研究成果 1979 2020

2017

2-Oxoadenosine induces cytotoxicity through intracellular accumulation of 2-oxo-ATP and depletion of ATP but not via the p38 MAPK pathway

Asada, S., Ohta, E., Akimoto, Y., Abolhassani, N., Tsuchimoto, D. & Nakabeppu, Y., 12 1 2017, : : Scientific Reports. 7, 1, 6528.

研究成果: ジャーナルへの寄稿記事

公開
Adenosine Kinase
p38 Mitogen-Activated Protein Kinases
Adenosine Triphosphate
Cell Death
Nucleoside-Triphosphatase
10 引用 (Scopus)

8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle

Vartanian, V., Tumova, J., Dobrzyn, P., Dobrzyn, A., Nakabeppu, Y., Lloyd, R. S. & Sampath, H., 7 2017, : : PloS one. 12, 7, e0181687.

研究成果: ジャーナルへの寄稿記事

DNA Glycosylases
glycosylases
Lipid Metabolism
Metabolism
Muscle

A case of amebiasis with negative serologic markers that caused intra-abdominal abscess

Tanaka, R., Furusyo, N., Takeda, R., Yamasaki, S., Kusaga, A., Ogawa, E., Masayuki, M., Nakanishi, R. & Maehara, Y., 11 1 2017, : : Journal of Infection and Chemotherapy. 23, 11, p. 778-781 4 p.

研究成果: ジャーナルへの寄稿記事

Abdominal Abscess
Amebiasis
Abscess
Serology
Tomography
2 引用 (Scopus)

A deletion in the intergenic region upstream of Ednrb causes head spot in the rat strain KFRS4/Kyo

Yoshihara, M., Sato, T., Saito, D., Ohara, O., Kuramoto, T. & Suyama, M., 3 29 2017, : : BMC Genetics. 18, 1, 29.

研究成果: ジャーナルへの寄稿記事

Intergenic DNA
Head
Phenotype
Mutation
Melanocytes
29 引用 (Scopus)

A functional genomics predictive network model identifies regulators of inflammatory bowel disease

Peters, L. A., Perrigoue, J., Mortha, A., Iuga, A., Song, W. M., Neiman, E. M., Llewellyn, S. R., Di Narzo, A., Kidd, B. A., Telesco, S. E., Zhao, Y., Stojmirovic, A., Sendecki, J., Shameer, K., Miotto, R., Losic, B., Shah, H., Lee, E., Wang, M., Faith, J. J. および18人, Kasarskis, A., Brodmerkel, C., Curran, M., Das, A., Friedman, J. R., Fukui, Y., Humphrey, M. B., Iritani, B. M., Sibinga, N., Tarrant, T. K., Argmann, C., Hao, K., Roussos, P., Zhu, J., Zhang, B., Dobrin, R., Mayer, L. F. & Schadt, E. E., 10 1 2017, : : Nature genetics. 49, 10, p. 1437-1449 13 p.

研究成果: ジャーナルへの寄稿記事

Genomics
Inflammatory Bowel Diseases
Genome-Wide Association Study
Molecular Biology
25 引用 (Scopus)

A large-scale targeted proteomics assay resource based on an in vitro human proteome

Matsumoto, M., Matsuzaki, F., Oshikawa, K., Goshima, N., Mori, M., Kawamura, Y., Ogawa, K., Fukuda, E., Nakatsumi, H., Natsume, T., Fukui, K., Horimoto, K., Nagashima, T., Funayama, R., Nakayama, K. & Nakayama, K. I., 2 28 2017, : : Nature Methods. 14, 3, p. 251-258 8 p.

研究成果: ジャーナルへの寄稿記事

Proteome
Proteomics
Assays
Proteins
Monitoring
11 引用 (Scopus)

Alterations in Fetal Leydig Cell Gene Expression during Fetal and Adult Development

Miyabayashi, K., Shima, Y., Inoue, M., Sato, T., Baba, T., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 5 1 2017, : : Sexual Development. 11, 2, p. 53-63 11 p.

