研究成果 1976 2020

2004
21 引用 (Scopus)
Feathers
Gangliosides
Stars
Sphingosine
PC12 Cells
46 引用 (Scopus)

Continuous flow immunosensor for highly selective and real-time detection of sub-ppb levels of 2-hydroxybiphenyl by using surface plasmon resonance imaging

Gobi, K. V., Tanaka, H., Shoyama, Y. & Miura, N., 9 15 2004, : : Biosensors and Bioelectronics. 20, 2, p. 350-357 8 p.

研究成果: ジャーナルへの寄稿記事

Immunosensors
Surface Plasmon Resonance
Surface plasmon resonance
Imaging techniques
Sensors
89 引用 (Scopus)

Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signaling by increasing glutathione synthesis

Ochiai, T., Soeda, S., Ohno, S., Tanaka, H., Shoyama, Y. & Shimeno, H., 4 2004, : : Neurochemistry International. 44, 5, p. 321-330 10 p.

研究成果: ジャーナルへの寄稿記事

Sphingomyelin Phosphodiesterase
Ceramides
Glutathione
Phosphotransferases
Glucose
171 引用 (Scopus)

Crocin prevents the death of rat pheochromyctoma (PC-12) cells by its antioxidant effects stronger than those of α-tocopherol

Ochiai, T., Ohno, S., Soeda, S., Tanaka, H., Shoyama, Y. & Shimeno, H., 5 13 2004, : : Neuroscience Letters. 362, 1, p. 61-64 4 p.

研究成果: ジャーナルへの寄稿記事

Tocopherols
Antioxidants
Glucose
Superoxide Dismutase
Serum
9 引用 (Scopus)

Curcumin anticipates the suppressed body weight gain with 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice

Ishida, T., Taketoh, J., Nakatsune, E., Kan-o, S., Naito, E., Takeda, S., Mutoh, J., Ishii, Y. & Yamada, H., 10 1 2004, : : Journal of Health Science. 50, 5, p. 474-482 9 p.

研究成果: ジャーナルへの寄稿記事

Curcumin
Weight Gain
Body Weight
Toxicity
Liver
18 引用 (Scopus)
Glucuronosyltransferase
Methylcholanthrene
Microsomes
Cytochrome P-450 Enzyme System
Liver
25 引用 (Scopus)

Determination of the complete cDNA sequence, construction of expression systems, and elucidation of fibrinolytic activity for Tapes japonica lysozyme

Takeshita, K., Hashimoto, Y., Thujihata, Y., So, T., Ueda, T. & Iomoto, T., 8 1 2004, : : Protein Expression and Purification. 36, 2, p. 254-262 9 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Complementary DNA
Invertebrates
Chitinases
Pichia
25 引用 (Scopus)

Development of an assay system for saikosaponin a using anti-saikosaponin a monoclonal antibodies

Zhu, S. H., Shimokawa, S. I., Tanaka, H. & Shoyama, Y., 1 1 2004, : : Biological and Pharmaceutical Bulletin. 27, 1, p. 66-71 6 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Enzyme-Linked Immunosorbent Assay
Hybridomas
Bovine Serum Albumin
Aminopterin
17 引用 (Scopus)

Development of a one-step immunochromatographic strip test for the detection of sennosides A and B

Putalun, W., Morinaga, O., Tanaka, H. & Shoyama, Y., 3 1 2004, : : Phytochemical Analysis. 15, 2, p. 112-116 5 p.

研究成果: ジャーナルへの寄稿記事

immunoaffinity chromatography
detectors
Detectors
antibodies
Serum Albumin
5 引用 (Scopus)

Development of monoclonal antibody against isoquinoline alkaloid coptisine and its application for the screening of medicinal plants

Kim, J. S., Tanaka, H., Yuan, C. S. & Shoyama, Y., 12 1 2004, : : Cytotechnology. 44, 3, p. 115-123 9 p.

