研究成果 1976 2019

2008
43 引用 (Scopus)

An in vitro multistep carcinogenesis model for human cervical cancer

Narisawa-Saito, M., Yoshimatsu, Y., Ohno, S. I., Yugawa, T., Egawa, N., Fujita, M., Hirohashi, S. & Kiyono, T., 7 15 2008, : : Cancer Research. 68, 14, p. 5699-5705 7 p.

研究成果: ジャーナルへの寄稿記事

Uterine Cervical Neoplasms
Carcinogenesis
Oncogenes
Neoplasms
Neoplastic Stem Cells
9 引用 (Scopus)

Artemisinin production by shoot regeneration of Artemisia annua L. using thidiazuron

Lualon, W., De-Eknamkul, W., Tanaka, H., Shoyama, Y. & Putalun, W., 1 1 2008, : : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 63, 1-2, p. 96-100 5 p.

研究成果: ジャーナルへの寄稿記事

Artemisia annua
Plant Growth Regulators
Regeneration
Plant Stems
Hormones
36 引用 (Scopus)

A simple and versatile self-assembled monolayer based surface plasmon resonance immunosensor for highly sensitive detection of 2,4-D from natural water resources

Kim, S. J., Gobi, K. V., Tanaka, H., Shoyama, Y. & Miura, N., 3 14 2008, : : Sensors and Actuators, B: Chemical. 130, 1, p. 281-289 9 p.

研究成果: ジャーナルへの寄稿記事

Immunosensors
water resources
2,4-Dichlorophenoxyacetic Acid
Surface plasmon resonance
Self assembled monolayers
5 引用 (Scopus)

Cannabinoids act as necrosis-inducing factors in Cannabis sativa

Shoyama, Y., Sugawa, C., Tanaka, H. & Morimoto, S., 12 2008, : : Plant Signaling and Behavior. 3, 12, p. 1111-1112 2 p.

研究成果: ジャーナルへの寄稿記事

cannabinoids
Cannabis sativa
necrosis
permeability
Cannabis
8 引用 (Scopus)

Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa

Taguchi, C., Taura, F., Tamada, T., Shoyama, Y., Shoyama, Y., Tanaka, H., Kuroki, R. & Morimoto, S., 3 13 2008, : : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 64, 3, p. 217-220 4 p.

研究成果: ジャーナルへの寄稿記事

Polyketide Synthases
Cannabis
Crystallization
X-Ray Diffraction
HEPES
3 引用 (Scopus)

Crystal structures of K33 mutant hen lysozymes with enhanced activities

Goto, T., Ohkuri, T., Shioi, S., Abe, Y., Imoto, T. & Ueda, T., 11 1 2008, : : Journal of biochemistry. 144, 5, p. 619-623 5 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Crystal structure
Micrococcus luteus
Enzyme activity
Mutagenesis
40 引用 (Scopus)

Development of an enzyme-linked immunosorbent assay (ELISA) using highly-specific monoclonal antibodies against plumbagin

Sakamoto, S., Putalun, W., Tsuchihashi, R., Morimoto, S., Kinjo, J. & Tanaka, H., 1 21 2008, : : Analytica Chimica Acta. 607, 1, p. 100-105 6 p.

研究成果: ジャーナルへの寄稿記事

Immunosorbents
antibody
Assays
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
4 引用 (Scopus)

Development of an enzyme linked immunosorbent assay for direct determination of anticancer drug vitamin K3 in serum

Sakamoto, S., Sakoda, J., Morinaga, O., Waraporn, P., Tsuchihashi, R., Morimoto, S., Kinjo, J. & Tanaka, H., 8 2008, : : Journal of Health Science. 54, 4, p. 508-511 4 p.

