研究成果 1976 2019

1996
20 引用 (Scopus)
3,4,5,3',4'-pentachlorobiphenyl
Selenium-Binding Proteins
Methylcholanthrene
Polychlorinated Biphenyls
Liver
17 引用 (Scopus)

Situation of monomethoxypolyethylene glycol covalently attached to lysozyme

So, T., Ueda, T., Abe, Y., Nakamata, T. & Imoto, T., 1 1 1996, : : Journal of Biochemistry. 119, 6, p. 1086-1093 8 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Magnetic Resonance Spectroscopy
Nuclear magnetic resonance
Immunoglobulin Fab Fragments
monomethoxypolyethylene glycol
19 引用 (Scopus)

Stabilization of lysozyme by introducing N-glycosylation signal sequence

Ueda, T., Iwashita, H., Hashimoto, Y. & Imoto, T., 1 1 1996, : : Journal of Biochemistry. 119, 1, p. 157-161 5 p.

研究成果: ジャーナルへの寄稿記事

Glycosylation
Muramidase
Protein Sorting Signals
Stabilization
Oligosaccharides
19 引用 (Scopus)

The nucleoid protein H-NS facilitates chromosome DNA replication in Escherichia coli dnaA mutants

Katayama, T., Takata, M. & Sekimizu, K., 1 1 1996, : : Journal of bacteriology. 178, 19, p. 5790-5792 3 p.

研究成果: ジャーナルへの寄稿記事

DNA Replication
Chromosomes
Escherichia coli
Thymine
Proteins
14 引用 (Scopus)

The possible role of nitric oxide in relaxations and excitatory neuroeffector transmission in the cat airway

Tanaka, H., Jing, L., Takahashi, S. & Ito, Y., 6 15 1996, : : Journal of Physiology. 493, 3, p. 785-791 7 p.

研究成果: ジャーナルへの寄稿記事

Nitric Oxide
Cats
NG-Nitroarginine Methyl Ester
Electric Stimulation
Bronchi
1995
18 引用 (Scopus)

Aplyparvunin, a bioactive acetogenin from the sea hare Aplysia parvula

Miyamoto, T., Ebisawa, Y. & Higuchi, R., 8 21 1995, : : Tetrahedron Letters. 36, 34, p. 6073-6074 2 p.

研究成果: ジャーナルへの寄稿記事

Acetogenins
Hares
Aplysia
Mollusca
Military Personnel
18 引用 (Scopus)

Bioactive diterpenoids from octocorallia, 2. deoxyxeniolide B, a novel ichthyotoxic diterpenoid from the soft coral xenia elongata

Miyamoto, T., Takenaka, Y., Yamada, K. & Higuchi, R., 6 1995, : : Journal of Natural Products. 58, 6, p. 924-928 5 p.

研究成果: ジャーナルへの寄稿記事

Anthozoa
Diterpenes
Spectrum analysis
Oxidation
deoxyxeniolide B
4 引用 (Scopus)

Biochemical characterization of liver microsomal, golgi, lysosomal, and serum β-glucuronidases in dibuty1 phosphate-treated rats

Nishimura, Y., Kato, K. & Himeno, M., 1 1 1995, : : Journal of biochemistry. 118, 1, p. 56-66 11 p.

研究成果: ジャーナルへの寄稿記事

Glucuronidase
Liver
Rats
Phosphates
Serum
6 引用 (Scopus)

Biochemical Properties and Intracellular Processing of Lysosomal Cathepsins B and H

Nishimura, Y., Tsuji, H., Kato, K., Sato, H., Amano, J., Himeno, M. & Tsuji, H., 1 1 1995, : : Biological and Pharmaceutical Bulletin. 18, 6, p. 829-836 8 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Cathepsin B
Radioactivity
yeast proteinase B
Lysosomes
2 引用 (Scopus)

Biosynthesis, processing, and lysosome targeting of acid phosphatase

Himeno, M. & Tanaka, Y., 1 1 1995, : : Nippon rinsho. Japanese journal of clinical medicine. 53, 12, p. 2898-2903 6 p.

