研究成果

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記事
1993

Inducing ability of co-planar PCBs toward bilirubin UDP-glucuronyltransferase of liver microsomes: the remarkable difference between guinea pigs and rats

Oguri, K., Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H. & Yoshimura, H., 1 1 1993, : : Fukuoka igaku zasshi = Hukuoka acta medica. 84, 5, p. 175-180 6 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Induction of bilirubin UDP-glucuronyltransferase and P-450 4A subfamily in guinea pigs by treatment with coplanar PCB

Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H., Oguri, K., Yoshimura, H. & Funae, Y., 1993, : : Japanese Journal of Toxicology and Environmental Health. 39, 1

研究成果: ジャーナルへの寄稿記事

Modification of the gluconeogenesis is not involved in the co-planar PCB toxicity in highly sensitive guinea pigs

Oguri, K., Hatsumura, M., Ishii, Y., Koga, Y., Ariyoshi, N. & Yoshimura, H., 12 1993, : : Chemosphere. 27, 11, p. 2295-2303 9 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

New Fluorinated Dopamine D2 Ligands with Benzofuran Skeleton. The Synthesis and in Vitro Evaluation

Sasaki, S., Fukumura, T., Takehara, S., Takao, F., Watanabe, K., Obana, N. & Maeda, M., 1 1 1993, : : Chemical and Pharmaceutical Bulletin. 41, 2, p. 296-300 5 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Picrotoxin as a potent inducer of rat hepatic cytochrome P450, CYP2b1 and CYP2b2

Yamada, H., Fujisaki, H., Kaneko, H., Ishii, Y., Hamaguchi, T. & Oguri, K., 5 5 1993, : : Biochemical Pharmacology. 45, 9, p. 1783-1789 7 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

Purification and Characterization of a Morphine UDP-Glucuronyltransferase Isoform from Untreated Rat Liver

Ishii, Y., Oguri, K. & Yoshimura, H., 1 1 1993, : : Biological and Pharmaceutical Bulletin. 16, 8, p. 754-758 5 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

Purification and processing of rat liver procathepsin B

Kawabata, T., Nishimura, Y., Higaki, M. & Kato, K., 1 1 1993, : : Journal of Biochemistry. 113, 3, p. 389-394 6 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

Regioselective synthesis of maturone via Lewis acid catalyzed Diels-Alder reaction

Aso, M., Ojida, A., Yang, G. & Kanematsu, K., 1 1 1993, : : Heterocycles. 35, 1, p. 33-36 4 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Serotonin-induced coronary spasm in a swine model: A minor role of defective endothelium-derived relaxing factor

Fukai, T., Egashira, K., Hata, H., Numaguchi, K., Ohara, Y., Takahashi, T., Tomoike, H. & Takeshita, A., 1 1 1993, : : Circulation. 88, 4 I, p. 1922-1930 9 p.

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

Stabilization of lysozyme by the introduction of gly-pro sequence

Ueda, T., Tamura, T., Maeda, Y., Hashimoto, Y., Miki, T., Yamada, H. & Imoto, T., 2 1 1993, : : Protein Engineering, Design and Selection. 6, 2, p. 183-187 5 p.

研究成果: ジャーナルへの寄稿記事

35 引用 (Scopus)
4 引用 (Scopus)

Synthesis and evaluation of 1-{1-[5-(2′-[18F]Fluoroethyl)-2-thienyl]-cyclohexyl}piperidine as a potential in vivo radioligand for the NMDA receptor-Channel complex

Orita, K., Sasaki, S., Maeda, M., Hashimoto, A., Nishikawa, T., Yugami, T. & Umezu, K., 10 1993, : : Nuclear Medicine and Biology. 20, 7, p. 865-873 9 p.

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

Synthesis and in vivo evaluation of a new fluorine‐18 labeled dopamine D2 radioligand synthesis with benzofuran benzamide skeleton

Takao, F., Sasaki, S., Maeda, M., Fukumura, T., Tahara, T., Masuda, K. & Ichiya, Y., 12 1993, : : Journal of Labelled Compounds and Radiopharmaceuticals. 33, 12, p. 1107-1112 6 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

The primary structures and properties of non‐stomach lysozymes of sheep and cow, and implication for functional divergence of lysozyme

ITO, Y., YAMADA, H., NAKAMURA, M., YOSHIKAWA, A., Ueda, T. & IMOTO, T., 1 1 1993, : : European Journal of Biochemistry. 213, 2, p. 649-658 10 p.

