小児科

研究成果 2000 2020

2020

Molecular mechanisms determining severity in patients with Pierson syndrome

Minamikawa, S., Miwa, S., Inagaki, T., Nishiyama, K., Kaito, H., Ninchoji, T., Yamamura, T., Nagano, C., Sakakibara, N., Ishimori, S., Hara, S., Yoshikawa, N., Hirano, D., Harada, R., Hamada, R., Matsunoshita, N., Nagata, M., Shima, Y., Nakanishi, K., Nagase, H. および4人, Takeda, H., Morisada, N., Iijima, K. & Nozu, K., 1 1 2020, (受理済み/印刷中) : : Journal of Human Genetics.

研究成果: ジャーナルへの寄稿記事

Laminin
Phenotype
Glomerular Basement Membrane
Pierson syndrome
Nephrotic Syndrome

Prognostic factors for survival of herpes simplex virus-associated hemophagocytic lymphohistiocytosis

Sonoda, M., Ishimura, M., Eguchi, K., Shiraishi, A., Kanno, S., Kaku, N., Inoue, H., Motomura, Y., Ochiai, M., Sakai, Y., Nakayama, M., Ohara, O. & Ohga, S., 1 1 2020, : : International journal of hematology. 111, 1, p. 131-136 6 p.

研究成果: ジャーナルへの寄稿記事

Hemophagocytic Lymphohistiocytosis
Simplexvirus
Fever
Survival
Interferons

Survival and ocular preservation in a long-term cohort of Japanese patients with retinoblastoma

Ueda, T., Koga, Y., Yoshikawa, H., Tanabe, M., Yamana, K., Oba, U., Nakashima, K., Ono, H., Ichimura, T., Hasegawa, S., Kato, W., Kobayashi, T., Nakayama, H., Sakai, Y., Yoshitake, T., Ohga, S., Oda, Y., Suzuki, S., Sonoda, K. H. & Ohga, S., 1 28 2020, : : BMC Pediatrics. 20, 1, 37.

研究成果: ジャーナルへの寄稿記事

公開
Retinoblastoma
Second Primary Neoplasms
Drug Therapy
Survival
Survivors
2019

A child with prostaglandin I2-associated thyrotoxicosis: Case report

Sonoda, Y., Yamamura, K., Ishii, K., Ohkubo, K., Ihara, K., Sakai, Y. & Ohga, S., 6 2019, : : JCRPE Journal of Clinical Research in Pediatric Endocrinology. 11, 2, p. 207-210 4 p.

研究成果: ジャーナルへの寄稿記事

公開
Thyrotoxicosis
Epoprostenol
Hyperthyroidism
Pulmonary Hypertension
Thyroid Gland

An acute encephalopathy with reduced diffusion in BRAF-associated cardio-facio-cutaneous syndrome

Okuzono, S., Fukai, R., Noda, M., Miyake, N., Lee, S., Kaku, N., Sanefuji, M., Akamine, S., Kanno, S., Ishizaki, Y., Torisu, H., Kira, R., Matsumoto, N., Sakai, Y. & Ohga, S., 4 2019, : : Brain and Development. 41, 4, p. 378-381 4 p.

研究成果: ジャーナルへの寄稿記事

Brain Diseases
Exome
Mutation
Inborn Genetic Diseases
Sick Leave

A nationwide survey on tracheostomy for very-low-birth-weight infants in Japan

on behalf of the Neonatal Research Network of Japan, 1 2019, : : Pediatric Pulmonology. 54, 1, p. 53-60 8 p.

研究成果: ジャーナルへの寄稿記事

Very Low Birth Weight Infant
Tracheostomy
Japan
Odds Ratio
Parturition

Association of perinatal factors of epilepsy in very low birth weight infants, using a nationwide database in Japan

on behalf of the Neonatal Research Network of Japan (NRNJ), 11 1 2019, : : Journal of Perinatology. 39, 11, p. 1472-1479 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Very Low Birth Weight Infant
Epilepsy
Japan
Databases
Odds Ratio

Chemokine levels predict progressive liver disease in Down syndrome patients with transient abnormal myelopoiesis

Kinjo, T., Inoue, H., Kusuda, T., Fujiyoshi, J., Ochiai, M., Takahata, Y., Honjo, S., Koga, Y., Hara, T. & Ohga, S., 8 2019, : : Pediatrics and Neonatology. 60, 4, p. 382-388 7 p.

