研究成果 1976 2019

記事
8 引用 (Scopus)

Expression of rat cathepsin D cDNA in Saccharomyces cerevisiae: Implications for intracellular targeting of cathepsin D to vacuoles

Nishimura, Y., Takeshima, H., Sakaguchi, M., Mihara, K., Omura, T., Kato, K. & Himeno, M., 7 1995, : : Journal of biochemistry. 118, 1, p. 168-177 10 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
Vacuoles
Yeast
Saccharomyces cerevisiae
Rats
12 引用 (Scopus)

Extended blood half-life of monomethoxypolyethylene glycol-conjugated hen lysozyme is a key parameter controlling immunological tolerogenicity

So, T., Ito, H. O., Hirata, M., Ueda, T. & Imoto, T., 8 11 1999, : : Cellular and Molecular Life Sciences. 55, 8-9, p. 1187-1194 8 p.

研究成果: ジャーナルへの寄稿記事

Half-Life
Blood
Proteins
T-cells
Antibody Formation
55 引用 (Scopus)

Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis

Kuroki, K., Tsuchiya, N., Shiroishi, M., Rasubala, L., Yamashita, Y., Matsuta, K., Fukazawa, T., Kusaoi, M., Murakami, Y., Takiguchi, M., Juji, T., Hashimoto, H., Kohda, D., Maenaka, K. & Tokunaga, K., 8 15 2005, : : Human Molecular Genetics. 14, 16, p. 2469-2480 12 p.

研究成果: ジャーナルへの寄稿記事

HLA-DRB1 Chains
Epitopes
Rheumatoid Arthritis
Haplotypes
Leukocytes
8 引用 (Scopus)

Factor G utilizes a carbohydrate-binding cleft that is conserved between horseshoe crab and bacteria for the recognition of β-1,3-D-glucans

Ueda, Y., Ohwada, S., Abe, Y., Shibata, T., Iijima, M., Yoshimitsu, Y., Koshiba, T., Nakata, M., Ueda, T. & Kawabata, S. I., 9 15 2009, : : Journal of Immunology. 183, 6, p. 3810-3818 9 p.

研究成果: ジャーナルへの寄稿記事

Horseshoe Crabs
Carbohydrates
Bacteria
Endo-1,4-beta Xylanases
Cellvibrio
3 引用 (Scopus)

Failure analysis of SUS316L flexible hose for hydrogen station and fatigue life prediction method

Murakami, Y., Kanezaki, T., Fukushima, Y., Tanaka, H., Tomuro, J., Kuboyama, K., Matsue, M., Ito, Y. & Ando, H., 1 1 2009, : : Nihon Kikai Gakkai Ronbunshu, A Hen/Transactions of the Japan Society of Mechanical Engineers, Part A. 75, 1, p. 93-102 10 p.

研究成果: ジャーナルへの寄稿記事

Hose
Failure analysis
Hydrogen
Fatigue of materials
Fatigue crack propagation
106 引用 (Scopus)

Fate of DNA replication fork encountering a single DNA lesion during oriC plasmid DNA replication in vitro

Higuchi, K., Katayama, T., Iwai, S., Hidaka, M., Horiuchi, T. & Maki, H., 5 1 2003, : : Genes to Cells. 8, 5, p. 437-449 13 p.

研究成果: ジャーナルへの寄稿記事

DNA Replication
Plasmids
DNA
In Vitro Techniques
Genomic Instability
10 引用 (Scopus)

Fatty acyl-CoA as an endogenous activator of UDP-glucuronosyltransferases

Okamura, K., Ishii, Y., Ikushiro, S. I., Mackenzie, P. I. & Yamada, H., 7 14 2006, : : Biochemical and Biophysical Research Communications. 345, 4, p. 1649-1656 8 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Acyl Coenzyme A
Chemical activation
Cetomacrogol
Hymecromone
3 引用 (Scopus)
Oligomerization
Immunoglobulin G
Light
Oligomers
Dialysis
43 引用 (Scopus)

Fetal pituitary gonadotropin as an initial target of dioxin in its impairment of cholesterol transportation and steroidogenesis in rats

Mutoh, J., Taketoh, J., Okamura, K., Kagawa, T., Ishida, T., Ishii, Y. & Yamada, H., 2 1 2006, : : Endocrinology. 147, 2, p. 927-936 10 p.

