研究成果 1976 2020

螺旋空間を利用した新規不斉リン配位子の開発と不斉触媒反応への応用

Usui, K., 11 1 2017, : : Yakugaku Zasshi. 137, 11, p. 1381-1390 10 p.

研究成果: ジャーナルへの寄稿記事

phosphine
Ligands
Indoles
Synthetic Chemistry Techniques
Acetates

複数回膜貫通型膜タンパク質の立体構造形成機構: バンド3タンパク質研究の成果より

阿部義人 & 濱崎直孝, 1 25 2006, : : Biophysics (Japan). 46, 1, p. 4-9 6 p.

研究成果: ジャーナルへの寄稿記事

Erythrocyte Anion Exchange Protein 1
Protein Sorting Signals
Membrane Proteins
Membranes
Lipids

新しい概念に基づく不斉触媒の創製と医薬関連物質合成への展開

柴崎正勝, 金井求, 大嶋孝志 & 松永茂樹, 2004, 柴崎正勝/金井求.

研究成果: 著書/レポートタイプ著書

化学を学ぶ人のレポート・論文・発表マスターガイド

今田泰嗣, 大嶋孝志 & 廣瀬敬治, 2010, 化学同人.

研究成果: 著書/レポートタイプ著書

黄色ブドウ球菌の鉄取り込み機構:ISD

Martinez Caaveiro, J. M. & Tsumoto, K., 1 1 2018, : : Seikagaku. 90, 3, p. 279-289 11 p.

研究成果: ジャーナルへの寄稿記事

Heme
Staphylococcus aureus
Iron

μSr study of 1:1 complex of bis(hexafluoroacetylacetonate) manganese(II) with diazodi(4-pyridyl)methan as a photo-responsible magnetic coupler

Ajiro, Y., Asano, T., Inagaki, Y., Karasawa, S., Koga, N., Nishiyama, K., Miyake, Y. & Nagamine, K., 1 1 2000, : : Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals. 343, p. 421/103 - 426/108

研究成果: ジャーナルへの寄稿Conference article

Manganese
couplers
manganese
Irradiation
irradiation
11 引用 (Scopus)
Amino alcohols
Amino Alcohols
Acylation
Transesterification
Alcohols
23 引用 (Scopus)

Δ9-tetrahydrocannabinol elicited ipsilateral circling behavior in rats with unilateral nigral lesion

Sakurai, Y., Ohta, H., Shimazoe, T., Kataoka, Y., Fujiwara, M. & Ueki, S., 12 9 1985, : : Life Sciences. 37, 23, p. 2181-2185 5 p.

研究成果: ジャーナルへの寄稿記事

Dronabinol
Substantia Nigra
Rats
Oxidopamine
Dopaminergic Neurons

Δ 9 -Tetrahydrocannabinol elicited 22-kHz ultrasonic vocalization changes after air puff stimulus through CB 1 receptor in adult rats

Myose, T., Shirakawa, A., Irie, K., Yamashita, Y., Nakano, T., Takase, Y., Matsuo, K., Satho, T., Tuchihashi, R., Kinjo, J., Tanaka, H., Morimoto, S., Funada, M., Sano, K. & Mishima, K., 5 14 2019, : : Neuroscience Letters. 701, p. 132-135 4 p.

研究成果: ジャーナルへの寄稿記事

Dronabinol
Ultrasonics
Air
rimonabant
Cannabinoid Receptors
16 引用 (Scopus)

βγ subunits of Gi/o suppress EGF-induced ERK5 phosphorylation, whereas ERK1/2 phosphorylation is enhanced

Obara, Y., Okano, Y., Ono, S., Yamauchi, A., Hoshino, T., Kurose, H. & Nakahata, N., 7 1 2008, : : Cellular Signalling. 20, 7, p. 1275-1283 9 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor
Phosphorylation
PC12 Cells
G-Protein-Coupled Receptors
Lysophosphatidic Acid Receptors
19 引用 (Scopus)

β-arrestin-mediated signaling improves the efficacy of therapeutics

Ibrahim, I. A. A. E. H. & Kurose, H., 10 12 2012, : : Journal of Pharmacological Sciences. 118, 4, p. 408-412 5 p.

研究成果: ジャーナルへの寄稿評論記事

Arrestin
GTP-Binding Proteins
Arrestins
Therapeutics
G-Protein-Coupled Receptors
29 引用 (Scopus)

β-arrestin2 in Infiltrated Macrophages Inhibits Excessive Inflammation after Myocardial Infarction

Watari, K., Michio, N., Nishida, M., Kim, K. M. & Kurose, H., 7 8 2013, : : PloS one. 8, 7, e68351.

