研究成果 1976 2019

記事
122 引用 (Scopus)

Crocin suppresses tumor necrosis factor-α-induced cell death of neuronally differentiated PC-12 cells

Soeda, S., Ochiai, T., Paopong, L., Tanaka, H., Shoyama, Y. & Shimeno, H., 11 2 2001, : : Life Sciences. 69, 24, p. 2887-2898 12 p.

研究成果: ジャーナルへの寄稿記事

Cell death
Cell Death
Tumor Necrosis Factor-alpha
Daunorubicin
Cytochromes c
7 引用 (Scopus)

Cross-reactivity of various tetrahydrocannabinol metabolites with a monoclonal antibody against tetrahydrocannabinolic acid

Watanabe, K., Matsuda, M., Tateoka, Y., Kimura, T., Matsunaga, T., Tanaka, H., Shoyama, Y. & Yamamoto, I., 1 1 2000, : : Journal of Health Science. 46, 4, p. 310-313 4 p.

研究成果: ジャーナルへの寄稿記事

Dronabinol
Metabolites
Monoclonal Antibodies
Acids
Cannabinoids
92 引用 (Scopus)

Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA

Sun, J., Evrin, C., Samel, S. A., Fernández-Cid, A., Riera, A., Kawakami, H., Stillman, B., Speck, C. & Li, H., 8 1 2013, : : Nature Structural and Molecular Biology. 20, 8, p. 944-951 8 p.

研究成果: ジャーナルへの寄稿記事

Minichromosome Maintenance Proteins
DNA
Replication Protein C
Eukaryota
Adenosine Triphosphatases
1 引用 (Scopus)
X ray analysis
HLA Antigens
Crystallization
Leukocytes
X-Rays
8 引用 (Scopus)

Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa

Taguchi, C., Taura, F., Tamada, T., Shoyama, Y., Shoyama, Y., Tanaka, H., Kuroki, R. & Morimoto, S., 3 13 2008, : : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 64, 3, p. 217-220 4 p.

研究成果: ジャーナルへの寄稿記事

Polyketide Synthases
Cannabis
Crystallization
X-Ray Diffraction
HEPES

Crystallization of Human Erythrocyte Band 3, the anion exchanger, at the International Space Station “KIBO”

Hatae, H., Inaka, K., Okamura, R., Furubayashi, N., Kamo, M., Kobayashi, T., Abe, Y., Iwata, S. & Hamasaki, N., 10 15 2018, : : Analytical Biochemistry. 559, p. 91-93 3 p.

研究成果: ジャーナルへの寄稿記事

Chloride-Bicarbonate Antiporters
Space stations
Crystallization
Blood
Erythrocytes
18 引用 (Scopus)

Crystallization of Δ1-tetrahydrocannabinolic acid (THCA) synthase from Cannabis sativa

Shoyama, Y., Takeuchi, A., Taura, F., Tamada, T., Adachi, M., Kuroki, R., Shoyama, Y. & Morimoto, S., 8 1 2005, : : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 61, 8, p. 799-801 3 p.

研究成果: ジャーナルへの寄稿記事

Cannabis
Crystallization
crystallization
HEPES
acids
157 引用 (Scopus)

Crystal structure-based virtual screening for fragment-like ligands of the human histamine H 1 receptor

De Graaf, C., Kooistra, A. J., Vischer, H. F., Katritch, V., Kuijer, M., Shiroishi, M., Iwata, S., Shimamura, T., Stevens, R. C., De Esch, I. J. P. & Leurs, R., 12 8 2011, : : Journal of Medicinal Chemistry. 54, 23, p. 8195-8206 12 p.

研究成果: ジャーナルへの寄稿記事

Histamine
G-Protein-Coupled Receptors
Ligands
Computer Simulation
Molecular Docking Simulation
24 引用 (Scopus)

Crystal structure of a biologically functional form of PriB from Escherichia coli reveals a potential single-stranded DNA-binding site

Shioi, S., Ose, T., Maenaka, K., Shiroishi, M., Abe, Y., Kohda, D., Katayama, T. & Ueda, T., 1 28 2005, : : Biochemical and Biophysical Research Communications. 326, 4, p. 766-776 11 p.