研究成果: ジャーナルへの寄稿評論記事

Acid Phosphatase
Lysosomes
Membranes
Liver
Enzymes
8 引用 (Scopus)

Biosynthesis and Processing of Lysosomal Cathepsin D in Primary Cultures of Rat Hepatocytes

Nishimura, Y., Kato, K., Himeno, M. & Koji, F., 1 1 1995, : : Biological and Pharmaceutical Bulletin. 18, 6, p. 825-828 4 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
Enzyme Precursors
Hepatocytes
Tunicamycin
Chloroquine
19 引用 (Scopus)

Cannabinerolic acid, a cannabinoid from Cannabis sativa

Taura, F., Morimoto, S. & Shoyama, Y., 1 1 1995, : : Phytochemistry. 39, 2, p. 457-458 2 p.

研究成果: ジャーナルへの寄稿記事

cannabinoids
Cannabis sativa
Cannabinoids
Cannabis
Acids
5 引用 (Scopus)

Cathepsin D associates with lysosomal membranous protein

Nishimura, Y. & Himeno, M., 1 1 1995, : : Biological and Pharmaceutical Bulletin. 18, 10, p. 1340-1346 7 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
Membranes
Lysosome-Associated Membrane Glycoproteins
IGF Type 2 Receptor
lysosomal proteins
18 引用 (Scopus)

Characterization of Escherichia coli DnaAcos protein in replication systems reconstituted with highly purified proteins

Katayama, T., Crooke, E. & Sekimizu, K., 1 1 1995, : : Molecular Microbiology. 18, 5, p. 813-820 8 p.

研究成果: ジャーナルへの寄稿記事

Escherichia coli Proteins
Proteins
Single-Stranded DNA
DnaB Helicases
Nucleotides
4 引用 (Scopus)

Correlation between the differences in the free energy change and conformational energy in the folded state of hen lysozymes with gly-pro and pro-gly sequences introduced to the same site

Motoshima, H., Ueda, T., Hashimoto, Y., Tsutsumi, M. & Imoto, T., 1 1 1995, : : Journal of Biochemistry. 118, 6, p. 1138-1144 7 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Free energy
prolylglycine
glycylproline
poly(prolylprolylglycine)15
71 引用 (Scopus)

Effective renaturation of reduced lysozyme by gentle removal of urea

Maeda, Y., Koga, H., Yamada, H., Ueda, T. & Imoto, T., 2 1 1995, : : Protein Engineering, Design and Selection. 8, 2, p. 201-205 5 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Urea
Enzymes
Dialysis
Buffers
6 引用 (Scopus)

Effect of a coplanar PCB on lipid metabolism: the remarkable difference between rats and guinea pigs

Hatsumura, M., Ishida, T., Ishii, Y., Ariyoshi, N., Oguri, K. & Yoshimura, H., 1 1 1995, : : Fukuoka igaku zasshi = Hukuoka acta medica. 86, 5, p. 135-143 9 p.

研究成果: ジャーナルへの寄稿記事

Polychlorinated Biphenyls
Lipid Metabolism
Guinea Pigs
Control Groups
Triglycerides
38 引用 (Scopus)

Effect of salt concentration on the pKa of acidic residues in lysozyme

Abe, Y., Ueda, T., Iwashita, H., Hashimoto, Y., Motoshima, H., Tanaka, Y. & Imoto, T., 10 1 1995, : : Journal of biochemistry. 118, 5, p. 946-952 7 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Salts
Nuclear magnetic resonance
Protein Denaturation
Biochemistry

Expression of rat cathepsin D cDNA in Saccharomyces cerevisiae: Intracellular sorting of cathepsin D to yeast vacuole

Nishimura, Y., Fujita, H., Kato, K. & Himeno, M., 1 1 1995, : : Advances in experimental medicine and biology. 362, p. 289-292 4 p.

研究成果: ジャーナルへの寄稿記事

Tunicamycin
Cathepsin D
Molecular Cloning
Vacuoles
Sorting
8 引用 (Scopus)

Expression of rat cathepsin D cDNA in Saccharomyces cerevisiae: Implications for intracellular targeting of cathepsin D to vacuoles

Nishimura, Y., Takeshima, H., Sakaguchi, M., Mihara, K., Omura, T., Kato, K. & Himeno, M., 7 1995, : : Journal of biochemistry. 118, 1, p. 168-177 10 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
Vacuoles
Yeast
Saccharomyces cerevisiae
Rats
88 引用 (Scopus)

First Direct Evidence for the Mechanism of Δ1-Tetrahydrocannabinolie Acid Biosynthesis

Taura, F., Morimoto, S., Shoyama, Y. & Mechoulam, R., 1 1 1995, : : Journal of the American Chemical Society. 117, 38, p. 9766-9767 2 p.