研究成果: ジャーナルへの寄稿記事

36 引用 (Scopus)
14 引用 (Scopus)

The role of endothelial function in the pathogenesis of coronary spasm in humans

Kensuke, E., Tetsuzi, I., Akira, Y., Yoshitaka, H. & Akira, T., 1 1 1993, : : JAPANESE CIRCULATION JOURNAL. 56, p. 1319-1323 5 p.

研究成果: ジャーナルへの寄稿記事

1994

18F-labeled analogs of arachidonic acid: Synthesis and preliminary in vivo distribution in rats of methyl ω-[18F] fluoroarachidonate

Nagatsugi, F., Hokazono, J., Sasaki, S. & Maeda, M., 1 1 1994, : : Journal of Labelled Compounds and Radiopharmaceuticals. 35, p. 337-338 2 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

3-Acetoxy-2,2′-bi-1H-indol as a novel inhibitor of ATP binding to DnaA, the protein initiating chromosomal replication in escherichia coli

Sasaki, S., Mizushima, T., Hashimoto, T., Maeda, M. & Kazuhisa, S., 7 21 1994, : : Bioorganic and Medicinal Chemistry Letters. 4, 14, p. 1771-1774 4 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

8-[18F]fluorooctanoic acid and its β-substituted derivatives as potential agents for cerebral fatty acid studies: Synthesis and biodistribution

Nagatsugi, F., Sasaki, S. & Maeda, M., 1 1 1994, : : Nuclear Medicine and Biology. 21, 6, p. 809-817 9 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

Antitumor effect of camptothecin analog on liver metastatic model of human colon cancer in nude mice

Takiguchi, S., Shimazoe, T. & Kono, A., 4 1994, : : Gan to kagaku ryoho. Cancer & chemotherapy. 21, 5, p. 705-708 4 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

ATP sensitive potassium channels are involved in adenosine A2 receptor mediated coronary vasodilatation in the dog

Akatsuka, Y., Egashira, K., Katsuda, Y., Narishige, T., Ueno, H., Shimokawa, H. & Takeshita, A., 6 1994, : : Cardiovascular research. 28, 6, p. 906-911 6 p.

研究成果: ジャーナルへの寄稿記事

59 引用 (Scopus)

Beneficial effect of cholesterol-lowering therapy on endothelium-dependent coronary vasodilation in patients with hypercholesterolemia

Egashira, K. & Takeshita, A., 1 1 1994, : : Annals of the New York Academy of Sciences. 748, p. 622-625 4 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Bioactive terpenoids from Octocorallia, I. Bioactive diterpenoids: Litophynols A and B from the mucus of the soft coral Litophyton sp.

Miyamoto, T., Yamada, K., Ikeda, N., Komori, T. & Higuchi, R., 9 1 1994, : : Journal of Natural Products. 57, 9, p. 1212-1219 8 p.

研究成果: ジャーナルへの寄稿記事

48 引用 (Scopus)

Constituents of holothuroideae, IV. Isolation and structure of three new cerebrosides, CE‐2b, CE‐2c and CE‐2d, from the sea cucumber Cucumaria echinata

Higuchi, R., Inagaki, M., Togawa, K., Miyamoto, T. & Komori, T., 1 1 1994, : : Liebigs Annalen der Chemie. 1994, 1, p. 79-81 3 p.

研究成果: ジャーナルへの寄稿記事

32 引用 (Scopus)

Constituents of Holothuroideae, V. Isolation and Structure of Cerebrosides from the Sea Cucumber Pentacta australis

Higuchi, R., Inagaki, M., Togawa, K., Miyamoto, T. & Komori, T., 1 1 1994, : : Liebigs Annalen der Chemie. 1994, 7, p. 653-658 6 p.