研究成果: ジャーナルへの寄稿記事

Alkaloids
Monoclonal antibodies
Medicinal Plants
Assays
Screening

Development of rapid and sensitive screening methods for natural products using specific monoclonal antibodies

Tanaka, H., 1 1 2004, : : Fukuoka igaku zasshi = Hukuoka acta medica. 95, 8, p. 173-182 10 p.

研究成果: ジャーナルへの寄稿評論記事

Diagnostic Reagent Kits
Chinese Herbal Drugs
Glycyrrhizic Acid
Anthraquinones
Biological Products
86 引用 (Scopus)

DiaA, a novel DnaA-binding protein, ensures the timely initiation of Escherichia coli chromosome replication

Ishida, T., Akimitsu, N., Kashioka, T., Hatano, M., Kubota, T., Ogata, Y., Sekimizu, K. & Katayama, T., 10 29 2004, : : Journal of Biological Chemistry. 279, 44, p. 45546-45555 10 p.

研究成果: ジャーナルへの寄稿記事

Chromosomes
Escherichia coli
Carrier Proteins
Flow cytometry
Dimers
171 引用 (Scopus)

Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts

Eskelinen, E. L., Schmidt, C. K., Neu, S., Willenborg, M., Fuertes, G., Salvador, N., Tanaka, Y., Lüllmann-Rauch, R., Hartmann, D., Heeren, J., Von Figura, K., Knecht, E. & Saftig, P., 7 1 2004, : : Molecular biology of the cell. 15, 7, p. 3132-3145 14 p.

研究成果: ジャーナルへの寄稿記事

Autophagy
Fibroblasts
Cholesterol
Vacuoles
Proteolysis
121 引用 (Scopus)

Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux

Honda, Y., Ushigome, F., Koyabu, N., Morimoto, S., Shoyama, Y., Uchiumi, T., Kuwano, M., Ohtani, H. & Sawada, Y., 12 1 2004, : : British Journal of Pharmacology. 143, 7, p. 856-864 9 p.

研究成果: ジャーナルへの寄稿記事

Citrus paradisi
P-Glycoprotein
Saquinavir
Vinblastine
Pharmaceutical Preparations
97 引用 (Scopus)

Endocannabinoid system modulates relapse to methamphetamine seeking: Possible mediation by the arachidonic acid cascade

Anggadiredja, K., Nakamichi, M., Hiranita, T., Tanaka, H., Shoyama, Y., Watanabe, S. & Yamamoto, T., 8 1 2004, : : Neuropsychopharmacology. 29, 8, p. 1470-1478 9 p.

研究成果: ジャーナルへの寄稿記事

Endocannabinoids
Methamphetamine
Arachidonic Acid
Recurrence
Cues
3 引用 (Scopus)

Foefidissimosides C-F, novel glycosides from the roots of Cucurbita foetidissima

Gaidi, G., Miyamoto, T., Lerche, H. & Lacaille-Dubois, M. A., 7 8 2004, : : Helvetica Chimica Acta. 87, 5, p. 1158-1166 9 p.

研究成果: ジャーナルへの寄稿記事

Glycosides
Cucurbita
glucosides
acids
Acids
20 引用 (Scopus)

Glandulosides A-D, triterpene saponins from Acanthophyllum glandulosum

Gaidi, G., Miyamoto, T., Ramezani, M. & Lacaille-Dubois, M. A., 7 1 2004, : : Journal of Natural Products. 67, 7, p. 1114-1118 5 p.

