研究成果 1983 2019

フィルター
評論記事
2019

Chronopharmacological strategies focused on chrono-drug discovery

Ohdo, S., Satoru, K. & Naoya, M., 10 1 2019, : : Pharmacology and Therapeutics. 202, p. 72-90 19 p.

研究成果: ジャーナルへの寄稿評論記事

Drug Discovery
Periodicity
Chronic Renal Insufficiency
Pharmaceutical Preparations
Neoplastic Stem Cells
1 引用 (Scopus)

Circulating messenger for neuroprotection induced by molecular hydrogen

Noda, M., Uemura, Y., Yoshii, Y., Horita, T., Takemi, S., Sakata, I. & Sakai, T., 1 1 2019, : : Canadian Journal of Physiology and Pharmacology. 97, 10, p. 909-915 7 p.

研究成果: ジャーナルへの寄稿評論記事

Ghrelin
Hydrogen
Drinking Water
Oxidative Stress
Ghrelin Receptor
4 引用 (Scopus)

Clinical Pharmacokinetics of Anaplastic Lymphoma Kinase Inhibitors in Non-Small-Cell Lung Cancer

Hirota, T., Muraki, S. & Ieiri, I., 4 4 2019, : : Clinical Pharmacokinetics. 58, 4, p. 403-420 18 p.

研究成果: ジャーナルへの寄稿評論記事

Non-Small Cell Lung Carcinoma
Pharmacokinetics
Pharmaceutical Preparations
Cytochrome P-450 Enzyme System
Cytochrome P-450 CYP3A
1 引用 (Scopus)

Metabolic plasticity of astrocytes and aging of the brain

Morita, M., Ikeshima-Kataoka, H., Kreft, M., Vardjan, N., Zorec, R. & Noda, M., 2 2 2019, : : International journal of molecular sciences. 20, 4, 941.

研究成果: ジャーナルへの寄稿評論記事

公開
plastic properties
Astrocytes
brain
Plasticity
Brain

Microglia-neuron interactions in the models of neuropathic pain

Saitoh, H. & Makoto, T., 11 1 2019, : : Biochemical Pharmacology. 169, 113614.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Neurons
Chronic Pain
Chemical activation
1 引用 (Scopus)

Mitochondrial dynamics in exercise physiology

Tanaka, T., Nishimura, A., Nishiyama, K., Goto, T., Numaga-Tomita, T. & Nishida, M., 1 1 2019, : : Pflugers Archiv European Journal of Physiology.

研究成果: ジャーナルへの寄稿評論記事

Mitochondrial Dynamics
Physiology
Organelle Biogenesis
Post Translational Protein Processing
Homeostasis
2 引用 (Scopus)

TRPC channels in exercise-mimetic therapy

Numaga-Tomita, T., Oda, S., Nishiyama, K., Tanaka, T., Nishimura, A. & Nishida, M., 3 7 2019, : : Pflugers Archiv European Journal of Physiology. 471, 3, p. 507-517 11 p.

研究成果: ジャーナルへの寄稿評論記事

Exercise Therapy
Muscle
Mechanical Stress
Proteins
Oxidative stress
2018
6 引用 (Scopus)

Astrocytes in the spinal dorsal horn and chronic itch

Makoto, T., 1 1 2018, : : Neuroscience Research. 126, p. 9-14 6 p.

研究成果: ジャーナルへの寄稿評論記事

Atopic Dermatitis
Astrocytes
Peripheral Nervous System
Central Nervous System
Skin

Epigenetic regulation of pharmacokinetic-related genes in human tissues

Hirota, T., 1 1 2018, : : Yakugaku Zasshi. 138, 11, p. 1391-1396 6 p.

