研究成果 1976 2019

2018
3 引用 (Scopus)

A novel engineered interchain disulfide bond in the constant region enhances the thermostability of adalimumab Fab

Nakamura, H., Oda-Ueda, N., Ueda, T. & Ohkuri, T., 1 1 2018, : : Biochemical and Biophysical Research Communications. 495, 1, p. 7-11 5 p.

研究成果: ジャーナルへの寄稿記事

Disulfides
Pichia
Adalimumab
Computer Simulation
Yeast
1 引用 (Scopus)

A recombinant fab antibody against kwakhurin as a tool for sensitive indirect competitive ELISA

Chanpokapaiboon, K., Khoonrit, P., Yusakul, G., Juengwatanatrakul, T., Putalun, W., Tanaka, H., Sakamoto, S. & Morimoto, S., 1 1 2018, : : Current Pharmaceutical Biotechnology. 19, 14, p. 1170-1176 7 p.

研究成果: ジャーナルへの寄稿記事

Enzyme-Linked Immunosorbent Assay
Antibodies
Monoclonal Antibodies
Pueraria
kwakhurin
7 引用 (Scopus)

Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column

Kiyoshi, M., Caaveiro, J. M. M., Tada, M., Tamura, H., Tanaka, T., Terao, Y., Morante, K., Harazono, A., Hashii, N., Shibata, H., Kuroda, D., Nagatoishi, S., Oe, S., Ide, T., Tsumoto, K. & Ishii-Watabe, A., 12 1 2018, : : Scientific Reports. 8, 1, 3955.

研究成果: ジャーナルへの寄稿記事

Polysaccharides
Antibodies
Column chromatography
Cytotoxicity
Immunoglobulin G
1 引用 (Scopus)

Biophysical analysis of the protein-small molecule interactions to develop small molecule drug discovery

Nagatoishi, S., Martinez Caaveiro, J. M. & Tsumoto, K., 1 1 2018, : : Yakugaku Zasshi. 138, 8, p. 1033-1041 9 p.

研究成果: ジャーナルへの寄稿評論記事

Drug Discovery
Small Molecule Libraries
Thermodynamics
Proteins
Research Personnel
1 引用 (Scopus)

Correction to: Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites (Journal of Natural Medicines, (2018), 72, 1, (32-42), 10.1007/s11418-017-1144-z)

Sakamoto, S., Putalun, W., Vimolmangkang, S., Phoolcharoen, W., Shoyama, Y., Tanaka, H. & Morimoto, S., 1 1 2018, : : Journal of Natural Medicines. 72, 1, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Immunosorbents
Metabolites
Internet
Medicine
Assays

Crystallization of Human Erythrocyte Band 3, the anion exchanger, at the International Space Station “KIBO”

Hatae, H., Inaka, K., Okamura, R., Furubayashi, N., Kamo, M., Kobayashi, T., Abe, Y., Iwata, S. & Hamasaki, N., 10 15 2018, : : Analytical Biochemistry. 559, p. 91-93 3 p.

研究成果: ジャーナルへの寄稿記事

Chloride-Bicarbonate Antiporters
Space stations
Crystallization
Blood
Erythrocytes

Development of a colloidal gold nanoparticle-based immunochromatographic strip for the one-step detection of miroestrol and puerarin

Krittanai, S., Kitisripanya, T., Udomsin, O., Tanaka, H., Sakamoto, S., Juengwatanatrakul, T. & Putalun, W., 11 1 2018, : : Biomedical Chromatography. 32, 11, e4330.

研究成果: ジャーナルへの寄稿記事

Gold Colloid
Nanoparticles
Pueraria
Rejuvenation
Immunosorbents

Development of a Competitive Time-Resolved Fluoroimmunoassay for Paclitaxel

Cui, Q., Tanaka, H., Shoyama, Y., Ye, H. T., Li, F., Tian, E. W., Wu, Y. S. & Chao, Z., 5 1 2018, : : Phytochemical Analysis. 29, 3, p. 284-289 6 p.

研究成果: ジャーナルへの寄稿記事

Fluoroimmunoassay
paclitaxel
Taxus
taxes
Paclitaxel
3 引用 (Scopus)

Development of an immunochromatographic strip incorporating anti-mitragynine monoclonal antibody conjugated to colloidal gold for kratom alkaloids detection

Limsuwanchote, S., Putalun, W., Tanaka, H., Morimoto, S., Keawpradub, N. & Wungsintaweekul, J., 7 1 2018, : : Drug Testing and Analysis. 10, 7, p. 1168-1175 8 p.

