研究成果 1976 2019

1994
10 引用 (Scopus)

Induction of bilirubin UDP-glucuronyltransferase and CYP4A1 P450 by co-planar PCBs: Different responsiveness of guinea pigs and rats

Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H., Oguri, K., Funae, Y. & Yoshimura, H., 2 1994, : : Chemosphere. 28, 3, p. 639-645 7 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Polychlorinated Biphenyls
Polychlorinated biphenyls
pig
Rats
41 引用 (Scopus)

Isolation and Characterization of 101-Succinimide Lysozyme That Possesses the Cyclic Imide at Asp101-Gly102

Tomizawa, H., Ueda, T., Imoto, T. & Yamada, H., 7 1 1994, : : Biochemistry. 33, 29, p. 8770-8774 5 p.

研究成果: ジャーナルへの寄稿記事

Imides
Muramidase
succinimide
Cations
Hydrolysis
77 引用 (Scopus)

Localization of cathepsins B, D, and L in the rat osteoclast by immuno-light and -electron microscopy

Goto, T., Tanaka, T., Kiyoshima, T., Moroi, R., Tsukuba, T., Yamamoto, K., Nishimura, Y. & Himeno, M., 1 1 1994, : : Histochemistry. 101, 1, p. 33-40 8 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
cathepsin B
Cathepsin B
Cathepsin D
osteoclasts
50 引用 (Scopus)

Post-harvest degradation of carotenoid glucose esters in saffron

Morimoto, S., Umezaki, Y., Shoyama, Y., Saito, H., Nishi, K. & Irino, N., 10 31 1994, : : Planta medica. 60, 5, p. 438-440 3 p.

研究成果: ジャーナルへの寄稿記事

Carotenoids
Esters
Glucosidases
Glucose
Degradation
49 引用 (Scopus)

Production of lithospermic acid B and rosmarinic acid in callus tissue and regenerated plantlets of salvia miltiorrhiza

Morimoto, S., Goto, Y. & Shoyama, Y., 6 1 1994, : : Journal of Natural Products. 57, 6, p. 817-823 7 p.

研究成果: ジャーナルへの寄稿記事

N-benzyladenine
Salvia miltiorrhiza
Bony Callus
Tissue
Kinetin
13 引用 (Scopus)

Purification and characterization of dog liver microsomal epoxide hydrolase

Ariyoshi, N., Tanaka, M., Ishii, Y. & Oguri, K., 1 1 1994, : : Journal of biochemistry. 115, 5, p. 985-990 6 p.

研究成果: ジャーナルへの寄稿記事

Epoxide Hydrolases
Liver
Purification
Dogs
Enzymes
20 引用 (Scopus)

Purification of a Phenobarbital-Inducible Morphine UDP-Glucuronosyltransferase Isoform, Absent from Gunn Rat Liver

Ishii, Y., Tsuruda, K., Tanaka, M. & Oguri, K., 12 1 1994, : : Archives of Biochemistry and Biophysics. 315, 2, p. 345-351 7 p.

研究成果: ジャーナルへの寄稿記事

Gunn Rats
Glucuronosyltransferase
Phenobarbital
Liver
Morphine
5 引用 (Scopus)

Reduction of disulfide bonds in proteins by 2-aminothiophenol under weakly acidic conditions

Abe, Y., Ueda, T. & Imoto, T., 1994, : : Journal of Biochemistry. 115, 1, p. 52-67 16 p.

研究成果: ジャーナルへの寄稿記事

Pancreatic Ribonuclease
Muramidase
Disulfides
Egg White
Trypsin Inhibitors
8 引用 (Scopus)
Strychnine
Glucuronosyltransferase
Phenobarbital
Cytochrome P-450 Enzyme System
Hydroxylation
21 引用 (Scopus)

The role of net charge on the renaturation of reduced lysozyme by the sulfhydryl-disulfide interchange reaction

Maeda, Y., Ueda, T., Yamada, H. & Imoto, T., 10 1 1994, : : Protein Engineering, Design and Selection. 7, 10, p. 1249-1254 6 p.

研究成果: ジャーナルへの寄稿記事

Interchanges
Muramidase
Disulfides
Enzymes
Agglomeration
22 引用 (Scopus)

Triterpenoids from callus tissue of Actinidia polygama

Sashida, Y., Ogawa, K., Yamanouchi, T., Tanaka, H., Shoyama, Y. & Nishioka, I., 1 1994, : : Phytochemistry. 35, 2, p. 377-380 4 p.

