研究成果 1971 2020

フィルター
章 (査読済み)
2019

Evaluation of the binding ability of an orphan nuclear receptor nurr1 to synthetic peptides.

Masuya, T., Tada, Y., Liu, X. & Matsushima, A., 2019, Peptide Science 2018. p. 133

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

2018

Homodimer function of human nuclear receptor ERR evidenced using -helix peptides in the dimer interface

Liu, X., Nakagawa, H., Sugiyama, M., Matsushima, A., Shimohigashi, M. & Shimohigashi, Y., 2018, Peptide Science 2017. p. 190 191 p.

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Mutual co-work between nuclear receptor ERalpha and ERRgamma requires their homodimerization

Liu, X., Shimohigashi, M., Sugiyama, M., Matsushima, A. & Shimohigashi, Y., 2018, Peptide Science 2017,. p. 198 199 p.

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Phe 2715.39 of Thronbin Receptor PAR-1 is a specific target of Phe-2-phenl group of its tethered ligand

Sugiyama, M., Fujita, T., Liu, X., Matsuyama, Y., Matsushima, A., Shimohigashi, M. & Shimohigashi, Y., 2018, Peptide Science 2017. p. 94 95 p.

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

2017

Docking simulation to elucidate the labeled cysteine residue of the nociception receptor ORL1 using a Cys(Npys)-containing peptide ligand

Matsushima, A., Nishimura, H., Matsuyama, Y., Liu, X. & Shimohigashi, Y., 2017, Peptide Science 2016. p. 87-88

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

2016

Comparative analysis of the ligand binding domain secondary structures of human nuclear receptors

Matsuyama, Y., Nishimura, H., Liu, X., Matsushima, A. & Shimohigashi, Y., 2016, Peptide Science 2015. p. 337-338

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Comprehensive structural analysis of the nociceptin ORL1 receptor by means of virtual and experimental Ala-scanning combinated methods

Matsushima, A., Nishimura, H., Liu, X., Takesue, Y., Matsuyama, Y. & Shimohigashi, Y., 2016, Peptide Science 2015. p. 149-150

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Do the estrogen receptors function as a homodimer? experimental validation of homodimerization by inhibitory peptides

Sakito, S., Fujiyama, A., Motomatsu, Y., Liu, X., Matsushima, A. & Shimohigashi, Y., 2016, Peptide Science 2015. p. 335-336

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Do the estrogen receptors function as a homodimer? experimental validation of homodimerization by inhibitory peptides

Sakito, S., Liu, X., Fujiyama, A., Matsushima, A. & Shimohigashi, Y., 2016, Peptide Science 2015. p. 335-336

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Expression analysis of neuropeptide PDF mRNA in the hypoactive and hyperactive fruit flies Drosophila melanogaster

Asuka, T., Matsuo, A., Shotaro, U., Matsuyama, Y., masayuki, N., Sumiyoshi, M., Liu, X., Matsushima, A., Shimohigashi, M. & Shimohigashi, Y., 2016, Peptide Science 2015. p. 317-318

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Functional role of the Phe-Phe stacking microswitch in the ORL1 nociceptin receptor activation

Takesue, Y., Nishimura, H., Liu, X., Matsushima, A. & Shimohigashi, Y., 2016, Peptide Science 2015. p. 147-148

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

ORL1 Nociceptin receptor response of opioid peptides derived from proenkephalin precursor protein

Motomatsu, Y., Nishimura, H., Matsuyama, Y., Liu, X., Matsushima, A. & Shimohigashi, Y., 2016, Peptide Science 2015. p. 181-182

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

SCN Circadian rhythm signal transduction neuropeptides evoke hypoactive phenotype differently in male and female mice

Sugiyama, M., Motomatsu, Y., Matsuyama, Y., Kajiyama, S., Kameda, T., Uchimura, E., Saito, T., Liu, X., Matsushima, A. & Shimohigashi, Y., 2016, Peptide Science 2015. p. 53-54