研究成果: ジャーナルへの寄稿記事

Pituitary Gonadotropins
Dioxins
Cholesterol
Fetus
Testis
88 引用 (Scopus)

First Direct Evidence for the Mechanism of Δ1-Tetrahydrocannabinolie Acid Biosynthesis

Taura, F., Morimoto, S., Shoyama, Y. & Mechoulam, R., 1 1 1995, : : Journal of the American Chemical Society. 117, 38, p. 9766-9767 2 p.

研究成果: ジャーナルへの寄稿記事

Biosynthesis
Acids
9 引用 (Scopus)

Five new medicagenic acid saponins from Muraltia ononidifolia

Elbandy, M., Miyamoto, T., Delaude, C. & Lacaille-Dubois, M. A., 10 29 2002, : : Helvetica Chimica Acta. 85, 9, p. 2721-2728 8 p.

研究成果: ジャーナルへの寄稿記事

Saponins
Esters
acids
Acids
esters
47 引用 (Scopus)

Flavan-3-ol gallates and proanthocyanidins from Pithecellobium lobatum

Min-Won, L., Morimoto, S., Nonaka, G. I. & Nishioka, I., 1 1 1992, : : Phytochemistry. 31, 6, p. 2117-2120 4 p.

研究成果: ジャーナルへの寄稿記事

Archidendron jiringa
Proanthocyanidins
epigallocatechin
proanthocyanidins
Fabaceae
12 引用 (Scopus)

Flavone-catalyzed apoptosis in Scutellaria baicalensis

Hirunuma, M., Shoyama, Y., Tabata, K., Sakamoto, S., Taura, F., Shoyama, Y., Tanaka, H. & Morimoto, S., 6 1 2011, : : Phytochemistry. 72, 8, p. 752-760 9 p.

研究成果: ジャーナルへの寄稿記事

flavone
Scutellaria baicalensis
flavones
Scutellaria
apoptosis
15 引用 (Scopus)

Flavonoids from Acacia pennata and their cyclooxygenase (COX-1 and COX-2) inhibitory activities

Dongmo, A. B., Miyamoto, T., Yoshikawa, K., Arihara, S. & Lacaille-Dubois, M. A., 9 1 2007, : : Planta Medica. 73, 11, p. 1202-1207 6 p.

研究成果: ジャーナルへの寄稿記事

Acacia
Apigenin
Cyclooxygenase 1
Quercetin
Prostaglandin-Endoperoxide Synthases

Flavonoids from Brazilian propolis

Kusumoto, T., Miyamoto, T., Higuchi, R., Nafady, A. M., Nohara, T., Doi, S. & Sugimoto, H., 2 1 2003, : : Natural Medicines. 57, 1, 1 p.

研究成果: ジャーナルへの寄稿記事

Propolis
Flavonoids
aromadedrin
kaempferol
kaempferide
13 引用 (Scopus)

Flavonoids with free radical scavenging activity and nitric oxide inhibitory effect from the stem bark of Artocarpus gomezianus

Sritularak, B., Tantituvanont, A., Chanvorachote, P., Meksawan, K., Miyamoto, T., Kohno, Y. & Likhitwitayawuid, K., 3 4 2010, : : Journal of Medicinal Plants Research. 4, 5, p. 387-392 6 p.

研究成果: ジャーナルへの寄稿記事

Artocarpus
Flavonoids
Free Radicals
nitric oxide
Nitric Oxide
5 引用 (Scopus)

Fluctuations in free or substrate-complexed lysozyme and a mutant of it detected on x-ray crystallography and comparison with those detected on NMR

Ohmura, T., Motoshima, H., Ueda, T. & Imoto, T., 1 1 2002, : : Journal of Biochemistry. 131, 5, p. 701-704 4 p.