研究成果: ジャーナルへの寄稿記事

Actinidia polygama
Actinidia
Bony Callus
triterpenoids
callus
1993
14 引用 (Scopus)

Cannabis, 21. Biotransformation of cannabinol to its glycosides by in vitro plant tissue

Tanaka, H., Morimoto, S. & Shoyama, Y., 12 1993, : : Journal of Natural Products. 56, 12, p. 2068-2072 5 p.

研究成果: ジャーナルへの寄稿記事

Cannabinol
Cannabis
Glycosides
Biotransformation
Metabolites

Expression and Localization of a Major Lysosomal Membrane Sialoglycoprotein (LGP107) in Plasma Membranes of Rat Osteoblasts and Osteocytes

Akamine, A., Klmura, R., Maeda, K., Tsukuba, T., Yamamoto, K., Tanaka, Y. & Kato, K., 1 1 1993, : : Archives of Histology and Cytology. 56, 5, p. 525-532 8 p.

研究成果: ジャーナルへの寄稿記事

Sialoglycoproteins
Osteocytes
Osteoblasts
Cell Membrane
Membranes
68 引用 (Scopus)

Immunohistochemical localization of cathepsins B, D and L in the rat osteoclast

Goto, T., Tsukuba, T., Kiyoshima, T., Nishimura, Y., Kato, K., Yamamoto, K. & Tanaka, T., 5 1 1993, : : Histochemistry. 99, 5, p. 411-414 4 p.

研究成果: ジャーナルへの寄稿記事

cathepsin L
Cathepsin L
cathepsin B
Cathepsin B
Cathepsin D
8 引用 (Scopus)

Increased synthesis and specific localization of a major lysosomal membrane sialoglycoprotein (LGP107) at the ruffled border membrane of active osteoclasts

Akamine, A., Tsukuba, T., Kimura, R., Maeda, K., Tanaka, Y., Kato, K. & Yamamoto, K., 8 1 1993, : : Histochemistry. 100, 2, p. 101-108 8 p.

研究成果: ジャーナルへの寄稿記事

Sialoglycoproteins
osteoclasts
Osteoclasts
synthesis
Membranes
4 引用 (Scopus)

Inducing ability of co-planar PCBs toward bilirubin UDP-glucuronyltransferase of liver microsomes: the remarkable difference between guinea pigs and rats

Oguri, K., Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H. & Yoshimura, H., 1 1 1993, : : Fukuoka igaku zasshi = Hukuoka acta medica. 84, 5, p. 175-180 6 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Polychlorinated Biphenyls
Liver Microsomes
Guinea Pigs
Methylcholanthrene

Induction of Bilirubin UDP-Glucuronyltransferase and P-450 4A Subfamily in Guinea Pigs

Koga, Y., Funaec, Y., Yoshimura, H., Ariyoshi, N., Ishii, Y., Yamada, H., Oguri, K. & Tsuda, M., 1 1 1993, : : Eisei kagaku. 39, 1

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Guinea Pigs

Induction of bilirubin UDP-glucuronyltransferase and P-450 4A subfamily in guinea pigs by treatment with coplanar PCB

Koga, Y., Tsuda, M., Ariyoshi, N., Ishii, Y., Yamada, H., Oguri, K., Yoshimura, H. & Funae, Y., 1993, : : Japanese Journal of Toxicology and Environmental Health. 39, 1

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Polychlorinated Biphenyls
Guinea Pigs
11 引用 (Scopus)

Modification of the gluconeogenesis is not involved in the co-planar PCB toxicity in highly sensitive guinea pigs

Oguri, K., Hatsumura, M., Ishii, Y., Koga, Y., Ariyoshi, N. & Yoshimura, H., 12 1993, : : Chemosphere. 27, 11, p. 2295-2303 9 p.

研究成果: ジャーナルへの寄稿記事

Gluconeogenesis
Polychlorinated Biphenyls
Polychlorinated biphenyls
pig
Toxicity
22 引用 (Scopus)

Picrotoxin as a potent inducer of rat hepatic cytochrome P450, CYP2b1 and CYP2b2

Yamada, H., Fujisaki, H., Kaneko, H., Ishii, Y., Hamaguchi, T. & Oguri, K., 5 5 1993, : : Biochemical Pharmacology. 45, 9, p. 1783-1789 7 p.

