研究成果 1976 2020

2020

An estimated quantitative lateral flow immunoassay for determination of artesunate using monoclonal antibody

Kitisripanya, T., Sermpradit, W., Sakamoto, S., Tanaka, H. & Putalun, W., 2 1 2020, : : Biomedical Chromatography. 34, 2, e4718.

研究成果: ジャーナルへの寄稿記事

Immunoassay
Monoclonal Antibodies
artesunate
Immunosorbents
Drug Compounding
公開
gemcitabine
Coenzymes
Diphosphonates
Oxidoreductases
Cell Line
gemcitabine
Diphosphonates
Oxidoreductases
Cell Line
Pancreatic Neoplasms

Bidirectional regulation between NDRG1 and GSK3β controls tumor growth and is targeted by differentiation inducing factor-1 in glioblastoma

Ito, H., Watari, K., Shibata, T., Miyamoto, T., Murakami, Y., Nakahara, Y., Izumi, H., Wakimoto, H., Kuwano, M., Abe, T. & Ono, M., 1 15 2020, : : Cancer Research. 80, 2, p. 234-248 15 p.

研究成果: ジャーナルへの寄稿記事

Glioblastoma
Growth
Genes
Neoplasms
1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone

Crystal structure of the complex of the interaction domains of Escherichia coli DnaB helicase and DnaC helicase loader: structural basis implying a distortion-accumulation mechanism for the DnaB ring opening caused by DnaC binding

Nagata, K., Okada, A., Ohtsuka, J., Ohkuri, T., Akama, Y., Sakiyama, Y., Miyazaki, E., Horita, S., Katayama, T., Ueda, T. & Tanokura, M., 1 1 2020, : : Journal of biochemistry. 167, 1, p. 1-14 14 p.

研究成果: ジャーナルへの寄稿記事

公開
DnaB Helicases
Loaders
Molecular Models
Escherichia coli
Crystal structure

GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity

Fujiyama, H., Tsuji, T., Hironaka, K., Yoshida, K., Sugimoto, N. & Fujita, M., 1 1 2020, : : Journal of biochemistry. 167, 1, p. 15-24 10 p.

研究成果: ジャーナルへの寄稿記事

Glutamic Acid
Genes
p53 Genes
WD40 Repeats
Neoplasms

Mechanistic studies of nickel(II)-catalyzed direct alcoholysis of 8-aminoquinoline amides

Morimoto, H., Akkad, W., Deguchi, T. & Ohshima, T., 1 1 2020, : : Heterocycles. 101, 2, p. 471-485 15 p.

研究成果: ジャーナルへの寄稿記事

公開
Nickel
Amides
Deprotonation
Catalysts
Density functional theory

Rhodium(I)/Chiral Diene-Catalyzed Enantioselective Addition of Boronic Acids to N-Unsubstituted Isatin-Derived Ketimines

Yonesaki, R., Kusagawa, I., Morimoto, H., Hayashi, T. & Ohshima, T., 1 1 2020, (受理済み/印刷中) : : Chemistry - An Asian Journal.

研究成果: ジャーナルへの寄稿記事

Isatin
Boronic Acids
Rhodium
Enantioselectivity
Catalysts

Scandium(III) Triflate Catalyzed Direct Synthesis of N-Unprotected Ketimines

Kondo, Y., Kadota, T., Hirazawa, Y., Morisaki, K., Morimoto, H. & Ohshima, T., 1 3 2020, : : Organic Letters. 22, 1, p. 120-125 6 p.

研究成果: ジャーナルへの寄稿記事

Scandium
scandium
nitrogen compounds
synthesis
glycine

Sensitization of spinal itch transmission neurons in a mouse model of chronic itch requires an astrocytic factor

Koga, K., Yamagata, R., Kohno, K., Yamane, T., Shiratori-Hayashi, M., Kohro, Y., Tozaki-Saitoh, H. & Tsuda, M., 1 2020, : : Journal of Allergy and Clinical Immunology. 145, 1, p. 183-191.e10

研究成果: ジャーナルへの寄稿記事

Bombesin Receptors
Gastrin-Releasing Peptide
Neurons
Posterior Horn Cells
Astrocytes
2019
1 引用 (Scopus)

2-Oxo-histidine-containing dipeptides are functional oxidation products

Ihara, H., Kakihana, Y., Yamakage, A., Kai, K., Shibata, T., Nishida, M., Kenichi, Y. & Uchida, K., 1 1 2019, : : Journal of Biological Chemistry. 294, 4, p. 1279-1289 11 p.

