研究成果 1976 2020

記事
2 引用 (Scopus)

Different expression systems resulted in varied binding properties of anti-paclitaxel single-chain variable fragment antibody clone 1C2

Yusakul, G., Sakamoto, S., Nuntawong, P., Tanaka, H. & Morimoto, S., 1 1 2018, : : Journal of Natural Medicines. 72, 1, p. 310-316 7 p.

研究成果: ジャーナルへの寄稿記事

Single-Chain Antibodies
Paclitaxel
Bombyx
Clone Cells
Escherichia coli
32 引用 (Scopus)

Differential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypes

Iwabu, Y., Kinomoto, M., Tatsumi, M., Fujita, H., Shimura, M., Tanaka, Y., Ishizaka, Y., Nolan, D., Mallal, S., Sata, T. & Tokunaga, K., 11 12 2010, : : Journal of Biological Chemistry. 285, 46, p. 35350-35358 9 p.

研究成果: ジャーナルへの寄稿記事

vif Gene Products
HIV-1
vif Genes
Cytidine Deaminase
Lymphocytes
11 引用 (Scopus)

Differential Effect of Membrane Composition on the Pore-Forming Ability of Four Different Sea Anemone Actinoporins

García-Linares, S., Rivera-De-Torre, E., Morante, K., Tsumoto, K., Caaveiro, J. M. M., Gavilanes, J. G., Slotte, J. P. & Martínez-Del-Pozo, Á., 12 6 2016, : : Biochemistry. 55, 48, p. 6630-6641 12 p.

研究成果: ジャーナルへの寄稿記事

Sea Anemones
Aptitude
Sphingomyelins
Membranes
Chemical analysis
8 引用 (Scopus)

Differential expression of MHC class II antigens and cathepsin L by subtypes of cortical epithelial cells in the rat thymus: An immunoelectron microscopic study

Arudchelvan, Y., Nishimura, Y., Tokuda, N., Sawada, T., Shinozaki, F. & Fukumoto, T., 7 8 2002, : : Journal of Electron Microscopy. 51, 3, p. 173-181 9 p.

研究成果: ジャーナルへの寄稿記事

Cathepsin L
Thymus
Histocompatibility Antigens Class II
antigens
Antigens
64 引用 (Scopus)

Differential interaction of equinatoxin II with model membranes in response to lipid composition

Caaveiro, J. M. M., Echabe, I., Gutiérrez-Aguirre, I., Nieva, J. L., Arrondo, J. L. R. & González-Mañas, J. M., 1 1 2001, : : Biophysical Journal. 80, 3, p. 1343-1353 11 p.

研究成果: ジャーナルへの寄稿記事

Unilamellar Liposomes
Sphingomyelins
Phosphatidylcholines
Lipids
Membranes
34 引用 (Scopus)

Differentiation of the DnaA-oriC subcomplex for DNA unwinding in a replication initiation complex

Ozaki, S., Noguchi, Y., Hayashi, Y., Miyazaki, E. & Katayama, T., 10 26 2012, : : Journal of Biological Chemistry. 287, 44, p. 37458-37471 14 p.

研究成果: ジャーナルへの寄稿記事

DNA
Molecules
7 引用 (Scopus)

Dioleoyl-phosphatidic acid selectively binds to α-synuclein and strongly induces its aggregation

Mizuno, S., Sasai, H., Kume, A., Takahashi, D., Satoh, M., Kado, S. & Sakane, F., 3 2017, : : FEBS Letters. 591, 5, p. 784-791 8 p.

研究成果: ジャーナルへの寄稿記事

Synucleins
Phosphatidic Acids
Agglomeration
Endopeptidase K
Proteins
12 引用 (Scopus)

Dioxin-induced fetal growth retardation: the role of a preceding attenuation in the circulating level of glucocorticoid

Hattori, Y., Takeda, T., Fujii, M., Taura, J., Ishii, Y. & Yamada, H., 10 21 2014, : : Endocrine. 47, 2, p. 572-580 9 p.

研究成果: ジャーナルへの寄稿記事

Dioxins
Fetal Growth Retardation
Glucocorticoids
Growth Hormone
Fetus
7 引用 (Scopus)

Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration

Takeda, T., Komiya, Y., Koga, T., Ishida, T., Ishii, Y., Kikuta, Y., Nakaya, M., Kurose, H., Yokomizo, T., Shimizu, T., Uchi, H., Furue, M. & Yamada, H., 1 1 2017, : : Journal of Biological Chemistry. 292, 25, p. 10586-10599 14 p.