研究成果: ジャーナルへの寄稿記事

Single-Stranded DNA
Oligonucleotides
Escherichia coli
Crystal structure
Binding Sites
62 引用 (Scopus)
Egg White
Muramidase
Crystal structure
Complementarity Determining Regions
Light
59 引用 (Scopus)
Chitinases
Muramidase
Tapes
Crystal structure
Substrates
83 引用 (Scopus)

Crystal structure of the anion exchanger domain of human erythrocyte band 3

Arakawa, T., Kobayashi-Yurugi, T., Alguel, Y., Iwanari, H., Hatae, H., Iwata, M., Abe, Y., Hino, T., Ikeda-Suno, C., Kuma, H., Kang, D., Murata, T., Hamakubo, T., Cameron, A. D., Kobayashi, T., Hamasaki, N. & Iwata, S., 11 6 2015, : : Science. 350, 6261, p. 680-684 5 p.

研究成果: ジャーナルへの寄稿記事

Erythrocyte Anion Exchange Protein 1
Anions
Erythrocytes
Congenital Hemolytic Anemia
Chloride-Bicarbonate Antiporters
8 引用 (Scopus)

Crystal structure of the enzyme CapF of Staphyloccus aureus reveals a unique architecture composed of two functional domains

Miyafusa, T., Caaveiro, J. M. M., Tanaka, Y. & Tsumoto, K., 2012, : : Biochemical Journal. 443, p. 671-680 10 p.

研究成果: ジャーナルへの寄稿記事

Polysaccharides
Staphylococcus aureus
Oxidoreductases
Crystal structure
Coenzymes
23 引用 (Scopus)

Crystal structure of the human monocyte-activating receptor, "Group 2" leukocyte Ig-like receptor A5 (LILRA5/LIR9/ILT11)

Shiroishi, M., Kajikawa, M., Kuroki, K., Ose, T., Kohda, D. & Maenaka, K., 7 14 2006, : : Journal of Biological Chemistry. 281, 28, p. 19536-19544 9 p.

研究成果: ジャーナルへの寄稿記事

Monocytes
Leukocytes
Crystal structure
Ligands
Surface Plasmon Resonance
3 引用 (Scopus)

Crystal structures of K33 mutant hen lysozymes with enhanced activities

Goto, T., Ohkuri, T., Shioi, S., Abe, Y., Imoto, T. & Ueda, T., 11 1 2008, : : Journal of biochemistry. 144, 5, p. 619-623 5 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Crystal structure
Micrococcus luteus
Enzyme activity
Mutagenesis
12 引用 (Scopus)

Crystal structures of the ribonuclease MC1 mutants N71T and N71S in complex with 5′-GMP: Structural basis for alterations in substrate specificity

Numata, T., Suzuki, A., Kakuta, Y., Kimura, K., Yao, M., Tanaka, I., Yoshida, Y., Ueda, T. & Kimura, M., 5 13 2003, : : Biochemistry. 42, 18, p. 5270-5278 9 p.

研究成果: ジャーナルへの寄稿記事

Guanosine Monophosphate
ribonuclease T(2)
Guanine
Substrate Specificity
Guanosine
19 引用 (Scopus)

C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia

Behler-Janbeck, F., Takano, T., Maus, R., Stolper, J., Jonigk, D., Tort Tarrés, M., Fuehner, T., Prasse, A., Welte, T., Timmer, M. S. M., Stocker, B. L., Nakanishi, Y., Miyamoto, T., Yamasaki, S. & Maus, U. A., 12 6 2016, : : PLoS pathogens. 12, 12, e1006038.

