研究成果 1976 2019

2007
13 引用 (Scopus)

Determination of the absolute configuration of sialic acids in gangliosides from the sea cucumber Cucumaria echinata

Kisa, F., Yamada, K., Miyamoto, T., Inagaki, M. & Higuchi, R., 7 1 2007, : : Chemical and Pharmaceutical Bulletin. 55, 7, p. 1051-1052 2 p.

研究成果: ジャーナルへの寄稿記事

Cucumaria
Sea Cucumbers
Sialic Acids
Gangliosides
N-Acetylneuraminic Acid
18 引用 (Scopus)

Eastern blotting and immunoaffinity concentration using monoclonal antibody for ginseng saponins in the field of traditional Chinese medicines

Tanaka, H., Fukuda, N. & Shoyama, Y., 5 16 2007, : : Journal of Agricultural and Food Chemistry. 55, 10, p. 3783-3787 5 p.

研究成果: ジャーナルへの寄稿記事

Ginsenosides
Panax
Saponins
Chinese Traditional Medicine
saponins
9 引用 (Scopus)

Eastern blotting and use of anti-saikosaponin a monoclonal antibodies for detection of saikosaponins

Zhu, S. H., Morinaga, O., Shimokawa, S., Shon, T. K., Lee, S. C., Shoyama, Y. & Tanaka, H., 4 1 2007, : : Journal of Natural Medicines. 61, 2, p. 178-183 6 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Bovine Serum Albumin
Kampo Medicine
Quality Control
Quality control
57 引用 (Scopus)

Effect of buffer species on the unfolding and the aggregation of humanized IgG

Kameoka, D., Masuzaki, E., Ueda, T. & Imoto, T., 9 1 2007, : : Journal of Biochemistry. 142, 3, p. 383-391 9 p.

研究成果: ジャーナルへの寄稿記事

Buffers
Agglomeration
Immunoglobulin G
Morpholinos
Hot Temperature
46 引用 (Scopus)

Effect of hydrogen and frequency on fatigue behavior of SCM435 steel for storage cylinder of hydrogen station

Tanaka, H., Homma, N., Matsuoka, S. & Murakami, Y., 12 2007, : : Nihon Kikai Gakkai Ronbunshu, A Hen/Transactions of the Japan Society of Mechanical Engineers, Part A. 73, 12, p. 1358-1365 8 p.

研究成果: ジャーナルへの寄稿記事

Steel
Hydrogen
Fatigue of materials
Fatigue crack propagation
Crack tips
1 引用 (Scopus)

Effect on the expression of testicular steroidogenic enzymes in fetal mouse by maternal exposure to TCDD

Mutoh, J., Ishida, T., Ishii, Y. & Yamada, H., 1 1 2007, : : Fukuoka igaku zasshi = Hukuoka acta medica. 98, 5, p. 203-207 5 p.

研究成果: ジャーナルへの寄稿記事

Maternal Exposure
Dioxins
Sexual Behavior
Enzymes
Inbred C57BL Mouse
40 引用 (Scopus)

Effects of various methoxyflavones on vincristine uptake and multidrug resistance to vincristine in P-gp-overexpressing K562/ADM cells

Ohtani, H., Ikegawa, T., Honda, Y., Kohyama, N., Morimoto, S., Shoyama, Y., Juichi, M., Naito, M., Tsuruo, T. & Sawada, Y., 10 1 2007, : : Pharmaceutical Research. 24, 10, p. 1936-1943 8 p.

研究成果: ジャーナルへの寄稿記事

Delta modulation
K562 Cells
Multiple Drug Resistance
Vincristine
flavone
12 引用 (Scopus)

Expression and purification of uniformly 15N-labeled amyloid β peptide 1-40 in Escherichia coli

Nagata-Uchiyama, M., Yaguchi, M., Hirano, Y. & Ueda, T., 8 1 2007, : : Protein and Peptide Letters. 14, 8, p. 788-792 5 p.