研究成果: ジャーナルへの寄稿記事

Acanthophyllum
Triterpenes
triterpenoid saponins
Saponins
Homo
189 引用 (Scopus)

Glucuronidation and the UDP-glucuronosyltransferases in health and disease

Wells, P. G., Mackenzie, P. I., Chowdhury, J. R., Guillemette, C., Gregory, P. A., Ishii, Y., Hansen, A. J., Kessler, F. K., Kim, P. M., Chowdhury, N. R. & Ritter, J. K., 3 1 2004, : : Drug Metabolism and Disposition. 32, 3, p. 281-290 10 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Health
Neoplasm Genes
Xenobiotics
Genetic Therapy
31 引用 (Scopus)

Immunoquantitative analysis for berberine and its related compounds using monoclonal antibodies in herbal medicines

Kim, J. S., Tanaka, H. & Shoyama, Y., 1 1 2004, : : Analyst. 129, 1, p. 87-91 5 p.

研究成果: ジャーナルへの寄稿記事

Berberine
Monoclonal antibodies
Herbal Medicine
antibody
Monoclonal Antibodies
59 引用 (Scopus)

Inhibition of S-Phase Cyclin-Dependent Kinase Activity Blocks Expression of Epstein-Barr Virus Immediate-Early and Early Genes, Preventing Viral Lytic Replication

Kudoh, A., Daikoku, T., Sugaya, Y., Isomura, H., Fujita, M., Kiyono, T., Nishiyama, Y. & Tsurumi, T., 1 1 2004, : : Journal of virology. 78, 1, p. 104-115 12 p.

研究成果: ジャーナルへの寄稿記事

Human herpesvirus 4
Viral Genes
cyclin-dependent kinase
Cyclin-Dependent Kinases
Human Herpesvirus 4
11 引用 (Scopus)

Isolation and structure of a GD3-type ganglioside molecular species possessing neuritogenic activity from the starfish Luidia maculata

Kawatake, S., Inagaki, M., Isobe, R., Miyamoto, T. & Higuchi, R., 8 1 2004, : : Chemical and Pharmaceutical Bulletin. 52, 8, p. 1002-1004 3 p.

研究成果: ジャーナルへの寄稿記事

Starfish
phytosphingosine
Ceramides
Hydroxy Acids
Gangliosides
28 引用 (Scopus)

Legionella dumoffii DjlA, a member of the DnaJ family, is required for intracellular growth

Ohnishi, H., Mizunoe, Y., Takade, A., Tanaka, Y., Miyamoto, H., Harada, M. & Yoshida, S. I., 6 1 2004, : : Infection and Immunity. 72, 6, p. 3592-3603 12 p.

研究成果: ジャーナルへの寄稿記事

Legionella
Phagosomes
Macrophages
Growth
Transmission Electron Microscopy
15 引用 (Scopus)

LIM kinase 1: Evidence for a role in the regulation of intracellular vesicle trafficking of lysosomes and endosomes in human breast cancer cells

Nishimura, Y., Yoshioka, K., Bernard, O., Himeno, M. & Itoh, K., 8 2004, : : European Journal of Cell Biology. 83, 7, p. 369-380 12 p.

研究成果: ジャーナルへの寄稿記事

Lim Kinases
Endosomes
Lysosomes
Breast Neoplasms
Epidermal Growth Factor

Lysosomal storage disease

Tanaka, Y., Fujita, H. & Himeno, M., 5 2004, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 49, 7 Suppl, p. 1143-1144 2 p.

研究成果: ジャーナルへの寄稿評論記事

Mannosephosphates
Sphingolipidoses
Mucolipidoses
Lysosomal Storage Diseases
Sulfatases
39 引用 (Scopus)

Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B

Fujita, H., Umezuki, Y., Imamura, K., Ishikawa, D., Uchimura, S., Nara, A., Yoshimori, T., Hayashizaki, Y., Kawai, J., Ishidoh, K., Tanaka, Y. & Himeno, M., 6 15 2004, : : Journal of Cell Science. 117, 14, p. 2997-3009 13 p.

研究成果: ジャーナルへの寄稿記事

Protein Transport
Adenosine Triphosphatases
Membranes
Proteins
Endosomes
13 引用 (Scopus)

Massspectrometric analyses of transmembrane proteins in human erythrocyte membrane

Abe, Y., Chaen, T., Jin, X. R., Hamasaki, T. & Hamasaki, N., 7 1 2004, : : Journal of biochemistry. 136, 1, p. 97-106 10 p.

