研究成果 1976 2020

記事
356 引用 (Scopus)

Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20

Abe, Y., Shodai, T., Muto, T., Mihara, K., Torii, H., Nishikawa, S. I., Endo, T. & Kohda, D., 3 3 2000, : : Cell. 100, 5, p. 551-560 10 p.

研究成果: ジャーナルへの寄稿記事

Mitochondrial Proteins
Rats
Aldehyde Dehydrogenase
Peptides
Mitochondria
127 引用 (Scopus)

Structural basis of replication origin recognition by the DnaA protein

Fujikawa, N., Kurumizaka, H., Nureki, O., Terada, T., Shirouzu, M., Katayama, T. & Yokoyama, S., 4 15 2003, : : Nucleic acids research. 31, 8, p. 2077-2086 10 p.

研究成果: ジャーナルへの寄稿記事

Replication Origin
Helix-Turn-Helix Motifs
Hydrogen
DNA
Proteins
34 引用 (Scopus)

Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex: The case of HyHEL-10-HEL

Shiroishi, M., Tsumoto, K., Tanaka, Y., Yokota, A., Nakanishi, T., Kondo, H. & Kumagai, I., 3 2 2007, : : Journal of Biological Chemistry. 282, 9, p. 6783-6791 9 p.

研究成果: ジャーナルへの寄稿記事

Antigen-Antibody Complex
Antigens
Mutation
Antibodies
Antibody Specificity
6 引用 (Scopus)

Structural elucidation of the ceramide moiety of starfish gangliosides by collision-induced dissociation of the sodium ion complex

Inagaki, M., Isobe, R., Miyamoto, T. & Higuchi, R., 1 1 1999, : : Chemical and Pharmaceutical Bulletin. 47, 8, p. 1184-1187 4 p.

研究成果: ジャーナルへの寄稿記事

Starfish
Gangliosides
Ceramides
Sodium
Ions
27 引用 (Scopus)

Structural evidence for entropic contribution of salt bridge formation to a protein antigen-antibody interaction. The case of hen lysozyme-HyHEL-10 Fv complex

Shiroishi, M., Yokota, A., Tsumoto, K., Kondo, H., Nishimiya, Y., Horii, K., Matsushima, M., Ogasahara, K., Yutani, K. & Kumagai, I., 6 22 2001, : : Journal of Biological Chemistry. 276, 25, p. 23042-23050 9 p.

研究成果: ジャーナルへの寄稿記事

Egg White
Muramidase
Salts
Antigens
Antibodies
14 引用 (Scopus)

Structure, synthesis, and biological activity of a C-20 bisacetylenic alcohol from a marine sponge Callyspongia sp.

Shirouzu, T., Watari, K., Ono, M., Koizumi, K., Saiki, I., Tanaka, C., Van Soest, R. W. M. & Miyamoto, T., 7 26 2013, : : Journal of Natural Products. 76, 7, p. 1337-1342 6 p.

研究成果: ジャーナルへの寄稿記事

Callyspongia
Enantiomers
Porifera
Bioactivity
Alcohols
22 引用 (Scopus)

Structure and cytotoxicity of steroidal glycosides from Allium schoenoprasum

Timité, G., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., 4 1 2013, : : Phytochemistry. 88, p. 61-66 6 p.

研究成果: ジャーナルへの寄稿記事

Chive
Spirostans
Allium schoenoprasum
steroid saponins
glycols
75 引用 (Scopus)

Structure and function of DnaA N-terminal domains: Specific sites and mechanisms in inter-DnaA interaction and in DnaB helicase loading on oriC

Abe, Y., Jo, T., Matsuda, Y., Matsunaga, C., Katayama, T. & Ueda, T., 6 15 2007, : : Journal of Biological Chemistry. 282, 24, p. 17816-17827 12 p.

研究成果: ジャーナルへの寄稿記事

DnaB Helicases
Dimerization
Single-Stranded DNA
Nuclear magnetic resonance
DNA
45 引用 (Scopus)

Structure and function of Δ1-tetrahydrocannabinolic acid (THCA) synthase, the enzyme controlling the psychoactivity of Cannabis sativa

Shoyama, Y., Tamada, T., Kurihara, K., Takeuchi, A., Taura, F., Arai, S., Blaber, M., Shoyama, Y., Morimoto, S. & Kuroki, R., 10 12 2012, : : Journal of Molecular Biology. 423, 1, p. 96-105 10 p.