研究成果: ジャーナルへの寄稿記事

Carnosine
Dipeptides
Histidine
Oxidation
Antioxidants

A Convenient Preparation Method for Benzophenone Imine Catalyzed by Tetrabutylammonium Fluoride

Kondo, Y., Morisaki, K., Hirazawa, Y., Morimoto, H. & Ohshima, T., 8 16 2019, : : Organic Process Research and Development. 23, 8, p. 1718-1724 7 p.

研究成果: ジャーナルへの寄稿記事

Imines
imines
fluorides
preparation
synthesis

A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats

Shimizu, Y., Yanobu-Takanashi, R., Nakano, K., Hamase, K., Shimizu, T. & Okamura, T., 2 13 2019, : : Mammalian Genome. 30, 1-2, p. 23-33 11 p.

研究成果: ジャーナルへの寄稿記事

Cystine
Kidney
Glucose
Cystinosis
Genes

Alginate immobilization of Morus alba L. cell suspension cultures improved the accumulation and secretion of stilbenoids

Inyai, C., Boonsnongcheep, P., Komaikul, J., Sritularak, B., Tanaka, H. & Putalun, W., 1 30 2019, : : Bioprocess and Biosystems Engineering. 42, 1, p. 131-141 11 p.

研究成果: ジャーナルへの寄稿記事

Morus
Alginate
Resveratrol
Immobilized Cells
Immobilization

Alpha-mangostin ameliorates bleomycin-induced pulmonary fibrosis in mice partly through activating adenosine 5′-monophosphate-activated protein kinase

Li, R. S., Xu, G. H., Cao, J., Liu, B., Xie, H. F., Ishii, Y. & Zhang, C. F., 1 1 2019, : : Frontiers in Pharmacology. 10, 1305.

研究成果: ジャーナルへの寄稿記事

公開
Pulmonary Fibrosis
Bleomycin
Adenosine Monophosphate
Protein Kinases
Lung

A method to induce hen egg lysozyme-specific humoral immune tolerance in mice by pre-exposition with the protein's oligomers

Ohkuri, T., Yuge, N., Sato, K. & Ueda, T., 12 1 2019, : : Biochemistry and Biophysics Reports. 20, 100679.

研究成果: ジャーナルへの寄稿記事

公開
Immune Tolerance
Oligomers
Antibodies
Anti-Idiotypic Antibodies
Proteins
1 引用 (Scopus)

Ammonium Salt-Accelerated Hydrazinolysis of Unactivated Amides: Mechanistic Investigation and Application to a Microwave Flow Process

Noshita, M., Shimizu, Y., Morimoto, H., Akai, S., Hamashima, Y., Ohneda, N., Odajima, H. & Ohshima, T., 4 19 2019, : : Organic Process Research and Development. 23, 4, p. 588-594 7 p.

研究成果: ジャーナルへの寄稿記事

hydrazine
Ammonium Compounds
Amides
amides
Salts

A new approach to prevent the chemotherapy-induced peripheral neuropathy

Kawashiri, T., 1 1 2019, : : Folia Pharmacologica Japonica. 153, 4, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Peripheral Nervous System Diseases
Drug Therapy
1 引用 (Scopus)

An indirect competitive enzyme-linked immunosorbent assay toward the standardization of Pueraria candollei based on its unique isoflavonoid, kwakhurin

Yusakul, G., Togita, R., Minami, K., Chanpokapaiboon, K., Juengwatanatrakul, T., Putalun, W., Tanaka, H., Sakamoto, S. & Morimoto, S., 3 2019, : : Fitoterapia. 133, p. 23-28 6 p.

研究成果: ジャーナルへの寄稿記事

Pueraria
Enzyme-Linked Immunosorbent Assay
Estrogen Replacement Therapy
Bovine Serum Albumin
Limit of Detection

A novel mode of DnaA-DnaA interaction promotes ADP dissociation for reactivation of replication initiation activity

Sugiyama, R., Kasho, K., Miyoshi, K., Ozaki, S., Kagawa, W., Kurumizaka, H. & Katayama, T., 12 2 2019, : : Nucleic acids research. 47, 21, p. 11209-11224 16 p.

研究成果: ジャーナルへの寄稿記事

公開
Adenosine Diphosphate
Protein Subunits
Adenosine Triphosphate
Structural Models
Cell Cycle

Anti-allergic activity of polyphenolic compounds isolated from olive mill wastes

Mwakalukwa, R., Ashour, A., Amen, Y., Niwa, Y., Tamrakar, S., Miyamoto, T. & Shimizu, K., 7 1 2019, : : Journal of Functional Foods. 58, p. 207-217 11 p.

