研究成果 1976 2019

1976
43 引用 (Scopus)

Purification and Characterization of Microsomal and Lysosomal β‐Glucuronidase from Rat Liver by Use of Immunoaffinity Chromatography

HIMENO, M., NISHIMURA, Y., TSUJI, H. & KATO, K., 11 1976, : : European Journal of Biochemistry. 70, 2, p. 349-359 11 p.

研究成果: ジャーナルへの寄稿記事

Glucuronidase
Chromatography
Liver
Purification
Rats
1978
17 引用 (Scopus)

The synthesis of rat liver lysosomes: III. chemical composition of microsomal and lysosomal β-glucuronidases purified from rat liver

Himeno, M., Nishimura, Y., Takahashi, K. & Kato, K., 1 1 1978, : : Journal of biochemistry. 83, 2, p. 511-518 8 p.

研究成果: ジャーナルへの寄稿記事

Glucuronidase
Lysosomes
Liver
Rats
N-Acetylneuraminic Acid
1980
4 引用 (Scopus)

Studies on the αL-iduronidase activity of β-glucuronidase preparations from bovine liver, rat liver, and rat preputial gland

Kosaka, H., Isemura, M., Ono, T., Nishimura, Y. & Kato, K., 7 1 1980, : : Journal of biochemistry. 88, 1, p. 69-75 7 p.

研究成果: ジャーナルへの寄稿記事

Iduronidase
Glucuronidase
Liver
Rats
Hydrolysis
1981
11 引用 (Scopus)

Cannabis. XIV. Two New Propyl Cannabinoids, Cannabicyclovarin and Δ7-cis-Iso-tetrahydrocannabivarin, from Thai Cannabis

Shoyama, Y., Morimoto, S. & Nishioka, I., 1 1 1981, : : Chemical and Pharmaceutical Bulletin. 29, 12, p. 3720-3723 4 p.

研究成果: ジャーナルへの寄稿記事

Cannabinoids
Cannabis
Skeleton
24 引用 (Scopus)

Comparative studies of asparagine-linked oligosaccharide structures of rat liver microsomal and lysosomal β-glucuronidases

Mizuochi, T., Nishimura, Y., Kato, K. & Kobata, A., 1 1 1981, : : Archives of Biochemistry and Biophysics. 209, 1, p. 298-303 6 p.

研究成果: ジャーナルへの寄稿記事

Asparagine
Glucuronidase
Oligosaccharides
Sugars
Liver
1982
43 引用 (Scopus)

Guest-induced conformational change of β-cyclodextrin capped with an environmentally sensitive chromophore

Fujita, K., Ueda, T., Imoto, T., Tabushi, I., Toh, N. & Koga, T., 3 1982, : : Bioorganic Chemistry. 11, 1, p. 72-84 13 p.

研究成果: ジャーナルへの寄稿記事

Cyclodextrins
Chromophores
Circular Dichroism
Nuclear magnetic resonance
67 引用 (Scopus)

Polymeric Inclusion Compound Derived from β-Cyclodextrin

Hirotsu, K., Higuchi, T., Fujita, K., Ueda, T., Shinoda, A., Imoto, T. & Tabushi, I., 1 1 1982, : : Journal of Organic Chemistry. 47, 6, p. 1143-1144 2 p.

研究成果: ジャーナルへの寄稿記事

betadex
12 引用 (Scopus)

Selective recognition of alkanoates by a β-cyclodextrin flexibly capped with a chromophore

Fujita, K., Ueda, T., Imoto, T., Tabushi, I., Toh, N. & Koga, T., 1 1 1982, : : Bioorganic Chemistry. 11, 2, p. 108-114 7 p.

研究成果: ジャーナルへの寄稿記事

Cyclodextrins
Chromophores
Sodium
Circular Dichroism
Spectrum Analysis
1983
4 引用 (Scopus)

Cannabis. XV. preparation and stability of Δ9-tetrahydrocannabinol-β-cyclodextrin inclusion complex

Shoyama, Y., Morimoto, S. & Nishioka, I., 1 1 1983, : : Journal of Natural Products. 46, 5, p. 633-637 5 p.