研究成果: ジャーナルへの寄稿記事

Cannabis
Acids
Enzymes
Flavin-Adenine Dinucleotide
Catalysis
7 引用 (Scopus)

Structure and mechanism of the primosome protein DnaT-functional structures for homotrimerization, dissociation of ssDNA from the PriB·ssDNA complex, and formation of the DnaT·ssDNA complex

Fujiyama, S., Abe, Y., Tani, J., Urabe, M., Sato, K., Aramaki, T., Katayama, T. & Ueda, T., 12 2014, : : FEBS Journal. 281, 23, p. 5356-5370 15 p.

研究成果: ジャーナルへの寄稿記事

Escherichia coli
Proteolysis
Klebsiella pneumoniae
Histidine
Nuclear magnetic resonance spectroscopy
9 引用 (Scopus)

Structure determination of the major component of the starfish ganglioside molecular species LG-2 by tandem mass spectrometry

Higuchi, R., Matsumoto, S., Isobe, R. & Miyamoto, T., 8 14 1995, : : Tetrahedron. 51, 33, p. 8961-8968 8 p.

研究成果: ジャーナルへの寄稿記事

Starfish
Gangliosides
Tandem Mass Spectrometry
Mass spectrometry
Positive ions
10 引用 (Scopus)

Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum

Lacaille-Dubois, M. A., Timité, G., Mitaine-Offer, A. C., Miyamoto, T., Ramezani, M., Rustaiyan, A., Mirjolet, J. F. & Duchamp, O., 5 1 2010, : : Magnetic Resonance in Chemistry. 48, 5, p. 370-374 5 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
Saponins
Galactose
Acids
Cytotoxicity
2 引用 (Scopus)

Structure–function analyses of a stereotypic rheumatoid factor unravel the structural basis for germline-encoded antibody autoreactivity

Shiroishi, M., Ito, Y., Shimokawa, K., Lee, J. M., Kusakabe, T. & Ueda, T., 1 1 2018, : : Journal of Biological Chemistry. 293, 18, p. 7008-7016 9 p.

研究成果: ジャーナルへの寄稿記事

Rheumatoid Factor
Antibodies
Complementarity Determining Regions
Hematologic Diseases
Immunoglobulin G
32 引用 (Scopus)

Structure of a new neuritogenic-active ganglioside from the sea cucumber Stichopus japonicus

Kaneko, M., Kisa, F., Yamada, K., Miyamoto, T. & Higuchi, R., 1 1 2003, : : European Journal of Organic Chemistry. 6, p. 1004-1008 5 p.

研究成果: ジャーナルへの寄稿記事

Gangliosides
carbohydrates
sugars
chloroform
acetic acid
19 引用 (Scopus)

Structure of a novel multidrug resistance modulator, irciniasulfonic acid, isolated from a marine sponge, Ircinia sp.

Kawakami, A., Miyamoto, T., Higuchi, R., Uchiumi, T., Kuwano, M. & Van Soest, R. W. M., 5 7 2001, : : Tetrahedron Letters. 42, 19, p. 3335-3337 3 p.

研究成果: ジャーナルへの寄稿記事

Porifera
Multiple Drug Resistance
Modulators
Acids
Isethionic Acid
542 引用 (Scopus)

Structure of the human histamine H 1 receptor complex with doxepin

Shimamura, T., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Han, G. W., Kobayashi, T., Stevens, R. C. & Iwata, S., 7 7 2011, : : Nature. 475, 7354, p. 65-72 8 p.

研究成果: ジャーナルへの寄稿記事

Doxepin
Histamine
Anions
Hypersensitivity
Biogenic Amines
538 引用 (Scopus)

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist

Haga, K., Kruse, A. C., Asada, H., Yurugi-Kobayashi, T., Shiroishi, M., Zhang, C., Weis, W. I., Okada, T., Kobilka, B. K., Haga, T. & Kobayashi, T., 2 23 2012, : : Nature. 482, 7386, p. 547-551 5 p.

研究成果: ジャーナルへの寄稿記事

Muscarinic Receptors
Ligands
Acetylcholine
G Protein-Coupled Inwardly-Rectifying Potassium Channels
Allosteric Regulation
34 引用 (Scopus)

Structure of the Membrane Domain of Human Erythrocyte Anion Exchanger 1 Revealed by Electron Crystallography

Yamaguchi, T., Ikeda, Y., Abe, Y., Kuma, H., Kang, D., Hamasaki, N. & Hirai, T., 3 19 2010, : : Journal of Molecular Biology. 397, 1, p. 179-189 11 p.

