研究成果 1976 2020

7 引用 (Scopus)

Abnormalities of cardiac sympathetic neuronal and left ventricular function in chronic mitral regurgitation: Assessment by iodine-123 metaiodobenzylguanidine scintigraphy

Tsutsui, H., Ando -i., S., Kubota, T., Kuroiwa-Matsumoto, M., Egashira, K., Sasaki, M., Kuwabara, Y., Koyanagi, S., Yasui, H. & Takeshita, A., 2 29 1996, : : American Journal of Cardiac Imaging. 10, 1, p. 14-22 9 p.

研究成果: ジャーナルへの寄稿記事

3-Iodobenzylguanidine
Mitral Valve Insufficiency
Left Ventricular Function
Radionuclide Imaging
Iodine
1 引用 (Scopus)

Abnormalities of the serotonergic system in diacylglycerol kinase δ-deficient mouse brain

Lu, Q., Komenoi, S., Usuki, T., Takahashi, D. & Sakane, F., 3 18 2018, : : Biochemical and Biophysical Research Communications. 497, 4, p. 1031-1037 7 p.

研究成果: ジャーナルへの寄稿記事

Diacylglycerol Kinase
Brain
Obsessive-Compulsive Disorder
Knockout Mice
Serotonin

A case of indocyanine green excretion defect worsened during acute hepatitis following sudden deafness

Sakamoto, S., Egashira, K., Koga, S. & Ibayashi, H., 1 1 1988, : : Kanzo. 26, 12, p. 1686-1689 4 p.

研究成果: ジャーナルへの寄稿記事

Sudden Hearing Loss
Indocyanine Green
Hepatitis
Sulfobromophthalein
Otolaryngology
12 引用 (Scopus)

Acceleration of impairment of endothelium-dependent responses under poor runoff conditions in canine autogenous vein grafts

Komori, K., Yamamura, S., Ishida, M., Matsumoto, T., Kuma, S., Eguchi, D., Yonemitsu, Y., Onohara, T. & Sugimachi, K., 1 1 1997, : : European Journal of Vascular and Endovascular Surgery. 14, 6, p. 475-481 7 p.

研究成果: ジャーナルへの寄稿記事

Endothelium
Canidae
Veins
Transplants
Tunica Intima
606 引用 (Scopus)

Accumulation of autophagic vacuoles and cardiomyopathy LAMP-2-deficient mice

Tanaka, Y., Guhde, G., Suter, A., Eskelinen, E. L., Hartmann, D., Lüllmann-Rauch, R., Janssen, P. M. L., Blanz, J., Von Figura, K. & Saftig, P., 8 24 2000, : : Nature. 406, 6798, p. 902-906 5 p.

研究成果: ジャーナルへの寄稿記事

Lysosome-Associated Membrane Glycoproteins
Vacuoles
Cardiomyopathies
Protein Deficiency
Glycogen Storage Disease Type IIb
Sorbitol
Neuralgia
Sciatic Nerve
Medical problems
Diabetic Neuropathies
30 引用 (Scopus)

Accumulation of β- and γ-synucleins in the ubiquitin carboxyl-terminal hydrolase L1-deficient gad mouse

Wang, Y. L., Takeda, A., Osaka, H., Hara, Y., Furuta, A., Setsuie, R., Sun, Y. J., Kwon, J., Sato, Y., Sakurai, M., Noda, M., Yoshikawa, Y. & Wada, K., 9 3 2004, : : Brain Research. 1019, 1-2, p. 1-9 9 p.

研究成果: ジャーナルへの寄稿記事

Synucleins
Hydrolases
Ubiquitin
Protein Isoforms
Multiple System Atrophy
15 引用 (Scopus)

A chimera of green fluorescent protein with single chain variable fragment antibody against ginsenosides for fluorescence-linked immunosorbent assay

Sakamoto, S., Tanizaki, Y., Pongkitwitoon, B., Tanaka, H. & Morimoto, S., 5 1 2011, : : Protein Expression and Purification. 77, 1, p. 124-130 7 p.

