口腔総合診療科

研究成果 1993 2019

2013
14 引用 (Scopus)

Exposure to transforming growth factor-β1 after basic fibroblast growth factor promotes the fibroblastic differentiation of human periodontal ligament stem/progenitor cell lines

Kono, K., Maeda, H., Fujii, S., Tomokiyo, A., Yamamoto, N., Wada, N., Monnouchi, S., Teramatsu, Y., Hamano, S., Koori, K. & Akamine, A., 5 1 2013, : : Cell and tissue research. 352, 2, p. 249-263 15 p.

研究成果: ジャーナルへの寄稿記事

Periodontal Ligament
Transforming Growth Factors
Fibroblast Growth Factor 2
Stem Cells
Cell Line
25 引用 (Scopus)

Immunohistochemical location of the p75 neurotrophin receptor (p75NTR) in oral leukoplakia and oral squamous cell carcinoma

Kiyosue, T., Kawano, S., Matsubara, R., Goto, Y., Hirano, M., Jinno, T., Toyoshima, T., Kitamura, R., Oobu, K. & Nakamura, S., 2 1 2013, : : International Journal of Clinical Oncology. 18, 1, p. 154-163 10 p.

研究成果: ジャーナルへの寄稿記事

Oral Leukoplakia
Nerve Growth Factor Receptor
Squamous Cell Carcinoma
Stem Cells
Keratin-5
40 引用 (Scopus)

Immunomodulatory effects of stem cells

Wada, N., Gronthos, S. & Bartold, P. M., 10 1 2013, : : Periodontology 2000. 63, 1, p. 198-216 19 p.

研究成果: ジャーナルへの寄稿記事

Mesenchymal Stromal Cells
Stem Cells
Periodontal Ligament
Tooth
Regeneration
7 引用 (Scopus)

Periodontal tissue engineering: Defining the triad

Maeda, H., Fujii, S., Tomokiyo, A., Wada, N. & Akamine, A., 1 1 2013, : : International Journal of Oral and Maxillofacial Implants. 28, 6, p. e461-e471

研究成果: ジャーナルへの寄稿記事

Periodontal Ligament
Tissue Engineering
Stem Cells
Cell Line
Phenotype
23 引用 (Scopus)

Prospective potency of TGF-β1 on maintenance and regeneration of periodontal tissue

Maeda, H., Wada, N., Tomokiyo, A., Monnouchi, S. & Akamine, A., 1 1 2013, International Review of Cell and Molecular Biology. Elsevier Inc., p. 283-367 85 p. (International Review of Cell and Molecular Biology; 巻数 304).

研究成果: 著書/レポートタイプへの貢献

Periodontal Ligament
Ligaments
Regeneration
Maintenance
Tissue
9 引用 (Scopus)

Quantitative single-nucleotide polymorphism analysis in secondary-structured DNA by affinity capillary electrophoresis using a polyethylene glycol-peptide nucleic acid block copolymer

Tsukada, H., Kundu, L. M., Matsuoka, Y., Kanayama, N., Takarada, T. & Maeda, M., 2 15 2013, : : Analytical Biochemistry. 433, 2, p. 150-152 3 p.

研究成果: ジャーナルへの寄稿記事

Peptide Nucleic Acids
Capillary electrophoresis
Capillary Electrophoresis
Polymorphism
Block copolymers
28 引用 (Scopus)

Regeneration of periodontal tissues using allogeneic periodontal ligament stem cells in an ovine model

Mrozik, K. M., Wada, N., Marino, V., Richter, W., Shi, S., Wheeler, D. L., Gronthos, S. & Bartold, P. M., 11 2013, : : Regenerative Medicine. 8, 6, p. 711-723 13 p.

研究成果: ジャーナルへの寄稿記事

Absorbable Gelatin Sponge
Periodontal Ligament
Ligaments
Stem cells
Regeneration
2014

Effect of a rotation training system on the mental health status of postgraduate dental trainees at Kyushu University Hospital, Fukuoka, Japan

Takarada, T., Asada, T., Sumi, Y. & Higuchi, Y., 2 1 2014, : : Journal of dental education. 78, 2, p. 243-249 7 p.

