研究成果 1976 2020

2017
1 引用 (Scopus)

Development of damaged nucleoside mimics for inhibition of their repair enzymes

Taniguchi, Y., 1 1 2017, : : Yakugaku Zasshi. 137, 3, p. 293-300 8 p.

研究成果: ジャーナルへの寄稿記事

Nucleosides
Enzymes
Hydrolysis
Nucleotides
Neoplasms
19 引用 (Scopus)

D -Glutamate is metabolized in the heart mitochondria

Ariyoshi, M., Katane, M., Hamase, K., Miyoshi, Y., Nakane, M., Hoshino, A., Okawa, Y., Mita, Y., Kaimoto, S., Uchihashi, M., Fukai, K., Ono, K., Tateishi, S., Hato, D., Yamanaka, R., Honda, S., Fushimura, Y., Iwai-Kanai, E., Ishihara, N., Mita, M. および2人, Homma, H. & Matoba, S., 3 7 2017, : : Scientific reports. 7, 43911.

研究成果: ジャーナルへの寄稿記事

Heart Mitochondria
Glutamic Acid
glutamate racemase
Amino Acids
Proline
1 引用 (Scopus)
Dietary Supplements
Glucocorticoids
Chickens
Circadian Clocks
Metabolic Syndrome X
6 引用 (Scopus)

Dioleoyl-phosphatidic acid selectively binds to α-synuclein and strongly induces its aggregation

Mizuno, S., Sasai, H., Kume, A., Takahashi, D., Satoh, M., Kado, S. & Sakane, F., 3 2017, : : FEBS Letters. 591, 5, p. 784-791 8 p.

研究成果: ジャーナルへの寄稿記事

Synucleins
Phosphatidic Acids
Agglomeration
Endopeptidase K
Proteins
7 引用 (Scopus)

Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration

Takeda, T., Komiya, Y., Koga, T., Ishida, T., Ishii, Y., Kikuta, Y., Nakaya, M., Kurose, H., Yokomizo, T., Shimizu, T., Uchi, H., Furue, M. & Yamada, H., 1 1 2017, : : Journal of Biological Chemistry. 292, 25, p. 10586-10599 14 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Receptors
Dioxins
Leukotriene B4
Neutrophil Infiltration
Biosynthesis
13 引用 (Scopus)
Proton transfer
Carboxylic Acids
Carboxylic acids
Amines
propargylamine
13 引用 (Scopus)
Amino acids
Esters
Amino Acids
Nucleophiles
Addition reactions
41 引用 (Scopus)

Direct Catalytic Alcoholysis of Unactivated 8-Aminoquinoline Amides

Deguchi, T., Xin, H. L., Morimoto, H. & Ohshima, T., 5 5 2017, : : ACS Catalysis. 7, 5, p. 3157-3161 5 p.

研究成果: ジャーナルへの寄稿記事

Amides
Functional groups
Esters
Alcohols
Catalysts
3 引用 (Scopus)

Direct enantioselective alkynylation of α-ketoesters and α-ketiminoesters catalyzed by [bis(oxazoline)phenyl]rhodium(III) complexes

Morisaki, K., Morimoto, H., Mashima, K. & Ohshima, T., 1 1 2017, : : Heterocycles. 95, 2, p. 637-661 25 p.

研究成果: ジャーナルへの寄稿記事

Rhodium
Aldehydes
Protons
Catalysts
Proton transfer
1 引用 (Scopus)

Discovery of highly reactive peptide tag by ELISA-type screening for specific cysteine conjugation

Kurashige, N., Fuchida, H., Tabata, S., Uchinomiya, S. & Ojida, A., 4 18 2017, (受理済み/印刷中) : : Bioorganic and Medicinal Chemistry Letters.

研究成果: ジャーナルへの寄稿記事

Cysteine
Screening
Enzyme-Linked Immunosorbent Assay
Peptides
Labeling
14 引用 (Scopus)

DNA replication origins and fork progression at mammalian telomeres

Higa, M., Fujita, M. & Yoshida, K., 4 2017, : : Genes. 8, 4, 112.

