研究成果 1976 2019

フィルター
評論記事
2019

Chronopharmacological strategies focused on chrono-drug discovery

Ohdo, S., Satoru, K. & Naoya, M., 10 1 2019, : : Pharmacology and Therapeutics. 202, p. 72-90 19 p.

研究成果: ジャーナルへの寄稿評論記事

Drug Discovery
Periodicity
Chronic Renal Insufficiency
Pharmaceutical Preparations
Neoplastic Stem Cells
1 引用 (Scopus)

Circulating messenger for neuroprotection induced by molecular hydrogen

Noda, M., Uemura, Y., Yoshii, Y., Horita, T., Takemi, S., Sakata, I. & Sakai, T., 1 1 2019, : : Canadian Journal of Physiology and Pharmacology. 97, 10, p. 909-915 7 p.

研究成果: ジャーナルへの寄稿評論記事

Ghrelin
Hydrogen
Drinking Water
Oxidative Stress
Ghrelin Receptor
4 引用 (Scopus)

Clinical Pharmacokinetics of Anaplastic Lymphoma Kinase Inhibitors in Non-Small-Cell Lung Cancer

Hirota, T., Muraki, S. & Ieiri, I., 4 4 2019, : : Clinical Pharmacokinetics. 58, 4, p. 403-420 18 p.

研究成果: ジャーナルへの寄稿評論記事

Non-Small Cell Lung Carcinoma
Pharmacokinetics
Pharmaceutical Preparations
Cytochrome P-450 Enzyme System
Cytochrome P-450 CYP3A

Development of novel functional molecules targeting DNA and RNA

Sasaki, S., 1 1 2019, : : Chemical and Pharmaceutical Bulletin. 67, 6, p. 505-518 14 p.

研究成果: ジャーナルへの寄稿評論記事

公開
Nucleosides
Oligonucleotides
Artificial Receptors
RNA
Molecules
1 引用 (Scopus)

Marine natural products from Indonesian waters

Hanif, N., Murni, A., Tanaka, C. & Tanaka, J., 6 19 2019, : : Marine Drugs. 17, 6, 364.

研究成果: ジャーナルへの寄稿評論記事

公開
Biological Products
Biodiversity
Water
Organic Chemistry
Aquatic Organisms
1 引用 (Scopus)

Metabolic plasticity of astrocytes and aging of the brain

Morita, M., Ikeshima-Kataoka, H., Kreft, M., Vardjan, N., Zorec, R. & Noda, M., 2 2 2019, : : International journal of molecular sciences. 20, 4, 941.

研究成果: ジャーナルへの寄稿評論記事

公開
plastic properties
Astrocytes
brain
Plasticity
Brain

Microglia-neuron interactions in the models of neuropathic pain

Saitoh, H. & Makoto, T., 11 1 2019, : : Biochemical Pharmacology. 169, 113614.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Neurons
Chronic Pain
Chemical activation
1 引用 (Scopus)

Mitochondrial dynamics in exercise physiology

Tanaka, T., Nishimura, A., Nishiyama, K., Goto, T., Numaga-Tomita, T. & Nishida, M., 1 1 2019, : : Pflugers Archiv European Journal of Physiology.

研究成果: ジャーナルへの寄稿評論記事

Mitochondrial Dynamics
Physiology
Organelle Biogenesis
Post Translational Protein Processing
Homeostasis

New applications of high-resolution analytical methods to study trace organic compounds in extraterrestrial materials

Naraoka, H., Hashiguchi, M., Sato, Y. & Hamase, K., 9 1 2019, : : Life. 9, 3, 62.

研究成果: ジャーナルへの寄稿評論記事

公開
Meteoroids
organic compounds
Organic compounds
analytical methods
organic compound
3 引用 (Scopus)

Oncogenic Y-box binding protein-1 as an effective therapeutic target in drug-resistant cancer

Kuwano, M., Shibata, T., Watari, K. & Ono, M., 5 2019, : : Cancer Science. 110, 5, p. 1536-1543 8 p.

研究成果: ジャーナルへの寄稿評論記事

公開
Y-Box-Binding Protein 1
Drug Resistance
Pharmaceutical Preparations
Neoplasms
Therapeutics

Recent strategic advances for the activation of benzylic C–H bonds for the formation of C–C bonds

Yazaki, R. & Ohshima, T., 11 7 2019, : : Tetrahedron Letters. 60, 45, 151225.

研究成果: ジャーナルへの寄稿評論記事

Hydrocarbons
Anions
Chemical activation
Feedstocks
2 引用 (Scopus)

TRPC channels in exercise-mimetic therapy

Numaga-Tomita, T., Oda, S., Nishiyama, K., Tanaka, T., Nishimura, A. & Nishida, M., 3 7 2019, : : Pflugers Archiv European Journal of Physiology. 471, 3, p. 507-517 11 p.

