研究成果 1976 2019

1990
27 引用 (Scopus)

Inhibition of intracellular sorting and processing of lysosomal cathepsins H and L at reduced temperature in primary cultures of rat hepatocytes

Nishimura, Y., Kawabata, T., Yano, S. & Kato, K., 1 1 1990, : : Archives of Biochemistry and Biophysics. 283, 2, p. 458-463 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Cathepsin L
Sorting
Rats
Hepatocytes
59 引用 (Scopus)

Interaction of saposins, acidic lipids, and glucosylceramidase

Morimoto, S., Kishimoto, Y., Tomich, J., Weiler, S., Ohashi, T., Barranger, J. A., Kretz, K. A. & O'Brien, J. S., 2 5 1990, : : Journal of Biological Chemistry. 265, 4, p. 1933-7 5 p.

研究成果: ジャーナルへの寄稿記事

Saposins
Glucosylceramidase
Lipids
Glycoproteins
Enzymes
11 引用 (Scopus)

Lysosomal acid phosphatase is transported via endosomes to lysosomes

Tanaka, Y., Yano, S., Okada, K., Ishikawa, T., Himeno, M. & Kato, K., 2 14 1990, : : Biochemical and Biophysical Research Communications. 166, 3, p. 1176-1182 7 p.

研究成果: ジャーナルへの寄稿記事

Endosomes
Acid Phosphatase
Lysosomes
Horseradish Peroxidase
Methionine
7 引用 (Scopus)

Release of acid phosphatase from lysosomal membranes by cathepsin D

Tanaka, Y., Himeno, M. & Kato, K., 1 1 1990, : : Journal of biochemistry. 108, 2, p. 287-291 5 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
Acid Phosphatase
Membranes
Antipain
Enzymes
1 引用 (Scopus)

Saposins (sphingolipid activator proteins) in the twitcher mutant mouse

Shigematsu, H., Morimoto, S., Kishimoto, Y., Weiler, S., Tomich, J., Barranger, J., Shinohara, M., Yeager, A. M. & O'Brien, J. S., 11 1990, : : Journal of Neurochemistry. 55, 5, p. 1659-62 4 p.

研究成果: ジャーナルへの寄稿記事

Sphingolipid Activator Proteins
Saposins
Galactosylceramidase
Globoid Cell Leukodystrophy
Glucosides
11 引用 (Scopus)

Transport of acid phosphatase to lysosomes does not involve passage through the cell surface

Tanaka, Y., Yano, S., Furuno, K., Ishikawa, T., Himeno, M. & Kato, K., 8 16 1990, : : Biochemical and Biophysical Research Communications. 170, 3, p. 1067-1073 7 p.

研究成果: ジャーナルへの寄稿記事

Acid Phosphatase
Lysosomes
Rats
Hepatocytes
Endosomes
1989
3 引用 (Scopus)

5′-Nucleotidase in Rat Liver Lysosomal Membranes is anchored via Glycosyl-Phosphatidylinositol

Tanaka, Y., Himeno, M., Taguchi, R., Ikezawa, H. & Kato, K., 1 1 1989, : : Cell structure and function. 14, 5, p. 597-603 7 p.

研究成果: ジャーナルへの寄稿記事

Glycosylphosphatidylinositols
5'-Nucleotidase
Membranes
Liver
Phosphoinositide Phospholipase C
37 引用 (Scopus)

Biochemical analysis of the movement of a major lysosomal membrane glycoprotein in the endocytic membrane system

Furuno, K., Yano, S., Akasaki, K., Tanaka, Y., Yamaguchi, Y., Tsuji, H., Himeno, M. & Kato, K., 1 1 1989, : : Journal of biochemistry. 106, 4, p. 717-722 6 p.

