研究成果 1976 2020

2017
1 引用 (Scopus)

Monitoring trifluridine incorporation in the peripheral blood mononuclear cells of colorectal cancer patients under trifluridine/tipiracil medication

Nakanishi, R., Kitao, H., Kiniwa, M., Morodomi, Y., Iimori, M., Kurashige, J., Sugiyama, M., Nakashima, Y., Saeki, H., Oki, E. & Maehara, Y., 12 1 2017, : : Scientific reports. 7, 1, 16969.

研究成果: ジャーナルへの寄稿記事

Trifluridine
Colorectal Neoplasms
Blood Cells
Antibodies
DNA
10 引用 (Scopus)

Mouse D-amino-acid oxidase: Distribution and physiological substrates

Koga, R., Miyoshi, Y., Sakaue, H., Hamase, K. & Konno, R., 12 4 2017, : : Frontiers in Molecular Biosciences. 4, DEC, 82.

研究成果: ジャーナルへの寄稿評論記事

D-Amino-Acid Oxidase
Substrates
Serine
Amino Acids
Alanine
3 引用 (Scopus)

Neuritogenic and neuroprotective constituents from Aquilaria crassna leaves

Supasuteekul, C., Tadtong, S., Putalun, W., Tanaka, H., Likhitwitayawuid, K., Tengamnuay, P. & Sritularak, B., 6 2017, : : Journal of Food Biochemistry. 41, 3, e12365.

研究成果: ジャーナルへの寄稿記事

Thymelaeaceae
neuroprotective effect
Neurons
leaves
Antipyretics
37 引用 (Scopus)

Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex

Makoto, T., Koga, K., Chen, T. & Zhuo, M., 5 1 2017, : : Journal of Neurochemistry. 141, 4, p. 486-498 13 p.

研究成果: ジャーナルへの寄稿評論記事

Gyrus Cinguli
Neurology
Neuralgia
Chronic Pain
Pain
9 引用 (Scopus)

Nicotine inhibits activation of microglial proton currents via interactions with α7 acetylcholine receptors

Noda, M. & Kobayashi, A., 1 1 2017, : : Journal of Physiological Sciences. 67, 1, p. 235-245 11 p.

研究成果: ジャーナルへの寄稿記事

Microglia
Cholinergic Receptors
Nicotine
Protons
Nicotinic Receptors
8 引用 (Scopus)
Electron Spin Resonance Spectroscopy
Oxidation-Reduction
Glutathione
Paramagnetic resonance
Brain
3 引用 (Scopus)

Oleanane-type glycosides from Pittosporum tenuifolium “variegatum” and P. tenuifolium “gold star”

Rengifo Carrillo, M., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Pouységu, L., Quideau, S., Rosquete Porcar, C. & Lacaille-Dubois, M. A., 8 1 2017, : : Phytochemistry. 140, p. 166-173 8 p.

研究成果: ジャーナルへの寄稿記事

Rosales
Glycosides
Gold
gold
Stars
26 引用 (Scopus)

P2 receptors, microglial cytokines and chemokines, and neuropathic pain

Makoto, T., 6 1 2017, : : Journal of Neuroscience Research. 95, 6, p. 1319-1329 11 p.

研究成果: ジャーナルへの寄稿評論記事

Cytokine Receptors
Chemokine Receptors
Neuralgia
Microglia
Peripheral Nerve Injuries
4 引用 (Scopus)
NFATC Transcription Factors
Cell signaling
CC Chemokines
Microglia
Adenosine Diphosphate
5 引用 (Scopus)

Periodic variation in bile acids controls circadian changes in uric acid via regulation of xanthine oxidase by the orphan nuclear receptor PPARα

Kanemitsu, T., Tsurudome, Y., Kusunose, N., Oda, M., Matsunaga, N., Koyanagi, S. & Ohdo, S., 1 1 2017, : : Journal of Biological Chemistry. 292, 52, p. 21397-21406 10 p.

研究成果: ジャーナルへの寄稿記事

Orphan Nuclear Receptors
Peroxisome Proliferator-Activated Receptors
Xanthine Oxidase
Uric Acid
Bile Acids and Salts
5 引用 (Scopus)

Peripheral membrane interactions boost the engagement by an anti-HIV-1 broadly neutralizing antibody

Rujas, E., Caaveiro, J. M. M., Insausti, S., García-Porras, M., Tsumoto, K. & Nieva, J. L., 3 31 2017, : : Journal of Biological Chemistry. 292, 13, p. 5571-5583 13 p.