研究成果: ジャーナルへの寄稿記事

Gold Colloid
alkaloid
Alkaloids
antibody
gold

Diacylglycerol kinase β induces filopodium formation via its C1, catalytic and carboxy-terminal domains and interacts with the Rac1-GTPase-activating protein, β2-chimaerin

Maeda, Y., Shibata, K., Akiyama, R., Murakami, Y., Takao, S., Murakami, C., Takahashi, D., Sakai, H. & Sakane, F., 9 26 2018, : : Biochemical and Biophysical Research Communications. 504, 1, p. 54-60 7 p.

研究成果: ジャーナルへの寄稿記事

Diacylglycerol Kinase
GTPase-Activating Proteins
Pseudopodia
Cell membranes
Spine
2 引用 (Scopus)

Different expression systems resulted in varied binding properties of anti-paclitaxel single-chain variable fragment antibody clone 1C2

Yusakul, G., Sakamoto, S., Nuntawong, P., Tanaka, H. & Morimoto, S., 1 1 2018, : : Journal of Natural Medicines. 72, 1, p. 310-316 7 p.

研究成果: ジャーナルへの寄稿記事

Single-Chain Antibodies
Paclitaxel
Bombyx
Clone Cells
Escherichia coli
2 引用 (Scopus)

Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1

Tashiro, S., Caaveiro, J. M. M., Nakakido, M., Tanabe, A., Nagatoishi, S., Tamura, Y., Matsuda, N., Liu, D., Hoang, Q. Q. & Tsumoto, K., 9 21 2018, : : ACS Chemical Biology. 13, 9, p. 2783-2793 11 p.

研究成果: ジャーナルへの寄稿記事

X Ray Crystallography
Oxidation-Reduction
Disease Progression
X ray crystallography
Assays
21 引用 (Scopus)

Enzyme-linked immunosorbent assay for the quantitative/qualitative analysis of plant secondary metabolites

Sakamoto, S., Putalun, W., Vimolmangkang, S., Phoolcharoen, W., Shoyama, Y., Tanaka, H. & Morimoto, S., 1 1 2018, : : Journal of Natural Medicines. 72, 1, p. 32-42 11 p.

研究成果: ジャーナルへの寄稿評論記事

Immunosorbents
Metabolites
Immunoassay
Assays
Enzyme-Linked Immunosorbent Assay
1 引用 (Scopus)

Enzyme linked immunosorbent assay for total potent estrogenic miroestrol and deoxymiroestrol of Pueraria candollei, a Thai herb for menopause remedy

Yusakul, G., Kitisripanya, T., Juengwatanatrakul, T., Sakamoto, S., Tanaka, H. & Putalun, W., 6 1 2018, : : Journal of Natural Medicines. 72, 3, p. 641-650 10 p.

研究成果: ジャーナルへの寄稿記事

Pueraria
Immunosorbents
Menopause
Assays
Enzyme-Linked Immunosorbent Assay
3 引用 (Scopus)
diacylglycerol kinase
Diacylglycerol Kinase
Baculoviridae
Purification
Insects
11 引用 (Scopus)
Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., 7 27 2018, : : Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

研究成果: ジャーナルへの寄稿記事

Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome

Green Pharma: A new strategy for drug discovery in academia by targeting glial cells and ATP receptors

Yamashita, T., Makoto, T., Saitoh, H. & Inoue, K., 1 1 2018, : : Yakugaku Zasshi. 138, 8, p. 1027-1031 5 p.

研究成果: ジャーナルへの寄稿評論記事

Purinergic P2 Receptors
Drug Discovery
Neuroglia
Hyperalgesia
Neuralgia
2 引用 (Scopus)

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., 8 1 2018, : : Journal of Cell Science. 131, 15

研究成果: ジャーナルへの寄稿記事

Ribosomal Proteins
Proteasome Endopeptidase Complex
Ubiquitin
Glutamic Acid
Down-Regulation
2 引用 (Scopus)
Antigens
Paclitaxel
Antibodies
Immunoglobulin G
Light
Amyloid
Light
Amyloidosis
epigallocatechin gallate
Oxidation

Inhibition of amyloid fibril formation in the variable domain of λ6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate

Abe, Y., Odawara, N., Aeimhirunkailas, N., Shibata, H., Fujisaki, N., Tachibana, H. & Ueda, T., 12 1 2018, : : Biochimica et Biophysica Acta - General Subjects. 1862, 12, p. 2570-2578 9 p.