研究成果: ジャーナルへの寄稿評論記事

Epigenomics
Pharmacokinetics
Breast Neoplasms
Pharmaceutical Preparations
Genes

Green Pharma: A new strategy for drug discovery in academia by targeting glial cells and ATP receptors

Yamashita, T., Makoto, T., Saitoh, H. & Inoue, K., 1 1 2018, : : Yakugaku Zasshi. 138, 8, p. 1027-1031 5 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Drug Discovery
Neuroglia
Hyperalgesia
Neuralgia
47 引用 (Scopus)

Microglia in neuropathic pain: Cellular and molecular mechanisms and therapeutic potential

Inoue, K. & Makoto, T., 2 16 2018, : : Nature Reviews Neuroscience. 19, 3, p. 138-152 15 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Chronic Pain
Nociceptive Pain
Peripheral Nerve Injuries
14 引用 (Scopus)

Modulation of Pain and Itch by Spinal Glia

Makoto, T., 2 1 2018, : : Neuroscience Bulletin. 34, 1, p. 178-185 8 p.

研究成果: ジャーナルへの寄稿評論記事

Neuroglia
Chronic Pain
Pain
Spinal Cord
Posterior Horn Cells
3 引用 (Scopus)

Therapeutic targets for treatment of heart failure: Focus on GRKs and β-arrestins affecting βaR signaling

Mangmool, S., Parichatikanond, W. & Kurose, H., 11 27 2018, : : Frontiers in Pharmacology. 9, NOV, 01336.

研究成果: ジャーナルへの寄稿評論記事

Arrestins
G-Protein-Coupled Receptor Kinases
Treatment Failure
Heart Failure
Adrenergic Receptors
2017
4 引用 (Scopus)

Epigenetic regulation of drug transporter expression in human tissues

Hirota, T., Tanaka, T., Takesue, H. & Ieiri, I., 1 2 2017, : : Expert Opinion on Drug Metabolism and Toxicology. 13, 1, p. 19-30 12 p.

研究成果: ジャーナルへの寄稿評論記事

Drug and Narcotic Control
Epigenomics
Tissue
Pharmaceutical Preparations
Genes

Microglia and its phagocytic abilities.

Noda, M., 2017, : : Clinical Pathophysiology. 23, 1, p. 11-18 8 p., 22(1).

研究成果: ジャーナルへの寄稿評論記事

Microglia
Phagocytosis
Ficus
Cytophagocytosis
Nerve Tissue
37 引用 (Scopus)

Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex

Makoto, T., Koga, K., Chen, T. & Zhuo, M., 5 1 2017, : : Journal of Neurochemistry. 141, 4, p. 486-498 13 p.

研究成果: ジャーナルへの寄稿評論記事

Gyrus Cinguli
Neurology
Neuralgia
Chronic Pain
Pain
26 引用 (Scopus)

P2 receptors, microglial cytokines and chemokines, and neuropathic pain

Makoto, T., 6 1 2017, : : Journal of Neuroscience Research. 95, 6, p. 1319-1329 11 p.

研究成果: ジャーナルへの寄稿評論記事

Cytokine Receptors
Chemokine Receptors
Neuralgia
Microglia
Peripheral Nerve Injuries
6 引用 (Scopus)

Purinergic P2Y6 receptors: A new therapeutic target of age-dependent hypertension

Sunggip, C., Nishimura, A., Shimoda, K., Numaga-Tomita, T., Makoto, T. & Nishida, M., 6 1 2017, : : Pharmacological Research. 120, p. 51-59 9 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic Receptors
Hypertension
Angiotensin Type 1 Receptor
clopidogrel
Purinergic P2Y12 Receptors
18 引用 (Scopus)

Purinergic P2Y receptors: Molecular diversity and implications for treatment of cardiovascular diseases

Nishimura, A., Sunggip, C., Oda, S., Numaga-Tomita, T., Makoto, T. & Nishida, M., 12 1 2017, : : Pharmacology and Therapeutics. 180, p. 113-128 16 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2Y Receptors
G-Protein-Coupled Receptors
Cardiovascular System
Cardiovascular Diseases
Uracil Nucleotides
6 引用 (Scopus)

Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells

Nishida, M., Nishimura, A., Matsunaga, T., Motohashi, H., Kasamatsu, S. & Akaike, T., 8 1 2017, : : Free Radical Biology and Medicine. 109, p. 132-140 9 p.