研究成果: ジャーナルへの寄稿記事

Amyloid beta-Peptides
Amyloid
Escherichia coli
Purification
Biomolecular Nuclear Magnetic Resonance
2 引用 (Scopus)

Expression of human IL-13 receptor α2 extracellular domain in Pichia pastoris

Ohkuri, T., Takeda, C., Yoshida, Y., Izuhara, K., Imoto, T. & Ueda, T., 11 1 2007, : : Protein Expression and Purification. 56, 1, p. 48-53 6 p.

研究成果: ジャーナルへの寄稿記事

Interleukin-13 Receptors
Pichia
Interleukin-13
P-Glycoprotein
Yeast
15 引用 (Scopus)

Flavonoids from Acacia pennata and their cyclooxygenase (COX-1 and COX-2) inhibitory activities

Dongmo, A. B., Miyamoto, T., Yoshikawa, K., Arihara, S. & Lacaille-Dubois, M. A., 9 1 2007, : : Planta Medica. 73, 11, p. 1202-1207 6 p.

研究成果: ジャーナルへの寄稿記事

Acacia
Apigenin
Cyclooxygenase 1
Quercetin
Prostaglandin-Endoperoxide Synthases
37 引用 (Scopus)

Identification and characterization of cannabinoids that induce cell death through mitochondrial permeability transition in cannabis leaf cells

Morimoto, S., Tanaka, Y., Sasaki, K., Tanaka, H., Fukamizu, T., Shoyama, Y., Shoyama, Y. & Taura, F., 7 13 2007, : : Journal of Biological Chemistry. 282, 28, p. 20739-20751 13 p.

研究成果: ジャーナルへの寄稿記事

Cannabinoids
Cell death
Cannabis
Permeability
Cell Death

Immunodetection of ginsenoside Rb1 in rat serum

Ma, L. L., Chao, Z., Tanaka, H. & Shoyama, Y., 1 1 2007, : : Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 27, 12, p. 1915-1917 3 p.

研究成果: ジャーナルへの寄稿記事

Membranes
Serum
Immunoassay
Monoclonal Antibodies
Hybridomas
39 引用 (Scopus)

Immunohistochemical localization of d-alanine to β-cells in rat pancreas

Morikawa, A., Hamase, K., Ohgusu, T., Etoh, S., Tanaka, H., Koshiishi, I., Shoyama, Y. & Zaitsu, K., 4 20 2007, : : Biochemical and Biophysical Research Communications. 355, 4, p. 872-876 5 p.

研究成果: ジャーナルへの寄稿記事

Alanine
Rats
Pancreas
Staining and Labeling
Amino Acids
84 引用 (Scopus)

Improvement of artemisinin production by chitosan in hairy root cultures of Artemisia annua L.

Putalun, W., Luealon, W., De-Eknamkul, W., Tanaka, H. & Shoyama, Y., 7 1 2007, : : Biotechnology letters. 29, 7, p. 1143-1146 4 p.

研究成果: ジャーナルへの寄稿記事

Artemisia annua
Chitosan
Yeast
Yeasts
artemisinine
16 引用 (Scopus)

Inhibitory effects of adenine nucleotides and related substances on UDP-glucuronosyltransferase: Structure-effect relationships and evidence for an allosteric mechanism

Nishimura, Y., Maeda, S., Ikushiro, S. I., Mackenzie, P. I., Ishii, Y. & Yamada, H., 11 1 2007, : : Biochimica et Biophysica Acta - General Subjects. 1770, 11, p. 1557-1566 10 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Adenine Nucleotides
Hymecromone
Adenine
Adenosine Monophosphate
39 引用 (Scopus)

Neuritogenic activity of gangliosides from echinoderms and their structure-activity relationship

Kaneko, M., Yamada, K., Miyamoto, T., Inagaki, M. & Higuchi, R., 3 1 2007, : : Chemical and Pharmaceutical Bulletin. 55, 3, p. 462-463 2 p.

