研究成果

2018

Direct reprogramming of spiral ganglion non-neuronal cells into neurons: Toward ameliorating sensorineural hearing loss by gene therapy

Noda, T., Meas, S. J., Nogami, J., Amemiya, Y., Uchi, R., Ohkawa, Y., Nishimura, K. & Dabdoub, A., 2 14 2018, : : Frontiers in Cell and Developmental Biology. 6, FEB, 16.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Direct visualization of DNA baton pass between replication factors bound to PCNA

Mayanagi, K., Ishino, S., Shirai, T., Oyama, T., Kiyonari, S., Kohda, D., Morikawa, K. & Ishino, Y., 12 1 2018, : : Scientific reports. 8, 1, 16209.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

DNA methylation of the Klf14 gene region in whole blood cells provides prediction for the chronic inflammation in the adipose tissue

Iwaya, C., Kitajima, H., Yamamoto, K., Maeda, Y., Sonoda, N., Shibata, H. & Inoguchi, T., 3 11 2018, : : Biochemical and Biophysical Research Communications. 497, 3, p. 908-915 8 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activating Rac1P29S mutation

Tomino, T., Tajiri, H., Tatsuguchi, T., Shirai, T., Oisaki, K., Matsunaga, S., Sanematsu, F., Sakata, D., Yoshizumi, T., Maehara, Y., Kanai, M., Cote, J. F., Fukui, Y. & Uruno, T., 2 26 2018, : : Biochemical and Biophysical Research Communications. 497, 1, p. 298-304 7 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)
51 引用 (Scopus)
1 引用 (Scopus)

Erratum: Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding (Immunity (2018) 48(6) (1119–1134.e7), (S1074761318301936) (10.1016/j.immuni.2018.04.024))

Hosokawa, H., Ungerbäck, J., Wang, X., Matsumoto, M., Nakayama, K. I., Cohen, S. M., Tanaka, T. & Rothenberg, E. V., 10 16 2018, : : Immunity. 49, 4, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

1 引用 (Scopus)

Expression of CRYM in different rat organs during development and its decreased expression in degenerating pyramidal tracts in amyotrophic lateral sclerosis

Hommyo, R., Suzuki, S. O., Abolhassani, N., Hamasaki, H., Shijo, M., Maeda, N., Honda, H., Nakabeppu, Y. & Iwaki, T., 6 2018, : : Neuropathology. 38, 3, p. 247-259 13 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Fetal leydig cells dedifferentiate and serve as adult leydig stem cells

Shima, Y., Miyabayashi, K., Sato, T., Suyama, M., Ohkawa, Y., Doi, M., Okamura, H. & Suzuki, K., 12 2018, : : Development (Cambridge). 145, 23, dev169136.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Generation of human oogonia from induced pluripotent stem cells in vitro

Yamashiro, C., Sasaki, K., Yabuta, Y., Kojima, Y., Nakamura, T., Okamoto, I., Yokobayashi, S., Murase, Y., Ishikura, Y., Shirane, K., Sasaki, H., Yamamoto, T. & Saitou, M., 10 19 2018, : : Science. 362, 6412, p. 356-360 5 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., 7 27 2018, : : Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

Glucocorticoids Drive Diurnal Oscillations in T Cell Distribution and Responses by Inducing Interleukin-7 Receptor and CXCR4

Shimba, A., Cui, G., Tani-ichi, S., Ogawa, M., Abe, S., Okazaki, F., Kitano, S., Miyachi, H., Yamada, H., Hara, T., Yoshikai, Y., Nagasawa, T., Schütz, G. & Ikuta, K., 2 20 2018, : : Immunity. 48, 2, p. 286-298.e6

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., 8 1 2018, : : Journal of cell science. 131, 15

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Hidden peptides encoded by putative noncoding RNAs

Matsumoto, A. & Nakayama, K. I., 1 1 2018, : : Cell structure and function. 43, 1, p. 75-83 9 p.