研究成果: ジャーナルへの寄稿記事

Leydig Cells
Fetal Development
Gene Expression
Testis
Mitochondrial Genes

A metabolite of dietary glucosylceramide from pineapples improves the skin barrier function in hairless mice

Kuwata, T., Hashimoto, T., Ohto, N., Kuwahara, H., Lee, J. W., Bamba, T. & Mizuno, M., 3 1 2017, : : Journal of Functional Foods. 30, p. 228-236 9 p.

研究成果: ジャーナルへの寄稿記事

Ananas
Glucosylceramides
Hairless Mouse
pineapples
interleukins
3 引用 (Scopus)

A novel missense variant (Gln220Arg) of GNB4 encoding guanine nucleotide-binding protein, subunit beta-4 in a Japanese family with autosomal dominant motor and sensory neuropathy

Miura, S., Morikawa, T., Fujioka, R., Noda, K., Kosaka, K., Taniwaki, T. & Shibata, H., 9 2017, : : European Journal of Medical Genetics. 60, 9, p. 474-478 5 p.

研究成果: ジャーナルへの寄稿記事

Guanine Nucleotides
Protein Subunits
Carrier Proteins
Exome
Lower Extremity
4 引用 (Scopus)

Antigen availability and DOCK2-driven motility govern CD4+ t cell interactions with dendritic cells in vivo

Ackerknecht, M., Gollmer, K., Germann, P., Ficht, X., Abe, J., Fukui, Y., Swoger, J., Ripoll, J., Sharpe, J. & Stein, J. V., 7 15 2017, : : Journal of Immunology. 199, 2, p. 520-530 11 p.

研究成果: ジャーナルへの寄稿記事

Cell Communication
Dendritic Cells
Antigens
T-Lymphocytes
Peptides
2 引用 (Scopus)

Asn-linked oligosaccharide chain of a crenarchaeon, Pyrobaculum calidifontis, is reminiscent of the eukaryotic high-mannose-type glycan

Fujinami, D., Taguchi, Y. & Kohda, D., 8 1 2017, : : Glycobiology. 27, 8, p. 701-712 12 p.

研究成果: ジャーナルへの寄稿記事

Pyrobaculum
Mannose
Oligosaccharides
Polysaccharides
Crenarchaeota
5 引用 (Scopus)

Association of MTH1 expression with the tumor malignant potential and poor prognosis in patients with resected lung cancer

Fujishita, T., Okamoto, T., Akamine, T., Takamori, S., Takada, K., Katsura, M., Toyokawa, G., Shoji, F., Shimokawa, M., Oda, Y., Nakabeppu, Y. & Maehara, Y., 7 1 2017, : : Lung Cancer. 109, p. 52-57 6 p.

研究成果: ジャーナルへの寄稿記事

Lung Neoplasms
Non-Small Cell Lung Carcinoma
Neoplasms
Antioxidants
Nucleoside-Triphosphatase
2 引用 (Scopus)

Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1

Sasaki, F., Koga, T., Saeki, K., Okuno, T., Kazuno, S., Fujimura, T., Ohkawa, Y. & Yokomizo, T., 9 2017, : : PloS one. 12, 9, e0185133.

研究成果: ジャーナルへの寄稿記事

leukotrienes
monoclonal antibodies
Monoclonal Antibodies
receptors
mice
1 引用 (Scopus)

Calcineurin inhibitors exacerbate coronary arteritis via the MyD88 signalling pathway in a murine model of Kawasaki disease

Murata, K., Motomura, Y., Tanaka, T., Kanno, S., Yano, T., Onimaru, M., Shimoyama, A., Nishio, H., Sakai, Y., Oh-Hora, M., Hara, H., Fukase, K., Takada, H., Masuda, S., Ohga, S., Yamasaki, S. & Hara, T., 10 2017, : : Clinical and Experimental Immunology. 190, 1, p. 54-67 14 p.