研究成果: ジャーナルへの寄稿記事

Amyloid
Light
Amyloidosis
epigallocatechin gallate
Oxidation
1 引用 (Scopus)

Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody

Miyanabe, K., Akiba, H., Kuroda, D., Nakakido, M., Kusano-Arai, O., Iwanari, H., Hamakubo, T., Caaveiro, J. M. M. & Tsumoto, K., 7 1 2018, : : Journal of biochemistry. 164, 1, p. 65-76 12 p.

研究成果: ジャーナルへの寄稿記事

Biological Phenomena
Molecular recognition
Peptides
Antibodies
Free energy
3 引用 (Scopus)

Introduction of a glycosylation site in the constant region decreases the aggregation of adalimumab Fab

Nakamura, H., Oda-Ueda, N., Ueda, T. & Ohkuri, T., 9 5 2018, : : Biochemical and Biophysical Research Communications. 503, 2, p. 752-756 5 p.

研究成果: ジャーナルへの寄稿記事

Glycosylation
Agglomeration
Density (optical)
Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase
Pichia
7 引用 (Scopus)

Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection

Imai, T., Matsumura, T., Mayer-Lambertz, S., Wells, C. A., Ishikawa, E., Butcher, S. K., Barnett, T. C., Walker, M. J., Imamura, A., Ishida, H., Ikebe, T., Miyamoto, T., Ato, M., Ohga, S., Lepenies, B., Van Sorge, N. M. & Yamasaki, S., 11 6 2018, : : Proceedings of the National Academy of Sciences of the United States of America. 115, 45, p. E10662-E10671

研究成果: ジャーナルへの寄稿記事

C-Type Lectins
Streptococcus
Immunity
Macrophages
Infection
8 引用 (Scopus)

Lycodine-type alkaloids and their glycosides from Lycopodiastrum casuarinoides

Wang, L. L., Hao, L. J., Zhou, Z. B., Zhu, X. L., Shi, Z. H., Miyamoto, T. & Pan, K., 10 1 2018, : : Phytochemistry. 154, p. 63-72 10 p.

研究成果: ジャーナルへの寄稿記事

Lycopodium alkaloids
Lycopodium
Glycosides
Alkaloids
glycosides

Molecular basis for governing the morphology of type-I collagen fibrils by Osteomodulin

Tashima, T., Nagatoishi, S., Martinez Caaveiro, J. M., Nakakido, M., Sagara, H., Kusano-Arai, O., Iwanari, H., Mimuro, H., Hamakubo, T., Ohnuma, S. I. & Tsumoto, K., 12 1 2018, : : Communications Biology. 1, 1, 33.

研究成果: ジャーナルへの寄稿記事

公開
Collagen Type I
collagen
Collagen
Proteoglycans
Static Electricity
1 引用 (Scopus)

Oleanane-type glycosides from the roots of Weigela florida “rumba” and evaluation of their antibody recognition

Champy-Tixier, A. S., Mitaine-Offer, A. C., Real Fernández, F., Miyamoto, T., Tanaka, C., Papini, A. M. & Lacaille-Dubois, M. A., 7 1 2018, : : Fitoterapia. 128, p. 198-203 6 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
Acids
Antibodies
Triterpenes
Multiple Sclerosis
2 引用 (Scopus)

Phytochemistry of weigela x “kosteriana variegata” (Caprifoliaceae)

Andriamisaina, N., Mitaine-Offer, A. C., Pruvot, B., Chluba, J., Miyamoto, T., Tanaka, C. & Lacaille-Dubois, M. A., 1 1 2018, : : Natural product communications. 13, 4, p. 403-406 4 p.

研究成果: ジャーナルへの寄稿記事

Caprifoliaceae
Weigela
plant biochemistry
Glycosides
glycosides
5 引用 (Scopus)

Sensitive detection of fluorescence in western blotting by merging images

Kondo, Y., Higa, S., Iwasaki, T., Matsumoto, T., Maehara, K., Harada, A., Baba, Y., Fujita, M. & Ohkawa, Y., 1 2018, : : PloS one. 13, 1, e0191532.