研究成果: ジャーナルへの寄稿記事

Neutralizing Antibodies
HIV-1
Membranes
Antibodies
Epitopes
7 引用 (Scopus)
Calcineurin
Type C Phospholipases
Osteoclasts
Bone
Up-Regulation
2 引用 (Scopus)

Possible function of the second RecJ-like protein in stalled replication fork repair by interacting with Hef

Nagata, M., Ishino, S., Yamagami, T., Simons, J. R., Kanai, T., Atomi, H. & Ishino, Y., 12 1 2017, : : Scientific reports. 7, 1, 16949.

研究成果: ジャーナルへの寄稿記事

Thermococcus
Proteins
Exonucleases
Archaea
DNA Repair

Preface to heterocycles issue honoring the 70th birthday of professor Masakatsu Shibasaki

Ohshima, T., 1 1 2017, : : Heterocycles. 95, 1, p. 3-6 4 p.

研究成果: ジャーナルへの寄稿編集

6 引用 (Scopus)

Purinergic P2Y6 receptors: A new therapeutic target of age-dependent hypertension

Sunggip, C., Nishimura, A., Shimoda, K., Numaga-Tomita, T., Makoto, T. & Nishida, M., 6 1 2017, : : Pharmacological Research. 120, p. 51-59 9 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic Receptors
Hypertension
Angiotensin Type 1 Receptor
clopidogrel
Purinergic P2Y12 Receptors
18 引用 (Scopus)

Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases

Nishimura, A., Sunggip, C., Oda, S., Numaga-Tomita, T., Makoto, T. & Nishida, M., 12 1 2017, : : Pharmacology and Therapeutics. 180, p. 113-128 16 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2Y Receptors
G-Protein-Coupled Receptors
Cardiovascular System
Cardiovascular Diseases
Uracil Nucleotides

Purinergic signaling in cardiovascular system

Nishimura, A. & Nishida, M., 1 1 2017, : : Folia Pharmacologica Japonica. 149, 2, p. 84-90 7 p.

研究成果: ジャーナルへの寄稿記事

Uracil
Cardiovascular System
Adenosine
Signal Transduction
Hypertension
7 引用 (Scopus)

Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells

Nishida, M., Nishimura, A., Matsunaga, T., Motohashi, H., Kasamatsu, S. & Akaike, T., 8 2017, : : Free Radical Biology and Medicine. 109, p. 132-140 9 p.

研究成果: ジャーナルへの寄稿評論記事

Metabolism
Oxidation-Reduction
Nitric Oxide
Cardiovascular Physiological Phenomena
Cell signaling
15 引用 (Scopus)

Regulatory dynamics in the ternary DnaA complex for initiation of chromosomal replication in Escherichia coli

Sakiyama, Y., Kasho, K., Noguchi, Y., Kawakami, H. & Katayama, T., 12 1 2017, : : Nucleic acids research. 45, 21, p. 12354-12373 20 p.

研究成果: ジャーナルへの寄稿記事

Adenosine Triphosphate
Escherichia coli
Binding Sites
Protein Subunits
Replication Origin
38 引用 (Scopus)

Reversible ratiometric detection of highly reactive hydropersulfides using a FRET-based dual emission fluorescent probe

Kawagoe, R., Takashima, I., Uchinomiya, S. & Ojida, A., 1 1 2017, : : Chemical Science. 8, 2, p. 1134-1140 7 p.

研究成果: ジャーナルへの寄稿記事

Fluorescent Dyes
Pyronine
Cells
Cell signaling
Mammals

Role of vasopressin V1a receptor in ∆9-tetrahydrocannabinol-induced cataleptic immobilization in mice

Egashira, N., Koushi, E., Myose, T., Tanoue, A., Mishima, K., Tsuchihashi, R., Kinjo, J., Tanaka, H., Morimoto, S. & Iwasaki, K., 12 1 2017, : : Psychopharmacology. 234, 23-24, p. 3475-3483 9 p.

研究成果: ジャーナルへの寄稿記事

Catalepsy
Vasopressin Receptors
Dronabinol
Immobilization
Knockout Mice

Roles and educational effects of clinical case studies in home medical care

Ohsawa, T. & Shimazoe, T., 1 1 2017, : : Yakugaku Zasshi. 137, 8, p. 947-956 10 p.