研究成果: ジャーナルへの寄稿記事

Arteritis
Mucocutaneous Lymph Node Syndrome
Blood Vessels
Severe Combined Immunodeficiency
Coronary Vessels

CD5NK1.1+ γδ T Cells that Develop in a Bcl11b-Independent Manner Participate in Early Protection against Infection

Hatano, S., Murakami, T., Noguchi, N., Yamada, H. & Yoshikai, Y., 10 31 2017, : : Cell Reports. 21, 5, p. 1191-1202 12 p.

研究成果: ジャーナルへの寄稿記事

B-Cell Leukemia
T-cells
B-Cell Lymphoma
Thymus
T-Lymphocytes
13 引用 (Scopus)

Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway

Egashira, I., Takahashi-Yanaga, F., Nishida, R., Arioka, M., Igawa, K., Tomooka, K., Nakatsu, Y., Tsuzuki, T., Nakabeppu, Y., Kitazono, T. & Sasaguri, T., 1 1 2017, : : Cancer Science. 108, 1, p. 108-115 8 p.

研究成果: ジャーナルへの寄稿記事

Celecoxib
Intestinal Neoplasms
Catenins
Wnt Signaling Pathway
Growth
1 引用 (Scopus)

Cell fate modification toward the hepatic lineage by extrinsic factors

Kawamata, M. & Suzuki, A., 7 1 2017, : : Journal of biochemistry. 162, 1, p. 11-16 6 p.

研究成果: ジャーナルへの寄稿評論記事

Stem cells
Liver
Hepatocytes
Induced Pluripotent Stem Cells
Fibroblasts
10 引用 (Scopus)

Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells

Semba, Y., Harada, A., Maehara, K., Oki, S., Meno, C., Ueda, J., Yamagata, K., Suzuki, A., Onimaru, M., Nogami, J., Okada, S., Akashi, K. & Ohkawa, Y., 9 1 2017, : : Nucleic acids research. 45, 15, p. 8758-8772 15 p.

研究成果: ジャーナルへの寄稿記事

DNA Helicases
Embryonic Stem Cells
Chromatin
Gene Expression
Histones
12 引用 (Scopus)

Chronic atypical antipsychotics, but not haloperidol, increase neurogenesis in the hippocampus of adult mouse

Chikama, K., Yamada, H., Tsukamoto, T., Kajitani, K., Nakabeppu, Y. & Uchimura, N., 12 1 2017, : : Brain Research. 1676, p. 77-82 6 p.

研究成果: ジャーナルへの寄稿記事

Neurogenesis
Haloperidol
Bromodeoxyuridine
olanzapine
Antipsychotic Agents
19 引用 (Scopus)

Comparative profiling of cortical gene expression in Alzheimer's disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Castillo, E., Leon, J., Mazzei, G., Abolhassani, N., Haruyama, N., Saito, T., Saido, T., Hokama, M., Iwaki, T., Ohara, T., Ninomiya, T., Kiyohara, Y., Sakumi, K., Laferla, F. M. & Nakabeppu, Y., 12 1 2017, : : Scientific reports. 7, 1, 17762.

研究成果: ジャーナルへの寄稿記事

Gene Expression Profiling
Amyloidosis
Alzheimer Disease
Genes
Neurofibrillary Tangles
5 引用 (Scopus)

Complexity of Stomach–Brain Interaction Induced by Molecular Hydrogen in Parkinson’s Disease Model Mice

Yoshii, Y., Inoue, T., Uemura, Y., Iwasaki, Y., Yada, T., Nakabeppu, Y. & Noda, M., 9 1 2017, : : Neurochemical Research. 42, 9, p. 2658-2665 8 p.

研究成果: ジャーナルへの寄稿記事

Ghrelin
Parkinson Disease
Hydrogen
Water
Knockout Mice
5 引用 (Scopus)

Control of tissue size and development by a regulatory element in the yorkie 3'UTR

Umegawachi, T., Yoshida, H., Koshida, H., Yamada, M., Ohkawa, Y., Sato, T., Suyama, M., Krause, H. M. & Yamaguchi, M., 1 1 2017, : : American Journal of Cancer Research. 7, 3, p. 673-687 15 p.