研究成果: ジャーナルへの寄稿記事

Aryl Hydrocarbon Receptors
Dioxins
Leukotriene B4
Neutrophil Infiltration
Biosynthesis
13 引用 (Scopus)
Aryl Hydrocarbon Receptors
Dioxins
Pituitary Hormones
Gonadotropins
Growth Hormone
5 引用 (Scopus)

Dioxin-produced alteration in the profiles of fecal and urinary metabolomes: A change in bile acids and its relevance to toxicity

Kakizuka, S., Takeda, T., Komiya, Y., Koba, A., Uchi, H., Yamamoto, M., Furue, M., Ishii, Y. & Yamada, H., 10 1 2015, : : Biological and Pharmaceutical Bulletin. 38, 10, p. 1484-1495 12 p.

研究成果: ジャーナルへの寄稿記事

Dioxins
Metabolome
Bile Acids and Salts
Chenodeoxycholic Acid
Cholic Acid
25 引用 (Scopus)

Dioxin silences gonadotropin expression in perinatal pups by inducing histone deacetylases: A new insight into the mechanism for the imprinting of sexual immaturity by dioxin

Takeda, T., Fujii, M., Taura, J., Ishii, Y. & Yamada, H., 5 25 2012, : : Journal of Biological Chemistry. 287, 22, p. 18440-18450 11 p.

研究成果: ジャーナルへの寄稿記事

Dioxins
Histone Deacetylases
Gonadotropins
Luteinizing Hormone
Histones
7 引用 (Scopus)

Direct determination of naturally occurring biologically active compound-serum albumin conjugate by matrix-assisted laser desorption/ionization mass spectrometry

Tanaka, H., Xuan, L. J., Morimoto, S., Shoyama, Y., Isobe, R. & Nojima, K., 1 1 2001, : : Spectroscopy. 15, 1, p. 1-18 18 p.

研究成果: ジャーナルへの寄稿記事

Bovine Serum Albumin
Serum Albumin
Ionization
Mass spectrometry
Desorption
3 引用 (Scopus)

Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1

Tashiro, S., Caaveiro, J. M. M., Nakakido, M., Tanabe, A., Nagatoishi, S., Tamura, Y., Matsuda, N., Liu, D., Hoang, Q. Q. & Tsumoto, K., 9 21 2018, : : ACS Chemical Biology. 13, 9, p. 2783-2793 11 p.

研究成果: ジャーナルへの寄稿記事

X Ray Crystallography
Oxidation-Reduction
Disease Progression
X ray crystallography
Assays
5 引用 (Scopus)

Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin

Kudo, S., Caaveiro, J. M. M., Nagatoishi, S., Miyafusa, T., Matsuura, T., Sudou, Y. & Tsumoto, K., 1 3 2017, : : Scientific reports. 7, 39518.

研究成果: ジャーナルへの寄稿記事

公開
Cadherins
Cell Adhesion
Adhesives
Antibodies
Therapeutic Uses
12 引用 (Scopus)
ATP-Dependent Proteases
Escherichia coli
Adenosine Triphosphatases
Genes
Mutation
26 引用 (Scopus)

Distribution and trafficking of MPR300 is normal in cells with cholesterol accumulated in late endocytic compartments: Evidence for early endosome-to-TGN trafficking of MPR300

Umeda, A., Fujita, H., Kuronita, T., Hirosako, K., Himeno, M. & Tanaka, Y., 10 1 2003, : : Journal of Lipid Research. 44, 10, p. 1821-1832 12 p.

研究成果: ジャーナルへの寄稿記事

trans-Golgi Network
Endosomes
Fibroblasts
Cholesterol
Lysosomes
10 引用 (Scopus)

Distribution of 14C-2,3,7,8-tetrachlorodibenzo-p-dioxin to the brain and peripheral tissues of fetal rats and its comparison with adults

Ishida, T., Matsumoto, Y., Takeda, T., Koga, T., Ishii, Y. & Yamada, H., 8 1 2010, : : Journal of Toxicological Sciences. 35, 4, p. 563-569 7 p.

研究成果: ジャーナルへの寄稿記事

Rats
Brain
Fetus
Tissue
Gonadotropins
57 引用 (Scopus)
Sphingolipid Activator Proteins
Saposins
Lysosomal Storage Diseases
Proteins
1 引用 (Scopus)

Distribution of Solasodine glycosides in solanum khasianum fruiting stage determined by ELISA and western blotting

Putalun, W., Tanaka, H., Ikenaka, T. & Shoyama, Y., 1 1 2001, : : Natural Medicines. 55, 5, p. 243-246 4 p.