研究成果: ジャーナルへの寄稿記事

Down Syndrome
Chemokines
Liver Failure
Liver Diseases
Chemokine CXCL9

Clinical Utility of Highly Purified 10% Liquid Intravenous Immunoglobulin in Kawasaki Disease

Oda, T., Nagata, H., Nakashima, Y., Nanishi, E., Takada, Y., Nishimura, M., Kubo, E., Hatae, K. & Ohga, S., 11 2019, : : Journal of Pediatrics. 214, p. 227-230 4 p.

研究成果: ジャーナルへの寄稿記事

Mucocutaneous Lymph Node Syndrome
Intravenous Immunoglobulins
Fever
Therapeutics

Critical association of Pallister–Hall syndrome and congenital heart disease

Ochiai, M., Nagata, H., Tanaka, K., Ihara, K. & Ohga, S., 1 1 2019, : : Pediatrics International. 61, 8, p. 827-828 2 p.

研究成果: ジャーナルへの寄稿記事

Pallister-Hall Syndrome
Heart Diseases
2 引用 (Scopus)

Diagnostic challenge of the newborn patients with heritable protein C deficiency

Ichiyama, M., Inoue, H., Ochiai, M., Ishimura, M., Shiraishi, A., Fujiyoshi, J., Yamashita, H., Sato, K., Matsumoto, S., Hotta, T., Uchiumi, T., Kang, D. & Ohga, S., 2 1 2019, : : Journal of Perinatology. 39, 2, p. 212-219 8 p.

研究成果: ジャーナルへの寄稿記事

Protein C Deficiency
Protein C
Protein S
Newborn Infant
Mutation

Early Intervention With Adrenocorticotropin for Acute Encephalopathy-Associated Epileptic Spasms: Report of Two Cases

Yonemoto, K., Ichimiya, Y., Sanefuji, M., Kaku, N., Sakata, A., Baba, R., Yamashita, F., Akamine, S., Torio, M., Ishizaki, Y., Maehara, Y., Sakai, Y. & Ohga, S., 1 1 2019, : : Clinical EEG and Neuroscience. 50, 1, p. 51-55 5 p.

研究成果: ジャーナルへの寄稿記事

Spasm
Brain Diseases
Adrenocorticotropic Hormone
Electroencephalography
Sick Leave
2 引用 (Scopus)
Tetralogy of Fallot
Liver Cirrhosis
Carcinoma
Liver
Hyaluronic Acid
1 引用 (Scopus)

Epstein-Barr virus-associated γδ T-cell lymphoproliferative disorder associated with hypomorphic IL2RG mutation

Tanita, K., Hoshino, A., Imadome, K. I., Kamiya, T., Inoue, K., Okano, T., Yeh, T. W., Yanagimachi, M., Shiraishi, A., Ishimura, M., Schober, T., Rohlfs, M., Takagi, M., Imai, K., Takada, H., Ohga, S., Klein, C., Morio, T. & Kanegane, H., 1 1 2019, : : Frontiers in Pediatrics. 7, FEB, 15.

研究成果: ジャーナルへの寄稿記事

公開
Lymphoproliferative Disorders
Human Herpesvirus 4
T-Lymphocytes
Mutation
Infectious Mononucleosis
Ventricular Outflow Obstruction
Ductus Arteriosus
Patient Rights
Parturition
Incidence

Inflammation in the neonatal period and intrauterine growth restriction aggravate bronchopulmonary dysplasia

Kurata, H., Ochiai, M., Inoue, H., Kusuda, T., Fujiyoshi, J., Ichiyama, M., Wakata, Y. & Takada, H., 10 2019, : : Pediatrics and Neonatology. 60, 5, p. 496-503 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Bronchopulmonary Dysplasia
Inflammation
Growth
Positive-Pressure Respiration
Gestational Age

Intrahepatic cholangiocarcinoma after the Fontan procedure

Shibui, Y., Kohashi, K., Sakamoto, I., Yamamura, K. & Oda, Y., 3 2019, : : Human Pathology: Case Reports. 15, p. 15-19 5 p.