研究成果: ジャーナルへの寄稿記事

Dronabinol
Cyclodextrins
Cannabis
Drug Delivery Systems
Oxygen
4 引用 (Scopus)

Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin

Fujita, K., Ueda, T., Matsunaga, A. & Imoto, T., 1 1 1983, : : NIPPON KAGAKU KAISHI. 1983, 2, p. 207-213 7 p.

研究成果: ジャーナルへの寄稿記事

Cyclodextrins
Dichroism
Nuclear magnetic resonance
Molecules

Practical application results of the Hirose's simple microdiffusion method for determining alcohol of body fluids

Noda, M., Uehori, R., Makizumi, S. & Hirose, H., 1 1 1983, : : Fukuoka Acta Medica. 74, 3, p. 131-136 6 p.

研究成果: ジャーナルへの寄稿記事

Forensic Medicine
Body Fluids
Cadaver
Ethanol
Alcohols
87 引用 (Scopus)
Catechin
Tannins
1985
2 引用 (Scopus)

Acute myocardial infarction following asymptomatic ST elevation despite diltiazem therapy

Egashira, K., Araki, H., Koiwaya, Y., Takeshita, A. & Nakamura, M., 2 1985, : : American heart journal. 109, 2, p. 379-380 2 p.

研究成果: ジャーナルへの寄稿記事

Coronary Vasospasm
Diltiazem
Angina Pectoris
Myocardial Infarction
Therapeutics
36 引用 (Scopus)
Muramidase
Histidine
Lysine
Derivatives
Stabilization
1 引用 (Scopus)

Behavioral and electroencephalographic effects of lormetazepam

Ueki, S., Watanabe, S., Fujiwara, M., Yamamoto, T., Shibata, S., Shibata, K., Ohta, H., Sakurai, Y., Iwasaki, K., Liou, S. Y., Yamashita, K., Shimazoe, T. & Yamaji, T., 1 1 1985, : : Folia Pharmacologica Japonica. 86, 2, p. 145-163 19 p.

研究成果: ジャーナルへの寄稿記事

Flurazepam
Diazepam
Nitrazepam
Electric Stimulation
Electroencephalography
7 引用 (Scopus)

Behavioral pharmacology of amantadine with special references to the effect on abnormal behavior in mice and rats

Fujiwara, M., Sakurai, Y., Kiyota, Y., Shimazoe, T., Hisashi, O., Shibata, S. & Ueki, S., 1 1 1985, : : Folia Pharmacologica Japonica. 85, 4, p. 259-274 16 p.

研究成果: ジャーナルへの寄稿記事

Amantadine
Pharmacology
Imipramine
Catalepsy
Dronabinol
16 引用 (Scopus)
Bearings (structural)
Crown Ethers
Biomimetics
Sulfhydryl Compounds
Esters
39 引用 (Scopus)

Isolation and Characterization of 101-β-Lysozyme That Possesses the β-Aspartyl Sequence at Aspartic Acid-101

Yamada, H., Ueda, T., Kuroki, R., Fukumura, T., Yasukochi, T., Hirabayashi, T., Fujita, K. & Imoto, T., 12 1 1985, : : Biochemistry. 24, 27, p. 7953-7959 7 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Aspartic Acid
Biochemistry
Diatomaceous Earth
Derivatives
15 引用 (Scopus)
Anthracenes
Cyclopentanes
Cycloaddition
Molecular orbitals
Irradiation
26 引用 (Scopus)

Studies on Prodrugs. IV. Preparation and Characterization of N-(5-Substituted 2-oxo-l,3-dioxol-4-yl)methyl Norfloxacin

Sakamoto, F., Ikeda, S., Kondo, H. & Tsukamoto, G., 1 1 1985, : : Chemical and Pharmaceutical Bulletin. 33, 11, p. 4870-4877 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Norfloxacin
Prodrugs
Blood
Amines
Oral Administration
30 引用 (Scopus)

Tannins and Related Compounds. Proanthocyanidins with a Doubly Linked Unit from the Root Bark of Cinnamomum sieboldii Meisner

Morimoto, S., Nonaka, G. I. & Nishioka, I., 1 1 1985, : : Chemical and Pharmaceutical Bulletin. 33, 10, p. 4338-4345 8 p.