研究成果: ジャーナルへの寄稿記事

Pneumococcal Pneumonia
C-Type Lectins
Streptococcus pneumoniae
Alveolar Macrophages
Immunity
21 引用 (Scopus)

C-Type Lectin Receptor DCAR Recognizes Mycobacterial Phosphatidyl-Inositol Mannosides to Promote a Th1 Response during Infection

Toyonaga, K., Torigoe, S., Motomura, Y., Kamichi, T., Hayashi, J. M., Morita, Y. S., Noguchi, N., Chuma, Y., Kiyohara, H., Matsuo, K., Tanaka, H., Nakagawa, Y., Sakuma, T., Ohmuraya, M., Yamamoto, T., Umemura, M., Matsuzaki, G., Yoshikai, Y., Yano, I., Miyamoto, T. および1人, Yamasaki, S., 12 20 2016, : : Immunity. 45, 6, p. 1245-1257 13 p.

研究成果: ジャーナルへの寄稿記事

C-Type Lectins
Mycobacterium
Infection
Chemokine CCL2
Monocytes
9 引用 (Scopus)

Curcumin anticipates the suppressed body weight gain with 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice

Ishida, T., Taketoh, J., Nakatsune, E., Kan-o, S., Naito, E., Takeda, S., Mutoh, J., Ishii, Y. & Yamada, H., 10 1 2004, : : Journal of Health Science. 50, 5, p. 474-482 9 p.

研究成果: ジャーナルへの寄稿記事

Curcumin
Weight Gain
Body Weight
Toxicity
Liver
78 引用 (Scopus)

Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication

Lori, C., Ozaki, S., Steiner, S., Böhm, R., Abel, S., Dubey, B. N., Schirmer, T., Hiller, S. & Jenal, U., 7 9 2015, : : Nature. 523, 7559, p. 236-239 4 p.

研究成果: ジャーナルへの寄稿記事

Cell Cycle
Chromosomes
Bacteria
Cyclins
Phosphotransferases
13 引用 (Scopus)

Cycloartane glycosides from three species of Astragalus (Fabaceae)

Linnek, J., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Paululat, T., Avunduk, S., Alankuş-Çalişkan, Ö. & Lacaille-Dubois, M. A., 2 1 2011, : : Helvetica Chimica Acta. 94, 2, p. 230-237 8 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
glucosides
Saponins
Fabaceae
Cicer
3 引用 (Scopus)

Cycloartane-type glycosides from two species of Astragalus (Fabaceae)

Linnek, J., Mitaine-Offer, A. C., Miyamoto, T., Duchamp, O., Mirjolet, J. F. & Lacaille-Dubois, M. A., 12 1 2009, : : Natural product communications. 4, 4, p. 477-478 2 p.

研究成果: ジャーナルへの寄稿記事

Astragalus
Glycosides
Fabaceae
glycosides
Triterpenes

Cycloartane-Type Saponins from Astragalus tmoleus var. tmoleus

Avunduk, S., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., 1 1 2016, : : Natural Product Communications. 11, 1, p. 37-38 2 p.

研究成果: ジャーナルへの寄稿記事

triterpenoid saponins
Astragalus
Saponins
saponins
skeleton
7 引用 (Scopus)

Cysteine-to-serine shuffling using a Saccharomyces cerevisiae expression system improves protein secretion: Case of a nonglycosylated mutant of miraculin, a taste-modifying protein

Ito, K., Sugawara, T., Koizumi, A., Nakajima, K. I., Shimizu-Ibuka, A., Shiroishi, M., Asada, H., Yurugi-Kobayashi, T., Shimamura, T., Asakura, T., Misaka, T., Iwata, S., Kobayashi, T. & Abe, K., 1 1 2011, : : Biotechnology letters. 33, 1, p. 103-107 5 p.

研究成果: ジャーナルへの寄稿記事

Yeast
Serine
Cysteine
Saccharomyces cerevisiae
Proteins
18 引用 (Scopus)
Glucuronosyltransferase
Methylcholanthrene
Microsomes
Cytochrome P-450 Enzyme System
Liver
25 引用 (Scopus)

Cytotoxic acacic acid glycosides from the roots of Albizia coriaria

Noté, O. P., Mitaine-Offer, A. C., Miyamoto, T., Paululat, T., Mirjolet, J. F., Duchamp, O., Pegnyemb, D. E. & Lacaille-Dubois, M. A., 10 23 2009, : : Journal of Natural Products. 72, 10, p. 1725-1730 6 p.