研究成果: ジャーナルへの寄稿評論記事

Home Care Services
Pharmacists
Students
Education
Diagnostic Self Evaluation
8 引用 (Scopus)

Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes

Yoshimatsu, Y., Nakahara, T., Tanaka, K., Inagawa, Y., Narisawa-Saito, M., Yugawa, T., Ohno, S. I., Fujita, M., Nakagama, H. & Kiyono, T., 7 2017, : : Cancer Science. 108, 7, p. 1303-1309 7 p.

研究成果: ジャーナルへの寄稿記事

PDZ Domains
Keratinocytes
Neoplastic Cell Transformation
Carcinogenesis
Proteins
9 引用 (Scopus)

Self-Assembly Behavior of Emissive Urea Benzene Derivatives Enables Heat-Induced Accumulation in Tumor Tissue

Araki, T., Murayama, S., Usui, K., Shimada, T., Aoki, I. & Karasawa, S., 4 12 2017, : : Nano Letters. 17, 4, p. 2397-2403 7 p.

研究成果: ジャーナルへの寄稿記事

Benzene Derivatives
ureas
Urea
Self assembly
self assembly
19 引用 (Scopus)

Small-Dosing Clinical Study: Pharmacokinetic, Pharmacogenomic (SLCO2B1 and ABCG2), and Interaction (Atorvastatin and Grapefruit Juice) Profiles of 5 Probes for OATP2B1 and BCRP

Kashihara, Y., Ieiri, I., Yoshikado, T., Maeda, K., Fukae, M., Kimura, M., Hirota, T., Matsuki, S., Irie, S., Izumi, N., Kusuhara, H. & Sugiyama, Y., 9 2017, : : Journal of Pharmaceutical Sciences. 106, 9, p. 2688-2694 7 p.

研究成果: ジャーナルへの寄稿記事

Citrus paradisi
Pharmacogenetics
Pharmacokinetics
Sulfasalazine
Pharmaceutical Preparations
9 引用 (Scopus)

Sodium periodate-mediated conjugation of harringtonine enabling the production of a highly specific monoclonal antibody, and the development of a sensitive quantitative analysis method

Sakamoto, S., Yusakul, G., Tsuneura, Y., Putalun, W., Usui, K., Miyamoto, T., Tanaka, H. & Morimoto, S., 4 7 2017, : : Analyst. 142, 7, p. 1140-1148 9 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal antibodies
quantitative analysis
antibody
Monoclonal Antibodies
Sodium
Leukemia
Derivatives
Cephalotaxus
Immunosorbents
Acute Promyelocytic Leukemia

Species-dependent difference in the circadian rhythms of drug pharmacokinetics

Koyanagi, S. & Ohdo, S., 1 1 2017, : : Drug Delivery System. 32, 5, p. 418-423 6 p.

研究成果: ジャーナルへの寄稿記事

Circadian Rhythm
Pharmacokinetics
Circadian Clocks
Pharmaceutical Preparations
Rodentia
1 引用 (Scopus)

Specific activation of inhibitory interneurons in the spinal dorsal horn suppresses repetitive scratching in mouse models of chronic itch

Kanehisa, K., Shiratori-Hayashi, M., Koga, K., Tozaki-Saitoh, H., Kohro, Y., Takamori, K. & Tsuda, M., 11 2017, : : Journal of Dermatological Science. 88, 2, p. 251-254 4 p.

研究成果: ジャーナルへの寄稿レター

Cyclopropanes
Muscarinic M3 Receptors
Genetic engineering
Clozapine
Animals
3 引用 (Scopus)

Spinal dorsal horn astrocytes: New players in chronic itch

Tsuda, M., 1 1 2017, : : Allergology International. 66, 1, p. 31-35 5 p.

研究成果: ジャーナルへの寄稿評論記事

Atopic Dermatitis
Astrocytes
Skin
Spinal Cord Dorsal Horn
Therapeutics
20 引用 (Scopus)

Stimulation of adenosine A2B receptor inhibits endothelin-1-induced cardiac Fibroblast proliferation and α-smooth muscle actin synthesis through the cAMP/Epac/PI3K/Akt-signaling pathway

Phosri, S., Arieyawong, A., Bunrukchai, K., Parichatikanond, W., Nishimura, A., Nishida, M. & Mangmool, S., 6 30 2017, : : Frontiers in Pharmacology. 8, JUN, 428.

研究成果: ジャーナルへの寄稿記事

Endothelin A Receptors
Phosphatidylinositol 3-Kinases
Adenosine
Endothelin-1
Smooth Muscle
6 引用 (Scopus)

Strongly Chemiluminescent Acridinium Esters under Neutral Conditions: Synthesis, Properties, Determination, and Theoretical Study

Nakazono, M., Oshikawa, Y., Nakamura, M., Kubota, H. & Nanbu, S., 3 3 2017, : : Journal of Organic Chemistry. 82, 5, p. 2450-2461 12 p.

