研究成果 1976 2020

2018
10 引用 (Scopus)

Chemoselective Catalytic Dehydrogenative Cross-Coupling of 2-Acylimidazoles: Mechanistic Investigations and Synthetic Scope

Tanaka, T., Hashiguchi, K., Tanaka, T., Yazaki, R. & Ohshima, T., 9 7 2018, : : ACS Catalysis. 8, 9, p. 8430-8440 11 p.

研究成果: ジャーナルへの寄稿記事

phosphine
Carbon
Iron
Chemical activation
Alkanes
1 引用 (Scopus)

Chronopharmacology based on molecular clock

Ohdo, S., 1 1 2018, : : Oral Therapeutics and Pharmacology. 37, 1, p. 1-8 8 p.

研究成果: ジャーナルへの寄稿記事

Genes
Drug Therapy
Pharmaceutical Preparations
Sleep
Chronotherapy
1 引用 (Scopus)

Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function /631/80/105 /631/208/199 /38 /38/35 /38/109 /38/77 /13/51 /13/109 article

Tsurudome, Y., Satoru, K., Kanemitsu, T., Katamune, C., Oda, M., Kanado, Y., Kato, M., Morita, A., Tahara, Y., Naoya, M., Shibata, S. & Ohdo, S., 12 1 2018, : : Scientific reports. 8, 1, 9072.

研究成果: ジャーナルへの寄稿記事

Circadian Clocks
Fatty Acid Transport Proteins
Liver
Transcriptional Activation
Membrane Proteins
17 引用 (Scopus)

Clinical significance of programmed cell death-ligand 1 expression and the immune microenvironment at the invasive front of colorectal cancers with high microsatellite instability

Korehisa, S., Oki, E., Iimori, M., Nakaji, Y., Shimokawa, M., Saeki, H., Okano, S., Oda, Y. & Maehara, Y., 2 15 2018, : : International Journal of Cancer. 142, 4, p. 822-832 11 p.

研究成果: ジャーナルへの寄稿記事

Microsatellite Instability
Colorectal Neoplasms
Cell Death
Ligands
CD274 Antigen
1 引用 (Scopus)

Clinical Significance of the Wild Type p53-Induced Phosphatase 1 Expression in Invasive Breast Cancer

Inoue, Y., Yamashita, N., Kitao, H., Tanaka, K., Saeki, H., Oki, E., Oda, Y., Tokunaga, E. & Maehara, Y., 8 2018, : : Clinical Breast Cancer. 18, 4, p. e643-e650

研究成果: ジャーナルへの寄稿記事

Protein Phosphatase 1
Phosphoric Monoester Hydrolases
Phosphoprotein Phosphatases
Magnesium
Breast Neoplasms
5 引用 (Scopus)

Complex formation between the vasopressin 1b receptor, β-arrestin-2, and the μ-opioid receptor underlies morphine tolerance

Koshimizu, T. A., Honda, K., Nagaoka-Uozumi, S., Ichimura, A., Kimura, I., Michio, N., Sakai, N., Shibata, K., Ushijima, K., Fujimura, A., Hirasawa, A., Kurose, H., Tsujimoto, G., Tanoue, A. & Takano, Y., 6 1 2018, : : Nature Neuroscience. 21, 6, p. 820-833 14 p.

研究成果: ジャーナルへの寄稿記事

Vasopressin Receptors
Opioid Receptors
Morphine
Vasopressins
Adenylyl Cyclases
5 引用 (Scopus)
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Connexins
varespladib methyl
Astrocytes
Parkinson Disease
1 引用 (Scopus)

Contribution of the clock gene DEC2 to VEGF mRNA upregulation by modulation of HIF1α protein levels in hypoxic MIO-M1 cells, a human cell line of retinal glial (Müller) cells

Kusunose, N., Akamine, T., Kobayashi, Y., Yoshida, S., Kimoto, K., Yasukochi, S., Matsunaga, N., Koyanagi, S., Ohdo, S. & Kubota, T., 1 1 2018, (受理済み/印刷中) : : Japanese Journal of Ophthalmology.

