研究成果 1976 2020

記事
80 引用 (Scopus)

Testing geometrical discrimination within an enzyme active site: Constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole

Sigala, P. A., Kraut, D., Caaveiro, J. M. M., Pybus, B., Ruben, E., Ringe, D., Petsko, G. A. & Herschlag, D., 2008, : : Journal of the American Chemical Society. 130, p. 13696-13708 13 p.

研究成果: ジャーナルへの寄稿記事

Ketosteroids
Isomerases
Hydrogen Bonding
Catalytic Domain
Hydrogen bonds
88 引用 (Scopus)

Tetrahydrocannabinolic acid synthase, the enzyme controlling marijuana psychoactivity, is secreted into the storage cavity of the glandular trichomes

Sirikantaramas, S., Taura, F., Tanaka, Y., Ishikawa, Y., Morimoto, S. & Shoyama, Y., 9 1 2005, : : Plant and Cell Physiology. 46, 9, p. 1578-1582 5 p.

研究成果: ジャーナルへの寄稿記事

Trichomes
Cannabis sativa
Cannabis
trichomes
Acids
11 引用 (Scopus)

Tetrapterosides A and B, two new oleanane-type saponins from Tetrapleura tetraptera

Noté, O. P., Mitaine-Offer, A. C., Miyamoto, T., Paululat, T., Pegnyemb, D. E. & Lacaille-Dubois, M. A., 3 1 2009, : : Magnetic Resonance in Chemistry. 47, 3, p. 277-282 6 p.

研究成果: ジャーナルへの寄稿記事

Saponins
Acids
Mass spectrometry
Nuclear magnetic resonance
Experiments
2 引用 (Scopus)

The accelerated excretion of 2,3,4,7,8-pentachlorodibenzofuran by Cholebine

Ishida, T., Sakai, Y., Ishii, Y., Furue, M. & Yamada, H., 1 1 2009, : : Fukuoka igaku zasshi = Hukuoka acta medica. 100, 5, p. 210-216 7 p.

研究成果: ジャーナルへの寄稿記事

Dioxins
2,3,4,7,8-pentachlorodibenzofuran
cholebine
Polychlorinated Biphenyls
Brain
6 引用 (Scopus)

The active constituents from Gualou-xiebai-baijiu-tang part I: Active saponins

He, X. J., Qiu, F., Shoyama, Y., Tanaka, H. & Yao, X. S., 2002, : : Journal of Asian Natural Products Research. 4, 3, p. 189-196 8 p.

研究成果: ジャーナルへの寄稿記事

steroid saponins
Saponins
saponins
Galactose
glycols
15 引用 (Scopus)

The Arg fingers of key DnaA protomers are oriented inward within the replication origin oriC and stimulate DnaA subcomplexes in the initiation complex

Noguchi, Y., Sakiyama, Y., Kawakami, H. & Katayama, T., 8 14 2015, : : Journal of Biological Chemistry. 290, 33, p. 20295-20312 18 p.

研究成果: ジャーナルへの寄稿記事

Replication Origin
Protein Subunits
Fingers
DnaB Helicases
Adenosine Triphosphate

The aryl hydrocarbon receptor is indispensable for dioxin-induced defects in sexually-dimorphic behaviors due to the reduction in fetal steroidogenesis of the pituitary-gonadal axis in rats

Hattori, Y., Takeda, T., Nakamura, A., Nishida, K., Shioji, Y., Fukumitsu, H., Yamada, H. & Ishii, Y., 8 1 2018, : : Biochemical Pharmacology. 154, p. 213-221 9 p.

研究成果: ジャーナルへの寄稿記事

Multifetal Pregnancy Reduction
Aryl Hydrocarbon Receptors
Dioxins
Rats
Defects
28 引用 (Scopus)

The atomic structure of the HIV-1 gp41 transmembrane domain and its connection to the immunogenic membrane-proximal external region

Apellaniz, B., Rujas, E., Serrano, S., Morante, K., Tsumoto, K., Caaveiro, J. M. M., Jimenez, M. A. & Nieva, J. L., 2015, : : Journal of Biological Chemistry. p. 12999-13015 17 p.