研究成果: ジャーナルへの寄稿記事

Crystallography
Muramidase
Nuclear magnetic resonance
X-Rays
X rays
12 引用 (Scopus)

Fluorescence-based optimization of human bitter taste receptor expression in Saccharomyces cerevisiae

Sugawara, T., Ito, K., Shiroishi, M., Tokuda, N., Asada, H., Yurugi-Kobayashi, T., Shimamura, T., Misaka, T., Nomura, N., Murata, T., Abe, K., Iwata, S. & Kobayashi, T., 5 15 2009, : : Biochemical and Biophysical Research Communications. 382, 4, p. 704-710 7 p.

研究成果: ジャーナルへの寄稿記事

Crystallization
Yeast
Saccharomyces cerevisiae
Fluorescence
Size exclusion chromatography
3 引用 (Scopus)

Foefidissimosides C-F, novel glycosides from the roots of Cucurbita foetidissima

Gaidi, G., Miyamoto, T., Lerche, H. & Lacaille-Dubois, M. A., 7 8 2004, : : Helvetica Chimica Acta. 87, 5, p. 1158-1166 9 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
Cucurbita
glucosides
acids
Acids
5 引用 (Scopus)

Forced retraction of spinal root injury enhances activation of p38 MAPK cascade in infiltrating macrophages

Nomura, H., Furuta, A., Tanaka, Y. & Iwaki, T., 3 1 2005, : : Neuropathology. 25, 1, p. 37-47 11 p.

研究成果: ジャーナルへの寄稿記事

Spinal Injuries
Spinal Nerve Roots
p38 Mitogen-Activated Protein Kinases
Macrophages
Traction
31 引用 (Scopus)

Formation of a monoclonal antibody against glycyrrhizin and development of an ELISA

Tanaka, H. & Shoyama, Y., 1 1 1998, : : Biological and Pharmaceutical Bulletin. 21, 12, p. 1391-1393 3 p.

研究成果: ジャーナルへの寄稿記事

Glycyrrhizic Acid
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
Bovine Serum Albumin
Glycyrrhetinic Acid
95 引用 (Scopus)

Formation of an ATP-DnaA-specific initiation complex requires DnaA arginine 285, a conserved motif in the AAA+ protein family

Kawakamii, H., Keyamura, K. & Katayama, T., 7 22 2005, : : Journal of Biological Chemistry. 280, 29, p. 27420-27430 11 p.

研究成果: ジャーナルへの寄稿記事

Arginine
Adenosine Triphosphate
Proteins
Binding Sites
Adenosine Diphosphate

Formation of ginsenoside-protein conjugates

Park, H., Shoyama, Y., Xuan, L. J. & Tanaka, H., 12 1 1999, : : Studies in Plant Science. 6, C, p. 83-86 4 p.

研究成果: ジャーナルへの寄稿記事

haptens
proteins
antibody formation
bovine serum albumin
solubility
39 引用 (Scopus)

Formation of highly analgesic morphine-6-glucuronide following physiologic concentration of morphine in human brain

Yamada, H., Ishii, K., Ishii, Y., Ieiri, I., Nishio, S., Morioka, T. & Oguri, K., 12 1 2003, : : Journal of Toxicological Sciences. 28, 5, p. 395-401 7 p.

研究成果: ジャーナルへの寄稿記事

Morphine
Analgesics
Brain
Glucuronides
Glucuronosyltransferase
56 引用 (Scopus)

Formation of monoclonal antibody against a major ginseng component, ginsenoside Rb1 and its characterization

Tanaka, H., Fukuda, N. & Shoyama, Y., 1 1 1999, : : Cytotechnology. 29, 2, p. 115-120 6 p.

