研究成果 1976 2019

2019

Alginate immobilization of Morus alba L. cell suspension cultures improved the accumulation and secretion of stilbenoids

Inyai, C., Boonsnongcheep, P., Komaikul, J., Sritularak, B., Tanaka, H. & Putalun, W., 1 30 2019, : : Bioprocess and Biosystems Engineering. 42, 1, p. 131-141 11 p.

研究成果: ジャーナルへの寄稿記事

Morus
Alginate
Resveratrol
Immobilized Cells
Immobilization

A method to induce hen egg lysozyme-specific humoral immune tolerance in mice by pre-exposition with the protein's oligomers

Ohkuri, T., Yuge, N., Sato, K. & Ueda, T., 12 1 2019, : : Biochemistry and Biophysics Reports. 20, 100679.

研究成果: ジャーナルへの寄稿記事

公開
Immune Tolerance
Oligomers
Antibodies
Anti-Idiotypic Antibodies
Proteins
1 引用 (Scopus)

An indirect competitive enzyme-linked immunosorbent assay toward the standardization of Pueraria candollei based on its unique isoflavonoid, kwakhurin

Yusakul, G., Togita, R., Minami, K., Chanpokapaiboon, K., Juengwatanatrakul, T., Putalun, W., Tanaka, H., Sakamoto, S. & Morimoto, S., 3 1 2019, : : Fitoterapia. 133, p. 23-28 6 p.

研究成果: ジャーナルへの寄稿記事

Pueraria
Enzyme-Linked Immunosorbent Assay
Estrogen Replacement Therapy
Bovine Serum Albumin
Limit of Detection

Anti-allergic activity of polyphenolic compounds isolated from olive mill wastes

Mwakalukwa, R., Ashour, A., Amen, Y., Niwa, Y., Tamrakar, S., Miyamoto, T. & Shimizu, K., 7 1 2019, : : Journal of Functional Foods. 58, p. 207-217 11 p.

研究成果: ジャーナルへの寄稿記事

Anti-Allergic Agents
Olea
Inhibitory Concentration 50
polyphenols
Calcium Channels
1 引用 (Scopus)

Crystal structure and calcium-induced conformational changes of diacylglycerol kinase α EF-hand domains

Takahashi, D., Suzuki, K., Sakamoto, T., Iwamoto, T., Murata, T. & Sakane, F., 4 1 2019, : : Protein Science. 28, 4, p. 694-706 13 p.

研究成果: ジャーナルへの寄稿記事

Diacylglycerol Kinase
EF Hand Motifs
Crystal structure
Calcium
Phosphatidic Acids

Development of a simple and rapid method for the detection of isomiroestrol in Pueraria candollei by an immunochromatographic strip test

Chaingam, J., Kitisripanya, T., Krittanai, S., Sakamoto, S., Tanaka, H. & Putalun, W., 6 14 2019, : : Journal of Natural Medicines. 73, 3, p. 577-583 7 p.

研究成果: ジャーナルへの寄稿記事

Pueraria
Standardization
Benzopyrans
Gold Colloid
Immunosorbents
1 引用 (Scopus)

Diacylglycerol kinase α-selective inhibitors induce apoptosis and reduce viability of melanoma and several other cancer cell lines

Yamaki, A., Akiyama, R., Murakami, C., Takao, S., Murakami, Y., Mizuno, S., Takahashi, D., Kado, S., Taketomi, A., Shirai, Y., Goto, K. & Sakane, F., 6 1 2019, : : Journal of Cellular Biochemistry. 120, 6, p. 10043-10056 14 p.

研究成果: ジャーナルへの寄稿記事

Diacylglycerol Kinase
Melanoma
Phosphotransferases
Phosphatidic Acids
Cells

Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory

Li, R. S., Fukumori, R., Takeda, T., Song, Y., Morimoto, S., Kikura-Hanajiri, R., Yamaguchi, T., Watanabe, K., Aritake, K., Tanaka, Y., Yamada, H., Yamamoto, T. & Ishii, Y., 7 3 2019, : : Scientific reports. 9, 1, 1 p.

