研究成果 1976 2020

Bif-1/Endophilin B1/SH3GLB1 regulates bone homeostasis

Touyama, K., Khan, M., Aoki, K., Matsuda, M., Hiura, F., Takakura, N., Matsubara, T., Harada, Y., Hirohashi, Y., Tamura, Y., Gao, J., Mori, K., Kokabu, S., Yasuda, H., Fujita, Y., Watanabe, K., Takahashi, Y., Maki, K. & Jimi, E., 11 1 2019, : : Journal of Cellular Biochemistry. 120, 11, p. 18793-18804 12 p.

研究成果: ジャーナルへの寄稿記事

Bone
Homeostasis
Bone and Bones
Osteoclasts
Osteogenesis
14 引用 (Scopus)

Bile acid-regulated peroxisome proliferator-activated receptor-α (PPARα) activity underlies circadian expression of intestinal peptide absorption transporter PepT1/Slc15a1

Okamura, A., Koyanagi, S., Dilxiat, A., Kusunose, N., Chen, J. J., Matsunaga, N., Shibata, S. & Ohdo, S., 1 1 2014, : : Journal of Biological Chemistry. 289, 36, p. 25296-25305 10 p.

研究成果: ジャーナルへの寄稿記事

Peroxisome Proliferator-Activated Receptors
Intestinal Absorption
Bile Acids and Salts
Peptides
Transcriptional Activation
21 引用 (Scopus)

Binding of HTm4 to cyclin-dependent kinase (Cdk)-associated phosphatase (KAP)·Cdk2·cyclin A complex enhances the phosphatase activity of KAP, dissociates cyclin A, and facilitates KAP dephosphorylation of Cdk2

Chinami, M., Yano, Y., Yang, X., Salahuddin, S., Moriyama, K., Shiroishi, M., Turner, H., Shirakawa, T. & Adra, C. N., 4 29 2005, : : Journal of Biological Chemistry. 280, 17, p. 17235-17242 8 p.

研究成果: ジャーナルへの寄稿記事

Cyclin A
Cyclin-Dependent Kinases
Phosphoric Monoester Hydrolases
Cyclin-Dependent Kinase 2
Phosphorylation

Binding of two bis-bipyridine minor groove binders to a DNA template in the presence of Cu2+ ions.

Brazier, J. A., Onishi, I. & Sasaki, S., 12 1 2008, : : Nucleic acids symposium series (2004). 52, p. 107-108 2 p.

研究成果: ジャーナルへの寄稿記事

Ions
Ligands
DNA
Trinucleotide Repeats
Spectrum Analysis
18 引用 (Scopus)

Bioactive diterpenoids from octocorallia, 2. deoxyxeniolide B, a novel ichthyotoxic diterpenoid from the soft coral xenia elongata

Miyamoto, T., Takenaka, Y., Yamada, K. & Higuchi, R., 6 1995, : : Journal of Natural Products. 58, 6, p. 924-928 5 p.

研究成果: ジャーナルへの寄稿記事

Anthozoa
Diterpenes
Spectrum analysis
Oxidation
deoxyxeniolide B
14 引用 (Scopus)

Bioactive steroidal saponins from Smilax medica

Sautour, M., Miyamoto, T. & Lacaille-Dubois, M. A., 6 1 2006, : : Planta medica. 72, 7, p. 667-670 4 p.

研究成果: ジャーナルへの寄稿記事

Smilax
Spirostans
steroid saponins
Candida glabrata
Candida tropicalis
48 引用 (Scopus)

Bioactive terpenoids from Octocorallia, I. Bioactive diterpenoids: Litophynols A and B from the mucus of the soft coral Litophyton sp.

Miyamoto, T., Yamada, K., Ikeda, N., Komori, T. & Higuchi, R., 9 1 1994, : : Journal of Natural Products. 57, 9, p. 1212-1219 8 p.

