研究成果 1976 2019

1992
26 引用 (Scopus)

Isolation and sequencing of a cDNA clone encoding the 85 kDa human lysosomal sialoglycoprotein (hLGP85) in human metastatic pancreas islet tumor cells

Fujita, H., Takata, Y., Kono, A., Tanaka, Y., Takahashi, T., Himeno, M. & Kato, K., 4 30 1992, : : Biochemical and Biophysical Research Communications. 184, 2, p. 604-611 8 p.

研究成果: ジャーナルへの寄稿記事

Sialoglycoproteins
Islet Cell Adenoma
Rats
Tumors
Pancreas
1 引用 (Scopus)

Possible involvement of cathepsin L in processing of rat liver hexokinase to eliminate mitochondria-binding ability

Okazaki, H., Tanl, C., Ando, M., Ishii, K., Ishibashi, S., Nishimura, Y. & Kato, K., 1 1 1992, : : Journal of biochemistry. 112, 3, p. 409-413 5 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
Mitochondria
Hexokinase
Liver
Rats
31 引用 (Scopus)

Structures of four new triterpenoid oligoglycosides: DS-penaustrosides A, B, C, and D from the sea cucumber pentacta australis

Miyamoto, T., Togawa, K., Higuchi, R., Komori, T. & Sasaki, T., 7 1 1992, : : Journal of Natural Products. 55, 7, p. 940-946 7 p.

研究成果: ジャーナルへの寄稿記事

Sea Cucumbers
Glycosides
19 引用 (Scopus)

Three new cytotoxic sesterterpenoids, inorolide A, B, and C from the nudibranch Chromodoris inornata

Miyamoto, T., Sakamoto, K., Amano, H., Higuchi, R., Komori, T. & Sasaki, T., 9 22 1992, : : Tetrahedron Letters. 33, 39, p. 5811-5814 4 p.

研究成果: ジャーナルへの寄稿記事

X-Rays
Single crystals
X rays
1991
3 引用 (Scopus)

1H-NMR study of the intramolecular interaction of a substrate analogue covalently attached to aspartic acid-101 in lysozyme

Ueda, T., Isakari, Y., Aoki, H., Yasukochi, T., Masutomo, S. I., Kawano, K., Terada, Y., Yamada, H. & Imoto, T., 1 1 1991, : : Journal of Biochemistry. 109, 5, p. 690-698 9 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Aspartic Acid
Nuclear magnetic resonance
Catalytic Domain
Substrates
41 引用 (Scopus)

Bafilomycin A1 inhibits the targeting of lysosomal acid hydrolases in cultured hepatocytes

Oda, K., Nishimura, Y., Ikehara, Y. & Kato, K., 7 15 1991, : : Biochemical and Biophysical Research Communications. 178, 1, p. 369-377 9 p.

研究成果: ジャーナルへの寄稿記事

Hydrolases
Hepatocytes
Acids
Cathepsin H
Vacuolar Proton-Translocating ATPases
35 引用 (Scopus)

Isolation and sequencing of a cDNA clone encoding rat liver lysosomal cathepsin D and the structure of three forms of mature enzymes

Fujita, H., Tanaka, Y., Noguchi, Y., Kono, A., Himeno, M. & Kato, K., 8 30 1991, : : Biochemical and Biophysical Research Communications. 179, 1, p. 190-196 7 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
Liver
Rats
Complementary DNA
Clone Cells
4 引用 (Scopus)

Mechanisms of a conversion from membrane associated lysosomal acid phosphatase to content forms

Himeno, M., Nakamura, K., Tanaka, Y., Yamada, H., Imoto, T. & Kato, K., 11 14 1991, : : Biochemical and Biophysical Research Communications. 180, 3, p. 1483-1489 7 p.

研究成果: ジャーナルへの寄稿記事

Acid Phosphatase
Cathepsin D
Membranes
Enzymes
Lysosomes
35 引用 (Scopus)

Multiple proteolytic action of rat liver cathepsin B: Specificities and pH-dependences of the endo- and exopeptidase activities

Koga, H., Yamada, H., Nishimura, Y., Kato, K. & Imoto, T., 1 1 1991, : : Journal of Biochemistry. 110, 2, p. 179-188 10 p.