研究成果: ジャーナルへの寄稿記事

公開
Endocannabinoids
Cannabinoids
Learning
Brain-Derived Neurotrophic Factor
Brain
公開
Escherichia coli Proteins
Cell Division
Proteins
AT Rich Sequence
DNA Polymerase III

Evaluation of the immunomodulatory effects of fucoidan derived from cladosiphon okamuranus tokida in mice

Tomori, M., Nagamine, T., Miyamoto, T. & Iha, M., 9 24 2019, : : Marine Drugs. 17, 10, 547.

研究成果: ジャーナルへの寄稿記事

公開
Humoral Immunity
Cellular Immunity
Macrophages
Cell Proliferation
Phaeophyta

Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure

Igawa, T., Kishikawa, S., Abe, Y., Yamashita, T., Nagai, S., Shiroishi, M., Shinozaki, C., Tanaka, H., Tozaki-Saitoh, H., Tsuda, M., Inoue, K. & Ueda, T., 1 25 2019, : : Purinergic Signalling.

研究成果: ジャーナルへの寄稿記事

Purinergic P2X4 Receptors
Monoclonal Antibodies
Antibodies
Purinergic P2X Receptors
Head
1 引用 (Scopus)

Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure

Igawa, T., Kishikawa, S., Abe, Y., Yamashita, T., Nagai, S., Shiroishi, M., Shinozaki, C., Tanaka, H., Saitoh, H., Makoto, T., Inoue, K. & Ueda, T., 1 1 2019, (受理済み/印刷中) : : Purinergic Signalling.

研究成果: ジャーナルへの寄稿記事

Purinergic P2X4 Receptors
Monoclonal Antibodies
Antibodies
Purinergic P2X Receptors
Head

Expression, Purification, and Characterization of Human Diacylglycerol Kinase ζ

Saito, T., Takahashi, D. & Sakane, F., 3 19 2019, : : ACS Omega. 4, 3, p. 5540-5546 7 p.

研究成果: ジャーナルへの寄稿記事

公開
Diacylglycerol Kinase
Purification
Enzymes
Dichroism
Agglomeration

Hederagenin glycosides from the fruits of Blighia unijugata

Petit, B., Mitaine-Offer, A. C., Delaude, C., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., 6 1 2019, : : Phytochemistry. 162, p. 260-269 10 p.

研究成果: ジャーナルへの寄稿記事

Blighia
Glycosides
Fruits
glycosides
Fruit
1 引用 (Scopus)

Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation of TRPC3 channel and NADPH oxidase 2 protein complexes

Nishiyama, K., Numaga-Tomita, T., Fujimoto, Y., Tanaka, T., Toyama, C., Nishimura, A., Yamashita, T., Naoya, M., Satoru, K., Azuma, Y. T., Ibuki, Y., Uchida, K., Ohdo, S. & Nishida, M., 9 1 2019, : : British Journal of Pharmacology. 176, 18, p. 3723-3738 16 p.

研究成果: ジャーナルへの寄稿記事

NADPH Oxidase
Doxorubicin
Tobacco Smoke Pollution
Proteins
Pharmaceutical Preparations

Improvement of stilbenoid production by 2-hydroxypropyl-β-cyclodextrin in white mulberry (Morus alba L.) callus cultures

Komaikul, J., Kitisripanya, T., Likhitwitayawuid, K., Sritularak, B., Tanaka, H. & Putalun, W., 10 2 2019, : : Natural Product Research. 33, 19, p. 2762-2769 8 p.