研究成果: ジャーナルへの寄稿記事

Biosynthesis
Acids
3 引用 (Scopus)

Inhibitory Effect of Ethanol and Colchicine on the Intracellular Processing of β-Glucuronidase Which Occurs in the Golgi Complex

Nishimura, Y., Kato, K., Himeno, M. & Oda, K., 1 1 1995, : : Biological and Pharmaceutical Bulletin. 18, 7, p. 938-944 7 p.

研究成果: ジャーナルへの寄稿記事

Glucuronidase
Colchicine
Golgi Apparatus
Ethanol
Enzymes
12 引用 (Scopus)

Inhibitory Effect of Leupeptin on the Intracellular Maturation of Lysosomal Cathepsin L in Primary Cultures of Rat Hepatocytes

Nishimura, Y., Kato, K., Himeno, M. & Furuno, K., 1 1 1995, : : Biological and Pharmaceutical Bulletin. 18, 7, p. 945-950 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
Enzyme Precursors
Hepatocytes
Molecular Weight
Cysteine Proteinase Inhibitors
4 引用 (Scopus)

Intracellular sorting of lysosomal β-glucuronidase is altered due to administaration of dibutyl phosphate

Nishimura, Y., Kato, K., Oda, K., Ishikawa, T., Ikehara, Y. & Himeno, M., 1 1 1995, : : Journal of biochemistry. 118, 1, p. 46-55 10 p.

研究成果: ジャーナルへの寄稿記事

Glucuronidase
Sorting
Rats
Enzymes
Serum
12 引用 (Scopus)

Intracellular targeting of lysosomal cathepsin D in COS cells

Takeshima, H., Sakaguchi, M., Mihara, K., Murakami, K., Omura, T., Himeno, M. & Nishimura, Y., 10 1 1995, : : Journal of biochemistry. 118, 5, p. 981-988 8 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
COS Cells
Mutant Proteins
Sorting
Endoplasmic Reticulum

Isolation and characterization of inhibitory factors of DNA polymerase III holoenzyme from Escherichia coli

Hase, M., Mizushima, T., Katayama, T. & Sekimizu, K., 8 1 1995, : : FEMS microbiology letters. 130, 2-3, p. 215-220 6 p.

研究成果: ジャーナルへの寄稿記事

DNA Polymerase III
DNA Polymerase I
Holoenzymes
DNA-Directed DNA Polymerase
Escherichia coli
10 引用 (Scopus)

Kinetically Trapped Structure in the Renaturation of Reduced Oxindolealanine 62 Lysozyme

Ueda, T., Abe, Y., Ohkuri, T., Kawano, K., Terada, Y. & Imoto, T., 12 1995, : : Biochemistry. 34, 49, p. 16178-16185 8 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Derivatives
Denaturation
Interchanges
Chromatography
28 引用 (Scopus)

Purification and characterization of a newly identified isoform of cytochrome P450 responsible for 3-hydroxylation of 2, 5, 2', 5'-tetrachlorobiphenyl in hamster liver

Koga, N., Kikuichi-Nishimura, N., Hara, T., Harada, N., Ishii, Y., Yamada, H., Oguri, K. & Yoshimura, H., 3 10 1995, : : Archives of Biochemistry and Biophysics. 317, 2, p. 464-470 7 p.

研究成果: ジャーナルへの寄稿記事

Hydroxylation
Cricetinae
Liver
Cytochrome P-450 Enzyme System
Purification
22 引用 (Scopus)

Purification and characterization of flavone-specific β-glucuronidase from callus cultures of Scutellaria baicalensis Georgi

Morimoto, S., Harioka, T. & Shoyama, Y., 2 1 1995, : : Planta. 195, 4, p. 535-540 6 p.

研究成果: ジャーナルへの寄稿記事

flavone
Scutellaria baicalensis
Glucuronidase
Bony Callus
callus culture
9 引用 (Scopus)

Structure determination of the major component of the starfish ganglioside molecular species LG-2 by tandem mass spectrometry

Higuchi, R., Matsumoto, S., Isobe, R. & Miyamoto, T., 8 14 1995, : : Tetrahedron. 51, 33, p. 8961-8968 8 p.