研究成果: ジャーナルへの寄稿記事

Panax
Monoclonal antibodies
Antigens
Ionization
Mass spectrometry
48 引用 (Scopus)

Formation of monoclonal antibody against a major ginseng component, ginsenoside Rg1 and its characterization: Monoclonal antibody for a ginseng saponin

Fukuda, N., Tanaka, H. & Shoyama, Y., 1 1 2000, : : Cytotechnology. 34, 3, p. 197-204 8 p.

研究成果: ジャーナルへの寄稿記事

Panax
Monoclonal antibodies
Saponins
Antigens
Ionization
1 引用 (Scopus)

Formation of monoclonal antibody against naturally occurring biologically active compounds and their application

Tanaka, H., 6 1 2000, : : Natural Medicines. 54, 3, p. 123-128 6 p.

研究成果: ジャーナルへの寄稿記事

Glycyrrhetinic Acid
Cannabinoids
Glucuronides
Cross Reactions
Colforsin
12 引用 (Scopus)

Formation of α-helix 88-98 is essential in the establishment of higher-order structure from reduced lysozyme

Ueda, T., Nakashima, A., Hashimoto, Y., Miki, T., Yamada, H. & Imoto, T., 1 27 1994, : : Journal of Molecular Biology. 235, 4, p. 1312-1317 6 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Peptide Fragments
Basic Amino Acids
26 引用 (Scopus)

Four new cembrane diterpenes isolated from an Okinawan soft coral Lobophytum crassum with inhibitory effects on nitric oxide production

Wanzola, M., Furuta, T., Kohno, Y., Fukumitsu, S., Yasukochi, S., Watari, K., Tanaka, C., Higuchi, R. & Miyamoto, T., 9 1 2010, : : Chemical and Pharmaceutical Bulletin. 58, 9, p. 1203-1209 7 p.

研究成果: ジャーナルへの寄稿記事

Anthozoa
Diterpenes
Nitric Oxide
Stereochemistry
Macrophages
3 引用 (Scopus)

Functional analysis of CedA based on its structure: Residues important in binding of DNA and RNA polymerase and in the cell division regulation

Abe, Y., Fujisaki, N., Miyoshi, T., Watanabe, N., Katayama, T. & Ueda, T., 5 13 2015, : : Journal of biochemistry. 159, 2, p. 217-223 7 p.

研究成果: ジャーナルへの寄稿記事

Functional analysis
DNA-Directed DNA Polymerase
DNA-Directed RNA Polymerases
Cell Division
Cells
14 引用 (Scopus)

Functional characterization of Val60, a key residue involved in the membrane-oligomerization of fragaceatoxin C, an actinoporin from Actinia fragacea

Morante, K., Caaveiro, J. M. M., Viguera, A. R., Tsumoto, K. & González-Mañas, J. M., 2015, : : FEBS Letters. 589, p. 1840-1846 7 p.

研究成果: ジャーナルへの寄稿記事

Actinium
Oligomerization
Sea Anemones
Membranes
Point Mutation
7 引用 (Scopus)

Functional Contacts between MPER and the Anti-HIV-1 Broadly Neutralizing Antibody 4E10 Extend into the Core of the Membrane

Rujas, E., Insausti, S., García-Porras, M., Sánchez-Eugenia, R., Tsumoto, K., Nieva, J. L. & Caaveiro, J. M. M., 4 21 2017, : : Journal of Molecular Biology. 429, 8, p. 1213-1226 14 p.

研究成果: ジャーナルへの寄稿記事

Neutralizing Antibodies
HIV-1
Membranes
AIDS Vaccines
Epitopes
57 引用 (Scopus)

Functional induction and de-induction of P-glycoprotein by St. John's wort and its ingredients in a human colon adenocarcinoma cell line

Tian, R., Koyabu, N., Morimoto, S., Shoyama, Y., Ohtani, H. & Sawada, Y., 4 1 2005, : : Drug Metabolism and Disposition. 33, 4, p. 547-554 8 p.

