トランスオミクス医学研究センター

研究成果

Dietary Intake of Curcumin Improves eIF2 Signaling and Reduces Lipid Levels in the White Adipose Tissue of Obese Mice

Kobori, M., Takahashi, Y., Takeda, H., Takahashi, M., Izumi, Y., Akimoto, Y., Sakurai, M., Oike, H., Nakagawa, T., Itoh, M., Bamba, T. & Kimura, T., 12 1 2018, : : Scientific reports. 8, 1, 9081.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells

Shishido, Y., Baba, T., Sato, T., Shima, Y., Miyabayashi, K., Inoue, M., Akiyama, H., Kimura, H., Kanai, Y., Ishihara, Y., Haraguchi, S., Miyazaki, A., Rozman, D., Yamazaki, T., Choi, M. H., Ohkawa, Y., Suyama, M. & Morohashi, K. I., 1 1 2017, : : Scientific reports. 7, 41912.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

Direct isolation and RNA-seq reveal environment-dependent properties of engrafted neural stem/progenitor cells

Kumamaru, H., Ohkawa, Y., Saiwai, H., Yamada, H., Kubota, K., Kobayakawa, K., Akashi, K., Okano, H., Iwamoto, Y. & Okada, S., 11 26 2012, : : Nature communications. 3, 1140.

研究成果: ジャーナルへの寄稿記事

41 引用 (Scopus)

Direct isopropanol production from cellobiose by engineered Escherichia coli using a synthetic pathway and a cell surface display system

Soma, Y., Inokuma, K., Tanaka, T., Ogino, C., Kondo, A., Okamoto, M. & Hanai, T., 7 1 2012, : : Journal of Bioscience and Bioengineering. 114, 1, p. 80-85 6 p.

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)

Direct reprogramming of spiral ganglion non-neuronal cells into neurons: Toward ameliorating sensorineural hearing loss by gene therapy

Noda, T., Meas, S. J., Nogami, J., Amemiya, Y., Uchi, R., Ohkawa, Y., Nishimura, K. & Dabdoub, A., 2 14 2018, : : Frontiers in Cell and Developmental Biology. 6, FEB, 16.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Distinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status

Sakanaka, A., Kuboniwa, M., Hashino, E., Bamba, T., Fukusaki, E. & Amano, A., 2 21 2017, : : Scientific reports. 7, 42818.

研究成果: ジャーナルへの寄稿記事

14 引用 (Scopus)

Distribution of histone H4 modifications as revealed by a panel of specific monoclonal antibodies

Hayashi-Takanaka, Y., Maehara, K., Harada, A., Umehara, T., Yokoyama, S., Obuse, C., Ohkawa, Y., Nozaki, N. & Kimura, H., 12 1 2015, : : Chromosome Research. 23, 4, p. 753-766 14 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

Diversity in the matrix structure of eggshells in the testudines (reptilia)

Kusuda, S., Yasukawa, Y., Shibata, H., Saito, T., Doi, O., Ohya, Y. & Yoshizaki, N., 5 1 2013, : : Zoological science. 30, 5, p. 366-374 9 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

Dmrt factors determine the positional information of cerebral cortical progenitors via differential suppression of homeobox genes

Konno, D., Kishida, C., Maehara, K., Ohkawa, Y., Kiyonari, H., Okada, S. & Matsuzaki, F., 8 2019, : : Development (Cambridge). 146, 15, dev174243.

研究成果: ジャーナルへの寄稿記事

公開
1 引用 (Scopus)

DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testis

Kubo, N., Toh, H., Shirane, K., Shirakawa, T., Kobayashi, H., Sato, T., Sone, H., Sato, Y., Tomizawa, S. I., Tsurusaki, Y., Shibata, H., Saitsu, H., Suzuki, Y., Matsumoto, N., Suyama, M., Kono, T., Ohbo, K. & Sasaki, H., 8 20 2015, : : BMC Genomics. 16, 1, 624.

研究成果: ジャーナルへの寄稿記事

52 引用 (Scopus)

DNA methylation of the Klf14 gene region in whole blood cells provides prediction for the chronic inflammation in the adipose tissue

Iwaya, C., Kitajima, H., Yamamoto, K., Maeda, Y., Sonoda, N., Shibata, H. & Inoguchi, T., 3 11 2018, : : Biochemical and Biophysical Research Communications. 497, 3, p. 908-915 8 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Does ossification of the posterior longitudinal ligament affect the neurological outcome after traumatic cervical cord injury?