研究成果: ジャーナルへの寄稿評論記事

Replication Origin
Telomere
DNA Replication
Chromosomal Instability
Proteins
2 引用 (Scopus)

Dysfunction of the circadian transcriptional factor CLOCK in mice resists chemical carcinogen-induced tumorigenesis

Hashikawa, K. I., Katamune, C., Kusunose, N., Matsunaga, N., Koyanagi, S. & Ohdo, S., 12 1 2017, : : Scientific reports. 7, 1, 9995.

研究成果: ジャーナルへの寄稿記事

Carcinogens
Carcinogenesis
Epidermal Growth Factor Receptor
Physiological Phenomena
Neoplasms
1 引用 (Scopus)

Eco-pharma of approved drug focused on mitochondria fission

Shimauchi, T., Nishimura, A., Ishikawa, T. & Nishida, M., 1 1 2017, : : Folia Pharmacologica Japonica. 149, 6, p. 269-273 5 p.

研究成果: ジャーナルへの寄稿コメント/討論

Drug Repositioning
Mitochondrial Dynamics
Drug Approval
Cell Aging
Mitochondria
1 引用 (Scopus)

Editorial: Role of protein-protein interactions in metabolism: Genetics, structure, function

Pandey, A. V., Henderson, C. J., Ishii, Y., Kranendonk, M., Backes, W. L. & Zanger, U. M., 11 27 2017, : : Frontiers in Pharmacology. 8, NOV, 881.

研究成果: ジャーナルへの寄稿編集

Genetic Structures
Cytochrome P-450 Enzyme System
Proteins

Effect of medical educational lectures by pharmacists for understanding and relieving post-laryngectomy symptoms

Hyoguchi, N., Kubota, T., Kobayashi, D. & Shimazoe, T., 1 1 2017, : : Yakugaku Zasshi. 137, 1, p. 83-93 11 p.

研究成果: ジャーナルへの寄稿記事

Laryngectomy
Pharmacists
Medicine
Health
Communication Barriers
3 引用 (Scopus)
Epidemiologic Effect Modifiers
Substitution reactions
Derivatives
Hydrogen bonds
Protonation
4 引用 (Scopus)

Epigenetic regulation of drug transporter expression in human tissues

Hirota, T., Tanaka, T., Takesue, H. & Ieiri, I., 1 2 2017, : : Expert Opinion on Drug Metabolism and Toxicology. 13, 1, p. 19-30 12 p.

研究成果: ジャーナルへの寄稿評論記事

Drug and Narcotic Control
Epigenomics
Tissue
Pharmaceutical Preparations
Genes
4 引用 (Scopus)

Evaluation of Teicoplanin Trough Values After the Recommended Loading Dose in Children With Associated Safety Analysis

Yamada, T., Kubota, T., Yonezawa, M., Nishio, H., Kanno, S., Yano, T., Kobayashi, D., Egashira, N., Takada, H., Hara, T. & Masuda, S., 4 1 2017, : : Pediatric Infectious Disease Journal. 36, 4, p. 398-400 3 p.

研究成果: ジャーナルへの寄稿記事

Teicoplanin
Safety
Kidney
Creatinine
Liver
8 引用 (Scopus)

Excessive spinal glutamate transmission is involved in oxaliplatin-induced mechanical allodynia: A possibility for riluzole as a prophylactic drug

Yamamoto, S., Ushio, S., Egashira, N., Kawashiri, T., Mitsuyasu, S., Higuchi, H., Ozawa, N., Masuguchi, K., Ono, Y. & Masuda, S., 12 1 2017, : : Scientific reports. 7, 1, 9661.

