研究成果 1982 2019

フィルター
記事
2019

RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121

Sekiguchi, T., Furuno, N., Ishii, T., Hirose, E., Sekiguchi, F., Wang, Y. & Kobayashi, H., 2 1 2019, : : Genes to Cells. 24, 2, p. 151-161 11 p.

研究成果: ジャーナルへの寄稿記事

Hedgehog Proteins
ras Proteins
Monomeric GTP-Binding Proteins
S 6
Inborn Genetic Diseases
2018
7 引用 (Scopus)

Specific binding of PCBP1 to heavily oxidized RNA to induce cell death

Ishii, T., Hayakawa, H., Igawa, T., Sekiguchi, T. & Sekiguchi, M., 6 26 2018, : : Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. 6715-6720 6 p.

研究成果: ジャーナルへの寄稿記事

Oligoribonucleotides
Cell Death
RNA
Clustered Regularly Interspaced Short Palindromic Repeats
Poly C
2015
1 引用 (Scopus)

Phylogenetic relationships of the malay peninsula otters (Lutra sumatrana, lutrogale perspicillata, and aonyx cinereus) based on dna sequences of mitochondrial d-loop region

Rosli, M. K., Abdul-Patah, P., Syed-Shabthar, S. M. F., Burhanuddin, M. N., Sekiguchi, T., Sasaki, H., Shukor, M. N., Yaakop, S. & Md-Zain, B. M., 6 1 2015, : : Journal of Animal and Plant Sciences. 25, 3, p. 836-843 8 p.

研究成果: ジャーナルへの寄稿記事

Lutra
topology
Malaysia
genetic distance
nucleotide sequences
8 引用 (Scopus)

Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells

Ishii, T., Hayakawa, H., Sekiguchi, T., Adachi, N. & Sekiguchi, M., 2 2015, : : Free Radical Biology and Medicine. 79, p. 109-116 8 p.

研究成果: ジャーナルへの寄稿記事

Cells
RNA
Messenger RNA
Gene expression
Oxidative stress
2014
9 引用 (Scopus)

Amino acid residues required for Gtr1p-Gtr2p complex formation and its interactions with the Ego1p-Ego3p complex and TORC1 components in yeast

Sekiguchi, T., Kamada, Y., Furuno, N., Funakoshi, M. & Kobayashi, H., 6 2014, : : Genes to Cells. 19, 6, p. 449-463 15 p.

研究成果: ジャーナルへの寄稿記事

Yeasts
Amino Acids
Guanosine Triphosphate
ras Proteins
Two-Hybrid System Techniques
17 引用 (Scopus)

A new subspecies identification and population study of the Asian small-clawed otter (Aonyx cinereus) in Malay Peninsula and southern Thailand based on fecal DNA method

Rosli, M. K. A., Syed-Shabthar, S. M. F., Abdul-Patah, P., Abdul-Samad, Z., Abdul, S. N., Burhanuddin, M. N., Zulkifli, N. A., Shukor, M. N., Budsabong, K., Changtragoon, S., Sekiguchi, T., Sasaki, H. & Md-Zain, B. M., 2014, : : The Scientific World Journal. 2014, 457350.

研究成果: ジャーナルへの寄稿記事

Otters
Malaysia
Thailand
subspecies
Coastal zones
1 引用 (Scopus)

Food habits of the urban Japanese weasels mustela itatsi revealed by faecal DNA analysis

Okawara, Y., Sekiguchi, T., Ikeda, A., Miura, S., Sasaki, H., Fujii, T. & Kaneko, Y., 9 1 2014, : : Mammal Study. 39, 3, p. 155-161 7 p.

研究成果: ジャーナルへの寄稿記事

2013
11 引用 (Scopus)

Elimination and utilization of oxidized guanine nucleotides in the synthesis of RNA and its precursors

Sekiguchi, T., Ito, R., Hayakawa, H. & Sekiguchi, M., 3 22 2013, : : Journal of Biological Chemistry. 288, 12, p. 8128-8135 8 p.