研究成果: ジャーナルへの寄稿記事

3' Untranslated Regions
Drosophila
Inverted Repeat Sequences
RNA
Imaginal Discs
50 引用 (Scopus)

Conversion of Terminally Committed Hepatocytes to Culturable Bipotent Progenitor Cells with Regenerative Capacity

Katsuda, T., Kawamata, M., Hagiwara, K., Takahashi, R. U., Yamamoto, Y., Camargo, F. D. & Ochiya, T., 1 5 2017, : : Cell stem cell. 20, 1, p. 41-55 15 p.

研究成果: ジャーナルへの寄稿記事

Hepatocytes
Stem Cells
Liver
Liver Regeneration
Regenerative Medicine
4 引用 (Scopus)

Co-regulation of Cxcl1 and versican in the inflammatory response to UVB induced reactive oxygen species in skin photo-tumorigenesis

Takemori, C., Kunisada, M., Yogianti, F., Oka, S., Sakumi, K., Ono, R., Nakabeppu, Y. & Nishigori, C., 2 1 2017, : : Journal of Dermatological Science. 85, 2, p. 140-143 4 p.

研究成果: ジャーナルへの寄稿レター

Neoplastic Gene Expression Regulation
Chemokine CXCL1
Radiation-Induced Neoplasms
Versicans
DNA Glycosylases

Correction: Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse [The Journal of Experimental Medicine, 210, 12, November 18, (2013) 2721-2737]doi 10.1084/jem.20131324

Le Floc'h, A., Tanaka, Y., Bantilan, N. S., Voisinne, G., Altan-Bonnet, G., Fukui, Y. & Huse, M., 4 1 2017, : : Journal of Experimental Medicine. 214, 4, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Immunological Synapses
Biomedical Research
Actins
Emotions
5 引用 (Scopus)

Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8

Taguchi, H., Xie, Y., Horikoshi, N., Maehara, K., Harada, A., Nogami, J., Sato, K., Arimura, Y., Osakabe, A., Kujirai, T., Iwasaki, T., Semba, Y., Tachibana, T., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 25 2017, : : Biochemistry. 56, 16, p. 2184-2196 13 p.

研究成果: ジャーナルへの寄稿記事

Nucleosomes
Histones
Crystal structure
Epigenomics
Thermodynamic stability
26 引用 (Scopus)

Crystal structure of the overlapping dinucleosome composed of hexasome and octasome

Kato, D., Osakabe, A., Arimura, Y., Mizukami, Y., Horikoshi, N., Saikusa, K., Akashi, S., Nishimura, Y., Park, S. Y., Nogami, J., Maehara, K., Ohkawa, Y., Matsumoto, A., Kono, H., Inoue, R., Sugiyama, M. & Kurumizaka, H., 4 14 2017, : : Science. 356, 6334, p. 205-208 4 p., 356.

研究成果: ジャーナルへの寄稿記事

Nucleosomes
Chromatin Assembly and Disassembly
Histones
DNA
Base Pairing
5 引用 (Scopus)

C-type lectin receptor Dectin-2 binds to an endogenous protein β-glucuronidase on dendritic cells

Mori, D., Shibata, K. & Yamasaki, S., 1 2017, : : PloS one. 12, 1, e0169562.

研究成果: ジャーナルへの寄稿記事

C-Type Lectins
Glucuronidase
dendritic cells
mannose
lectins
11 引用 (Scopus)

C-type lectin receptors in anti-fungal immunity

Shiokawa, M., Yamasaki, S. & Saijo, S., 12 1 2017, : : Current Opinion in Microbiology. 40, p. 123-130 8 p.

研究成果: ジャーナルへの寄稿評論記事

C-Type Lectins
Immunity
Immune System
Ligands
Mycoses
4 引用 (Scopus)

Dectin-1 intracellular domain determines species-specific ligand spectrum by modulating receptor sensitivity

Takano, T., Motozono, C., Imai, T., Sonoda, K. H., Nakanishi, Y. & Yamasaki, S., 1 1 2017, : : Journal of Biological Chemistry. 292, 41, p. 16933-16941 9 p.