研究成果: ジャーナルへの寄稿記事

Anthozoa
Diterpenes
Terpenes
Mucus
X-Rays
49 引用 (Scopus)

Bioactive terpenoids from octocorallia. 3. A new eunicellin-based diterpenoid from the soft coral Cladiella sphaeroides

Yamada, K., Ogata, N., Ryu, K., Miyamoto, T., Komori, T. & Higuchi, R., 1 1 1997, : : Journal of Natural Products. 60, 4, p. 393-396 4 p.

研究成果: ジャーナルへの寄稿記事

Anthozoa
Diterpenes
Terpenes
diterpenoids
terpenoids
37 引用 (Scopus)

Bioactive terpenoids from octocorallia. 4. Three new cembrane-type diterpenoids from the soft coral Lobophytum schoedei

Yamada, K., Ryu, K., Miyamoto, T. & Higuchi, R., 1 1 1997, : : Journal of Natural Products. 60, 8, p. 798-801 4 p.

研究成果: ジャーナルへの寄稿記事

Gambusia
Cyprinodontiformes
Oryzias
Artemia
Oryzias latipes
8 引用 (Scopus)

Bioactivity of American ginseng by knockout extract preparation using monoclonal antibody

Yuan, C. S. & Tanaka, H., 3 1 2011, : : Current Drug Discovery Technologies. 8, 1, p. 32-41 10 p.

研究成果: ジャーナルへの寄稿記事

Panax
Fruit
Monoclonal Antibodies
Blood Glucose
Fasting
37 引用 (Scopus)

Biochemical analysis of the movement of a major lysosomal membrane glycoprotein in the endocytic membrane system

Furuno, K., Yano, S., Akasaki, K., Tanaka, Y., Yamaguchi, Y., Tsuji, H., Himeno, M. & Kato, K., 1 1 1989, : : Journal of biochemistry. 106, 4, p. 717-722 6 p.

研究成果: ジャーナルへの寄稿記事

Lysosome-Associated Membrane Glycoproteins
Membranes
Immunoglobulin G
Lysosomes
Antibodies
4 引用 (Scopus)

Biochemical characterization of liver microsomal, golgi, lysosomal, and serum β-glucuronidases in dibuty1 phosphate-treated rats

Nishimura, Y., Kato, K. & Himeno, M., 1 1 1995, : : Journal of biochemistry. 118, 1, p. 56-66 11 p.

研究成果: ジャーナルへの寄稿記事

Glucuronidase
Liver
Rats
Phosphates
Serum
6 引用 (Scopus)

Biochemical Properties and Intracellular Processing of Lysosomal Cathepsins B and H

Nishimura, Y., Tsuji, H., Kato, K., Sato, H., Amano, J., Himeno, M. & Tsuji, H., 1 1 1995, : : Biological and Pharmaceutical Bulletin. 18, 6, p. 829-836 8 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Cathepsin B
Radioactivity
yeast proteinase B
Lysosomes
7 引用 (Scopus)

Bioconjugation of Oligodeoxynucleotides Carrying 1,4-Dicarbonyl Groups via Reductive Amination with Lysine Residues

Yang, B., Jinnouchi, A., Usui, K., Katayama, T., Fujii, M., Suemune, H. & Aso, M., 8 19 2015, : : Bioconjugate Chemistry. 26, 8, p. 1830-1838 9 p.

研究成果: ジャーナルへの寄稿記事

Amination
Oligodeoxyribonucleotides
Lysine
Aldehydes
Amines
1 引用 (Scopus)

Bioconjugation with Thiols by Benzylic Substitution

Watanabe, K. & Ohshima, T., 3 15 2018, : : Chemistry - A European Journal. 24, 16, p. 3959-3964 6 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Sulfhydryl Compounds
Substitution reactions
Enzymes
Kinetics
Kampo Medicine
Body Composition
Electric Impedance
Edema
Muscles

Biogenesis and maintenance of endosome/lysosome

Himeno, M., Fujita, H. & Tanaka, Y., 1 1 2003, : : Seikagaku. The Journal of Japanese Biochemical Society. 75, 6, p. 486-491 6 p.

