研究成果 1976 2020

記事
5 引用 (Scopus)

Site-Specific Turn-On Fluorescent Labeling of DNA-Interacting Protein Using Oligodeoxynucleotides That Modify Lysines to Produce 5,6-Dimethoxy 3-Methyleneisoindolin-1-one

Gatanaga, C., Yang, B., Inadomi, Y., Usui, K., Ota, C., Katayama, T., Suemune, H. & Aso, M., 8 19 2016, : : ACS Chemical Biology. 11, 8, p. 2216-2221 6 p.

研究成果: ジャーナルへの寄稿記事

Oligodeoxyribonucleotides
Labeling
Lysine
DNA
Proteins
17 引用 (Scopus)

Situation of monomethoxypolyethylene glycol covalently attached to lysozyme

So, T., Ueda, T., Abe, Y., Nakamata, T. & Imoto, T., 6 1996, : : Journal of biochemistry. 119, 6, p. 1086-1093 8 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
Immunoglobulin Fab Fragments
monomethoxypolyethylene glycol
5 引用 (Scopus)

Six New Polyacetylenic Alcohols from the Marine Sponges Petrosia sp. and Halichondria sp.

Gabriel, A. F., Li, Z., Kusuda, R., Tanaka, C. & Miyamoto, T., 6 1 2015, : : Chemical and Pharmaceutical Bulletin. 63, 6, p. 469-475 7 p.

研究成果: ジャーナルへの寄稿記事

Petrosia
Porifera
Alcohols
Stereochemistry
K562 Cells
16 引用 (Scopus)

Small guanosine triphosphatase Rho/Rho-associated kinase as a novel regulator of intracellular redistribution of lysosomes in invasive tumor cells

Nishimura, Y., Itoh, K., Yoshioka, K., Uehata, M. & Himeno, M., 1 1 2000, : : Cell and tissue research. 301, 3, p. 341-351 11 p.

研究成果: ジャーナルへの寄稿記事

rho-Associated Kinases
Cathepsin D
Guanosine
Lysosomes
Microtubules
9 引用 (Scopus)

Sodium periodate-mediated conjugation of harringtonine enabling the production of a highly specific monoclonal antibody, and the development of a sensitive quantitative analysis method

Sakamoto, S., Yusakul, G., Tsuneura, Y., Putalun, W., Usui, K., Miyamoto, T., Tanaka, H. & Morimoto, S., 4 7 2017, : : Analyst. 142, 7, p. 1140-1148 9 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal antibodies
quantitative analysis
antibody
Monoclonal Antibodies
Sodium
Leukemia
Derivatives
Cephalotaxus
Immunosorbents
Acute Promyelocytic Leukemia
3 引用 (Scopus)
Leukemia
Derivatives
Cephalotaxus
Immunosorbents
Acute Promyelocytic Leukemia
8 引用 (Scopus)

Solakhasoside, a novel steroidal saponin from Solanum khasianum

Putalun, W., Xuan, L. J., Tanaka, H. & Shoyama, Y., 2 16 1999, : : Journal of Natural Products. 62, 1, p. 181-183 3 p.

研究成果: ジャーナルへの寄稿記事

Solanum
Spectroscopic analysis
Saponins
Fruits
Galactose
16 引用 (Scopus)

Solanum incanum and S. heteracanthum as sources of biologically active steroid glycosides: Confirmation of their synonymy

Manase, M. J., Mitaine-Offer, A. C., Pertuit, D., Miyamoto, T., Tanaka, C., Delemasure, S., Dutartre, P., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., 9 1 2012, : : Fitoterapia. 83, 6, p. 1115-1119 5 p.

研究成果: ジャーナルへの寄稿記事

Solanum
Saponins
Glycosides
Steroids
Spirostans
16 引用 (Scopus)

Solasodine glycoside production by hairy root cultures of Physalis minima Linn.

