研究成果 1976 2019

記事

Alpha-mangostin ameliorates bleomycin-induced pulmonary fibrosis in mice partly through activating adenosine 5′-monophosphate-activated protein kinase

Li, R. S., Xu, G. H., Cao, J., Liu, B., Xie, H. F., Ishii, Y. & Zhang, C. F., 1 1 2019, : : Frontiers in Pharmacology. 10, 1305.

研究成果: ジャーナルへの寄稿記事

公開
Pulmonary Fibrosis
Bleomycin
Adenosine Monophosphate
Protein Kinases
Lung
15 引用 (Scopus)

Alteration of the function of the UDP-glucuronosyltransferase 1A subfamily by cytochrome P450 3A4: Different susceptibility for UGT isoforms and UGT1A1/7 variantss

Ishii, Y., Koba, H., Kinoshita, K., Oizaki, T., Iwamoto, Y., Takeda, S., Miyauchi, Y., Nishimura, Y., Egoshi, N., Taura, F., Morimoto, S., Ikushiro, SI., Nagata, K., Yamazoe, Y., MacKenzie, P. I. & Yamada, H., 2 1 2014, : : Drug Metabolism and Disposition. 42, 2, p. 229-238 10 p.

研究成果: ジャーナルへの寄稿記事

Cytochrome P-450 CYP3A
Glucuronosyltransferase
Protein Isoforms
irinotecan
Acids

A metal binding in the polypeptide chain improves the folding efficiency of a denatured and reduced protein

Ohkuri, T., Ueda, T., Yoshida, Y., Abe, Y., Hamasaki, N. & Imoto, T., 7 5 2002, : : Biopolymers. 64, 2, p. 106-114 9 p.

研究成果: ジャーナルへの寄稿記事

Polypeptides
Muramidase
Enzymes
Metals
Proteins
26 引用 (Scopus)
endoproteinase Asp-N
Asparagine
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Muramidase
Viperidae

A method to induce hen egg lysozyme-specific humoral immune tolerance in mice by pre-exposition with the protein's oligomers

Ohkuri, T., Yuge, N., Sato, K. & Ueda, T., 12 1 2019, : : Biochemistry and Biophysics Reports. 20, 100679.

研究成果: ジャーナルへの寄稿記事

公開
Immune Tolerance
Oligomers
Antibodies
Anti-Idiotypic Antibodies
Proteins
2 引用 (Scopus)

A Monoclonal Antibody-Based Enzyme-Linked Immunosorbent Assay for Determination of Homoharringtonine

Pongkitwitoon, B., Sakamoto, S., Nagamitsu, R., Putalun, W., Tanaka, H. & Morimoto, S., 2 28 2018, : : Planta medica. 84, 14, p. 1038-1044 7 p.

研究成果: ジャーナルへの寄稿記事

Immunosorbents
Assays
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
Enzymes
1 引用 (Scopus)

A monoclonal antibody-based immunoassay for the determination of oxyresveratrol from Artocarpus lacucha Buch.-Ham

Kitisripanya, T., Inyai, C., Krittanai, S., Likhitwitayawuid, K., Sritularak, B., Ploypradith, P., Tanaka, H., Morimoto, S. & Putalun, W., 7 1 2017, : : Journal of Natural Medicines. 71, 3, p. 523-530 8 p.

研究成果: ジャーナルへの寄稿記事

Artocarpus
Immunoassay
Monoclonal Antibodies
Assays
Immunosorbents
6 引用 (Scopus)

Amounts of proteins altered by mutations in the dnaA gene of Escherichia coli

Ohba, A., Mizushima, T., Katayama, T. & Sekimizu, K., 3 10 1997, : : FEBS Letters. 404, 2-3, p. 125-128 4 p.

研究成果: ジャーナルへの寄稿記事

Escherichia coli
Genes
Mutation
holo-(acyl-carrier-protein) synthase
Fatty Acid Transport Proteins
12 引用 (Scopus)

Amphimelibiosides A-F, six new ceramide dihexosides isolated from a Japanese marine sponge Amphimedon sp.

Emura, C., Higuchi, R., Miyamoto, T. & Van Soest, R. W. M., 4 15 2005, : : Journal of Organic Chemistry. 70, 8, p. 3031-3038 8 p.