研究成果: ジャーナルへの寄稿記事

Picrotoxin
Cytochrome P-450 Enzyme System
Rats
Hydroxylation
Liver
11 引用 (Scopus)

Purification and Characterization of a Morphine UDP-Glucuronyltransferase Isoform from Untreated Rat Liver

Ishii, Y., Oguri, K. & Yoshimura, H., 1 1 1993, : : Biological and Pharmaceutical Bulletin. 16, 8, p. 754-758 5 p.

研究成果: ジャーナルへの寄稿記事

Glucuronosyltransferase
Uridine Diphosphate
Sepharose
Morphine
Protein Isoforms
24 引用 (Scopus)

Purification and processing of rat liver procathepsin B

Kawabata, T., Nishimura, Y., Higaki, M. & Kato, K., 1 1 1993, : : Journal of Biochemistry. 113, 3, p. 389-394 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin B
Enzyme Precursors
Liver
Purification
Rats
35 引用 (Scopus)

Stabilization of lysozyme by the introduction of gly-pro sequence

Ueda, T., Tamura, T., Maeda, Y., Hashimoto, Y., Miki, T., Yamada, H. & Imoto, T., 2 1 1993, : : Protein Engineering, Design and Selection. 6, 2, p. 183-187 5 p.

研究成果: ジャーナルへの寄稿記事

glycylproline
Muramidase
Enzymes
Stabilization
Proline
36 引用 (Scopus)

The primary structures and properties of non‐stomach lysozymes of sheep and cow, and implication for functional divergence of lysozyme

ITO, Y., YAMADA, H., NAKAMURA, M., YOSHIKAWA, A., Ueda, T. & IMOTO, T., 1 1 1993, : : European Journal of Biochemistry. 213, 2, p. 649-658 10 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Sheep
Kidney
Stomach
Ruminant Stomach
14 引用 (Scopus)
Protein Unfolding
Thermodynamics
Derivatives
Kinetics
Digestion
1992
35 引用 (Scopus)

Endo- and Aminopeptidase Activities of Rat Cathepsin H

Koga, H., Mori, N., Yamada, H., Nishimura, Y., Tokuda, K., Kato, K. & Taiji, T., 1 1 1992, : : Chemical and Pharmaceutical Bulletin. 40, 4, p. 965-970 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Endopeptidases
Aminopeptidases
Rats
Peptides
11 引用 (Scopus)

Expression of mouse cathepsin L cDNA in Saccharomyces cerevisiae: Evidence that cathepsin L is sorted for targeting to yeast vacuole

Nishimura, Y. & Kato, K., 11 1 1992, : : Archives of Biochemistry and Biophysics. 298, 2, p. 318-324 7 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
Vacuoles
Yeast
Saccharomyces cerevisiae
Complementary DNA
47 引用 (Scopus)

Flavan-3-ol gallates and proanthocyanidins from Pithecellobium lobatum

Min-Won, L., Morimoto, S., Nonaka, G. I. & Nishioka, I., 1 1 1992, : : Phytochemistry. 31, 6, p. 2117-2120 4 p.

研究成果: ジャーナルへの寄稿記事

Archidendron jiringa
Proanthocyanidins
epigallocatechin
proanthocyanidins
Fabaceae
26 引用 (Scopus)

Isolation and sequencing of a cDNA clone encoding the 85 kDa human lysosomal sialoglycoprotein (hLGP85) in human metastatic pancreas islet tumor cells

Fujita, H., Takata, Y., Kono, A., Tanaka, Y., Takahashi, T., Himeno, M. & Kato, K., 4 30 1992, : : Biochemical and Biophysical Research Communications. 184, 2, p. 604-611 8 p.

研究成果: ジャーナルへの寄稿記事

Sialoglycoproteins
Islet Cell Adenoma
Rats
Tumors
Pancreas
1 引用 (Scopus)

Possible involvement of cathepsin L in processing of rat liver hexokinase to eliminate mitochondria-binding ability

Okazaki, H., Tanl, C., Ando, M., Ishii, K., Ishibashi, S., Nishimura, Y. & Kato, K., 1 1 1992, : : Journal of biochemistry. 112, 3, p. 409-413 5 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
Mitochondria
Hexokinase
Liver
Rats
31 引用 (Scopus)

Structures of four new triterpenoid oligoglycosides: DS-penaustrosides A, B, C, and D from the sea cucumber pentacta australis

Miyamoto, T., Togawa, K., Higuchi, R., Komori, T. & Sasaki, T., 7 1 1992, : : Journal of Natural Products. 55, 7, p. 940-946 7 p.