研究成果: ジャーナルへの寄稿評論記事

Exercise Therapy
Muscle
Mechanical Stress
Proteins
Oxidative stress
2018
6 引用 (Scopus)

Astrocytes in the spinal dorsal horn and chronic itch

Makoto, T., 1 1 2018, : : Neuroscience Research. 126, p. 9-14 6 p.

研究成果: ジャーナルへの寄稿評論記事

Atopic Dermatitis
Astrocytes
Peripheral Nervous System
Central Nervous System
Skin
1 引用 (Scopus)

Biophysical analysis of the protein-small molecule interactions to develop small molecule drug discovery

Nagatoishi, S., Martinez Caaveiro, J. M. & Tsumoto, K., 1 1 2018, : : Yakugaku Zasshi. 138, 8, p. 1033-1041 9 p.

研究成果: ジャーナルへの寄稿評論記事

Drug Discovery
Small Molecule Libraries
Thermodynamics
Proteins
Research Personnel
6 引用 (Scopus)

D-Amino acids in molecular evolution in space – Absolute asymmetric photolysis and synthesis of amino acids by circularly polarized light

Sugahara, H., Meinert, C., Nahon, L., Jones, N. C., Hoffmann, S. V., Hamase, K., Takano, Y. & Meierhenrich, U. J., 7 1 2018, : : Biochimica et Biophysica Acta - Proteins and Proteomics. 1866, 7, p. 743-758 16 p.

研究成果: ジャーナルへの寄稿評論記事

Molecular Evolution
Photolysis
Light polarization
Light
Amino Acids
9 引用 (Scopus)

DNA replication stress and cancer chemotherapy

Kitao, H., Iimori, M., Kataoka, Y., Wakasa, T., Tokunaga, E., Saeki, H., Oki, E. & Maehara, Y., 2 1 2018, : : Cancer Science. 109, 2, p. 264-271 8 p.

研究成果: ジャーナルへの寄稿評論記事

DNA Replication
Drug Therapy
Neoplasms
Biological Phenomena
Genomic Instability
21 引用 (Scopus)

Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites

Sakamoto, S., Putalun, W., Vimolmangkang, S., Phoolcharoen, W., Shoyama, Y., Tanaka, H. & Morimoto, S., 1 1 2018, : : Journal of Natural Medicines. 72, 1, p. 32-42 11 p.

研究成果: ジャーナルへの寄稿評論記事

Immunosorbents
Metabolites
Immunoassay
Assays
Enzyme-Linked Immunosorbent Assay

Epigenetic regulation of pharmacokinetic-related genes in human tissues

Hirota, T., 1 1 2018, : : Yakugaku Zasshi. 138, 11, p. 1391-1396 6 p.

研究成果: ジャーナルへの寄稿評論記事

Epigenomics
Pharmacokinetics
Breast Neoplasms
Pharmaceutical Preparations
Genes

Green Pharma: A new strategy for drug discovery in academia by targeting glial cells and ATP receptors

Yamashita, T., Makoto, T., Saitoh, H. & Inoue, K., 1 1 2018, : : Yakugaku Zasshi. 138, 8, p. 1027-1031 5 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Drug Discovery
Neuroglia
Hyperalgesia
Neuralgia
47 引用 (Scopus)

Microglia in neuropathic pain: Cellular and molecular mechanisms and therapeutic potential

Inoue, K. & Makoto, T., 2 16 2018, : : Nature Reviews Neuroscience. 19, 3, p. 138-152 15 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Chronic Pain
Nociceptive Pain
Peripheral Nerve Injuries
14 引用 (Scopus)

Modulation of Pain and Itch by Spinal Glia

Makoto, T., 2 1 2018, : : Neuroscience Bulletin. 34, 1, p. 178-185 8 p.

研究成果: ジャーナルへの寄稿評論記事

Neuroglia
Chronic Pain
Pain
Spinal Cord
Posterior Horn Cells
3 引用 (Scopus)

Therapeutic targets for treatment of heart failure: Focus on GRKs and β-arrestins affecting βaR signaling

Mangmool, S., Parichatikanond, W. & Kurose, H., 11 27 2018, : : Frontiers in Pharmacology. 9, NOV, 01336.

研究成果: ジャーナルへの寄稿評論記事

Arrestins
G-Protein-Coupled Receptor Kinases
Treatment Failure
Heart Failure
Adrenergic Receptors
13 引用 (Scopus)
Diacylglycerol Kinase
Phosphatidic Acids
Diglycerides
Phosphatidylinositols
Isoenzymes
2017
6 引用 (Scopus)

Activation of the FA pathway mediated by phosphorylation and ubiquitination

Ishiai, M., Sato, K., Tomida, J., Kitao, H., Kurumizaka, H. & Takata, M., 10 1 2017, : : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 803-805, p. 89-95 7 p.