研究成果: ジャーナルへの寄稿記事

HIV-1
Membranes
Fusion reactions
Anchors
Vaccines
8 引用 (Scopus)

The Cdc45/RecJ-like protein forms a complex with GINS and MCM, and is important for DNA replication in Thermococcus kodakarensis

Nagata, M., Ishino, S., Yamagami, T., Ogino, H., Simons, J. R., Kanai, T., Atomi, H. & Ishino, Y., 10 1 2017, : : Nucleic acids research. 45, 18, p. 10693-10705 13 p.

研究成果: ジャーナルへの寄稿記事

Thermococcus
DNA Replication
Maintenance
Proteins
DNA Helicases
3 引用 (Scopus)

The DnaA AAA+ Domain His136 residue directs DnaB replicative helicase to the unwound region of the replication origin, oriC

Sakiyama, Y., Nishimura, M., Hayashi, C., Akama, Y., Ozaki, S. & Katayama, T., 8 31 2018, : : Frontiers in Microbiology. 9, AUG, 2017.

研究成果: ジャーナルへの寄稿記事

DnaB Helicases
Replication Origin
Nucleoproteins
Single-Stranded DNA
Protein Subunits
24 引用 (Scopus)

The DnaA homolog of the hyperthermophilic eubacterium Thermotoga maritima an open complex with a minimal 149-bp origin region in an ATP-dependent manner

Ozaki, S., Fujimitsu, K., Kurumizaka, H. & Katayama, T., 4 1 2006, : : Genes to Cells. 11, 4, p. 425-438 14 p.

研究成果: ジャーナルへの寄稿記事

Thermotoga maritima
Eubacterium
Adenosine Triphosphate
Adenosine Diphosphate
AT Rich Sequence
13 引用 (Scopus)

The DnaA N-terminal domain interacts with Hda to facilitate replicase clamp-mediated inactivation of DnaA

Su'etsugu, M., Harada, Y., Keyamura, K., Matsunaga, C., Kasho, K., Abe, Y., Ueda, T. & Katayama, T., 12 1 2013, : : Environmental Microbiology. 15, 12, p. 3183-3195 13 p.

研究成果: ジャーナルへの寄稿記事

inactivation
Adenosine Triphosphate
hydrolysis
DNA
Hydrolysis
40 引用 (Scopus)

The E1 Protein of Human Papillomavirus Type 16 Is Dispensable for Maintenance Replication of the Viral Genome

Egawa, N., Nakahara, T., Ohno, S. I., Narisawa-Saito, M., Yugawa, T., Fujita, M., Yamato, K., Natori, Y. & Kiyono, T., 3 1 2012, : : Journal of virology. 86, 6, p. 3276-3283 8 p.

研究成果: ジャーナルへの寄稿記事

Papillomaviridae
Viral Genome
virus replication
Human papillomavirus 16
Maintenance

The Effect of Maternal Exposure to Dioxins on the Level of Thyroid Hormone in Developing Pups

Hattori, Y., Takeda, T., Taura, J., Kuroki, H., Ishii, Y. & Yamada, H., 5 1 2015, : : Fukuoka igaku zasshi = Hukuoka acta medica. 106, 5, p. 127-134 8 p.

研究成果: ジャーナルへの寄稿記事

Maternal Exposure
Dioxins
Thyroid Hormones
Thyroxine
Thyrotropin
4 引用 (Scopus)

The effect of varying the peptide linker length in a single chain variable fragment antibody against wogonin glucuronide

Paudel, M. K., Sakamoto, S., Van Huy, L., Tanaka, H., Miyamoto, T. & Morimoto, S., 6 10 2017, : : Journal of Biotechnology. 251, p. 47-52 6 p.

研究成果: ジャーナルへの寄稿記事

Single-Chain Antibodies
Glucuronides
Antibodies
Peptides
Assays
30 引用 (Scopus)

The EGFR inhibitor gefitinib suppresses ligand-stimulated endocytosis of EGFR via the early/late endocytic pathway in non-small cell lung cancer cell lines

Nishimura, Y., Bereczky, B. & Ono, M., 5 1 2007, : : Histochemistry and Cell Biology. 127, 5, p. 541-553 13 p.