研究成果: ジャーナルへの寄稿記事

Ginsenosides
Single-Chain Antibodies
Immunosorbents
Green Fluorescent Proteins
Fluorescence
26 引用 (Scopus)

A Chronic fatigue syndrome model demonstrates mechanical allodynia and muscular hyperalgesia via spinal microglial activation

Yasui, M., Yoshimura, T., Takeuchi, S., Tokizane, K., Tsuda, M., Inoue, K. & Kiyama, H., 9 2014, : : GLIA. 62, 9, p. 1407-1417 11 p.

研究成果: ジャーナルへの寄稿記事

Chronic Fatigue Syndrome
Hyperalgesia
Pain
Microglia
Minocycline
86 引用 (Scopus)

A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication origin

Ozaki, S., Kawakami, H., Nakamura, K., Fujikawa, N., Kagawa, W., Park, S. Y., Yokoyama, S., Kurumizaka, H. & Katayama, T., 3 28 2008, : : Journal of Biological Chemistry. 283, 13, p. 8351-8362 12 p.

研究成果: ジャーナルへの寄稿記事

Replication Origin
Adenosine Triphosphate
Adenosine Diphosphate
Thermotoga maritima
Eubacterium
14 引用 (Scopus)

A composite resonator assembly suitable for EPR/NMR coregistration imaging

Matsumoto, S., Nagai, M., Yamada, K., Hyodo, F., Yasukawa, K., Muraoka, M., Hirata, H., Ono, M. & Utsumi, H., 4 1 2005, : : Concepts in Magnetic Resonance Part B: Magnetic Resonance Engineering. 25, 1, p. 1-11 11 p.

研究成果: ジャーナルへの寄稿記事

Electron Spin Resonance Spectroscopy
Paramagnetic resonance
Resonators
electron paramagnetic resonance
Magnetic Resonance Spectroscopy

A Convenient Preparation Method for Benzophenone Imine Catalyzed by Tetrabutylammonium Fluoride

Kondo, Y., Morisaki, K., Hirazawa, Y., Morimoto, H. & Ohshima, T., 8 16 2019, : : Organic Process Research and Development. 23, 8, p. 1718-1724 7 p.

研究成果: ジャーナルへの寄稿記事

Imines
imines
fluorides
preparation
synthesis
16 引用 (Scopus)

A coplanar PCB induces a selenium binding protein as a major cytosolic protein in rat liver

Ishii, Y., Hatsumura, M., Ishida, T., Ariyoshi, N. & Oguri, K., 1 1 1996, : : Chemosphere. 32, 3, p. 509-515 7 p.

研究成果: ジャーナルへの寄稿記事

Selenium-Binding Proteins
Polychlorinated Biphenyls
Selenium
Polychlorinated biphenyls
selenium
9 引用 (Scopus)

A critical role of MYC for transformation of human cells by HPV16 E6E7 and oncogenic HRAS

Narisawa-Saito, M., Inagawa, Y., Yoshimatsu, Y., Haga, K., Tanaka, K., Egawa, N., Ohno, S. I., Ichikawa, H., Yugawa, T., Fujita, M. & Kiyono, T., 4 16 2012, : : Carcinogenesis. 33, 4, p. 910-917 8 p.

研究成果: ジャーナルへの寄稿記事

Keratinocytes
Neoplastic Cell Transformation
Sirolimus
Neoplasms
Foreskin
12 引用 (Scopus)

Activation and alteration of base selectivity by metal cations in the functionality-transfer reaction for RNA modification

Onizuka, K., Taniguchi, Y. & Sasaki, S., 8 18 2010, : : Bioconjugate Chemistry. 21, 8, p. 1508-1512 5 p.