研究成果: ジャーナルへの寄稿記事

Anti-Allergic Agents
Olea
Inhibitory Concentration 50
polyphenols
Calcium Channels

Ascorbic acid insufficiency impairs spatial memory formation in juvenile AKR1A-knockout mice

Kurihara, K., Homma, T., Kobayashi, S., Shichiri, M., Fujiwara, H., Fujii, S., Yamada, K., Nakane, M., Kawamae, K. & Fujii, J., 1 1 2019, : : Journal of Clinical Biochemistry and Nutrition. 65, 3, p. 209-216 8 p.

研究成果: ジャーナルへの寄稿記事

Knockout Mice
Ascorbic Acid
Data storage equipment
Spatial Memory
Weaning

Bif-1/Endophilin B1/SH3GLB1 regulates bone homeostasis

Touyama, K., Khan, M., Aoki, K., Matsuda, M., Hiura, F., Takakura, N., Matsubara, T., Harada, Y., Hirohashi, Y., Tamura, Y., Gao, J., Mori, K., Kokabu, S., Yasuda, H., Fujita, Y., Watanabe, K., Takahashi, Y., Maki, K. & Jimi, E., 11 1 2019, : : Journal of Cellular Biochemistry. 120, 11, p. 18793-18804 12 p.

研究成果: ジャーナルへの寄稿記事

Bone
Homeostasis
Bone and Bones
Osteoclasts
Osteogenesis

Characterization of α-synuclein N-terminal domain as a novel cellular phosphatidic acid sensor

Yamada, H., Mizuno, S., Honda, S., Takahashi, D. & Sakane, F., 1 1 2019, (受理済み/印刷中) : : FEBS Journal.

研究成果: ジャーナルへの寄稿記事

Synucleins
Phosphatidic Acids
Sensors
Diacylglycerol Kinase
Cell membranes

Chronopharmacological strategies focused on chrono-drug discovery

Ohdo, S., Satoru, K. & Naoya, M., 10 1 2019, : : Pharmacology and Therapeutics. 202, p. 72-90 19 p.

研究成果: ジャーナルへの寄稿評論記事

Drug Discovery
Periodicity
Chronic Renal Insufficiency
Pharmaceutical Preparations
Neoplastic Stem Cells
1 引用 (Scopus)

Circulating messenger for neuroprotection induced by molecular hydrogen

Noda, M., Uemura, Y., Yoshii, Y., Horita, T., Takemi, S., Sakata, I. & Sakai, T., 1 1 2019, : : Canadian journal of physiology and pharmacology. 97, 10, p. 909-915 7 p.

研究成果: ジャーナルへの寄稿評論記事

Ghrelin
Hydrogen
Drinking Water
Oxidative Stress
Ghrelin Receptor
6 引用 (Scopus)

Clinical Pharmacokinetics of Anaplastic Lymphoma Kinase Inhibitors in Non-Small-Cell Lung Cancer

Hirota, T., Muraki, S. & Ieiri, I., 4 4 2019, : : Clinical Pharmacokinetics. 58, 4, p. 403-420 18 p.

研究成果: ジャーナルへの寄稿評論記事

Non-Small Cell Lung Carcinoma
Pharmacokinetics
Pharmaceutical Preparations
Cytochrome P-450 Enzyme System
Cytochrome P-450 CYP3A

Cytotoxicity of trifluridine correlates with the thymidine kinase 1 expression level

Kataoka, Y., Iimori, M., Niimi, S., Tsukihara, H., Wakasa, T., Saeki, H., Oki, E., Maehara, Y. & Kitao, H., 12 1 2019, : : Scientific reports. 9, 1, 7964.

研究成果: ジャーナルへの寄稿記事

公開
Trifluridine
thymidine kinase 1
Colorectal Neoplasms
DNA
Clustered Regularly Interspaced Short Palindromic Repeats
1 引用 (Scopus)

Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload

Nishimura, A., Shimoda, K., Tanaka, T., Toyama, T., Nishiyama, K., Shinkai, Y., Numaga-Tomita, T., Yamazaki, D., Kanda, Y., Akaike, T., Kumagai, Y. & Nishida, M., 1 1 2019, : : Science Signaling. 12, 587, eaaw1920.

研究成果: ジャーナルへの寄稿記事

Filamins
Hemodynamics
Cardiac Myocytes
Oxidation-Reduction
Rats

Development of a simple and rapid method for the detection of isomiroestrol in Pueraria candollei by an immunochromatographic strip test

Chaingam, J., Kitisripanya, T., Krittanai, S., Sakamoto, S., Tanaka, H. & Putalun, W., 6 14 2019, : : Journal of Natural Medicines. 73, 3, p. 577-583 7 p.