研究成果: ジャーナルへの寄稿記事

Neuroglia
Vascular Endothelial Growth Factor A
Up-Regulation
Cell Line
Messenger RNA
1 引用 (Scopus)

Correction to: Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites (Journal of Natural Medicines, (2018), 72, 1, (32-42), 10.1007/s11418-017-1144-z)

Sakamoto, S., Putalun, W., Vimolmangkang, S., Phoolcharoen, W., Shoyama, Y., Tanaka, H. & Morimoto, S., 1 1 2018, : : Journal of Natural Medicines. 72, 1, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Immunosorbents
Metabolites
Internet
Medicine
Assays

Crystallization of Human Erythrocyte Band 3, the anion exchanger, at the International Space Station “KIBO”

Hatae, H., Inaka, K., Okamura, R., Furubayashi, N., Kamo, M., Kobayashi, T., Abe, Y., Iwata, S. & Hamasaki, N., 10 15 2018, : : Analytical Biochemistry. 559, p. 91-93 3 p.

研究成果: ジャーナルへの寄稿記事

Chloride-Bicarbonate Antiporters
Space stations
Crystallization
Blood
Erythrocytes
6 引用 (Scopus)

D-Amino acids in molecular evolution in space – Absolute asymmetric photolysis and synthesis of amino acids by circularly polarized light

Sugahara, H., Meinert, C., Nahon, L., Jones, N. C., Hoffmann, S. V., Hamase, K., Takano, Y. & Meierhenrich, U. J., 7 1 2018, : : Biochimica et Biophysica Acta - Proteins and Proteomics. 1866, 7, p. 743-758 16 p.

研究成果: ジャーナルへの寄稿評論記事

Molecular Evolution
Photolysis
Light polarization
Light
Amino Acids

Detection and inhibition of redox reaction and lipid derived radicals

Yamada, K-I., 1 1 2018, : : Drug Delivery System. 33, 3, p. 197-203 7 p.

研究成果: ジャーナルへの寄稿記事

Oxidation-Reduction
Lipids
Free Radicals
Animal Models
Carcinogenesis

Development of a colloidal gold nanoparticle-based immunochromatographic strip for the one-step detection of miroestrol and puerarin

Krittanai, S., Kitisripanya, T., Udomsin, O., Tanaka, H., Sakamoto, S., Juengwatanatrakul, T. & Putalun, W., 11 1 2018, : : Biomedical Chromatography. 32, 11, e4330.

研究成果: ジャーナルへの寄稿記事

Gold Colloid
Nanoparticles
Pueraria
Rejuvenation
Immunosorbents

Development of a Competitive Time-Resolved Fluoroimmunoassay for Paclitaxel

Cui, Q., Tanaka, H., Shoyama, Y., Ye, H. T., Li, F., Tian, E. W., Wu, Y. S. & Chao, Z., 5 1 2018, : : Phytochemical Analysis. 29, 3, p. 284-289 6 p.

研究成果: ジャーナルへの寄稿記事

Fluoroimmunoassay
paclitaxel
Taxus
taxes
Paclitaxel
3 引用 (Scopus)

Development of an immunochromatographic strip incorporating anti-mitragynine monoclonal antibody conjugated to colloidal gold for kratom alkaloids detection

Limsuwanchote, S., Putalun, W., Tanaka, H., Morimoto, S., Keawpradub, N. & Wungsintaweekul, J., 7 1 2018, : : Drug Testing and Analysis. 10, 7, p. 1168-1175 8 p.

研究成果: ジャーナルへの寄稿記事

Gold Colloid
alkaloid
Alkaloids
antibody
gold
8 引用 (Scopus)
Amino Acids
Fluids
Liquids
High Pressure Liquid Chromatography
L Forms
1 引用 (Scopus)
Carbonyl compounds
Rhodium
Catalysts
Proton transfer
Thalidomide
1 引用 (Scopus)

Diacylglycerol kinase β induces filopodium formation via its C1, catalytic and carboxy-terminal domains and interacts with the Rac1-GTPase-activating protein, β2-chimaerin

Maeda, Y., Shibata, K., Akiyama, R., Murakami, Y., Takao, S., Murakami, C., Takahashi, D., Sakai, H. & Sakane, F., 9 26 2018, : : Biochemical and Biophysical Research Communications. 504, 1, p. 54-60 7 p.

研究成果: ジャーナルへの寄稿記事

Diacylglycerol Kinase
GTPase-Activating Proteins
Pseudopodia
Cell membranes
Spine
2 引用 (Scopus)

Different expression systems resulted in varied binding properties of anti-paclitaxel single-chain variable fragment antibody clone 1C2

Yusakul, G., Sakamoto, S., Nuntawong, P., Tanaka, H. & Morimoto, S., 1 1 2018, : : Journal of Natural Medicines. 72, 1, p. 310-316 7 p.