研究成果: ジャーナルへの寄稿記事

Exopeptidases
Endopeptidases
Cathepsin B
Carboxypeptidases
Liver
19 引用 (Scopus)

Preparation and properties of a lysozyme derivative in which two domains are cross-linked intramolecularly between trp62 and asp101

Ueda, T., Yamada, H., Sakamoto, N., Abe, Y., Kawano, K., Terada, Y. & Imoto, T., 1 1 1991, : : Journal of biochemistry. 110, 5, p. 719-725 7 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Derivatives
Chromatography
Carbodiimides
Micrococcus
4 引用 (Scopus)

Rat cathepsin H-catalyzed transacylation: Comparisons of the mechanism and the specificity with papain-superfamily proteases

Koga, H., Mori, N., Yamada, H., Nishimura, Y., Tokuda, K., Kato, K. & Imoto, T., 1 1 1991, : : Journal of Biochemistry. 110, 6, p. 939-944 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Papain
Amides
Rats
Peptide Hydrolases
1990
23 引用 (Scopus)

Augmented excretion of procathepsin L of a fos-transferred highly metastatic rat cell line

Taniguchi, S., Nishimura, Y., Takahashi, T., Baba, T. & Kato, K., 4 30 1990, : : Biochemical and Biophysical Research Communications. 168, 2, p. 520-526 7 p.

研究成果: ジャーナルへの寄稿記事

Rats
Cells
4 alpha-glucanotransferase
Cell Line
fos Genes
22 引用 (Scopus)

Biosythesis processing, and intracellular transport of lysosomal acid phosphatase in rat hepatocytes

Tanaka, Y., Harada, R., Himeno, M. & Kato, K., 1 1 1990, : : Journal of biochemistry. 108, 2, p. 278-286 9 p.

研究成果: ジャーナルへの寄稿記事

Acid Phosphatase
Rats
Hepatocytes
Lysosomes
Processing
103 引用 (Scopus)

Characterization of a mutation in a family with saposin B deficiency: a glycosylation site defect

Kretz, K. A., Carson, G. S., Morimoto, S., Kishimoto, Y., Fluharty, A. L. & O'Brien, J. S., 4 1990, : : Proceedings of the National Academy of Sciences of the United States of America. 87, 7, p. 2541-4 4 p.

研究成果: ジャーナルへの寄稿記事

Saposins
Glycosylation
Mutation
Metachromatic Leukodystrophy
Isoleucine
26 引用 (Scopus)

Comparative study on specificities of rat cathepsin L and papain: Amino acid differences at substrate-binding sites are involved in their specificities

Koga, H., Yamada, H., Nishimura, Y., Kato, K. & Imoto, T., 1 1 1990, : : Journal of Biochemistry. 108, 6, p. 976-982 7 p.

研究成果: ジャーナルへの寄稿記事

Papain
Cathepsin L
Binding Sites
Amino Acids
Substrates
7 引用 (Scopus)
glucosides
Glycosides
isolation
44 引用 (Scopus)

Constituents of holothuroidea, II. Six newly identified biologically active triterpenoid glycoside sulfates from the sea cucumber Cucumaria echinata

Miyamoto, T., Togawa, K., Higuchi, R., Komori, T. & Sasaki, T., 1 1 1990, : : Liebigs Annalen der Chemie. 1990, 5, p. 453-460 8 p.

研究成果: ジャーナルへの寄稿記事

Cucumaria
Sea Cucumbers
KB Cells
Glycosides
Sulfates
13 引用 (Scopus)

Determination of saposin proteins (sphingolipid activator proteins) in human tissues

Morimoto, S., Yamamoto, Y., O'Brien, J. S. & Kishimoto, Y., 11 1 1990, : : Analytical Biochemistry. 190, 2, p. 154-7 4 p.

研究成果: ジャーナルへの寄稿記事

Sphingolipid Activator Proteins
Saposins
Tissue
Proteins
High Pressure Liquid Chromatography
57 引用 (Scopus)
Sphingolipid Activator Proteins
Saposins
Lysosomal Storage Diseases
Proteins
21 引用 (Scopus)

Effect of chemical modifications of tryptophan residues on the folding of reduced hen egg-white lysozyme

Ueda, T., Yamada, H., Aoki, H. & Imoto, T., 1 1 1990, : : Journal of Biochemistry. 108, 5, p. 886-892 7 p.

研究成果: ジャーナルへの寄稿記事

Egg White
Chemical modification
Muramidase
Tryptophan
hen egg lysozyme
45 引用 (Scopus)

Immunocytochemical study of the surrounding envelope of autophagic vacuoles in cultured rat hepatocytes

Furuno, K., Ishikawa, T., Akasaki, K., Lee, S., Nishimura, Y., Tsuji, H., Himeno, M. & Kato, K., 1 1 1990, : : Experimental Cell Research. 189, 2, p. 261-268 8 p.