研究成果: ジャーナルへの寄稿記事

Pueraria
Standardization
Benzopyrans
Gold Colloid
Immunosorbents

Development of novel functional molecules targeting DNA and RNA

Sasaki, S., 1 1 2019, : : Chemical and Pharmaceutical Bulletin. 67, 6, p. 505-518 14 p.

研究成果: ジャーナルへの寄稿評論記事

公開
Nucleosides
Oligonucleotides
Artificial Receptors
RNA
Molecules
4 引用 (Scopus)

Development of Turn-On Probes for Acids Triggered by Aromaticity Enhancement Using Tricyclic Amidine Derivatives

Matsumoto, S., Fuchi, Y., Usui, K., Hirai, G. & Karasawa, S., 6 7 2019, : : Journal of Organic Chemistry. 84, 11, p. 6612-6622 11 p.

研究成果: ジャーナルへの寄稿記事

Amidines
Fluorescence
Protonation
Quantum yield
Derivatives
1 引用 (Scopus)
公開
oxaliplatin
Peripheral Nervous System Diseases
Rodentia
Hyperalgesia
Neoplasms

Donepezil ameliorates oxaliplatin-induced peripheral neuropathy via a neuroprotective effect

kawashiri, T., Shimizu, S., Shigematsu, N., Kobayashi, D. & Shimazoe, T., 7 1 2019, : : Journal of Pharmacological Sciences. 140, 3, p. 291-294 4 p.

研究成果: ジャーナルへの寄稿記事

公開
oxaliplatin
Neuroprotective Agents
Peripheral Nervous System Diseases
Cultured Cells
Nerve Degeneration
1 引用 (Scopus)

Dosing Time-Dependent Changes in the Anti-tumor Effect of xCT Inhibitor Erastin in Human Breast Cancer Xenograft Mice

Shiromizu, S., Yamauchi, T., Kusunose, N., Matsunaga, N., Koyanagi, S. & Ohdo, S., 1 1 2019, : : Biological and Pharmaceutical Bulletin. 42, 11, p. 1921-1925 5 p.

研究成果: ジャーナルへの寄稿記事

公開
Heterografts
Breast Neoplasms
Neoplasms
Cysteine
Cystine
2 引用 (Scopus)

D -Serine reflects kidney function and diseases

Hesaka, A., Sakai, S., Hamase, K., Ikeda, T., Matsui, R., Mita, M., Horio, M., Isaka, Y. & Kimura, T., 12 1 2019, : : Scientific reports. 9, 1, 5104.

研究成果: ジャーナルへの寄稿記事

公開
Kidney Diseases
Serine
Chronic Renal Insufficiency
Kidney
Amino Acids

Effect of digital labels on electronic medical records for reducing the use of benzodiazepine receptor agonists

Shin, K., Kobayashi, D., Kawashiri, T., Ikari, K., Mitsuyasu, H., Murakami, T., Tsutsumi, K., Kanazawa, Y., Kamimura, H. & Shimazoe, T., 1 1 2019, : : Yakugaku Zasshi. 139, 11, p. 1449-1456 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Electronic Health Records
GABA-A Receptors
Prescriptions
Pharmacists
Delirium
6 引用 (Scopus)

Effect of OATP1B1 genotypes on plasma concentrations of endogenous OATP1B1 substrates and drugs, and their association in healthy volunteers

Mori, D., Kashihara, Y., Yoshikado, T., Kimura, M., Hirota, T., Matsuki, S., Maeda, K., Irie, S., Ieiri, I., Sugiyama, Y. & Kusuhara, H., 2 2019, : : Drug metabolism and pharmacokinetics. 34, 1, p. 78-86 9 p.

研究成果: ジャーナルへの寄稿記事

Sulfates
Healthy Volunteers
Genotype
fluvastatin
Pharmaceutical Preparations

Effects of magnesium oxide on pharmacokinetics of L-dopa/carbidopa and assessment of pharmacodynamic changes by a model-based simulation

Kashihara, Y., Terao, Y., Yoda, K., Hirota, T., Kubota, T., Kimura, M., Matsuki, S., Hirakawa, M., Irie, S. & Ieiri, I., 3 6 2019, : : European Journal of Clinical Pharmacology. 75, 3, p. 351-361 11 p.

