生体分子情報学

研究成果 1992 2019

2004
291 引用 (Scopus)
Artificial Receptors
Molecular recognition
Titration
Peptides
Zinc
165 引用 (Scopus)

Molecular recognition in a supramolecular hydrogel to afford a semi-wet sensor chip

Yoshimura, I., Miyahara, Y., Kasagi, N., Yamane, H., Ojida, A. & Hamachi, I., 10 6 2004, : : Journal of the American Chemical Society. 126, 39, p. 12204-12205 2 p.

研究成果: ジャーナルへの寄稿記事

Molecular recognition
Hydrogel
Hydrogels
Sensors
Immobilization
10 引用 (Scopus)

Novel stable fluorophore, 6-methoxy-4-quinolone, with strong fluorescence in wide pH range of aqueous media, and its application as a fluorescent labeling reagent

Hirano, J., Hamase, K., Fukuda, H., Tomita, T. & Zaitsu, K., 12 3 2004, : : Journal of Chromatography A. 1059, 1-2, p. 225-231 7 p.

研究成果: ジャーナルへの寄稿記事

Fluorophores
Labeling
Fluorescence
Wavelength
Quantum yield
31 引用 (Scopus)

Phosphoprotein-selective recognition and staining in SDS-PAGE by bis-Zn(II)-dipycolylamine-appended anthracene

Ojida, A., Kohira, T. & Hamachi, I., 8 5 2004, : : Chemistry Letters. 33, 8, p. 1024-1025 2 p.

研究成果: ジャーナルへの寄稿記事

Phosphoproteins
Electrophoresis
Fluorescent Dyes
Gels
Fluorescence
30 引用 (Scopus)

Recognition and Fluorescence Sensing of Specific Amino Acid Residue on Protein Surface Using Designed Molecules

Ojida, A., Miyahara, Y., Kohira, T. & Hamachi, I., 5 6 2004, : : Biopolymers - Peptide Science Section. 76, 2, p. 177-184 8 p.

研究成果: ジャーナルへの寄稿記事

Amino acids
Membrane Proteins
Fluorescence
Proteins
Amino Acids
6 引用 (Scopus)

Stereocontrolled synthesis of (1S)-1-(1H-imidazol-4-yl)-1-(6-methoxy-2- naphthyl)-2-methylpropan-1-ol as a potent C17,20-lyase inhibitor

Ojida, A., Matsunaga, N., Kaku, T. & Tasaka, A., 5 24 2004, : : Tetrahedron Asymmetry. 15, 10, p. 1555-1559 5 p.

研究成果: ジャーナルへの寄稿記事

Lyases
imidazoles
inhibitors
Grignard reactions
Propanol
6 引用 (Scopus)

Synthesis of 61-bis(1-adamantylcarbamoyl)-1,2-methano[60]fullerene and its antagonistic effect on haloperidol-induced catalepsy in mice

Nakazono, M., Hasegawa, S., Yamamoto, T. & Zaitsu, K., 11 15 2004, : : Bioorganic and Medicinal Chemistry Letters. 14, 22, p. 5619-5621 3 p.

研究成果: ジャーナルへの寄稿記事

Fullerenes
Catalepsy
Haloperidol
Derivatives
61-bis(1-adamantylcarbamoyl)-1,2-methano(60)fullerene
5 引用 (Scopus)

Synthesis of photosensitive luminol releasing compound, luminol-O-2-nitrobenzylate

Nakazono, M., Asechi, M. & Zaitsu, K., 4 15 2004, : : Journal of Photochemistry and Photobiology A: Chemistry. 163, 1-2, p. 149-152 4 p.

研究成果: ジャーナルへの寄稿記事

Luminol
releasing
synthesis
proportion
Irradiation
16 引用 (Scopus)

Synthetic studies on (1S)-1-(6,7-dimethoxy-2-naphthyl)-1-(1H-imidazol-4-yl) -2-methylpropan-1-ol as a selective C17,20-lyase inhibitor

Matsunaga, N., Kaku, T., Ojida, A. & Tasaka, A., 7 5 2004, : : Tetrahedron Asymmetry. 15, 13, p. 2021-2028 8 p.