研究成果: ジャーナルへの寄稿記事

Guanine
Transfer RNA
RNA
Transition metals
Cations
2 引用 (Scopus)

Activation of a refolded, berberine-specific, single-chain Fv fragment by addition of free berberine

Kim, J. S., Masaki, T., Sirikantaramas, S., Shoyama, Y. & Tanaka, H., 7 1 2006, : : Biotechnology letters. 28, 13, p. 999-1006 8 p.

研究成果: ジャーナルへの寄稿記事

Immunoglobulin Variable Region
Berberine
Single-Chain Antibodies
Assays
Enzymes
24 引用 (Scopus)
Cytosolic Phospholipases A2
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Peripheral Nerve Injuries
Spinal Ganglia
Neurons
110 引用 (Scopus)

Activation of dorsal horn microglia contributes to diabetes-induced tactile allodynia via extracellular signal-regulated protein kinase signaling

Makoto, T., Ueno, H., Kataoka, A., Saitoh, H. & Inoue, K., 3 1 2008, : : GLIA. 56, 4, p. 378-386 9 p.

研究成果: ジャーナルへの寄稿記事

Hyperalgesia
Extracellular Signal-Regulated MAP Kinases
Microglia
Protein Kinases
Streptozocin
6 引用 (Scopus)

Activation of morphine glucuronidation by fatty acyl-CoAs and its plasticity: A comparative study in humans and rodents including chimeric mice carrying human liver

Nurrochmad, A., Ishii, Y., Nakanoh, H., Inoue, T., Horie, T., Sugihara, K., Ohta, S., Taketomi, A., Maehara, Y. & Yamada, H., 1 1 2010, : : Drug metabolism and pharmacokinetics. 25, 3, p. 262-273 12 p.

研究成果: ジャーナルへの寄稿記事

Microsomes
Morphine
Rodentia
Uridine Diphosphate Glucuronic Acid
Liver
80 引用 (Scopus)

Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT

Kataoka, A., Saitoh, H., Koga, Y., Makoto, T. & Inoue, K., 1 1 2009, : : Journal of Neurochemistry. 108, 1, p. 115-125 11 p.

研究成果: ジャーナルへの寄稿記事

Purinergic P2X7 Receptors
NFATC Transcription Factors
CC Chemokines
Transcription Factors
Adenosine Triphosphate
6 引用 (Scopus)

Activation of the FA pathway mediated by phosphorylation and ubiquitination

Ishiai, M., Sato, K., Tomida, J., Kitao, H., Kurumizaka, H. & Takata, M., 10 2017, : : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 803-805, p. 89-95 7 p.

研究成果: ジャーナルへの寄稿評論記事

Fanconi Anemia
Ubiquitination
Phosphorylation
Fanconi Anemia Complementation Group D2 Protein
Bone Marrow Cells
19 引用 (Scopus)
Modifier Genes
Alkylating Agents
Oligonucleotides
Cytidine
Efficiency
21 引用 (Scopus)

Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans

Kobayakawa, K., Kumamaru, H., Saiwai, H., Kubota, K., Ohkawa, Y., Kishimoto, J., Yokota, K., Ideta, R., Shiba, K., Tozaki-Saitoh, H., Inoue, K., Iwamoto, Y. & Okada, S., 10 1 2014, : : Science Translational Medicine. 6, 256, 256ra137.

研究成果: ジャーナルへの寄稿記事

Spinal Cord Injuries
Hyperglycemia
Obese Mice
Nervous System Trauma
Blood Glucose
2 引用 (Scopus)

Acute myocardial infarction following asymptomatic ST elevation despite diltiazem therapy

Egashira, K., Araki, H., Koiwaya, Y., Takeshita, A. & Nakamura, M., 2 1985, : : American heart journal. 109, 2, p. 379-380 2 p.

研究成果: ジャーナルへの寄稿記事

Coronary Vasospasm
Diltiazem
Angina Pectoris
Myocardial Infarction
Therapeutics
16 引用 (Scopus)

Acylated preatroxigenin glycosides from Atroxima congolana

Elbandy, M., Miyamoto, T., Delaude, C. & Lacaille-Dubois, M. A., 9 1 2003, : : Journal of Natural Products. 66, 9, p. 1154-1158 5 p.