研究成果: ジャーナルへの寄稿記事

Erythrocyte Membrane
Membrane Proteins
Membranes
Peptide Mapping
Proteins
48 引用 (Scopus)

Modulation of compactness and long-range interactions of unfolded lysozyme by single point mutations

Wirmer, J., Schlörb, C., Klein-Seetharaman, J., Hirano, R., Ueda, T., Imoto, T. & Schwalbe, H., 11 5 2004, : : Angewandte Chemie - International Edition. 43, 43, p. 5780-5785 6 p.

研究成果: ジャーナルへの寄稿記事

Mutagenesis
Muramidase
Nuclear magnetic resonance spectroscopy
Enzymes
Modulation
50 引用 (Scopus)
Escherichia coli Proteins
DNA Replication
Adenosine Triphosphate
DNA
Hydrolysis
9 引用 (Scopus)

New Acylated Presenegenin Saponins from Two Species of Muraltia

Elbandy, M., Miyamoto, T., Delaude, C. & Lacaille-Dubois, M. A., 4 22 2004, : : Helvetica Chimica Acta. 87, 2, p. 340-348 9 p.

研究成果: ジャーナルへの寄稿記事

Saponins
Isomers
esters
Esters
isomers
15 引用 (Scopus)

New Triterpene Saponins from Acanthophyllum pachystegium

Haddad, M., Miyamoto, T., Ramezani, M. & Lacaille-Dubois, M. A., 2004, : : Helvetica Chimica Acta. 87, 1, p. 73-81 9 p.

研究成果: ジャーナルへの寄稿記事

Triterpenes
Saponins
esters
Esters
acids
23 引用 (Scopus)

New triterpenoidal saponins acylated with monoterpenic acid from Albizia adianthifolia

Haddad, M., Miyamoto, T. & Lacaille-Dubois, M. A., 7 8 2004, : : Helvetica Chimica Acta. 87, 5, p. 1228-1238 11 p.

研究成果: ジャーナルへの寄稿記事

Albizzia
Saponins
esters
Esters
acids
12 引用 (Scopus)

Novel heat shock protein HspQ stimulates the degradation of mutant DnaA protein in Escherichia coli

Shimuta, T. R., Nakano, K., Yamaguchi, Y., Ozaki, S., Fujimitsu, K., Matsunaga, C., Noguchi, K., Emoto, A. & Katayama, T., 12 1 2004, : : Genes to Cells. 9, 12, p. 1151-1166 16 p.

研究成果: ジャーナルへの寄稿記事

Mutant Proteins
Heat-Shock Proteins
Escherichia coli
Shock
Proteins
1 引用 (Scopus)

Prevention of PC-12 cell death by crocin via sphingomyelinase-ceramide signaling by increase of glutathione biosynthesis

Ochiai, T., Soeda, S., Ohno, S., Shimeno, H., Tanaka, H., Shoyama, Y., Molnar, J., Berek, L. & Bartok, T., 5 31 2004, I International Symposium on Saffron Biology and Biotechnology. International Society for Horticultural Science, p. 423-434 12 p. (Acta Horticulturae; 巻数 650).

研究成果: 著書/レポートタイプへの貢献会議での発言

ceramides
cell death
glutathione
biosynthesis
phosphotransferases (kinases)
17 引用 (Scopus)

Production of monoclonal antibody against ginkgolic acids in Ginkgo biloba Linn

Loungratana, P., Tanaka, H. & Shoyama, Y., 8 4 2004, : : American Journal of Chinese Medicine. 32, 1, p. 33-48 16 p.