研究成果: ジャーナルへの寄稿評論記事

Fanconi Anemia
Ubiquitination
Phosphorylation
Fanconi Anemia Complementation Group D2 Protein
Bone Marrow Cells
14 引用 (Scopus)

DNA replication origins and fork progression at mammalian telomeres

Higa, M., Fujita, M. & Yoshida, K., 4 2017, : : Genes. 8, 4, 112.

研究成果: ジャーナルへの寄稿評論記事

Replication Origin
Telomere
DNA Replication
Chromosomal Instability
Proteins
4 引用 (Scopus)

Epigenetic regulation of drug transporter expression in human tissues

Hirota, T., Tanaka, T., Takesue, H. & Ieiri, I., 1 2 2017, : : Expert Opinion on Drug Metabolism and Toxicology. 13, 1, p. 19-30 12 p.

研究成果: ジャーナルへの寄稿評論記事

Drug and Narcotic Control
Epigenomics
Tissue
Pharmaceutical Preparations
Genes
9 引用 (Scopus)

Fluorescence Sensing of Inorganic Phosphate and Pyrophosphate Using Small Molecular Sensors and Their Applications

Wongkongkatep, J., Ojida, A. & Hamachi, I., 4 1 2017, : : Topics in Current Chemistry. 375, 2, 30.

研究成果: ジャーナルへの寄稿評論記事

Fluorescence
Phosphates
Sensors
Chemical reactions
Quenching
9 引用 (Scopus)

Glycosylation of IgG-Fc: A molecular perspective

Kiyoshi, M., Tsumoto, K., Ishii-Watabe, A. & Martinez Caaveiro, J. M., 7 1 2017, : : International Immunology. 29, 7, p. 311-317 7 p.

研究成果: ジャーナルへの寄稿評論記事

Glycosylation
Polysaccharides
Immunoglobulin G
Antibodies
Immunoglobulin Isotypes
4 引用 (Scopus)

GRWD1, a new player among oncogenesis-related ribosomal/nucleolar proteins

Takafuji, T., Kayama, K., Sugimoto, N. & Fujita, M., 8 3 2017, : : Cell Cycle. 16, 15, p. 1397-1403 7 p.

研究成果: ジャーナルへの寄稿評論記事

Ribosomal Proteins
Nuclear Proteins
Carcinogenesis
Neoplasms
Protein Biosynthesis

Microglia and its phagocytic abilities.

Noda, M., 2017, : : Clinical Pathophysiology. 23, 1, p. 11-18 8 p., 22(1).

研究成果: ジャーナルへの寄稿評論記事

Microglia
Phagocytosis
Ficus
Cytophagocytosis
Nerve Tissue
1 引用 (Scopus)

Molecular mechanism whereby maternal exposure to dioxin suppresses sexual maturation of the offspring after growing up

Takeda, T., 1 1 2017, : : Yakugaku Zasshi. 137, 11, p. 1373-1379 7 p.

研究成果: ジャーナルへの寄稿評論記事

Maternal Exposure
Sexual Maturation
Dioxins
Luteinizing Hormone
Histone Deacetylases
10 引用 (Scopus)

Mouse D-amino-acid oxidase: Distribution and physiological substrates

Koga, R., Miyoshi, Y., Sakaue, H., Hamase, K. & Konno, R., 12 4 2017, : : Frontiers in Molecular Biosciences. 4, DEC, 82.

研究成果: ジャーナルへの寄稿評論記事

D-Amino-Acid Oxidase
Substrates
Serine
Amino Acids
Alanine
37 引用 (Scopus)

Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex

Makoto, T., Koga, K., Chen, T. & Zhuo, M., 5 1 2017, : : Journal of Neurochemistry. 141, 4, p. 486-498 13 p.

研究成果: ジャーナルへの寄稿評論記事

Gyrus Cinguli
Neurology
Neuralgia
Chronic Pain
Pain
26 引用 (Scopus)

P2 receptors, microglial cytokines and chemokines, and neuropathic pain

Makoto, T., 6 1 2017, : : Journal of Neuroscience Research. 95, 6, p. 1319-1329 11 p.