研究成果: ジャーナルへの寄稿記事

Merging
Western blotting
Fluorescence
Western Blotting
fluorescence
2 引用 (Scopus)
Glycosides
Immunosorbents
Monoclonal antibodies
Assays
Enzymes
3 引用 (Scopus)
Leukemia
Derivatives
Cephalotaxus
Immunosorbents
Acute Promyelocytic Leukemia
2 引用 (Scopus)

Structure–function analyses of a stereotypic rheumatoid factor unravel the structural basis for germline-encoded antibody autoreactivity

Shiroishi, M., Ito, Y., Shimokawa, K., Lee, M., Kusakabe, T. & Ueda, T., 1 1 2018, : : Journal of Biological Chemistry. 293, 18, p. 7008-7016 9 p.

研究成果: ジャーナルへの寄稿記事

Rheumatoid Factor
Antibodies
Complementarity Determining Regions
Hematologic Diseases
Immunoglobulin G
3 引用 (Scopus)

Terpenoid glycosides from the root's barks of Eriocoelum microspermum Radlk. ex Engl.

Pertuit, D., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Delaude, C. & Lacaille-Dubois, M. A., 8 1 2018, : : Phytochemistry. 152, p. 182-190 9 p.

研究成果: ジャーナルへの寄稿記事

Terpenes
Glycosides
terpenoids
glycosides
bark

The aryl hydrocarbon receptor is indispensable for dioxin-induced defects in sexually-dimorphic behaviors due to the reduction in fetal steroidogenesis of the pituitary-gonadal axis in rats

Hattori, Y., Takeda, T., Nakamura, A., Nishida, K., Shioji, Y., Fukumitsu, H., Yamada, H. & Ishii, Y., 8 1 2018, : : Biochemical Pharmacology. 154, p. 213-221 9 p.

研究成果: ジャーナルへの寄稿記事

Multifetal Pregnancy Reduction
Aryl Hydrocarbon Receptors
Dioxins
Rats
Defects
1 引用 (Scopus)

The DnaA AAA+ Domain His136 residue directs DnaB replicative helicase to the unwound region of the replication origin, oriC

Sakiyama, Y., Nishimura, M., Hayashi, C., Akama, Y., Ozaki, S. & Katayama, T., 8 31 2018, : : Frontiers in Microbiology. 9, AUG, 2017.

研究成果: ジャーナルへの寄稿記事

DnaB Helicases
Replication Origin
Nucleoproteins
Single-Stranded DNA
Protein Subunits

Triterpene saponins of the root bark of Olax obtusifolia De Wild

Pertuit, D., Mitaine-Offer, A. C., Miyamoto, T., Tanaka, C., Delaude, C. & Lacaille-Dubois, M. A., 12 1 2018, : : Phytochemistry Letters. 28, p. 174-178 5 p.

研究成果: ジャーナルへの寄稿記事

Triterpenes
triterpenoid saponins
Saponins
bark
Acids
2 引用 (Scopus)

Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody

Miyanabe, K., Yamashita, T., Abe, Y., Akiba, H., Takamatsu, Y., Nakakido, M., Hamakubo, T., Ueda, T., Martinez Caaveiro, J. M. & Tsumoto, K., 7 17 2018, : : Biochemistry. 57, 28, p. 4177-4185 9 p.

研究成果: ジャーナルへの寄稿記事

Antibody Affinity
Tyrosine
Peptides
Antibodies
Proteins
13 引用 (Scopus)
Diacylglycerol Kinase
Phosphatidic Acids
Diglycerides
Phosphatidylinositols
Isoenzymes

黄色ブドウ球菌の鉄取り込み機構:ISD

Martinez Caaveiro, J. M. & Tsumoto, K., 1 1 2018, : : Seikagaku. 90, 3, p. 279-289 11 p.

研究成果: ジャーナルへの寄稿記事

Heme
Staphylococcus aureus
Iron
2017
1 引用 (Scopus)

A dihydrochalcone derivative and further steroidal saponins from Sansevieria trifasciata Prain

Tchegnitegni, B. T., Teponno, R. B., Jenett-Siems, K., Melzig, M. F., Miyamoto, T. & Tapondjou, L. A., 10 26 2017, : : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 72, 11-12, p. 477-482 6 p.

研究成果: ジャーナルへの寄稿記事

Sansevieria
Aconitic Acid
Saponins
Derivatives
Spectroscopic analysis
3 引用 (Scopus)

A lateral flow colloidal gold-based immunoassay for rapid detection of miroestrol in samples of White Kwao Krua, a phytoestrogen-rich plant

Kitisripanya, T., Inyai, C., Komaikul, J., Krittanai, S., Juengwatanatrakul, T., Sakamoto, S., Tanaka, H., Morimoto, S. & Putalun, W., 10 1 2017, : : Journal of Natural Medicines. 71, 4, p. 659-664 6 p.