研究成果: ジャーナルへの寄稿記事

trainee
Health Status
health status
Tooth
Mental Health
4 引用 (Scopus)

Effects of Activin A on the phenotypic properties of human periodontal ligament cells

Sugii, H., Maeda, H., Tomokiyo, A., Yamamoto, N., Wada, N., Koori, K., Hasegawa, D., Hamano, S., Yuda, A., Monnouchi, S. & Akamine, A., 1 1 2014, : : Bone. 66, p. 62-71 10 p.

研究成果: ジャーナルへの寄稿記事

Periodontal Ligament
Cell Differentiation
Interleukin-1
Tooth Root
activin A
7 引用 (Scopus)

Expression and effects of epidermal growth factor on human periodontal ligament cells

Teramatsu, Y., Maeda, H., Sugii, H., Tomokiyo, A., Hamano, S., Wada, N., Yuda, A., Yamamoto, N., Koori, K. & Akamine, A., 9 1 2014, : : Cell and tissue research. 357, 3, p. 633-643 11 p.

研究成果: ジャーナルへの寄稿記事

Periodontal Ligament
Epidermal Growth Factor
Interleukin-1
Epidermal Growth Factor Receptor
Bone Morphogenetic Protein 2
6 引用 (Scopus)

Inhibition of JNK in HaCaT cells induced tight junction formation with decreased expression of cytokeratin 5, cytokeratin 17 and desmoglein 3

Kitagawa, N., Inai, Y., Higuchi, Y., Iida, H. & Inai, T., 1 1 2014, : : Histochemistry and Cell Biology. 142, 4, p. 389-399 11 p.

研究成果: ジャーナルへの寄稿記事

Keratin-17
Keratin-3
Desmoglein 3
Keratin-5
JNK Mitogen-Activated Protein Kinases
49 引用 (Scopus)

Periodontal-ligament-derived stem cells exhibit the capacity for long-term survival, self-renewal, and regeneration of multiple tissue types in vivo

Menicanin, D., Mrozik, K. M., Wada, N., Marino, V., Shi, S., Bartold, P. M. & Gronthos, S., 5 1 2014, : : Stem Cells and Development. 23, 9, p. 1001-1011 11 p.

研究成果: ジャーナルへの寄稿記事

Periodontal Ligament
Regeneration
Stem Cells
Deoxyuridine
Transplants
11 引用 (Scopus)

Porphyromonas gingivalis gingipain is involved in the detachment and aggregation of Aggregatibacter actinomycetemcomitans biofilm

Haraguchi, A., Miura, M., Fujise, O., Hamachi, T. & Nishimura, F., 1 1 2014, : : Molecular Oral Microbiology. 29, 3, p. 131-143 13 p.

研究成果: ジャーナルへの寄稿記事

Aggregatibacter actinomycetemcomitans
Porphyromonas gingivalis
Biofilms
Peptide Hydrolases
Cysteine Proteases
5 引用 (Scopus)

Possible involvement of ΔNp63 downregulation in the invasion and metastasis of oral squamous cell carcinoma via induction of a mesenchymal phenotype

Goto, Y., Kawano, S., Matsubara, R., Kiyosue, T., Hirano, M., Jinno, T., Maruse, Y., Toyoshima, T., kitamura, R., Tanaka, H., Oobu, K. & Nakamura, S., 1 1 2014, : : Clinical and Experimental Metastasis. 31, 3, p. 293-306 14 p.

研究成果: ジャーナルへの寄稿記事

Squamous Cell Carcinoma
Down-Regulation
Neoplasm Metastasis
Phenotype
Epithelial-Mesenchymal Transition
3 引用 (Scopus)

Regeneration of the periodontium for preservation of the damaged tooth

Maeda, H., Tomokiyo, A., Wada, N., Koori, K., Kawachi, G. & Akamine, A., 10 1 2014, : : Histology and histopathology. 29, 10, p. 1249-1262 14 p.