研究成果: ジャーナルへの寄稿記事

Endocytosis
Non-Small Cell Lung Carcinoma
Ligands
Endosomes
Cell Line
7 引用 (Scopus)
Prophages
Multigene Family
Escherichia coli
Hydroxyurea
Proteins
29 引用 (Scopus)

The exceptionally tight affinity of DnaA for ATP/ADP requires a unique aspartic acid residue in the AAA+ sensor 1 motif

Kawakami, H., Ozaki, S., Suzuki, S., Nakamura, K., Senriuchi, T., Su'etsugu, M., Fujimitsu, K. & Katayama, T., 12 1 2006, : : Molecular Microbiology. 62, 5, p. 1310-1324 15 p.

研究成果: ジャーナルへの寄稿記事

Aspartic Acid
Adenosine Diphosphate
Adenosine Triphosphate
Viperidae
Proteins
13 引用 (Scopus)

The functional role of arginine 901 at the C-terminus of the human anion transporter band 3 protein

Takazaki, S., Abe, Y., Kang, D., Li, C., Jin, X., Ueda, T. & Hamasaki, N., 5 1 2006, : : Journal of biochemistry. 139, 5, p. 903-912 10 p.

研究成果: ジャーナルへの寄稿記事

Erythrocyte Anion Exchange Protein 1
Anions
Arginine
Membranes
Acids
128 引用 (Scopus)

The gene controlling marijuana psychoactivity. Molecular cloning and heterologous expression of Δ1-tetrahydrocannabinolic acid synthase from Cannabis sativa L.

Sirikantaramas, S., Morimoto, S., Shoyama, Y., Ishikawa, Y., Wada, Y., Shoyama, Y. & Taura, F., 9 17 2004, : : Journal of Biological Chemistry. 279, 38, p. 39767-39774 8 p.

研究成果: ジャーナルへの寄稿記事

Cloning
Molecular Cloning
Cannabis
Genes
Flavin-Adenine Dinucleotide
52 引用 (Scopus)

The Histone Deacetylases Sir2 and Rpd3 Act on Ribosomal DNA to Control the Replication Program in Budding Yeast

Yoshida, K., Bacal, J., Desmarais, D., Padioleau, I., Tsaponina, O., Chabes, A., Pantesco, V., Dubois, E., Parrinello, H., Skrzypczak, M., Ginalski, K., Lengronne, A. & Pasero, P., 5 22 2014, : : Molecular Cell. 54, 4, p. 691-697 7 p.

研究成果: ジャーナルへの寄稿記事

Saccharomycetales
Histone Deacetylases
Ribosomal DNA
Peptide Initiation Factors
Nucleic Acid Repetitive Sequences
10 引用 (Scopus)

The induction of hepatic selenium-binding protein by aryl hydrocarbon (Ah)-receptor ligands in rats

Ishida, T., Ishii, Y., Yamada, H. & Oguri, K., 2 1 2002, : : Journal of Health Science. 48, 1, p. 62-68 7 p.

研究成果: ジャーナルへの寄稿記事

Selenium-Binding Proteins
Aryl Hydrocarbon Receptors
Rats
Ligands
Liver
248 引用 (Scopus)

The initiator function of DnaA protein is negatively regulated by the sliding clamp of the E. coli Chromosomal replicase

Katayama, T., Kubota, T., Kurokawa, K., Crooke, E. & Sekimizu, K., 7 10 1998, : : Cell. 94, 1, p. 61-71 11 p.

研究成果: ジャーナルへの寄稿記事

DNA Polymerase III
Clamping devices
Adenosine Diphosphate
Escherichia coli
DNA
91 引用 (Scopus)

The interaction of DiaA and DnaA regulates the replication cycle in E. coli by directly promoting ATP-DnaA-specific initiation complexes

Keyamura, K., Fujikawa, N., Ishida, T., Ozaki, S., Su'etsugu, M., Fujimitsu, K., Kagawa, W., Yokoyama, S., Kurumizaka, H. & Katayama, T., 8 15 2007, : : Genes and Development. 21, 16, p. 2083-2099 17 p.