Putalun, W., Prasarnsiwamai, P., Tanaka, H. & Shoyama, Y., 4 1 2004, : : Biotechnology letters. 26, 7, p. 545-548 4 p.

研究成果: ジャーナルへの寄稿記事

Physalis
Glycosides
Agrobacterium
Sugar (sucrose)
Sucrose
9 引用 (Scopus)

Solubilization of membrane proteins with novel N-acylamino acid detergents

Abe, R., Caaveiro, J. M. M., Kudou, M. & Tsumoto, K., 3 26 2010, : : Molecular BioSystems. 6, 4, p. 677-679 3 p.

研究成果: ジャーナルへの寄稿記事

Surface-Active Agents
Detergents
Membrane Proteins
Acids
Membranes
11 引用 (Scopus)

Solution structure and activity of mouse lysozyme M

Obita, T., Ueda, T. & Imoto, T., 1 1 2003, : : Cellular and Molecular Life Sciences. 60, 1, p. 176-184 9 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Biomolecular Nuclear Magnetic Resonance
Rubiaceae
Glycoside Hydrolases
Substrates
4 引用 (Scopus)

Solution structure of the N-terminal domain of a replication restart primosome factor, PriC, in Escherichia coli

Aramaki, T., Abe, Y., Katayama, T. & Ueda, T., 9 1 2013, : : Protein Science. 22, 9, p. 1279-1286 8 p.

研究成果: ジャーナルへの寄稿記事

Escherichia coli
Biomolecular Nuclear Magnetic Resonance
Oligomerization
DNA
Chemical shift
8 引用 (Scopus)

Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding

Igawa, T., Abe, Y., Tsuda, M., Inoue, K. & Ueda, T., 3 12 2015, : : FEBS Letters. 589, 6, p. 680-686 7 p.

研究成果: ジャーナルへの寄稿記事

Purinergic P2X4 Receptors
Rats
Metals
Head
Cations
13 引用 (Scopus)

Sorting nexin 2-mediated membrane trafficking of c-Met contributes to sensitivity of molecular-targeted drugs

Ogi, S., Fujita, H., Kashihara, M., Yamamoto, C., Sonoda, K., Okamoto, I., Nakagawa, K., Ohdo, S., Tanaka, Y., Kuwano, M. & Ono, M., 5 1 2013, : : Cancer Science. 104, 5, p. 573-583 11 p.

研究成果: ジャーナルへの寄稿記事

Sorting Nexins
Epidermal Growth Factor Receptor
Membranes
Pharmaceutical Preparations
Lung Neoplasms
1 引用 (Scopus)

Species differences in metabolism of a new antiepileptic drug candidate, DSP-0565 [2-(2′-fluoro[1,1′-biphenyl]-2-yl)acetamide]

Yahata, M., Ishii, Y., Nakagawa, T., Watanabe, T. & Bando, K., 5 1 2019, : : Biopharmaceutics and Drug Disposition. 40, 5-6, p. 165-175 11 p.

研究成果: ジャーナルへの寄稿記事

Anticonvulsants
Metabolic Networks and Pathways
Hydrolysis
Dogs
Hepatocytes

Species variation in the enantioselective metabolism of tegafur to 5-fluorouracil among rats, dogs and monkeys

Yamamiya, I., Yoshisue, K., Ishii, Y., Yamada, H. & Yoshida, K. I., 12 1 2014, : : The Journal of pharmacy and pharmacology. 66, 12, p. 1686-1697 12 p.

研究成果: ジャーナルへの寄稿記事

Tegafur
Fluorouracil
Haplorhini
Dogs
Thymidine Phosphorylase

Specific basic patch-dependent multimerization of Saccharomyces cerevisiae ORC on single-stranded DNA promotes ATP hydrolysis

Kawakami, H., Muraoka, R., Ohashi, E., Kawabata, K., Kanamoto, S., Chichibu, T., Tsurimoto, T. & Katayama, T., 9 1 2019, : : Genes to Cells. 24, 9, p. 608-618 11 p.