研究成果: ジャーナルへの寄稿記事

Saponins
Glycosides
Isomers
glycosides
Spectroscopic analysis
5 引用 (Scopus)

Acylated triterpene saponins from Atroxima liberica STAPF

Tabopda, T. K., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Mirjolet, J. F., Duchamp, O., Ngadjui, B. T. & Lacaille-Dubois, M. A., 11 1 2011, : : Helvetica Chimica Acta. 94, 11, p. 2066-2076 11 p.

研究成果: ジャーナルへの寄稿記事

Triterpenes
Saponins
Isomers
Esters
isomers
37 引用 (Scopus)

Acylated triterpene saponins from the roots of Securidaca longepedunculata

Mitaine-Offer, A. C., Pénez, N., Miyamoto, T., Delaude, C., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., 1 1 2010, : : Phytochemistry. 71, 1, p. 90-94 5 p.

研究成果: ジャーナルへの寄稿記事

Securidaca
Triterpenes
triterpenoid saponins
Saponins
Esters
15 引用 (Scopus)

Acyl-protected hydroxylamines as spin label generators for EPR brain imaging

Yordanov, A. T., Yamada, K. I., Krishna, M. C., Russo, A., Yoo, J., English, S., Mitchell, J. B. & Brechbiel, M. W., 5 23 2002, : : Journal of Medicinal Chemistry. 45, 11, p. 2283-2288 6 p.

研究成果: ジャーナルへの寄稿記事

Hydroxylamines
Spin Labels
Electron Spin Resonance Spectroscopy
Neuroimaging
Hydroxylamine
38 引用 (Scopus)

Addition of bevacizumab enhances antitumor activity of erlotinib against non-small cell lung cancer xenografts depending on VEGF expression

Li, H., Takayama, K., Wang, S., Shiraishi, Y., Gotanda, K., Harada, T., Furuyama, K., Iwama, E., Ieiri, I., Okamoto, I. & Nakanishi, Y., 10 9 2014, : : Cancer chemotherapy and pharmacology. 74, 6, p. 1297-1305 9 p.

研究成果: ジャーナルへの寄稿記事

Heterografts
Non-Small Cell Lung Carcinoma
Vascular Endothelial Growth Factor A
Cells
Tumors

Additions and Corrections: Synthesis and Antibacterial Activity of Thiazolopyrazine-Incorporated Tetracyclic Quinolone Antibacterials (J. Med. Chem. (1994) 37(5) (586–592) (10.1021/jm00031a007))

Inoue, Y., Kondo, H., Taguchi, M., Jinbo, Y., Sakamoto, F. & Tsukamoto, G., 7 1 1994, : : Journal of Medicinal Chemistry. 37, 15, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Quinolones
Nitrogen
Skeleton
43 引用 (Scopus)

Additive effect of N-heteroaromatics on transesterification catalyzed by tetranuclear zinc cluster

Maegawa, Y., Ohshima, T., Hayashi, Y., Agura, K., Iwasaki, T. & Mashima, K., 10 7 2011, : : ACS Catalysis. 1, 10, p. 1178-1182 5 p.

研究成果: ジャーナルへの寄稿記事

Transesterification
Zinc
Catalyst activity
Esters
Alcohols
35 引用 (Scopus)

Additive effects of amines on asymmetric hydrogenation of quinoxalines catalyzed by chiral iridium complexes

Nagano, T., Iimuro, A., Schwenk, R., Ohshima, T., Kita, Y., Togni, A. & Mashima, K., 9 10 2012, : : Chemistry - A European Journal. 18, 37, p. 11578-11592 15 p.

研究成果: ジャーナルへの寄稿記事

Iridium
Quinoxalines
Hydrogenation
Amines
Enantioselectivity

A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats

Shimizu, Y., Yanobu-Takanashi, R., Nakano, K., Hamase, K., Shimizu, T. & Okamura, T., 2 13 2019, : : Mammalian Genome. 30, 1-2, p. 23-33 11 p.