研究成果: ジャーナルへの寄稿記事

Cinnamomum
Proanthocyanidins
Catechin
Tannins
Lauraceae
61 引用 (Scopus)
Lindera
Cinnamomum aromaticum
Catechin
Tannins
Cinnamomum

The Pharmacokinetics of Salicylic Acid Following Single and Repeated Administration of Slow-release Formulations of Aspirin in Healthy Japanese Volunteers and the Effect of Dosing Time

Yanaihara, H., Murakami, K., Fukuda, T., Nakano, S., Ohdo, S., Takaoka, N. & Ogawa, N., 1 1 1985, : : Japanese Journal of Clinical Pharmacology and Therapeutics. 16, 4, p. 759-768 10 p.

研究成果: ジャーナルへの寄稿記事

Salicylic Acid
Aspirin
Healthy Volunteers
Pharmacokinetics
Enteric-Coated Tablets
23 引用 (Scopus)

Δ9-tetrahydrocannabinol elicited ipsilateral circling behavior in rats with unilateral nigral lesion

Sakurai, Y., Ohta, H., Shimazoe, T., Kataoka, Y., Fujiwara, M. & Ueki, S., 12 9 1985, : : Life Sciences. 37, 23, p. 2181-2185 5 p.

研究成果: ジャーナルへの寄稿記事

Dronabinol
Substantia Nigra
Rats
Oxidopamine
Dopaminergic Neurons
1986
17 引用 (Scopus)

Elaeocarpusin, A Proto-Type of Geraniin From Geranium Thunbergii

Nonaka, G., Morimoto, S. & Nishioka, I., 1 1 1986, : : Chemical and Pharmaceutical Bulletin. 34, 2, p. 941-943 3 p.

研究成果: ジャーナルへの寄稿記事

Geranium
Hydrolyzable Tannins
Quinic Acid
Dehydroascorbic Acid
Metabolism
73 引用 (Scopus)

Histamine-induced coronary spasm in regions of intimal thickening in miniature pigs: Roles of serum cholesterol and spontaneous or induced intimal thickening

Egashira, K., Tomoike, H., Yamamoto, Y., Yamada, A., Hayashi, Y. & Nakamura, M., 1 1 1986, : : Circulation. 74, 4, p. 826-837 12 p.

研究成果: ジャーナルへの寄稿記事

Tunica Intima
Spasm
Histamine
Swine
Cholesterol
38 引用 (Scopus)

Isolation and structures of aplykurodins a and b, two new isoprenoids from the marine mollusk aplysia kurodai

Miyamoto, T., Higuchi, R., Komori, T., Fujioka, T. & Mihashi, K., 1986, : : Tetrahedron Letters. 27, 10, p. 1153-1156 4 p.

研究成果: ジャーナルへの寄稿記事

Aplysia
Mollusca
Terpenes
X-Rays
X rays
29 引用 (Scopus)
Cinnamomum aromaticum
Proanthocyanidins
Tannins
Glucosides
varespladib methyl
101 引用 (Scopus)
Cinnamomum aromaticum
Cassia
Proanthocyanidins
Catechin
Tannins
80 引用 (Scopus)

Unfolding rates of globular proteins determined by kinetics of proteolysis

Imoto, T., Yamada, H. & Ueda, T., 8 20 1986, : : Journal of Molecular Biology. 190, 4, p. 647-649 3 p.