Okada, S., Maeda, T., Ohkawa, Y., Harimaya, K., Saiwai, H., Kumamaru, H., Matsumoto, Y., Doi, T., Ueta, T., Shiba, K. & Iwamoto, Y., 5 15 2009, : : Spine. 34, 11, p. 1148-1152 5 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

Drosophila sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity

Rahman, M., Nirala, N. K., Singh, A., Zhu, L. J., Taguchi, K., Bamba, T., Fukusaki, E., Shaw, L. M., Lambright, D. G., Acharya, J. K. & Acharya, U. R., 2014, : : Journal of Cell Biology. 206, 2, p. 289-305 17 p.

研究成果: ジャーナルへの寄稿記事

49 引用 (Scopus)

Dynamic regulation of ubiquitylation and deubiquitylation at the central spindle during cytokinesis

Mukai, A., Mizuno, E., Kobayashi, K., Matsumoto, M., Nakayama, K. I., Kitamura, N. & Komada, M., 4 15 2008, : : Journal of Cell Science. 121, 8, p. 1325-1333 9 p.

研究成果: ジャーナルへの寄稿記事

35 引用 (Scopus)

Effect of Furan Fatty Acids and 3-Methyl-2,4-nonanedione on Light-Induced Off-Odor in Soybean Oil

Sano, T., Okabe, R., Iwahashi, M., Imagi, J., Sato, T., Yamashita, T., Fukusaki, E. & Bamba, T., 3 15 2017, : : Journal of Agricultural and Food Chemistry. 65, 10, p. 2136-2140 5 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Engrafted Neural Stem/Progenitor Cells Promote Functional Recovery through Synapse Reorganization with Spared Host Neurons after Spinal Cord Injury

Yokota, K., Kobayakawa, K., Kubota, K., Miyawaki, A., Okano, H., Ohkawa, Y., Iwamoto, Y. & Okada, S., 1 1 2015, : : Stem Cell Reports. 5, 2, p. 264-277 14 p.

研究成果: ジャーナルへの寄稿記事

30 引用 (Scopus)
1 引用 (Scopus)

Erratum: New Insight into the Role of the Calvin Cycle: Reutilization of CO2 Emitted through Sugar Degradation (Scientific Reports 5 (2016) (11617) DOI: 10.1038/srep11617)

Shimizu, R., Dempo, Y., Nakayama, Y., Nakamura, S., Bamba, T., Fukusaki, E. & Fukui, T., 6 20 2016, : : Scientific reports. 6, 27961.

研究成果: ジャーナルへの寄稿コメント/討論

1 引用 (Scopus)

Erratum: Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding (Immunity (2018) 48(6) (1119–1134.e7), (S1074761318301936) (10.1016/j.immuni.2018.04.024))

Hosokawa, H., Ungerbäck, J., Wang, X., Matsumoto, M., Nakayama, K. I., Cohen, S. M., Tanaka, T. & Rothenberg, E. V., 10 16 2018, : : Immunity. 49, 4, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

1 引用 (Scopus)

Erratum: Heterochromatin dynamics during the differentiation process revealed by the DNA methylation reporter mouse, MethylRO (Stem Cell Reports (2014) 2 (910-924))

Ueda, J., Maehara, K., Mashiko, D., Ichinose, T., Yao, T., Hori, M., Sato, Y., Kimura, H., Ohkawa, Y. & Yamagata, K., 7 8 2014, : : Stem Cell Reports. 3, 1, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Erratum: PSMC5, a 19S proteasomal ATPase, regulates cocaine action in the nucleus accumbens (PLoS ONE (2015) 10:5 (e0126710) DOI: 10.1371/journal.pone.0126710)

Ohnishi, Y. H., Ohnishi, Y. N., Nakamura, T., Ohno, M., Kennedy, P. J., Ohkawa, Y., Nishi, A., Neve, R., Tsuzuki, T. & Nestler, E. J., 6 25 2015, : : PloS one. 10, 6, e0131263.