研究成果: ジャーナルへの寄稿記事

Ligands
Glucans
C-Type Lectins
dectin 1
Seaweed
12 引用 (Scopus)

Defects in dosage compensation impact global gene regulation in the mouse trophoblast

Sakata, Y., Nagao, K., Hoki, Y., Sasaki, H., Obuse, C. & Sado, T., 8 1 2017, : : Development (Cambridge). 144, 15, p. 2784-2797 14 p.

研究成果: ジャーナルへの寄稿記事

Trophoblasts
RNA
X Chromosome Inactivation
Genes
Alleles
5 引用 (Scopus)

Development of a split-flow system for high precision variable sample introduction in supercritical fluid chromatography

Sakai, M., Hayakawa, Y., Funada, Y., Ando, T., Fukusaki, E. & Bamba, T., 9 15 2017, : : Journal of Chromatography A. 1515, p. 218-231 14 p.

研究成果: ジャーナルへの寄稿記事

Supercritical Fluid Chromatography
Pressure drop
Pressure
Flow rate
Pressure regulators
1 引用 (Scopus)

Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells

Shishido, Y., Baba, T., Sato, T., Shima, Y., Miyabayashi, K., Inoue, M., Akiyama, H., Kimura, H., Kanai, Y., Ishihara, Y., Haraguchi, S., Miyazaki, A., Rozman, D., Yamazaki, T., Choi, M. H., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 1 1 2017, : : Scientific reports. 7, 41912.

研究成果: ジャーナルへの寄稿記事

Sertoli Cells
Lactic Acid
Cholesterol
Germ Cells
Nursing
12 引用 (Scopus)

Distinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status

Sakanaka, A., Kuboniwa, M., Hashino, E., Bamba, T., Fukusaki, E. & Amano, A., 2 21 2017, : : Scientific reports. 7, 42818.

研究成果: ジャーナルへの寄稿記事

Dental Plaque
Debridement
Dysbiosis
Metabolomics
Metabolic Diseases
5 引用 (Scopus)

DOCK8 protein regulates macrophage migration through Cdc42 protein activation and LRAP35a protein interaction

Shiraishi, A., Uruno, T., Sanematsu, F., Ushijima, M., Sakata, D., Hara, T. & Fukui, Y., 2 10 2017, : : Journal of Biological Chemistry. 292, 6, p. 2191-2202 12 p.

研究成果: ジャーナルへの寄稿記事

cdc42 GTP-Binding Protein
Macrophages
Chemical activation
Guanine Nucleotide Exchange Factors
Proteins
2 引用 (Scopus)

Effect of Furan Fatty Acids and 3-Methyl-2,4-nonanedione on Light-Induced Off-Odor in Soybean Oil

Sano, T., Okabe, R., Iwahashi, M., Imagi, J., Sato, T., Yamashita, T., Fukusaki, E. & Bamba, T., 3 15 2017, : : Journal of Agricultural and Food Chemistry. 65, 10, p. 2136-2140 5 p.

研究成果: ジャーナルへの寄稿記事

Soybean Oil
off odors
furans
Odors
soybean oil

Erratum: Structure and function of human histone H3.Y nucleosome (Nucleic acids research (2016) 44 13 (6127-6141))

Kujirai, T., Horikoshi, N., Sato, K., Maehara, K., Machida, S., Osakabe, A., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 7 2017, : : Nucleic acids research. 45, 6, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Nucleosomes
Histones
Nucleic Acids
Research
8 引用 (Scopus)

Essential role of FBXL5-mediated cellular iron homeostasis in maintenance of hematopoietic stem cells

Muto, Y., Nishiyama, M., Nita, A., Moroishi, T. & Nakayama, K. I., 7 17 2017, : : Nature communications. 8, 16114.