研究成果: ジャーナルへの寄稿記事

Nuclear magnetic resonance
Degradation
ceramide dihexoside
1-octadecene
45 引用 (Scopus)

A mutation study of catalytic residue Asp 52 in hen egg lysozyme

Hashimoto, Y., Yamada, K., Motoshima, H., Omura, T., Yamada, H., Yasukochi, T., Miki, T., Ueda, T. & Imoto, T., 1 1 1996, : : Journal of Biochemistry. 119, 1, p. 145-150 6 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Yeast
Mutation
Extremities
Yeasts
16 引用 (Scopus)

Amyloid formation in denatured single-mutant lysozymes where residual structures are modulated

Mishima, T., Ohkuri, T., Monji, A., Imoto, T. & Ueda, T., 10 9 2006, : : Protein Science. 15, 10, p. 2448-2452 5 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Amyloid
Ports and harbors
Spectrum Analysis
Fluorescence
30 引用 (Scopus)

Amyloid-β fibril formation is not necessarily required for microglial activation by the peptides

Hashioka, S., Monji, A., Ueda, T., Kanba, S. & Nakanishi, H., 10 1 2005, : : Neurochemistry International. 47, 5, p. 369-376 8 p.

研究成果: ジャーナルへの寄稿記事

Amyloid
Peptides
Microglia
Aptitude
Tumor Necrosis Factor-alpha
30 引用 (Scopus)

Amyloid-β-protein (Aβ) (25-35)-associated free radical generation is strongly influenced by the aggregational state of the peptides

Monji, A., Utsumi, H., Ueda, T., Imoto, T., Yoshida, I., Hashioka, S., Tashiro, K. I. & Tashiro, N., 1 4 2002, : : Life Sciences. 70, 7, p. 833-841 9 p.

研究成果: ジャーナルへの寄稿記事

Serum Amyloid A Protein
Free Radicals
Phosphates
Peptides
Buffers
2 引用 (Scopus)
disulfide bonds
Muramidase
lysozyme
Disulfides
Cysteine
4 引用 (Scopus)

Analysis of internal motions of interleukin-13 variant associated with severe bronchial asthma using 15N NMR relaxation measurements

Yoshida, Y., Ohkuri, T., Takeda, C., Kuroki, R., Izuhara, K., Imoto, T. & Ueda, T., 6 22 2007, : : Biochemical and Biophysical Research Communications. 358, 1, p. 292-297 6 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-13
Asthma
Nuclear magnetic resonance
Signal transduction
Mutation

Analysis of internal motions of RNase T1 complexed with a productive substrate involving 15N NMR relaxation measurements

Yoshida, Y., Tanaka, M., Ohkuri, T., Tanaka, Y., Imoto, T. & Ueda, T., 7 1 2006, : : Journal of biochemistry. 140, 1, p. 43-48 6 p.

研究成果: ジャーナルへの寄稿記事

Ribonuclease T1
Nuclear magnetic resonance
Substrates
Guanosine
Linewidth
13 引用 (Scopus)

Analysis of post-lysosomal compartments

Hirota, Y., Masuyama, N., Kuronita, T., Fujita, H., Himeno, M. & Tanaka, Y., 2 6 2004, : : Biochemical and Biophysical Research Communications. 314, 2, p. 306-312 7 p.

研究成果: ジャーナルへの寄稿記事

Lysosomes
Dextrans
Cathepsin D
Hydrolases
Macromolecules
13 引用 (Scopus)

Analysis of the Early Stage of the Folding Process of Reduced Lysozyme Using All Lysozyme Variants Containing a Pair of Cysteines

Shioi, S., Imoto, T. & Ueda, T., 5 11 2004, : : Biochemistry. 43, 18, p. 5488-5493 6 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Cysteine
Disulfides
Guanidine
Glutathione Disulfide
Magnetic Resonance Spectroscopy
Escherichia coli
Replication Origin
DNA
Oligonucleotides
17 引用 (Scopus)

Analysis of the internal motion of free and ligand-bound human lysozyme by use of 15N NMR relaxation measurement: A comparison with those of hen lysozyme

Mine, S., Ueda, T., Hashimoto, Y. & Imoto, T., 1 1 2000, : : Protein Science. 9, 9, p. 1669-1684 16 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Nuclear magnetic resonance
Ligands
Amino Acid Sequence
Amino Acids
47 引用 (Scopus)

Analysis of the relationship between enzyme activity and its internal motion using nuclear magnetic resonance: 15N relaxation studies of wild-type and mutant lysozyme

Mine, S., Tate, S. I., Ueda, T., Kainosho, M. & Imoto, T., 3 12 1999, : : Journal of Molecular Biology. 286, 5, p. 1547-1565 19 p.