研究成果: ジャーナルへの寄稿記事

Erythrocyte Anion Exchange Protein 1
Crystallography
Electrons
Membranes
Antiporters
31 引用 (Scopus)

Structures of four new triterpenoid oligoglycosides: DS-penaustrosides A, B, C, and D from the sea cucumber pentacta australis

Miyamoto, T., Togawa, K., Higuchi, R., Komori, T. & Sasaki, T., 7 1 1992, : : Journal of Natural Products. 55, 7, p. 940-946 7 p.

研究成果: ジャーナルへの寄稿記事

Sea Cucumbers
Glycosides
9 引用 (Scopus)

Structures of sugar chains of a p-nitrophenyl acetate-hydrolyzing esterase from the microsomes of rat liver

Natsuka, S., Himeno, M., Hase, S., Ito, H., Ueda, T., Kato, K. & Ikenaka, T., 1 1 1988, : : Journal of biochemistry. 103, 6, p. 986-991 6 p.

研究成果: ジャーナルへの寄稿記事

Acetylesterase
Liver Microsomes
Esterases
Sugars
Liver
8 引用 (Scopus)
Strychnine
Glucuronosyltransferase
Phenobarbital
Cytochrome P-450 Enzyme System
Hydroxylation
9 引用 (Scopus)

Studies on lymphangiogenesis inhibitors from Korean and Japanese crude drugs

Jeong, D., Watari, K., Shirouzu, T., Ono, M., Koizumi, K., Saiki, I., Kim, Y. C., Tanaka, C., Higuchi, R. & Miyamoto, T., 1 1 2013, : : Biological and Pharmaceutical Bulletin. 36, 1, p. 152-157 6 p.

研究成果: ジャーナルへの寄稿記事

Lymphangiogenesis
Pharmaceutical Preparations
Neoplasms
7-hydroxycoumarin
Endothelial Cells
5 引用 (Scopus)
nucleosides
eggs
Nucleosides
esters
ethers
17 引用 (Scopus)
Hares
Stearates
Aplysia
Cholesterol Esters
Palmitates
14 引用 (Scopus)

Studies on the constituents of marine opisthobranchia, IV. Two new polyhalogenated monoterpenes from the sea hare Aplysia kurodai

Miyamoto, T., Higuchi, R., Marubayashi, N. & Komori, T., 1 1 1988, : : Liebigs Annalen der Chemie. 1988, 12, p. 1191-1193 3 p.

研究成果: ジャーナルへの寄稿記事

mollusks
Monoterpenes
4 引用 (Scopus)

Studies on the αL-iduronidase activity of β-glucuronidase preparations from bovine liver, rat liver, and rat preputial gland

Kosaka, H., Isemura, M., Ono, T., Nishimura, Y. & Kato, K., 7 1 1980, : : Journal of biochemistry. 88, 1, p. 69-75 7 p.

研究成果: ジャーナルへの寄稿記事

Iduronidase
Glucuronidase
Liver
Rats
Hydrolysis

Study of the Physiological Role of 3, 3′, 4, 4′, 5-Pentachlorobiphenyl Inducible 54 KDa Protein in Cytosol of Rat Liver

Ishida, T., Hatsumura, M., Tasaki, K., Fukuda, A., Yoshioka, Y., Ishii, Y. & Oguri, K., 1 1 1998, : : Japanese Journal of Toxicology and Environmental Health. 44, 1

研究成果: ジャーナルへの寄稿記事

3,4,5,3',4'-pentachlorobiphenyl
Cytosol
Liver
Proteins
16 引用 (Scopus)

Sulfated lupane triterpene derivatives and a flavone C-glycoside from Gypsophila repens

Elbandy, M., Miyamoto, T. & Lacaille-Dubois, M. A., 5 1 2007, : : Chemical and Pharmaceutical Bulletin. 55, 5, p. 808-811 4 p.

研究成果: ジャーナルへの寄稿記事

flavone
Triterpenes
Derivatives
Esters
Luteolin
14 引用 (Scopus)

Suppression of carbonic anhydrase III in rat liver by a dioxin-related toxic compound, coplanar polychlorinated biphenyl, 3,3',4,4',5-pentachlorobiphenyl

Ikeda, M., Ishii, Y., Kato, H., Akazawa, D., Hatsumura, M., Ishida, T., Matsusue, K., Yamada, H. & Oguri, K., 8 1 2000, : : Archives of Biochemistry and Biophysics. 380, 1, p. 159-164 6 p.