研究成果: ジャーナルへの寄稿記事

stilbenoids
Morus
Morus alba
cyclodextrins
Bony Callus

Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib

Morii, I., Iwabuchi, Y., Mori, S., Suekuni, M., Natsume, T., Yoshida, K., Sugimoto, N., Kanemaki, M. T. & Fujita, M., 3 1 2019, : : Cancer Science. 110, 3, p. 1044-1053 10 p.

研究成果: ジャーナルへの寄稿記事

公開
Cisplatin
Platinum Compounds
Neoplasms
Papillomaviridae
DNA Helicases
1 引用 (Scopus)
Bacterial DNA
Single-Stranded DNA
DNA Replication
Dimers
Escherichia coli

Investigation of the endoplasmic reticulum localization of UDP-glucuronosyltransferase 2B7 with systematic deletion mutants

Miyauchi, Y., Kimura, S., Kimura, A., Kurohara, K., Hirota, Y., Fujimoto, K., Mackenzie, P. I., Tanaka, Y. & Ishii, Y., 5 1 2019, : : Molecular Pharmacology. 95, 5, p. 551-562 12 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Endoplasmic Reticulum
lysyllysine
Calnexin
Microscopy
1 引用 (Scopus)

Isolation and identification of new anthraquinones from Rhamnus alaternus L and evaluation of their free radical scavenging activity

Ben Ammar, R., Miyamoto, T., Chekir-Ghedira, L., Ghedira, K. & Lacaille-Dubois, M. A., 1 17 2019, : : Natural Product Research. 33, 2, p. 280-286 7 p.

研究成果: ジャーナルへの寄稿記事

Rhamnus
Anthraquinones
anthraquinones
Scavenging
Free Radicals

Magnetic particles-based enzyme immunoassay for rapid determination of secoiridoid glycoside, amarogentin

Sakamoto, S., Wada, S., Morita, Y., Yamaguchi, T., Tanaka, H. & Morimoto, S., 3 1 2019, : : Talanta. 194, p. 731-736 6 p.

研究成果: ジャーナルへの寄稿記事

Iridoid Glycosides
Enzymes
Food additives
amarogentin
Immunosorbents
1 引用 (Scopus)

Marine natural products from Indonesian waters

Hanif, N., Murni, A., Tanaka, C. & Tanaka, J., 6 19 2019, : : Marine Drugs. 17, 6, 364.

研究成果: ジャーナルへの寄稿評論記事

公開
Biological Products
Biodiversity
Water
Organic Chemistry
Aquatic Organisms

Melanogenesis Inhibitors from the Endophytic Fungus Aspergillus amstelodami

Elsbaey, M., Sallam, A., El-Metwally, M., Nagata, M., Tanaka, C., Shimizu, K. & Miyamoto, T., 1 1 2019, : : Chemistry and Biodiversity. 16, 8, e1900237.

研究成果: ジャーナルへの寄稿記事

Arbutin
Melanin
Anti-Allergic Agents
Electrospray ionization
Aspergillus

Microarray analysis of gene expression in the diacylglycerol kinase η knockout mouse brain

Komenoi, S., Suzuki, Y., Asami, M., Murakami, C., Hoshino, F., Chiba, S., Takahashi, D., Kado, S. & Sakane, F., 9 1 2019, : : Biochemistry and Biophysics Reports. 19, 100660.

研究成果: ジャーナルへの寄稿記事

公開
Diacylglycerol Kinase
Microarray Analysis
Microarrays
Bipolar Disorder
Gene expression
Colforsin
Immunoglobulin G
Antigens
Enzyme-Linked Immunosorbent Assay
Bombyx

Myristic acid specifically stabilizes diacylglycerol kinase δ protein in C2C12 skeletal muscle cells

Iwata, K., Sakai, H., Takahashi, D. & Sakane, F., 7 1 2019, : : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 7, p. 1031-1038 8 p.