研究成果: ジャーナルへの寄稿評論記事

Periodontium
Regeneration
Tooth Loss
Tooth
Periodontitis
15 引用 (Scopus)

Semaphorin 3A induces mesenchymal-stem-like properties in human periodontal ligament cells

Wada, N., Maeda, H., Hasegawa, D., Gronthos, S., Bartold, P. M., Menicanin, D., Fujii, S., Yoshida, S., Tomokiyo, A., Monnouchi, S. & Akamine, A., 9 15 2014, : : Stem Cells and Development. 23, 18, p. 2225-2236 12 p.

研究成果: ジャーナルへの寄稿記事

Semaphorin-3A
Periodontal Ligament
Stem Cells
Mesenchymal Stromal Cells
Tooth
20 引用 (Scopus)
Calcium-Sensing Receptors
Periodontal Ligament
Calcium Channels
Stem Cells
Calcium
2015
12 引用 (Scopus)

Effect of CTGF/CCN2 on osteo/ cementoblastic and fibroblastic differentiation of a human periodontal ligament stem/progenitor cell line

Yuda, A., Maeda, H., Fujii, S., Monnouchi, S., Yamamoto, N., Wada, N., Koori, K., Tomokiyo, A., Hamano, S., Hasegawa, D. & Akamine, A., 1 1 2015, : : Journal of cellular physiology. 230, 1, p. 150-159 10 p.

研究成果: ジャーナルへの寄稿記事

Periodontal Ligament
Ligaments
Stem cells
Stem Cells
Cell Line
43 引用 (Scopus)

Increased expression of interleukin-6 predicts poor response to chemoradiotherapy and unfavorable prognosis in oral squamous cell carcinoma

Jinno, T., Kawano, S., Maruse, Y., Matsubara, R., Goto, Y., Sakamoto, T., Hashiguchi, Y., Kaneko, N., Tanaka, H., Kitamura, R., Toyoshima, T., Jinno, A., Moriyama, M., Oobu, K., Kiyoshima, T. & Nakamura, S., 5 1 2015, : : Oncology reports. 33, 5, p. 2161-2168 8 p.

研究成果: ジャーナルへの寄稿記事

Chemoradiotherapy
Squamous Cell Carcinoma
Interleukin-6
Interleukin-6 Receptors
Neoplasms
13 引用 (Scopus)

Mechanical induction of interleukin-11 regulates osteoblastic/cementoblastic differentiation of human periodontal ligament stem/progenitor cells

Monnouchi, S., Maeda, H., Yuda, A., Hamano, S., Wada, N., Tomokiyo, A., Koori, K., Sugii, H., Serita, S. & Akamine, A., 4 1 2015, : : Journal of Periodontal Research. 50, 2, p. 231-239 9 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-11
Periodontal Ligament
Stem Cells
Angiotensin II
Cell Line
12 引用 (Scopus)

Microbial community in persistent apical periodontitis: A 16S rRNA gene clone library analysis

Zakaria, M. N., Takeshita, T., Shibata, Y., Maeda, H., Wada, N., Akamine, A. & Yamashita, Y., 1 1 2015, : : International Endodontic Journal. 48, 8, p. 717-728 12 p.

研究成果: ジャーナルへの寄稿記事

Periapical Periodontitis
Porphyromonas gingivalis
Gene Library
rRNA Genes
Clone Cells
18 引用 (Scopus)

Modulation of Interparticle Distance in Discrete Gold Nanoparticle Dimers and Trimers by DNA Single-Base Pairing

Akiyama, Y., Shikagawa, H., Kanayama, N., Takarada, T. & Maeda, M., 7 1 2015, : : Small. 11, 26, p. 3153-3161 9 p.