研究成果: ジャーナルへの寄稿記事

Lysosome-Associated Membrane Glycoproteins
Membranes
Immunoglobulin G
Lysosomes
Antibodies
11 引用 (Scopus)

Brefeldin A inhibits the targeting of cathepsin D and cathepsin H to lysosomes in rat hepatocytes

Oda, K. & Nishimura, Y., 8 30 1989, : : Biochemical and Biophysical Research Communications. 163, 1, p. 220-225 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Brefeldin A
Cathepsin D
Lysosomes
Rats
57 引用 (Scopus)

Evidence that aspartic proteinase is involved in the proteolytic processing event of procathepsin L in lysosomes

Nishimura, Y., Kawabata, T., Furuno, K. & Kato, K., 1 1 1989, : : Archives of Biochemistry and Biophysics. 271, 2, p. 400-406 7 p.

研究成果: ジャーナルへの寄稿記事

Aspartic Acid Proteases
Lysosomes
Cathepsin L
Processing
Endoplasmic Reticulum
40 引用 (Scopus)

Isolation and sequencing of a cDNA clone encoding 107 kDa sialoglycoprotein in rat liver lysosomal membranes

Himeno, M., Noguchi, Y., Sasaki, H., Tanaka, Y., Furuno, K., Kono, A., Sakaki, Y. & Kato, K., 2 27 1989, : : FEBS Letters. 244, 2, p. 351-356 6 p.

研究成果: ジャーナルへの寄稿記事

Sialoglycoproteins
Liver
Rats
Pancreas
Glycoproteins
20 引用 (Scopus)

Isolation and sequencing of a cDNA clone encoding 96 kDa sialoglycoprotein in rat liver lysosomal membranes

Noguchi, Y., Himeno, M., Sasaki, H., Tanaka, Y., Kono, A., Sakaki, Y. & Kato, K., 11 15 1989, : : Biochemical and Biophysical Research Communications. 164, 3, p. 1113-1120 8 p.

研究成果: ジャーナルへの寄稿記事

Sialoglycoproteins
Liver
Rats
Complementary DNA
Clone Cells
114 引用 (Scopus)

Magnesium and Ammonium-Potassium Lithospermates B, the Active Principles Having a Uremia-Preventive Effect from Salvia miltiorrhiza

Tanaka, T., Morimoto, S., Nonaka, G. I., Nishioka, I., Yokozawa, T., Chung, C., Oura, H. & Young, H., 1 1 1989, : : Chemical and Pharmaceutical Bulletin. 37, 2, p. 340-344 5 p.

研究成果: ジャーナルへの寄稿記事

Salvia miltiorrhiza
Uremia
Ammonium Compounds
Magnesium
Potassium
45 引用 (Scopus)

Morphological localization of a major lysosomal membrane glycoprotein in the endocytic membrane system

Furuno, K., Ishikawa, T., Akasaki, K., Yano, S., Tanaka, Y., Yamaguchi, Y., Tsuji, H., Himeno, M. & Kato, K., 1 1 1989, : : Journal of biochemistry. 106, 4, p. 708-716 9 p.

研究成果: ジャーナルへの寄稿記事

Lysosome-Associated Membrane Glycoproteins
Membranes
Lysosomes
Hepatocytes
Transport Vesicles
120 引用 (Scopus)

Saposin A: second cerebrosidase activator protein

Morimoto, S., Martin, B. M., Yamamoto, Y., Kretz, K. A., O'Brien, J. S. & Kishimoto, Y., 5 1989, : : Proceedings of the National Academy of Sciences of the United States of America. 86, 9, p. 3389-93 5 p.

研究成果: ジャーナルへの寄稿記事

Saposins
Proteins
Galactosylceramidase
Glucosylceramidase
Glucosylceramides

Species difference of UDP-glucuronyltransferase isozymes in liver microsomes

Oguri, K., Ishii, Y., Kojima, K. & Yoshimura, H., 1 1 1989, : : journal of pharmacobio-dynamics. 12, 3, p. s-56

研究成果: ジャーナルへの寄稿会談の抜粋

Glucuronosyltransferase
Liver Microsomes
Isoenzymes
1 引用 (Scopus)

Synthesis and properties of a mercapto[15]annulenone: A 14π diatropic annulene triply characterised by a fast chemical exchange, tautomerisation, and cis-trans-isomerisation

Ogawa, H., Yoshikawa, M., Tanaka, H., Imoto, T., Miyamoto, I., Kato, H., Taniguchi, Y., Nogami, Y. & Koga, T., 1 1 1989, : : Journal of the Chemical Society, Chemical Communications. 8, p. 505-507 3 p.