研究成果: ジャーナルへの寄稿記事

Origin Recognition Complex
Single-Stranded DNA
Saccharomyces cerevisiae
Hydrolysis
Adenosine Triphosphate
9 引用 (Scopus)

Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues

Kawakami, H., Ohashi, E., Kanamoto, S., Tsurimoto, T. & Katayama, T., 10 12 2015, : : Scientific reports. 5, 14929.

研究成果: ジャーナルへの寄稿記事

Origin Recognition Complex
Replication Origin
DNA Replication
DNA
Eukaryota
81 引用 (Scopus)

Specific genomic sequences of E. coli promote replicational initiation by directly reactivating ADP-DnaA

Fujimitsu, K., Senriuchi, T. & Katayama, T., 5 15 2009, : : Genes and Development. 23, 10, p. 1221-1233 13 p.

研究成果: ジャーナルへの寄稿記事

Adenosine Diphosphate
Adenosine Triphosphate
Escherichia coli
Intergenic DNA
Protein Subunits
10 引用 (Scopus)

Sphingolipids and other constituents from Cordia platythyrsa

Tapondjou, L. A., Mitaine-Offer, A. C., Sautour, M., Miyamoto, T. & Lacaille-Dubois, M. A., 12 1 2005, : : Biochemical Systematics and Ecology. 33, 12, p. 1293-1297 5 p.

研究成果: ジャーナルへの寄稿記事

Cordia
Boraginaceae
cerebrosides
Cerebrosides
chemical ecology
17 引用 (Scopus)

Spirostane and cholestane glycosides from the bulbs of Allium nigrum L

Jabrane, A., Ben Jannet, H., Miyamoto, T., Mirjolet, J. F., Duchamp, O., Harzallah-Skhiri, F. & Lacaille-Dubois, M. A., 3 15 2011, : : Food Chemistry. 125, 2, p. 447-455 9 p.

研究成果: ジャーナルへの寄稿記事

Spirostans
Cholestanes
Allium
Glycosides
Galactose
1 引用 (Scopus)

Spirostane-Type Saponins from Dracaena fragrans Yellow Coast

Rezgui, A., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., 1 1 2015, : : Natural product communications. 10, 1, p. 37-38 2 p.

研究成果: ジャーナルへの寄稿記事

Dracaena
Dracaena fragrans
Saponins
Glycosides
saponins
30 引用 (Scopus)

Squid nerve sphingomyelin containing an unusual sphingoid base

Ohashi, Y., Tanaka, T., Akashi, S., Morimoto, S., Kishimoto, Y. & Nagai, Y., 7 1 2000, : : Journal of Lipid Research. 41, 7, p. 1118-1124 7 p.

研究成果: ジャーナルへの寄稿記事

Decapodiformes
Sphingomyelins
Starfish
Ions
Mass spectrometry
12 引用 (Scopus)

Stability studies of saponins in Bacopa monnieri dried ethanolic extracts

Phrompittayarat, W., Wittaya-areekul, S., Jetiyanon, K., Putalun, W., Tanaka, H. & Ingkaninan, K., 11 1 2008, : : Planta medica. 74, 14, p. 1756-1763 8 p.

研究成果: ジャーナルへの寄稿記事

Bacopa
Saponins
Complex Mixtures
Moisture
Lead compounds
45 引用 (Scopus)

Stabilization of hen egg white lysozyme by a cavity-filling mutation

Ohmura, T., Ueda, T., Ootsuka, K., Saito, M. & Imoto, T., 3 31 2001, : : Protein Science. 10, 2, p. 313-320 8 p.