研究成果: ジャーナルへの寄稿記事

60 引用 (Scopus)

Determination of tetrahydrocannabinolic acid—carrier protein conjugate by matrix‐assisted laser desorption/ionization mass spectrometry and antibody formation

Goto, Y., Shima, Y., Morimoto, S., Shoyama, Y., Murakami, H., Kusai, A. & Nojima, K., 1 1 1994, : : Organic Mass Spectrometry. 29, 11, p. 668-671 4 p.

研究成果: ジャーナルへの寄稿記事

41 引用 (Scopus)

Effect of coplanar PCB on gluconeogenesis and lipid metabolism: Comparison between rats and guinea pigs

Hatsumura, M., Ishida, T., Ishii, Y., Ariyoshi, N., Koga, Y., Oguri, K. & Yoshimura, H., 1 1 1994, : : Japanese Journal of Toxicology and Environmental Health. 40, 1, p. P27

研究成果: ジャーナルへの寄稿記事

Effects of intracoronary infusion of atrial natriuretic peptide on pacing- induced myocardial ischemia in patients with effort angina pectoris

Kai, H., Egashira, K., Hirooka, Y., Sugimachi, M., Suzuki, S., Kuga, T., Mohri, K., Urabe, Y., Inou, T. & Takeshita, A., 12 1 1994, : : Coronary Artery Disease. 5, 12, p. 987-994 8 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Effects of N-nitro-L-arginine on coronary artery tone and reactive hyperemia after brief coronary occlusion in conscious dogs

Muramatsu, K. H., Numaguchi, K. T., Egashira, K., Takahashi, T., Kasuya, H. & Takeshita, A., 1 1 1994, : : Coronary Artery Disease. 5, 10, p. 815-820 6 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Establishment and characterization of PTHrP-producing human pancreatic cancer cell line

Nishi, Y., Haji, M., Takayanagi, R., Iguchi, H., Shimazoe, T., Hirata, J. & Nawata, H., 1 1 1994, : : International journal of oncology. 5, 1, p. 33-39 7 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Formation of α-helix 88-98 is essential in the establishment of higher-order structure from reduced lysozyme

Ueda, T., Nakashima, A., Hashimoto, Y., Miki, T., Yamada, H. & Imoto, T., 1 27 1994, : : Journal of Molecular Biology. 235, 4, p. 1312-1317 6 p.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)
56 引用 (Scopus)

Immunocytochemical localization of cathepsin L in the synovial lining cells of the rat temporomandibular joint

Kiyoshima, T., Kido, M. A., Nishimura, Y., Himeno, M., Tsukuba, T., Tashiro, H., Yamamoto, K. & Tanaka, T., 1 1 1994, : : Archives of Oral Biology. 39, 12, p. 1049-1056 8 p.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

Induction of bilirubin UDP-glucuronyltransferase and CYP4A1 P450 by co-planar PCBs: Different responsiveness of guinea pigs and rats

Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H., Oguri, K., Funae, Y. & Yoshimura, H., 2 1994, : : Chemosphere. 28, 3, p. 639-645 7 p.

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

Influence of Additional Therapy with Zonisamide (Excegran) on Protein Binding and Metabolism of Carbamazepine

Minami, T., Ieiri, I., Ohtsubo, K., Hirakawa, Y., Ueda, K., Higuchi, S. & Aoyama, T., 9 1994, : : Epilepsia. 35, 5, p. 1023-1025 3 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Isolation and Characterization of 101-Succinimide Lysozyme That Possesses the Cyclic Imide at Asp101-Gly102

Tomizawa, H., Ueda, T., Imoto, T. & Yamada, H., 7 1 1994, : : Biochemistry. 33, 29, p. 8770-8774 5 p.

研究成果: ジャーナルへの寄稿記事

41 引用 (Scopus)

Localization of cathepsins B, D, and L in the rat osteoclast by immuno-light and -electron microscopy

Goto, T., Tanaka, T., Kiyoshima, T., Moroi, R., Tsukuba, T., Yamamoto, K., Nishimura, Y. & Himeno, M., 1 1 1994, : : Histochemistry. 101, 1, p. 33-40 8 p.