研究成果: ジャーナルへの寄稿記事

Fontan Procedure
Cholangiocarcinoma
Liver Cirrhosis
Heart Failure
Liver

Late-Onset Circulatory Collapse and Risk of Cerebral Palsy in Extremely Preterm Infants

Yasuoka, K., Inoue, H., Egami, N., Ochiai, M., Tanaka, K., Sawano, T., Kurata, H., Ichiyama, M., Fujiyoshi, J., Matsushita, Y., Sakai, Y. & Ohga, S., 9 1 2019, : : Journal of Pediatrics. 212, p. 117-123.e4

研究成果: ジャーナルへの寄稿記事

Extremely Premature Infants
Cerebral Palsy
Shock
Delayed Diagnosis
Hypotension

Management of apnea in infants with trisomy 18

Taira, R., Inoue, H., Sawano, T., Fujiyoshi, J., Ichimiya, Y., Torio, M., Sanefuji, M., Ochiai, M., Sakai, Y. & Ohga, S., 1 1 2019, (受理済み/印刷中) : : Developmental Medicine and Child Neurology.

研究成果: ジャーナルへの寄稿記事

Apnea
Positive-Pressure Respiration
Epilepsy
Trisomy 18
Neonatal Intensive Care Units
4 引用 (Scopus)

Mode of death and predictors of mortality in adult Fontan survivors: A Japanese multicenter observational study

On behalf of the JSACHD Fontan Investigators, 2 1 2019, : : International Journal of Cardiology. 276, p. 74-80 7 p.

研究成果: ジャーナルへの寄稿記事

Multicenter Studies
Observational Studies
Survivors
Mortality
Survival Rate
Myocarditis
Thrombosis
Pediatrics
Equipment and Supplies
Extracorporeal Membrane Oxygenation

Peripartum management of pregnant women with congenital heart disease

Yamasaki, K., Sawatari, H., Konagai, N., Kamiya, C. A., Yoshimatsu, J., Muneuchi, J., Watanabe, M., Fukuda, T., Mizuno, A., Sakamoto, I., Yamamura, K., Ohkusa, T., Tsutsui, H., Niwa, K. & Chishaki, A., 1 1 2019, : : Circulation Journal. 83, 11, p. 2257-2264 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Peripartum Period
Pregnant Women
Heart Diseases
Maternal Age
Parity

Posttransplant recipient-derived CD4 + T-cell lymphoproliferative disease in X-linked hyper-IgM syndrome

Hagio, Y., Shiraishi, A., Ishimura, M., Sonoda, M., Eguchi, K., Yamamoto, H., Oda, Y. & Ohga, S., 3 2019, : : Pediatric Blood and Cancer. 66, 3, e27529.

研究成果: ジャーナルへの寄稿レター

Type 1 Hyper-IgM Immunodeficiency Syndrome
T-Lymphocytes

Procalcitonin levels predicting the infliximab response of immunoglobulin resistant Kawasaki disease

Nakashima, Y., Nanishi, E., Yamamura, K., Uike, K., Terashi, E., Hirata, Y., Nagata, H., Morihana, E., Tanaka, T., Honjo, S., Takada, H. & Ohga, S., 2 2019, : : Cytokine. 114, p. 26-31 6 p.

研究成果: ジャーナルへの寄稿記事

Mucocutaneous Lymph Node Syndrome
Calcitonin
Immunoglobulins
Intravenous Immunoglobulins
Serum
3 引用 (Scopus)

Right ventricular fibrosis is associated with cardiac remodelling after pulmonary valve replacement

Yamamura, K., Yuen, D., Hickey, E. J., He, X., Chaturvedi, R. R., Friedberg, M. K., Grosse-Wortmann, L., Hanneman, K., Billia, F., Farkouh, M. E. & Wald, R. M., 6 1 2019, : : Heart. 105, 11, p. 855-863 9 p.