研究成果: ジャーナルへの寄稿記事

Diacylglycerol Kinase
Myristic Acid
Muscle Cells
Skeletal Muscle
Proteins
oxaliplatin
Hyperalgesia
Pharmacology
Small Molecule Libraries
Peripheral Nervous System Diseases

New secondary metabolites from the mangrove endophytic fungus Aspergillus versicolor

Elsbaey, M., Tanaka, C. & Miyamoto, T., 8 1 2019, : : Phytochemistry Letters. 32, p. 70-76 7 p.

研究成果: ジャーナルへの寄稿記事

Aspergillus versicolor
Hydroxy Acids
Aspergillus
Metabolites
Fungi

Nuciferols A and B: Novel sesquineolignans from Cocos nucifera

Elsbaey, M., Jie, B., Tanaka, C., Kato, H., Tsukamoto, S., Usui, K., Hirai, G. & Miyamoto, T., 8 15 2019, : : Tetrahedron Letters. 60, 33, 150948.

研究成果: ジャーナルへの寄稿記事

Cocos
Scavenging
Neuroprotective Agents
Cell death
Skeleton

Pentacylic triterpenes from Lavandula coronopifolia: structure related inhibitory activity on α-glucosidase

Elsbaey, M., Mwakalukwa, R., Shimizu, K. & Miyamoto, T., 1 1 2019, (受理済み/印刷中) : : Natural Product Research.

研究成果: ジャーナルへの寄稿記事

Lavandula
Glucosidases
Triterpenes
glucosidases
triterpenoids

Phytostilbenoid production in white mulberry (Morus alba L.) cell culture using bioreactors and simple deglycosylation by endogenous enzymatic hydrolysis

Komaikul, J., Kitisripanya, T., Inyai, C., Likhitwitayawuid, K., Sritularak, B., Tanaka, H. & Putalun, W., 4 15 2019, : : In Vitro Cellular and Developmental Biology - Plant. 55, 2, p. 199-208 10 p.

研究成果: ジャーナルへの寄稿記事

Morus
Morus alba
Bioreactors
enzymatic hydrolysis
bioreactors

Preincubation format for a sensitive immunochromatographic assay for monocrotaline, a toxic pyrrolizidine alkaloid

Yusakul, G., Sakamoto, S., Chanpokapaiboon, K., Tanaka, H. & Morimoto, S., 11 1 2019, : : Phytochemical Analysis. 30, 6, p. 653-660 8 p.

研究成果: ジャーナルへの寄稿記事

monocrotaline
Immunochromatography
Monocrotaline
Pyrrolizidine Alkaloids
immunoaffinity chromatography

Preparation of a highly specific single chain variable fragment antibody targeting miroestrol and its application in quality control of Pueraria candollei by enzyme-linked immunosorbent assay

Pongkitwitoon, B., Boonsnongcheep, P., Kitisripanya, T., Yusakul, G., Sakamoto, S., Tanaka, H., Morimoto, S. & Putalun, W., 11 1 2019, : : Phytochemical Analysis. 30, 6, p. 600-608 9 p.

研究成果: ジャーナルへの寄稿記事

Pueraria
Single-Chain Antibodies
Immunosorbents
Quality Control
quality control
Thermococcus
Replication Protein A
DNA-Directed DNA Polymerase
Single-Stranded DNA
DNA
7 引用 (Scopus)

Selective and reversible modification of kinase cysteines with chlorofluoroacetamides

Shindo, N., Fuchida, H., Sato, M., Watari, K., Shibata, T., Kuwata, K., Miura, C., Okamoto, K., Hatsuyama, Y., Tokunaga, K., Sakamoto, S., Morimoto, S., Abe, Y., Shiroishi, M., Caaveiro, J. M. M., Ueda, T., Tamura, T., Matsunaga, N., Nakao, T., Koyanagi, S. および5人, Ohdo, S., Yamaguchi, Y., Hamachi, I., Ono, M. & Ojida, A., 1 14 2019, : : Nature Chemical Biology.