研究成果: ジャーナルへの寄稿記事

homeostasis
stem cells
Hematopoietic Stem Cells
Stem cells
maintenance
5 引用 (Scopus)

Evolution of the sperm methylome of primates is associated with retrotransposon insertions and genome instability

Fukuda, K., Inoguchi, Y., Ichiyanagi, K., Ichiyanagi, T., Go, Y., Nagano, M., Yanagawa, Y., Takaesu, N., Ohkawa, Y., Imai, H. & Sasaki, H., 9 1 2017, : : Human Molecular Genetics. 26, 18, p. 3508-3519 12 p.

研究成果: ジャーナルへの寄稿記事

Retroelements
Genomic Instability
Primates
Spermatozoa
Pan troglodytes
3 引用 (Scopus)

Facultative parthenogenesis validated by DNA analyses in the green anaconda (Eunectes murinus)

Shibata, H., Sakata, S., Hirano, Y., Nitasaka, E. & Sakabe, A., 12 2017, : : PloS one. 12, 12, e0189654.

研究成果: ジャーナルへの寄稿記事

Parthenogenesis
Boidae
parthenogenesis
Clutches
Microsatellite Repeats
6 引用 (Scopus)

FBXL5 inactivation in mouse brain induces aberrant proliferation of neural stem progenitor cells

Yamauchi, T., Nishiyama, M., Moroishi, T., Kawamura, A. & Nakayama, K. I., 4 1 2017, : : Molecular and cellular biology. 37, 8, e00470-16.

研究成果: ジャーナルへの寄稿記事

Neural Stem Cells
Stem Cells
Iron
Iron Regulatory Protein 2
Brain
4 引用 (Scopus)

Fenton reaction-induced renal carcinogenesis in Mutyh-deficient mice exhibits less chromosomal aberrations than the rat model

Li, G. H., Akatsuka, S., Chew, S. H., Jiang, L., Nishiyama, T., Sakamoto, A., Takahashi, T., Futakuchi, M., Suzuki, H., Kunihiko, S., Nakabeppu, Y. & Toyokuni, S., 11 1 2017, : : Pathology International. 67, 11, p. 564-574 11 p.

研究成果: ジャーナルへの寄稿記事

Chromosome Aberrations
Carcinogenesis
Kidney
Genotype
Methylation
10 引用 (Scopus)

Generation of Mouse and Human Organoid-Forming Intestinal Progenitor Cells by Direct Lineage Reprogramming

Miura, S. & Suzuki, A., 10 5 2017, : : Cell stem cell. 21, 4, p. 456-471.e5

研究成果: ジャーナルへの寄稿記事

Organoids
Cell Lineage
Stem Cells
Intestines
Transcription Factors
1 引用 (Scopus)

Genome-wide DNA methylation analysis reveals hypomethylation in the low-CpG promoter regions in lymphoblastoid cell lines

Taniguchi, I., Iwaya, C., Ohnaka, K., Shibata, H. & Yamamoto, K., 3 4 2017, : : Human Genomics. 11, 1, 8.

研究成果: ジャーナルへの寄稿記事

DNA Methylation
Genetic Promoter Regions
Methylation
Genome
Blood Cells
11 引用 (Scopus)

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kayama, K., Watanabe, S., Takafuji, T., Tsuji, T., Hironaka, K., Matsumoto, M., Nakayama, K. I., Enari, M., Kohno, T., Shiraishi, K., Kiyono, T., Yoshida, K., Sugimoto, N. & Fujita, M., 1 1 2017, : : EMBO Reports. 18, 1, p. 123-137 15 p.

研究成果: ジャーナルへの寄稿記事

Glutamic Acid
Carcinogenesis
Ligases
Ubiquitin
WD40 Repeats
36 引用 (Scopus)

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes

Nakayama, A., Nakaoka, H., Yamamoto, K., Sakiyama, M., Shaukat, A., Toyoda, Y., Okada, Y., Kamatani, Y., Nakamura, T., Takada, T., Inoue, K., Yasujima, T., Yuasa, H., Shirahama, Y., Nakashima, H., Shimizu, S., Higashino, T., Kawamura, Y., Ogata, H., Kawaguchi, M. および26人, Ohkawa, Y., Danjoh, I., Tokumasu, A., Ooyama, K., Ito, T., Kondo, T., Wakai, K., Stiburkova, B., Pavelka, K., Stamp, L. K., Dalbeth, N., Sakurai, Y., Suzuki, H., Hosoyamada, M., Fujimori, S., Yokoo, T., Hosoya, T., Inoue, I., Takahashi, A., Kubo, M., Ooyama, H., Shimizu, T., Ichida, K., Shinomiya, N., Merriman, T. R. & Matsuo, H., 5 1 2017, : : Annals of the Rheumatic Diseases. 76, 5, p. 869-877 9 p.