研究成果: ジャーナルへの寄稿小調査

15 引用 (Scopus)

High affinity sugar ligands of C-type lectin receptor langerin

Ota, F., Hirayama, T., Kizuka, Y., Yamaguchi, Y., Fujinawa, R., Nagata, M., Ismanto, H. S., Lepenies, B., Aretz, J., Rademacher, C., Seeberger, P. H., Angata, T., Kitazume, S., Yoshida, K., Betsuyaku, T., Kida, K., Yamasaki, S. & Taniguchi, N., 7 2018, : : Biochimica et Biophysica Acta - General Subjects. 1862, 7, p. 1592-1601 10 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Highly Accurate Detection and Identification Methodology of Xenobiotic Metabolites Using Stable Isotope Labeling, Data Mining Techniques, and Time-Dependent Profiling Based on LC/HRMS/MS

Takahashi, M., Izumi, Y., Iwahashi, F., Nakayama, Y., Iwakoshi, M., Nakao, M., Yamato, S., Fukusaki, E. & Bamba, T., 8 7 2018, : : Analytical chemistry. 90, 15, p. 9068-9076 9 p.

研究成果: ジャーナルへの寄稿記事

Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration

Harada, A., Maehara, K., Ono, Y., Taguchi, H., Yoshioka, K., Kitajima, Y., Xie, Y., Sato, Y., Iwasaki, T., Nogami, J., Okada, S., Komatsu, T., Semba, Y., Takemoto, T., Kimura, H., Kurumizaka, H. & Ohkawa, Y., 12 1 2018, : : Nature communications. 9, 1, 1400.

研究成果: ジャーナルへの寄稿記事

Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia

Nagao, H., Nishizawa, H., Tanaka, Y., Fukata, T., Mizushima, T., Furuno, M., Bamba, T., Tsushima, Y., Fujishima, Y., Kita, S., Funahashi, T., Maeda, N., Mori, M., Fukusaki, E. & Shimomura, I., 7 2018, : : Obesity. 26, 7, p. 1168-1178 11 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Identification of a candidate enhancer for DMRT3 involved in spastic cerebral palsy pathogenesis

Kubota, N., Yokoyama, T., Hoshi, N. & Suyama, M., 1 29 2018, : : Biochemical and Biophysical Research Communications. 496, 1, p. 133-139 7 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Identification of miR-305, a microRNA that promotes aging, and its target mRNAs in Drosophila

Ueda, M., Sato, T., Ohkawa, Y. & Inoue, Y. H., 2 1 2018, : : Genes to Cells. 23, 2, p. 80-93 14 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Identification of the physiological substrates of PDIp, a pancreas-specific protein-disulfide isomerase family member

Fujimoto, T., Nakamura, O., Saito, M., Tsuru, A., Matsumoto, M., Kohno, K., Inaba, K. & Kadokura, H., 1 1 2018, : : Journal of Biological Chemistry. 293, 48, p. 18421-18433 13 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Identifying metabolic elements that contribute to productivity of 1-propanol bioproduction using metabolomic analysis

Putri, S. P., Nakayama, Y., Shen, C., Noguchi, S., Nitta, K., Bamba, T., Pontrelli, S., Liao, J. & Fukusaki, E., 7 1 2018, : : Metabolomics. 14, 7, 96.

研究成果: ジャーナルへの寄稿記事

Increase in hepatic and decrease in peripheral insulin clearance characterize abnormal temporal patterns of serum insulin in diabetic subjects

Ohashi, K., Fujii, M., Uda, S., Kubota, H., Komada, H., Sakaguchi, K., Ogawa, W. & Kuroda, S., 2018, : : npj Systems Biology and Applications. 4, 14.

研究成果: ジャーナルへの寄稿記事

公開

Increase in hepatic and decrease in peripheral insulin clearance characterize abnormal temporal patterns of serum insulin in diabetic subjects

Ohashi, K., Fujii, M., Uda, S., Kubota, H., Komada, H., Sakaguchi, K., Ogawa, W. & Kuroda, S., 12 1 2018, : : npj Systems Biology and Applications. 4, 1, 14.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Inhibiting Skp2 E3 ligase suppresses bleomycin-induced pulmonary fibrosis

Mikamo, M., Kitagawa, K., Sakai, S., Uchida, C., Ohhata, T., Nishimoto, K., Niida, H., Suzuki, S., Nakayama, K. I., Inui, N., Suda, T. & Kitagawa, M., 2 6 2018, : : International journal of molecular sciences. 19, 2, 474.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Insulin-like growth factor 1 receptor stabilizes the ETV6-NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation

Tognon, C. E., Rafn, B., Cetinbas, N. M., Kamura, T., Trigo, G., Rotblat, B., Okumura, F., Matsumoto, M., Chow, C., Davare, M., Pollak, M., Mayor, T. & Sorensen, P. H., 1 1 2018, : : Journal of Biological Chemistry. 293, 32, p. 12502-12515 14 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Integrated analysis of microRNA and mRNA expression profiles in splenomegaly induced by non-cirrhotic portal hypertension in rats

Saruwatari, J., Dong, C., Utsumi, T., Tanaka, M., McConnell, M. & Iwakiri, Y., 12 1 2018, : : Scientific reports. 8, 1, 17983.