研究成果: ジャーナルへの寄稿記事

Quinazolines
Epidermal Growth Factor Receptor
Cysteine
Phosphotransferases
Hydrolysis

Specific basic patch-dependent multimerization of Saccharomyces cerevisiae ORC on single-stranded DNA promotes ATP hydrolysis

Kawakami, H., Muraoka, R., Ohashi, E., Kawabata, K., Kanamoto, S., Chichibu, T., Tsurimoto, T. & Katayama, T., 9 1 2019, : : Genes to Cells. 24, 9, p. 608-618 11 p.

研究成果: ジャーナルへの寄稿記事

Origin Recognition Complex
Single-Stranded DNA
Saccharomyces cerevisiae
Hydrolysis
Adenosine Triphosphate
1 引用 (Scopus)

Steroidal glycosides from Ornithogalum dubium Houtt

Andriamisaina, N., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Paululat, T., Lirussi, F. & Lacaille-Dubois, M. A., 4 1 2019, : : Phytochemistry. 160, p. 78-84 7 p.

研究成果: ジャーナルへの寄稿記事

Ornithogalum
Cytotoxicity
glycosides
Cells
cytotoxicity
1 引用 (Scopus)

Synthesis of 12- O-Mono- and Diglycosyl-oxystearates, a New Class of Agonists for the C-type Lectin Receptor Mincle

Van Huy, L., Tanaka, C., Imai, T., Yamasaki, S. & Miyamoto, T., 10 1 2019, : : ACS Medicinal Chemistry Letters. 10, 1, p. 44-49 6 p.

研究成果: ジャーナルへの寄稿記事

C-Type Lectins
Macrophages
NFATC Transcription Factors
Structure-Activity Relationship
Green Fluorescent Proteins

The Isolation of New Pore-Forming Toxins from the Sea Anemone Actinia fragacea Provides Insights into the Mechanisms of Actinoporin Evolution

Morante, K., Bellomio, A., Viguera, A. R., González-Mañas, J. M., Tsumoto, K. & Martinez Caaveiro, J. M., 7 10 2019, : : Toxins. 11, 7

研究成果: ジャーナルへの寄稿記事

公開
Actinium
Sea Anemones
Proteins
Species Specificity
Protein Stability

Triterpenoid saponins from the root bark of haplocoelum congolanum

Pertuit, D., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Tran, D. K., Delaude, C. & Lacaille-Dubois, M. A., 5 1 2019, : : Natural product communications. 14, 5

研究成果: ジャーナルへの寄稿記事

公開
triterpenoid saponins
Saponins
bark
Acids
acids

Δ 9 -Tetrahydrocannabinol elicited 22-kHz ultrasonic vocalization changes after air puff stimulus through CB 1 receptor in adult rats

Myose, T., Shirakawa, A., Irie, K., Yamashita, Y., Nakano, T., Takase, Y., Matsuo, K., Satho, T., Tuchihashi, R., Kinjo, J., Tanaka, H., Morimoto, S., Funada, M., Sano, K. & Mishima, K., 5 14 2019, : : Neuroscience Letters. 701, p. 132-135 4 p.

研究成果: ジャーナルへの寄稿記事

Dronabinol
Ultrasonics
Air
rimonabant
Cannabinoid Receptors
2018
1 引用 (Scopus)

Alleviation of fatty liver in a rat model by enhancing N 1 -methylnicotinamide bioavailability through aldehyde oxidase inhibition

Takeuchi, K., Yokouchi, C., Goto, H., Umehara, K., Yamada, H. & Ishii, Y., 12 9 2018, : : Biochemical and Biophysical Research Communications. 507, 1-4, p. 203-210 8 p.