研究成果: ジャーナルへの寄稿記事

Adenosine Triphosphate
Escherichia coli
Adenosine Diphosphate
Cell Cycle
Mutant Proteins

The isolation of new pore-forming toxins from the sea anemone actinia fragacea provides insights into the mechanisms of actinoporin evolution

Morante, K., Bellomio, A., Viguera, A. R., González-Mañas, J. M., Tsumoto, K. & Caaveiro, J. M. M., 7 10 2019, : : Toxins. 11, 7, toxins11070401.

研究成果: ジャーナルへの寄稿記事

公開
Actinium
Sea Anemones
Proteins
Species Specificity
Protein Stability
20 引用 (Scopus)

The long-term immunosuppressive effects of disulfide-linked HLA-G dimer in mice with collagen-induced arthritis

Kuroki, K., Hirose, K., Okabe, Y., Fukunaga, Y., Takahashi, A., Shiroishi, M., Kajikawa, M., Tabata, S., Nakamura, S., Takai, T., Koyanagi, S., Ohdo, S. & Maenaka, K., 4 1 2013, : : Human Immunology. 74, 4, p. 433-438 6 p.

研究成果: ジャーナルへの寄稿記事

HLA-G Antigens
Experimental Arthritis
Immunosuppressive Agents
Disulfides
Foot Joints
16 引用 (Scopus)

The molecular weight ratio of monomethoxypolyethylene glycol (mPEG) to protein determines the immunotolerogenicity of mPEG proteins

So, T., Ito, H. O., Tsujihata, Y., Hirata, M., Ueda, T. & Imoto, T., 1 1 1999, : : Protein Engineering. 12, 8, p. 701-705 5 p.

研究成果: ジャーナルへの寄稿記事

Glycols
Molecular Weight
Molecular weight
Proteins
gamma-Globulins
17 引用 (Scopus)

The NH2-terminal transmembrane and lumenal domains of LGP85 are needed for the formation of enlarged endosomes/lysosomes

Kuronita, T., Hatano, T., Furuyama, A., Hirota, Y., Masuyama, N., Saftig, P., Himeno, M., Fujita, H. & Tanaka, Y., 10 1 2005, : : Traffic. 6, 10, p. 895-906 12 p.

研究成果: ジャーナルへの寄稿記事

Scavenger Receptors
Endosomes
Lysosomes
Lysosome-Associated Membrane Glycoproteins
CD36 Antigens
19 引用 (Scopus)

The nucleoid protein H-NS facilitates chromosome DNA replication in Escherichia coli dnaA mutants

Katayama, T., Takata, M. & Sekimizu, K., 1 1 1996, : : Journal of bacteriology. 178, 19, p. 5790-5792 3 p.

研究成果: ジャーナルへの寄稿記事

DNA Replication
Chromosomes
Escherichia coli
Thymine
Proteins
3 引用 (Scopus)
Aryl Hydrocarbon Receptors
Dioxins
Oxidative stress
Quercetin
Heat-Shock Proteins
14 引用 (Scopus)

The possible role of nitric oxide in relaxations and excitatory neuroeffector transmission in the cat airway

Tanaka, H., Jing, L., Takahashi, S. & Ito, Y., 6 15 1996, : : Journal of Physiology. 493, 3, p. 785-791 7 p.

研究成果: ジャーナルへの寄稿記事

Nitric Oxide
Cats
NG-Nitroarginine Methyl Ester
Electric Stimulation
Bronchi
36 引用 (Scopus)

The primary structures and properties of non‐stomach lysozymes of sheep and cow, and implication for functional divergence of lysozyme

ITO, Y., YAMADA, H., NAKAMURA, M., YOSHIKAWA, A., Ueda, T. & IMOTO, T., 1 1 1993, : : European Journal of Biochemistry. 213, 2, p. 649-658 10 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Sheep
Kidney
Stomach
Ruminant Stomach
53 引用 (Scopus)

The relationship between the aggregational state of the amyloid-β peptides and free radical generation by the peptides

Monji, A., Utsumi, H., Ueda, T., Imoto, T., Yoshida, I., Hashioka, S., Tashiro, K. I. & Tashiro, N., 7 5 2001, : : Journal of Neurochemistry. 77, 6, p. 1425-1432 8 p.