研究成果: ジャーナルへの寄稿記事

Vitamin K 3
Immunosorbents
Assays
Enzyme-Linked Immunosorbent Assay
Enzymes
32 引用 (Scopus)

Drug-induced phospholipidosis is caused by blockade of mannose 6-phosphate receptor-mediated targeting of lysosomal enzymes

Ikeda, K., Hirayama, M., Hirota, Y., Asa, E., Seki, J. & Tanaka, Y., 12 5 2008, : : Biochemical and Biophysical Research Communications. 377, 1, p. 268-274 7 p.

研究成果: ジャーナルへの寄稿記事

IGF Type 2 Receptor
Enzymes
Pharmaceutical Preparations
Phospholipids
Endosomes
30 引用 (Scopus)
Phosphorylation
Endocytosis
Epidermal Growth Factor Receptor
Endosomes
Non-Small Cell Lung Carcinoma
20 引用 (Scopus)

Furostane-type steroidal saponins from the roots of Chlorophytum borivilianum

Acharya, D., Mitaine-Offer, A. C., Kaushik, N., Miyamoto, T., Paululat, T. & Lacaille-Dubois, M. A., 12 1 2008, : : Helvetica Chimica Acta. 91, 12, p. 2262-2269 8 p.

研究成果: ジャーナルへの寄稿記事

steroids
Saponins
Galactose
Mass spectrometry
mass spectroscopy
32 引用 (Scopus)

Hda monomerization by ADP binding promotes replicase clamp-mediated DnaA-ATP hydrolysis

Su'etsugu, M., Nakamura, K., Keyamura, K., Kudo, Y. & Katayama, T., 12 26 2008, : : Journal of Biological Chemistry. 283, 52, p. 36118-36131 14 p.

研究成果: ジャーナルへの寄稿記事

Clamping devices
Adenosine Diphosphate
Hydrolysis
Adenosine Triphosphate
Initiator Codon
1 引用 (Scopus)

Heterogeneous packing in the folding/unfolding intermediate state of bitter gourd trypsin inhibitor

Takahashi, D., Matsumoto, S., Nishimoto, E., Otosu, T. & Yamashita, S., 7 1 2008, : : Bioscience, Biotechnology and Biochemistry. 72, 6, p. 1498-1505 8 p.

研究成果: ジャーナルへの寄稿記事

Momordica charantia
Trypsin Inhibitors
Conformations
Fluorescence
Protein Unfolding
9 引用 (Scopus)

Improvement of pseudojujubogenin glycosides production from regenerated Bacopa monnieri (L.) Wettst. and enhanced yield by elicitors

Kamonwannasit, S., Phrompittayarat, W., Ingkaninan, K., Tanaka, H. & Putalun, W., 12 1 2008, : : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 63, 11-12, p. 879-883 5 p.

研究成果: ジャーナルへの寄稿記事

Bacopa
Glycosides
Plant Growth Regulators
Chitosan
Yeast
19 引用 (Scopus)

Isolation and structure of a monomethylated ganglioside possessing neuritogenic activity from the ovary of the sea urchin Diadema setosum

Yamada, K., Tanabe, K., Miyamoto, T., Kusumoto, T., Inagaki, M. & Higuchi, R., 5 19 2008, : : Chemical and Pharmaceutical Bulletin. 56, 5, p. 734-738 5 p.

研究成果: ジャーナルへの寄稿記事

Sea Urchins
Gangliosides
Ovary
phytosphingosine
Ceramides
44 引用 (Scopus)

Modes of overinitiation, dnaA gene expression, and inhibition of cell division in a novel cold-sensitive hda mutant of Escherichia coli

Fujimitsu, K., Su'etsugu, M., Yamaguchi, Y., Mazda, K., Fu, N., Kawakami, H. & Katayama, T., 8 1 2008, : : Journal of bacteriology. 190, 15, p. 5368-5381 14 p.