研究成果: ジャーナルへの寄稿記事

Acridines
Chemiluminescence
Esters
Salts
Hydrogen Peroxide
2 引用 (Scopus)

Structural analysis of oleanane-type saponins from the roots of Wisteria frutescens

Champy, A. S., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Papini, A. M. & Lacaille-Dubois, M. A., 6 1 2017, : : Magnetic Resonance in Chemistry. 55, 6, p. 595-600 6 p.

研究成果: ジャーナルへの寄稿レター

Wisteria
Magnetic resonance spectroscopy
Oleanolic Acid
Molecular Conformation
Plant Roots
3 引用 (Scopus)

Structural analysis of the histamine H1 receptor

Shiroishi, M. & Kobayashi, T., 1 1 2017, Handbook of Experimental Pharmacology. Springer New York LLC, p. 21-30 10 p. (Handbook of Experimental Pharmacology; 巻数 241).

研究成果: 著書/レポートタイプへの貢献

Doxepin
Histamine H1 Receptors
Histamine Antagonists
Structural analysis
Anions
6 引用 (Scopus)

Synchronized Chiral Induction between [5]Helicene–Spermine Ligand and B–Z DNA Transition

Kawara, K., Tsuji, G., Taniguchi, Y. & Sasaki, S., 1 1 2017, : : Chemistry - A European Journal. 23, 8, p. 1763-1769 7 p.

研究成果: ジャーナルへの寄稿記事

Chirality
DNA
Ligands
Z-Form DNA
B-Form DNA

Synthesis of 1-tetrasubstituted 2,2,2-trifluoroethylamine derivatives via palladium-catalyzed allylation of sp3 C–H bonds

Morisaki, K., Kondo, Y., Sawa, M., Morimoto, H. & Ohshima, T., 1 1 2017, : : Chemical and Pharmaceutical Bulletin. 65, 11, p. 1089-1092 4 p.

研究成果: ジャーナルへの寄稿記事

Allylation
Palladium
Derivatives
Carbon
Imines
2 引用 (Scopus)

Synthesis of polyunsaturated fatty acid-containing glucuronosyl-diacylglycerol through direct glycosylation

Wang, Q., Kuramoto, Y., Okazaki, Y., Ota, E., Morita, M., Hirai, G., Saito, K. & Sodeoka, M., 1 1 2017, : : Tetrahedron Letters. 58, 30, p. 2915-2918 4 p.

研究成果: ジャーナルへの寄稿記事

Glycosylation
Glycerides
Glycolipids
Glucuronides
Unsaturated Fatty Acids
5 引用 (Scopus)

Synthesis of the Right‐Side Structure of Type B Physalins

Morita, M., Kojima, S., Ohkubo, M., Koshino, H., Hashizume, D., Hirai, G., Maruoka, K. & Sodeoka, M., 2017, : : Israel Journal of Chemistry. 57, 3-4, p. 309-318 10 p.

研究成果: ジャーナルへの寄稿記事

Methylation
Kinetics
physalin B

Tetranuclear zinc cluster-catalyzed transesterification

Ohshima, T., 1 1 2017, New Horizons of Process Chemistry: Scalable Reactions and Technologies. Springer Singapore, p. 65-87 23 p.

研究成果: 著書/レポートタイプへの貢献

transesterification
Transesterification
Zinc
zinc
catalysts
14 引用 (Scopus)

The activation of SRC family kinases and focal adhesion kinase with the loss of the amplified, mutated EGFR gene contributes to the resistance to afatinib, erlotinib and osimertinib in human lung cancer cells

Murakami, Y., Sonoda, K., Abe, H., Watari, K., Kusakabe, D., Azuma, K., Kawahara, A., Akiba, J., Oneyama, C., Pachter, J. A., Sakai, K., Nishio, K., Kuwano, M. & Ono, M., 1 1 2017, : : Oncotarget. 8, 41, p. 70736-70751 16 p.

研究成果: ジャーナルへの寄稿記事

erbB-1 Genes
Focal Adhesion Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor
Lung Neoplasms
Phosphotransferases
8 引用 (Scopus)

The Cdc45/RecJ-like protein forms a complex with GINS and MCM, and is important for DNA replication in Thermococcus kodakarensis

Nagata, M., Ishino, S., Yamagami, T., Ogino, H., Simons, J. R., Kanai, T., Atomi, H. & Ishino, Y., 10 1 2017, : : Nucleic acids research. 45, 18, p. 10693-10705 13 p.