研究成果: ジャーナルへの寄稿記事

Base Pairing
Gold
Dimers
Nanoparticles
DNA
1 引用 (Scopus)

Noncontact monitoring of respiration by dynamic air-pressure sensor

Takarada, T., Asada, T., Sumi, Y. & Higuchi, Y., 9 1 2015, : : Anesthesia progress. 62, 3, p. 100-105 6 p.

研究成果: ジャーナルへの寄稿記事

Air Pressure
Respiration
Clothing
Tidal Volume
Tooth
18 引用 (Scopus)

Saliva as a potential tool for diagnosis of dry mouth including Sjögren's syndrome

Ohyama, K., Moriyama, M., Hayashida, J. N., Tanaka, A., Maehara, T., Ieda, S., Furukawa, S., Ohta, M., Imabayashi, Y. & Nakamura, S., 3 1 2015, : : Oral Diseases. 21, 2, p. 224-231 8 p.

研究成果: ジャーナルへの寄稿記事

Saliva
Mouth
Xerostomia
Chromogranin A
Secretory Immunoglobulin A
14 引用 (Scopus)
Periodontal Ligament
Ligaments
Up-Regulation
Collagen
Tissue
2016

Antibiotic effects against periodontal bacteria in organ cultured tissue

Takeshita, M., Haraguchi, A., Miura, M., Hamachi, T., Fukuda, T., Sanui, T., Takano, A. & Nishimura, F., 11 2016, (受理済み/印刷中) : : Clinical and Experimental Dental Research.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)
Aryl Hydrocarbon Receptors
Periodontal Ligament
Benzo(a)pyrene
Collagen
Cyclic Hydrocarbons
3 引用 (Scopus)

Clinicopathological evaluation of pre-operative chemoradiotherapy with S-1 as a treatment for locally advanced oral squamous cell carcinoma

Kawano, S., Zheng, Y., Oobu, K., Matsubara, R., Goto, Y., Chikui, T., Yoshitake, T., Kiyoshima, T., Jinno, T., Maruse, Y., Mitate, E., Kitamura, R., Tanaka, H., Toyoshima, T., Sugiura, T. & Nakamura, S., 5 2016, : : Oncology Letters. 11, 5, p. 3369-3376 8 p.

研究成果: ジャーナルへの寄稿記事

Chemoradiotherapy
Squamous Cell Carcinoma
Therapeutics
Radiotherapy
Survival Rate

Contribution of Stem Cells to Dental Tissue Regeneration: Isolation, Function, and Application.

Tomokiyo, A., Wada, N. & Maeda, H., 2016, Frontiers in Stem Cell and Regenerative Medicine Research. Bentham Science Publishers, 巻 2. p. 3-38 36 p.

研究成果: 著書/レポートタイプへの貢献

Parathyroid Hormone-Related Protein
Organized Financing
Granulocyte Colony-Stimulating Factor
Tongue
Sports
5 引用 (Scopus)

Facioscapulohumeral muscular dystrophy (FSHD) region gene 1 (FRG1) expression and possible function in mouse tooth germ development

Hasegawa, K., Wada, H., Nagata, K., Fujiwara, H., Wada, N., Someya, H., Mikami, Y., Sakai, H. & Kiyoshima, T., 8 1 2016, : : Journal of Molecular Histology. 47, 4, p. 375-387 13 p.

研究成果: ジャーナルへの寄稿記事

Facioscapulohumeral Muscular Dystrophy
Tooth Germ
Gene Expression
Genes
Cytoplasm
7 引用 (Scopus)

Rapid Naked-Eye Discrimination of Cytochrome P450 Genetic Polymorphism through Non-Crosslinking Aggregation of DNA-Functionalized Gold Nanoparticles

Akiyama, Y., Wang, G., Shiraishi, S., Kanayama, N., Takarada, T. & Maeda, M., 12 1 2016, : : ChemistryOpen. 5, 6, p. 508-512 5 p.