研究成果: ジャーナルへの寄稿記事

Starfish
Gangliosides
Tandem Mass Spectrometry
Mass spectrometry
Positive ions
1994
48 引用 (Scopus)

Bioactive terpenoids from Octocorallia, I. Bioactive diterpenoids: Litophynols A and B from the mucus of the soft coral Litophyton sp.

Miyamoto, T., Yamada, K., Ikeda, N., Komori, T. & Higuchi, R., 9 1 1994, : : Journal of Natural Products. 57, 9, p. 1212-1219 8 p.

研究成果: ジャーナルへの寄稿記事

Anthozoa
Diterpenes
Terpenes
Mucus
X-Rays
32 引用 (Scopus)

Constituents of holothuroideae, IV. Isolation and structure of three new cerebrosides, CE‐2b, CE‐2c and CE‐2d, from the sea cucumber Cucumaria echinata

Higuchi, R., Inagaki, M., Togawa, K., Miyamoto, T. & Komori, T., 1 1 1994, : : Liebigs Annalen der Chemie. 1994, 1, p. 79-81 3 p.

研究成果: ジャーナルへの寄稿記事

Cucumaria
Sea Cucumbers
Cerebrosides
Glucosylceramides
Liquid Chromatography
59 引用 (Scopus)

Constituents of Holothuroideae, V. Isolation and Structure of Cerebrosides from the Sea Cucumber Pentacta australis

Higuchi, R., Inagaki, M., Togawa, K., Miyamoto, T. & Komori, T., 1 1 1994, : : Liebigs Annalen der Chemie. 1994, 7, p. 653-658 6 p.

研究成果: ジャーナルへの寄稿記事

Sea Cucumbers
Cerebrosides
Cucumaria
Glucosylceramides
Methanol
41 引用 (Scopus)

Determination of tetrahydrocannabinolic acid—carrier protein conjugate by matrix‐assisted laser desorption/ionization mass spectrometry and antibody formation

Goto, Y., Shima, Y., Morimoto, S., Shoyama, Y., Murakami, H., Kusai, A. & Nojima, K., 1 1 1994, : : Organic Mass Spectrometry. 29, 11, p. 668-671 4 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal antibodies
Antigens
Bovine Serum Albumin
antibodies
albumins

Effect of coplanar PCB on gluconeogenesis and lipid metabolism: Comparison between rats and guinea pigs

Hatsumura, M., Ishida, T., Ishii, Y., Ariyoshi, N., Koga, Y., Oguri, K. & Yoshimura, H., 1 1 1994, : : Japanese Journal of Toxicology and Environmental Health. 40, 1

研究成果: ジャーナルへの寄稿記事

Gluconeogenesis
Polychlorinated Biphenyls
Lipid Metabolism
Guinea Pigs
12 引用 (Scopus)

Formation of α-helix 88-98 is essential in the establishment of higher-order structure from reduced lysozyme

Ueda, T., Nakashima, A., Hashimoto, Y., Miki, T., Yamada, H. & Imoto, T., 1 27 1994, : : Journal of Molecular Biology. 235, 4, p. 1312-1317 6 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Peptide Fragments
Basic Amino Acids
56 引用 (Scopus)
Escherichia coli Proteins
Mutant Proteins
Escherichia coli
Proteins
Plasmids
14 引用 (Scopus)

Immunocytochemical localization of cathepsin L in the synovial lining cells of the rat temporomandibular joint

Kiyoshima, T., Kido, M. A., Nishimura, Y., Himeno, M., Tsukuba, T., Tashiro, H., Yamamoto, K. & Tanaka, T., 1 1 1994, : : Archives of Oral Biology. 39, 12, p. 1049-1056 8 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
Temporomandibular Joint
Vacuoles
Lysosomes
Fibroblasts
10 引用 (Scopus)

Induction of bilirubin UDP-glucuronyltransferase and CYP4A1 P450 by co-planar PCBs: Different responsiveness of guinea pigs and rats

Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H., Oguri, K., Funae, Y. & Yoshimura, H., 2 1994, : : Chemosphere. 28, 3, p. 639-645 7 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Polychlorinated Biphenyls
Polychlorinated biphenyls
pig
Rats
41 引用 (Scopus)

Isolation and Characterization of 101-Succinimide Lysozyme That Possesses the Cyclic Imide at Asp101-Gly102

Tomizawa, H., Ueda, T., Imoto, T. & Yamada, H., 7 1 1994, : : Biochemistry. 33, 29, p. 8770-8774 5 p.