研究成果: ジャーナルへの寄稿記事

Cystine
Kidney
Glucose
Cystinosis
Genes
32 引用 (Scopus)
Base Pairing
Adenosine
DNA
Derivatives
Nucleosides
3 引用 (Scopus)

Adhesive Dimerization of Human P-Cadherin Catalyzed by a Chaperone-like Mechanism

Kudo, S., Caaveiro, J. M. M. & Tsumoto, K., 9 6 2016, : : Structure. 24, 9, p. 1523-1536 14 p.

研究成果: ジャーナルへの寄稿記事

Dimerization
Cadherins
Adhesives
Motion Pictures
Thermodynamics
1 引用 (Scopus)

A dihydrochalcone derivative and further steroidal saponins from Sansevieria trifasciata Prain

Tchegnitegni, B. T., Teponno, R. B., Jenett-Siems, K., Melzig, M. F., Miyamoto, T. & Tapondjou, L. A., 10 26 2017, : : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 72, 11-12, p. 477-482 6 p.

研究成果: ジャーナルへの寄稿記事

Sansevieria
Aconitic Acid
Saponins
Derivatives
Spectroscopic analysis
23 引用 (Scopus)

A disruption mechanism of the molecular clock in a MPTP mouse model of parkinson's disease

Hayashi, A., Matsunaga, N., Okazaki, H., Kakimoto, K., Kimura, Y., Azuma, H., Ikeda, E., Shiba, T., Yamato, M., Yamada, K. I., Koyanagi, S. & Ohdo, S., 6 1 2013, : : NeuroMolecular Medicine. 15, 2, p. 238-251 14 p.

研究成果: ジャーナルへの寄稿記事

AMP-Activated Protein Kinases
Parkinson Disease
Circadian Clocks
Dopaminergic Neurons
Adenosine Triphosphate
8 引用 (Scopus)

Administering xCT inhibitors based on circadian clock improves antitumor effects

Okazaki, F., Naoya, M., Hamamura, K., Suzuki, K., Nakao, T., Okazaki, H., Kutsukake, M., Fukumori, S., Tsuji, Y. & To, H., 12 1 2017, : : Cancer Research. 77, 23, p. 6603-6613 11 p.

研究成果: ジャーナルへの寄稿記事

Sulfasalazine
Circadian Clocks
Circadian Rhythm
Drug Therapy
Cystine
42 引用 (Scopus)

Administration of a decoy against the activator protein-1 binding site suppresses neointimal thickening in rabbit balloon-injured arteries

Kume, M., Komori, K., Matsumoto, T., Onohara, T., Takeuchi, K., Yonemitsu, Y. & Sugimachi, K., 3 12 2002, : : Circulation. 105, 10, p. 1226-1232 7 p.

研究成果: ジャーナルへの寄稿記事

Transcription Factor AP-1
Protein Binding
Arteries
Binding Sites
Rabbits
100 引用 (Scopus)

A dominant negative form of the AAA ATPase SKD1/VPS4 impairs membrane trafficking out of endosomal/lysosomal compartments: Class E vps phenotype in mammalian cells

Fujita, H., Yamanaka, M., Imamura, K., Tanaka, Y., Nara, A., Yoshimori, T., Yokota, S. & Himeno, M., 1 15 2003, : : Journal of Cell Science. 116, 2, p. 401-414 14 p.

研究成果: ジャーナルへの寄稿評論記事

Endosomes
Lysosomes
Adenosine Triphosphatases
Phenotype
Membranes
4 引用 (Scopus)

ADP-ribosyl cyclase as a therapeutic target for central nervous system diseases

Salmina, A. B., Olovyannikova, R. Y., Noda, M. & Higashida, H., 10 6 2006, : : Central Nervous System Agents in Medicinal Chemistry. 6, 3, p. 193-210 18 p.