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

2015

Alternative polyadenylation analyses of neuropeptide genes in bisphenol A-exposed hypoactive mouse brain

Sugiyama, M., Kajiyama, S., Saito, T., Uchimura, E., Motomatsu, Y., Matsuo, A., Matsushima, A. & Shimohigashi, Y., 2015, Peptide Science 2014. p. 345-346

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

An in silico genomic search of endomorphin-like opioid peptides

Matsushima, A., Koyanagi, K. O., Nishimura, H., Inamine, S., Motomatsu, Y. & Shimohigashi, Y., 2015, Peptide Science 2014. p. 281-282

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

A novel method identify and quantify the coactivator proteins that couple with human nuclear receptor: the use of interacting interface a-helix peptide for quantitative inhibition

Liu, X., Matsushima, A. & Shimohigashi, Y., 2015, Peptide Science 2014. p. 203-204

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Bisphenol A-induced substantial peak decay of Drosophila circadian neuropeptide hugin mRNA expression

Shotaro, U., Matsuo, A., Matsuyama, Y., Nakamura, M., Koga, K., Liu, X., Matsushima, A., Shimohigashi, M. & Shimohigashi, Y., 2015, Peptide Science 2014. p. 41-42

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

GPCR functional role of Phe-269 and Phe-221 in the molecular switching of ORL1 nociceptin receptor activation

Takesue, Y., Nishimura, H., Liu, X., Matsushima, A. & Shimohigashi, Y., 2015, Peptide Science 2014. p. 203-204

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Receptor selectivity and specificity of a series of opioid peptides latent in the proenkephalin precursor protein

Motomatsu, Y., Nishimura, H., Matsumoto, Y., Kuramitsu, Y., Inamine, S., Matsushima, A. & Shimohigashi, Y., 2015, Peptide Science 2014. p. 201-202

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Structural and molecular evolutionary analysis of the ligand-binding domain of forty-eight human nuclear receptors

Matsuyama, Y., Nishimura, H., Liu, X., Matsushima, A. & Shimohigashi, Y., 2015, Peptide Science 2014. p. 347-348

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Structure-activity Studies on the Halogenated Phe-containing Neuropeptide Substance P Analogs

Kuramitsu, Y., Nishimura, H., Nakamura, M., Suyama, K., Matsushima, A., Nose, T. & Shimohigashi, Y., 2015, Peptide Science 2014. p. 319-320

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

The molecular switching of ORL1 nociceptin receptor in activation/inactivation

Nishimura, H., Li, J., Isozaki, K., yuuki, T., Matsushima, A., Liu, X., Shimohigashi, M. & Shimohigashi, Y., 2015, Peptide Science 2014. p. 201-202

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

2014

Bisphenol A-induced Epigenetic Mutations in Circadian Pacemaker Neuropeptide mRNAs of Hyperactive Drosophila Fruit Flies

Matsuo, A., Umeno, S., Matsuyama, Y., Nakamura, M., Takeda, Y., Sumiyoshi, M., Liu, X., Matsushima, A., Shimohigashi, M. & Shimohigashi, Y., 2014, Peptide Science 2013. p. 457-458

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Constitutive α-Helix-peptides Required for Functional Dimerization of Estrogen-related Receptor γ (ERRγ).

Liu, X., Nishimura, H., Fujiyama, A., Matsushima, A. & Shimohigashi, Y., 2014, Peptide Science 2013. p. 429-430

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Expression and Mutation Analyses of Brain Neuropeptide Genes of Rndocrine-disrupting Bisphenol A-exposed Hypoactive Mouse

Sugiyama, M., Matsuo, A., Saito, T., Uchimura, E., Liu, X., Matsushima, A. & Shimohigashi, Y., 2014, Peptide Science 2013. p. 453-454

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Functionally Essential Amino Acid Residues in ORL1 Nociceptin Receptor for Ligand-stimulated Receptor Activation