研究成果: ジャーナルへの寄稿記事

Macrophages
myocardial infarction
Knockout Mice
macrophages
inflammation
32 引用 (Scopus)

β-Arrestin2 enhances β2-adrenergic receptor-mediated nuclear translocation of ERK

Kobayashi, H., Narita, Y., Nishida, M. & Kurose, H., 10 1 2005, : : Cellular Signalling. 17, 10, p. 1248-1253 6 p.

研究成果: ジャーナルへの寄稿記事

Extracellular Signal-Regulated MAP Kinases
Adrenergic Receptors
Arrestin
COS Cells
Pertussis Toxin
12 引用 (Scopus)

β-Adrenergic receptor and insulin resistance in the heart

Mangmool, S., Denkaew, T., Parichatikanond, W. & Kurose, H., 1 2017, : : Biomolecules and Therapeutics. 25, 1, p. 44-56 13 p.

研究成果: ジャーナルへの寄稿記事

Adrenergic Receptors
Insulin Resistance
Insulin
Heart Failure
Sympathetic Nervous System
15 引用 (Scopus)

β2-adrenoceptor agonists induce the mammalian clock gene, hPer1, mRNA in cultured human bronchial epithelium cells in vitro

Takata, M., Burioka, N., Ohdo, S., Fukuoka, Y., Miyata, M., Endo, M., Suyama, H. & Shimizu, E., 10 4 2005, : : Chronobiology International. 22, 4, p. 777-783 7 p.

研究成果: ジャーナルへの寄稿記事

Procaterol
Adrenergic Receptors
Fenoterol
Epithelium
Messenger RNA
6 引用 (Scopus)

β2adrenergic receptors: Structure, regulation and signaling by partial and full agonists

Kurose, H., 12 2004, : : Allergology International. 53, 4, p. 321-330 10 p.

研究成果: ジャーナルへの寄稿評論記事

Arrestin
G-Protein-Coupled Receptor Kinases
Adrenergic Receptors
Second Messenger Systems
G-Protein-Coupled Receptors
7 引用 (Scopus)

α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs

Kumazaki, M., Ando, H., Kakei, M., Ushijima, K., Taniguchi, Y., Yoshida, M., Yamato, S., Washino, S., Koshimizu, T. A. & Fujimura, A., 4 5 2013, : : European Journal of Pharmacology. 705, 1-3, p. 1-10 10 p.

研究成果: ジャーナルへの寄稿記事

Thioctic Acid
Guinea Pigs
Dimercaprol
Acute Promyelocytic Leukemia
Therapeutics
4 引用 (Scopus)

α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis

Takeda, T., Matsuo, Y., Nishida, K., Fujiki, A., Hattori, Y., Koga, T., Ishii, Y. & Yamada, H., 1 1 2017, : : Journal of Toxicological Sciences. 42, 1, p. 13-23 11 p.

研究成果: ジャーナルへの寄稿記事

Thioctic Acid
AMP-Activated Protein Kinases
Dioxins
Citric Acid Cycle
Brain
41 引用 (Scopus)

α1-adrenoceptor-Gq-RhoA signaling is upregulated to increase myofibrillar Ca2+ sensitivity in failing hearts

Suematsu, N., Satoh, S., Kinugawa, S., Tsutsui, H., Hayashidani, S., Nakamura, R., Egashira, K., Makino, N. & Takeshita, A., 8 29 2001, : : American Journal of Physiology - Heart and Circulatory Physiology. 281, 2 50-2, p. H637-H646

研究成果: ジャーナルへの寄稿記事

Phenylephrine
Gq-G11 GTP-Binding Protein alpha Subunits
Adrenergic Receptors
rho-Associated Kinases
Myocardium

リゾチームの触媒機構:無脊椎動物型とニワトリ型の比較から

阿部義人, 2017, : : 生物物理. 57, 3, p. 140-143 4 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Acetylglucosamine
Oligomers
Invertebrates
Hydrolysis

ミトコンドリア膜透過装置rat Tom20p cytoplasmic domainの溶液構造

阿部義人, 小代俊浩, 遠藤斗志也 & 神田大輔, 9 7 1998, : : Biophysics (Japan). 38, 2, p. S5

研究成果: ジャーナルへの寄稿記事

アサリ貝リゾチームの構造と機能

阿部義人 & 植田正, 4 25 2009, : : Seikagaku. The Journal of Japanese Biochemical Society. 81, 4, p. 314-319 6 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Y-box binding protein YBX1 and its correlated genes as biomarkers for poor outcomes in patients with breast cancer

Shibata, T., Tokunaga, E., Hattori, S., Watari, K., Murakami, Y., Yamashita, N., Oki, E., Itou, J., Toi, M., Maehara, Y., Kuwano, M. & Ono, M., 12 1 2018, : : Oncotarget. 9, 98, p. 37216-37228 13 p.