研究成果: ジャーナルへの寄稿記事

Ginkgo biloba
Monoclonal Antibodies
Enzyme-Linked Immunosorbent Assay
Salicylic Acid
Bovine Serum Albumin
12 引用 (Scopus)

Reactivation of DnaA by DNA sequence-specific nucleotide exchange in vitro

Fujimitsu, K. & Katayama, T., 9 17 2004, : : Biochemical and Biophysical Research Communications. 322, 2, p. 411-419 9 p.

研究成果: ジャーナルへの寄稿記事

DNA sequences
Nucleotides
Adenosine Triphosphate
Adenosine Diphosphate
DNA
9 引用 (Scopus)

Reduction of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice using an antiulcer drug, geranylgeranylacetone

Ishida, T., Oshimo, T., Nishimura, A., Mutoh, J., Ishii, Y., Koga, N., Yamada, H., Hashiguchi, I., Akamine, A. & Oguri, K., 9 1 2004, : : Biological and Pharmaceutical Bulletin. 27, 9, p. 1397-1402 6 p.

研究成果: ジャーナルへの寄稿記事

geranylgeranylacetone
Pharmaceutical Preparations
Maternal Exposure
Cytochrome P-450 CYP1A1
Dioxins
19 引用 (Scopus)

Sensitive Detection of Glycyrrhizin and Evaluation of the Affinity Constants by a Surface Plasmon Resonance-based Immunosensor

Sakai, T., Shinahara, K., Torimaru, A., Tanaka, H., Shoyama, Y. & Matsumoto, K., 2 2004, : : analytical sciences. 20, 2, p. 279-283 5 p.

研究成果: ジャーナルへの寄稿記事

Glycyrrhizic Acid
Immunosensors
Surface plasmon resonance
Bovine Serum Albumin
12 引用 (Scopus)

Simultaneous expression of guinea pig UDP-glucuronosyltransferase 2B21 (UGT2B21) and 2B22 in COS-7 cells enhances UGT2B21-catalyzed chloramphenicol glucuronidation

Ishii, Y., Miyoshi, A., Maji, D., Yamada, H. & Oguri, K., 10 1 2004, : : Drug Metabolism and Disposition. 32, 10, p. 1057-1060 4 p.

研究成果: ジャーナルへの寄稿記事

COS Cells
Chloramphenicol
Guinea Pigs
Oligomers
Morphine
16 引用 (Scopus)

Solasodine glycoside production by hairy root cultures of Physalis minima Linn.

Putalun, W., Prasarnsiwamai, P., Tanaka, H. & Shoyama, Y., 4 1 2004, : : Biotechnology letters. 26, 7, p. 545-548 4 p.

研究成果: ジャーナルへの寄稿記事

Physalis
Glycosides
Agrobacterium
Sugar (sucrose)
Sucrose
128 引用 (Scopus)

The gene controlling marijuana psychoactivity. Molecular cloning and heterologous expression of Δ1-tetrahydrocannabinolic acid synthase from Cannabis sativa L.

Sirikantaramas, S., Morimoto, S., Shoyama, Y., Ishikawa, Y., Wada, Y., Shoyama, Y. & Taura, F., 9 17 2004, : : Journal of Biological Chemistry. 279, 38, p. 39767-39774 8 p.

研究成果: ジャーナルへの寄稿記事

Cloning
Molecular Cloning
Cannabis
Genes
Flavin-Adenine Dinucleotide

The role of lysosomal membrane glycoproteins

Kuronita, T., Himeno, M. & Tanaka, Y., 5 2004, : : Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 49, 7 Suppl, p. 1027-1028 2 p.

研究成果: ジャーナルへの寄稿評論記事

CD Antigens
Lysosome-Associated Membrane Glycoproteins
CD36 Antigens
Sialoglycoproteins
Phagosomes
2003
17 引用 (Scopus)

(-)-Axinyssene: A novel cytotoxic diterpene from a Japanese marine sponge Axinyssa sp

Kodama, K., Higuchi, R., Miyamoto, T. & Van Soest, R. W. M., 1 23 2003, : : Organic Letters. 5, 2, p. 169-171 3 p.