研究成果: ジャーナルへの寄稿記事

Cell Division
Escherichia coli
Gene Expression
Adenosine Triphosphate
Genes
15 引用 (Scopus)

Neuritogenic activity-guided isolation of a free base form manzamine A from a marine sponge, Acanthostrongylophora aff. ingens (Thiele, 1899)

Zhang, B., Higuchi, R., Miyamoto, T. & Van Soest, R. W. M., 6 1 2008, : : Chemical and Pharmaceutical Bulletin. 56, 6, p. 866-869 4 p.

研究成果: ジャーナルへの寄稿記事

Porifera
Alkaloids
Military Personnel
Salts
Nuclear magnetic resonance
3 引用 (Scopus)

Pharmacologically active saikosaponin in Bupleurum falcatum detected by competitive ELISA and eastern blotting using monoclonal antibodies

Tae, K. S., Zhu, S. H., Sang, C. L., Shoyama, Y. & Tanaka, H., 5 5 2008, : : Plant Production Science. 11, 2, p. 192-197 6 p.

研究成果: ジャーナルへの寄稿記事

Bupleurum falcatum
monoclonal antibodies
enzyme-linked immunosorbent assay
cork
immunoassays
5 引用 (Scopus)

Piperine, a pepper ingredient, improves the hepatic increase in free fatty acids caused by 2,3,7,8-tetrachlorodibenzo-p-dioxin

Ishida, T., Ishizaki, M., Tsutsumi, S., Ishii, Y. & Yamada, H., 10 1 2008, : : Journal of Health Science. 54, 5, p. 551-558 8 p.

研究成果: ジャーナルへの寄稿記事

piperine
Nonesterified Fatty Acids
Liver
Dioxins
Piper nigrum
16 引用 (Scopus)

Production, characterization of a monoclonal antibody against aristolochic acid-II and development of its assay system

Tian, M., Tanaka, H., Shang, M. Y., Karashima, S., Chao, Z., Wang, X., Cai, S. Q. & Shoyama, Y., 5 27 2008, : : American Journal of Chinese Medicine. 36, 2, p. 425-436 12 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Hybridomas
Enzyme-Linked Immunosorbent Assay
Aminopterin
Glycyrrhizic Acid
15 引用 (Scopus)

Production of glycyrrhizin in callus cultures of licorice

Wongwicha, W., Tanaka, H., Shoyama, Y., Tuvshintogtokh, I. & Putalun, W., 1 1 2008, : : Zeitschrift fur Naturforschung - Section C Journal of Biosciences. 63, 5-6, p. 413-417 5 p.

研究成果: ジャーナルへの寄稿記事

Naphthaleneacetic Acids
Glycyrrhizic Acid
Glycyrrhiza
Bony Callus
N-benzyladenine

Proteasome affects the expression of aryl hydrocarbon receptor-regulated proteins

Ishida, T., Kawakami, M., Baba, H., Yahata, M., Mutoh, J., Takeda, S., Fujita, H., Tanaka, Y., Ishii, Y. & Yamada, H., 11 1 2008, : : Environmental Toxicology and Pharmacology. 26, 3, p. 348-354 7 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Receptors
Proteasome Endopeptidase Complex
Cytochrome P-450 CYP1A1
Methylcholanthrene
Proteins
13 引用 (Scopus)

Protein-protein interaction on lysozyme crystallization revealed by rotational diffusion analysis

Takahashi, D., Nishimoto, E., Murase, T. & Yamashita, S., 6 1 2008, : : Biophysical Journal. 94, 11, p. 4484-4492 9 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Crystallization
Proteins
Biological Phenomena
Fluorescence Polarization
21 引用 (Scopus)

Quick analysis of baicalin in Scutellariae Radix by enzyme-linked immunosorbent assay using a monoclonal antibody

Kido, K., Morinaga, O., Shoyama, Y. & Tanaka, H., 10 19 2008, : : Talanta. 77, 1, p. 346-350 5 p.