研究成果: ジャーナルへの寄稿記事

Gangliosides
PC12 Cells
Nerve Growth Factor
Structure-Activity Relationship
Rats
14 引用 (Scopus)

New triterpenoidal saponins from Gypsophila repens

Elbandy, M., Miyamoto, T. & Lacaille-Dubois, M. A., 6 22 2007, : : Helvetica Chimica Acta. 90, 2, p. 260-270 11 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
glucosides
Triterpenes
Saponins
sugars
71 引用 (Scopus)

Novel miniature SPR immunosensor equipped with all-in-one multi-microchannel sensor chip for detecting low-molecular-weight analytes

Kim, S. J., Gobi, K. V., Iwasaka, H., Tanaka, H. & Miura, N., 12 15 2007, : : Biosensors and Bioelectronics. 23, 5, p. 701-707 7 p.

研究成果: ジャーナルへの寄稿記事

Immunosensors
2,4-Dichlorophenoxyacetic Acid
Surface Plasmon Resonance
Surface plasmon resonance
Microchannels
42 引用 (Scopus)
Immunosensors
2,4-Dichlorophenoxyacetic Acid
Ovalbumin
Surface plasmon resonance
surface plasmon resonance
23 引用 (Scopus)
Glycyrrhizic Acid
Immunosorbents
Chinese Traditional Medicine
Medicine
Assays
55 引用 (Scopus)

Pharmacological activities of crocin in saffron

Soeda, S., Ochiai, T., Shimeno, H., Saito, H., Abe, K., Tanaka, H. & Shoyama, Y., 4 1 2007, : : Journal of Natural Medicines. 61, 2, p. 102-111 10 p.

研究成果: ジャーナルへの寄稿評論記事

Sphingomyelin Phosphodiesterase
Oxidative stress
Pharmacology
Ceramides
Phosphorylation
41 引用 (Scopus)

Phytocannabiniods in Cannabis sativa: Recent studies on biosynthetic enzymes

Taura, F., Sirikantaramas, S., Shoyama, Y., Shoyama, Y. & Morimoto, S., 9 13 2007, : : Chemistry and Biodiversity. 4, 8, p. 1649-1663 15 p.

研究成果: ジャーナルへの寄稿評論記事

Enzymes
Oxidoreductases
Cannabinoids
13 引用 (Scopus)

Preparation of a novel monoclonal antibody against the antimalarial drugs, artemisinin and artesunate

Tanaka, H., Putalun, W., De-Eknamkul, W., Matangkasombut, O. & Shoyama, Y., 8 1 2007, : : Planta Medica. 73, 10, p. 1127-1132 6 p.

研究成果: ジャーナルへの寄稿記事

Antimalarials
Monoclonal Antibodies
dihydroartemisinin
Artemisia annua
Enzyme-Linked Immunosorbent Assay
23 引用 (Scopus)

Production of Δ1-tetrahydrocannabinolic acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris

Taura, F., Dono, E., Sirikantaramas, S., Yoshimura, K., Shoyama, Y. & Morimoto, S., 9 28 2007, : : Biochemical and Biophysical Research Communications. 361, 3, p. 675-680 6 p.

研究成果: ジャーナルへの寄稿記事

Pichia
Acids
Enzymes
Dronabinol
Glycoside Hydrolases
161 引用 (Scopus)

Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo

Ochiai, T., Shimeno, H., Mishima, K. I., Iwasaki, K., Fujiwara, M., Tanaka, H., Shoyama, Y., Toda, A., Eyanagi, R. & Soeda, S., 4 1 2007, : : Biochimica et Biophysica Acta - General Subjects. 1770, 4, p. 578-584 7 p.

研究成果: ジャーナルへの寄稿記事

Carotenoids
Wounds and Injuries
Esters
PC12 Cells
Pigments
28 引用 (Scopus)

Protein-protein interactions between rat hepatic cytochromes P450 (P450s) and UDP-glucuronosyltransferases (UGTs): evidence for the functionally active UGT in P450-UGT complex.