研究成果: ジャーナルへの寄稿記事

Glucosamine
Muramidase
Magnetic Resonance Spectroscopy
Enzymes
Catalytic Domain
7 引用 (Scopus)

Analysis of the stability of mutant lysozymes at position 15 using X-ray crystallography

Ohmura, T., Ueda, T., Motoshima, H., Tamura, T. & Imoto, T., 1 1 1997, : : Journal of Biochemistry. 122, 3, p. 512-517 6 p.

研究成果: ジャーナルへの寄稿記事

X ray crystallography
X Ray Crystallography
Muramidase
Hydrogen
Hydrogen bonds
16 引用 (Scopus)

Analysis of the stabilization of hen lysozyme by helix macrodipole and charged side chain interaction

Motoshima, H., Mine, S., Masumoto, K., Abe, Y., Iwashita, H., Hashimoto, Y., Chijiiwa, Y., Ueda, T. & Imoto, T., 1 1 1997, : : Journal of Biochemistry. 121, 6, p. 1076-1081 6 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Stabilization
Hydrogen bonds
Protein Stability
Hydrogen Bonding
24 引用 (Scopus)
Glycyrrhizic Acid
Glycyrrhiza
Lipopolysaccharides
Nitric Oxide
Nitric Oxide Synthase
5 引用 (Scopus)

Analysis of the transition state in the unfolding of hen lysozyme by introduction of Gly-Pro and Pro-Gly sequences at the same site

Motoshima, H., Ueda, T. & Imoto, T., 1 1 1996, : : Journal of biochemistry. 119, 6, p. 1019-1023 5 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Free energy
Catalytic Domain
Conformations
poly(prolylprolylglycine)15
9 引用 (Scopus)

An enzyme-linked immunosorbant assay using monoclonal antibody against bacoside a3 for determination of jujubogenin glycosides in Bacopa Monnieri (L.) wettst

Tothiam, C., Phrompittayarat, W., Putalun, W., Tanaka, H., Sakamoto, S., Khan, I. A. & Ingkaninan, K., 9 1 2011, : : Phytochemical Analysis. 22, 5, p. 385-391 7 p.

研究成果: ジャーナルへの寄稿記事

Bacopa
Bacopa monnieri
Glycosides
glycosides
Assays
21 引用 (Scopus)

An enzyme-linked immunosorbant assay using polyclonal antibodies against bacopaside I

Phrompittayarat, W., Putalun, W., Tanaka, H., Wittaya-Areekul, S., Jetiyanon, K. & Ingkaninan, K., 2 12 2007, : : Analytica Chimica Acta. 584, 1, p. 1-6 6 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
antibody
Assays
assay
enzyme
27 引用 (Scopus)

An enzyme-linked immunosorbent assay for aconitine-type alkaloids using an anti-aconitine monoclonal antibody

Kido, K., Edakuni, K., Morinaga, O., Tanaka, H. & Shoyama, Y., 5 26 2008, : : Analytica Chimica Acta. 616, 1, p. 109-114 6 p.

研究成果: ジャーナルへの寄稿記事

Aconitine
Immunosorbents
alkaloid
Alkaloids
antibody
1 引用 (Scopus)

An Enzyme-linked Immunosorbent Assay for Genistein 7-O-[α-rhamnopyranosyl-(1→6)]-β-glucopyranoside Determination in Derris scandens using a Polyclonal Antibody

Jutathis, K., Kitisripanya, T., Udomsin, O., Inyai, C., Sritularak, B., Tanaka, H. & Putalun, W., 11 1 2016, : : Phytochemical Analysis. 27, 6, p. 336-342 7 p.

研究成果: ジャーナルへの寄稿記事

Derris
Immunosorbents
Genistein
genistein
polyclonal antibodies

An evaluation of some model systems commonly used in the study of the sea anemone toxin equinatoxin II with membranes

Caaveiro, J. M. M., Gutiérrez-Aguirre, I., Tribout, M., Paredes, S. & González-Mañas, J. M., 2000, : : ACTA BIOLOGICA SLOVENICA. 43, 1-2, p. 93-97 5 p.

研究成果: ジャーナルへの寄稿記事

A new approach of indirect enzyme-linked immunosorbent assay for determination of D-glutamic acid through in situ conjugation

Sakamoto, S., Nagamitsu, R., Matsuura, Y., Tsuneura, Y., Kurose, H., Tanaka, H. & Morimoto, S., 5 3 2016, : : Journal of Immunoassay and Immunochemistry. 37, 3, p. 296-306 11 p.