研究成果: ジャーナルへの寄稿記事

Amyloid
Free Radicals
Phosphates
Peptides
Buffers
14 引用 (Scopus)
Protein Unfolding
Thermodynamics
Derivatives
Kinetics
Digestion
21 引用 (Scopus)

Thermodynamic consequences of grafting enhanced affinity toward the mutated antigen onto an antibody. The case of anti-lysozyme antibody HyHEL-10

Nishimiya, Y., Tsumoto, K., Shiroishi, M., Yutani, K. & Kumagai, I., 4 28 2000, : : Journal of Biological Chemistry. 275, 17, p. 12813-12820 8 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Thermodynamics
Anti-Idiotypic Antibodies
Antigens
Antibodies
3 引用 (Scopus)

Thermostability of doubly glycosylated recombinant lysozyme

Hashimoto, Y., Munemura, O., Masumoto, K., Ueda, T. & Imoto, T., 11 21 2001, : : Biological and Pharmaceutical Bulletin. 24, 10, p. 1102-1107 6 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Glycosylation
Yeasts
Peptide Mapping
Differential Scanning Calorimetry

The Role of a Rat Liver Cytosolic 54 kDa Protein That Is Inducible by Dioxins

Ishida, T., Maji, D., Yoshioka, Y., Ishii, Y. & Oguri, K., 1 1 1999, : : Journal of Health Science. 45, 1, 1 p.

研究成果: ジャーナルへの寄稿記事

Dioxins
Liver
Rats
Proteins
49 引用 (Scopus)

The role of hydrogen bonding via interfacial water molecules in antigen-antibody complexation: The HyHEL-10-HEL interaction

Yokota, A., Tsumoto, K., Shiroishi, M., Kondo, H. & Kumagai, I., 2 14 2003, : : Journal of Biological Chemistry. 278, 7, p. 5410-5418 9 p.

研究成果: ジャーナルへの寄稿記事

Egg White
Hydrogen Bonding
Muramidase
Complexation
Hydrogen bonds
21 引用 (Scopus)

The role of net charge on the renaturation of reduced lysozyme by the sulfhydryl-disulfide interchange reaction

Maeda, Y., Ueda, T., Yamada, H. & Imoto, T., 10 1 1994, : : Protein Engineering, Design and Selection. 7, 10, p. 1249-1254 6 p.

研究成果: ジャーナルへの寄稿記事

Interchanges
Muramidase
Disulfides
Enzymes
Agglomeration
2 引用 (Scopus)

The structure of an archaeal β-glucosaminidase provides insight into glycoside hydrolase evolution

Mine, S., Watanabe, M., Kamachi, S., Abe, Y. & Ueda, T., 3 24 2017, : : Journal of Biological Chemistry. 292, 12, p. 4996-5006 11 p.

研究成果: ジャーナルへの寄稿記事

Hexosaminidases
Glycoside Hydrolases
Galactosidases
Glucosamine
Catalytic Domain
1 引用 (Scopus)

The structure of hyperthermophilic β-N-acetylglucosaminidase reveals a novel dimer architecture associated with the active site

Mine, S., Kado, Y., Watanabe, M., Fukuda, Y., Abe, Y., Ueda, T., Kawarabayasi, Y., Inoue, T. & Ishikawa, K., 11 1 2014, : : FEBS Journal. 281, 22, p. 5092-5103 12 p.

研究成果: ジャーナルへの寄稿記事

Acetylglucosaminidase
Dimers
Glycoside Hydrolases
Catalytic Domain
Catalysis
17 引用 (Scopus)

The synthesis of rat liver lysosomes: III. chemical composition of microsomal and lysosomal β-glucuronidases purified from rat liver

Himeno, M., Nishimura, Y., Takahashi, K. & Kato, K., 1 1 1978, : : Journal of biochemistry. 83, 2, p. 511-518 8 p.