Ishii, Y., Iwanaga, M., Nishimura, Y., Takeda, S., Ikushiro, S. I., Nagata, K., Yamazoe, Y., Mackenzie, P. I. & Yamada, H., 10 2007, : : Drug metabolism and pharmacokinetics. 22, 5, p. 367-376 10 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Cytochrome P-450 Enzyme System
Liver
Proteins
Protein Isoforms
38 引用 (Scopus)

Recent advances in Cannabis sativa research: Biosynthetic studies and its potential in biotechnology

Sirikantaramas, S., Taura, F., Morimoto, S. & Shoyama, Y., 8 1 2007, : : Current Pharmaceutical Biotechnology. 8, 4, p. 237-243 7 p.

研究成果: ジャーナルへの寄稿評論記事

Cannabis
Biotechnology
Cannabinoids
Acids
Research
23 引用 (Scopus)

Reduced pain behaviors and extracellular signal-related protein kinase activation in primary sensory neurons by peripheral tissue injury in mice lacking platelet-activating factor receptor

Tsuda, M., Ishii, S., Masuda, T., Hasegawa, S., Nakamura, K., Nagata, K., Yamashita, T., Furue, H., Tozaki-Saitoh, H., Yoshimura, M., Koizumi, S., Shimizu, T. & Inoue, K., 9 1 2007, : : Journal of Neurochemistry. 102, 5, p. 1658-1668 11 p.

研究成果: ジャーナルへの寄稿記事

Sensory Receptor Cells
Protein Kinases
Neurons
Chemical activation
Tissue
8 引用 (Scopus)

Saponins from the roots of Nylandtia spinosa

Diome, C., Mitaine-Offer, A. C., Miyamoto, T., Delaude, C., Mirjolet, J. F., Duchamp, O. & Lacaille-Dubois, M. A., 10 1 2007, : : Journal of Natural Products. 70, 10, p. 1680-1682 3 p.

研究成果: ジャーナルへの寄稿記事

Saponins
saponins
Esters
esters
Triterpenes
15 引用 (Scopus)

Stable supply of large amounts of human Fab from the inclusion bodies in E. coli

Fujii, T., Ohkuri, T., Onodera, R. & Ueda, T., 5 1 2007, : : Journal of Biochemistry. 141, 5, p. 699-707 9 p.

研究成果: ジャーナルへの寄稿記事

Inclusion Bodies
Escherichia coli
Urea
Cystamine
Cysteamine
29 引用 (Scopus)

Steroidal saponins from Asparagus acutifolius

Sautour, M., Miyamoto, T. & Lacaille-Dubois, M. A., 10 1 2007, : : Phytochemistry. 68, 20, p. 2554-2562 9 p.

研究成果: ジャーナルへの寄稿記事

Asparagus acutifolius
Spirostans
steroid saponins
Spectroscopic analysis
Saponins
34 引用 (Scopus)

Structural consequences of mutations in interfacial Tyr residues of a protein antigen-antibody complex: The case of HyHEL-10-HEL

Shiroishi, M., Tsumoto, K., Tanaka, Y., Yokota, A., Nakanishi, T., Kondo, H. & Kumagai, I., 3 2 2007, : : Journal of Biological Chemistry. 282, 9, p. 6783-6791 9 p.

研究成果: ジャーナルへの寄稿記事

Antigen-Antibody Complex
Antigens
Mutation
Antibodies
Antibody Specificity
75 引用 (Scopus)

Structure and function of DnaA N-terminal domains: Specific sites and mechanisms in inter-DnaA interaction and in DnaB helicase loading on oriC

Abe, Y., Jo, T., Matsuda, Y., Matsunaga, C., Katayama, T. & Ueda, T., 6 15 2007, : : Journal of Biological Chemistry. 282, 24, p. 17816-17827 12 p.

研究成果: ジャーナルへの寄稿記事

DnaB Helicases
Dimerization
Single-Stranded DNA
Nuclear magnetic resonance
DNA
16 引用 (Scopus)

Sulfated lupane triterpene derivatives and a flavone C-glycoside from Gypsophila repens

Elbandy, M., Miyamoto, T. & Lacaille-Dubois, M. A., 5 1 2007, : : Chemical and Pharmaceutical Bulletin. 55, 5, p. 808-811 4 p.