研究成果: ジャーナルへの寄稿記事

Sea Cucumbers
Glycosides
19 引用 (Scopus)

Three new cytotoxic sesterterpenoids, inorolide A, B, and C from the nudibranch Chromodoris inornata

Miyamoto, T., Sakamoto, K., Amano, H., Higuchi, R., Komori, T. & Sasaki, T., 9 22 1992, : : Tetrahedron Letters. 33, 39, p. 5811-5814 4 p.

研究成果: ジャーナルへの寄稿記事

X-Rays
Single crystals
X rays
1991
3 引用 (Scopus)

1H-NMR study of the intramolecular interaction of a substrate analogue covalently attached to aspartic acid-101 in lysozyme

Ueda, T., Isakari, Y., Aoki, H., Yasukochi, T., Masutomo, S. I., Kawano, K., Terada, Y., Yamada, H. & Imoto, T., 1 1 1991, : : Journal of Biochemistry. 109, 5, p. 690-698 9 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Aspartic Acid
Nuclear magnetic resonance
Catalytic Domain
Substrates
41 引用 (Scopus)

Bafilomycin A1 inhibits the targeting of lysosomal acid hydrolases in cultured hepatocytes

Oda, K., Nishimura, Y., Ikehara, Y. & Kato, K., 7 15 1991, : : Biochemical and Biophysical Research Communications. 178, 1, p. 369-377 9 p.

研究成果: ジャーナルへの寄稿記事

Hydrolases
Hepatocytes
Acids
Cathepsin H
Vacuolar Proton-Translocating ATPases
35 引用 (Scopus)

Isolation and sequencing of a cDNA clone encoding rat liver lysosomal cathepsin D and the structure of three forms of mature enzymes

Fujita, H., Tanaka, Y., Noguchi, Y., Kono, A., Himeno, M. & Kato, K., 8 30 1991, : : Biochemical and Biophysical Research Communications. 179, 1, p. 190-196 7 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
Liver
Rats
Complementary DNA
Clone Cells
4 引用 (Scopus)

Mechanisms of a conversion from membrane associated lysosomal acid phosphatase to content forms

Himeno, M., Nakamura, K., Tanaka, Y., Yamada, H., Imoto, T. & Kato, K., 11 14 1991, : : Biochemical and Biophysical Research Communications. 180, 3, p. 1483-1489 7 p.

研究成果: ジャーナルへの寄稿記事

Acid Phosphatase
Cathepsin D
Membranes
Enzymes
Lysosomes
35 引用 (Scopus)

Multiple proteolytic action of rat liver cathepsin B: Specificities and pH-dependences of the endo- and exopeptidase activities

Koga, H., Yamada, H., Nishimura, Y., Kato, K. & Imoto, T., 1 1 1991, : : Journal of Biochemistry. 110, 2, p. 179-188 10 p.

研究成果: ジャーナルへの寄稿記事

Exopeptidases
Endopeptidases
Cathepsin B
Carboxypeptidases
Liver
19 引用 (Scopus)

Preparation and properties of a lysozyme derivative in which two domains are cross-linked intramolecularly between trp62 and asp101

Ueda, T., Yamada, H., Sakamoto, N., Abe, Y., Kawano, K., Terada, Y. & Imoto, T., 1 1 1991, : : Journal of biochemistry. 110, 5, p. 719-725 7 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Derivatives
Chromatography
Carbodiimides
Micrococcus
4 引用 (Scopus)

Rat cathepsin H-catalyzed transacylation: Comparisons of the mechanism and the specificity with papain-superfamily proteases

Koga, H., Mori, N., Yamada, H., Nishimura, Y., Tokuda, K., Kato, K. & Imoto, T., 1 1 1991, : : Journal of Biochemistry. 110, 6, p. 939-944 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Papain
Amides
Rats
Peptide Hydrolases
1990
23 引用 (Scopus)

Augmented excretion of procathepsin L of a fos-transferred highly metastatic rat cell line

Taniguchi, S., Nishimura, Y., Takahashi, T., Baba, T. & Kato, K., 4 30 1990, : : Biochemical and Biophysical Research Communications. 168, 2, p. 520-526 7 p.