研究成果: ジャーナルへの寄稿記事

Egg White
Muramidase
Stabilization
Mutation
Proteins
19 引用 (Scopus)

Stabilization of lysozyme by introducing N-glycosylation signal sequence

Ueda, T., Iwashita, H., Hashimoto, Y. & Imoto, T., 1 1 1996, : : Journal of Biochemistry. 119, 1, p. 157-161 5 p.

研究成果: ジャーナルへの寄稿記事

Glycosylation
Muramidase
Protein Sorting Signals
Stabilization
Oligosaccharides
35 引用 (Scopus)

Stabilization of lysozyme by the introduction of gly-pro sequence

Ueda, T., Tamura, T., Maeda, Y., Hashimoto, Y., Miki, T., Yamada, H. & Imoto, T., 2 1 1993, : : Protein Engineering, Design and Selection. 6, 2, p. 183-187 5 p.

研究成果: ジャーナルへの寄稿記事

glycylproline
Muramidase
Enzymes
Stabilization
Proline
5 引用 (Scopus)

Stable nucleotide binding to DnaA requires a specific glutamic acid residue within the AAA+ box II motif

Ozaki, S., Noguchi, Y., Nishimura, M. & Katayama, T., 8 1 2012, : : Journal of structural biology. 179, 2, p. 242-250 9 p.

研究成果: ジャーナルへの寄稿記事

Adenosine Diphosphate
Glutamic Acid
Nucleotides
Adenosine Triphosphate
DNA Replication
16 引用 (Scopus)

Stable supply of large amounts of human Fab from the inclusion bodies in E. coli

Fujii, T., Ohkuri, T., Onodera, R. & Ueda, T., 5 1 2007, : : Journal of Biochemistry. 141, 5, p. 699-707 9 p.

研究成果: ジャーナルへの寄稿記事

Inclusion Bodies
Escherichia coli
Urea
Cystamine
Cysteamine
2 引用 (Scopus)

Steady-state and time-resolved fluorescence spectroscopic studies on interaction of the N-terminal region with the hairpin loop of the phytocystain Scb

Doi-Kawano, K., Nishimoto, E., Kouzuma, Y., Takahashi, D., Yamashita, S. & Kimura, M., 7 1 2009, : : Journal of Fluorescence. 19, 4, p. 631-639 9 p.

研究成果: ジャーナルへの寄稿記事

Conformations
Fluorescence
Peptides
Fluorescence Polarization
Papain
1 引用 (Scopus)

Steroidal glycosides from Ornithogalum dubium Houtt

Andriamisaina, N., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Paululat, T., Lirussi, F. & Lacaille-Dubois, M. A., 4 1 2019, : : Phytochemistry. 160, p. 78-84 7 p.

研究成果: ジャーナルへの寄稿記事

Ornithogalum
Cytotoxicity
glycosides
Cells
cytotoxicity
21 引用 (Scopus)

Steroidal saponins and flavan-3-ol glycosides from Dioscorea villosa

Sautour, M., Miyamoto, T. & Lacaille-Dubois, M. A., 1 1 2006, : : Biochemical Systematics and Ecology. 34, 1, p. 60-63 4 p.

研究成果: ジャーナルへの寄稿記事

Saponins
Glycosides
flavan-3-ol
29 引用 (Scopus)

Steroidal saponins from Asparagus acutifolius

Sautour, M., Miyamoto, T. & Lacaille-Dubois, M. A., 10 1 2007, : : Phytochemistry. 68, 20, p. 2554-2562 9 p.

研究成果: ジャーナルへの寄稿記事

Asparagus acutifolius
Spirostans
steroid saponins
Spectroscopic analysis
Saponins
17 引用 (Scopus)

Steroidal saponins from Chlorophytum orchidastrum

Acharya, D., Mitaine-Offer, A. C., Kaushik, N., Miyamoto, T., Paululat, T., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., 1 22 2010, : : Journal of Natural Products. 73, 1, p. 7-11 5 p.