研究成果: ジャーナルへの寄稿評論記事

Lysosome-Associated Membrane Glycoproteins
CD36 Antigens
Repressor Proteins
Intracellular Membranes
Endosomes
3 引用 (Scopus)

BioKnife, a modified sendai virus, to resect malignant tumors

Yonemitsu, Y., Ueda, Y. & Hasegawa, M., 9 1 2013, Sendai Virus Vector: Advantages and Applications. Springer Japan, p. 151-169 19 p.

研究成果: 著書/レポートタイプへの貢献

Sendai virus
Urokinase-Type Plasminogen Activator
Neoplasms
Metalloproteases
Peptide Hydrolases
16 引用 (Scopus)

BioKnife, a uPA activity-dependent oncolytic sendai virus, eliminates pleural spread of malignant mesothelioma via simultaneous stimulation of uPA expression

Morodomi, Y., Yano, T., Kinoh, H., Harada, Y., Saito, S., Kyuragi, R., Yoshida, K., Onimaru, M., Shoji, F., Yoshida, T., Ito, K., Shikada, Y., Maruyama, R., Hasegawa, M., Maehara, Y. & Yonemitsu, Y., 4 2012, : : Molecular Therapy. 20, 4, p. 769-777 9 p.

研究成果: ジャーナルへの寄稿記事

Oncolytic Viruses
Sendai virus
Urokinase Plasminogen Activator Receptors
NFI Transcription Factors
Pleural Cavity
3 引用 (Scopus)

Biological clock and chronopharmacology

Ohdo, S., 6 1 2007, : : Japanese Journal of Neuropsychopharmacology. 27, 3, p. 95-102 8 p.

研究成果: ジャーナルへの寄稿評論記事

Biological Clocks
Pharmaceutical Preparations
Physiological Phenomena
Circadian Clocks
Suprachiasmatic Nucleus
29 引用 (Scopus)

Biologically active gangliosides from echinoderms

Higuchi, R., Inagaki, M., Yamada, K. & Miyamoto, T., 10 1 2007, : : Journal of Natural Medicines. 61, 4, p. 367-370 4 p.

研究成果: ジャーナルへの寄稿評論記事

Gangliosides
Stars
Cucumaria
Holothuria
Stichopus
28 引用 (Scopus)

Biologically active glycosides from asteroida, XXXIV: Isolation and structure of cerebrosides from the starfish Stellaster equestris

Higuchi, R., Harano, Y., Mitsuyuki, M., Isobe, R., Yamada, K., Miyamoto, T. & Komori, T., 4 1 1996, : : Liebigs Annales. 4, p. 593-599 7 p.

研究成果: ジャーナルへの寄稿記事

Cerebrosides
Glycosides
Chloroform
Methanol
10 引用 (Scopus)

Biologically active glycosides from asteroidea, 35: Isolation and structure of four new steroid glycoside di-O-sulfates from the starfish Asteropecten latespinosus

Higuchi, R., Fujita, M., Matsumoto, S., Yamada, K., Miyamoto, T. & Sasaki, T., 5 1 1996, : : Liebigs Annales. 5, p. 837-840 4 p.

研究成果: ジャーナルへの寄稿記事

Trientine
Glycosides
Chloroform
Sulfates
Methanol
23 引用 (Scopus)

Biologically active glycosides from asteroidea, 36: Re-examination of the structure of acanthaganglioside C, and the identification of three minor acanthagangliosides F, G and H

Miyamoto, T., Inagaki, M., Isobe, R., Tanaka, Y., Higuchi, R., Iha, M. & Teruya, K., 5 1997, : : Liebigs Annales. 5, p. 931-936 6 p.

研究成果: ジャーナルへの寄稿記事

Neuraminic Acids
Gangliosides
Glycosides
Galactose
Experiments
16 引用 (Scopus)

Biologically active glycosides from asteroidea, 37. Glycosphingolipids from the starfish Luidia maculata, 1: Structure of a new sulfatide molecular species

Kawatake, S., Inagaki, M., Isobe, R., Miyamoto, T. & Higuchi, R., 1 1 1997, : : Liebigs Annales. 8, p. 1797-1800 4 p.