研究成果: ジャーナルへの寄稿記事

Single-Chain Antibodies
Paclitaxel
Bombyx
Clone Cells
Escherichia coli
6 引用 (Scopus)

Dimethyl fumarate ameliorates chemotherapy agent-induced neurotoxicity in vitro

kawashiri, T., Miyagi, A., Shimizu, S., Shigematsu, N., Kobayashi, D. & Shimazoe, T., 6 1 2018, : : Journal of Pharmacological Sciences. 137, 2, p. 202-211 10 p.

研究成果: ジャーナルへの寄稿記事

oxaliplatin
Drug Therapy
Fumarates
PC12 Cells
Cultured Cells
3 引用 (Scopus)

Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1

Tashiro, S., Caaveiro, J. M. M., Nakakido, M., Tanabe, A., Nagatoishi, S., Tamura, Y., Matsuda, N., Liu, D., Hoang, Q. Q. & Tsumoto, K., 9 21 2018, : : ACS Chemical Biology. 13, 9, p. 2783-2793 11 p.

研究成果: ジャーナルへの寄稿記事

X Ray Crystallography
Oxidation-Reduction
Disease Progression
X ray crystallography
Assays
9 引用 (Scopus)

DNA replication stress and cancer chemotherapy

Kitao, H., Iimori, M., Kataoka, Y., Wakasa, T., Tokunaga, E., Saeki, H., Oki, E. & Maehara, Y., 2 1 2018, : : Cancer Science. 109, 2, p. 264-271 8 p.

研究成果: ジャーナルへの寄稿評論記事

DNA Replication
Drug Therapy
Neoplasms
Biological Phenomena
Genomic Instability
1 引用 (Scopus)

Editorial: Neuroglia molecular mechanisms in psychiatric disorders

Scuderi, C., Noda, M. & Verkhratsky, A., 10 31 2018, : : Frontiers in Molecular Neuroscience. 11, 407.

研究成果: ジャーナルへの寄稿編集

Oligodendroglia
Microglia
Neuroglia
Astrocytes
Psychiatry
1 引用 (Scopus)

Effects of Derinat on ischemia-reperfusion-induced pressure ulcer mouse model

Liu, J., Rybakina, E. G., Korneva, E. A. & Noda, M., 10 2018, : : Journal of Pharmacological Sciences. 138, 2, p. 123-130 8 p.

研究成果: ジャーナルへの寄稿記事

Pressure Ulcer
Reperfusion
Ischemia
Alprostadil
Salmon

Effects of using the adherence score sheet according to application timing in improving medication adherence in SETSUYAKU-BAG campaign

Kobayashi, D., Koyanagi, K., Kubota, T., Maruyama, M., Miisho, T., Kaneko, E., Kawanami, M., Kihara, T., Takaki, J., Nakashiba, T., Nagatomi, S., Seo, T., Tanaka, T. & Shimazoe, T., 1 1 2018, : : Yakugaku Zasshi. 138, 12, p. 1549-1559 11 p.

研究成果: ジャーナルへの寄稿記事

Medication Adherence
Pharmacists
Chronic Disease
Outpatients
Pharmacies
3 引用 (Scopus)
Plasma (human)
3-Hydroxybutyric Acid
High performance liquid chromatography
Lactic Acid
Enantiomers
2 引用 (Scopus)

Endogenous Membrane Receptor Labeling by Reactive Cytokines and Growth Factors to Chase Their Dynamics in Live Cells

Takaoka, Y., Uchinomiya, S., Kobayashi, D., Endo, M., Hayashi, T., Fukuyama, Y., Hayasaka, H., Miyasaka, M., Ueda, T., Shimada, I. & Hamachi, I., 6 14 2018, : : Chem. 4, 6, p. 1451-1464 14 p.

研究成果: ジャーナルへの寄稿記事

Labeling
Intercellular Signaling Peptides and Proteins
Cytokines
membrane
Membranes
1 引用 (Scopus)

Enhancement effect on the chemiluminescence of acridinium esters under neutral conditions

Nakazono, M. & Nanbu, S., 3 1 2018, : : Luminescence. 33, 2, p. 345-348 4 p.

研究成果: ジャーナルへの寄稿記事

Chemiluminescence
Luminescence
Esters
Acridines
Derivatives
22 引用 (Scopus)

Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites

Sakamoto, S., Putalun, W., Vimolmangkang, S., Phoolcharoen, W., Shoyama, Y., Tanaka, H. & Morimoto, S., 1 1 2018, : : Journal of Natural Medicines. 72, 1, p. 32-42 11 p.