研究成果: ジャーナルへの寄稿記事

oxaliplatin
Riluzole
Hyperalgesia
Glutamic Acid
Pharmaceutical Preparations
8 引用 (Scopus)

Exponential propagation of large circular DNA by reconstitution of a chromosome-replication cycle

Su’etsugu, M., Takada, H., Katayama, T. & Tsujimoto, H., 1 1 2017, : : Nucleic acids research. 45, 20, p. 11525-11534 10 p.

研究成果: ジャーナルへの寄稿記事

Circular DNA
Organism Cloning
Chromosomes
Replication Origin
DNA
10 引用 (Scopus)

Exposure to electrophiles impairs reactive persulfide-dependent redox signaling in neuronal cells

Ihara, H., Kasamatsu, S., Kitamura, A., Nishimura, A., Tsutsuki, H., Ida, T., Ishizaki, K., Toyama, T., Yoshida, E., Hamid, H. A., Jung, M., Matsunaga, T., Fujii, S., Sawa, T., Nishida, M., Kumagai, Y. & Akaike, T., 1 1 2017, : : Chemical Research in Toxicology. 30, 9, p. 1673-1684 12 p.

研究成果: ジャーナルへの寄稿記事

Oxidation-Reduction
Chemical activation
Wounds and Injuries
Metabolites
Sulfhydryl Compounds

Expression of a Vibrio parahaemolyticus toxin in Escherichia coli results in chromosomal DNA degradation

Zhang, J., Taniguchi, S., Ito, H., Iiyama, K., Hino, M., Katayama, T. & Kimura, M., 1 1 2017, : : Bioscience, Biotechnology and Biochemistry. 81, 10, p. 1937-1940 4 p.

研究成果: ジャーナルへの寄稿記事

Vibrio parahaemolyticus
Escherichia coli
Genes
Antitoxins
Degradation
1 引用 (Scopus)

Feasibility of magnetic resonance redox imaging at low magnetic field: Comparison at 1 T and 7 T

Nakamura, M., Shibata, S., Yamasaki, T., Ueno, M., Nakanishi, I., Matsumoto, K. I., Kamada, T., Yamada, K. I. & Aoki, I., 1 1 2017, : : American Journal of Translational Research. 9, 10, p. 4481-4491 11 p., AJTR0054131.

研究成果: ジャーナルへの寄稿記事

Magnetic resonance
Magnetic Fields
Oxidation-Reduction
Magnetic Resonance Imaging
Magnetic fields

Fibroblast growth factor in extremities

Tanaka, M. & Yonemitsu, Y., 7 11 2017, Therapeutic Angiogenesis. Springer Singapore, p. 145-158 14 p.

研究成果: 著書/レポートタイプへの貢献

Fibroblasts
Gene therapy
Gene transfer
Intercellular Signaling Peptides and Proteins
Viruses
8 引用 (Scopus)

Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells

Ohgidani, M., Kato, T. A., Hosoi, M., Tsuda, M., Hayakawa, K., Hayaki, C., Iwaki, R., Sagata, N., Hashimoto, R., Inoue, K., Sudo, N. & Kanba, S., 12 1 2017, : : Scientific reports. 7, 1, 11882.

研究成果: ジャーナルへの寄稿記事

Translational Medical Research
Fibromyalgia
Microglia
Tumor Necrosis Factor-alpha
Adenosine Triphosphate
9 引用 (Scopus)

Fluorescence Sensing of Inorganic Phosphate and Pyrophosphate Using Small Molecular Sensors and Their Applications

Wongkongkatep, J., Ojida, A. & Hamachi, I., 4 1 2017, : : Topics in Current Chemistry. 375, 2, 30.

研究成果: ジャーナルへの寄稿評論記事

Fluorescence
Phosphates
Sensors
Chemical reactions
Quenching
7 引用 (Scopus)

Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane

Rujas, E., Insausti, S., García-Porras, M., Sánchez-Eugenia, R., Tsumoto, K., Nieva, J. L. & Caaveiro, J. M. M., 4 21 2017, : : Journal of Molecular Biology. 429, 8, p. 1213-1226 14 p.