Nishimura, H., Li, J., abe, Y., Isozaki, K., Matsushima, A., Inamine, S., Costa, T. & Shimohigashi, Y., 2014, Peptide Science 2013. p. 333-334

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Influence Analysis of the Circadian Evening Pacemaker Neuropeptide hugγ Gene in the Bisphenol A-exposed Fruit Fly Drosophila Brain

Umeno, S., Matsuo, A., Matsuyama, Y., Nakamura, M., Takeda, Y., Sumiyoshi, M., Liu, X., Matsushima, A. & Shimohigashi, Y., 2014, Peptide Science 2013. p. 455-456

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Multiple and Simultaneous Cys→Ala Mutations of ORL1 Nociceptin Receptor to Identify the Affinity Binding site of Cys(Npys)-Elongated RYYRIK Peptide Antagonist

Matsushima, A., Nishimura, H., Inamine, S. & Shimohigashi, Y., 2014, Peptide Science 2013. p. 413-414

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Specific Role of Phe Residues in Opioid Peptide Met-enkephalin- Arg-Phe in Binding to All Three Opioid Receptors

Motomatsu, Y., Nishimura, H., Matsumoto, Y., Inamine, S., Kuramitsu, Y., Matsushima, A. & Shimohigashi, Y., 2014, Peptide Science 2013. p. 317-318

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Structure-Activity Studies on the Halogenated Phe-containing Neuropeptide Substance P Analogs

Kuramitsu, Y., Nishimura, H., Nakamura, R., Suyama, K., Matsushima, A., Nose, T. & Shimohigashi, Y., 3 2014, Peptide Science 2013. p. 319-320 2 p.

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Three-dimensional Docking Modeling to Human Nuclear Receptors for Exploration of Bisphenol-A Targeting Receptors

Matsuyama, Y., Liu, X., Nishimura, H., Matsushima, A. & Shimohigashi, Y., 2014, Peptide Science 2013. p. 459-460

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

2013

Bisphenol-binding pocket of constitutively active nuclear receptor CAR: Docking modeling for close-packing

Matsuyama, Y., Liu, X., Nishimura, H., Matsushima, A., Nose, T. & Shimohigashi, Y., 2013, Peptide Science 2012. p. 401-402

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Exploration of pharmacological chaperone for rescue of misfolded and/or unfolded ORL1 nociceptin receptor proteins

Nishimura, H., Inamine, S., Li, J., Matsushima, A. & Shimohigashi, Y., 2013, Peptide Science 2012. p. 115-118

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Halogenated Phe-containing endomorphin-2 analogs with mixed agonist and antagonist activities

Nishio, K., Nishimura, H., Suyama, K., Matsushima, A., Nose, T. & Shimohigashi, Y., 2013, Peptide Science 2012. p. 25-26

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

High-precision binding assay procedure of tachykinin receptor NK-1 for highly potent Substance P analogs

Kuramitsu, Y., Nishimura, H., Nakamura, R., Suyama, K., Matsushima, A., Nose, T. & Shimohigashi, Y., 2013, Peptide Science 2012. p. 213-214

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Identification of affinity binding site of Cys(Npys)-elongated RYYRIK peptide antagonist by means of Cys→Ala mutated ORL1 nociceptin receptors

Matsushima, A., Nishimura, H., Inamine, S. & Shimohigashi, Y., 2013, Peptide Science 2012. p. 207-208

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Taxonomy of the genus Padina (Dictyotales, Phaeophyceae) based on morphological and molecular evidences, with key to species identification

Win, N. N., Hanyuda, T., Draisma, S. G. A., Lim, P-E., Phang, S-M. & Kawai, H., 2013, Taxonomy of Southeast Asian Seaweeds II. Phang, S-M. & Lim, P-E. (版). Kuala Lumpur: University of Malaya Press, p. 119 174 p. (Monograph Series 15).