研究成果: ジャーナルへの寄稿記事

Polymorphism
Gold
Cytochrome P-450 Enzyme System
Assays
Agglomeration
14 引用 (Scopus)

Semaphorin 3A induces odontoblastic phenotype in dental pulp stem cells

Yoshida, S., Wada, N., Hasegawa, D., Miyaji, H., Mitarai, H., Tomokiyo, A., Hamano, S. & Maeda, H., 10 1 2016, : : Journal of Dental Research. 95, 11, p. 1282-1290 9 p.

研究成果: ジャーナルへの寄稿記事

Semaphorin-3A
Dental Pulp
Stem Cells
Dentin
Phenotype
2 引用 (Scopus)

Tongue squamous cell carcinoma producing both parathyroid hormone-related protein and granulocyte colony-stimulating factor: A case report and literature review

Kaneko, N., Kawano, S., Matsubara, R., Goto, Y., Jinno, T., Maruse, Y., Sakamoto, T., Hashiguchi, Y., Iida, M. & Nakamura, S., 6 17 2016, : : World Journal of Surgical Oncology. 14, 1, 161.

研究成果: ジャーナルへの寄稿記事

Parathyroid Hormone-Related Protein
Hypercalcemia
Granulocyte Colony-Stimulating Factor
Tongue
Squamous Cell Carcinoma
2017

Antibiotic effects against periodontal bacteria in organ cultured tissue

Takeshita, M., Haraguchi, A., Miura, M., Hamachi, T., Fukuda, T., Sanui, T., Takano, A. & Nishimura, F., 2 1 2017, : : Clinical and Experimental Dental Research. 3, 1, p. 5-12 8 p.

研究成果: ジャーナルへの寄稿記事

Epithelium
Anti-Bacterial Agents
Bacteria
cefdinir
Periodontitis
1 引用 (Scopus)
Anti-Idiotypic Antibodies
Neutrophils
Toll-Like Receptor 4
Superoxides
Lipids
12 引用 (Scopus)

Calcium-sensing receptor-ERK signaling promotes odontoblastic differentiation of human dental pulp cells

Mizumachi, H., Yoshida, S., Tomokiyo, A., Hasegawa, D., Hamano, S., Yuda, A., Sugii, H., Serita, S., Mitarai, H., Koori, K., Wada, N. & Maeda, H., 8 1 2017, : : Bone. 101, p. 191-201 11 p.

研究成果: ジャーナルへの寄稿記事

Calcium-Sensing Receptors
Dental Pulp
Strontium
Calcium
L-Type Calcium Channels
30 引用 (Scopus)

CD163 + CD204 + tumor-associated macrophages contribute to T cell regulation via interleukin-10 and PD-L1 production in oral squamous cell carcinoma

Kubota, K., Moriyama, M., Furukawa, S., Rafiul, H. A. S. M., Maruse, Y., Jinno, T., Tanaka, A., Ohta, M., Ishiguro, N., Yamauchi, M., Sakamoto, M., Maehara, T., Hayashida, J. N., Kawano, S., Kiyoshima, T. & Nakamura, S., 12 1 2017, : : Scientific reports. 7, 1, 1755.

研究成果: ジャーナルへの寄稿記事

Interleukin-10
Squamous Cell Carcinoma
Macrophages
T-Lymphocytes
Neoplasms
5 引用 (Scopus)

Critical roles of Wnt5a–Ror2 signaling in aggressiveness of tongue squamous cell carcinoma and production of matrix metalloproteinase-2 via ΔNp63β-mediated epithelial–mesenchymal transition

Sakamoto, T., Kawano, S., Matsubara, R., Goto, Y., Jinno, T., Maruse, Y., Kaneko, N., Hashiguchi, Y., Hattori, T., Tanaka, S., kitamura, R., Kiyoshima, T. & Nakamura, S., 6 1 2017, : : Oral Oncology. 69, p. 15-25 11 p.