研究成果: ジャーナルへの寄稿記事

Pulmonary Valve
Fibrosis
Tetralogy of Fallot
Collagen
Heart Failure
1 引用 (Scopus)

S100A4 Protein Is Essential for the Development of Mature Microfold Cells in Peyer's Patches

Kunimura, K., Sakata, D., Tun, X., Uruno, T., Ushijima, M., Katakai, T., Shiraishi, A., Aihara, R., Kamikaseda, Y., Matsubara, K., Kanegane, H., Sawa, S., Eberl, G., Ohga, S., Yoshikai, Y. & Fukui, Y., 11 26 2019, : : Cell Reports. 29, 9, p. 2823-2834.e7

研究成果: ジャーナルへの寄稿記事

公開
Peyer's Patches
Cytokine Receptors
Domes
Muramidase
Cells

Successful stent implantation for acute take-off left coronary artery stenosis

Mori, S., Nagata, H., Sakamoto, I., Oi, K. & Ohga, S., 9 1 2019, : : Pediatrics International. 61, 9, p. 933-935 3 p.

研究成果: ジャーナルへの寄稿コメント/討論

Coronary Stenosis
Stents
1 引用 (Scopus)

Systemic Epstein-Barr virus-positive T/NK lymphoproliferative diseases with SH2D1a/XIAP hypomorphic gene variants

Ishimura, M., Eguchi, K., Shiraishi, A., Sonoda, M., Azuma, Y., Yamamoto, H., Imadome, K. I. & Ohga, S., 1 1 2019, : : Frontiers in Pediatrics. 7, MAY, 183.

研究成果: ジャーナルへの寄稿記事

公開
Epstein-Barr Virus Infections
Human Herpesvirus 4
Genes
Natural Killer Cells
Lymphoproliferative Disorders
1 引用 (Scopus)
公開
Hepatolenticular Degeneration
Deciduous Tooth
Inbred LEC Rats
Hepatocytes
Stem Cells
2018
3 引用 (Scopus)

A male case with CDKL5-associated encephalopathy manifesting transient methylmalonic acidemia

Akamine, S., Ishizaki, Y., Sakai, Y., Torisu, H., Fukai, R., Miyake, N., Ohkubo, K., Koga, H., Sanefuji, M., Sakata, A., Kimura, M., Yamaguchi, S., Sakamoto, O., Hara, T., Saitsu, H., Matsumoto, N. & Ohga, S., 8 2018, : : European Journal of Medical Genetics. 61, 8, p. 451-454 4 p.

研究成果: ジャーナルへの寄稿記事

Brain Diseases
Mutation
Methylmalonic Acid
Exome
Infantile Spasms

A rightward saccade to an unexpected stimulus as a marker for lateralised visuospatial attention /631/378/2649/1310 /631/378/2617/1795 /631/477/2811 article

Sanefuji, M., Yamashita, H., Torio, M., Katsuki, D., Akamine, S., Ishizaki, Y., Kishimoto, J., Sakai, Y., Takada, H., Yoshida, K. & Ohga, S., 12 1 2018, : : Scientific reports. 8, 1, 7562.

研究成果: ジャーナルへの寄稿記事

Saccades
Reaction Time
Task Performance and Analysis
Healthy Volunteers
Brain
9 引用 (Scopus)

Association of severity of coronary artery aneurysms in patients with kawasaki disease and risk of later coronary events

Z-score Project 2nd Stage Study Group, 5 2018, : : JAMA Pediatrics. 172, 5, e180030.

研究成果: ジャーナルへの寄稿記事

公開
Coronary Aneurysm
Mucocutaneous Lymph Node Syndrome
Coronary Vessels
Intravenous Immunoglobulins
Passive Immunization
1 引用 (Scopus)

Complement activation associated with ADAMTS13 deficiency may contribute to the characteristic glomerular manifestations in Upshaw-Schulman syndrome

Itami, H., Hara, S., Matsumoto, M., Imamura, S., Kanai, R., Nishiyama, K., Ishimura, M., Ohga, S., Yoshida, M., Tanaka, R., Ogawa, Y., Asada, Y., Sekita-Hatakeyama, Y., Hatakeyama, K. & Ohbayashi, C., 10 2018, : : Thrombosis Research. 170, p. 148-155 8 p.

研究成果: ジャーナルへの寄稿記事

Thrombotic Thrombocytopenic Purpura
Complement Activation
Complement Membrane Attack Complex
Complement C5b
Staining and Labeling
5 引用 (Scopus)

Comprehensive screening for monogenic diabetes in 89 Japanese children with insulin-requiring antibody-negative type 1 diabetes

The Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes, 3 2018, : : Pediatric Diabetes. 19, 2, p. 243-250 8 p.