研究成果: ジャーナルへの寄稿記事

Scutellaria baicalensis
Immunosorbents
Assays
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
85 引用 (Scopus)

Role of macrophages in inflammatory lymphangiogenesis: Enhanced production of vascular endothelial growth factor C and D through NF-κB activation

Watari, K., nakao, S., Fotovati, A., Basaki, Y., Hosoi, F., Bereczky, B., Higuchi, R., Miyamoto, T., Kuwano, M. & Ono, M., 12 19 2008, : : Biochemical and Biophysical Research Communications. 377, 3, p. 826-831 6 p.

研究成果: ジャーナルへの寄稿記事

Vascular Endothelial Growth Factor D
Lymphangiogenesis
Vascular Endothelial Growth Factor C
Macrophages
Interleukin-1
12 引用 (Scopus)

Roles for the AAA+ motifs of DnaA in the initiation of DNA replication

Katayama, T., 2 2008, : : Biochemical Society Transactions. 36, 1, p. 78-82 5 p.

研究成果: ジャーナルへの寄稿記事

Replication Origin
DNA Replication
DNA
Adenosine Triphosphate
Molecules
11 引用 (Scopus)

Stability studies of saponins in Bacopa monnieri dried ethanolic extracts

Phrompittayarat, W., Wittaya-areekul, S., Jetiyanon, K., Putalun, W., Tanaka, H. & Ingkaninan, K., 11 1 2008, : : Planta medica. 74, 14, p. 1756-1763 8 p.

研究成果: ジャーナルへの寄稿記事

Bacopa
Saponins
Complex Mixtures
Moisture
Lead compounds
21 引用 (Scopus)

Steroidal saponins from the roots of Smilax aspera subsp. mauritanica

Belhouchet, Z., Sautour, M., Miyamoto, T. & Lacaille-Dubois, M. A., 9 1 2008, : : Chemical and Pharmaceutical Bulletin. 56, 9, p. 1324-1327 4 p.

研究成果: ジャーナルへの寄稿記事

Smilax
Liliaceae
Candida
Saponins
Microbial Sensitivity Tests

Structural Analysis of Excitatory Nerupeptides TEP-1 and TEP-2 Isolated from the Prosobranch Gastopod Thais clavigera

Nose, T., Horiuchi, Y., Abe, Y., Shimohigashi, Y. & Morishita, F., 3 2008, Peptide Science 2007. p. 273-276 4 p.

研究成果: 著書/レポートタイプへの貢献章 (査読済み)

80 引用 (Scopus)

Testing geometrical discrimination within an enzyme active site: Constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole

Sigala, P. A., Kraut, D., Caaveiro, J. M. M., Pybus, B., Ruben, E., Ringe, D., Petsko, G. A. & Herschlag, D., 2008, : : Journal of the American Chemical Society. 130, p. 13696-13708 13 p.

研究成果: ジャーナルへの寄稿記事

Ketosteroids
Isomerases
Hydrogen Bonding
Catalytic Domain
Hydrogen bonds
31 引用 (Scopus)

Triterpene glycosides from the roots of Astragalus flavescens

Avunduk, S., Mitaine-Offer, A. C., Alankuş-Çalişkan, Ö., Miyamoto, T., Şenol, S. G. & Lacaille-Dubois, M. A., 1 1 2008, : : Journal of Natural Products. 71, 1, p. 141-145 5 p.

研究成果: ジャーナルへの寄稿記事

Triterpenes
Saponins
Glycosides
Mass spectrometry
Mass Spectrometry
2007
2 引用 (Scopus)
disulfide bonds
Muramidase
lysozyme
Disulfides
Cysteine
4 引用 (Scopus)

Analysis of internal motions of interleukin-13 variant associated with severe bronchial asthma using 15N NMR relaxation measurements

Yoshida, Y., Ohkuri, T., Takeda, C., Kuroki, R., Izuhara, K., Imoto, T. & Ueda, T., 6 22 2007, : : Biochemical and Biophysical Research Communications. 358, 1, p. 292-297 6 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-13
Asthma
Nuclear magnetic resonance
Signal transduction
Mutation
21 引用 (Scopus)