研究成果: ジャーナルへの寄稿記事

Guanine Nucleotides
RNA Precursors
Guanosine Triphosphate
Nucleoside-Diphosphate Kinase
Oxidation
12 引用 (Scopus)

Mitotic phosphorylation of VCIP135 blocks p97ATPase-mediated Golgi membrane fusion

Totsukawa, G., Matsuo, A., Kubota, A., Taguchi, Y. & Kondo, H., 4 2013, : : Biochemical and Biophysical Research Communications. 433, 2, p. 237-242 6 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Membrane Fusion
Fusion reactions
Serine
Threonine
7 引用 (Scopus)

Search for proteins required for accurate gene expression under oxidative stress: Roles of Guanylate Kinase and RNA Polymerase

Inokuchi, H., Ito, R., Sekiguchi, T. & Sekiguchi, M., 11 15 2013, : : Journal of Biological Chemistry. 288, 46, p. 32952-32962 11 p.

研究成果: ジャーナルへの寄稿記事

Guanylate Kinases
Oxidative stress
DNA-Directed RNA Polymerases
Gene expression
Oxidative Stress
2011
3 引用 (Scopus)

Ubiquitin chains in the Dsk2 UBL domain mediate Dsk2 stability and protein degradation in yeast

Sekiguchi, T., Sasaki, T., Funakoshi, M., Ishii, T., Saitoh, Y. H., Kaneko, S. I. & Kobayashi, H., 8 5 2011, : : Biochemical and Biophysical Research Communications. 411, 3, p. 555-561 7 p.

研究成果: ジャーナルへの寄稿記事

Ubiquitin
Yeast
Proteolysis
Yeasts
Degradation
22 引用 (Scopus)

VCIP135 deubiquitinase and its binding protein, WAC, in p97ATPase-mediated membrane fusion

Totsukawa, G., Kaneko, Y., Uchiyama, K., Toh, H., Tamura, K. & Kondo, H., 8 31 2011, : : EMBO Journal. 30, 17, p. 3581-3593 13 p.

研究成果: ジャーナルへの寄稿記事

Membrane Fusion
Carrier Proteins
Fusion reactions
Membranes
Assays
2010
20 引用 (Scopus)

Effects of edaravone on muscle atrophy and locomotor function in patients with ischemic stroke: A randomized controlled pilot study

Naritomi, H., Moriwaki, H., Metoki, N., Nishimura, H., Higashi, Y., Yamamoto, Y., Yuasa, H., Oe, H., Tanaka, K., Saito, K., Terayama, Y., Oda, T., Tanahashi, N. & Kondo, H., 12 1 2010, : : Drugs in R and D. 10, 3, p. 155-163 9 p.

研究成果: ジャーナルへの寄稿記事

Muscular Atrophy
Atrophic Muscular Disorders
Stroke
Leg
Therapeutics
5 引用 (Scopus)

Isolation of a point-mutated p47 lacking binding affinity to p97ATPase

Kaneko, Y., Tamura, K., Totsukawa, G. & Kondo, H., 9 1 2010, : : FEBS Letters. 584, 18, p. 3873-3877 5 p.

研究成果: ジャーナルへの寄稿記事

Carrier Proteins
Mutation
Assays
Membrane Fusion
Fusion reactions
2 引用 (Scopus)

New methods for species and sex determination in three sympatric Mustelids, Mustela itatsi, Mustela sibirica and Martes melampus

Sekiguchi, T., Sasaki, H., Kurihara, Y., Watanabe, S., Moriyama, D., Kurose, N., Matsuki, R., Yamazaki, K. & Saeki, M., 11 1 2010, : : Molecular Ecology Resources. 10, 6, p. 1089-1091 3 p.

研究成果: ジャーナルへの寄稿記事

mustelid
Mustelidae
Mustela
sex determination
Martes
12 引用 (Scopus)

Phosphorylation of p37 is important for Golgi disassembly at mitosis

Kaneko, Y., Tamura, K., Totsukawa, G. & Kondo, H., 11 5 2010, : : Biochemical and Biophysical Research Communications. 402, 1, p. 37-41 5 p.

研究成果: ジャーナルへの寄稿記事

Phosphorylation
Mitosis
Serine
Membrane Fusion
Threonine
2009
8 引用 (Scopus)

Gtr1p differentially associates with Gtr2p and Ego1p

Wang, Y., Kurihara, Y., Sato, T., Toh, H., Kobayashi, H. & Sekiguchi, T., 5 15 2009, : : Gene. 437, 1-2, p. 32-38 7 p.