研究成果: ジャーナルへの寄稿記事

3,4,5,3',4'-pentachlorobiphenyl
Carbonic Anhydrase III
Dioxins
Poisons
Polychlorinated Biphenyls
10 引用 (Scopus)

Suppression of carbonic anhydrase III mRNA level by an aryl hydrocarbon receptor ligand in primary cultured hepatocytes of rat

Ishii, Y., Akazawa, D., Aoki, Y., Yamada, H. & Oguri, K., 6 1 2005, : : Biological and Pharmaceutical Bulletin. 28, 6, p. 1087-1090 4 p.

研究成果: ジャーナルへの寄稿記事

Carbonic Anhydrase III
Aryl Hydrocarbon Receptors
Hepatocytes
Ligands
Messenger RNA
12 引用 (Scopus)
Cytochrome P-450 CYP3A
Glucuronosyltransferase
Proteins
Calnexin
NADPH-Ferrihemoprotein Reductase
26 引用 (Scopus)

Suppression of fetal testicular cytochrome P450 17 by maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: A mechanism involving an initial effect on gonadotropin synthesis in the pituitary

Taketoh, J., Mutoh, J., Takeda, T., Ogishima, T., Takeda, S., Ishii, Y., Ishida, T. & Yamada, H., 3 13 2007, : : Life Sciences. 80, 14, p. 1259-1267 9 p.

研究成果: ジャーナルへの寄稿記事

Maternal Exposure
Gonadotropins
Cytochrome P-450 Enzyme System
Luteinizing Hormone
Multifetal Pregnancy Reduction
12 引用 (Scopus)

Suppression of stress proteins, GRP78, GRP94, calreticulin and calnexin in liver endoplasmic reticulum of rat treated with a highly toxic coplanar PCB

Yoshioka, Y., Ishii, Y., Ishida, T., Yamada, H., Oguri, K. & Motojima, K., 1 1 2001, : : Fukuoka igaku zasshi = Hukuoka acta medica. 92, 5, p. 201-216 16 p.

研究成果: ジャーナルへの寄稿記事

Calnexin
Calreticulin
Poisons
Polychlorinated Biphenyls
Heat-Shock Proteins
4 引用 (Scopus)

Suppression of stress proteins in endoplasmic reticulum in liver cytosol of rats treated with a highly toxic coplanar PCB

Tasaki, K., Ishii, Y., Ishida, T. & Oguri, K., 9 3 1999, : : Fukuoka Acta Medica. 90, 5, p. 251-258 8 p.

研究成果: ジャーナルへの寄稿記事

Poisons
Polychlorinated Biphenyls
Heat-Shock Proteins
Endoplasmic Reticulum
Cytosol
21 引用 (Scopus)

Suppressors of DnaAATP imposed overinitiation in Escherichia coli

Charbon, G., Riber, L., Cohen, M., Skovgaard, O., Fujimitsu, K., Katayama, T. & Løbner-Olesen, A., 2 1 2011, : : Molecular Microbiology. 79, 4, p. 914-928 15 p.

研究成果: ジャーナルへの寄稿記事

Escherichia coli
Genetic Suppression
Chromosomes
Binding Sites
Rejuvenation
11 引用 (Scopus)

Survey of solasodine-type glycoalkaloids by western blotting and ELISA using anti-solamargine monoclonal antibody

Putalun, W., Tanaka, H., Yahara, S., Lhieochaiphan, S. & Shoyama, Y., 1 2000, : : Biological and Pharmaceutical Bulletin. 23, 1, p. 72-75 4 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
Solanum
Western Blotting
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
18 引用 (Scopus)

Synthesis and absolute stereochemistry of the acyl moiety of quillajasaponins

Zhu, X., Yu, B., Hui, Y., Higuchi, R., Kusano, T. & Miyamoto, T., 1 29 2000, : : Tetrahedron Letters. 41, 5, p. 717-719 3 p.

研究成果: ジャーナルへの寄稿記事

Immunologic Adjuvants
Stereochemistry
octanoic acid
1 引用 (Scopus)

Synthesis and properties of a mercapto[15]annulenone: A 14π diatropic annulene triply characterised by a fast chemical exchange, tautomerisation, and cis-trans-isomerisation

Ogawa, H., Yoshikawa, M., Tanaka, H., Imoto, T., Miyamoto, I., Kato, H., Taniguchi, Y., Nogami, Y. & Koga, T., 1 1 1989, : : Journal of the Chemical Society, Chemical Communications. 8, p. 505-507 3 p.