研究成果: ジャーナルへの寄稿記事

Sulfoglycosphingolipids
Glycosphingolipids
Glycosides
Molecular mass
Chloroform
25 引用 (Scopus)
G(M3) Ganglioside
Glycosphingolipids
glucosides
Gangliosides
Glycosides
25 引用 (Scopus)

Biologically active glycosides from asteroidea, 40 two new gangliosides, acanthagangliosides I and J from the starfish Acanthaster planci

Miyamoto, T., Yamamoto, A., Wakabayashi, M., Nagaregawa, Y., Inagaki, M., Higuchi, R., Iha, M. & Teruya, K., 6 1 2000, : : European Journal of Organic Chemistry. 12, p. 2295-2301 7 p.

研究成果: ジャーナルへの寄稿記事

glucosides
Gangliosides
Glycosides
hydrolysis
Enzymatic hydrolysis
25 引用 (Scopus)

Biologically active glycosides from asteroidea, 42. Isolation and structure of a new biologically active ganglioside molecular species from the starfish Asterina pectinifera

Higuchi, R., Inoue, S., Inagaki, K., Sakai, M., Miyamoto, T., Komori, T., Inagaki, M. & Isobe, R., 3 1 2006, : : Chemical and Pharmaceutical Bulletin. 54, 3, p. 287-291 5 p.

研究成果: ジャーナルへの寄稿記事

Asterina
Starfish
Gangliosides
Glycosides
endoglycoceramidase
21 引用 (Scopus)
Starfish
Gangliosides
Glycosides
Molecular mass
Pheochromocytoma
10 引用 (Scopus)

Biologically active quinolone alkaloids from Evodia rutaecarpa on Artemia salina

Kim, Y. C., Kim, N. Y., Jeong, S. J., Sohn, D. H., Miyamoto, T. & Higuchi, R., 7 13 1998, : : Planta Medica. 64, 5, 1 p.

研究成果: ジャーナルへの寄稿記事

Evodia
Quinolones
Alkaloids
Salinum
16 引用 (Scopus)
Bearings (structural)
Crown Ethers
Biomimetics
Sulfhydryl Compounds
Esters
1 引用 (Scopus)

Biophysical analysis of the protein-small molecule interactions to develop small molecule drug discovery

Nagatoishi, S., Caaveiro, J. M. M. & Tsumoto, K., 1 1 2018, : : Yakugaku Zasshi. 138, 8, p. 1033-1041 9 p.

研究成果: ジャーナルへの寄稿評論記事

Drug Discovery
Small Molecule Libraries
Thermodynamics
Proteins
Research Personnel
23 引用 (Scopus)

Biophysical characterization of O-glycosylated CD99 recognition by paired Ig-like type 2 receptors

Tabata, S., Kuroki, K., Wang, J., Kajikawa, M., Shiratori, I., Kohda, D., Arase, H. & Maenaka, K., 4 4 2008, : : Journal of Biological Chemistry. 283, 14, p. 8893-8901 9 p.

研究成果: ジャーナルへの寄稿記事

Surface Plasmon Resonance
Surface plasmon resonance
Mutagenesis
Thermodynamics
Leukocyte Rolling
2 引用 (Scopus)

Biosynthesis, processing, and lysosome targeting of acid phosphatase

Himeno, M. & Tanaka, Y., 1 1 1995, : : Nippon rinsho. Japanese journal of clinical medicine. 53, 12, p. 2898-2903 6 p.