研究成果: ジャーナルへの寄稿記事

Interleukin-21 induces short-lived effector CD8 + T cells but does not inhibit their exhaustion after Mycobacterium bovis BCG infection in mice

Noguchi, N., Nakamura, R., Hatano, S., Yamada, H., Sun, X., Ohara, N. & Yoshikai, Y., 8 1 2018, : : Infection and Immunity. 86, 8, e00147-18.

研究成果: ジャーナルへの寄稿記事

公開
1 引用 (Scopus)

Intratumor heterogeneity of HMCN1 mutant alleles associated with poor prognosis in patients with breast cancer

Kikutake, C., Yoshihara, M., Sato, T., Saito, D. & Suyama, M., 9 1 2018, : : Oncotarget. 9, 70, p. 33337-33347 11 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver

Kubota, H., Uda, S., Matsuzaki, F., Yamauchi, Y. & Kuroda, S., 7 25 2018, : : Cell Systems. 7, 1, p. 118-128.e3

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Linear ubiquitin chain-binding domains

Fennell, L. M., Rahighi, S. & Ikeda, F., 8 2018, : : FEBS Journal. 285, 15, p. 2746-2761 16 p.

研究成果: ジャーナルへの寄稿評論記事

公開
5 引用 (Scopus)

Lipidated Brartemicin Analogues Are Potent Th1-Stimulating Vaccine Adjuvants

Foster, A. J., Nagata, M., Lu, X., Lynch, A. T., Omahdi, Z., Ishikawa, E., Yamasaki, S., Timmer, M. S. M. & Stocker, B. L., 2 8 2018, : : Journal of Medicinal Chemistry. 61, 3, p. 1045-1060 16 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Matrix rank minimization approach to signal recovery and nonlinear function estimation for nonlinear ARX model with input nonlinearity

Konishi, K., Fujii, M., Kunida, K., Uda, S. & Kuroda, S., 2 8 2018, Control Conference (ASCC), 2017 11th Asian. IEEE

研究成果: 著書/レポートタイプへの貢献会議での発言

Matrix rank minimization approach to signal recovery and nonlinear function estimation for nonlinear ARX model with input nonlinearity

Konishi, K., Fujii, M., Kunida, K., Uda, S. & Kuroda, S., 2 7 2018, 2017 Asian Control Conference, ASCC 2017. Institute of Electrical and Electronics Engineers Inc., p. 1428-1431 4 p. (2017 Asian Control Conference, ASCC 2017; 巻数 2018-January).

研究成果: 著書/レポートタイプへの貢献会議での発言

Metabolomics approach to reduce the Crabtree effect in continuous culture of Saccharomyces cerevisiae

Imura, M., Iwakiri, R., Bamba, T. & Fukusaki, E., 8 2018, : : Journal of Bioscience and Bioengineering. 126, 2, p. 183-188 6 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Microbe participation in aroma production during soy sauce fermentation

Harada, R., Yuzuki, M., Ito, K., Shiga, K., Bamba, T. & Fukusaki, E., 6 2018, : : Journal of Bioscience and Bioengineering. 125, 6, p. 688-694 7 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Mitochondrial p32/C1qbp Is a Critical Regulator of Dendritic Cell Metabolism and Maturation

Gotoh, K., Morisaki, T., Setoyama, D., Sasaki, K., Yagi, M., Igami, K., Mizuguchi, S., Uchiumi, T., Fukui, Y. & Kang, D., 11 13 2018, : : Cell Reports. 25, 7, p. 1800-1815.e4

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

MNase, as a probe to study the sequence-dependent site exposures in the +1 nucleosomes of yeast

Luo, D., Kato, D., Nogami, J., Ohkawa, Y., Kurumizaka, H. & Kono, H., 1 1 2018, : : Nucleic acids research. 46, 14, p. 7124-7137 14 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Nuclear–cytoplasmic shuttling protein PP2AB56 contributes to mTORC1-dependent dephosphorylation of FOXK1