研究成果: ジャーナルへの寄稿記事

Saponins
Cytotoxicity
Sugars
Colonic Neoplasms
Ethanol
7 引用 (Scopus)

Steroidal saponins from dioscorea preussii

Tabopda, T. K., Mitaine-Offer, A. C., Tanaka, C., Miyamoto, T., Mirjolet, J. F., Duchamp, O., Ngadjui, B. T. & Lacaille-Dubois, M. A., 9 2014, : : Fitoterapia. 97, p. 198-203 6 p.

研究成果: ジャーナルへの寄稿記事

Dioscorea
Rhizome
Saponins
Skeleton
Mass Spectrometry
3 引用 (Scopus)

Steroidal saponins from Dracaena marginata

Rezgui, A., Mitaine-Offer, A. C., Pertuit, D., Miyamoto, T., Tanaka, C., Delemasure, S., Dutartre, P. & Lacaille-Dubois, M. A., 4 9 2013, : : Natural Product Communications. 8, 2, p. 157-160 4 p.

研究成果: ジャーナルへの寄稿記事

Dracaena marginata
Dracaena
steroid saponins
Saponins
Mass Spectrometry
38 引用 (Scopus)

Steroidal saponins from Smilax medica and their antifungal activity

Sautour, M., Miyamoto, T. & Lacaille-Dubois, M. A., 10 1 2005, : : Journal of Natural Products. 68, 10, p. 1489-1493 5 p.

研究成果: ジャーナルへの寄稿記事

Smilax
Spectroscopic analysis
Candida
Saponins
Candida albicans
1 引用 (Scopus)

Steroidal saponins from the fruits of Cestrum ruizteranianum

Galarraga, E. M., Mitaine-Offer, A. C., Amaro-Luis, J. M., Miyamoto, T., Tanaka, C., Pouységu, L., Quideau, S., Rojas, L. B. & Lacaille-Duboisa, M. A., 2011, : : Natural Product Communications. 6, 12, p. 1825-1826 2 p.

研究成果: ジャーナルへの寄稿記事

Cestrum
steroid saponins
fruit extracts
Saponins
Glycosides
6 引用 (Scopus)

Steroidal saponins from the fruits of Solanum torvum

Pérez Colmenares, A., Rojas, L. B., Mitaine-Offer, A. C., Pouységu, L., Quideau, S., Miyamoto, T., Tanaka, C., Paululat, T., Usubillaga, A. & Lacaille-Dubois, M. A., 2 1 2013, : : Phytochemistry. 86, p. 137-143 7 p.

研究成果: ジャーナルへの寄稿記事

Spirostans
Solanum torvum
steroid saponins
Solanum
Saponins
21 引用 (Scopus)

Steroidal saponins from the roots of Smilax aspera subsp. mauritanica

Belhouchet, Z., Sautour, M., Miyamoto, T. & Lacaille-Dubois, M. A., 9 1 2008, : : Chemical and Pharmaceutical Bulletin. 56, 9, p. 1324-1327 4 p.

研究成果: ジャーナルへの寄稿記事

Smilax
Liliaceae
Candida
Saponins
Microbial Sensitivity Tests
28 引用 (Scopus)

Steroidal saponins from two species of dracaena

Kougan, G. B., Miyamoto, T., Tanaka, C., Paululat, T., Mirjolet, J. F., Duchamp, O., Sondengam, B. L. & Lacaille-Dubois, M. A., 7 23 2010, : : Journal of Natural Products. 73, 7, p. 1266-1270 5 p.

研究成果: ジャーナルへの寄稿記事

Dracaena
Saponins
Diosgenin
Sapogenins
Colonic Neoplasms
17 引用 (Scopus)

Sterylglucoside catabolism in cryptococcus neoformans with endoglycoceramidase-related protein 2 (EGCrP2), the first steryl-β-glucosidase identified in fungi

Watanabe, T., Ito, T., Goda, H. M., Ishibashi, Y., Miyamoto, T., Ikeda, K., Taguchi, R., Okino, N. & Ito, M., 9 9 2015, : : Journal of Biological Chemistry. 290, 2, p. 1005-1019 15 p.