研究成果: ジャーナルへの寄稿評論記事

Acid Phosphatase
Lysosomes
Membranes
Liver
Enzymes
8 引用 (Scopus)

Biosynthesis and Processing of Lysosomal Cathepsin D in Primary Cultures of Rat Hepatocytes

Nishimura, Y., Kato, K., Himeno, M. & Koji, F., 1 1 1995, : : Biological and Pharmaceutical Bulletin. 18, 6, p. 825-828 4 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
Enzyme Precursors
Hepatocytes
Tunicamycin
Chloroquine
55 引用 (Scopus)

Biosynthesis and processing of lysosomal cathepsin L in primary cultures of rat hepatocytes

Nishimura, Y., Furuno, K. & Kato, K., 5 15 1988, : : Archives of Biochemistry and Biophysics. 263, 1, p. 107-116 10 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
Biosynthesis
Enzyme Precursors
Rats
Hepatocytes
22 引用 (Scopus)

Biosynthesis of drimane terpenoids in dorid molluscs: Pivotal role of 7- deacetoxyolepupuane in two species of Dendrodoris nudibranchs

Fontana, A., Ciavatta, M. L., Miyamoto, T., Spinella, A. & Cimino, G., 4 30 1999, : : Tetrahedron. 55, 18, p. 5937-5946 10 p.

研究成果: ジャーナルへの寄稿記事

Molluscs
Mollusca
Biosynthesis
Terpenes
Nuclear magnetic resonance spectroscopy
45 引用 (Scopus)

Biosynthesis of lysosomal cathepsins B and H in cultured rat hepatocytes

Nishimura, Y., Amano, J., Sato, H., Tsuji, H. & Kato, K., 4 1988, : : Archives of Biochemistry and Biophysics. 262, 1, p. 159-170 12 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Cathepsin B
Enzyme Precursors
Biosynthesis
Rats
22 引用 (Scopus)

Biosythesis processing, and intracellular transport of lysosomal acid phosphatase in rat hepatocytes

Tanaka, Y., Harada, R., Himeno, M. & Kato, K., 1 1 1990, : : Journal of biochemistry. 108, 2, p. 278-286 9 p.

研究成果: ジャーナルへの寄稿記事

Acid Phosphatase
Rats
Hepatocytes
Lysosomes
Processing
5 引用 (Scopus)

Bipyrrole derivatives as new DNA-minor groove binders

Tanada, M., Shibata, Y., Maeda, M. & Sasaki, S., 1 1 2004, : : Heterocycles. 63, 1, p. 29-39 11 p.

研究成果: ジャーナルへの寄稿記事

Binders
Derivatives
DNA
Bisbenzimidazole
Nucleotide Motifs
41 引用 (Scopus)

Bisindolylmaleimides with large stokes shift and long-lasting chemiluminescence properties

Nakazono, M., Nanbu, S., Uesaki, A., Kuwano, R., Kashiwabara, M. & Zaitsu, K., 8 30 2007, : : Organic Letters. 9, 18, p. 3583-3586 4 p.

研究成果: ジャーナルへの寄稿記事

Chemiluminescence
chemiluminescence
Luminescence
Fluorescence
Wavelength
129 引用 (Scopus)

Blockade of a chemokine, CCL2, reduces chronic colitis-associated carcinogenesis in mice

Popivanova, B. K., Kostadinova, F. I., Furuichi, K., Shamekh, M. M., Kondo, T., Wada, T., Egashira, K. & Mukaida, N., 10 1 2009, : : Cancer Research. 69, 19, p. 7884-7892 9 p.

研究成果: ジャーナルへの寄稿記事

Chemokine CCL2
Colitis
Colon
Carcinogenesis
Cyclooxygenase 2
34 引用 (Scopus)

Blockade of monocyte chemoattractant protein-1 by adenoviral gene transfer inhibits experimental vein graft neointimal formation

Tatewaki, H., Egashira, K., Kimura, S., Nishida, T., Morita, S. & Tominaga, R., 6 1 2007, : : Journal of Vascular Surgery. 45, 6, p. 1236-1243 8 p.

研究成果: ジャーナルへの寄稿記事

Chemokine CCL2
Veins
Transplants
Genes
Lac Operon
111 引用 (Scopus)

Blockade of vascular endothelial growth factor suppresses experimental restenosis after intraluminal injury by inhibiting recruitment of monocyte lineage cells

Ohtani, K., Egashira, K., Hiasa, K. I., Zhao, Q., Kitamoto, S., Ishibashi, M., Usui, M., Inoue, S., Yonemitsu, Y., Sueishi, K., Sata, M., Shibuya, M. & Sunagawa, K., 10 19 2004, : : Circulation. 110, 16, p. 2444-2452 9 p.