研究成果: ジャーナルへの寄稿記事

Isomerization
Ion exchange
annulenone
1 引用 (Scopus)

Synthesis of 12- O-Mono- and Diglycosyl-oxystearates, a New Class of Agonists for the C-type Lectin Receptor Mincle

Van Huy, L., Tanaka, C., Imai, T., Yamasaki, S. & Miyamoto, T., 10 1 2019, : : ACS Medicinal Chemistry Letters. 10, 1, p. 44-49 6 p.

研究成果: ジャーナルへの寄稿記事

C-Type Lectins
Macrophages
NFATC Transcription Factors
Structure-Activity Relationship
Green Fluorescent Proteins
19 引用 (Scopus)

Synthesis of a hematoside analog containing phytosphingosine and α-hydroxfatty acid

Sugata, T., Kan, Y., Nagaregawa, Y., Miyamoto, T. & Higuchi, R., 1 1 1997, : : Journal of Carbohydrate Chemistry. 16, 6, p. 917-925 9 p.

研究成果: ジャーナルへの寄稿記事

phytosphingosine
G(M3) Ganglioside
Acids
Derivatives
Glycosylation
14 引用 (Scopus)

Synthesis of simple sea cucumber ganglioside analogs

Higuchi, R., Mori, T., Sugata, T., Yamada, K. & Miyamoto, T., 11 1 1999, : : European Journal of Organic Chemistry. 11, p. 3175-3178 4 p.

研究成果: ジャーナルへの寄稿記事

Gangliosides
analogs
N-Acetylneuraminic Acid
synthesis
glucosides
4 引用 (Scopus)

Synthetic studies on the natural multidrug resistance modulator, irciniasulfonic acid B

Emura, C., Higuchi, R. & Miyamoto, T., 2010, : : Chemistry Letters. 39, 9, p. 1002-1003 2 p.

研究成果: ジャーナルへの寄稿記事

Modulators
Acids
furan
7alpha-dihydroxy-3-oxopregn-4-en-21-oate methyl-1alpha
2-nonanone
38 引用 (Scopus)

Tannins and Related Compounds. L.1) Structures of Proanthocyanidin A-l and Related Compounds

Nonaka, G. I., Morimoto, S., Nishioka, I., Kinjo, J. E. & Nohara, T., 1 1 1987, : : Chemical and Pharmaceutical Bulletin. 35, 1, p. 149-155 7 p.

研究成果: ジャーナルへの寄稿記事

Tannins
Proanthocyanidins
proanthocyanidin
proanthocyanidin A1
53 引用 (Scopus)

Tannins and Related Compounds. LIX.1)Aesculitannins, Novel Proanthocyanidins with Doubly-Bonded Structures from Aesculus hippocastanum L.

Morimoto, S., Nonaka, G. I. & Nishioka, I., 1 1 1987, : : Chemical and Pharmaceutical Bulletin. 35, 12, p. 4717-4729 13 p.

研究成果: ジャーナルへの寄稿記事

Aesculus
Proanthocyanidins
Catechin
Tannins
varespladib methyl
31 引用 (Scopus)
Vaccinium vitis-idaea
Proanthocyanidins
Catechin
Tannins
Ericaceae
50 引用 (Scopus)

Tannins and Related Compounds. LXI.1) Isolation and Structures of Novel Bi- and Triflavanoids from the Leaves of Cassia fistula L.

Morimoto, S., Nonaka, G. I., Chen, R. F. & Nishioka, I., 1 1 1988, : : Chemical and Pharmaceutical Bulletin. 36, 1, p. 39-47 9 p.

研究成果: ジャーナルへの寄稿記事

Cassia
Tannins
Proanthocyanidins
Catechin
Glucosides
87 引用 (Scopus)
Catechin
Tannins
30 引用 (Scopus)

Tannins and Related Compounds. Proanthocyanidins with a Doubly Linked Unit from the Root Bark of Cinnamomum sieboldii Meisner

Morimoto, S., Nonaka, G. I. & Nishioka, I., 1 1 1985, : : Chemical and Pharmaceutical Bulletin. 33, 10, p. 4338-4345 8 p.

研究成果: ジャーナルへの寄稿記事

Cinnamomum
Proanthocyanidins
Catechin
Tannins
Lauraceae
61 引用 (Scopus)
Lindera
Cinnamomum aromaticum
Catechin
Tannins
Cinnamomum
29 引用 (Scopus)
Cinnamomum aromaticum
Proanthocyanidins
Tannins
Glucosides
varespladib methyl