研究成果: ジャーナルへの寄稿記事

Solanum
Glycosides
Fruits
Western Blotting
Enzyme-Linked Immunosorbent Assay
171 引用 (Scopus)

Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts

Eskelinen, E. L., Schmidt, C. K., Neu, S., Willenborg, M., Fuertes, G., Salvador, N., Tanaka, Y., Lüllmann-Rauch, R., Hartmann, D., Heeren, J., Von Figura, K., Knecht, E. & Saftig, P., 7 1 2004, : : Molecular biology of the cell. 15, 7, p. 3132-3145 14 p.

研究成果: ジャーナルへの寄稿記事

Autophagy
Fibroblasts
Cholesterol
Vacuoles
Proteolysis
68 引用 (Scopus)

Disulfide bond structure of human epidermal growth factor receptor

Abe, Y., Odaka, M., Inagaki, F., Lax, I., Schlessinger, J. & Kohda, D., 5 1 1998, : : Journal of Biological Chemistry. 273, 18, p. 11150-11157 8 p.

研究成果: ジャーナルへの寄稿記事

Epidermal Growth Factor Receptor
Disulfides
Cysteine
Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
Laminin
8 引用 (Scopus)

Diverse metabolites of coral reef organisms

Tanaka, J., Kuniyoshi, M., Tanaka, C., Issa, H. H., Balansa, W., Otsuka, M., Githige, W. P. & Higa, T., 1 1 2005, : : Pure and Applied Chemistry. 77, 1, p. 83-89 7 p.

研究成果: ジャーナルへの寄稿記事

Reefs
Metabolites
Polyacetylenes
Depsipeptides
Hydroquinones
57 引用 (Scopus)
Cell Cycle
Hydrolysis
Adenosine Triphosphate
Integration Host Factors
DNA Replication
16 引用 (Scopus)
DNA-Binding Proteins
Adenosine Triphosphate
Hydrolysis
Proteins
Adenosine Diphosphate
4 引用 (Scopus)

DnaA protein Lys-415 is close to the ATP-binding site: ATP-pyridoxal affinity labeling

Kubota, T., Ito, Y., Sekimizu, K., Tagaya, M. & Katayama, T., 11 16 2001, : : Biochemical and Biophysical Research Communications. 288, 5, p. 1141-1148 8 p.

研究成果: ジャーナルへの寄稿記事

Pyridoxal
Labeling
Adenosine Triphosphate
Binding Sites
Proteins

DnaAの制御的不活性化 (RIDA): 構成因子Hda・pol IIIクランプ複合体の精製ならびに性状解析

川上広宣, 10 25 2003, : : Genes and Genetic Systems. 78, 5, p. 5

研究成果: ジャーナルへの寄稿記事

16 引用 (Scopus)

DNA polymerase IV mediates efficient and quick recovery of replication forks stalled at N2-dG adducts

Ikeda, M., Furukohri, A., Philippin, G., Loechler, E., Akiyama, M. T., Katayama, T., Fuchs, R. P. & Maki, H., 2014, : : Nucleic acids research. 42, 13, p. 8461-8472 12 p.

研究成果: ジャーナルへの寄稿記事

DNA Polymerase beta
DNA
Escherichia coli
Benzo(a)pyrene
DNA-Directed DNA Polymerase
29 引用 (Scopus)

DNA replication-coupled inactivation of DnaA protein in vitro: A role for DnaA arginine-334 of the AAA+ Box VIII motif in ATP hydrolysis

Su'Etsugu, M., Kawakami, H., Kurokawa, K., Kubota, T., Takata, M. & Katayama, T., 5 12 2001, : : Molecular Microbiology. 40, 2, p. 376-386 11 p.

研究成果: ジャーナルへの寄稿記事

DNA Replication
Arginine
Hydrolysis
Adenosine Triphosphate
Proteins
1 引用 (Scopus)

DNA replication defects in a mutant deficient in the thioredoxin homolog YbbN

Le, H. T., Gautier, V., Kthiri, F., Kohiyama, M., Katayama, T. & Richarme, G., 2 4 2011, : : Biochemical and Biophysical Research Communications. 405, 1, p. 52-57 6 p.

研究成果: ジャーナルへの寄稿記事

Holoenzymes
Thioredoxins
Clamping devices
DNA-Directed DNA Polymerase
DNA Replication
6 引用 (Scopus)

Domain separation and characterization of PriC, a replication restart primosome factor in Escherichia coli

Aramaki, T., Abe, Y., Ohkuri, T., Mishima, T., Yamashita, S., Katayama, T. & Ueda, T., 9 1 2013, : : Genes to Cells. 18, 9, p. 723-732 10 p.