An enzyme-linked immunosorbant assay using polyclonal antibodies against bacopaside I

Phrompittayarat, W., Putalun, W., Tanaka, H., Wittaya-Areekul, S., Jetiyanon, K. & Ingkaninan, K., 2 12 2007, : : Analytica Chimica Acta. 584, 1, p. 1-6 6 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
antibody
Assays
assay
enzyme
21 引用 (Scopus)

A particular hydrophobic cluster in the residual structure of reduced lysozyme drastically affects the amyloid fibrils formation

Mishima, T., Ohkuri, T., Monji, A., Imoto, T. & Ueda, T., 5 11 2007, : : Biochemical and Biophysical Research Communications. 356, 3, p. 769-772 4 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Amyloid
Modulation
Mutation
34 引用 (Scopus)

A role for Rab5 activity in the biogenesis of endosomal and lysosomal compartments

Hirota, Y., Kuronita, T., Fujita, H. & Tanaka, Y., 12 7 2007, : : Biochemical and Biophysical Research Communications. 364, 1, p. 40-47 8 p.

研究成果: ジャーナルへの寄稿記事

Endosomes
Fusion reactions
Phosphatidylinositol 3-Kinase
Lysosomes
Monomeric GTP-Binding Proteins
3 引用 (Scopus)

Assignment of 1H, 13C and 15N resonances of N-terminal domain of DnaA protein

Abe, Y., Watanabe, N., Yoshida, Y., Ebata, F., Katayama, T. & Ueda, T., 7 1 2007, : : Biomolecular NMR Assignments. 1, 1, p. 57-59 3 p.

研究成果: ジャーナルへの寄稿記事

DnaB Helicases
Oligomerization
Escherichia coli
Proteins
Protein Domains
29 引用 (Scopus)

Biologically active gangliosides from echinoderms

Higuchi, R., Inagaki, M., Yamada, K. & Miyamoto, T., 10 1 2007, : : Journal of Natural Medicines. 61, 4, p. 367-370 4 p.

研究成果: ジャーナルへの寄稿評論記事

Gangliosides
Stars
Cucumaria
Holothuria
Stichopus
83 引用 (Scopus)

Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa

Taura, F., Sirikantaramas, S., Shoyama, Y., Yoshikai, K., Shoyama, Y. & Morimoto, S., 6 26 2007, : : FEBS Letters. 581, 16, p. 2929-2934 6 p.

研究成果: ジャーナルへの寄稿記事

Cannabis
Cannabinoids
Fibers
Enzymes
Acids
8 引用 (Scopus)

Characterization and diagnostic use of a recombinant single-chain antibody specific for the gp116 envelop glycoprotein of Yellow head virus

Intorasoot, S., Tanaka, H., Shoyama, Y. & Leelamanit, W., 8 1 2007, : : Journal of Virological Methods. 143, 2, p. 186-193 8 p.

研究成果: ジャーナルへの寄稿記事

Roniviridae
Single-Chain Antibodies
Glycoproteins
Enzyme-Linked Immunosorbent Assay
Nidovirales
10 引用 (Scopus)

Chionaeosides A-D, triterpene saponins from Paronychia chionaea

Avunduk, S., Lacaille-Dubois, M. A., Miyamoto, T., Bedir, E., Şenol, S. G. & Çalişkan, Ö. A., 11 1 2007, : : Journal of Natural Products. 70, 11, p. 1830-1833 4 p.

研究成果: ジャーナルへの寄稿記事

Paronychia
Triterpenes
triterpenoid saponins
Saponins
Acids
4 引用 (Scopus)

Color reaction of 3,4-methylenedioxyamphetamines with chromotropic acid: Its improvement and application to the screening of seized tablets

Matsuda, K., Fukuzawa, T., Ishii, Y. & Yamada, H., 6 1 2007, : : Forensic Toxicology. 25, 1, p. 37-40 4 p.