研究成果: ジャーナルへの寄稿記事

Neutralizing Antibodies
HIV-1
Membranes
AIDS Vaccines
Epitopes
9 引用 (Scopus)

Glycosylation of IgG-Fc: A molecular perspective

Kiyoshi, M., Tsumoto, K., Ishii-Watabe, A. & Martinez Caaveiro, J. M., 7 1 2017, : : International Immunology. 29, 7, p. 311-317 7 p.

研究成果: ジャーナルへの寄稿評論記事

Glycosylation
Polysaccharides
Immunoglobulin G
Antibodies
Immunoglobulin Isotypes
4 引用 (Scopus)

GRWD1, a new player among oncogenesis-related ribosomal/nucleolar proteins

Takafuji, T., Kayama, K., Sugimoto, N. & Fujita, M., 8 3 2017, : : Cell Cycle. 16, 15, p. 1397-1403 7 p.

研究成果: ジャーナルへの寄稿評論記事

Ribosomal Proteins
Nuclear Proteins
Carcinogenesis
Neoplasms
Protein Biosynthesis
11 引用 (Scopus)

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kayama, K., Watanabe, S., Takafuji, T., Tsuji, T., Hironaka, K., Matsumoto, M., Nakayama, K. I., Enari, M., Kohno, T., Shiraishi, K., Kiyono, T., Yoshida, K., Sugimoto, N. & Fujita, M., 1 1 2017, : : EMBO Reports. 18, 1, p. 123-137 15 p.

研究成果: ジャーナルへの寄稿記事

Glutamic Acid
Carcinogenesis
Ligases
Ubiquitin
WD40 Repeats
3 引用 (Scopus)

Haemolytic actinoporins interact with carbohydrates using their lipid-binding module

Tanaka, K., Martinez Caaveiro, J. M., Morante, K. & Tsumoto, K., 1 1 2017, : : Philosophical Transactions of the Royal Society B: Biological Sciences. 372, 1726, 20160216.

研究成果: ジャーナルへの寄稿記事

toxins
Carbohydrates
carbohydrates
Polysaccharides
Lipids
1 引用 (Scopus)

Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a)

Homma, T., Akihara, R., Okano, S., Shichiri, M., Yoshida, Y., Yamada, K-I., Miyata, S., Nakajima, O. & Fujii, J., 2 15 2017, : : Behavioural Brain Research. 319, p. 219-224 6 p.

研究成果: ジャーナルへの寄稿記事

Ascorbic Acid
Aggression
Aldehyde Reductase
carbonyl reductase (NADPH)
Social Behavior
12 引用 (Scopus)

Heterogeneity of D-serine distribution in the human central nervous system

Suzuki, M., Imanishi, N., Mita, M., Hamase, K., Aiso, S. & Sasabe, J., 5 1 2017, : : ASN Neuro. 9, 3

研究成果: ジャーナルへの寄稿記事

Serine
Central Nervous System
Cerebrum
4 alpha-glucanotransferase
Neurophysiology
6 引用 (Scopus)

High ubiquitin-specific protease 44 expression induces DNA aneuploidy and provides independent prognostic information in gastric cancer

Nishimura, S., Oki, E., Ando, K., Iimori, M., Nakaji, Y., Nakashima, Y., Saeki, H., Oda, Y. & Maehara, Y., 6 2017, : : Cancer Medicine. 6, 6, p. 1453-1464 12 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin-Specific Proteases
Aneuploidy
Stomach Neoplasms
DNA
Chromosomal Instability
5 引用 (Scopus)

Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress

Wu, C. Y., Hsu, W. L., Tsai, M. H., Liang, J. L., Lu, J. H., Yen, C. J., Yu, H. S., Noda, M., Lu, C. Y., Chen, C. H., Yan, S. J. & Yoshioka, T., 12 1 2017, : : Scientific reports. 7, 1, 3606.