Nakatsumi, H., Oka, T., Higa, T., Shirane, M. & Nakayama, K. I., 7 2018, : : Genes to Cells. 23, 7, p. 599-605 7 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Pan-cancer analysis of intratumor heterogeneity associated with patient prognosis using multidimensional measures

Kikutake, C., Yoshihara, M., Sato, T., Saito, D. & Suyama, M., 12 1 2018, : : Oncotarget. 9, 102, p. 37689-37699 11 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Periostin Promotes Fibroblast Migration and Inhibits Muscle Repair After Skeletal Muscle Injury

Hara, M., Yokota, K., Saito, T., Kobayakawa, K., Kijima, K., Yoshizaki, S., Okazaki, K., Yoshida, S., Matsumoto, Y., Harimaya, K., Nakashima, Y. & Okada, S., 8 15 2018, : : The Journal of bone and joint surgery. American volume. 100, 16, p. e108

研究成果: ジャーナルへの寄稿記事

Peroxisome biogenesis deficiency attenuates the BDNF-TrkB pathway-mediated development of the cerebellum

Abe, Y., Honsho, M., Itoh, R., Kawaguchi, R., Fujitani, M., Fujiwara, K., Hirokane, M., Matsuzaki, T., Nakayama, K., Ohgi, R., Marutani, T., Nakayama, K. I., Yamashita, T. & Fujiki, Y., 1 1 2018, : : Life Science Alliance. 1, 6

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Phosphorylation of the Ribosomal Protein RPL12/uL11 Affects Translation during Mitosis

Imami, K., Milek, M., Bogdanow, B., Yasuda, T., Kastelic, N., Zauber, H., Ishihama, Y., Landthaler, M. & Selbach, M., 10 4 2018, : : Molecular Cell. 72, 1, p. 84-98.e9

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth

Morita, M., Sato, T., Nomura, M., Sakamoto, Y., Inoue, Y., Tanaka, R., Ito, S., Kurosawa, K., Yamaguchi, K., Sugiura, Y., Takizaki, H., Yamashita, Y., Katakura, R., Sato, I., Kawai, M., Okada, Y., Watanabe, H., Kondoh, G., Matsumoto, S., Kishimoto, A. および12人, Obata, M., Matsumoto, M., Fukuhara, T., Motohashi, H., Suematsu, M., Komatsu, M., Nakayama, K. I., Watanabe, T., Soga, T., Shima, H., Maemondo, M. & Tanuma, N., 3 12 2018, : : Cancer Cell. 33, 3, p. 355-367.e7

研究成果: ジャーナルへの寄稿記事

28 引用 (Scopus)

Polycomb protein SCML2 facilitates H3K27me3 to establish bivalent domains in the male germline

Maezawa, S., Hasegawa, K., Yukawa, M., Kubo, N., Sakashita, A., Alavattam, K. G., Sin, H. S., Kartashov, A. V., Sasaki, H., Barski, A. & Namekawa, S. H., 5 8 2018, : : Proceedings of the National Academy of Sciences of the United States of America. 115, 19, p. 4957-4962 6 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Predicting inhibitory and activatory drug targets by chemically and genetically perturbed transcriptome signatures

Sawada, R., Iwata, M., Tabei, Y., Yamato, H. & Yamanishi, Y., 12 1 2018, : : Scientific reports. 8, 1, 156.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors

Takashima, Y., Horisawa, K., Udono, M., Ohkawa, Y. & Suzuki, A., 11 1 2018, : : Cancer Science. 109, 11, p. 3543-3553 11 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Regulation of Pathogenic T Helper 17 Cell Differentiation by Steroid Receptor Coactivator-3

Tanaka, K., Martinez, G. J., Yan, X., Long, W., Ichiyama, K., Chi, X., Kim, B. S., Reynolds, J. M., Chung, Y., Tanaka, S., Liao, L., Nakanishi, Y., Yoshimura, A., Zheng, P., Wang, X., Tian, Q., Xu, J., O'Malley, B. W. & Dong, C., 5 22 2018, : : Cell Reports. 23, 8, p. 2318-2329 12 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Reprogramming of Th1 cells into regulatory T cells through rewiring of the metabolic status

Kanamori, M., Nakatsukasa, H., Ito, M., Chikuma, S. & Yoshimura, A., 1 1 2018, : : International immunology. 30, 8, p. 357-373 17 p.

研究成果: ジャーナルへの寄稿記事