研究成果: ジャーナルへの寄稿記事

Imides
Muramidase
succinimide
Cations
Hydrolysis
77 引用 (Scopus)

Localization of cathepsins B, D, and L in the rat osteoclast by immuno-light and -electron microscopy

Goto, T., Tanaka, T., Kiyoshima, T., Moroi, R., Tsukuba, T., Yamamoto, K., Nishimura, Y. & Himeno, M., 1 1 1994, : : Histochemistry. 101, 1, p. 33-40 8 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
cathepsin B
Cathepsin B
Cathepsin D
osteoclasts
50 引用 (Scopus)

Post-harvest degradation of carotenoid glucose esters in saffron

Morimoto, S., Umezaki, Y., Shoyama, Y., Saito, H., Nishi, K. & Irino, N., 10 31 1994, : : Planta medica. 60, 5, p. 438-440 3 p.

研究成果: ジャーナルへの寄稿記事

Carotenoids
Esters
Glucosidases
Glucose
Degradation
49 引用 (Scopus)

Production of lithospermic acid B and rosmarinic acid in callus tissue and regenerated plantlets of salvia miltiorrhiza

Morimoto, S., Goto, Y. & Shoyama, Y., 6 1 1994, : : Journal of Natural Products. 57, 6, p. 817-823 7 p.

研究成果: ジャーナルへの寄稿記事

N-benzyladenine
Salvia miltiorrhiza
Bony Callus
Tissue
Kinetin
13 引用 (Scopus)

Purification and characterization of dog liver microsomal epoxide hydrolase

Ariyoshi, N., Tanaka, M., Ishii, Y. & Oguri, K., 1 1 1994, : : Journal of biochemistry. 115, 5, p. 985-990 6 p.

研究成果: ジャーナルへの寄稿記事

Epoxide Hydrolases
Liver
Purification
Dogs
Enzymes
20 引用 (Scopus)

Purification of a Phenobarbital-Inducible Morphine UDP-Glucuronosyltransferase Isoform, Absent from Gunn Rat Liver

Ishii, Y., Tsuruda, K., Tanaka, M. & Oguri, K., 12 1 1994, : : Archives of Biochemistry and Biophysics. 315, 2, p. 345-351 7 p.

研究成果: ジャーナルへの寄稿記事

Gunn Rats
Glucuronosyltransferase
Phenobarbital
Liver
Morphine
5 引用 (Scopus)

Reduction of disulfide bonds in proteins by 2-aminothiophenol under weakly acidic conditions

Abe, Y., Ueda, T. & Imoto, T., 1994, : : Journal of Biochemistry. 115, 1, p. 52-67 16 p.

研究成果: ジャーナルへの寄稿記事

Pancreatic Ribonuclease
Muramidase
Disulfides
Egg White
Trypsin Inhibitors
8 引用 (Scopus)
Strychnine
Glucuronosyltransferase
Phenobarbital
Cytochrome P-450 Enzyme System
Hydroxylation
21 引用 (Scopus)

The role of net charge on the renaturation of reduced lysozyme by the sulfhydryl-disulfide interchange reaction

Maeda, Y., Ueda, T., Yamada, H. & Imoto, T., 10 1 1994, : : Protein Engineering, Design and Selection. 7, 10, p. 1249-1254 6 p.

研究成果: ジャーナルへの寄稿記事

Interchanges
Muramidase
Disulfides
Enzymes
Agglomeration
22 引用 (Scopus)

Triterpenoids from callus tissue of Actinidia polygama

Sashida, Y., Ogawa, K., Yamanouchi, T., Tanaka, H., Shoyama, Y. & Nishioka, I., 1 1994, : : Phytochemistry. 35, 2, p. 377-380 4 p.

研究成果: ジャーナルへの寄稿記事

Actinidia polygama
Actinidia
Bony Callus
triterpenoids
callus
1993
14 引用 (Scopus)

Cannabis, 21. Biotransformation of cannabinol to its glycosides by in vitro plant tissue

Tanaka, H., Morimoto, S. & Shoyama, Y., 12 1993, : : Journal of Natural Products. 56, 12, p. 2068-2072 5 p.

研究成果: ジャーナルへの寄稿記事

Cannabinol
Cannabis
Glycosides
Biotransformation
Metabolites