研究成果: ジャーナルへの寄稿記事

Single-Stranded DNA
Binding Sites
Escherichia coli
Basic Amino Acids
DNA
35 引用 (Scopus)

Dorisenones, cytotoxic spongian diterpenoids, from the nudibranch Chromodoris obsoleta

Miyamoto, T., Sakamoto, K., Arao, K., Komori, T., Higuchi, R. & Sasaki, T., 6 10 1996, : : Tetrahedron. 52, 24, p. 8187-8198 12 p.

研究成果: ジャーナルへの寄稿記事

Diterpenes
Mollusca
Military Personnel
X ray analysis
X-Rays
24 引用 (Scopus)

Double staining of ginsenosides by western blotting using anti-ginsenoside Rb1 and Rg1 monoclonal antibodies

Fukuda, N., Tanaka, H. & Shoyama, Y., 11 21 2001, : : Biological and Pharmaceutical Bulletin. 24, 10, p. 1157-1160 4 p.

研究成果: ジャーナルへの寄稿記事

Ginsenosides
Western Blotting
Monoclonal Antibodies
Staining and Labeling
Bovine Serum Albumin
32 引用 (Scopus)

Drug-induced phospholipidosis is caused by blockade of mannose 6-phosphate receptor-mediated targeting of lysosomal enzymes

Ikeda, K., Hirayama, M., Hirota, Y., Asa, E., Seki, J. & Tanaka, Y., 12 5 2008, : : Biochemical and Biophysical Research Communications. 377, 1, p. 268-274 7 p.

研究成果: ジャーナルへの寄稿記事

IGF Type 2 Receptor
Enzymes
Pharmaceutical Preparations
Phospholipids
Endosomes
19 引用 (Scopus)

Duloxetine inhibits microglial P2X4 receptor function and alleviates neuropathic pain after peripheral nerve injury

Yamashita, T., Yamamoto, S., Zhang, J., Kometani, M., Tomiyama, D., Kohno, K., Tozaki-Saitoh, H., Inoue, K. & Tsuda, M., 10 2016, : : PloS one. 11, 10, e0165189.

研究成果: ジャーナルへの寄稿記事

Purinergic P2X4 Receptors
Peripheral Nerve Injuries
peripheral nerves
Neuralgia
pain
18 引用 (Scopus)

Eastern blotting and immunoaffinity concentration using monoclonal antibody for ginseng saponins in the field of traditional Chinese medicines

Tanaka, H., Fukuda, N. & Shoyama, Y., 5 16 2007, : : Journal of Agricultural and Food Chemistry. 55, 10, p. 3783-3787 5 p.

研究成果: ジャーナルへの寄稿記事

Ginsenosides
Panax
Saponins
Chinese Traditional Medicine
saponins
9 引用 (Scopus)

Eastern blotting and use of anti-saikosaponin a monoclonal antibodies for detection of saikosaponins

Zhu, S. H., Morinaga, O., Shimokawa, S., Shon, T. K., Lee, S. C., Shoyama, Y. & Tanaka, H., 4 1 2007, : : Journal of Natural Medicines. 61, 2, p. 178-183 6 p.

研究成果: ジャーナルへの寄稿記事

Monoclonal Antibodies
Bovine Serum Albumin
Kampo Medicine
Quality Control
Quality control
27 引用 (Scopus)

Effective renaturation of denatured and reduced immunoglobulin G in vitro without assistance of chaperone

Maeda, Y., Ueda, T. & Imoto, T., 1 1 1996, : : Protein Engineering. 9, 1, p. 95-100 6 p.

研究成果: ジャーナルへの寄稿記事

Immunoglobulin G
Protein Refolding
Proteins
Agglomeration
Affinity chromatography
1 引用 (Scopus)

Effective renaturation of met-1 lysozyme expressed in Escherichia Coli as inclusion bodies

Maeda, Y., Ueda, T. & Imoto, T., 12 1 1998, : : Protein and Peptide Letters. 5, 2, p. 67-74 8 p.

研究成果: ジャーナルへの寄稿記事

Inclusion Bodies
Muramidase
Escherichia coli
Dialysis
Dilution
71 引用 (Scopus)

Effective renaturation of reduced lysozyme by gentle removal of urea

Maeda, Y., Koga, H., Yamada, H., Ueda, T. & Imoto, T., 2 1 1995, : : Protein Engineering, Design and Selection. 8, 2, p. 201-205 5 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Urea
Enzymes
Dialysis
Buffers
6 引用 (Scopus)

Effect of a coplanar PCB on lipid metabolism: the remarkable difference between rats and guinea pigs

Hatsumura, M., Ishida, T., Ishii, Y., Ariyoshi, N., Oguri, K. & Yoshimura, H., 1 1 1995, : : Fukuoka igaku zasshi = Hukuoka acta medica. 86, 5, p. 135-143 9 p.