研究成果: ジャーナルへの寄稿記事

flavone
Triterpenes
Derivatives
Esters
Luteolin
26 引用 (Scopus)

Suppression of fetal testicular cytochrome P450 17 by maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: A mechanism involving an initial effect on gonadotropin synthesis in the pituitary

Taketoh, J., Mutoh, J., Takeda, T., Ogishima, T., Takeda, S., Ishii, Y., Ishida, T. & Yamada, H., 3 13 2007, : : Life Sciences. 80, 14, p. 1259-1267 9 p.

研究成果: ジャーナルへの寄稿記事

Maternal Exposure
Gonadotropins
Cytochrome P-450 Enzyme System
Luteinizing Hormone
Multifetal Pregnancy Reduction
30 引用 (Scopus)

The EGFR inhibitor gefitinib suppresses ligand-stimulated endocytosis of EGFR via the early/late endocytic pathway in non-small cell lung cancer cell lines

Nishimura, Y., Bereczky, B. & Ono, M., 5 1 2007, : : Histochemistry and Cell Biology. 127, 5, p. 541-553 13 p.

研究成果: ジャーナルへの寄稿記事

Endocytosis
Non-Small Cell Lung Carcinoma
Ligands
Endosomes
Cell Line
91 引用 (Scopus)

The interaction of DiaA and DnaA regulates the replication cycle in E. coli by directly promoting ATP-DnaA-specific initiation complexes

Keyamura, K., Fujikawa, N., Ishida, T., Ozaki, S., Su'etsugu, M., Fujimitsu, K., Kagawa, W., Yokoyama, S., Kurumizaka, H. & Katayama, T., 8 15 2007, : : Genes and Development. 21, 16, p. 2083-2099 17 p.

研究成果: ジャーナルへの寄稿記事

Adenosine Triphosphate
Escherichia coli
Adenosine Diphosphate
Cell Cycle
Mutant Proteins
10 引用 (Scopus)

Ursane-type triterpene saponins from Zygophyllum geslini

Smati, D., Mitaine-Offer, A. C., Miyamoto, T., Hammiche, V. & Lacaille-Dubois, M. A., 6 26 2007, : : Helvetica Chimica Acta. 90, 4, p. 712-719 8 p.

研究成果: ジャーナルへの寄稿記事

Zygophyllum
Glycosides
glucosides
Triterpenes
Saponins
2006
2 引用 (Scopus)

Activation of a refolded, berberine-specific, single-chain Fv fragment by addition of free berberine

Kim, J. S., Masaki, T., Sirikantaramas, S., Shoyama, Y. & Tanaka, H., 7 1 2006, : : Biotechnology letters. 28, 13, p. 999-1006 8 p.

研究成果: ジャーナルへの寄稿記事

Immunoglobulin Variable Region
Berberine
Single-Chain Antibodies
Assays
Enzymes
16 引用 (Scopus)

Amyloid formation in denatured single-mutant lysozymes where residual structures are modulated

Mishima, T., Ohkuri, T., Monji, A., Imoto, T. & Ueda, T., 10 9 2006, : : Protein Science. 15, 10, p. 2448-2452 5 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Amyloid
Ports and harbors
Spectrum Analysis
Fluorescence

Analysis of internal motions of RNase T1 complexed with a productive substrate involving 15N NMR relaxation measurements

Yoshida, Y., Tanaka, M., Ohkuri, T., Tanaka, Y., Imoto, T. & Ueda, T., 7 1 2006, : : Journal of biochemistry. 140, 1, p. 43-48 6 p.

研究成果: ジャーナルへの寄稿記事

Ribonuclease T1
Nuclear magnetic resonance
Substrates
Guanosine
Linewidth
14 引用 (Scopus)

A new oleanane glycoside from the roots of Astragalus caprinus

Mitaine-Offer, A. C., Miyamoto, T., Semmar, N., Jay, M. & Lacaille-Dubois, M. A., 7 1 2006, : : Magnetic Resonance in Chemistry. 44, 7, p. 713-716 4 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
glucosides
Mass spectrometry
mass spectroscopy
Nuclear magnetic resonance
22 引用 (Scopus)

An isolated Hda-clamp complex is functional in the regulatory inactivation of DnaA and DNA replication

Kawakami, H., Su'etsugu, M. & Katayama, T., 10 1 2006, : : Journal of structural biology. 156, 1, p. 220-229 10 p.