研究成果: ジャーナルへの寄稿記事

Vascular Endothelial Growth Factor A
Monocytes
Wounds and Injuries
Genes
Vascular Endothelial Growth Factor Receptor-1
70 引用 (Scopus)

Blockade of VEGF accelerates proteinuria, via decrease in nephrin expression in rat crescentic glomerulonephritis

Hara, A., Wada, T., Furuichi, K., Sakai, N., Kawachi, H., Shimizu, F., Shibuya, M., Matsushima, K., Yokoyama, H., Egashira, K. & Kaneko, S., 6 2006, : : Kidney International. 69, 11, p. 1986-1995 10 p.

研究成果: ジャーナルへの寄稿記事

Glomerulonephritis
Vascular Endothelial Growth Factor Receptor-1
Proteinuria
Vascular Endothelial Growth Factor A
Kidney
7 引用 (Scopus)

Blocker-resistant presynaptic voltage-dependent Ca 2+ channels underlying glutamate release in mice nucleus tractus solitarii

Yamazaki, K., Shigetomi, E., Ikeda, R., Nishida, M., Kiyonaka, S., Mori, Y. & Kato, F., 8 9 2006, : : Brain Research. 1104, 1, p. 103-113 11 p.

研究成果: ジャーナルへの寄稿記事

Solitary Nucleus
Synapses
Glutamic Acid
Agatoxins
Conotoxins
33 引用 (Scopus)

Blocking of monocyte chemoattractant protein-1 (MCP-1) activity attenuates the severity of acute pancreatitis in rats

Ishibashi, T., Zhao, H., Kawabe, K., Oono, T., Egashira, K., Suzuki, K., Nawata, H., Takayanagi, R. & Ito, T., 1 1 2008, : : Journal of gastroenterology. 43, 1, p. 79-85 7 p.

研究成果: ジャーナルへの寄稿記事

Chemokine CCL2
Pancreatitis
Genes
Amylases
Pancreas
19 引用 (Scopus)

Bone marrow-derived cells in the population of spinal microglia after peripheral nerve injury

Tashima, R., Mikuriya, S., Tomiyama, D., Shiratori-Hayashi, M., Yamashita, T., Kohro, Y., Tozaki-Saitoh, H., Inoue, K. & Tsuda, M., 3 23 2016, : : Scientific reports. 6, 23701.

研究成果: ジャーナルへの寄稿記事

Peripheral Nerve Injuries
Microglia
Bone Marrow Cells
Population
Spinal Cord
117 引用 (Scopus)

Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice.

Ishibashi, M., Egashira, K., Zhao, Q., Hiasa, K. I., Ohtani, K., Ihara, Y., Charo, I. F., Kura, S., Tsuzuki, T., Takeshita, A. & Sunagawa, K., 11 2004, : : Arteriosclerosis, thrombosis, and vascular biology. 24, 11, p. e174-178

研究成果: ジャーナルへの寄稿記事

CCR2 Receptors
Apolipoproteins E
Angiotensin II
Aneurysm
Atherosclerosis
53 引用 (Scopus)

Bone marrow mononuclear cell therapy limits myocardial infarct size through vascular endothelial growth factor

Hiasa, K. I., Egashira, K., Kitamoto, S., Ishibashi, M., Inoue, S., Ni, W., Zhao, Q., Nagata, S., Katoh, M., Sata, M. & Takeshita, A., 5 1 2004, : : Basic Research in Cardiology. 99, 3, p. 165-172 8 p.

研究成果: ジャーナルへの寄稿記事

Cell- and Tissue-Based Therapy
Bone Marrow Cells
Vascular Endothelial Growth Factor A
Myocardial Infarction
Infarction