研究成果: ジャーナルへの寄稿コメント/討論

Erratum: Structure and function of human histone H3.Y nucleosome (Nucleic acids research (2016) 44 13 (6127-6141))

Kujirai, T., Horikoshi, N., Sato, K., Maehara, K., Machida, S., Osakabe, A., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 7 2017, : : Nucleic acids research. 45, 6, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

1 引用 (Scopus)

Erratum: A novel protein with RNA-binding motifs interacts with ataxin-2 (Human Molecular Genetics (2000) vol.9 (1303-1313))

Shibata, H., Huynh, D. P. & Pulst, S. M., 8 17 2000, : : Human Molecular Genetics. 9, 12, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Establishment of neutralizing rat monoclonal antibodies for fibroblast growth factor-2

Tanaka, M., Yamaguchi, M., Shiota, M., Kawamoto, Y., Takahashi, K., Inagaki, A., Osada-Oka, M., Harada, A., Wanibuchi, H., Izumi, Y., Miura, K., Iwao, H. & Ohkawa, Y., 8 1 2014, : : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33, 4, p. 261-269 9 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Evolutionary relationships and sequence variation of α-amylase variants encoded by duplicated genes in the Amy locus of Drosophila melanogaster

Inomata, N., Shibata, H., Okuyama, E. & Yamazaki, T., 1 1 1995, : : Genetics. 141, 1, p. 237-244 8 p.

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

Evolution of the sperm methylome of primates is associated with retrotransposon insertions and genome instability

Fukuda, K., Inoguchi, Y., Ichiyanagi, K., Ichiyanagi, T., Go, Y., Nagano, M., Yanagawa, Y., Takaesu, N., Ohkawa, Y., Imai, H. & Sasaki, H., 9 2017, : : Human Molecular Genetics. 26, 18, p. 3508-3519 12 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Exploration of nucleosome positioning patterns in transcription factor function

Maehara, K. & Ohkawa, Y., 1 21 2016, : : Scientific reports. 6, 19620.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Facultative parthenogenesis validated by DNA analyses in the green anaconda (Eunectes murinus)

Shibata, H., Sakata, S., Hirano, Y., Nitasaka, E. & Sakabe, A., 12 2017, : : PloS one. 12, 12, e0189654.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)
17 引用 (Scopus)

Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development

Kitagawa, K., Shibat, K., Matsumoto, A., Matsumoto, M., Ohhata, T., Nakayama, K. I., Niida, H. & Kitagawa, M., 7 2014, : : Molecular and cellular biology. 34, 14, p. 2732-2744 13 p.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes

Hirano, A., Yumimoto, K., Tsunematsu, R., Matsumoto, M., Oyama, M., Kozuka-Hata, H., Nakagawa, T., Lanjakornsiripan, D., Nakayama, K. I. & Fukada, Y., 2 28 2013, : : Cell. 152, 5, p. 1106-1118 13 p.

研究成果: ジャーナルへの寄稿記事

126 引用 (Scopus)

Fbxo45, a novel ubiquitin ligase, regulates synaptic activity

Tada, H., Okano, H. J., Takagi, H., Shibata, S., Yao, I., Matsumoto, M., Saiga, T., Nakayama, K. I., Kashima, H., Takahashi, T., Setou, M. & Okano, H., 2 5 2010, : : Journal of Biological Chemistry. 285, 6, p. 3840-3849 10 p.

研究成果: ジャーナルへの寄稿記事

46 引用 (Scopus)

Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development

Saiga, T., Fukuda, T., Matsumoto, M., Tada, H., Okano, H. J., Okano, H. & Nakayama, K. I., 7 1 2009, : : Molecular and cellular biology. 29, 13, p. 3529-3543 15 p.

研究成果: ジャーナルへの寄稿記事

66 引用 (Scopus)

Fetal leydig cells dedifferentiate and serve as adult leydig stem cells

Shima, Y., Miyabayashi, K., Sato, T., Suyama, M., Ohkawa, Y., Doi, M., Okamura, H. & Suzuki, K., 12 2018, : : Development (Cambridge). 145, 23, dev169136.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Flow cytometric sorting of neuronal and glial nuclei from central nervous system tissue

Okada, S., Saiwai, H., Kumamaru, H., Kubota, K., Harada, A., Yamaguchi, M., Iwamoto, Y. & Ohkawa, Y., 2 1 2011, : : Journal of cellular physiology. 226, 2, p. 552-558 7 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

Foxl3 is a germ cell-intrinsic factor involved in sperm-egg fate decision in medaka

Nishimura, T., Sato, T., Yamamoto, Y., Watakabe, I., Ohkawa, Y., Suyama, M., Kobayashi, S. & Tanaka, M., 7 17 2015, : : Science. 349, 6245, p. 328-331 4 p.

