3748 9 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes

Wu, Y., Sommers, J. A., Suhasini, A. N., Leonard, T., Deakyne, J. S., Mazin, A. V., Shin-ya, K., Kitao, H. & Brosh, R. M., 11 11 2010, : : Blood. 116, 19, p. 3780-3791 12 p.

研究成果: ジャーナルへの寄稿記事

54 引用 (Scopus)

Four new cembrane diterpenes isolated from an Okinawan soft coral Lobophytum crassum with inhibitory effects on nitric oxide production

Wanzola, M., Furuta, T., Kohno, Y., Fukumitsu, S., Yasukochi, S., Watari, K., Tanaka, C., Higuchi, R. & Miyamoto, T., 9 1 2010, : : Chemical and Pharmaceutical Bulletin. 58, 9, p. 1203-1209 7 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

High expression of BUBR1 is one of the factors for inducing DNA aneuploidy and progression in gastric cancer

Ando, K., Kakeji, Y., Kitao, H., Iimori, M., Zhao, Y., Yoshida, R., Oki, E., Yoshinaga, K., Matumoto, T., Morita, M., Sakaguchi, Y. & Maehara, Y., 3 1 2010, : : Cancer Science. 101, 3, p. 639-645 7 p.

研究成果: ジャーナルへの寄稿記事

40 引用 (Scopus)