研究成果: ジャーナルへの寄稿記事

Albizzia
Saponins
Glycosides
Inhibitory Concentration 50
Cells
19 引用 (Scopus)

Cytotoxic and ichthyotoxic compounds from marine Opisthobranchia and soft coral

Higuchi, R., Miyamoto, T., Yamada, K. & Komori, T., 1 1 1998, : : Toxicon. 36, 11, p. 1703-1705 3 p.

研究成果: ジャーナルへの寄稿記事

105 引用 (Scopus)

Cytotoxic lavandulyl flavanones from Sophora flavescens

Kang, T. H., Jeong, S. J., Ko, W. G., Kim, N. Y., Lee, B. H., Inagaki, M., Miyamoto, T., Higuchi, R. & Kim, Y. C., 5 1 2000, : : Journal of Natural Products. 63, 5, p. 680-681 2 p.

研究成果: ジャーナルへの寄稿記事

Sophora
Flavanones
Optical rotation
Optical Rotation
Myeloid Leukemia
39 引用 (Scopus)

Cytotoxic spirostane-type saponins from the roots of Chlorophytum borivilianum

Acharya, D., Mitaine-Offer, A. C., Kaushik, N., Miyamoto, T., Paululat, T., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., 1 1 2009, : : Journal of Natural Products. 72, 1, p. 177-181 5 p.

研究成果: ジャーナルへの寄稿記事

Saponins
Cytotoxicity
Colonic Neoplasms
Mass spectrometry
Mass Spectrometry
28 引用 (Scopus)

De- and repolarization mechanism of flagellar morphogenesis during a bacterial cell cycle

Davis, N. J., Cohen, Y., Sanselicio, S., Fumeaux, C., Ozaki, S., Luciano, J., Guerrero-Ferreira, R. C., Wright, E. R., Jenal, U. & Viollier, P. H., 9 1 2013, : : Genes and Development. 27, 18, p. 2049-2062 14 p.

研究成果: ジャーナルへの寄稿記事

Cyclic GMP
Morphogenesis
Cell Cycle
Flagella
Caulobacter crescentus
13 引用 (Scopus)

Decrease in expression of the master operon of flagellin synthesis in a dnaA46 mutant of Escherichia coli

Mizushima, T., Koyanagi, R., Katayama, T., Miki, T. & Sekimizu, K., 1 1 1997, : : Biological and Pharmaceutical Bulletin. 20, 4, p. 327-331 5 p.

研究成果: ジャーナルへの寄稿記事

Cyclic AMP Receptor Protein
Flagellin
Operon
Escherichia coli
Gene Expression
3 引用 (Scopus)

Decrease in prostaglandin level is a prerequisite for the expression of cannabinoid withdrawal: A quasi abstinence approach

Anggadiredja, K., Yamaguchi, T., Tanaka, H., Shoyama, Y., Watanabe, S. & Yamamoto, T., 12 20 2005, : : Brain Research. 1066, 1-2, p. 201-205 5 p.

研究成果: ジャーナルへの寄稿記事

Cannabinoids
Prostaglandins
rimonabant
Dronabinol
Arachidonic Acid
10 引用 (Scopus)

Delta(9)-tetrahydrocannabinol enhances an increase of plasma corticosterone levels induced by forced swim-stress

Sano, K., Koushi, E., Irie, K., Higuchi, S., Tsuchihashi, R., Kinjo, J., Egashira, N., Oishi, R., Uchida, N., Nagai, H., Nishimura, R., Tanaka, H., Morimoto, S., Mishima, K., Iwasaki, K. & Fujiwara, M., 12 1 2009, : : Biological and Pharmaceutical Bulletin. 32, 12, p. 2065-2067 3 p.