研究成果: ジャーナルへの寄稿記事

Hypericum
P-Glycoprotein
Colon
Adenocarcinoma
Cell Line
40 引用 (Scopus)

Functional protein-protein interaction of drug metabolizing enzymes.

Ishii, Y., Takeda, S., Yamada, H. & Oguri, K., 1 1 2005, : : Frontiers in bioscience : a journal and virtual library. 10, p. 887-895 9 p.

研究成果: ジャーナルへの寄稿記事

Drug Interactions
Epoxide Hydrolases
Metabolism
Enzymes
Drug interactions
20 引用 (Scopus)

Furostane-type steroidal saponins from the roots of Chlorophytum borivilianum

Acharya, D., Mitaine-Offer, A. C., Kaushik, N., Miyamoto, T., Paululat, T. & Lacaille-Dubois, M. A., 12 1 2008, : : Helvetica Chimica Acta. 91, 12, p. 2262-2269 8 p.

研究成果: ジャーナルへの寄稿記事

steroids
Saponins
Galactose
Mass spectrometry
mass spectroscopy

Generation of a monoclonal antibody for INI1/hSNF5/BAF47

Harada, A., Hayashi, M., Kuniyoshi, Y., Semba, Y., Sugahara, S., Tachibana, T., Ohkawa, Y. & Fujita, M., 2 1 2014, : : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33, 1, p. 49-51 3 p.

研究成果: ジャーナルへの寄稿記事

Cell Differentiation
Monoclonal Antibodies
Chromatin Assembly and Disassembly
Antibodies
Gene Expression Regulation
18 引用 (Scopus)

Genetic and alkaloid analysis of Papaver species and their F1 hybrid by RAPD, HPLC and ELISA

Shoyama, Y., Kawachi, F., Tanaka, H., Nakai, R., Shibata, T. & Nishi, K., 2 16 1998, : : Forensic Science International. 91, 3, p. 207-217 11 p.

研究成果: ジャーナルへの寄稿記事

Papaver
Alkaloids
Enzyme-Linked Immunosorbent Assay
High Pressure Liquid Chromatography
Thebaine
28 引用 (Scopus)

Genetic variability of the major histocompatibility complex class I homologue encoded by human cytomegalovirus leads to differential binding to the inhibitory receptor ILT2

Valés-Gómez, M., Shiroishi, M., Maenaka, K. & Reyburn, H. T., 2 1 2005, : : Journal of virology. 79, 4, p. 2251-2260 10 p.

研究成果: ジャーナルへの寄稿記事

Human herpesvirus 5
major histocompatibility complex
Major Histocompatibility Complex
Cytomegalovirus
genetic variation
370 引用 (Scopus)

Genetic variants of IL-13 signalling and human asthma and atopy

Heinzmann, A., Mao, X. Q., Akaiwa, M., Kreomer, R. T., Gao, P. S., Ohshima, K., Umeshita, R., Abe, Y., Braun, S., Yamashita, T., Roberts, M. H., Sugimoto, R., Arima, K., Arinobu, Y., Yu, B., Kruse, S., Enomoto, T., Dake, Y., Kawai, M., Shimazu, S. および12人, Sasaki, S., Adra, C. N., Kitaichi, M., Inoue, H., Yamauchi, K., Tomichi, N., Kurimoto, F., Hamasaki, N., Hopkin, J. M., Izuhara, K., Shirakawa, T. & Deichmann, K. A., 3 1 2000, : : Human Molecular Genetics. 9, 4, p. 549-559 11 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-13
Asthma
Immunoglobulin E
Smooth Muscle
Chromosomes
13 引用 (Scopus)
Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., 7 27 2018, : : Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

研究成果: ジャーナルへの寄稿記事

Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome
20 引用 (Scopus)

Glandulosides A-D, triterpene saponins from Acanthophyllum glandulosum

Gaidi, G., Miyamoto, T., Ramezani, M. & Lacaille-Dubois, M. A., 7 1 2004, : : Journal of Natural Products. 67, 7, p. 1114-1118 5 p.