研究成果: ジャーナルへの寄稿記事

Magnesium Oxide
Carbidopa
Levodopa
Pharmacokinetics
Meta-Analysis

Effects of Substituents on the Properties of Metal-Free MRI Contrast Agents

Shiraishi, R., Kaneko, T., Usui, K., Naganuma, T., Iizuka, N., Morishita, K., Kobayashi, S., Fuchi, Y., Matsuoka, Y., Hirai, G., Yamada, K. I. & Karasawa, S., 12 10 2019, : : ACS Omega. 4, 24, p. 20715-20723 9 p.

研究成果: ジャーナルへの寄稿記事

公開
Magnetic resonance
Contrast Media
Gadolinium
Metals
Imaging techniques
公開
DNA-Directed DNA Polymerase
DNA Polymerase I
Adenosine
Nucleotides
Derivatives
3 引用 (Scopus)

Efficacy of DPP-4 inhibitors, GLP-1 analogues, and SGLT2 inhibitors as add-ons to metformin monotherapy in T2DM patients: a model-based meta-analysis

Inoue, H., Tamaki, Y., Kashihara, Y., Muraki, S., Kakara, M., Hirota, T. & Ieiri, I., 2 2019, : : British journal of clinical pharmacology. 85, 2, p. 393-402 10 p.

研究成果: ジャーナルへの寄稿記事

Glucagon-Like Peptide 1
Metformin
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Meta-Analysis

Electron Microscopic Detection of Single Membrane Proteins by a Specific Chemical Labeling

Tabata, S., Jevtic, M., Kurashige, N., Fuchida, H., Kido, M., Tani, K., Zenmyo, N., Uchinomiya, S., Harada, H., Itakura, M., Hamachi, I., Shigemoto, R. & Ojida, A., 12 20 2019, : : iScience. 22, p. 256-268 13 p.

研究成果: ジャーナルへの寄稿記事

公開
Labeling
Membrane Proteins
Electrons
Electron microscopy
Proteins

Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory

Li, R. S., Fukumori, R., Takeda, T., Song, Y., Morimoto, S., Kikura-Hanajiri, R., Yamaguchi, T., Watanabe, K., Aritake, K., Tanaka, Y., Yamada, H., Yamamoto, T. & Ishii, Y., 7 3 2019, : : Scientific reports. 9, 1, 1 p., 9621.

研究成果: ジャーナルへの寄稿記事

公開
Endocannabinoids
Cannabinoids
Learning
Brain-Derived Neurotrophic Factor
Brain
1 引用 (Scopus)

Elucidation of N1-methyladenosine as a potential surrogate biomarker for drug interaction studies involving renal organic cation transporters

Miyake, T., Mizuno, T., Takehara, I., Mochizuki, T., Kimura, M., Matsuki, S., Irie, S., Watanabe, N., Kato, Y., Ieiri, I., Maeda, K., Ando, O. & Kusuhara, H., 1 1 2019, : : Drug Metabolism and Disposition. 47, 11, p. 1270-1280 11 p.

研究成果: ジャーナルへの寄稿記事

Drug Interactions
Cations
Biomarkers
Kidney
Pharmaceutical Preparations

Enhancement of saccharothriolide production and discovery of a new metabolite, saccharothriolide C 2 , by combined-culture of Saccharothrix sp. and Tsukamurella pulmonis

Jiang, Y., Lu, S., Hirai, G., Kato, T., Onaka, H. & Kakeya, H., 4 11 2019, : : Tetrahedron Letters. 60, 15, p. 1072-1074 3 p.

研究成果: ジャーナルへの寄稿記事

Mycolic Acids
Metabolites
Bacteria
1 引用 (Scopus)
公開
Escherichia coli Proteins
Cell Division
Proteins
AT Rich Sequence
DNA Polymerase III

Estradiol regulation of P-glycoprotein expression in mouse kidney and human tubular epithelial cells, implication for renal clearance of drugs

Kanado, Y., Tsurudome, Y., Omata, Y., Yasukochi, S., Kusunose, N., Akamine, T., Matsunaga, N., Koyanagi, S. & Ohdo, S., 11 12 2019, : : Biochemical and Biophysical Research Communications. 519, 3, p. 613-619 7 p.

研究成果: ジャーナルへの寄稿記事

P-Glycoprotein
Estradiol
Digoxin
Epithelial Cells
Kidney

Evaluation of pharmacist-led interview before doctor examination for psychiatry outpatients

Shin, K., Kobayashi, D., kawashiri, T., Ushijima, Y., Umeda, Y., Kanazawa, Y., Kamimura, H. & Shimazoe, T., 1 1 2019, : : Yakugaku Zasshi. 139, 2, p. 317-325 9 p.

研究成果: ジャーナルへの寄稿コメント/討論

Pharmacists
Psychiatry
Outpatients
Interviews
Hospital Psychiatric Department