研究成果: ジャーナルへの寄稿記事

Proteolysis
Digestion
Peptide Hydrolases
Muramidase
Pancreatic Ribonuclease
1987
10 引用 (Scopus)

A new approach to linear tetracycles via Michael reactions of quinizarinquinone with O-silylated ketene acetals

Hayakawa, K., Aso, M. & Kanematsu, K., 12 1 1987, : : Journal of the Chemical Society, Chemical Communications. 2, p. 102-104 3 p.

研究成果: ジャーナルへの寄稿記事

Lewis Acids
Acetals
Cyclization
Acids
ketene
19 引用 (Scopus)

A new forced swimming test for the evaluation of antidepressants in rats by recording vibration of a water tank

Shimazoe, T., Shibata, S. & Ueki, S., 1 1 1987, : : journal of pharmacobio-dynamics. 10, 11, p. 639-643 5 p.

研究成果: ジャーナルへの寄稿記事

Locomotion
Vibration
Antidepressive Agents
Water
Nomifensine
56 引用 (Scopus)
Muscle Spasticity
Vascular Smooth Muscle
Histamine
Endothelium
Swine
16 引用 (Scopus)

Behavioral and Electroencephalographic Effects of Zopiclone, a Cyclopyrrolone Derivative

Ueki, S., Watanabe, S., Yamamoto, T., Kataoka, Y., Shibata, S., Shibata, K., Ohta, H., Shimazoe, T. & Kawamoto, H., 1 1 1987, : : the japanese journal of pharmacology. 43, 3, p. 309-326 18 p.

研究成果: ジャーナルへの寄稿記事

zopiclone
Diazepam
Flurazepam
Nitrazepam
Electroencephalography
6 引用 (Scopus)

Highly controlled carbodiimide reaction for the modification of lysozyme. Modification of leu129 or asp119

Ueda, T., Yamada, H. & Imoto, T., 6 1 1987, : : Protein Engineering, Design and Selection. 1, 3, p. 189-193 5 p.

研究成果: ジャーナルへの寄稿記事

Carbodiimides
Muramidase
Enzymes
Salts
Glucosamine
36 引用 (Scopus)
Cathepsin D
Chemical activation
Processing
Biosynthesis
Immunoblotting
26 引用 (Scopus)

Intracellular transport and processing of lysosomal cathepsin B

Nishimura, Y. & Kato, K., 10 14 1987, : : Biochemical and Biophysical Research Communications. 148, 1, p. 254-259 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin B
Lysosomes
Processing
Subcellular Fractions
Golgi Apparatus
27 引用 (Scopus)

Intracellular transport and processing of lysosomal cathepsin H

Nishimura, Y. & Kato, K., 10 14 1987, : : Biochemical and Biophysical Research Communications. 148, 1, p. 329-334 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Lysosomes
Subcellular Fractions
Golgi Apparatus
Processing
22 引用 (Scopus)

In vitro biosynthesis of the lysosomal cathepsin H

Nishimura, Y. & Kato, K., 7 15 1987, : : Biochemical and Biophysical Research Communications. 146, 1, p. 159-164 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Biosynthesis
Enzyme Precursors
Membranes
Polyribosomes
32 引用 (Scopus)
Leukotriene D4
Leukotriene C4
Constriction
Coronary Vessels
Electrocardiography
15 引用 (Scopus)

Long-Term Prognosis of Vasospastic Angina without Significant Atherosclerotic Coronary Artery Disease

Egashira, K., Kikuchi, Y., Sagara, T., Sugihara, M. & Nakamura, M., 1 1 1987, : : japanese heart journal. 28, 6, p. 841-849 9 p.