研究成果: ジャーナルへの寄稿記事

Gout
Genome-Wide Association Study
Genes
Uric Acid
Functional analysis
79 引用 (Scopus)

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in frozen human plasma

Bowden, J. A., Heckert, A., Ulmer, C. Z., Jones, C. M., Koelmel, J. P., Abdullah, L., Ahonen, L., Alnouti, Y., Armando, A. M., Asara, J. M., Bamba, T., Barr, J. R., Bergquist, J., Borchers, C. H., Brandsma, J., Breitkopf, S. B., Cajka, T., Cazenave-Gassiot, A., Checa, A., Cinel, M. A. および74人, Colas, R. A., Cremers, S., Dennis, E. A., Evans, J. E., Fauland, A., Fiehn, O., Gardner, M. S., Garrett, T. J., Gotlinger, K. H., Han, J., Huang, Y., Neo, A. H., Hyötyläinen, T., Izumi, Y., Jiang, H., Jiang, H., Jiang, J., Kachman, M., Kiyonami, R., Klavins, K., Klose, C., Köfeler, H. C., Kolmert, J., Koal, T., Koster, G., Kuklenyik, Z., Kurland, I. J., Leadley, M., Lin, K., Maddipati, K. R., McDougall, D., Meikle, P. J., Mellett, N. A., Monnin, C., Moseley, M. A., Nandakumar, R., Oresic, M., Patterson, R., Peake, D., Pierce, J. S., Post, M., Postle, A. D., Pugh, R., Qiu, Y., Quehenberger, O., Ramrup, P., Rees, J., Rembiesa, B., Reynaud, D., Roth, M. R., Sales, S., Schuhmann, K., Schwartzman, M. L., Serhan, C. N., Shevchenko, A., Somerville, S. E., St John-Williams, L., Surma, M. A., Takeda, H., Thakare, R., Thompson, J. W., Torta, F., Triebl, A., Trötzmüller, M., Ubhayasekera, S. J. K., Vuckovic, D., Weir, J. M., Welti, R., Wenk, M. R., Wheelock, C. E., Yao, L., Yuan, M., Zhao, X. H. & Zhou, S., 1 1 2017, : : Journal of Lipid Research. 58, 12, p. 2275-2288 14 p.

研究成果: ジャーナルへの寄稿記事

Plasma (human)
Metabolites
Lipids
Workflow
Consensus
13 引用 (Scopus)

Heat shock protein 70 inhibitors suppress androgen receptor expression in LNCaP95 prostate cancer cells

Kita, K., Shiota, M., Tanaka, M., Otsuka, A., Matsumoto, M., Kato, M., Tamada, S., Iwao, H., Miura, K., Nakatani, T. & Tomita, S., 9 2017, : : Cancer Science. 108, 9, p. 1820-1827 8 p.

研究成果: ジャーナルへの寄稿記事

HSP70 Heat-Shock Proteins
Androgen Receptors
Prostatic Neoplasms
Castration
Quercetin
52 引用 (Scopus)

Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis

Kim, W., Khan, S. K., Gvozdenovic-Jeremic, J., Kim, Y., Dahlman, J., Kim, H., Park, O., Ishitani, T., Jho, E. H., Gao, B. & Yang, Y., 1 3 2017, : : Journal of Clinical Investigation. 127, 1, p. 137-152 16 p.

研究成果: ジャーナルへの寄稿記事

Catenins
Hepatocellular Carcinoma
Carcinogenesis
Liver
Neoplasms