研究成果: ジャーナルへの寄稿評論記事

Immunosorbents
Metabolites
Immunoassay
Assays
Enzyme-Linked Immunosorbent Assay
1 引用 (Scopus)

Enzyme linked immunosorbent assay for total potent estrogenic miroestrol and deoxymiroestrol of Pueraria candollei, a Thai herb for menopause remedy

Yusakul, G., Kitisripanya, T., Juengwatanatrakul, T., Sakamoto, S., Tanaka, H. & Putalun, W., 6 1 2018, : : Journal of Natural Medicines. 72, 3, p. 641-650 10 p.

研究成果: ジャーナルへの寄稿記事

Pueraria
Immunosorbents
Menopause
Assays
Enzyme-Linked Immunosorbent Assay

Epigenetic regulation of pharmacokinetic-related genes in human tissues

Hirota, T., 1 1 2018, : : Yakugaku Zasshi. 138, 11, p. 1391-1396 6 p.

研究成果: ジャーナルへの寄稿評論記事

Epigenomics
Pharmacokinetics
Breast Neoplasms
Pharmaceutical Preparations
Genes

Epithelial cell adhesion molecule expression in hepatic stem/progenitor cells is controlled by the molecular clock system

Kimura, H., Naoya, M., Kakimoto, K., Watanabe, M., Tsuruta, A., Kusunose, N., Shiromizu, S., Satoru, K. & Ohdo, S., 9 5 2018, : : Biochemical and Biophysical Research Communications. 503, 2, p. 1063-1069 7 p.

研究成果: ジャーナルへの寄稿記事

Liver Regeneration
Cell Adhesion Molecules
Stem cells
Clocks
Hepatocytes
10 引用 (Scopus)

Epithelial Paradox: Clinical Significance of Coexpression of E-cadherin and Vimentin With Regard to Invasion and Metastasis of Breast Cancer

Yamashita, N., Tokunaga, E., Iimori, M., Inoue, Y., Tanaka, K., Kitao, H., Saeki, H., Oki, E. & Maehara, Y., 10 2018, : : Clinical Breast Cancer. 18, 5, p. e1003-e1009

研究成果: ジャーナルへの寄稿記事

Vimentin
Cadherins
Breast Neoplasms
Neoplasm Metastasis
Neoplasms
2 引用 (Scopus)

Evaluation of simultaneous binding of Chromomycin A3 to the multiple sites of DNA by the new restriction enzyme assay

Murase, H., Noguchi, T. & Sasaki, S., 6 1 2018, : : Bioorganic and Medicinal Chemistry Letters. 28, 10, p. 1832-1835 4 p.

研究成果: ジャーナルへの寄稿記事

Chromomycin A3
DNA Restriction Enzymes
Enzyme Assays
Assays
DNA
3 引用 (Scopus)
diacylglycerol kinase
Diacylglycerol Kinase
Baculoviridae
Purification
Insects
1 引用 (Scopus)

Fluorescence tumor-imaging using a thermo-responsive molecule with an emissive aminoquinoline derivative

Araki, T., Fuchi, Y., Murayama, S., Shiraishi, R., Oyama, T., Aso, M., Aoki, I., Kobayashi, S., Yamada, K. I. & Karasawa, S., 10 2 2018, : : Nanomaterials. 8, 10, 782.

研究成果: ジャーナルへの寄稿記事

Aminoquinolines
Tumors
Fluorescence
Derivatives
Imaging techniques
13 引用 (Scopus)
Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., 7 27 2018, : : Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

研究成果: ジャーナルへの寄稿記事

Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome
3 引用 (Scopus)

Genotoxic Responses of Mitochondrial Oxygen Consumption Rate and Mitochondrial Semiquinone Radicals in Tumor Cells

Yamamoto, K., Yasui, H., Bo, T., Yamamori, T., Hiraoka, W., Yamasaki, T., Yamada, K-I. & Inanami, O., 8 1 2018, : : Applied Magnetic Resonance. 49, 8, p. 837-851 15 p.