研究成果: ジャーナルへの寄稿記事

Dronabinol
Corticosterone
Cannabinoid Receptor Antagonists
Cannabinoid Receptor CB1
Hypothalamus
2 引用 (Scopus)

Demethylation of methylmercury and the enhanced production of formaldehyde in mouse liver

Uchikawa, T., Kanno, T., Maruyama, I., Mori, N., Yasutake, A., Ishii, Y. & Yamada, H., 1 1 2016, : : Journal of Toxicological Sciences. 41, 4, p. 479-487 9 p.

研究成果: ジャーナルへの寄稿記事

Liver
Formaldehyde
Superoxides
Sarcosine
Tissue
5 引用 (Scopus)

Denatured mammalian protein mixtures exhibit unusually high solubility in nucleic acid-free pure water

Futami, J., Fujiyama, H., Kinoshita, R., Nonomura, H., Honjo, T., Tada, H., Matsushita, H., Abe, Y. & Kakimi, K., 11 18 2014, : : PloS one. 9, 11, e113295.

研究成果: ジャーナルへの寄稿記事

Solubility
Nucleic Acids
nucleic acids
solubility
Water
49 引用 (Scopus)

Depression of T-cell epitope generation by stabilizing hen lysozyme

So, T., Ito, H. O., Koga, T., Watanabe, S., Ueda, T. & Imoto, T., 12 19 1997, : : Journal of Biological Chemistry. 272, 51, p. 32136-32140 5 p.

研究成果: ジャーナルへの寄稿記事

T-Lymphocyte Epitopes
Protein Stability
Muramidase
Proteolysis
T-cells
62 引用 (Scopus)

Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease

Li, R., Wang, X. B., Hu, X. J. & Kong, L. Y., 5 1 2013, : : Bioorganic and Medicinal Chemistry Letters. 23, 9, p. 2636-2641 6 p.

研究成果: ジャーナルへの寄稿記事

Cholinesterase Inhibitors
Flavonoids
Catalytic Domain
Alzheimer Disease
Agglomeration
35 引用 (Scopus)
Panax
Monoclonal Antibodies
Membranes
Coloring
Acetic Acid
3 引用 (Scopus)

Detection of a local interaction of hen lysozyme under highly denaturing conditions using chemically 13C-enriched methionine resonance

Abe, Y., Ueda, T., Kawano, K., Tanaka, Y. & Imoto, T., 1 1 1998, : : Journal of Biochemistry. 123, 2, p. 313-317 5 p.

研究成果: ジャーナルへの寄稿記事

Chemical shift
Muramidase
Methionine
Carbon
Digestion
6 引用 (Scopus)

Detection of Ganoderic Acid A in Ganoderma lingzhi by an Indirect Competitive Enzyme-Linked Immunosorbent Assay

Sakamoto, S., Kohno, T., Shimizu, K., Tanaka, H. & Morimoto, S., 5 1 2016, : : Planta medica. 82, 8, p. 747-751 5 p.

研究成果: ジャーナルへの寄稿記事

Ganoderma
Reishi
Immunosorbents
Assays
Enzyme-Linked Immunosorbent Assay
6 引用 (Scopus)

Detection of paeoniflorin and albiflorin by immunostaining technique using anti-paeoniflorin monoclonal antibody

Morinaga, O., Lu, Z., Lin, L., Uto, T., Sangmalee, S., Putalun, W., Tanaka, H. & Shoyama, Y., 1 1 2013, : : Phytochemical Analysis. 24, 2, p. 124-128 5 p.

研究成果: ジャーナルへの寄稿記事

monoclonal antibodies
Monoclonal Antibodies
Paeonia
bovine serum albumin
medicine
9 引用 (Scopus)

Detection of weak ligand interactions of leukocyte Ig-like receptor B1 by fluorescence correlation spectroscopy

Kuroki, K., Kobayashi, S., Shiroishi, M., Kajikawa, M., Okamoto, N., Kohda, D. & Maenaka, K., 3 30 2007, : : Journal of Immunological Methods. 320, 1-2, p. 172-176 5 p.