研究成果: ジャーナルへの寄稿記事

Coronary Artery Disease
Calcium
Sudden Death
Myocardial Infarction
Atrioventricular Block
10 引用 (Scopus)

Modifications of stability and function of lysozyme

Imoto, T., Yamada, H., Okazaki, K., Ueda, T., Kuroki, R. & Yasukochi, T., 4 1 1987, : : Journal of Protein Chemistry. 6, 2, p. 95-107 13 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Enzymes
Conformations
Catalytic Domain
Proteins
28 引用 (Scopus)

Pathogenesis of coronary artery spasm in miniature swine with regional intimal thickening after balloon denudation

Yamamoto, Y., Tomoike, H., Egashira, K., Kobayashi, T., Kawasaki, T. & Nakamura, M., 1 1 1987, : : Circulation research. 60, 1, p. 113-121 9 p.

研究成果: ジャーナルへの寄稿記事

Tunica Intima
Miniature Swine
Spasm
Histamine
Coronary Vessels
5 引用 (Scopus)

pH Dependence of Individual Tryptophan N-1 Hydrogen Exchange Rates in Lysozyme and Its Chemically Modified Derivatives

Endo, T., Ueda, T., Yamada, H. & Imoto, T., 1 1 1987, : : Biochemistry. 26, 7, p. 1838-1845 8 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Tryptophan
Hydrogen
Derivatives
Protein Denaturation
27 引用 (Scopus)

Point mutation of alanine (31) to valine prohibits the folding of reduced lysozyme by sulfhydryl-disulfide interchange

Imoto, T., Yamada, H., Yasukochi, T., Yamada, E., Ito, Y., Ueda, T., Nagatani, H., Miki, T. & Horiuchi, T., 8 1 1987, : : Protein Engineering, Design and Selection. 1, 4, p. 333-338 6 p.

研究成果: ジャーナルへの寄稿記事

Valine
Interchanges
Muramidase
Point Mutation
Disulfides
1 引用 (Scopus)

Prompt relief of vasospastic angina by calcium antagonists

Egashira, K., Araki, H., Tomoike, H., Takeshita, A. & Nakamura, M., 9 30 1987, : : International Journal of Clinical Pharmacology Therapy and Toxicology. 25, 4, p. 175-177 3 p.

研究成果: ジャーナルへの寄稿記事

Variant Angina Pectoris
Diltiazem
Nitroglycerin
Calcium Channel Blockers
Electrocardiography
5 引用 (Scopus)

Prostanoids, Coronary Circulation and Coronary Artery Spasm in Open Chest Dogs and Miniature Pigs

Egashira, K., Shimokawa, H., Tomoike, H. & Nakamura, M., 1 1 1987, : : JAPANESE CIRCULATION JOURNAL. 51, 4, p. 459-461 3 p.

研究成果: ジャーナルへの寄稿記事

Coronary Circulation
Spasm
Prostaglandins
Coronary Vessels
Swine
5 引用 (Scopus)

Screening of volatile compounds present in human blood using retention indices in gas chromatography

Uehori, R., Nagata, T., Kimura, K., Kudo, K. & Noda, M., 1987, : : Journal of Chromatography A. 411, C, p. 251-257 7 p.

研究成果: ジャーナルへの寄稿記事

Gas chromatography
Gas Chromatography
Screening
Blood
Flame Ionization
38 引用 (Scopus)

Tannins and Related Compounds. L.1) Structures of Proanthocyanidin A-l and Related Compounds

Nonaka, G. I., Morimoto, S., Nishioka, I., Kinjo, J. E. & Nohara, T., 1 1 1987, : : Chemical and Pharmaceutical Bulletin. 35, 1, p. 149-155 7 p.

研究成果: ジャーナルへの寄稿記事

Tannins
Proanthocyanidins
proanthocyanidin
proanthocyanidin A1
53 引用 (Scopus)

Tannins and Related Compounds. LIX.1)Aesculitannins, Novel Proanthocyanidins with Doubly-Bonded Structures from Aesculus hippocastanum L.

Morimoto, S., Nonaka, G. I. & Nishioka, I., 1 1 1987, : : Chemical and Pharmaceutical Bulletin. 35, 12, p. 4717-4729 13 p.

研究成果: ジャーナルへの寄稿記事

Aesculus
Proanthocyanidins
Catechin
Tannins
varespladib methyl