研究成果: ジャーナルへの寄稿記事

Grignard reactions
Lyases
Ketones
imidazoles
ketones
2003
12 引用 (Scopus)

2-Amino-3-phenylpyrazine, a sensitive fluorescence prelabeling reagent for the chromatographic or electrophoretic determination of saccharides

Yamamoto, K., Hamase, K. & Zaitsu, K., 7 4 2003, : : Journal of Chromatography A. 1004, 1-2, p. 99-106 8 p.

研究成果: ジャーナルへの寄稿記事

Monosaccharides
Fluorescence
Fetuins
Labeling
Calibration
7 引用 (Scopus)

Application of in vivo ESR spectroscopy to pharmaceutical sciences: Evaluation of in vivo inhibitory mechanism of antigastric lesion drugs

Kasazaki, K., Yasukawa, K., Sano, H., Yamada, K-I. & Utsumi, H., 1 1 2003, : : Applied Magnetic Resonance. 23, 3-4, p. 585-595 11 p.

研究成果: ジャーナルへの寄稿記事

lesions
electron paramagnetic resonance
drugs
evaluation
spectroscopy
24 引用 (Scopus)

Association between the expression of inducible nitric oxide synthase by chondrocytes and its nitric oxide-generating activity in adjuvant arthritis in rats

Yonekura, Y., Koshiishi, I., Yamada, K-I., Mori, A., Uchida, S., Nakamura, T. & Utsumi, H., 1 1 2003, : : Nitric Oxide - Biology and Chemistry. 8, 3, p. 164-169 6 p.

研究成果: ジャーナルへの寄稿記事

Experimental Arthritis
Nitric Oxide Synthase Type II
Chondrocytes
Rats
Nitric Oxide
100 引用 (Scopus)

Cross-linking strategy for molecular recognition and fluorescent sensing of a multi-phosphorylated peptide in aqueous solution

Ojida, A., Inoue, M. A., Mito-oka, Y. & Hamachi, I., 8 27 2003, : : Journal of the American Chemical Society. 125, 34, p. 10184-10185 2 p.

研究成果: ジャーナルへの寄稿記事

Molecular recognition
Peptides
Membrane Proteins
Artificial Receptors
Proteins
80 引用 (Scopus)

Determination of D-alanine in the rat central nervous system and periphery using column-switching high-performance liquid chromatography

Morikawa, A., Hamase, K. & Zaitsu, K., 1 1 2003, : : Analytical Biochemistry. 312, 1, p. 66-72 7 p.

研究成果: ジャーナルへの寄稿記事

High performance liquid chromatography
Neurology
Alanine
Rats
Central Nervous System
22 引用 (Scopus)

Determination of endogenous melatonin in the individual pineal glands of inbred mice using precolumn oxidation reversed-phase micro-high-performance liquid chromatography

Tomita, T., Hamase, K., Hayashi, H., Fukuda, H., Hirano, J. & Zaitsu, K., 5 15 2003, : : Analytical Biochemistry. 316, 2, p. 154-161 8 p.

研究成果: ジャーナルへの寄稿記事

Pineal Gland
High performance liquid chromatography
Melatonin
High Pressure Liquid Chromatography
Oxidation
4 引用 (Scopus)
Ethyldimethylaminopropyl Carbodiimide
Dendrimers
Chemiluminescence
Cationic surfactants
Luminescence
53 引用 (Scopus)
Electron Spin Resonance Spectroscopy
Free Radicals
Tomography
Paramagnetic resonance
Wounds and Injuries
8 引用 (Scopus)

Lasting chemiluminescence of 3-indoleglyoxylyl chloride and its enhancement

Nakazono, M., Sho, Y. & Zaitsu, K., 1 1 2003, : : Analytical Sciences. 19, 1, p. 123-127 5 p.

研究成果: ジャーナルへの寄稿記事

Chemiluminescence
Chlorides
Skatole
Cyclodextrins
Bovine Serum Albumin
2002
27 引用 (Scopus)

Constituents of holothuroidea, 12. Isolation and structure of glucocerebrosides from the sea cucumber Holothuria pervicax

Yamada, K., Tabata, K., Harada, Y., Isobe, R. & Higuchi, R., 11 1 2002, : : Chemical and Pharmaceutical Bulletin. 50, 11, p. 1467-1470 4 p.

研究成果: ジャーナルへの寄稿記事

Holothuria
Sea Cucumbers
Glucosylceramides
Recycling
Chloroform
150 引用 (Scopus)

D-amino acids in mammals and their diagnostic value

Hamase, K., Morikawa, A. & Zaitsu, K., 12 5 2002, : : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 781, 1-2, p. 73-91 19 p.