研究成果: ジャーナルへの寄稿記事

oxygen consumption
electron paramagnetic resonance
respiration
tumors
mitochondria
6 引用 (Scopus)

Gliotransmitters and cytokines in the control of blood-brain barrier permeability

Osipova, E. D., Semyachkina-Glushkovskaya, O. V., Morgun, A. V., Pisareva, N. V., Malinovskaya, N. A., Boitsova, E. B., Pozhilenkova, E. A., Belova, O. A., Salmin, V. V., Taranushenko, T. E., Noda, M. & Salmina, A. B., 7 26 2018, : : Reviews in the Neurosciences. 29, 5, p. 567-591 25 p.

研究成果: ジャーナルへの寄稿記事

Blood-Brain Barrier
Permeability
Cytokines
Neuroglia
Amino Acid Transport System X-AG

Green Pharma: A new strategy for drug discovery in academia by targeting glial cells and ATP receptors

Yamashita, T., Makoto, T., Saitoh, H. & Inoue, K., 1 1 2018, : : Yakugaku Zasshi. 138, 8, p. 1027-1031 5 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Drug Discovery
Neuroglia
Hyperalgesia
Neuralgia

Growth suppression of human colorectal cancer cells with mutated KRAS by 3-deaza-cytarabine in 3d floating culture

Luo, H., Nishi, K., Ishikura, S., Swain, A., Morishige, N., Yazaki, R., Ohshima, T., Shirasawa, S. & Tsunoda, T., 7 1 2018, : : Anticancer research. 38, 7, p. 4247-4256 10 p.

研究成果: ジャーナルへの寄稿記事

Cytarabine
Colorectal Neoplasms
Uridine
Growth
gemcitabine
2 引用 (Scopus)

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., 8 1 2018, : : Journal of Cell Science. 131, 15

研究成果: ジャーナルへの寄稿記事

Ribosomal Proteins
Proteasome Endopeptidase Complex
Ubiquitin
Glutamic Acid
Down-Regulation
1 引用 (Scopus)

Gut microbiota-derived D-serine protects against acute kidney injury

Nakade, Y., Iwata, Y., Furuichi, K., Mita, M., Hamase, K., Konno, R., Miyake, T., Sakai, N., Kitajima, S., Toyama, T., Shinozaki, Y., Sagara, A., Miyagawa, T., Hara, A., Shimizu, M., Kamikawa, Y., Sato, K., Oshima, M., Yoneda-Nakagawa, S., Yamamura, Y. および8人, Kaneko, S., Miyamoto, T., Katane, M., Homma, H., Morita, H., Suda, W., Hattori, M. & Wada, T., 10 18 2018, : : JCI Insight. 3, 20

研究成果: ジャーナルへの寄稿記事

公開
Acute Kidney Injury
Serine
Kidney
Amino Acids
Dysbiosis
2 引用 (Scopus)

12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration

Kim, T. H., Yang, Y. M., Han, C. Y., Koo, J. H., Oh, H., Kim, S. S., You, B. H., Choi, Y. H., Park, T. S., Lee, C. H., Kurose, H., Noureddin, M., Seki, E., Wan, Y. J. Y., Choi, C. S. & Kim, S. G., 12 3 2018, : : Journal of Clinical Investigation. 128, 12, p. 5587-5602 16 p.

研究成果: ジャーナルへの寄稿記事

Sirtuin 1
Fatty Liver
Ubiquitin
GTP-Binding Proteins
Respiration
10 引用 (Scopus)

Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated myocardial senescence

Nishimura, A., Shimauchi, T., Tanaka, T., Shimoda, K., Toyama, T., Kitajima, N., Ishikawa, T., Shindo, N., Numaga-Tomita, T., Yasuda, S., Sato, Y., Kuwahara, K., Kumagai, Y., Akaike, T., Ide, T., Ojida, A., Mori, Y. & Nishida, M., 11 13 2018, : : Science Signaling. 11, 556, eaat5185.

研究成果: ジャーナルへの寄稿記事

Filamins
Dynamins
Actins
Mitochondrial Dynamics
Proteins

Imaging Doxorubicin Free Radical in Mice with Overhauser Enhanced MRI and its Tumor Suppression Effect in Mice

Kato, N., Sato, S., Yamada, K-I. & Ichikawa, K., 8 1 2018, : : Applied Magnetic Resonance. 49, 8, p. 869-879 11 p.

研究成果: ジャーナルへの寄稿記事

free radicals
mice
tumors
retarding
magnetic resonance
2 引用 (Scopus)
Antigens
Paclitaxel
Antibodies
Immunoglobulin G
Light
Amyloid
Light
Amyloidosis
epigallocatechin gallate
Oxidation