研究成果: ジャーナルへの寄稿記事

Acanthophyllum
Triterpenes
triterpenoid saponins
Saponins
Homo
9 引用 (Scopus)

Glaucasides A-C, three saikosaponins from Atriplex glauca L. var. ifiniensis (Caball) Maire

Jabrane, A., Ben Jannet, H., Miyamoto, T., Tanaka, C., Mirjolet, J. F., Duchamp, O., Harzallah-Skhiri, F. & Lacaille-Dubois, M. A., 1 1 2011, : : Magnetic Resonance in Chemistry. 49, 2, p. 83-89 7 p.

研究成果: ジャーナルへの寄稿記事

Sulfates
Nuclear magnetic resonance spectroscopy
Esters
Cells
glaucaside A
189 引用 (Scopus)

Glucuronidation and the UDP-glucuronosyltransferases in health and disease

Wells, P. G., Mackenzie, P. I., Chowdhury, J. R., Guillemette, C., Gregory, P. A., Ishii, Y., Hansen, A. J., Kessler, F. K., Kim, P. M., Chowdhury, N. R. & Ritter, J. K., 3 1 2004, : : Drug Metabolism and Disposition. 32, 3, p. 281-290 10 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Health
Neoplasm Genes
Xenobiotics
Genetic Therapy
38 引用 (Scopus)

Glucuronide triterpene saponins from Bersama engleriana

Tapondjou, A. L., Miyamoto, T. & Lacaille-Dubois, M. A., 10 1 2006, : : Phytochemistry. 67, 19, p. 2126-2132 7 p.

研究成果: ジャーナルへの寄稿記事

Bersama
oleanolic acid
Triterpenes
triterpenoid saponins
Saponins
11 引用 (Scopus)

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

Kayama, K., Watanabe, S., Takafuji, T., Tsuji, T., Hironaka, K., Matsumoto, M., Nakayama, K. I., Enari, M., Kohno, T., Shiraishi, K., Kiyono, T., Yoshida, K., Sugimoto, N. & Fujita, M., 1 1 2017, : : EMBO Reports. 18, 1, p. 123-137 15 p.

研究成果: ジャーナルへの寄稿記事

Glutamic Acid
Carcinogenesis
Ligases
Ubiquitin
WD40 Repeats
2 引用 (Scopus)

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., 8 1 2018, : : Journal of Cell Science. 131, 15

研究成果: ジャーナルへの寄稿記事

Ribosomal Proteins
Proteasome Endopeptidase Complex
Ubiquitin
Glutamic Acid
Down-Regulation
4 引用 (Scopus)

Guest-Induced Conformational Change of 6-Monosubstituted Cyclodextrin

Fujita, K., Ueda, T., Matsunaga, A. & Imoto, T., 1 1 1983, : : NIPPON KAGAKU KAISHI. 1983, 2, p. 207-213 7 p.

研究成果: ジャーナルへの寄稿記事

Cyclodextrins
Dichroism
Nuclear magnetic resonance
Molecules
43 引用 (Scopus)

Guest-induced conformational change of β-cyclodextrin capped with an environmentally sensitive chromophore

Fujita, K., Ueda, T., Imoto, T., Tabushi, I., Toh, N. & Koga, T., 3 1982, : : Bioorganic Chemistry. 11, 1, p. 72-84 13 p.

研究成果: ジャーナルへの寄稿記事

Cyclodextrins
Chromophores
Circular Dichroism
Nuclear magnetic resonance
3 引用 (Scopus)

Haemolytic actinoporins interact with carbohydrates using their lipid-binding module

Tanaka, K., Martinez Caaveiro, J. M., Morante, K. & Tsumoto, K., 1 1 2017, : : Philosophical Transactions of the Royal Society B: Biological Sciences. 372, 1726, 20160216.

研究成果: ジャーナルへの寄稿記事

toxins
Carbohydrates
carbohydrates
Polysaccharides
Lipids