研究成果: ジャーナルへの寄稿評論記事

Mammals
Amino Acids
Tissue
Tissue Distribution
5 引用 (Scopus)

Determination of polyphenols with HPLC-sensitized chemiluminescence

Ma, L., Nakazono, M., Ohba, Y. & Zaitsu, K., 10 1 2002, : : analytical sciences. 18, 10, p. 1163-1165 3 p.

研究成果: ジャーナルへの寄稿記事

Chemiluminescence
Polyphenols
Luminescence
High Pressure Liquid Chromatography
101 引用 (Scopus)

Efficient fluorescent ATP-sensing based on coordination chemistry under aqueous neutral conditions

Ojida, A., Park, S. K., Mito-Oka, Y. & Hamachi, I., 8 26 2002, : : Tetrahedron Letters. 43, 35, p. 6193-6195 3 p.

研究成果: ジャーナルへの寄稿記事

Adenosine Triphosphate
bis-dipicolylamine-Zinc(II)
anthracene
6 引用 (Scopus)

Evaluation of a high-speed signal-averager for sensitivity enhancement in radio frequency Fourier transform electron paramagnetic resonance imaging

Devasahayam, N., Murugesan, R., Yamada, K-I., Reijnders, K., Mitchell, J. B., Subramanian, S., Krishna, M. C. & Cook, J. A., 11 1 2002, : : Review of Scientific Instruments. 73, 11, 1 p.

研究成果: ジャーナルへの寄稿記事

Paramagnetic resonance
radio frequencies
electron paramagnetic resonance
Fourier transforms
high speed
303 引用 (Scopus)

First artificial receptors and chemosensors toward phosphorylated peptide in aqueous solution

Ojida, A., Mito-Oka, Y., Inoue, M. A. & Hamachi, I., 6 5 2002, : : Journal of the American Chemical Society. 124, 22, p. 6256-6258 3 p.

研究成果: ジャーナルへの寄稿記事

Artificial Receptors
Peptides
Anthracene
Zinc
Fluorescence
18 引用 (Scopus)

Fluorine electron double resonance imaging for 19F MRI in low magnetic fields

Murugesan, R., English, S., Reijnders, K., Yamada, K-I., Cook, J. A., Mitchell, J. B., Subramanian, S. & Krishna, M. C., 9 1 2002, : : Magnetic Resonance in Medicine. 48, 3, p. 523-529 7 p.

研究成果: ジャーナルへの寄稿記事

Fluorine
Magnetic Fields
Electrons
Protons
Contrast Media
43 引用 (Scopus)

Highly Enantioselective Reformatsky Reaction of Ketones: Chelation-Assisted Enantioface Discrimination

Ojida, A., Yamano, T., Taya, N. & Tasaka, A., 9 5 2002, : : Organic Letters. 4, 18, p. 3051-3054 4 p.

研究成果: ジャーナルへの寄稿記事

Cinchona Alkaloids
chelation
alkaloids
Enantioselectivity
Chelation
43 引用 (Scopus)

Noninvasive in vivo oximetric imaging by radiofrequency FT EPR

Subramanian, S., Yamada, K-I., Irie, A., Murugesan, R., Cook, J. A., Devasahayam, N., Van Dam, G. M., Mitchell, J. B. & Krishna, M. C., 5 9 2002, : : Magnetic Resonance in Medicine. 47, 5, p. 1001-1008 8 p.

研究成果: ジャーナルへの寄稿記事

Electron Spin Resonance Spectroscopy
Oxygen
Oximetry
Neoplasms
Inbred C3H Mouse
2 引用 (Scopus)
Labeling
Fluorescence
Regeneration
Muramidase
Proteins
23 引用 (Scopus)

Synthesis of poly (3,4,5-trihydroxybenzoate ester) dendrimers and their chemiluminescence

Nakazono, M., Ma, L. & Zaitsu, K., 11 4 2002, : : Tetrahedron Letters. 43, 45, p. 8185-8189 5 p.