研究成果: ジャーナルへの寄稿記事

77 引用 (Scopus)

Novel calcium ionophores: Supramolecular complexation by the hydroxylated-bistetrahydrofuran skeleton of potent antitumor Annonaceous acetogenins

Sasaki, S., Naito, H., Maruta, K., Kawahara, E. & Maeda, M., 5 16 1994, : : Tetrahedron Letters. 35, 20, p. 3337-3340 4 p.

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

Post-harvest degradation of carotenoid glucose esters in saffron

Morimoto, S., Umezaki, Y., Shoyama, Y., Saito, H., Nishi, K. & Irino, N., 10 31 1994, : : Planta medica. 60, 5, p. 438-440 3 p.

研究成果: ジャーナルへの寄稿記事

50 引用 (Scopus)

Production of lithospermic acid B and rosmarinic acid in callus tissue and regenerated plantlets of salvia miltiorrhiza

Morimoto, S., Goto, Y. & Shoyama, Y., 6 1 1994, : : Journal of Natural Products. 57, 6, p. 817-823 7 p.

研究成果: ジャーナルへの寄稿記事

49 引用 (Scopus)

Purification and characterization of dog liver microsomal epoxide hydrolase

Ariyoshi, N., Tanaka, M., Ishii, Y. & Oguri, K., 1 1 1994, : : Journal of biochemistry. 115, 5, p. 985-990 6 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

Purification of a Phenobarbital-Inducible Morphine UDP-Glucuronosyltransferase Isoform, Absent from Gunn Rat Liver

Ishii, Y., Tsuruda, K., Tanaka, M. & Oguri, K., 12 1 1994, : : Archives of Biochemistry and Biophysics. 315, 2, p. 345-351 7 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

Reduction in serum cholesterol with pravastatin improves endothelium- dependent coronary vasomotion in patients with hypercholesterolemia

Egashira, K., Hirooka, Y., Kai, H., Sugimachi, M., Suzuki, S., Inou, T. & Takeshita, A., 1 1 1994, : : Circulation. 89, 6, p. 2519-2524 6 p.

研究成果: ジャーナルへの寄稿記事

610 引用 (Scopus)

Reduction of disulfide bonds in proteins by 2-aminothiophenol under weakly acidic conditions

Abe, Y., Ueda, T. & Imoto, T., 1994, : : Journal of Biochemistry. 115, 1, p. 52-67 16 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Role of protein kinase C-mediated pathway in the pathogenesis of coronary artery spasm in a swine model

Ito, A., Shimokawa, H., Nakaike, R., Fukai, T., Sakata, M., Takayanagi, T., Egashira, K. & Takeshita, A., 11 1994, : : Circulation. 90, 5, p. 2425-2431 7 p.

研究成果: ジャーナルへの寄稿記事

45 引用 (Scopus)
8 引用 (Scopus)

Synthesis of 20‐[18F]fluoroarachidonic acid: A potential phospholipid metabolic agent

Nagatsugi, F., Hokazono, J., Sasaki, S. & Maeda, M., 1 1 1994, : : Journal of Labelled Compounds and Radiopharmaceuticals. 34, 12, p. 1121-1127 7 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Synthesis of annulated furans with various 3-substituents via a sequential furannulation/ene route

Ojida, A., Abe, A. & Kanematsu, K., 12 1 1994, : : Heterocycles. 38, 12, p. 2585-2588 4 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Synthesis of new fluoride-18 labeled benzofuran benzamide and its in vivo evaluation as a dopamine D2 radioligand

Sasaki, S., Takao, F., Maeda, M., Fukumura, T., Masuda, K. & Ichiya, Y., 1994, : : Journal of Labelled Compounds and Radiopharmaceuticals. 35, p. 435-436 2 p.

研究成果: ジャーナルへの寄稿記事

The role of net charge on the renaturation of reduced lysozyme by the sulfhydryl-disulfide interchange reaction

Maeda, Y., Ueda, T., Yamada, H. & Imoto, T., 10 1 1994, : : Protein Engineering, Design and Selection. 7, 10, p. 1249-1254 6 p.

研究成果: ジャーナルへの寄稿記事

21 引用 (Scopus)