研究成果: ジャーナルへの寄稿記事

Fluorescence Spectrometry
Leukocytes
Immunoglobulins
Ligands
HLA-G Antigens
9 引用 (Scopus)

Determination of 1,5-anhydro-glucitol-carrier protein conjugates matrix-assisted laser desorption/ionization tof mass spectrometry and antibody formation

Xuan, L. J., Tanaka, H., Morimoto, S., Shoyama, Y., Akanuma, H. & Muraoka, K., 1 1 2000, : : Spectroscopy. 14, 3, p. 85-92 8 p.

研究成果: ジャーナルへの寄稿記事

Sorbitol
Succinic Acid
Ionization
Mass spectrometry
Desorption
16 引用 (Scopus)

Determination of aculeatisides based on immunoassay using a polyclonal antibody against aculeatiside A

Putalun, W., Tanaka, H., Muranaka, T. & Shoyama, Y., 1 1 2002, : : Analyst. 127, 10, p. 1328-1332 5 p.

研究成果: ジャーナルへの寄稿記事

Immunosorbents
immunoassay
Immunoassay
Antibodies
antibody

Determination of hybrids in Papaver species by RAPD, HPLC and ELISA

Shoyama, Y., Tanaka, H., Morimoto, S. & Taura, F., 2000, : : Japanese Journal of Forensic Toxicology. 18, 2, p. 160-161 2 p.

研究成果: ジャーナルへの寄稿記事

Thebaine
Papaver
Enzyme-Linked Immunosorbent Assay
High Pressure Liquid Chromatography
Oligonucleotides
3 引用 (Scopus)

Determination of iriflophenone 3-c-β-d-glucoside from aquilaria spp. by an indirect competitive enzyme-linked immunosorbent assay using a specific polyclonal antibody

Putalun, W., Yusakul, G., Saensom, P., Sritularak, B. & Tanaka, H., 9 1 2013, : : Journal of Food Science. 78, 9, p. C1363-C1367

研究成果: ジャーナルへの寄稿記事

Thymelaeaceae
Aquilaria
Glucosides
polyclonal antibodies
glucosides
17 引用 (Scopus)

Determination of pseudojujubogenin glycosides from Brahmi based on immunoassay using a monoclonal antibody against bacopaside I

Phrompittayarat, W., Putalun, W., Tanaka, H., Jetiyanon, K., Wlttaya-Areekul, S. & Ingkaninan, K., 9 1 2007, : : Phytochemical Analysis. 18, 5, p. 411-418 8 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
immunoassays
Immunoassay
glycosides
monoclonal antibodies
13 引用 (Scopus)

Determination of saposin proteins (sphingolipid activator proteins) in human tissues

Morimoto, S., Yamamoto, Y., O'Brien, J. S. & Kishimoto, Y., 11 1 1990, : : Analytical Biochemistry. 190, 2, p. 154-7 4 p.

研究成果: ジャーナルへの寄稿記事

Sphingolipid Activator Proteins
Saposins
Tissue
Proteins
High Pressure Liquid Chromatography
41 引用 (Scopus)

Determination of tetrahydrocannabinolic acid—carrier protein conjugate by matrix‐assisted laser desorption/ionization mass spectrometry and antibody formation

Goto, Y., Shima, Y., Morimoto, S., Shoyama, Y., Murakami, H., Kusai, A. & Nojima, K., 1 1 1994, : : Organic Mass Spectrometry. 29, 11, p. 668-671 4 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal antibodies
Antigens
Bovine Serum Albumin
antibodies
albumins
13 引用 (Scopus)

Determination of the absolute configuration of sialic acids in gangliosides from the sea cucumber Cucumaria echinata

Kisa, F., Yamada, K., Miyamoto, T., Inagaki, M. & Higuchi, R., 7 1 2007, : : Chemical and Pharmaceutical Bulletin. 55, 7, p. 1051-1052 2 p.

研究成果: ジャーナルへの寄稿記事

Cucumaria
Sea Cucumbers
Sialic Acids
Gangliosides
N-Acetylneuraminic Acid