研究成果: ジャーナルへの寄稿評論記事

ADP-ribosyl Cyclase
Cyclic ADP-Ribose
Central Nervous System Diseases
NAD
Neurons

Adrenergic receptor signaling and regulation

Kurose, H., 12 1 2003, : : Folia Pharmacologica Japonica. 122, SUPPL. 1

研究成果: ジャーナルへの寄稿記事

Arrestin
G-Protein-Coupled Receptors
Adrenergic Receptors
Signal Transduction
Proteins
201 引用 (Scopus)

Adrenergic regulation of clock gene expression in mouse liver

Terazono, H., Mutoh, T., Yamaguchi, S., Kobayashi, M., Akiyama, M., Udo, R., Ohdo, S., Okamura, H. & Shibata, S., 5 27 2003, : : Proceedings of the National Academy of Sciences of the United States of America. 100, 11, p. 6795-6800 6 p.

研究成果: ジャーナルへの寄稿記事

Gene Expression Regulation
Adrenergic Agents
Suprachiasmatic Nucleus
Epinephrine
Liver
26 引用 (Scopus)

Advanced method for high-throughput expression of mutated eukaryotic membrane proteins in Saccharomyces cerevisiae

Ito, K., Sugawara, T., Shiroishi, M., Tokuda, N., Kurokawa, A., Misaka, T., Makyio, H., Yurugi-Kobayashi, T., Shimamura, T., Nomura, N., Murata, T., Abe, K., Iwata, S. & Kobayashi, T., 7 11 2008, : : Biochemical and Biophysical Research Communications. 371, 4, p. 841-845 5 p.

研究成果: ジャーナルへの寄稿記事

Yeast
Saccharomyces cerevisiae
Membrane Proteins
Yeasts
Homologous Recombination
32 引用 (Scopus)

Advantageous application of a surface coil to EPR irradiation in overhauser-enhanced MRI

Matsumoto, S., Yamada, K-I., Hirata, H., Yasukawa, K., Hyodo, F., Ichikawa, K. & Utsumi, H., 4 1 2007, : : Magnetic Resonance in Medicine. 57, 4, p. 806-811 6 p.

研究成果: ジャーナルへの寄稿記事

Electron Spin Resonance Spectroscopy
Free Radicals
Protons
350 引用 (Scopus)

Adverse outcomes of interrupted precordial compression during automated defibrillation

Nakamura, R., Egashira, K., Machida, Y., Hayashidani, S., Takeya, M., Utsumi, H., Tsutsui, H. & Takeshita, A., 7 16 2002, : : Circulation. 106, 3, p. 368-372 5 p.

研究成果: ジャーナルへの寄稿記事

Shock
Defibrillators
Cardiopulmonary Resuscitation
Thorax
Ventricular Fibrillation
1 引用 (Scopus)

A Facile Synthesis of Benzoshikonin and Benzocycloshikonin

Aso, M., Hayakawa, K. & Kanematsu, K., 1 1 1988, : : Tetrahedron Letters. 29, 1, p. 85-88 4 p.

研究成果: ジャーナルへの寄稿記事

Cyclic Ethers
shikonin
34 引用 (Scopus)

Affinity improvement of a therapeutic antibody by structure-based computational design: generation of electrostatic interactions in the transition state stabilizes the antibody-antigen complex

Kiyoshi, M., Caaveiro, J. M. M., Miura, E., Nagatoishi, S., Nakakido, M., Soga, S., Shirai, H., Kawabata, S. & Tsumoto, K., 2014, : : PLoS One. 9, 1, 9 p., e87099.

研究成果: ジャーナルへの寄稿記事

公開
antigen-antibody complex
electrostatic interactions
Coulomb interactions
Antigen-Antibody Complex
Static Electricity
22 引用 (Scopus)
Cathepsin H
Epithelial Attachment
Cathepsin B
Cysteine Proteases
Horseradish Peroxidase