研究成果: ジャーナルへの寄稿記事

Glucuronidase
Lysosomes
Liver
Rats
N-Acetylneuraminic Acid
16 引用 (Scopus)

Three new acylated triterpene saponins from Acanthophyllum squarrosum

Gaidi, G., Miyamoto, T., Rustaiyan, A. & Lacaille-Dubois, M. A., 8 20 2001, : : Journal of Natural Products. 64, 7, p. 920-924 5 p.

研究成果: ジャーナルへの寄稿記事

Triterpenes
Saponins
Nuclear magnetic resonance
gypsogenin
quillaic acid
19 引用 (Scopus)

Three new cytotoxic sesterterpenoids, inorolide A, B, and C from the nudibranch Chromodoris inornata

Miyamoto, T., Sakamoto, K., Amano, H., Higuchi, R., Komori, T. & Sasaki, T., 9 22 1992, : : Tetrahedron Letters. 33, 39, p. 5811-5814 4 p.

研究成果: ジャーナルへの寄稿記事

X-Rays
Single crystals
X rays
5 引用 (Scopus)

Three new medicagenic acid saponins from Polygala micrantha GUILL. & PERR.

Tabopda, T. K., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Ngadjui, B. T., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., 5 1 2011, : : Helvetica Chimica Acta. 94, 5, p. 914-922 9 p.

研究成果: ジャーナルへの寄稿記事

Polygala
Saponins
Esters
esters
acids
29 引用 (Scopus)

Three new triterpene saponins from two species of Carpolobia

Mitaine-Offer, A. C., Miyamoto, T., Khan, I. A., Delaude, C. & Lacaille-Dubois, M. A., 5 11 2002, : : Journal of Natural Products. 65, 4, p. 553-557 5 p.

研究成果: ジャーナルへの寄稿記事

Triterpenes
Saponins
Esters
Nuclear magnetic resonance
31 引用 (Scopus)

Timely binding of IHF and Fis to DARS2 regulates ATP-DnaA production and replication initiation

Kasho, K., Fujimitsu, K., Matoba, T., Oshima, T. & Katayama, T., 12 1 2014, : : Nucleic acids research. 42, 21, p. 13134-13149 16 p.

研究成果: ジャーナルへの寄稿記事

Adenosine Triphosphate
Adenosine Diphosphate
Cell Cycle
Nucleotides
Regeneration
23 引用 (Scopus)

Tolerance of point substitution of methionine for isoleucine in hen egg white lysozyme

Ohmura, T., Ueda, T., Hashimoto, Y. & Imoto, T., 8 29 2001, : : Protein Engineering. 14, 6, p. 421-425 5 p.

研究成果: ジャーナルへの寄稿記事

Egg White
Isoleucine
Muramidase
Methionine
Substitution reactions
11 引用 (Scopus)

Tolerogenic activity of polyethylene glycol-conjugated lysozyme distinct from that of the native counterpart

Ito, H. O., So, T., Hirata, M., Koga, T., Ueda, T. & Imoto, T., 3 9 1998, : : Immunology. 93, 2, p. 200-207 8 p.

研究成果: ジャーナルへの寄稿記事

Egg White
Muramidase
hen egg lysozyme
Proteins
Antigens
20 引用 (Scopus)

Tor and the Sin3-Rpd3 complex regulate expression of the mitophagy receptor protein Atg32 in yeast

Aihara, M., Jin, X., Kurihara, Y., Yoshida, Y., Matsushima, Y., Oku, M., Hirota, Y., Saigusa, T., Aoki, Y., Uchiumi, T., Yamamoto, T., Sakai, Y., Kang, D. & Kanki, T., 2014, : : Journal of cell science. 127, 14, p. 3184-3196 13 p.

研究成果: ジャーナルへの寄稿記事

Mitochondrial Degradation
Yeasts
Proteins
Pichia
Sirolimus