研究成果: ジャーナルへの寄稿評論記事

Metabolism
Oxidation-Reduction
Nitric Oxide
Cardiovascular Physiological Phenomena
Cell signaling

Roles and educational effects of clinical case studies in home medical care

Ohsawa, T. & Shimazoe, T., 1 1 2017, : : Yakugaku Zasshi. 137, 8, p. 947-956 10 p.

研究成果: ジャーナルへの寄稿評論記事

Home Care Services
Pharmacists
Students
Education
Diagnostic Self Evaluation
3 引用 (Scopus)

Spinal dorsal horn astrocytes: New players in chronic itch

Tsuda, M., 1 1 2017, : : Allergology International. 66, 1, p. 31-35 5 p.

研究成果: ジャーナルへの寄稿評論記事

Atopic Dermatitis
Astrocytes
Skin
Spinal Cord Dorsal Horn
Therapeutics
2016
NADPH Oxidase
Nicotinic Receptors
Microglia
Nicotine
Protons
17 引用 (Scopus)

Myofibroblasts and inflammatory cells as players of cardiac fibrosis

Kurose, H. & Mangmool, S., 8 1 2016, : : Archives of Pharmacal Research. 39, 8, p. 1100-1113 14 p.

研究成果: ジャーナルへの寄稿評論記事

Myofibroblasts
Fibrosis
Collagen
Fibroblasts
Cells
40 引用 (Scopus)

Neuron-microglia interaction by purinergic signaling in neuropathic pain following neurodegeneration

Tsuda, M. & Inoue, K., 5 1 2016, : : Neuropharmacology. 104, p. 76-81 6 p.

研究成果: ジャーナルへの寄稿評論記事

Microglia
Neuralgia
Neurons
Purinergic P2Y Receptors
Purinergic P2X Receptors

New mechanism for chronic itch in the nervous system

Makoto, T. & Shiratori, M., 1 1 2016, : : Seikagaku. 88, 5, p. 654-656 3 p.

研究成果: ジャーナルへの寄稿評論記事

Neurology
Animals
Astrocytes
Atopic Dermatitis
14 引用 (Scopus)

Redox signaling regulated by an electrophilic cyclic nucleotide and reactive cysteine persulfides

Fujii, S., Sawa, T., Nishida, M., Ihara, H., Ida, T., Motohashi, H. & Akaike, T., 4 1 2016, : : Archives of Biochemistry and Biophysics. 595, p. 140-146 7 p.

研究成果: ジャーナルへの寄稿評論記事

Cyclic Nucleotides
Metabolism
Oxidation-Reduction
Oxidants
Reactive Oxygen Species
21 引用 (Scopus)

Redox signaling regulated by electrophiles and reactive sulfur species

Nishida, M., Kumagai, Y., Ihara, H., Fujii, S., Motohashi, H. & Akaike, T., 3 2016, : : Journal of Clinical Biochemistry and Nutrition. 58, 2, p. 91-98 8 p.

研究成果: ジャーナルへの寄稿評論記事

Sulfur
Oxidative stress
Oxidation-Reduction
Cell signaling
Metabolism
2015

Bone and Calcium Research Update 2015. Basic mechanisms underlying calcium signaling and their biological potentiality

Mori, Y., Mori, M. X. & Nishida, M., 1 1 2015, : : Clinical calcium. 25, 1, p. 47-58 12 p.

研究成果: ジャーナルへの寄稿評論記事

Calcium Signaling
Ions
Calcium
Biological Phenomena
Bone and Bones
30 引用 (Scopus)

Drug-drug interactions that interfere with statin metabolism

Hirota, T. & Ieiri, I., 9 2 2015, : : Expert Opinion on Drug Metabolism and Toxicology. 11, 9, p. 1435-1447 13 p.