研究成果: ジャーナルへの寄稿評論記事

Cytokine Receptors
Chemokine Receptors
Neuralgia
Microglia
Peripheral Nerve Injuries
6 引用 (Scopus)

Purinergic P2Y6 receptors: A new therapeutic target of age-dependent hypertension

Sunggip, C., Nishimura, A., Shimoda, K., Numaga-Tomita, T., Makoto, T. & Nishida, M., 6 1 2017, : : Pharmacological Research. 120, p. 51-59 9 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic Receptors
Hypertension
Angiotensin Type 1 Receptor
clopidogrel
Purinergic P2Y12 Receptors
18 引用 (Scopus)

Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases

Nishimura, A., Sunggip, C., Oda, S., Numaga-Tomita, T., Makoto, T. & Nishida, M., 12 1 2017, : : Pharmacology and Therapeutics. 180, p. 113-128 16 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2Y Receptors
G-Protein-Coupled Receptors
Cardiovascular System
Cardiovascular Diseases
Uracil Nucleotides
6 引用 (Scopus)

Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells

Nishida, M., Nishimura, A., Matsunaga, T., Motohashi, H., Kasamatsu, S. & Akaike, T., 8 1 2017, : : Free Radical Biology and Medicine. 109, p. 132-140 9 p.

研究成果: ジャーナルへの寄稿評論記事

Metabolism
Oxidation-Reduction
Nitric Oxide
Cardiovascular Physiological Phenomena
Cell signaling

Roles and educational effects of clinical case studies in home medical care

Ohsawa, T. & Shimazoe, T., 1 1 2017, : : Yakugaku Zasshi. 137, 8, p. 947-956 10 p.

研究成果: ジャーナルへの寄稿評論記事

Home Care Services
Pharmacists
Students
Education
Diagnostic Self Evaluation
3 引用 (Scopus)

Spinal dorsal horn astrocytes: New players in chronic itch

Tsuda, M., 1 1 2017, : : Allergology International. 66, 1, p. 31-35 5 p.

研究成果: ジャーナルへの寄稿評論記事

Atopic Dermatitis
Astrocytes
Skin
Spinal Cord Dorsal Horn
Therapeutics
18 引用 (Scopus)

The DnaA cycle in Escherichia coli: Activation, function and inactivation of the initiator protein

Katayama, T., Kasho, K. & Kawakami, H., 12 21 2017, : : Frontiers in Microbiology. 8, DEC, 2496.

研究成果: ジャーナルへの寄稿評論記事

Adenosine Triphosphate
Integration Host Factors
Escherichia coli
Adenosine Diphosphate
Proteins
2016

Development of a functional contrast agent for targeting lipid-derived radicals

Yamada, K. I., 1 1 2016, : : Yakugaku Zasshi. 136, 8, p. 1093-1100 8 p.

研究成果: ジャーナルへの寄稿評論記事

Contrast Media
Lipids
Electrons
Oxidative Stress
Fluorescence

Development of fluorescence sensing mechanism for cell functional analysis

Ojida, A. & Takashima, I., 1 1 2016, : : Yakugaku Zasshi. 136, 1, p. 3-7 5 p.

研究成果: ジャーナルへの寄稿評論記事

Fluorescent Dyes
Fluorescence
Metals
Ions
Biological Phenomena
11 引用 (Scopus)
Zinc
Esters
Transesterification
Amines
Catalyst activity
10 引用 (Scopus)

Fluorescence probe for the convenient and sensitive detection of ascorbic acid

Matsuoka, Y., Yamato, M. & Yamada, K. I., 1 2016, : : Journal of Clinical Biochemistry and Nutrition. 58, 1, p. 16-22 7 p.

研究成果: ジャーナルへの寄稿評論記事

Ascorbic Acid
Fluorescence
Fluorescent Dyes
Oxidation-Reduction
Electrons
NADPH Oxidase
Nicotinic Receptors
Microglia
Nicotine
Protons

Memorial address for Dr. Hideyuki Yamada, distinguished professor

Ishii, Y., 10 1 2016, : : Drug Metabolism Reviews. 48, 4, p. 471-472 2 p.

研究成果: ジャーナルへの寄稿評論記事

17 引用 (Scopus)

Myofibroblasts and inflammatory cells as players of cardiac fibrosis

Kurose, H. & Mangmool, S., 8 1 2016, : : Archives of Pharmacal Research. 39, 8, p. 1100-1113 14 p.

研究成果: ジャーナルへの寄稿評論記事

Myofibroblasts
Fibrosis
Collagen
Fibroblasts
Cells
40 引用 (Scopus)

Neuron-microglia interaction by purinergic signaling in neuropathic pain following neurodegeneration

Tsuda, M. & Inoue, K., 5 1 2016, : : Neuropharmacology. 104, p. 76-81 6 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Neurons
Purinergic P2Y Receptors
Purinergic P2X Receptors

New mechanism for chronic itch in the nervous system

Makoto, T. & Shiratori, M., 1 1 2016, : : Seikagaku. 88, 5, p. 654-656 3 p.

研究成果: ジャーナルへの寄稿評論記事

Neurology
Animals
Astrocytes
Atopic Dermatitis