研究成果: ジャーナルへの寄稿記事

Dendrimers
Chemiluminescence
Luminescence
Gallic Acid
Esters
2001
117 引用 (Scopus)

Determination of free D-aspartic acid, D-serine and D-alanine in the brain of mutant mice lacking D-amino-acid oxidase activity

Morikawa, A., Hamase, K., Inoue, T., Konno, R., Niwa, A. & Zaitsu, K., 6 5 2001, : : Journal of Chromatography B: Biomedical Sciences and Applications. 757, 1, p. 119-125 7 p.

研究成果: ジャーナルへの寄稿記事

D-Amino-Acid Oxidase
D-Aspartic Acid
Alanine
Serine
Brain
63 引用 (Scopus)

Determination of free D-proline and D-leucine in the brains of mutant mice lacking D-amino acid oxidase activity

Hamase, K., Inoue, T., Morikawa, A., Konno, R. & Zaitsu, K., 12 15 2001, : : Analytical Biochemistry. 298, 2, p. 253-258 6 p.

研究成果: ジャーナルへの寄稿記事

D-Amino-Acid Oxidase
Proline
Leucine
Brain
Pineal Gland
116 引用 (Scopus)

Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion

Miranda, K. M., Espey, M. G., Yamada, K-I., Krishna, M., Ludwick, N., Kim, S., Jourd'heuil, D., Grisham, M. B., Feelisch, M., Fukuto, J. M. & Wink, D. A., 1 19 2001, : : Journal of Biological Chemistry. 276, 3, p. 1720-1727 8 p.

研究成果: ジャーナルへの寄稿記事

Nitrosation
Reactive Nitrogen Species
Peroxynitrous Acid
Benzoic Acid
Azides
2000
45 引用 (Scopus)
Enantiomers
High performance liquid chromatography
Leucine
Rats
Brain
25 引用 (Scopus)
High performance liquid chromatography
Reverse-Phase Chromatography
Melatonin
Circadian Rhythm
Rats
5 引用 (Scopus)

Flow injection analysis for pyrogallol using 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide as polyphenol chemiluminescence enhancer

Ohba, Y., Yamashita, M., Nakazono, M., Ma, L. & Zaitsu, K., 1 1 2000, : : analytical sciences. 16, 9, p. 979-980 2 p.

研究成果: ジャーナルへの寄稿記事

Ethyldimethylaminopropyl Carbodiimide
Pyrogallol
Chemiluminescence
Polyphenols
33 引用 (Scopus)

Molecular characterization of a novel β-glucuronidase from Scutellaria baicalensis Georgi

Tabata, K., Taura, F., Shoyama, Y. & Morimoto, S., 9 1 2000, : : Journal of Biological Chemistry. 275, 35, p. 27466-27472 7 p.

研究成果: ジャーナルへの寄稿記事

Scutellaria baicalensis
Glucuronidase
Scutellaria
Mutagenesis
Site-Directed Mutagenesis
5 引用 (Scopus)

Non-acidic matrix for the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of acid-labile compounds

Ohba, Y., Koto, N., Hamase, K. & Zaitsu, K., 1 1 2000, : : analytical sciences. 16, 6, p. 659-661 3 p.

研究成果: ジャーナルへの寄稿コメント/討論

Ionization
Mass spectrometry
Desorption
Acids
Lasers
15 引用 (Scopus)

Reversed-phase HPLC of monosaccharides in glycoproteins derivatized with aminopyrazine with fluorescence detection

Wu, W., Hamase, K., Kiguchi, M., Yamamoto, K. & Zaitsu, K., 1 1 2000, : : analytical sciences. 16, 9, p. 919-922 4 p.

研究成果: ジャーナルへの寄稿記事

Monosaccharides
Glycoproteins
Fluorescence
Anions
Derivatives
2 引用 (Scopus)

Selective masking of amino groups during fluorescence derivatization in the presence of a molecular imprint polymer

Hamase, K., Iwashita, K. & Zaitsu, K., 1 1 2000, : : analytical sciences. 16, 4, p. 417-419 3 p.

研究成果: ジャーナルへの寄稿記事

Polymers
Fluorescence
1999
10 引用 (Scopus)

Alteration in the D-amino acid content of the rat pineal gland under anesthesia

Hamase, K., Homma, H., Takigawa, Y. & Imai, K., 1 1 1999, : : Amino Acids. 17, 3, p. 277-283 7 p.