研究成果: ジャーナルへの寄稿記事

Oxidative stress
Disulfides
Hydrogen
Gases
Reactive Oxygen Species
1 引用 (Scopus)

Immunochromatographic determination of bacopaside I in biological samples

Sookying, S., Pekthong, D., Oo-puthinan, S., Phrompittayarat, W., Putalun, W., Tanaka, H., Xing, J., Zhan, Z., Khorana, N., Nuengchamnong, N. & Ingkaninan, K., 1 1 2017, : : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1040, p. 60-66 7 p.

研究成果: ジャーナルへの寄稿記事

Urine
Feces
Rats
Bacopa
Pharmacokinetics
5 引用 (Scopus)

Initiation of DNA replication at the chromosomal origin of E. coli, oriC

Katayama, T., 1 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 79-98 20 p. (Advances in Experimental Medicine and Biology; 巻数 1042).

研究成果: 著書/レポートタイプへの貢献

DNA Replication
Escherichia coli
Adenosine Triphosphate
DNA
Adenosine Diphosphate
26 引用 (Scopus)

Intracellular metabolite β-glucosylceramide is an endogenous Mincle ligand possessing immunostimulatory activity

Nagata, M., Izumi, Y., Ishikawa, E., Kiyotake, R., Doi, R., Iwai, S., Omahdi, Z., Yamaji, T., Miyamoto, T., Bamba, T. & Yamasaki, S., 4 18 2017, : : Proceedings of the National Academy of Sciences of the United States of America. 114, 16, p. E3285-E3294

研究成果: ジャーナルへの寄稿記事

Glucosylceramides
C-Type Lectins
Macrophages
Ligands
Dendritic Cells
12 引用 (Scopus)

Involvement of Organic Cation Transporters in the Kinetics of Trimethylamine N-oxide

Miyake, T., Mizuno, T., Mochizuki, T., Kimura, M., Matsuki, S., Irie, S., Ieiri, I., Maeda, K. & Kusuhara, H., 9 2017, : : Journal of Pharmaceutical Sciences. 106, 9, p. 2542-2550 9 p.

研究成果: ジャーナルへの寄稿記事

Cations
Kidney
trimethyloxamine
Tetraethylammonium
Tissue Distribution

Lipid radicals cause light-induced retinal degeneration

Enoki, M., Shinto, S., Matsuoka, Y., Otsuka, A., Kaidzu, S., Tanito, M., Shibata, T., Uchida, K., Ohira, A., Yamato, M. & Yamada, K-I., 9 20 2017, : : Chemical Communications.

研究成果: ジャーナルへの寄稿記事

Lipids
Animals
Imaging techniques
Molecules
5 引用 (Scopus)

Lipid radicals cause light-induced retinal degeneration

Enoki, M., Shinto, S., Matsuoka, Y., Otsuka, A., Kaidzu, S., Tanito, M., Shibata, T., Uchida, K., Ohira, A., Yamato, M. & Yamada, K-I., 1 1 2017, : : Chemical Communications. 53, 79, p. 10922-10925 4 p.

研究成果: ジャーナルへの寄稿記事

Lipids
Animals
Imaging techniques
Molecules
8 引用 (Scopus)

Lipophilic triphenylphosphonium derivatives enhance radiation-induced cell killing via inhibition of mitochondrial energy metabolism in tumor cells

Yasui, H., Yamamoto, K., Suzuki, M., Sakai, Y., Bo, T., Nagane, M., Nishimura, E., Yamamori, T., Inanami, O., Yamada, K-I. & Yamasaki, T., 4 1 2017, : : Cancer Letters. 390, p. 160-167 8 p.