研究成果: ジャーナルへの寄稿記事

endoglycoceramidase
Glucosidases
Cryptococcus neoformans
Fungi
Glucosides

Structural and In Vitro Functional Analyses of Novel Plant-Produced Anti-Human PD1 Antibody

Rattanapisit, K., Phakham, T., Buranapraditkun, S., Siriwattananon, K., Boonkrai, C., Pisitkun, T., Hirankarn, N., Strasser, R., Abe, Y. & Phoolcharoen, W., 12 1 2019, : : Scientific reports. 9, 1, 15205.

研究成果: ジャーナルへの寄稿記事

公開
Antibodies
Immunotherapy
Monoclonal Antibodies
Plant Structures
Costs and Cost Analysis

Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody

Akiba, H., Tamura, H., Kiyoshi, M., Yanaka, S., Sugase, K., Caaveiro, J. M. M. & Tsumoto, K., 12 1 2019, : : Scientific reports. 9, 1, 15481.

研究成果: ジャーナルへの寄稿記事

公開
Single-Domain Antibodies
Surface Antigens
Thermodynamics
Antibodies
Epitopes
14 引用 (Scopus)

Structural and thermodynamic basis of epitope binding by neutralizing and nonneutralizing forms of the anti-HIV-1 antibody 4E10

Rujas, E., Gulzar, N., Morante, K., Tsumoto, K., Scott, J. K., Nieva, J. L. & Caaveiro, J. M. M., 1 1 2015, : : Journal of virology. 89, 23, p. 11975-11989 15 p.

研究成果: ジャーナルへの寄稿記事

公開
Complementarity Determining Regions
HIV Antibodies
Human immunodeficiency virus 1
Thermodynamics
neutralization
7 引用 (Scopus)

Structural and thermodynamic characterization of the self-adhesive properties of human P-cadherin

Kudo, S., Caaveiro, J. M. M., Miyafusa, T., Goda, S., Ishii, K., Matsuura, T., Sudou, Y., Kodama, T., Hamakubo, T. & Tsumoto, K., 2012, : : Molecular BioSystems. 8, p. 2050-2053 4 p.

研究成果: ジャーナルへの寄稿記事

Cadherins
Thermodynamics
Adhesives
Divalent Cations
Dimerization
54 引用 (Scopus)

Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI

Kiyoshi, M., Caaveiro, J. M. M., Kawai, T., Tashiro, S., Ide, T., Asaoka, Y., Hatayama, K. & Tsumoto, K., 4 30 2015, : : Nature communications. 6, 6866.

研究成果: ジャーナルへの寄稿記事

公開
Fc Receptors
affinity
Immunoglobulin G
Cell Surface Receptors
Adaptive Immunity
19 引用 (Scopus)

Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface.

Rujas, E., Caaveiro, J. M. M., Partida-Hanon, A., Gulzar, N., Morante, K., Apellaniz, B., García-Porras, M., Bruix, M., Tsumoto, K., Scott, J. K., Jimenez, M. A. & Nieva, J. L., 2016, : : Scientific Reports. 6, 13 p., 38177.

研究成果: ジャーナルへの寄稿記事

公開
HIV-1
Epitopes
Membranes
Complementarity Determining Regions
Peptides
172 引用 (Scopus)

Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)

Shiroishi, M., Kuroki, K., Rasubala, L., Tsumoto, K., Kumagai, I., Kurimoto, E., Kato, K., Kohda, D. & Maenaka, K., 10 31 2006, : : Proceedings of the National Academy of Sciences of the United States of America. 103, 44, p. 16412-16417 6 p.

研究成果: ジャーナルへの寄稿記事

HLA-G Antigens
Leukocytes
HLA-B27 Antigen
Disulfides
Mothers