研究成果: ジャーナルへの寄稿評論記事

Drug interactions
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Drug Interactions
Metabolism
Pharmaceutical Preparations
2 引用 (Scopus)
Neuralgia
Purinergic P2X4 Receptors
Neuroglia
Microglia
Peripheral Nerve Injuries
1 引用 (Scopus)
Biological Transport
Hypoglycemic Agents
Pharmacokinetics
Kidney
Liver
13 引用 (Scopus)
Thyroid Hormones
Mental Disorders
Neuroglia
Thyroid Gland
Central Nervous System

Research on molecular mechanisms of engulfment of apoptotic cells

Nakaya, M., 8 1 2015, : : Yakugaku Zasshi. 135, 8, p. 949-954 6 p.

研究成果: ジャーナルへの寄稿評論記事

Phagocytes
Research
Macrophages
Time-Lapse Imaging
Cytophagocytosis

The physiological role of G protein-coupled receptor kinase

Ohba, Y. & Michio, N., 10 1 2015, : : Seikagaku. The Journal of Japanese Biochemical Society. 87, 5, p. 612-616 5 p.

研究成果: ジャーナルへの寄稿評論記事

2014
1 引用 (Scopus)

Molecular basis of choronopharmacology

Satoru, K., 1 1 2014, : : Seikagaku. 86, 6, p. 774-777 4 p.

研究成果: ジャーナルへの寄稿評論記事

Liver
Antineoplastic Agents
Cytochrome P-450 Enzyme System
Carrier Proteins
Animals
39 引用 (Scopus)

Multiple functions of G protein-coupled receptor kinases

Watari, K., Nakaya, M. & Kurose, H., 3 6 2014, : : Journal of Molecular Signaling. 9, 1, 1.

研究成果: ジャーナルへの寄稿評論記事

G-Protein-Coupled Receptor Kinases
Arrestin
GTP-Binding Proteins
Phosphorylation
G-Protein-Coupled Receptor Kinase 2
8 引用 (Scopus)

Role of 8-nitro-cGMP and its redox regulation in cardiovascular electrophilic signaling

Nishida, M., Toyama, T. & Akaike, T., 1 1 2014, : : Journal of Molecular and Cellular Cardiology. 73, p. 10-17 8 p.

研究成果: ジャーナルへの寄稿評論記事

Cardiovascular System
Reactive Oxygen Species
Nitric Oxide
Gasotransmitters
Cardiovascular Diseases
46 引用 (Scopus)

The glial perspective of autism spectrum disorders

Zeidán-Chuliá, F., Salmina, A. B., Malinovskaya, N. A., Noda, M., Verkhratsky, A. & Moreira, J. C. F., 1 1 2014, : : Neuroscience and Biobehavioral Reviews. 38, p. 160-172 13 p.

研究成果: ジャーナルへの寄稿評論記事

Neuroglia
Autistic Disorder
Plastics
Homeostasis
Central Nervous System
Osteoporosis
Pharmacokinetics
Pharmaceutical Preparations
Population
Bone Remodeling
2013
1 引用 (Scopus)

[Chrono-drug delivery system based on the circadian rhythm of transferrin receptor].

Naoya, M., Okazaki, F., Satoru, K. & Ohdo, S., 1 1 2013, : : Unknown Journal. 71, 12, p. 2200-2205 6 p.

研究成果: ジャーナルへの寄稿評論記事

circadian rhythm
Transferrin Receptors
Drug Delivery Systems
Circadian Rhythm
ligand
1 引用 (Scopus)

[Function and role of transient receptor potential channels].

Nishida, M., Sumita, M. & Kitajima, N., 1 1 2013, : : Clinical calcium. 23, 4, p. 561-568 8 p.