研究成果: ジャーナルへの寄稿記事

Polychlorinated Biphenyls
Lipid Metabolism
Guinea Pigs
Control Groups
Triglycerides
78 引用 (Scopus)

Effect of additives on the renaturation of reduced lysozyme in the presence of 4 M urea

Maeda, Y., Yamada, H., Ueda, T. & Imoto, T., 5 1 1996, : : Protein Engineering. 9, 5, p. 461-465 5 p.

研究成果: ジャーナルへの寄稿記事

Muramidase
Urea
Enzymes
Freezing
Melting point
57 引用 (Scopus)

Effect of buffer species on the unfolding and the aggregation of humanized IgG

Kameoka, D., Masuzaki, E., Ueda, T. & Imoto, T., 9 1 2007, : : Journal of Biochemistry. 142, 3, p. 383-391 9 p.

研究成果: ジャーナルへの寄稿記事

Buffers
Agglomeration
Immunoglobulin G
Morpholinos
Hot Temperature
21 引用 (Scopus)

Effect of chemical modifications of tryptophan residues on the folding of reduced hen egg-white lysozyme

Ueda, T., Yamada, H., Aoki, H. & Imoto, T., 1 1 1990, : : Journal of Biochemistry. 108, 5, p. 886-892 7 p.

研究成果: ジャーナルへの寄稿記事

Egg White
Chemical modification
Muramidase
Tryptophan
hen egg lysozyme

Effect of coplanar PCB on gluconeogenesis and lipid metabolism: Comparison between rats and guinea pigs

Hatsumura, M., Ishida, T., Ishii, Y., Ariyoshi, N., Koga, Y., Oguri, K. & Yoshimura, H., 1 1 1994, : : Japanese Journal of Toxicology and Environmental Health. 40, 1, p. P27

研究成果: ジャーナルへの寄稿記事

Gluconeogenesis
Polychlorinated Biphenyls
Lipid Metabolism
Guinea Pigs
2 引用 (Scopus)

Effect of Cynaropicrin on 2,3,4,7,8-Pentachlorodibenzofuran-induced Wasting Syndrome and Oxidative Stress

Yamada, K. I., Ishii, Y., Takeda, T., Kuroki, H., Mitoma, C., Hiroshi, U., Furue, M. & Yamada, H., 5 1 2015, : : Fukuoka igaku zasshi = Hukuoka acta medica. 106, 5, p. 169-175 7 p.

研究成果: ジャーナルへの寄稿記事

Wasting Syndrome
Oxidative Stress
Cynara scolymus
cynaropicrin
2,3,4,7,8-pentachlorodibenzofuran
6 引用 (Scopus)

Effect of CYP2A6 genetic polymorphism on the metabolic conversion of tegafur to 5-fluorouracil and its enantioselectivity

Yamamiya, I., Yoshisue, K., Ishii, Y., Yamada, H. & Chiba, M., 9 2014, : : Drug Metabolism and Disposition. 42, 9, p. 1485-1492 8 p.

研究成果: ジャーナルへの寄稿記事

Tegafur
Genetic Polymorphisms
Fluorouracil
Enzymes
Amino Acid Substitution
1 引用 (Scopus)

Effect of Dioxins on Molecular Chaperones HSP70 and HSP90 in Rat Leydig Cells

Fukuda, A., Kurogi, R., Tasaki, K., Ishida, T., Ishii, Y. & Oguri, K., 1 1 1999, : : Journal of Health Science. 45, 1, 1 p.

研究成果: ジャーナルへの寄稿記事

Molecular Chaperones
Dioxins
Rats
122 引用 (Scopus)

Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4

Ohnishi, A., Matsuo, H., Yamada, S., Takanaga, H., Morimoto, S., Shoyama, Y., Ohtani, H. & Sawada, Y., 1 1 2000, : : British Journal of Pharmacology. 130, 6, p. 1369-1377 9 p.

研究成果: ジャーナルへの寄稿記事

Citrus paradisi
Cytochrome P-450 CYP3A
Caco-2 Cells
Vinblastine
P-Glycoprotein
6 引用 (Scopus)

Effect of glycyrrhetinic acid on lipid raft model at the air/water interface

Sakamoto, S., Uto, T. & Shoyama, Y., 1 1 2015, : : Biochimica et Biophysica Acta - Biomembranes. 1848, 2, p. 434-443 10 p.

研究成果: ジャーナルへの寄稿記事

Glycyrrhetinic Acid
Air
Glycyrrhizic Acid
Lipids
Water