研究成果: ジャーナルへの寄稿記事

Caffeine
Guanine Nucleotide Exchange Factors
Monomeric GTP-Binding Proteins
Cell Nucleus Active Transport
GTP Phosphohydrolases
2 引用 (Scopus)

Ran GTPase guanine nucleotide exchange factor RCC1 is phosphorylated on serine 11 by cdc2 kinase in vitro

Horiike, Y., Kobayashi, H. & Sekiguchi, T., 4 1 2009, : : Molecular biology reports. 36, 4, p. 717-723 7 p.

研究成果: ジャーナルへの寄稿記事

Guanine Nucleotide Exchange Factors
GTP Phosphohydrolases
Serine
Phosphotransferases
Phosphorylation
2008
59 引用 (Scopus)

Analysis of nucleotide binding to P97 reveals the properties of a tandem AAA hexameric ATPase

Briggs, L. C., Baldwin, G. S., Miyata, N., Kondo, H., Zhang, X. & Freemont, P. S., 5 16 2008, : : Journal of Biological Chemistry. 283, 20, p. 13745-13752 8 p.

研究成果: ジャーナルへの寄稿記事

Adenosine Triphosphatases
Nucleotides
Adenosine Diphosphate
Endoplasmic Reticulum-Associated Degradation
Organelle Biogenesis
10 引用 (Scopus)
ras Proteins
GTP Phosphohydrolases
Epigenomics
Gene expression
Yeast
2007
21 引用 (Scopus)

Phosphorylation of threonine 204 of DEAD-box RNA helicase DDX3 by cyclin B/cdc2 in vitro

Sekiguchi, T., Kurihara, Y. & Fukumura, J., 5 11 2007, : : Biochemical and Biophysical Research Communications. 356, 3, p. 668-673 6 p.

研究成果: ジャーナルへの寄稿記事

DEAD-box RNA Helicases
Cyclin B
Phosphorylation
Threonine
Cyclin A
2006
25 引用 (Scopus)

NOP132 is required for proper nucleolus localization of DEAD-box RNA helicase DDX47

Sekiguchi, T., Hayano, T., Yanagida, M., Takahashi, N. & Nishimoto, T., 9 1 2006, : : Nucleic acids research. 34, 16, p. 4593-4608 16 p.

研究成果: ジャーナルへの寄稿記事

DEAD-box RNA Helicases
RNA Precursors
Proteins
Ribosomes
Nuclear Proteins
73 引用 (Scopus)

p37 Is a p97 Adaptor Required for Golgi and ER Biogenesis in Interphase and at the End of Mitosis

Uchiyama, K., Totsukawa, G., Puhka, M., Kaneko, Y., Jokitalo, E., Dreveny, I., Beuron, F., Zhang, X., Freemont, P. & Kondo, H., 12 1 2006, : : Developmental Cell. 11, 6, p. 803-816 14 p.

研究成果: ジャーナルへの寄稿記事

Membrane Fusion
Interphase
Mitosis
Fusion reactions
Maintenance
2005
9 引用 (Scopus)

Association of the GTP-binding protein Gtr1p with Rpc19p, a shared subunit of RNA polymerase I and III in yeast Saccharomyces cerevisiae

Todaka, Y., Wang, Y., Tashiro, K., Nakashima, N., Nishimoto, T. & Sekiguchi, T., 8 1 2005, : : Genetics. 170, 4, p. 1515-1524 10 p.

研究成果: ジャーナルへの寄稿記事

RNA Polymerase I
RNA Polymerase III
Guanosine Triphosphate
GTP-Binding Proteins
Saccharomyces cerevisiae
11 引用 (Scopus)
ran GTP-Binding Protein
Saccharomyces cerevisiae Proteins
GTP Phosphohydrolases
Cell proliferation
Yeast
2004
6 引用 (Scopus)

A Hamster Temperature-Sensitive Alanyl-tRNA Synthetase Mutant Causes Degradation of Cell-Cycle Related Proteins and Apoptosis

Wang, Y., Sekiguchi, T., Noguchi, E. & Nishimoto, T., 1 1 2004, : : Journal of Biochemistry. 135, 1, p. 7-16 10 p.