研究成果: ジャーナルへの寄稿記事

Pineal Gland
Urethane
Rats
Anesthesia
Amino Acids
2 引用 (Scopus)

Chemiluminescence of polyhydroxyphenol linked-calix[4]arenes

Nakazono, M., Ohba, Y. & Zaitsu, K., 1 1 1999, : : Chemical and Pharmaceutical Bulletin. 47, 4, p. 569-570 2 p.

研究成果: ジャーナルへの寄稿記事

Chemiluminescence
Luminescence
Pyrogallol
Gallic Acid
Hydrogen Peroxide
8 引用 (Scopus)

Enantio-selective derivatization of amino compounds in the presence of a molecular imprint polymer

Hamase, K., Iwashita, K. & Zaitsu, K., 1 1 1999, : : analytical sciences. 15, 5, p. 411-412 2 p.

研究成果: ジャーナルへの寄稿記事

Enantiomers
Polymers
Amino Acids
9 引用 (Scopus)

Heme-undecapeptide labeling on insulin for the immunoassay of insulin with chemiluminescence detection

Zaitsu, K., Kimura, Y., Ohba, Y., Hamase, K., Motomura, Y., Itose, M. & Ishiyama, M., 1 1 1999, : : Analytical Sciences. 15, 9, p. 871-878 8 p.

研究成果: ジャーナルへの寄稿記事

Chemiluminescence
Heme
Labeling
Insulin
Insulins
1 引用 (Scopus)

Reversible fluorescence derivatization of amino groups using dansylaminomethylmaleic acid via its anhydride

Sakata, K., Hamase, K., Sasaki, S., Maeda, M. & Zaitsu, K., 1 1 1999, : : analytical sciences. 15, 11, p. 1095-1099 5 p.

研究成果: ジャーナルへの寄稿記事

Anhydrides
Fluorescence
Acids
Insulin
Labeling
7 引用 (Scopus)

Sensitive anion-exchange HPLC of aminopyrazine derivatives of saccharides having N-acetylated monosaccharide at the reducing end

Kiguchi, M., Hamase, K., Wu, W., Yamamoto, K. & Zaitsu, K., 1 1 1999, : : analytical sciences. 15, 9, p. 903-905 3 p.

研究成果: ジャーナルへの寄稿コメント/討論

Monosaccharides
Anions
Carbohydrates
Derivatives
32 引用 (Scopus)

Sensitive determination of melatonin by precolumn derivatization and reversed-phase high-performance liquid chromatography

Iinuma, F., Hamase, K., Matsubayashi, S., Takahashi, M., Watanabe, M. & Zaitsu, K., 3 12 1999, : : Journal of Chromatography A. 835, 1-2, p. 67-72 6 p.

研究成果: ジャーナルへの寄稿記事

High performance liquid chromatography
Reverse-Phase Chromatography
Melatonin
High Pressure Liquid Chromatography
Derivatives
24 引用 (Scopus)

Simple and rapid analytical method for carbapenems using capillary zone electrophoresis

Taniguchi, S., Hamase, K., Kinoshita, A. & Zaitsu, K., 4 30 1999, : : Journal of Chromatography B: Biomedical Sciences and Applications. 727, 1-2, p. 219-225 7 p.

研究成果: ジャーナルへの寄稿記事

Carbapenems
Electrophoresis
Capillary electrophoresis
meropenem
Buffers
1998
6 引用 (Scopus)

Chemiluminescence Enhancer of Polyphenols, 1-Ethy1-3-(3-dimethylaminopropyl)carbodiimide

Nakazono, M., Ijichi, J., Ohba, Y. & Zaitsu, K., 1 1 1998, : : analytical sciences. 14, 4, p. 853-854 2 p.

研究成果: ジャーナルへの寄稿記事

Ethyldimethylaminopropyl Carbodiimide
Carbodiimides
Chemiluminescence
Polyphenols
1997
27 引用 (Scopus)
Boron compounds
Magnetic materials
Nitrogen oxides
Carboxylic acids
Molecular structure
106 引用 (Scopus)

Membrane permeabilization mechanisms of a cyclic antimicrobial peptide, Tachyplesin I, and its linear analog

Matsuzaki, K., Yoneyama, S., Fujii, N., Miyajima, K., Yamada, K-I., Kirino, Y. & Anzai, K., 8 12 1997, : : Biochemistry. 36, 32, p. 9799-9806 8 p.

研究成果: ジャーナルへの寄稿記事

Cyclic Peptides
Membranes
Peptides
Lipids
Artificial Membranes