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Dictyotales
Phaeophyceae
thallus
cations
taxonomy

The impact of bisphenol A-feeding on the Drosophila neuropeptide PDF mRNA structure

Matsuo, A., Nakamura, M., Takeda, Y., Matsuyama, Y., Sumiyoshi, M., Liu, X., Matsushima, A., Shimohigashi, M. & Shimohigashi, Y., 2013, Peptide Science 2012. p. 75-76

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Two different binding modes of peptide library-based antagonist acyl-RYYRIK amide in the orl1 nociceptin receptor

Inamine, S., Nishimura, H., Li, J., Matsushima, A., Costa, T. & Shimohigashi, Y., 2013, Peptide Science 2012. p. 229-230

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

2012

Affinity labeling of the ORL1 nociceptin receptor by Cys(Npys)-elongated RYYRIK peptide antagonist

Matsushima, A., Nishimura, H., Uemura, S., Li, J., Inamine, S. & Shimohigashi, Y., 2012, Peptide Science 2011. p. 179-180

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Application of denaturing gradient gel electrophoresis as an ecotoxicological tool to investigate the effects of aqui-fullerene on a bacterial community.

Hamamura, N., 2012, Interdisciplinary Studies on Environmental Chemistry. 巻 6. p. 79-88

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

公開

Effects of the halogenation of Phe-phenyl group of two consecutive residues in endomorphin-2 on the interaction with the μ–opioid receptors

Nishio, K., Nishimura, H., Suyama, K., Abe, Y., Matsushima, A., Nose, T. & Shimohigashi, Y., 2012, Peptide Science 2011. p. 171-172

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Identification of bacterial community and arsenate-reducing bacteria associated with a soda lake in Khovsgol, Mongolia.

Hamamura, N., 2012, Interdisciplinary Studies on Environmental Chemistry. 巻 6. p. 99-107

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

公開

Receptor Binding Characteristics of Tritium-labeled Pure antagonist Peptide for Hyperalgesic nociceptin ORL1 receptor

Inamine, S., Nishimura, H., Li, J., Matsushima, A., Nose, T., Costa, T. & Shimohigashi, Y., 2012, Peptide Science 2011. p. 183-184

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Structural Analysis of Delta Opioid Receptor Dimer by Bivalent Deltorphin II Analogs

Ito, N., Nishimura, H., Matsushima, A., Nose, T., Costa, T. & Shimohigashi, Y., 3 2012, Peptide Science 2011. p. 173-174 2 p.

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Structural Characteristics of Thr-Gly Dipeptide Repeat in the Drosophila Clock Protein PERIOD

Matsuo, A., Nishimura, H., Masayuki, N., Koga, K., Sumiyoshi, M., Matsushima, A., Nose, T., Shimohigashi, M. & Shimohigashi, Y., 3 2012, Peptide Science 2011. p. 351-352 2 p.

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

Structural Essentials of Hyperalgesic Nociceptin ORL1 Receptor for Ligand Binding and Receptor Activation

Nishimura, H., Li, J., Isozaki, K., Abe, Y., Inamine, S., Matsushima, A., Nose, T., Costa, T. & Shimohigashi, Y., 2012, Peptide Science 2011. p. 33-34

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

2011

Exploration of the binding site of ORL1 nociceptin receptor antagonist

Inamine, S., Nishimura, H., Matsushima, A., Nose, T., Costa, T. & Shimohigashi, Y., 2011, Peptide Science 2010. p. 167

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

New aspects of the coupling between thermosphere and ionosphere, with special regards to CHAMP mission results

Luehr, H., Liu, H. & Park, J., 2011, Aeronomy of the Earth's Atmosphere and Ionosphere. p. 303-316

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

QCM-analyses of the intermolecular interaction between prion protein N-terminal domains having increased number of octapeptide repeat.

Sato, K., Horiuchi, Y., Matsushima, A. & Shimohigashi, Y., 2011, Peptide Science 2010. p. 128

研究成果: 著書/レポートタイプへの貢献章 (査読済み)