研究成果: ジャーナルへの寄稿記事

Alanine-tRNA Ligase
Cell Cycle Proteins
Cricetinae
Cells
Apoptosis
23 引用 (Scopus)

A Novel Human Nucleolar Protein, Nop132, Binds to the G Proteins, RRAG A/C/D

Sekiguchi, T., Todaka, Y., Wang, Y., Hirose, E., Nakashima, N. & Nishimoto, T., 2 27 2004, : : Journal of Biological Chemistry. 279, 9, p. 8343-8350 8 p.

研究成果: ジャーナルへの寄稿記事

Nuclear Proteins
GTP-Binding Proteins
Guanine Nucleotide Exchange Factors
Monomeric GTP-Binding Proteins
Cell growth
50 引用 (Scopus)

Human DDX3Y, the Y-encoded isoform of RNA helicase DDX3, rescues a hamster temperature-sensitive ET24 mutant cell line with a DDX3X mutation

Sekiguchi, T., Iida, H., Fukumura, J. & Nishimoto, T., 10 15 2004, : : Experimental Cell Research. 300, 1, p. 213-222 10 p.

研究成果: ジャーナルへの寄稿記事

RNA Helicases
DEAD-box RNA Helicases
Cricetinae
Protein Isoforms
Spermatogenesis
2003
35 引用 (Scopus)

A temperature-sensitive mutant of the mammalian RNA helicase, DEAD-BOX X isoform, DBX, defective in the transition from G1 to S phase

Fukumura, J., Noguchi, E., Sekiguchi, T. & Nishimoto, T., 7 1 2003, : : Journal of Biochemistry. 134, 1, p. 71-82 12 p.

研究成果: ジャーナルへの寄稿記事

RNA Helicases
S Phase
Protein Isoforms
Temperature
Cricetinae
141 引用 (Scopus)

The crystal structure of murine p97/VCP at 3.6 Å

Huyton, T., Pye, V. E., Briggs, L. C., Flynn, T. C., Beuron, F., Kondo, H., Ma, J., Zhang, X. & Freemont, P. S., 12 2003, : : Journal of structural biology. 144, 3, p. 337-348 12 p.

研究成果: ジャーナルへの寄稿記事

Membrane Fusion
Ubiquitin
Alanine
Adenosine Diphosphate
Proteolysis
79 引用 (Scopus)

The localization and phosphorylation of p47 are important for Golgi disassembly-assembly during the cell cycle

Uchiyama, K., Jokitalo, E., Lindman, M., Jackman, M., Kano, F., Murata, M., Zhang, X. & Kondo, H., 6 23 2003, : : Journal of Cell Biology. 161, 6, p. 1067-1079 13 p.

研究成果: ジャーナルへの寄稿記事

Cell Cycle
Mitosis
Phosphorylation
Membrane Fusion
Interphase
2002
162 引用 (Scopus)

VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for golgi and ER assembly in vivo

Uchiyama, K., Jokitalo, E., Kano, F., Murata, M., Zhang, X., Canas, B., Newman, R., Rabouille, C., Pappin, D., Freemont, P. & Kondo, H., 12 9 2002, : : Journal of Cell Biology. 159, 5, p. 855-866 12 p.

研究成果: ジャーナルへの寄稿記事

SNARE Proteins
Membrane Fusion
Adenosine Triphosphate
Hydrolysis
N-Ethylmaleimide-Sensitive Proteins
2001
142 引用 (Scopus)

Novel G Proteins, Rag C and Rag D, Interact with GTP-binding Proteins, Rag A and Rag B

Sekiguchi, T., Hirose, E., Nakashima, N., Ii, M. & Nishimoto, T., 3 9 2001, : : Journal of Biological Chemistry. 276, 10, p. 7246-7257 12 p.

研究成果: ジャーナルへの寄稿記事

Guanosine Triphosphate
Protein C
GTP-Binding Proteins
Yeast
Saccharomyces cerevisiae
72 引用 (Scopus)

Solution structure and interaction surface of the C-terminal domain from p47: A major p97-cofactor involved in SNARE disassembly

Yuan, X., Shaw, A., Zhang, X., Kondo, H., Lally, J., Freemont, P. S. & Matthews, S., 8 10 2001, : : Journal of Molecular Biology. 311, 2, p. 255-263 9 p.