研究成果: ジャーナルへの寄稿記事

3,4-Methylenedioxyamphetamine
N-Methyl-3,4-methylenedioxyamphetamine
Tablets
Screening
Color
9 引用 (Scopus)

Constituents of crinoidea. 5. Isolation and structure of a new glycosyl inositolphosphoceramide-type ganglioside from the feather star Comanthina schlegeli

Inagaki, M., Shiizaki, M., Hiwatashi, T., Miyamoto, T. & Higuchi, R., 11 1 2007, : : Chemical and Pharmaceutical Bulletin. 55, 11, p. 1649-1651 3 p.

研究成果: ジャーナルへの寄稿記事

Feathers
Gangliosides
Stars
Neuraminic Acids
Sphingosine
59 引用 (Scopus)
Chitinases
Muramidase
Tapes
Crystal structure
Substrates
9 引用 (Scopus)

Detection of weak ligand interactions of leukocyte Ig-like receptor B1 by fluorescence correlation spectroscopy

Kuroki, K., Kobayashi, S., Shiroishi, M., Kajikawa, M., Okamoto, N., Kohda, D. & Maenaka, K., 3 30 2007, : : Journal of Immunological Methods. 320, 1-2, p. 172-176 5 p.

研究成果: ジャーナルへの寄稿記事

Fluorescence Spectrometry
Leukocytes
Immunoglobulins
Ligands
HLA-G Antigens
17 引用 (Scopus)

Determination of pseudojujubogenin glycosides from Brahmi based on immunoassay using a monoclonal antibody against bacopaside I

Phrompittayarat, W., Putalun, W., Tanaka, H., Jetiyanon, K., Wlttaya-Areekul, S. & Ingkaninan, K., 9 1 2007, : : Phytochemical Analysis. 18, 5, p. 411-418 8 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
immunoassays
Immunoassay
glycosides
monoclonal antibodies
13 引用 (Scopus)

Determination of the absolute configuration of sialic acids in gangliosides from the sea cucumber Cucumaria echinata

Kisa, F., Yamada, K., Miyamoto, T., Inagaki, M. & Higuchi, R., 7 1 2007, : : Chemical and Pharmaceutical Bulletin. 55, 7, p. 1051-1052 2 p.

研究成果: ジャーナルへの寄稿記事

Cucumaria
Sea Cucumbers
Sialic Acids
Gangliosides
N-Acetylneuraminic Acid
18 引用 (Scopus)

Eastern blotting and immunoaffinity concentration using monoclonal antibody for ginseng saponins in the field of traditional Chinese medicines

Tanaka, H., Fukuda, N. & Shoyama, Y., 5 16 2007, : : Journal of Agricultural and Food Chemistry. 55, 10, p. 3783-3787 5 p.

研究成果: ジャーナルへの寄稿記事

Ginsenosides
Panax
Saponins
Chinese Traditional Medicine
saponins
9 引用 (Scopus)

Eastern blotting and use of anti-saikosaponin a monoclonal antibodies for detection of saikosaponins

Zhu, S. H., Morinaga, O., Shimokawa, S., Shon, T. K., Lee, S. C., Shoyama, Y. & Tanaka, H., 4 1 2007, : : Journal of Natural Medicines. 61, 2, p. 178-183 6 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Bovine Serum Albumin
Kampo Medicine
Quality Control
Quality control
57 引用 (Scopus)

Effect of buffer species on the unfolding and the aggregation of humanized IgG

Kameoka, D., Masuzaki, E., Ueda, T. & Imoto, T., 9 1 2007, : : Journal of Biochemistry. 142, 3, p. 383-391 9 p.

研究成果: ジャーナルへの寄稿記事

Buffers
Agglomeration
Immunoglobulin G
Morpholinos
Hot Temperature