研究成果: ジャーナルへの寄稿記事

Immunosorbents
Glutamic Acid
Anti-Idiotypic Antibodies
Assays
Haptens
5 引用 (Scopus)

A new aromatic compound from the stem bark of Terminalia catappa

Pertuit, D., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Delemasure, S., Dutartre, P. & Lacaille-Dubois, M. A., 1 1 2015, : : Natural Product Communications. 10, 6, p. 1005-1007 3 p.

研究成果: ジャーナルへの寄稿記事

Terminalia catappa
Terminalia
triterpene acids
Triterpenes
sitosterols
11 引用 (Scopus)

A new cannabinoid, Δ6-tetrahydrocannabinol 2'-O-β-D-glucopyranoside, biotransformed by plant tissue

Tanaka, H., Takahashi, R., Morimoto, S. & Shoyama, Y., 1 1 1997, : : Journal of Natural Products. 60, 2, p. 168-170 3 p.

研究成果: ジャーナルへの寄稿記事

Dronabinol
Cannabinoids
Pinellia
Tissue
Experiments
4 引用 (Scopus)

A new ecdysteroid and other constituents from two Dioscorea species

Sautour, M., Canon, F., Miyamoto, T., Dongmo, A. & Lacaille-Dubois, M. A., 7 2008, : : Biochemical Systematics and Ecology. 36, 7, p. 559-563 5 p.

研究成果: ジャーナルへの寄稿記事

Dioscorea
Ecdysteroids
Candida
ecdysteroids
rhizome
3 引用 (Scopus)

A new highly selective and specific anti-puerarin polyclonal antibody for determination of puerarin using a mannich reaction hapten conjugate

Udomsin, O., Krittanai, S., Kitisripanya, T., Tanaka, H. & Putalun, W., 10 1 2017, : : Pharmacognosy Magazine. 13, 52, p. S845-S851

研究成果: ジャーナルへの寄稿記事

Haptens
Enzyme-Linked Immunosorbent Assay
Pueraria
Antibodies
Bovine Serum Albumin
14 引用 (Scopus)

A new oleanane glycoside from the roots of Astragalus caprinus

Mitaine-Offer, A. C., Miyamoto, T., Semmar, N., Jay, M. & Lacaille-Dubois, M. A., 7 1 2006, : : Magnetic Resonance in Chemistry. 44, 7, p. 713-716 4 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
glucosides
Mass spectrometry
mass spectroscopy
Nuclear magnetic resonance
22 引用 (Scopus)

A new phenanthrene glycoside and other constituents from Dioscorea opposita

Sautour, M., Mitaine-Offer, A. C., Miyamoto, T., Wagner, H. & Lacaille-Dubois, M. A., 10 1 2004, : : Chemical and Pharmaceutical Bulletin. 52, 10, p. 1235-1237 3 p.

研究成果: ジャーナルへの寄稿記事

Dioscorea
Rhizome
Palmitic Acid
Candida
Phytochemicals
39 引用 (Scopus)

A new steroidal saponin from Dioscorea cayenensis

Sautour, M., Mitaine-Offer, A. C., Miyamoto, T., Dongmo, A. & Lacaille-Dubois, M. A., 11 1 2004, : : Chemical and Pharmaceutical Bulletin. 52, 11, p. 1353-1355 3 p.

研究成果: ジャーナルへの寄稿記事

Dioscoreaceae
Dioscorea
Rhizome
Candida
Saponins
1 引用 (Scopus)

An immunochromatographic assay for rapid etection of salvinorin A

Paudel, M. K., Shirota, O., Sakamoto, S., Morimoto, S. & Tanaka, H., 7 4 2017, : : Journal of Immunoassay and Immunochemistry. 38, 4, p. 438-448 11 p.

研究成果: ジャーナルへの寄稿記事

salvinorin A
Immunochromatography
Assays
Salvia
Lamiaceae
2 引用 (Scopus)
Muramidase
Methionine
Carbon
Methylation
Myoglobin
2 引用 (Scopus)

An improved method for the purification and characterization of a 54 kDa protein in rat liver which has recently been identified as a selenium-binding protein

Ishida, T., Fukuda, A., Yoshioka, Y., Maji, D., Ishii, Y. & Oguri, K., 1 1 1999, : : Journal of Health Science. 45, 4, p. 203-208 6 p.