研究成果: ジャーナルへの寄稿記事

Matrix Metalloproteinase 2
Tongue
Squamous Cell Carcinoma
Cell Movement
B-Lymphocytes
16 引用 (Scopus)

Cross-linking versus non-cross-linking aggregation of gold nanoparticles induced by DNA hybridization: A comparison of the rapidity of solution color change

Wang, G., Akiyama, Y., Shiraishi, S., Kanayama, N., Takarada, T. & Maeda, M., 1 1 2017, : : Bioconjugate Chemistry. 28, 1, p. 270-277 8 p.

研究成果: ジャーナルへの寄稿記事

Gold
Nanoparticles
DNA
Agglomeration
Color
2 引用 (Scopus)

Cytokeratin 17 mRNA as a prognostic marker of oral squamous cell carcinoma

Kitamura, R., Toyoshima, T., Tanaka, H., Kawano, S., Matsubara, R., Goto, Y., Jinno, T., Maruse, Y., Oobu, K. & Nakamura, S., 12 2017, : : Oncology Letters. 14, 6, p. 6735-6743 9 p.

研究成果: ジャーナルへの寄稿記事

Keratin-17
Squamous Cell Carcinoma
Messenger RNA
Blood Cells
Survival Rate
1 引用 (Scopus)

Differential roles of kallikrein-related peptidase 6 in malignant transformation and ΔNp63β-mediated epithelial-mesenchymal transition of oral squamous cell carcinoma

Kaneko, N., Kawano, S., Yasuda, K., Hashiguchi, Y., Sakamoto, T., Matsubara, R., Goto, Y., Jinno, T., Maruse, Y., Morioka, M., Hattori, T., Tanaka, S., Tanaka, H., Kiyoshima, T. & Nakamura, S., 12 1 2017, : : Oral Oncology. 75, p. 148-157 10 p.

研究成果: ジャーナルへの寄稿記事

Kallikreins
Epithelial-Mesenchymal Transition
Squamous Cell Carcinoma
Peptide Hydrolases
Epithelium
Glial Cell Line-Derived Neurotrophic Factor
Periodontal Ligament
PC12 Cells
Ligaments
Interleukin-1beta
4 引用 (Scopus)
Porphyromonas gingivalis
Neutrophils
Toll-Like Receptor 4
Respiratory Burst
Interleukin-1
22 引用 (Scopus)

Iodine-mediated etching of triangular gold nanoplates for colorimetric sensing of copper ion and aptasensing of chloramphenicol

Chang, C. C., Wang, G., Takarada, T. & Maeda, M., 1 1 2017, : : ACS Applied Materials and Interfaces. 9, 39, p. 34518-34525 8 p.

研究成果: ジャーナルへの寄稿記事

Chloramphenicol
Iodine
Gold
Copper
Etching
2 引用 (Scopus)

Transforming growth factor-β-induced gene product-h3 inhibits odontoblastic differentiation of dental pulp cells

Serita, S., Tomokiyo, A., Hasegawa, D., Hamano, S., Sugii, H., Yoshida, S., Mizumachi, H., Mitarai, H., Monnouchi, S., Wada, N. & Maeda, H., 6 1 2017, : : Archives of Oral Biology. 78, p. 135-143 9 p.

研究成果: ジャーナルへの寄稿記事

Dental Pulp
Transforming Growth Factors
Odontoblasts
Genes
Dental Pulp Capping
3 引用 (Scopus)

Transgelin mediates transforming growth factor-β1-induced proliferation of human periodontal ligament cells

Mitarai, H., Wada, N., Hasegawa, D., Yoshida, S., Sonoda, M., Tomokiyo, A., Hamano, S., Serita, S., Mizumachi, H. & Maeda, H., 12 1 2017, : : Journal of Periodontal Research. 52, 6, p. 984-993 10 p.

研究成果: ジャーナルへの寄稿記事

Periodontal Ligament
Transforming Growth Factors
Small Interfering RNA
Fluorescent Antibody Technique
transgelin
2018
6 引用 (Scopus)
Induced Pluripotent Stem Cells
Periodontal Ligament
Neural Crest
Extracellular Matrix
Stem Cells