研究成果: ジャーナルへの寄稿記事

46 引用 (Scopus)

Frequent Detection of Pituitary-Derived PrPres in Human Prion Diseases

Honda, H., Matsumoto, M., Shijo, M., Hamasaki, H., Sadashima, S., Suzuki, S. O., Aishima, S., Kai, K., Nakayama, K. I., Sasagasako, N. & Iwaki, T., 10 1 2019, : : Journal of neuropathology and experimental neurology. 78, 10, p. 922-929 8 p.

研究成果: ジャーナルへの寄稿記事

Functional analyses of the activation loop of phototropin2 in Arabidopsis

Inoue, S. I., Matsushita, T., Tomokiyo, Y., Matsumoto, M., Nakayama, K. I., Kinoshita, T. & Shimazaki, K. I., 5 1 2011, : : Plant physiology. 156, 1, p. 117-128 12 p.

研究成果: ジャーナルへの寄稿記事

52 引用 (Scopus)
49 引用 (Scopus)

Gas chromatography-mass spectrometry metabolomics-based prediction of potato tuber sprouting during long-term storage

Fukuda, T., Takamatsu, K., Bamba, T. & Fukusaki, E., 8 1 2019, : : Journal of Bioscience and Bioengineering. 128, 2, p. 249-254 6 p.

研究成果: ジャーナルへの寄稿記事

GC/MS based metabolomics: Development of a data mining system for metabolite identification by using soft independent modeling of class analogy (SIMCA)

Tsugawa, H., Tsujimoto, Y., Arita, M., Bamba, T. & Fukusaki, E., 5 4 2011, : : BMC bioinformatics. 12, 131.

研究成果: ジャーナルへの寄稿記事

121 引用 (Scopus)

Generation of a monoclonal antibody for INI1/hSNF5/BAF47

Harada, A., Hayashi, M., Kuniyoshi, Y., Semba, Y., Sugahara, S., Tachibana, T., Ohkawa, Y. & Fujita, M., 2 1 2014, : : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33, 1, p. 49-51 3 p.

研究成果: ジャーナルへの寄稿記事

Generation of a rat monoclonal antibody specific for Brm

Okada, S., Harada, A., Saiwai, H., Nakamura, M. & Ohkawa, Y., 12 1 2009, : : Hybridoma. 28, 6, p. 455-458 4 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Generation of a rat monoclonal antibody specific for Chd2

Harada, A., Yoshimura, S., Odawara, J., Azuma, M., Okada, S., Nakamura, M., Tachibana, T. & Ohkawa, Y., 4 1 2010, : : Hybridoma. 29, 2, p. 173-177 5 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Generation of a rat monoclonal antibody specific for heat shock cognate protein 70

Shiota, M., Saiwai, H., Mun, S., Harada, A., Okada, S., Odawara, J., Tanaka, M., Iwao, H. & Ohkawa, Y., 10 1 2010, : : Hybridoma. 29, 5, p. 453-456 4 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Generation of a rat monoclonal antibody specific for Hsp72

Tanaka, M., Shiota, M., Okada, S., Harada, A., Odawara, J., Mun, S., Iwao, H. & Ohkawa, Y., 8 1 2011, : : Hybridoma. 30, 4, p. 397-400 4 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Generation of a rat monoclonal antibody specific for Pax7

Harada, A., Okada, S., Saiwai, H., Aoki, M., Nakamura, M. & Ohkawa, Y., 12 1 2009, : : Hybridoma. 28, 6, p. 451-453 3 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Genetic reevaluation of the Role of F-Box proteins in cyclin D1 degradation

Kanie, T., Onoyama, I., Matsumoto, A., Yamada, M., Nakatsumi, H., Tateishi, Y., Yamamura, S., Tsunematsu, R., Matsumoto, M. & Nakayama, K. I., 2 1 2012, : : Molecular and cellular biology. 32, 3, p. 590-605 16 p.

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

Genome-wide analysis of histone modifications in human endometrial stromal cells

Tamura, I., Ohkawa, Y., Sato, T., Suyama, M., Jozaki, K., Okada, M., Lee, L., Maekawa, R., Asada, H., Sato, S., Yamagata, Y., Tamura, H. & Sugino, N., 10 1 2014, : : Molecular Endocrinology. 28, 10, p. 1656-1669 14 p.

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)