研究成果: ジャーナルへの寄稿記事

SNARE Proteins
Membrane Fusion
Ubiquitin
Proteins
p97 ATPase
2000
18 引用 (Scopus)

Ca2+ and electrolyte mobilization following agonist application to the pancreatic β cell line HIT

Nakagaki, I., Sasaki, S., Hori, S. & Kondo, H., 1 1 2000, : : Pflugers Archiv European Journal of Physiology. 440, 6, p. 828-834 7 p.

研究成果: ジャーナルへの寄稿記事

Electrolytes
Cells
Glucose
Cell Line
Glucagon-Like Peptide 1
21 引用 (Scopus)

Inhibition of N-linked glycosylation causes apoptosis in hamster BHK21 cells

Yoshimi, M., Sekiguchi, T., Hara, N. & Nishimoto, T., 10 5 2000, : : Biochemical and Biophysical Research Communications. 276, 3, p. 965-969 5 p.

研究成果: ジャーナルへの寄稿記事

Glycosylation
Cricetinae
Tunicamycin
Apoptosis
Cells
1999
19 引用 (Scopus)

Overexpression of D-type cyclins, E2F-1, SV40 large T antigen and HPV16 E7 rescue cell cycle arrest of tsBN462 cells caused by the CCG1/TAF(II)250 mutation

Sekiguchi, T., Nishimoto, T. & Hunter, T., 3 11 1999, : : Oncogene. 18, 10, p. 1797-1806 10 p.

研究成果: ジャーナルへの寄稿記事

Cyclin D
Polyomavirus Transforming Antigens
Viral Tumor Antigens
Cyclin D1
Cell Cycle Checkpoints
1998
69 引用 (Scopus)

RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway

Hirose, E., Nakashima, N., Sekiguchi, T. & Nishimoto, T., 1998, : : Journal of Cell Science. 111, 1, p. 11-21 11 p.

研究成果: ジャーナルへの寄稿記事

GTP Phosphohydrolases
Saccharomyces cerevisiae
Complementary DNA
Cytoplasm
Mutation
1996
26 引用 (Scopus)

D-type cyclin expression is decreased and p21 and p27 CDK inhibitor expression is increased when tsBN462 CCG1/TAF11250 mutant cells arrest in G1 at the restrictive temperature

Sekiguchi, T., Noguchi, E., Hayashida, T., Nakashima, T., Toyoshima, H., Nishimoto, T. & Hunter, T., 1 1 1996, : : Genes to Cells. 1, 7, p. 687-705 19 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Cyclin D
Temperature
Cyclin A
1995
35 引用 (Scopus)

Apoptosis is induced in BHK cells by the tsBN462/13 mutation in the CCG1/TAFII250 subunit of the TFIID basal transcription factor

Sekiguchi, T., Nakashima, T., Hayashida, T., Kuraoka, A., Hashimoto, S., Tsuchida, N., Shibata, Y., Hunter, T. & Nishimoto, T., 6 1995, : : Experimental Cell Research. 218, 2, p. 490-498 9 p.

研究成果: ジャーナルへの寄稿記事

Transcription Factor TFIID
Apoptosis
Mutation
Viral Tumor Antigens
Polyomavirus Transforming Antigens
1994
50 引用 (Scopus)

Hydroxyl radical generation in skeletal muscle atrophied by immobilization

Kondo, H., Nishino, K. & Itokawa, Y., 8 1 1994, : : FEBS Letters. 349, 2, p. 169-72 4 p.

研究成果: ジャーナルへの寄稿記事

Immobilization
Hydroxyl Radical
Muscle
Skeletal Muscle
Salicylates
4 引用 (Scopus)

Mammalian cells have two functional RCC1 proteins produced by alternative splicing

Miyabashira, J., Sekiguchi, T. & Nishimoto, T., 8 1 1994, : : Journal of Cell Science. 107, 8, p. 2203-2208 6 p.