研究成果: ジャーナルへの寄稿記事

leukemias
Diterpenes
Military Personnel
Porifera
methylene
12 引用 (Scopus)

1,3-Dimethylisoguaninium, an antiangiogenic purine analog from the sponge Amphimedon paraviridis

Jeong, S. J., Inagaki, M., Higuchi, R., Miyamoto, T., Ono, M., Kuwano, M. & Van Soest, R. W. M., 6 2003, : : Chemical and Pharmaceutical Bulletin. 51, 6, p. 731-733 3 p.

研究成果: ジャーナルへの寄稿記事

Endothelial cells
Porifera
Aorta
Endothelial Cells
Fibroblast Growth Factor 2
16 引用 (Scopus)

Acylated preatroxigenin glycosides from Atroxima congolana

Elbandy, M., Miyamoto, T., Delaude, C. & Lacaille-Dubois, M. A., 9 1 2003, : : Journal of Natural Products. 66, 9, p. 1154-1158 5 p.

研究成果: ジャーナルへの寄稿記事

Saponins
Glycosides
Isomers
glycosides
Spectroscopic analysis
100 引用 (Scopus)

A dominant negative form of the AAA ATPase SKD1/VPS4 impairs membrane trafficking out of endosomal/lysosomal compartments: Class E vps phenotype in mammalian cells

Fujita, H., Yamanaka, M., Imamura, K., Tanaka, Y., Nara, A., Yoshimori, T., Yokota, S. & Himeno, M., 1 15 2003, : : Journal of Cell Science. 116, 2, p. 401-414 14 p.

研究成果: ジャーナルへの寄稿評論記事

Endosomes
Lysosomes
Adenosine Triphosphatases
Phenotype
Membranes
26 引用 (Scopus)
endoproteinase Asp-N
Asparagine
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Muramidase
Viperidae
31 引用 (Scopus)

Anti-solasodine glycoside single-chain Fv antibody stimulates biosynthesis of solasodine glycoside in plants

Putalun, W., Taura, F., Qing, W., Matsushita, H., Tanaka, H. & Shoyama, Y., 12 1 2003, : : Plant Cell Reports. 22, 5, p. 344-349 6 p.

研究成果: ジャーナルへの寄稿記事

Solanum aculeatissimum
glycosides
genetically modified organisms
biosynthesis
antibodies
41 引用 (Scopus)

A quantitative ELISA using monoclonal antibody to survey paeoniflorin and albiflorin in crude drugs and traditional Chinese herbal medicines

Lu, Z., Morinaga, O., Tanaka, H. & Shoyama, Y., 6 2003, : : Biological and Pharmaceutical Bulletin. 26, 6, p. 862-866 5 p.

研究成果: ジャーナルへの寄稿評論記事

Herbal Medicine
Enzyme-Linked Immunosorbent Assay
Monoclonal Antibodies
Paeonia
Pharmaceutical Preparations
36 引用 (Scopus)

A small chimerically bifunctional monomeric protein: Tapes japonica lysozyme

Takeshita, K., Hashimoto, Y., Ueda, T. & Imoto, T., 9 1 2003, : : Cellular and Molecular Life Sciences. 60, 9, p. 1944-1951 8 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Chitinases
Proteins
Leeches
Serine Proteinase Inhibitors
417 引用 (Scopus)

At the acidic edge: Emerging functions for lysosomal membrane proteins

Eskelinen, E. L., Tanaka, Y. & Saftig, P., 3 1 2003, : : Trends in Cell Biology. 13, 3, p. 137-145 9 p.

研究成果: ジャーナルへの寄稿評論記事

Lysosome-Associated Membrane Glycoproteins
Autophagy
Glycogen Storage Disease Type IIb
Sialic Acid Storage Disease
Proteins