研究成果: ジャーナルへの寄稿記事

DNA Replication
Holoenzymes
DNA Polymerase III
Hydrolysis
Adenosine Triphosphate
28 引用 (Scopus)

A novel analytical ELISA-based methodology for pharmacologically active saikosaponins

Zhu, S., Shimokawa, S., Shoyama, Y. & Tanaka, H., 2 1 2006, : : Fitoterapia. 77, 2, p. 100-108 9 p.

研究成果: ジャーナルへの寄稿記事

Enzyme-Linked Immunosorbent Assay
Aminopterin
Monoclonal Antibodies
Kampo Medicine
Hypoxanthine
32 引用 (Scopus)

A role of LIM kinase 1/cofilin pathway in regulating endocytic trafficking of EGF receptor in human breast cancer cells

Nishimura, Y., Yoshioka, K., Bernard, O., Bereczky, B. & Itoh, K., 11 1 2006, : : Histochemistry and Cell Biology. 126, 5, p. 627-638 12 p.

研究成果: ジャーナルへの寄稿記事

Cofilin 1
Lim Kinases
Epidermal Growth Factor Receptor
Epidermal Growth Factor
Breast Neoplasms
3 引用 (Scopus)

A simple search of TM segments in polytopic membrane protein using matrix-assisted laser desorption ionization time-of-flight mass spectrometry

Abe, Y., Hamasaki, T., Turusaki, S., Takazaki, S., Jin, X., Kang, D. & Hamasaki, N., 8 7 2006, : : Protein and Peptide Letters. 13, 8, p. 761-767 7 p.

研究成果: ジャーナルへの寄稿記事

Ionization
Mass spectrometry
Desorption
Mass Spectrometry
Membrane Proteins
14 引用 (Scopus)

Bioactive steroidal saponins from Smilax medica

Sautour, M., Miyamoto, T. & Lacaille-Dubois, M. A., 6 1 2006, : : Planta medica. 72, 7, p. 667-670 4 p.

研究成果: ジャーナルへの寄稿記事

Smilax
Spirostans
steroid saponins
Candida glabrata
Candida tropicalis
25 引用 (Scopus)

Biologically active glycosides from asteroidea, 42. Isolation and structure of a new biologically active ganglioside molecular species from the starfish Asterina pectinifera

Higuchi, R., Inoue, S., Inagaki, K., Sakai, M., Miyamoto, T., Komori, T., Inagaki, M. & Isobe, R., 3 1 2006, : : Chemical and Pharmaceutical Bulletin. 54, 3, p. 287-291 5 p.

研究成果: ジャーナルへの寄稿記事

Asterina
Starfish
Gangliosides
Glycosides
endoglycoceramidase
18 引用 (Scopus)

Constituents of holothuroidea, 17. Isolation and structure of biologically active monosialo-gangliosides from the sea cucumber Cucumaria echinata

Kisa, F., Yamada, K., Miyamoto, T., Inagaki, M. & Higuchi, R., 7 12 2006, : : Chemical and Pharmaceutical Bulletin. 54, 7, p. 982-987 6 p.

研究成果: ジャーナルへの寄稿記事

Cucumaria
Sea Cucumbers
Gangliosides
phytosphingosine
Ceramides
15 引用 (Scopus)

Constituents of holothuroidea, 18.1 isolation and structure of biologically active disialo- and trisialo-gangliosides from the sea cucumber Cucumaria echinata

Kisa, F., Yamada, K., Miyamoto, T., Inagaki, M. & Higuchi, R., 9 14 2006, : : Chemical and Pharmaceutical Bulletin. 54, 9, p. 1293-1298 6 p.

研究成果: ジャーナルへの寄稿記事

Cucumaria
Sea Cucumbers
Gangliosides
phytosphingosine
Ceramides