研究成果: ジャーナルへの寄稿記事

Gold Colloid
Phytoestrogens
Immunoassay
Assays
Immunosorbents
1 引用 (Scopus)

A monoclonal antibody-based immunoassay for the determination of oxyresveratrol from Artocarpus lacucha Buch.-Ham

Kitisripanya, T., Inyai, C., Krittanai, S., Likhitwitayawuid, K., Sritularak, B., Ploypradith, P., Tanaka, H., Morimoto, S. & Putalun, W., 7 1 2017, : : Journal of Natural Medicines. 71, 3, p. 523-530 8 p.

研究成果: ジャーナルへの寄稿記事

Artocarpus
Immunoassay
Monoclonal Antibodies
Assays
Immunosorbents
3 引用 (Scopus)

A new highly selective and specific anti-puerarin polyclonal antibody for determination of puerarin using a mannich reaction hapten conjugate

Udomsin, O., Krittanai, S., Kitisripanya, T., Tanaka, H. & Putalun, W., 10 1 2017, : : Pharmacognosy Magazine. 13, 52, p. S845-S851

研究成果: ジャーナルへの寄稿記事

Haptens
Enzyme-Linked Immunosorbent Assay
Pueraria
Antibodies
Bovine Serum Albumin
1 引用 (Scopus)

An immunochromatographic assay for rapid etection of salvinorin A

Paudel, M. K., Shirota, O., Sakamoto, S., Morimoto, S. & Tanaka, H., 7 4 2017, : : Journal of Immunoassay and Immunochemistry. 38, 4, p. 438-448 11 p.

研究成果: ジャーナルへの寄稿記事

salvinorin A
Immunochromatography
Assays
Salvia
Lamiaceae
2 引用 (Scopus)
Kampo Medicine
Scutellaria baicalensis
Immunosorbents
Glucuronides
Assays
5 引用 (Scopus)

Antibody fragments for on-site testing of cannabinoids generated via in vitro affinity maturation

Morita, I., Oyama, H., Yasuo, M., Matsuda, K., Katagi, K., Ito, A., Tatsuda, H., Tanaka, H., Morimoto, S. & Kobayashi, N., 1 1 2017, : : Biological and Pharmaceutical Bulletin. 40, 2, p. 174-181 8 p.

研究成果: ジャーナルへの寄稿記事

Immunoglobulin Fragments
Dronabinol
Cannabinoids
Immunoglobulin Variable Region
Single-Chain Antibodies
2 引用 (Scopus)

Anti-mitragynine monoclonal antibody-based ELISA for determination of alkaloids in the kratom cocktail

Limsuwanchote, S., Putalun, W., Keawpradub, N., Tanaka, H., Morimoto, S. & Wungsintaweekul, J., 1 1 2017, : : Forensic Toxicology. 35, 1, p. 167-172 6 p.

研究成果: ジャーナルへの寄稿記事

Alkaloids
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
Immunosorbents
Assays
1 引用 (Scopus)

Bacterial expression of a single-chain variable fragment (scFv) antibody against ganoderic acid a: A cost-effective approach for quantitative analysis using the scfv-based enzyme-linked immunosorbent assay

Yusakul, G., Nuntawong, P., Sakamoto, S., Bhuket, P. R. N., Kohno, T., Kikkawa, N., Rojsitthisak, P., Shimizu, K., Tanaka, H. & Morimoto, S., 1 1 2017, : : Biological and Pharmaceutical Bulletin. 40, 10, p. 1767-1774 8 p.

研究成果: ジャーナルへの寄稿記事

Single-Chain Antibodies
Enzyme-Linked Immunosorbent Assay
Costs and Cost Analysis
Immunoassay
Ganoderma
12 引用 (Scopus)

Berberine Induces Apoptotic Cell Death via Activation of Caspase-3 and -8 in HL-60 Human Leukemia Cells: Nuclear Localization and Structure-Activity Relationships

Okubo, S., Uto, T., Goto, A., Tanaka, H., Nishioku, T., Yamada, K. & Shoyama, Y., 1 1 2017, : : American Journal of Chinese Medicine. 45, 7, p. 1497-1511 15 p.

研究成果: ジャーナルへの寄稿記事

Berberine
Caspase 8
Structure-Activity Relationship
Caspase 3
Leukemia