研究成果: ジャーナルへの寄稿記事

Energy Metabolism
Radiation
Neoplasms
Adenosine Triphosphate
Cations
5 引用 (Scopus)

Lycocasuarines A–C, Lycopodium alkaloids from Lycopodiastrum casuarinoides

Wang, L. L., Zhou, Z. B., Zhu, X. L., Yuan, F. Y., Miyamoto, T. & Pan, K., 12 27 2017, : : Tetrahedron Letters. 58, 52, p. 4827-4831 5 p.

研究成果: ジャーナルへの寄稿記事

Lycopodium
Alkaloids
Dilatation and Curettage
Spectroscopic analysis
X ray crystallography
5 引用 (Scopus)

Mechano-sensitivity of mitochondrial function in mouse cardiac myocytes

Iribe, G., Kaihara, K., Yamaguchi, Y., Michio, N., Inoue, R. & Naruse, K., 11 1 2017, : : Progress in Biophysics and Molecular Biology. 130, p. 315-322 8 p.

研究成果: ジャーナルへの寄稿記事

Cardiac Myocytes
Reactive Oxygen Species
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone
Mitochondria
Organelles
3 引用 (Scopus)

Metabolomic profiling of brain tissues of mice chronically exposed to heroin

Li, R. S., Takeda, T., Ohshima, T., Yamada, H. & Ishii, Y., 2 2017, : : Drug Metabolism and Pharmacokinetics. 32, 1, p. 108-111 4 p.

研究成果: ジャーナルへの寄稿記事

Metabolomics
Heroin
Brain
Melatonin
Catecholamines

Microglia and its phagocytic abilities.

Noda, M., 2017, : : Clinical Pathophysiology. 23, 1, p. 11-18 8 p., 22(1).

研究成果: ジャーナルへの寄稿評論記事

Microglia
Phagocytosis
Ficus
Cytophagocytosis
Nerve Tissue
16 引用 (Scopus)

MiR30-GALNT1/2 axis-mediated glycosylation contributes to the increased secretion of inactive human prohormone for brain natriuretic peptide (proBNP) from failing hearts

Nakagawa, Y., Nishikimi, T., Kuwahara, K., Fujishima, A., Oka, S., Tsutamoto, T., Kinoshita, H., Nakao, K., Cho, K., Inazumi, H., Okamoto, H., Nishida, M., Kato, T., Fukushima, H., Yamashita, J. K., Wijnen, W. J., Creemers, E. E., Kangawa, K., Minamino, N., Nakao, K. および1人, Kimura, T., 1 1 2017, : : Journal of the American Heart Association. 6, 2, e003601.

研究成果: ジャーナルへの寄稿記事

Brain Natriuretic Peptide
Glycosylation
Heart Failure
MicroRNAs
Cyclic GMP
8 引用 (Scopus)

Mitotic slippage and the subsequent cell fates after inhibition of Aurora B during tubulin-binding agent-induced mitotic arrest

Tsuda, Y., Iimori, M., Nakashima, Y., Nakanishi, R., Ando, K., Ohgaki, K., Kitao, H., Saeki, H., Oki, E. & Maehara, Y., 12 1 2017, : : Scientific reports. 7, 1, 16762.

研究成果: ジャーナルへの寄稿記事

Tubulin
Microtubules
eribulin
Aurora Kinase B
Endoreduplication
2 引用 (Scopus)

Molecular mechanism for chromatin regulation during MCM loading in mammalian cells

Sugimoto, N. & Fujita, M., 1 1 2017, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 61-78 18 p. (Advances in Experimental Medicine and Biology; 巻数 1042).

研究成果: 著書/レポートタイプへの貢献

Multicarrier modulation
Chromatin
Nucleosomes
Licensure
Cells
1 引用 (Scopus)

Molecular mechanism whereby maternal exposure to dioxin suppresses sexual maturation of the offspring after growing up

Takeda, T., 1 1 2017, : : Yakugaku Zasshi. 137, 11, p. 1373-1379 7 p.

研究成果: ジャーナルへの寄稿評論記事

Maternal Exposure
Sexual Maturation
Dioxins
Luteinizing Hormone
Histone Deacetylases