研究成果: ジャーナルへの寄稿記事

Isomerization
Ion exchange
annulenone
1988
55 引用 (Scopus)

Biosynthesis and processing of lysosomal cathepsin L in primary cultures of rat hepatocytes

Nishimura, Y., Furuno, K. & Kato, K., 5 15 1988, : : Archives of Biochemistry and Biophysics. 263, 1, p. 107-116 10 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
Biosynthesis
Enzyme Precursors
Rats
Hepatocytes
45 引用 (Scopus)

Biosynthesis of lysosomal cathepsins B and H in cultured rat hepatocytes

Nishimura, Y., Amano, J., Sato, H., Tsuji, H. & Kato, K., 4 1988, : : Archives of Biochemistry and Biophysics. 262, 1, p. 159-170 12 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Cathepsin B
Enzyme Precursors
Biosynthesis
Rats
27 引用 (Scopus)

Identification of latent procathepsin H in microsomal lumen: Characterization of proteolytic processing and enzyme activation

Nishimura, Y. & Kato, K., 2 1 1988, : : Archives of Biochemistry and Biophysics. 260, 2, p. 712-718 7 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Enzyme Activation
Peptide Hydrolases
Chemical activation
Enzymes
147 引用 (Scopus)

Identification of latent procathepsins B and L in microsomal lumen: Characterization of enzymatic activation and proteolytic processing in vitro

Nishimura, Y., Kawabata, T. & Kato, K., 2 15 1988, : : Archives of Biochemistry and Biophysics. 261, 1, p. 64-71 8 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Chemical activation
Cathepsin D
Cathepsin L
Processing
16 引用 (Scopus)

Localization of cathepsin L in rat kidney revealed by immunoenzyme and immunogold techniques

Yokota, S., Nishimura, Y. & Kato, K., 7 1 1988, : : Histochemistry. 90, 4, p. 277-283 7 p.

研究成果: ジャーナルへの寄稿記事

cathepsin L
Cathepsin L
Immunoenzyme Techniques
proximal tubules
Immunohistochemistry
14 引用 (Scopus)

Prenylated flavan-3-ols and procyanidins from Illicium anisatum

Morimoto, S., Tanabe, H., Nonaka, G. I. & Nishioka, I., 1988, : : Phytochemistry. 27, 3, p. 907-910 4 p.

研究成果: ジャーナルへの寄稿記事

Illicium anisatum
Illicium
Proanthocyanidins
procyanidins
Catechin
92 引用 (Scopus)

Saposin D: a sphingomyelinase activator

Morimoto, S., Martin, B. M., Kishimoto, Y. & O'Brien, J. S., 10 14 1988, : : Biochemical and Biophysical Research Communications. 156, 1, p. 403-10 8 p.

研究成果: ジャーナルへの寄稿記事

Saposins
Sphingomyelin Phosphodiesterase
Amino Acid Sequence
Amino Acids
Protein Precursors
9 引用 (Scopus)

Structures of sugar chains of a p-nitrophenyl acetate-hydrolyzing esterase from the microsomes of rat liver

Natsuka, S., Himeno, M., Hase, S., Ito, H., Ueda, T., Kato, K. & Ikenaka, T., 1 1 1988, : : Journal of biochemistry. 103, 6, p. 986-991 6 p.

研究成果: ジャーナルへの寄稿記事

Acetylesterase
Liver Microsomes
Esterases
Sugars
Liver
5 引用 (Scopus)
nucleosides
eggs
Nucleosides
esters
ethers
17 引用 (Scopus)
Hares
Stearates
Aplysia
Cholesterol Esters
Palmitates
14 引用 (Scopus)

Studies on the constituents of marine opisthobranchia, IV. Two new polyhalogenated monoterpenes from the sea hare Aplysia kurodai

Miyamoto, T., Higuchi, R., Marubayashi, N. & Komori, T., 1 1 1988, : : Liebigs Annalen der Chemie. 1988, 12, p. 1191-1193 3 p.