研究成果: ジャーナルへの寄稿評論記事

Transient Receptor Potential Channels
Cations
Intracellular Signaling Peptides and Proteins
Heart Failure
Proteins
13 引用 (Scopus)

Clinical impact of genetic variants of drug transporters in different ethnic groups within and across regions

Ono, C., Kikkawa, H., Suzuki, A., Suzuki, M., Yamamoto, Y., Ichikawa, K., Fukae, M. & Ieiri, I., 1 1 2013, : : Pharmacogenomics. 14, 14, p. 1745-1764 20 p.

研究成果: ジャーナルへの寄稿評論記事

Ethnic Groups
Pharmaceutical Preparations
Precision Medicine
Far East
Pharmacokinetics
30 引用 (Scopus)

Exploring the multifactorial nature of autism through computational systems biology: Calcium and the Rho GTPase RAC1 under the spotlight

Zeidán-Chuliá, F., Rybarczyk-Filho, J. L., Salmina, A. B., De Oliveira, B. H. N., Noda, M. & Moreira, J. C. F., 6 1 2013, : : NeuroMolecular Medicine. 15, 2, p. 364-383 20 p.

研究成果: ジャーナルへの寄稿評論記事

rho GTP-Binding Proteins
Systems Biology
Autistic Disorder
Computational Biology
Calcium
35 引用 (Scopus)

Formation, signaling functions, and metabolisms of nitrated cyclic nucleotide

Sawa, T., Ihara, H., Ida, T., Fujii, S., Nishida, M. & Akaike, T., 1 1 2013, : : Nitric Oxide - Biology and Chemistry. 34, p. 10-18 9 p.

研究成果: ジャーナルへの寄稿評論記事

Cyclic Nucleotides
Metabolism
Protein S
Proteins
Cell signaling
64 引用 (Scopus)

Impact of genetic polymorphisms in CYP2C9 and CYP2C19 on the pharmacokinetics of clinically used drugs

Hirota, T., Eguchi, S. & Ieiri, I., 1 1 2013, : : Drug Metabolism and Pharmacokinetics. 28, 1, p. 28-37 10 p.

研究成果: ジャーナルへの寄稿評論記事

Genetic Polymorphisms
Pharmacokinetics
Pharmaceutical Preparations
Precision Medicine
Xenobiotics
77 引用 (Scopus)

Microglial regulation of neuropathic pain

Tsuda, M., Masuda, T., Tozaki-Saitoh, H. & Inoue, K., 2 26 2013, : : Journal of Pharmacological Sciences. 121, 2, p. 89-94 6 p.

研究成果: ジャーナルへの寄稿評論記事

Neuralgia
Microglia
Wounds and Injuries
Posterior Horn Cells
Gene Expression
60 引用 (Scopus)

P2X4 receptors and neuropathic pain

Tsuda, M., Masuda, T., Tozaki-Saitoh, H. & Inoue, K., 10 28 2013, : : Frontiers in Cellular Neuroscience. OCT, 191.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2X4 Receptors
Microglia
Neuralgia
Chemokine CCL21
CCR Receptors
7 引用 (Scopus)

Redox control of cardiovascular homeostasis by angiotensin II

Sunggip, C., Kitajima, N. & Nishida, M., 2013, : : Current Pharmaceutical Design. 19, 17, p. 3022-3032 11 p.

研究成果: ジャーナルへの寄稿評論記事

Angiotensin II
Oxidation-Reduction
Reactive Oxygen Species
Homeostasis
Enzymes
19 引用 (Scopus)

Regulation of redox signalling by an electrophilic cyclic nucleotide

Akaike, T., Nishida, M. & Fujii, S., 2 1 2013, : : Journal of biochemistry. 153, 2, p. 131-138 8 p.

研究成果: ジャーナルへの寄稿評論記事

Cyclic Nucleotides
Oxidation-Reduction
Reactive Oxygen Species
Signal transduction
Signal Transduction