研究成果: ジャーナルへの寄稿記事

Vacuoles
Hepatocytes
Membranes
Carboxylesterase
Endoplasmic Reticulum
7 引用 (Scopus)

Immunoenzyme localization of cathepsins in the Golgi region of rat hepatocytes and renal tubule cells

Yokota, S., Nishimura, Y., Kawabata, T. & Kato, K., 11 1990, : : Histochemistry. 94, 6, p. 629-635 7 p.

研究成果: ジャーナルへの寄稿記事

cathepsins
Cathepsins
renal tubules
lysosomes
Lysosomes
27 引用 (Scopus)

Inhibition of intracellular sorting and processing of lysosomal cathepsins H and L at reduced temperature in primary cultures of rat hepatocytes

Nishimura, Y., Kawabata, T., Yano, S. & Kato, K., 1 1 1990, : : Archives of Biochemistry and Biophysics. 283, 2, p. 458-463 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Cathepsin L
Sorting
Rats
Hepatocytes
59 引用 (Scopus)

Interaction of saposins, acidic lipids, and glucosylceramidase

Morimoto, S., Kishimoto, Y., Tomich, J., Weiler, S., Ohashi, T., Barranger, J. A., Kretz, K. A. & O'Brien, J. S., 2 5 1990, : : Journal of Biological Chemistry. 265, 4, p. 1933-7 5 p.

研究成果: ジャーナルへの寄稿記事

Saposins
Glucosylceramidase
Lipids
Glycoproteins
Enzymes
11 引用 (Scopus)

Lysosomal acid phosphatase is transported via endosomes to lysosomes

Tanaka, Y., Yano, S., Okada, K., Ishikawa, T., Himeno, M. & Kato, K., 2 14 1990, : : Biochemical and Biophysical Research Communications. 166, 3, p. 1176-1182 7 p.

研究成果: ジャーナルへの寄稿記事

Endosomes
Acid Phosphatase
Lysosomes
Horseradish Peroxidase
Methionine
7 引用 (Scopus)

Release of acid phosphatase from lysosomal membranes by cathepsin D

Tanaka, Y., Himeno, M. & Kato, K., 1 1 1990, : : Journal of biochemistry. 108, 2, p. 287-291 5 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin D
Acid Phosphatase
Membranes
Antipain
Enzymes
1 引用 (Scopus)

Saposins (sphingolipid activator proteins) in the twitcher mutant mouse

Shigematsu, H., Morimoto, S., Kishimoto, Y., Weiler, S., Tomich, J., Barranger, J., Shinohara, M., Yeager, A. M. & O'Brien, J. S., 11 1990, : : Journal of Neurochemistry. 55, 5, p. 1659-62 4 p.

研究成果: ジャーナルへの寄稿記事

Sphingolipid Activator Proteins
Saposins
Galactosylceramidase
Globoid Cell Leukodystrophy
Glucosides
11 引用 (Scopus)

Transport of acid phosphatase to lysosomes does not involve passage through the cell surface

Tanaka, Y., Yano, S., Furuno, K., Ishikawa, T., Himeno, M. & Kato, K., 8 16 1990, : : Biochemical and Biophysical Research Communications. 170, 3, p. 1067-1073 7 p.

研究成果: ジャーナルへの寄稿記事

Acid Phosphatase
Lysosomes
Rats
Hepatocytes
Endosomes
1989
3 引用 (Scopus)

5′-Nucleotidase in Rat Liver Lysosomal Membranes is anchored via Glycosyl-Phosphatidylinositol

Tanaka, Y., Himeno, M., Taguchi, R., Ikezawa, H. & Kato, K., 1 1 1989, : : Cell structure and function. 14, 5, p. 597-603 7 p.

研究成果: ジャーナルへの寄稿記事

Glycosylphosphatidylinositols
5'-Nucleotidase
Membranes
Liver
Phosphoinositide Phospholipase C
37 引用 (Scopus)

Biochemical analysis of the movement of a major lysosomal membrane glycoprotein in the endocytic membrane system

Furuno, K., Yano, S., Akasaki, K., Tanaka, Y., Yamaguchi, Y., Tsuji, H., Himeno, M. & Kato, K., 1 1 1989, : : Journal of biochemistry. 106, 4, p. 717-722 6 p.