研究成果: ジャーナルへの寄稿記事

Alternative Splicing
Complementary DNA
Cricetinae
Exons
Proteins
10 引用 (Scopus)

Minimum essential region of CCG1/TAFII250 required for complementing the temperature-sensitive cell cycle mutants, tsBN462 and ts13 cells, of hamster BHK21 cells

Noguchi, E., Sekiguchi, T., Nohiro, Y., Hayashida, T., Hirose, E., Hayashi, N. & Nishimoto, T., 11 1 1994, : : Somatic Cell and Molecular Genetics. 20, 6, p. 505-513 9 p.

研究成果: ジャーナルへの寄稿記事

Cricetinae
Cell Cycle
Yeasts
Transcription Factor TFIID
HMGB1 Protein
1 引用 (Scopus)

Preliminary findings of chromosomal alterations and expression of cell cycle genes in head an neck tumors

Nakashima, T., Masuda, A., Sekiguchi, T., Nishimoto, T. & Uemura, T., 8 1 1994, : : European Archives of Oto-Rhino-Laryngology. 251, 1 Supplement, p. S87-S90

研究成果: ジャーナルへの寄稿記事

cdc Genes
Thyroid Gland
Neck
Head
CDC2 Protein Kinase
12 引用 (Scopus)

Structure of the human CCG1 gene: relationship between the exons/introns and functional domain/modules of the protein

Torahiko, N., Takeshi, S., Hidetoshi, S., Kei, Y., Shirou, T., Mitiko, G., Juha, K., David, S. & Takeharu, N., 4 20 1994, : : Gene. 141, 2, p. 193-200 8 p.

研究成果: ジャーナルへの寄稿記事

Introns
Exons
Genes
Cell Cycle Checkpoints
Proteins
56 引用 (Scopus)

The CCG1/TAFII250 gene is mutated in thermosensitive G1 mutants of the BHK21 cell line derived from golden hamster

Toshiro, H., Sekiguchi, T., Eishi, N., Hidetoshi, S., Tomoyuki, O. & Takeharu, N., 4 20 1994, : : Gene. 141, 2, p. 267-270 4 p.

研究成果: ジャーナルへの寄稿記事

Mesocricetus
Complementary DNA
Cell Line
General Transcription Factors
Genes
1993
44 引用 (Scopus)

Antioxidant enzyme systems in skeletal muscle atrophied by immobilization

Kondo, H., Miura, M. & Itokawa, Y., 1 1993, : : Pflugers Archiv European Journal of Physiology. 422, 4, p. 404-6 3 p.

研究成果: ジャーナルへの寄稿記事

Immobilization
Muscle
Skeletal Muscle
Antioxidants
Superoxide Dismutase
136 引用 (Scopus)

Mechanism of oxidative stress in skeletal muscle atrophied by immobilization

Kondo, H., Nakagaki, I., Sasaki, S., Hori, S. & Itokawa, Y., 12 1993, : : American Journal of Physiology - Cell Physiology. 265, 6 Pt 1, p. E839-44

研究成果: ジャーナルへの寄稿記事

Immobilization
Hydrogen Peroxide
Skeletal Muscle
Oxidative Stress
Superoxides
17 引用 (Scopus)

Molecular cloning and identification of two types of hamster cyclin-dependent kinases: CDK2 and CDK2L

Noguchi, E., Sekiguchi, T., Yamashita, K. & Nishimoto, T., 12 30 1993, : : Biochemical and Biophysical Research Communications. 197, 3, p. 1524-1529 6 p.

研究成果: ジャーナルへの寄稿記事

Cyclin-Dependent Kinase 2
Cyclin-Dependent Kinases
Cloning
Molecular Cloning
Cricetinae
198 引用 (Scopus)

Molecular cloning of a human cDNA encoding a novel protein, DAD1, whose defect causes apoptotic cell death in hamster BHK21 cells

Nakashima, T., Sekiguchi, T., Kuraoka, A., Fukushima, K., Shibata, Y., Komiyama, S. & Nishimoto, T., 10 1993, : : Molecular and cellular biology. 13, 10, p. 6367-6374 8 p.

研究成果: ジャーナルへの寄稿記事

Molecular Cloning
Cricetinae
Cell Death
Complementary DNA
Apoptosis