研究成果: ジャーナルへの寄稿記事

Insulin Antibodies
Type 1 Diabetes Mellitus
Mutation
Autoantibodies
Genes

Diagnostic potential of stored dried blood spots for inborn errors of metabolism: A metabolic autopsy of medium-chain acyl-CoA dehydrogenase deficiency

Kaku, N., Ihara, K., Hirata, Y., Yamada, K., Lee, S., Kanemasa, H., Motomura, Y., Baba, H., Tanaka, T., Sakai, Y., Maehara, Y. & Ohga, S., 10 1 2018, : : Journal of Clinical Pathology. 71, 10, p. 885-889 5 p.

研究成果: ジャーナルへの寄稿記事

Inborn Errors Metabolism
Autopsy
Molecular Biology
Cause of Death
Newborn Infant

Dynamic flow imaging using 320-detector row CT and motion coherence analysis in coronary aneurysms associated with Kawasaki disease

Shimomiya, Y., Nagao, M., Yamasaki, Y., Shirasaka, T., Kondo, M., Kojima, T., Nishie, A., Yamamura, K. & Honda, H., 3 1 2018, : : Cardiology in the Young. 28, 3, p. 416-420 5 p.

研究成果: ジャーナルへの寄稿記事

Coronary Aneurysm
Mucocutaneous Lymph Node Syndrome
Coronary Vessels
Aneurysm
Diastole
1 引用 (Scopus)

Early-onset epileptic encephalopathy and severe developmental delay in an association with de novo double mutations in NF1 and MAGEL2

Akamine, S., Sagata, N., Sakai, Y., Kato, T. A., Nakahara, T., Matsushita, Y., Togao, O., Hiwatashi, A., Sanefuji, M., Ishizaki, Y., Torisu, H., Saitsu, H., Matsumoto, N., Hara, T., Sawa, A., Kano, S., Furue, M., Kanba, S., Shaw, C. A. & Ohga, S., 1 1 2018, : : Epilepsia Open. 3, 1, p. 81-85 5 p.

研究成果: ジャーナルへの寄稿記事

公開
Neurofibromatosis 1
Brain Diseases
Mutation
Exome
Genes
2 引用 (Scopus)

Effective infliximab therapy for the early regression of coronary artery aneurysm in Kawasaki disease

Nagatomo, Y., Muneuchi, J., Nakashima, Y., Nanishi, E., Shirozu, H., Watanabe, M., Uike, K., Nagata, H., Hirata, Y., Yamamura, K., Takahashi, Y., Okada, S., Suzuki, Y., Hasegawa, S. & Ohga, S., 11 15 2018, : : International Journal of Cardiology. 271, p. 317-321 5 p.

研究成果: ジャーナルへの寄稿記事

Coronary Aneurysm
Mucocutaneous Lymph Node Syndrome
Coronary Vessels
Therapeutics
Infliximab
1 引用 (Scopus)

Effective shunt closure for pulmonary hypertension and liver dysfunction in congenital portosystemic venous shunt

Uike, K., Nagata, H., Hirata, Y., Yamamura, K., Terashi, E., Matsuura, T., Morihana, E., Ohkubo, K., Ishii, K., Sakai, Y., Taguchi, T. & Ohga, S., 4 2018, : : Pediatric Pulmonology. 53, 4, p. 505-511 7 p.

研究成果: ジャーナルへの寄稿記事

Pulmonary Hypertension
Liver Diseases
Hypertension
Patent Ductus Venosus
Vascular Malformations

Fever and skin involvement at diagnosis predicting the intractable langerhans cell histiocytosis: 40 case-series in a single center

Kobayashi, T., Koga, Y., Ishimura, M., Nakashima, K., Kato, W., Ono, H., Sonoda, M., Eguchi, K., Fukano, R., Honjo, S., Oda, Y. & Ohga, S., 1 1 2018, : : Journal of Pediatric Hematology/Oncology. 40, 3, p. e148-e153