研究成果: ジャーナルへの寄稿記事

mollusks
Monoterpenes
31 引用 (Scopus)
Vaccinium vitis-idaea
Proanthocyanidins
Catechin
Tannins
Ericaceae
50 引用 (Scopus)

Tannins and Related Compounds. LXI.1) Isolation and Structures of Novel Bi- and Triflavanoids from the Leaves of Cassia fistula L.

Morimoto, S., Nonaka, G. I., Chen, R. F. & Nishioka, I., 1 1 1988, : : Chemical and Pharmaceutical Bulletin. 36, 1, p. 39-47 9 p.

研究成果: ジャーナルへの寄稿記事

Cassia
Tannins
Proanthocyanidins
Catechin
Glucosides
1987
6 引用 (Scopus)

Highly controlled carbodiimide reaction for the modification of lysozyme. Modification of leu129 or asp119

Ueda, T., Yamada, H. & Imoto, T., 6 1 1987, : : Protein Engineering, Design and Selection. 1, 3, p. 189-193 5 p.

研究成果: ジャーナルへの寄稿記事

Carbodiimides
Muramidase
Enzymes
Salts
Glucosamine
36 引用 (Scopus)
Cathepsin D
Chemical activation
Processing
Biosynthesis
Immunoblotting
26 引用 (Scopus)

Intracellular transport and processing of lysosomal cathepsin B

Nishimura, Y. & Kato, K., 10 14 1987, : : Biochemical and Biophysical Research Communications. 148, 1, p. 254-259 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin B
Lysosomes
Processing
Subcellular Fractions
Golgi Apparatus
27 引用 (Scopus)

Intracellular transport and processing of lysosomal cathepsin H

Nishimura, Y. & Kato, K., 10 14 1987, : : Biochemical and Biophysical Research Communications. 148, 1, p. 329-334 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Lysosomes
Subcellular Fractions
Golgi Apparatus
Processing
22 引用 (Scopus)

In vitro biosynthesis of the lysosomal cathepsin H

Nishimura, Y. & Kato, K., 7 15 1987, : : Biochemical and Biophysical Research Communications. 146, 1, p. 159-164 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Biosynthesis
Enzyme Precursors
Membranes
Polyribosomes
10 引用 (Scopus)

Modifications of stability and function of lysozyme

Imoto, T., Yamada, H., Okazaki, K., Ueda, T., Kuroki, R. & Yasukochi, T., 4 1 1987, : : Journal of Protein Chemistry. 6, 2, p. 95-107 13 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Enzymes
Conformations
Catalytic Domain
Proteins
5 引用 (Scopus)

pH Dependence of Individual Tryptophan N-1 Hydrogen Exchange Rates in Lysozyme and Its Chemically Modified Derivatives

Endo, T., Ueda, T., Yamada, H. & Imoto, T., 1 1 1987, : : Biochemistry. 26, 7, p. 1838-1845 8 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Tryptophan
Hydrogen
Derivatives
Protein Denaturation
27 引用 (Scopus)

Point mutation of alanine (31) to valine prohibits the folding of reduced lysozyme by sulfhydryl-disulfide interchange

Imoto, T., Yamada, H., Yasukochi, T., Yamada, E., Ito, Y., Ueda, T., Nagatani, H., Miki, T. & Horiuchi, T., 8 1 1987, : : Protein Engineering, Design and Selection. 1, 4, p. 333-338 6 p.

研究成果: ジャーナルへの寄稿記事

Valine
Interchanges
Muramidase
Point Mutation
Disulfides
38 引用 (Scopus)

Tannins and Related Compounds. L.1) Structures of Proanthocyanidin A-l and Related Compounds

Nonaka, G. I., Morimoto, S., Nishioka, I., Kinjo, J. E. & Nohara, T., 1 1 1987, : : Chemical and Pharmaceutical Bulletin. 35, 1, p. 149-155 7 p.