研究成果: ジャーナルへの寄稿記事

Selenium-Binding Proteins
Liver
Purification
Rats
Selenium
1 引用 (Scopus)

An indirect competitive enzyme-linked immunosorbent assay toward the standardization of Pueraria candollei based on its unique isoflavonoid, kwakhurin

Yusakul, G., Togita, R., Minami, K., Chanpokapaiboon, K., Juengwatanatrakul, T., Putalun, W., Tanaka, H., Sakamoto, S. & Morimoto, S., 3 1 2019, : : Fitoterapia. 133, p. 23-28 6 p.

研究成果: ジャーナルへの寄稿記事

Pueraria
Enzyme-Linked Immunosorbent Assay
Estrogen Replacement Therapy
Bovine Serum Albumin
Limit of Detection
36 引用 (Scopus)
Muramidase
Histidine
Lysine
Derivatives
Stabilization
43 引用 (Scopus)

An in vitro multistep carcinogenesis model for human cervical cancer

Narisawa-Saito, M., Yoshimatsu, Y., Ohno, S. I., Yugawa, T., Egawa, N., Fujita, M., Hirohashi, S. & Kiyono, T., 7 15 2008, : : Cancer Research. 68, 14, p. 5699-5705 7 p.

研究成果: ジャーナルへの寄稿記事

Uterine Cervical Neoplasms
Carcinogenesis
Oncogenes
Neoplasms
Neoplastic Stem Cells
22 引用 (Scopus)

An isolated Hda-clamp complex is functional in the regulatory inactivation of DnaA and DNA replication

Kawakami, H., Su'etsugu, M. & Katayama, T., 10 1 2006, : : Journal of structural biology. 156, 1, p. 220-229 10 p.

研究成果: ジャーナルへの寄稿記事

DNA Replication
Holoenzymes
DNA Polymerase III
Hydrolysis
Adenosine Triphosphate
13 引用 (Scopus)

An on-membrane quantitative analysis system for glycyrrhizin in licorice roots and traditional Chinese medicines

Morinaga, O., Fujino, A., Tanaka, H. & Shoyama, Y., 10 1 2005, : : Analytical and Bioanalytical Chemistry. 383, 4, p. 668-672 5 p.

研究成果: ジャーナルへの寄稿記事

Glycyrrhizic Acid
Glycyrrhiza
Chinese Traditional Medicine
Medicine
Membranes
28 引用 (Scopus)

A novel analytical ELISA-based methodology for pharmacologically active saikosaponins

Zhu, S., Shimokawa, S., Shoyama, Y. & Tanaka, H., 2 1 2006, : : Fitoterapia. 77, 2, p. 100-108 9 p.

研究成果: ジャーナルへの寄稿記事

Enzyme-Linked Immunosorbent Assay
Aminopterin
Monoclonal Antibodies
Kampo Medicine
Hypoxanthine
4 引用 (Scopus)

A novel anti-microtubule agent with carbazole and benzohydrazide structures suppresses tumor cell growth in vivo

Ohira, M., Iwasaki, Y., Tanaka, C., Kuroki, M., Matsuo, N., Kitamura, T., Yukuhiro, M., Morimoto, H., Pang, N., Liu, B., Kiyono, T., Amemiya, M., Tanaka, K., Yoshida, K., Sugimoto, N., Ohshima, T. & Fujita, M., 5 19 2015, : : Biochimica et Biophysica Acta - General Subjects. 1850, 9, p. 1676-1684 9 p.

研究成果: ジャーナルへの寄稿記事

Cell growth
Microtubules
Tumors
Cells
Growth
12 引用 (Scopus)

A novel class of plant type III polyketide synthase involved in orsellinic acid biosynthesis from Rhododendron dauricum

Taura, F., Iijima, M., Yamanaka, E., Takahashi, H., Kenmoku, H., Saeki, H., Morimoto, S., Asakawa, Y., Kurosaki, F. & Morita, H., 9 27 2016, : : Frontiers in Plant Science. 7, September2016, 1452.

研究成果: ジャーナルへの寄稿記事

polyketide synthases
Rhododendron
biosynthesis
acids
Cannabis sativa
5 引用 (Scopus)

A novel engineered interchain disulfide bond in the constant region enhances the thermostability of adalimumab Fab

Nakamura, H., Oda-Ueda, N., Ueda, T. & Ohkuri, T., 1 1 2018, : : Biochemical and Biophysical Research Communications. 495, 1, p. 7-11 5 p.

研究成果: ジャーナルへの寄稿記事

Disulfides
Pichia
Adalimumab
Computer Simulation
Yeast