研究成果: ジャーナルへの寄稿記事

Lysosome-Associated Membrane Glycoproteins
Membranes
Immunoglobulin G
Lysosomes
Antibodies
11 引用 (Scopus)

Brefeldin A inhibits the targeting of cathepsin D and cathepsin H to lysosomes in rat hepatocytes

Oda, K. & Nishimura, Y., 8 30 1989, : : Biochemical and Biophysical Research Communications. 163, 1, p. 220-225 6 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Brefeldin A
Cathepsin D
Lysosomes
Rats
56 引用 (Scopus)

Evidence that aspartic proteinase is involved in the proteolytic processing event of procathepsin L in lysosomes

Nishimura, Y., Kawabata, T., Furuno, K. & Kato, K., 1 1 1989, : : Archives of Biochemistry and Biophysics. 271, 2, p. 400-406 7 p.

研究成果: ジャーナルへの寄稿記事

Aspartic Acid Proteases
Lysosomes
Cathepsin L
Processing
Endoplasmic Reticulum
8 引用 (Scopus)

Genetic suppression of a dnaG mutation in Escherichia coli

Katayama, T., Murakami, Y., Wada, C., Ohmori, H., Yura, T. & Nagata, T., 1 1 1989, : : Journal of bacteriology. 171, 3, p. 1485-1491 7 p.

研究成果: ジャーナルへの寄稿記事

DNA Primase
Genetic Suppression
Escherichia coli
Mutation
Genes
40 引用 (Scopus)

Isolation and sequencing of a cDNA clone encoding 107 kDa sialoglycoprotein in rat liver lysosomal membranes

Himeno, M., Noguchi, Y., Sasaki, H., Tanaka, Y., Furuno, K., Kono, A., Sakaki, Y. & Kato, K., 2 27 1989, : : FEBS Letters. 244, 2, p. 351-356 6 p.

研究成果: ジャーナルへの寄稿記事

Sialoglycoproteins
Liver
Rats
Pancreas
Glycoproteins
20 引用 (Scopus)

Isolation and sequencing of a cDNA clone encoding 96 kDa sialoglycoprotein in rat liver lysosomal membranes

Noguchi, Y., Himeno, M., Sasaki, H., Tanaka, Y., Kono, A., Sakaki, Y. & Kato, K., 11 15 1989, : : Biochemical and Biophysical Research Communications. 164, 3, p. 1113-1120 8 p.

研究成果: ジャーナルへの寄稿記事

Sialoglycoproteins
Liver
Rats
Complementary DNA
Clone Cells
114 引用 (Scopus)

Magnesium and Ammonium-Potassium Lithospermates B, the Active Principles Having a Uremia-Preventive Effect from Salvia miltiorrhiza

Tanaka, T., Morimoto, S., Nonaka, G. I., Nishioka, I., Yokozawa, T., Chung, C., Oura, H. & Young, H., 1 1 1989, : : Chemical and Pharmaceutical Bulletin. 37, 2, p. 340-344 5 p.

研究成果: ジャーナルへの寄稿記事

Salvia miltiorrhiza
Uremia
Ammonium Compounds
Magnesium
Potassium
45 引用 (Scopus)

Morphological localization of a major lysosomal membrane glycoprotein in the endocytic membrane system

Furuno, K., Ishikawa, T., Akasaki, K., Yano, S., Tanaka, Y., Yamaguchi, Y., Tsuji, H., Himeno, M. & Kato, K., 1 1 1989, : : Journal of biochemistry. 106, 4, p. 708-716 9 p.

研究成果: ジャーナルへの寄稿記事

Lysosome-Associated Membrane Glycoproteins
Membranes
Lysosomes
Hepatocytes
Transport Vesicles
120 引用 (Scopus)

Saposin A: second cerebrosidase activator protein

Morimoto, S., Martin, B. M., Yamamoto, Y., Kretz, K. A., O'Brien, J. S. & Kishimoto, Y., 5 1989, : : Proceedings of the National Academy of Sciences of the United States of America. 86, 9, p. 3389-93 5 p.