研究成果: ジャーナルへの寄稿記事

公開
Aldehyde Oxidase
Fatty Liver
Liver
Biological Availability
Rats
2 引用 (Scopus)

A Monoclonal Antibody-Based Enzyme-Linked Immunosorbent Assay for Determination of Homoharringtonine

Pongkitwitoon, B., Sakamoto, S., Nagamitsu, R., Putalun, W., Tanaka, H. & Morimoto, S., 2 28 2018, : : Planta medica. 84, 14, p. 1038-1044 7 p.

研究成果: ジャーナルへの寄稿記事

Immunosorbents
Assays
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
Enzymes
3 引用 (Scopus)

A novel engineered interchain disulfide bond in the constant region enhances the thermostability of adalimumab Fab

Nakamura, H., Oda-Ueda, N., Ueda, T. & Ohkuri, T., 1 1 2018, : : Biochemical and Biophysical Research Communications. 495, 1, p. 7-11 5 p.

研究成果: ジャーナルへの寄稿記事

Disulfides
Pichia
Adalimumab
Computer Simulation
Yeast
7 引用 (Scopus)

Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column

Kiyoshi, M., Caaveiro, J. M. M., Tada, M., Tamura, H., Tanaka, T., Terao, Y., Morante, K., Harazono, A., Hashii, N., Shibata, H., Kuroda, D., Nagatoishi, S., Oe, S., Ide, T., Tsumoto, K. & Ishii-Watabe, A., 12 1 2018, : : Scientific Reports. 8, 1, 3955.

研究成果: ジャーナルへの寄稿記事

Polysaccharides
Antibodies
Column chromatography
Cytotoxicity
Immunoglobulin G
1 引用 (Scopus)

Biophysical analysis of the protein-small molecule interactions to develop small molecule drug discovery

Nagatoishi, S., Martinez Caaveiro, J. M. & Tsumoto, K., 1 1 2018, : : Yakugaku Zasshi. 138, 8, p. 1033-1041 9 p.

研究成果: ジャーナルへの寄稿評論記事

Drug Discovery
Small Molecule Libraries
Thermodynamics
Proteins
Research Personnel
1 引用 (Scopus)

Correction to: Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites (Journal of Natural Medicines, (2018), 72, 1, (32-42), 10.1007/s11418-017-1144-z)

Sakamoto, S., Putalun, W., Vimolmangkang, S., Phoolcharoen, W., Shoyama, Y., Tanaka, H. & Morimoto, S., 1 1 2018, : : Journal of Natural Medicines. 72, 1, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Immunosorbents
Metabolites
Internet
Medicine
Assays

Crystallization of Human Erythrocyte Band 3, the anion exchanger, at the International Space Station “KIBO”

Hatae, H., Inaka, K., Okamura, R., Furubayashi, N., Kamo, M., Kobayashi, T., Abe, Y., Iwata, S. & Hamasaki, N., 10 15 2018, : : Analytical Biochemistry. 559, p. 91-93 3 p.

研究成果: ジャーナルへの寄稿記事

Chloride-Bicarbonate Antiporters
Space stations
Crystallization
Blood
Erythrocytes

Development of a colloidal gold nanoparticle-based immunochromatographic strip for the one-step detection of miroestrol and puerarin

Krittanai, S., Kitisripanya, T., Udomsin, O., Tanaka, H., Sakamoto, S., Juengwatanatrakul, T. & Putalun, W., 11 1 2018, : : Biomedical Chromatography. 32, 11, e4330.

研究成果: ジャーナルへの寄稿記事

Gold Colloid
Nanoparticles
Pueraria
Rejuvenation
Immunosorbents

Development of a Competitive Time-Resolved Fluoroimmunoassay for Paclitaxel

Cui, Q., Tanaka, H., Shoyama, Y., Ye, H. T., Li, F., Tian, E. W., Wu, Y. S. & Chao, Z., 5 1 2018, : : Phytochemical Analysis. 29, 3, p. 284-289 6 p.

研究成果: ジャーナルへの寄稿記事

Fluoroimmunoassay
paclitaxel
Taxus
taxes
Paclitaxel