研究成果: ジャーナルへの寄稿記事

Carrier Proteins
Biomarkers
Breast Neoplasms
Genes
Databases
23 引用 (Scopus)

Y-box binding protein-1 contributes to both HER2/ErbB2 expression and lapatinib sensitivity in human gastric cancer cells

Shibata, T., Kan, H., Murakami, Y., Ureshino, H., Watari, K., Kawahara, A., Kage, M., Hattori, S., Ono, M. & Kuwano, M., 5 1 2013, : : Molecular Cancer Therapeutics. 12, 5, p. 737-746 10 p.

研究成果: ジャーナルへの寄稿記事

Y-Box-Binding Protein 1
Stomach Neoplasms
Epidermal Growth Factor Receptor
Phosphotransferases
erbB-2 Genes
52 引用 (Scopus)

Y-box binding protein-1 (YB-1) promotes cell cycle progression through CDC6-dependent pathway in human cancer cells

Basaki, Y., Taguchi, K. I., Izumi, H., Murakami, Y., Kubo, T., Hosoi, F., Watari, K., nakano, K., Kawaguchi, H., Ohno, S., Kohno, K., Ono, M. & Kuwano, M., 3 1 2010, : : European Journal of Cancer. 46, 5, p. 954-965 12 p.

研究成果: ジャーナルへの寄稿記事

Y-Box-Binding Protein 1
Cell Cycle
Cell Proliferation
Neoplasms
S Phase

X-ray crystal structure of Escherichia coli HspQ, a protein involved in the retardation of replication initiation

Abe, Y., Shioi, S., Kita, S., Nakata, H., Maenaka, K., Kohda, D., Katayama, T. & Ueda, T., 11 2017, : : FEBS Letters. 591, 22, p. 3805-3816 12 p.

研究成果: ジャーナルへの寄稿レター

Crystal structure
X-Rays
X rays
Heat-Shock Proteins
Proteins
25 引用 (Scopus)

W-shape nucleic acid (WNA) for selective formation of non-natural anti-parallel triplex including a TA interrupting site

Sasaki, S., Yamauchi, H., Nagatsugi, F., Takahashi, R., Taniguchi, Y. & Maeda, M., 9 24 2001, : : Tetrahedron Letters. 42, 39, p. 6915-6918 4 p.

研究成果: ジャーナルへの寄稿記事

Nucleic Acids
Hydrogen
Hydrogen bonds
Bearings (structural)
Oligodeoxyribonucleotides
11 引用 (Scopus)

Wild-type p53 gene transfer: A novel therapeutic strategy for neointimal hyperplasia after arterial injury

Yonemitsu, Y., Kaneda, Y., Hata, Y., Nakashima, Y. & Sueishi, K., 1 1 1997, : : Annals of the New York Academy of Sciences. 811, p. 395-400 6 p.

研究成果: ジャーナルへの寄稿記事

Gene transfer
p53 Genes
Hyperplasia
Wounds and Injuries
Therapeutics
22 引用 (Scopus)

Whole-body kinetic image of a redox probe in mice using Overhauser-enhanced MRI

Kosem, N., Naganuma, T., Ichikawa, K., Phumala Morales, N., Yasukawa, K., Hyodo, F., Yamada, K. I. & Utsumi, H., 7 15 2012, : : Free Radical Biology and Medicine. 53, 2, p. 328-336 9 p.

研究成果: ジャーナルへの寄稿記事

Body Image
Magnetic resonance imaging
Oxidation-Reduction
Kinetics
Pharmacokinetics
16 引用 (Scopus)
Diacylglycerol Kinase
Phosphatidic Acids
Diglycerides
Phosphatidylinositols
Isoenzymes
2 引用 (Scopus)

What are barriers to pharmacogenomics (PGx) clinical uptake?

Ieiri, I., 1 1 2012, : : Drug metabolism and pharmacokinetics. 27, 3, 1 p.