研究成果: ジャーナルへの寄稿記事

Saposins
Proteins
Galactosylceramidase
Glucosylceramidase
Glucosylceramides

Species difference of UDP-glucuronyltransferase isozymes in liver microsomes

Oguri, K., Ishii, Y., Kojima, K. & Yoshimura, H., 1 1 1989, : : journal of pharmacobio-dynamics. 12, 3

研究成果: ジャーナルへの寄稿会談の抜粋

Glucuronosyltransferase
Liver Microsomes
Isoenzymes
1 引用 (Scopus)

Synthesis and properties of a mercapto[15]annulenone: A 14π diatropic annulene triply characterised by a fast chemical exchange, tautomerisation, and cis-trans-isomerisation

Ogawa, H., Yoshikawa, M., Tanaka, H., Imoto, T., Miyamoto, I., Kato, H., Taniguchi, Y., Nogami, Y. & Koga, T., 1 1 1989, : : Journal of the Chemical Society, Chemical Communications. 8, p. 505-507 3 p.

研究成果: ジャーナルへの寄稿記事

Isomerization
Ion exchange
annulenone
1988
55 引用 (Scopus)

Biosynthesis and processing of lysosomal cathepsin L in primary cultures of rat hepatocytes

Nishimura, Y., Furuno, K. & Kato, K., 5 15 1988, : : Archives of Biochemistry and Biophysics. 263, 1, p. 107-116 10 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
Biosynthesis
Enzyme Precursors
Rats
Hepatocytes
45 引用 (Scopus)

Biosynthesis of lysosomal cathepsins B and H in cultured rat hepatocytes

Nishimura, Y., Amano, J., Sato, H., Tsuji, H. & Kato, K., 1 1 1988, : : Archives of Biochemistry and Biophysics. 262, 1, p. 159-170 12 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin H
Cathepsin B
Enzyme Precursors
Biosynthesis
Rats
27 引用 (Scopus)

Identification of latent procathepsin H in microsomal lumen: Characterization of proteolytic processing and enzyme activation

Nishimura, Y. & Kato, K., 2 1 1988, : : Archives of Biochemistry and Biophysics. 260, 2, p. 712-718 7 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Enzyme Activation
Peptide Hydrolases
Chemical activation
Enzymes
147 引用 (Scopus)

Identification of latent procathepsins B and L in microsomal lumen: Characterization of enzymatic activation and proteolytic processing in vitro

Nishimura, Y., Kawabata, T. & Kato, K., 2 15 1988, : : Archives of Biochemistry and Biophysics. 261, 1, p. 64-71 8 p.

研究成果: ジャーナルへの寄稿記事

Enzyme Precursors
Chemical activation
Cathepsin D
Cathepsin L
Processing
16 引用 (Scopus)

Localization of cathepsin L in rat kidney revealed by immunoenzyme and immunogold techniques

Yokota, S., Nishimura, Y. & Kato, K., 7 1 1988, : : Histochemistry. 90, 4, p. 277-283 7 p.

研究成果: ジャーナルへの寄稿記事

cathepsin L
Cathepsin L
Immunoenzyme Techniques
proximal tubules
Immunohistochemistry
14 引用 (Scopus)

Prenylated flavan-3-ols and procyanidins from Illicium anisatum

Morimoto, S., Tanabe, H., Nonaka, G. I. & Nishioka, I., 1988, : : Phytochemistry. 27, 3, p. 907-910 4 p.

研究成果: ジャーナルへの寄稿記事

Illicium anisatum
Illicium
Proanthocyanidins
procyanidins
Catechin
92 引用 (Scopus)

Saposin D: a sphingomyelinase activator

Morimoto, S., Martin, B. M., Kishimoto, Y. & O'Brien, J. S., 10 14 1988, : : Biochemical and Biophysical Research Communications. 156, 1, p. 403-10 8 p.

研究成果: ジャーナルへの寄稿記事

Saposins
Sphingomyelin Phosphodiesterase
Amino Acid Sequence
Amino Acids
Protein Precursors
9 引用 (Scopus)

Structures of sugar chains of a p-nitrophenyl acetate-hydrolyzing esterase from the microsomes of rat liver

Natsuka, S., Himeno, M., Hase, S., Ito, H., Ueda, T., Kato, K. & Ikenaka, T., 1 1 1988, : : Journal of biochemistry. 103, 6, p. 986-991 6 p.

研究成果: ジャーナルへの寄稿記事

Acetylesterase
Liver Microsomes
Esterases
Sugars
Liver
5 引用 (Scopus)
nucleosides
eggs
Nucleosides
esters
ethers
17 引用 (Scopus)
Hares
Stearates
Aplysia
Cholesterol Esters
Palmitates