研究成果: ジャーナルへの寄稿記事

Langerhans Cell Histiocytosis
Fever
Skin
Confidence Intervals
Interleukin-2 Receptors
1 引用 (Scopus)
Heart Diseases
Angiography
Electrocardiography
Respiration
Computed Tomography Angiography
1 引用 (Scopus)

High incidence of progressive stenosis in aberrant left subclavian artery with right aortic arch

Muraoka, M., Nagata, H., Hirata, Y., Uike, K., Terashi, E., Morihana, E., Ochiai, M., Fujita, Y., Kato, K., Yamamura, K. & Ohga, S., 3 1 2018, : : Heart and Vessels. 33, 3, p. 309-315 7 p.

研究成果: ジャーナルへの寄稿記事

Thoracic Aorta
Pathologic Constriction
Incidence
Vertebral Artery
Parturition
1 引用 (Scopus)
Pregnancy Outcome
Pulmonary Artery
Coronary Vessels

Lysosomal membrane permeabilization causes secretion of IL-1β in human vascular smooth muscle cells

Ono, H., Ohta, R., Kawasaki, Y., Niwa, A., Takada, H., Nakahata, T., Ohga, S. & Saito, M. K., 10 1 2018, : : Inflammation Research. 67, 10, p. 879-889 11 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-1
Vascular Smooth Muscle
Smooth Muscle Myocytes
Inflammasomes
Membranes

Medical equipment deployment in pediatric emergency prehospital medical units in Japan

Kaku, N., Nitta, M., Muguruma, T., Hirata, Y., Tsukahara, K., Knaup, E., Nosaka, N. & Enomoto, Y., 1 2018, : : Pediatrics International. 60, 1, p. 93-95 3 p.

研究成果: ジャーナルへの寄稿記事

Japan
Emergencies
Pediatrics
Equipment and Supplies
Ambulances

Metabolic and immunological assessment of small-for-gestational-age children during one-year treatment with growth hormone: The clinical impact of apolipoproteins

Kojima-Ishii, K., Toda, N., Okubo, K., Tocan, V., Ohyama, N., Makimura, M., Matsuo, T., Ochiai, M., Ohga, S. & Ihara, K., 1 1 2018, : : Endocrine Journal. 65, 4, p. 449-459 11 p.

研究成果: ジャーナルへの寄稿記事

Apolipoproteins
Growth Hormone
Gestational Age
Therapeutics
Serum
2 引用 (Scopus)

Neurodevelopmental outcomes in infants with birth weight ≤500 g at 3 years of age

Inoue, H., Ochiai, M., Sakai, Y., Yasuoka, K., Tanaka, K., Ichiyama, M., Kurata, H., Fujiyoshi, J., Matsushita, Y., Honjo, S., Nonaka, K., Taguchi, T., Kato, K. & Ohga, S., 12 2018, : : Pediatrics. 142, 6, e20174286.

研究成果: ジャーナルへの寄稿記事

Birth Weight
Confidence Intervals
Odds Ratio
Periventricular Leukomalacia
Necrotizing Enterocolitis
2 引用 (Scopus)

Nontuberculous mycobacteria-associated hemophagocytic lymphohistiocytosis in MonoMAC syndrome

Eguchi, K., Ishimura, M., Sonoda, M., Ono, H., Shiraishi, A., Kanno, S., Koga, Y., Takada, H. & Ohga, S., 7 2018, : : Pediatric Blood and Cancer. 65, 7, e27017.

研究成果: ジャーナルへの寄稿レター

Hemophagocytic Lymphohistiocytosis
Nontuberculous Mycobacteria

Ocular findings in a case of Pierson syndrome with a novel mutation in laminin ß2 gene

Arima, M., Tsukamoto, S., Akiyama, R., Nishiyama, K., Kohno, R. I., Tachibana, T., Hayashida, A., Murayama, M., Hisatomi, T., Nozu, K., Iijima, K., Ohga, S. & Sonoda, K., 10 1 2018, : : Journal of AAPOS. 22, 5, p. 401-403.e1

研究成果: ジャーナルへの寄稿記事

Laminin
Iris
Mutation
Eye Abnormalities
Genes
1 引用 (Scopus)
Heart Diseases
Coronary Vessels
Angiography
Aorta
Electrocardiography