研究成果: ジャーナルへの寄稿編集

Pharmacogenetics

Western blotting of steroidal alkaloid glycosides using monoclonal antibody against solamargine

Tanaka, H., Putalun, W. & Shoyama, Y., 1 1 1999, : : Journal of Liquid Chromatography and Related Technologies. 22, 10, p. 1503-1512 10 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
Alkaloids
Western Blotting
Monoclonal Antibodies
Bovine Serum Albumin
1 引用 (Scopus)

Western blotting of glycyrrhetinic acid glucuronides using anti-glycyrrhizin monoclonal antibody

Shan, S. J., Tanaka, H., Hayashi, J. & Shoyama, Y., 7 26 2001, : : Journal of Liquid Chromatography and Related Technologies. 24, 10, p. 1491-1499 9 p.

研究成果: ジャーナルへの寄稿記事

Glycyrrhetinic Acid
Glycyrrhizic Acid
Glucuronides
Western Blotting
Monoclonal Antibodies
9 引用 (Scopus)

Western blotting method for the immunostaining detection of glucuronides of glycyrrhetic acid using anti-glycyrrhizin monoclonal antibody

Shan, S. J., Tanaka, H. & Shoyama, Y., 1 1 1999, : : Biological and Pharmaceutical Bulletin. 22, 2, p. 221-223 3 p.

研究成果: ジャーナルへの寄稿記事

Glycyrrhetinic Acid
Glycyrrhizic Acid
Glucuronides
Western Blotting
Monoclonal Antibodies
26 引用 (Scopus)

Western blotting for ginseng saponins, ginsenosides using anti- ginsenoside Rb1 monoclonal antibody

Fukuda, N., Tanaka, H. & Shoyama, Y., 2 1999, : : Biological and Pharmaceutical Bulletin. 22, 2, p. 219-220 2 p.

研究成果: ジャーナルへの寄稿記事

Ginsenosides
Panax
Saponins
Western Blotting
Monoclonal Antibodies
10 引用 (Scopus)

Water-proton relaxivity of hyperbranched polymers carrying TEMPO radicals

Hayashi, H., Karasawa, S., Tanaka, A., Odoi, K., Chikama, K., Kuribayashi, H. & Koga, N., 3 1 2009, : : Magnetic Resonance in Chemistry. 47, 3, p. 201-204 4 p.

研究成果: ジャーナルへの寄稿記事

Protons
Polymers
Spin-lattice relaxation
Water
Relaxation time
4 引用 (Scopus)

Water-Proton Relaxivities of Radical Nanoparticles Self-Assembled via Hydration or Dehydration Processes

Morishita, K., Okamoto, Y., Murayama, S., Usui, K., Ohashi, E., Hirai, G., Aoki, I. & Karasawa, S., 8 8 2017, : : Langmuir. 33, 31, p. 7810-7817 8 p.

研究成果: ジャーナルへの寄稿記事

Dehydration
dehydration
Hydration
hydration
Protons
13 引用 (Scopus)

Water-proton relaxivities of DNA oligomers carrying TEMPO radicals

Sato, Y., Hayashi, H., Okazaki, M., Aso, M., Karasawa, S., Ueki, S., Suemune, H. & Koga, N., 11 1 2008, : : Magnetic Resonance in Chemistry. 46, 11, p. 1055-1058 4 p.

研究成果: ジャーナルへの寄稿記事

Oligomers
Paramagnetic resonance
Protons
DNA
Water
18 引用 (Scopus)

Warfarin-dosing algorithm based on a population pharmacokinetic/ pharmacodynamic model combined with Bayesian forecasting

Sasaki, T., Tabuchi, H., Higuchi, S. & Ieiri, I., 12 2 2009, : : Pharmacogenomics. 10, 8, p. 1257-1266 10 p.

研究成果: ジャーナルへの寄稿記事

Warfarin
International Normalized Ratio
Pharmacokinetics
Population
Prothrombin Time
4 引用 (Scopus)

Vulnerability of synaptic plasticity in the striatum of methamphetamine-sensitized rats

Arai, I., Shimazoe, T., Yoshimatsu, A., Inoue, H., Shibata, S. & Watanabe, S., 9 1 1998, : : Japanese Journal of Pharmacology. 78, 1, p. 105-108 4 p.