研究成果: ジャーナルへの寄稿記事

Thermococcus
DNA Replication
Maintenance
Proteins
DNA Helicases

The current status of nursing professionalism among nursing faculty in Japan

Tanaka, M., Taketomi, K., Yonemitsu, Y. & Kawamoto, R., 1 1 2017, : : Journal of Nursing Research. 25, 1, p. 7-12 6 p.

研究成果: ジャーナルへの寄稿記事

Nursing Faculties
Japan
Nursing
Nursing Education
Equipment and Supplies
20 引用 (Scopus)

The DnaA cycle in Escherichia coli: Activation, function and inactivation of the initiator protein

Katayama, T., Kasho, K. & Kawakami, H., 12 21 2017, : : Frontiers in Microbiology. 8, DEC, 2496.

研究成果: ジャーナルへの寄稿評論記事

Adenosine Triphosphate
Integration Host Factors
Escherichia coli
Adenosine Diphosphate
Proteins
4 引用 (Scopus)

The effect of varying the peptide linker length in a single chain variable fragment antibody against wogonin glucuronide

Paudel, M. K., Sakamoto, S., Van Huy, L., Tanaka, H., Miyamoto, T. & Morimoto, S., 6 10 2017, : : Journal of Biotechnology. 251, p. 47-52 6 p.

研究成果: ジャーナルへの寄稿記事

Single-Chain Antibodies
Glucuronides
Antibodies
Peptides
Assays
5 引用 (Scopus)

The proton-sensing G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) shows cardioprotective effects against myocardial infarction

Nagasaka, A., Mogi, C., Ono, H., Nishi, T., Horii, Y., Ohba, Y., Sato, K., Michio, N., Okajima, F. & Kurose, H., 12 1 2017, : : Scientific reports. 7, 1, 7812.

研究成果: ジャーナルへの寄稿記事

G-Protein-Coupled Receptors
Protons
Cell Death
Myocardial Infarction
T-Lymphocytes
2 引用 (Scopus)

The structure of an archaeal β-glucosaminidase provides insight into glycoside hydrolase evolution

Mine, S., Watanabe, M., Kamachi, S., Abe, Y. & Ueda, T., 3 24 2017, : : Journal of Biological Chemistry. 292, 12, p. 4996-5006 11 p.

研究成果: ジャーナルへの寄稿記事

Hexosaminidases
Glycoside Hydrolases
Galactosidases
Glucosamine
Catalytic Domain

The study of DDS on the basis of circadian clock system

Naoya, M., 1 1 2017, : : Drug Delivery System. 32, 1, p. 72-73 2 p.

研究成果: ジャーナルへの寄稿コメント/討論

Circadian Clocks
5 引用 (Scopus)

TRF2 recruits ORC through TRFH domain dimerization

Higa, M., Kushiyama, T., Kurashige, S., Kohmon, D., Enokitani, K., Iwahori, S., Sugimoto, N., Yoshida, K. & Fujita, M., 1 1 2017, : : Biochimica et Biophysica Acta - Molecular Cell Research. 1864, 1, p. 191-201 11 p.

研究成果: ジャーナルへの寄稿記事

Origin Recognition Complex
Dimerization
Telomere
DNA Replication
Chromatin
8 引用 (Scopus)

TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy

Shimauchi, T., Numaga-Tomita, T., Ito, T., Nishimura, A., Matsukane, R., Oda, S., Hoka, S., Ide, T., Koitabashi, N., Uchida, K., Sumimoto, H., Mori, Y. & Nishida, M., 8 3 2017, : : JCI Insight. 2, 15

研究成果: ジャーナルへの寄稿記事

公開
NADPH Oxidase
Doxorubicin
Atrophy
Cardiac Myocytes
Compliance
3 引用 (Scopus)

TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice

Oda, S., Numaga-Tomita, T., Kitajima, N., Toyama, T., Harada, E., Shimauchi, T., Nishimura, A., Ishikawa, T., Kumagai, Y., Birnbaumer, L. & Nishida, M., 12 1 2017, : : Scientific reports. 7, 1, 7511.

研究成果: ジャーナルへの寄稿記事

NADPH Oxidase
Hyperglycemia
Heart Failure
Proteins
Reactive Oxygen Species