研究成果: ジャーナルへの寄稿記事

Rats
Cells
4 alpha-glucanotransferase
Cell Line
fos Genes
22 引用 (Scopus)

Biosythesis processing, and intracellular transport of lysosomal acid phosphatase in rat hepatocytes

Tanaka, Y., Harada, R., Himeno, M. & Kato, K., 1 1 1990, : : Journal of biochemistry. 108, 2, p. 278-286 9 p.

研究成果: ジャーナルへの寄稿記事

Acid Phosphatase
Rats
Hepatocytes
Lysosomes
Processing
103 引用 (Scopus)

Characterization of a mutation in a family with saposin B deficiency: a glycosylation site defect

Kretz, K. A., Carson, G. S., Morimoto, S., Kishimoto, Y., Fluharty, A. L. & O'Brien, J. S., 4 1990, : : Proceedings of the National Academy of Sciences of the United States of America. 87, 7, p. 2541-4 4 p.

研究成果: ジャーナルへの寄稿記事

Saposins
Glycosylation
Mutation
Metachromatic Leukodystrophy
Isoleucine
26 引用 (Scopus)

Comparative study on specificities of rat cathepsin L and papain: Amino acid differences at substrate-binding sites are involved in their specificities

Koga, H., Yamada, H., Nishimura, Y., Kato, K. & Imoto, T., 1 1 1990, : : Journal of Biochemistry. 108, 6, p. 976-982 7 p.

研究成果: ジャーナルへの寄稿記事

Papain
Cathepsin L
Binding Sites
Amino Acids
Substrates
7 引用 (Scopus)
glucosides
Glycosides
isolation
44 引用 (Scopus)

Constituents of holothuroidea, II. Six newly identified biologically active triterpenoid glycoside sulfates from the sea cucumber Cucumaria echinata

Miyamoto, T., Togawa, K., Higuchi, R., Komori, T. & Sasaki, T., 1 1 1990, : : Liebigs Annalen der Chemie. 1990, 5, p. 453-460 8 p.

研究成果: ジャーナルへの寄稿記事

Cucumaria
Sea Cucumbers
KB Cells
Glycosides
Sulfates
13 引用 (Scopus)

Determination of saposin proteins (sphingolipid activator proteins) in human tissues

Morimoto, S., Yamamoto, Y., O'Brien, J. S. & Kishimoto, Y., 11 1 1990, : : Analytical Biochemistry. 190, 2, p. 154-7 4 p.

研究成果: ジャーナルへの寄稿記事

Sphingolipid Activator Proteins
Saposins
Tissue
Proteins
High Pressure Liquid Chromatography
57 引用 (Scopus)
Sphingolipid Activator Proteins
Saposins
Lysosomal Storage Diseases
Proteins
21 引用 (Scopus)

Effect of chemical modifications of tryptophan residues on the folding of reduced hen egg-white lysozyme

Ueda, T., Yamada, H., Aoki, H. & Imoto, T., 1 1 1990, : : Journal of Biochemistry. 108, 5, p. 886-892 7 p.

研究成果: ジャーナルへの寄稿記事

Egg White
Chemical modification
Muramidase
Tryptophan
hen egg lysozyme
45 引用 (Scopus)

Immunocytochemical study of the surrounding envelope of autophagic vacuoles in cultured rat hepatocytes

Furuno, K., Ishikawa, T., Akasaki, K., Lee, S., Nishimura, Y., Tsuji, H., Himeno, M. & Kato, K., 1 1 1990, : : Experimental Cell Research. 189, 2, p. 261-268 8 p.

研究成果: ジャーナルへの寄稿記事

Vacuoles
Hepatocytes
Membranes
Carboxylesterase
Endoplasmic Reticulum
7 引用 (Scopus)

Immunoenzyme localization of cathepsins in the Golgi region of rat hepatocytes and renal tubule cells

Yokota, S., Nishimura, Y., Kawabata, T. & Kato, K., 11 1 1990, : : Histochemistry. 94, 6, p. 629-635 7 p.

研究成果: ジャーナルへの寄稿記事

cathepsins
Cathepsins
renal tubules
lysosomes
Lysosomes