研究成果: ジャーナルへの寄稿記事

Neuronal Plasticity
Methamphetamine
Ischemia
Corpus Striatum
Dopamine
8 引用 (Scopus)

Voltage-dependent N-type Ca2+ channels in endothelial cells contribute to oxidative stress-related endothelial dysfunction induced by angiotensin II in mice

Nishida, M., Ishikawa, T., Saiki, S., Sunggip, C., Aritomi, S., Harada, E., Kuwahara, K., Hirano, K., Mori, Y. & Kim-Mitsuyama, S., 5 3 2013, : : Biochemical and Biophysical Research Communications. 434, 2, p. 210-216 7 p.

研究成果: ジャーナルへの寄稿記事

Oxidative stress
Endothelial cells
Angiotensin II
Oxidative Stress
Endothelial Cells
27 引用 (Scopus)

Vitamin C improves attenuated angiotensin II-induced endothelium-dependent vasodilation in human forearm vessels

Hirooka, Y., Eshima, K., Setoguchi, S., Kishi, T., Egashira, K. & Takeshita, A., 12 1 2003, : : Hypertension Research. 26, 12, p. 953-959 7 p.

研究成果: ジャーナルへの寄稿記事

Forearm
Vasodilation
Angiotensin II
Ascorbic Acid
Endothelium
16 引用 (Scopus)

Visual detection of saikosaponins by on-membrane immunoassay and estimation of traditional Chinese medicines containing Bupleuri radix

Morinaga, O., Zhu, S., Tanaka, H. & Shoyama, Y., 8 4 2006, : : Biochemical and Biophysical Research Communications. 346, 3, p. 687-692 6 p.

研究成果: ジャーナルへの寄稿記事

Chinese Traditional Medicine
Immunoassay
Medicine
Membranes
saikosaponin
32 引用 (Scopus)

VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B

Onimaru, M., Yonemitsu, Y., Fujii, T., Tanii, M., Nakano, T., Nakagawa, K., Kohno, R. I., Hasegawa, M., Nishikawa, S. I. & Sueishi, K., 11 1 2009, : : American Journal of Physiology - Heart and Circulatory Physiology. 297, 5, p. H1685-H1696

研究成果: ジャーナルへの寄稿記事

Proto-Oncogene Proteins c-sis
Lymphangiogenesis
Vascular Endothelial Growth Factor C
Fibroblast Growth Factor 2
Endothelial Cells
4 引用 (Scopus)

Vasospastic angina in patients with systemic triglyceride storage disease with Jordans' anomaly and cardiomyopathy

Ando, S. I., Usui, M., Matsumoto, T., Egashira, K., Takeshita, A., Terasaki, F., Deguchi, H. & Kawamura, K., 4 11 1996, : : JAPANESE CIRCULATION JOURNAL. 60, 2, p. 124-129 6 p.

研究成果: ジャーナルへの寄稿記事

Jordan
Cardiomyopathies
Triglycerides
Chest Pain
Siblings
30 引用 (Scopus)

Vasculoprotective role of inducible nitric oxide synthase at inflammatory coronary lesions induced by chronic treatment with interleukin- 1β in pigs in vivo

Fukumoto, Y., Shimokawa, H., Kozai, T., Kadokami, T., Kuwata, K., Yonemitsu, Y., Kuga, T., Egashira, K., Sueishi, K. & Takeshita, A., 11 4 1997, : : Circulation. 96, 9, p. 3104-3111 8 p.

研究成果: ジャーナルへの寄稿記事

Nitric Oxide Synthase Type II
Interleukin-1
Nitric Oxide Synthase
Swine
Coronary Vessels
130 引用 (Scopus)

Vascular endothelial growth factor is necessary in the development of arteriosclerosis by recruiting/activating monocytes in a rat model of long-term inhibition of nitric oxide synthesis

Zhao, Q., Egashira, K., Inoue, S., Usui, M., Kitamoto, S., Ni, W., Ishibashi, M., Hiasa, K. I., Ichiki, T., Shibuya, M. & Takeshita, A., 3 5 2002, : : Circulation. 105, 9, p. 1110-1115 6 p.

研究成果: ジャーナルへの寄稿記事

Arteriosclerosis
Vascular Endothelial Growth Factor A
Monocytes
Nitric Oxide
Blood Vessels
10 引用 (Scopus)

Vascular endothelial growth factor - Basic science and its clinical implications

Celec, P. & Yonemitsu, Y., 10 1 2004, : : Pathophysiology. 11, 2, p. 69-75 7 p.

研究成果: ジャーナルへの寄稿記事

Vascular Endothelial Growth Factor A
Physiological Phenomena
Coronary Artery Disease
Therapeutics
Research