研究成果: ジャーナルへの寄稿記事

Tannins
Proanthocyanidins
proanthocyanidin
proanthocyanidin A1
53 引用 (Scopus)

Tannins and Related Compounds. LIX.1)Aesculitannins, Novel Proanthocyanidins with Doubly-Bonded Structures from Aesculus hippocastanum L.

Morimoto, S., Nonaka, G. I. & Nishioka, I., 1 1 1987, : : Chemical and Pharmaceutical Bulletin. 35, 12, p. 4717-4729 13 p.

研究成果: ジャーナルへの寄稿記事

Aesculus
Proanthocyanidins
Catechin
Tannins
varespladib methyl
1986
17 引用 (Scopus)

Elaeocarpusin, A Proto-Type of Geraniin From Geranium Thunbergii

Nonaka, G., Morimoto, S. & Nishioka, I., 1 1 1986, : : Chemical and Pharmaceutical Bulletin. 34, 2, p. 941-943 3 p.

研究成果: ジャーナルへの寄稿記事

Geranium
Hydrolyzable Tannins
Quinic Acid
Dehydroascorbic Acid
Metabolism
38 引用 (Scopus)

Isolation and structures of aplykurodins a and b, two new isoprenoids from the marine mollusk aplysia kurodai

Miyamoto, T., Higuchi, R., Komori, T., Fujioka, T. & Mihashi, K., 1986, : : Tetrahedron Letters. 27, 10, p. 1153-1156 4 p.

研究成果: ジャーナルへの寄稿記事

Aplysia
Mollusca
Terpenes
X-Rays
X rays
29 引用 (Scopus)
Cinnamomum aromaticum
Proanthocyanidins
Tannins
Glucosides
varespladib methyl
101 引用 (Scopus)
Cinnamomum aromaticum
Cassia
Proanthocyanidins
Catechin
Tannins
80 引用 (Scopus)

Unfolding rates of globular proteins determined by kinetics of proteolysis

Imoto, T., Yamada, H. & Ueda, T., 8 20 1986, : : Journal of Molecular Biology. 190, 4, p. 647-649 3 p.

研究成果: ジャーナルへの寄稿記事

Proteolysis
Digestion
Peptide Hydrolases
Muramidase
Pancreatic Ribonuclease
1985
36 引用 (Scopus)
Muramidase
Histidine
Lysine
Derivatives
Stabilization
39 引用 (Scopus)

Isolation and Characterization of 101-β-Lysozyme That Possesses the β-Aspartyl Sequence at Aspartic Acid-101

Yamada, H., Ueda, T., Kuroki, R., Fukumura, T., Yasukochi, T., Hirabayashi, T., Fujita, K. & Imoto, T., 12 1 1985, : : Biochemistry. 24, 27, p. 7953-7959 7 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Aspartic Acid
Biochemistry
Diatomaceous Earth
Derivatives
30 引用 (Scopus)

Tannins and Related Compounds. Proanthocyanidins with a Doubly Linked Unit from the Root Bark of Cinnamomum sieboldii Meisner

Morimoto, S., Nonaka, G. I. & Nishioka, I., 1 1 1985, : : Chemical and Pharmaceutical Bulletin. 33, 10, p. 4338-4345 8 p.

研究成果: ジャーナルへの寄稿記事

Cinnamomum
Proanthocyanidins
Catechin
Tannins
Lauraceae
61 引用 (Scopus)
Lindera
Cinnamomum aromaticum
Catechin
Tannins
Cinnamomum
1983
4 引用 (Scopus)

Cannabis. XV. preparation and stability of Δ9-tetrahydrocannabinol-β-cyclodextrin inclusion complex

Shoyama, Y., Morimoto, S. & Nishioka, I., 1 1 1983, : : Journal of Natural Products. 46, 5, p. 633-637 5 p.

研究成果: ジャーナルへの寄稿記事

Dronabinol
Cyclodextrins
Cannabis
Drug Delivery Systems
Oxygen