トランスオミクス医学研究センター

研究成果

記事

Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages

Nakatsumi, H., Matsumoto, M. & Nakayama, K. I., 11 28 2017, : : Cell Reports. 21, 9, p. 2471-2486 16 p.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36

Endo, A., Matsumoto, M., Inada, T., Yamamoto, A., Nakayama, K. I., Kitamura, N. & Komada, M., 3 1 2009, : : Journal of cell science. 122, 5, p. 678-686 9 p.

研究成果: ジャーナルへの寄稿記事

45 引用 (Scopus)

Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme

Nasipak, B. T., Padilla-Benavides, T., Green, K. M., Leszyk, J. D., Mao, W., Konda, S., Sif, S., Shaffer, S. A., Ohkawa, Y. & Imbalzano, A. N., 6 17 2015, : : Nature communications. 6, 7441.

研究成果: ジャーナルへの寄稿記事

12 引用 (Scopus)

Ossification of the posterior longitudinal ligament of the lumbar spine: A case series

Okada, S., Maeda, T., Saiwai, H., Ohkawa, Y., Shiba, K. & Iwamoto, Y., 11 1 2010, : : Neurosurgery. 67, 5, p. 1311-1318 8 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Overexpression of Ephrin A2 receptors in cancer stromal cells is a prognostic factor for the relapse of gastric cancer

Kikuchi, S., Kaibe, N., Morimoto, K., Fukui, H., Niwa, H., Maeyama, Y., Takemura, M., Matsumoto, M., Nakamori, S., Miwa, H., Hirota, S. & Sasako, M., 7 27 2015, : : Gastric Cancer. 18, 3, p. 485-494 10 p.

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

Partial SPAST and DPY30 deletions in a Japanese spastic paraplegia type 4 family

Miura, S., Shibata, H., Kida, H., Noda, K., Toyama, T., Iwasaki, N., Iwaki, A., Ayabe, M., Aizawa, H., Taniwaki, T. & Fukumaki, Y., 2 1 2011, : : Neurogenetics. 12, 1, p. 25-31 7 p.

研究成果: ジャーナルへの寄稿記事

10 引用 (Scopus)

Pathological changes of distal motor neurons after complete spinal cord injury

Yokota, K., Kubota, K., Kobayakawa, K., Saito, T., Hara, M., Kijima, K., Maeda, T., Katoh, H., Ohkawa, Y., Nakashima, Y. & Okada, S., 1 9 2019, : : Molecular Brain. 12, 1, 4.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Performance of small-domain monolithic silica columns in nano-liquid chromatography and comparison with commercial packed bed columns with 2 µm particles

Hara, T., Izumi, Y., Hata, K., V. Baron, G., Bamba, T. & Desmet, G., 1 1 2020, (受理済み/印刷中) : : Journal of Chromatography A. 460804.

研究成果: ジャーナルへの寄稿記事

Periostin Promotes Scar Formation through the Interaction between Pericytes and Infiltrating Monocytes/Macrophages after Spinal Cord Injury

Yokota, K., Kobayakawa, K., Saito, T., Hara, M., Kijima, K., Ohkawa, Y., Harada, A., Okazaki, K., Ishihara, K., Yoshida, S., Kudo, A., Iwamoto, Y. & Okada, S., 3 1 2017, : : American Journal of Pathology. 187, 3, p. 639-653 15 p.

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

Persistent detection of alternatively spliced BCR-ABL variant results in a failure to achieve deep molecular response

Yuda, J., Miyamoto, T., Odawara, J., Ohkawa, Y., Semba, Y., Hayashi, M., Miyamura, K., Tanimoto, M., Yamamoto, K., Taniwaki, M. & Akashi, K., 11 2017, : : Cancer Science. 108, 11, p. 2204-2212 9 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Phosphoproteomics analyses show subnetwork systems in T-cell receptor signaling

Hatano, A., Matsumoto, M. & Nakayama, K. I., 10 1 2016, : : Genes to Cells. 21, 10, p. 1095-1112 18 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Phosphorylation of Noxo1 at threonine 341 regulates its interaction with Noxa1 and the superoxide-producing activity of Nox1

Yamamoto, A., Takeya, R., Matsumoto, M., Nakayama, K. & Sumimoto, H., 10 1 2013, : : FEBS Journal. 280, 20, p. 5145-5159 15 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

Phosphorylation of the chromodomain changes the binding specificity of Cbx2 for methylated histone H3

Hatano, A., Matsumoto, M., Higashinakagawa, T. & Nakayama, K. I., 6 18 2010, : : Biochemical and Biophysical Research Communications. 397, 1, p. 93-99 7 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth

Morita, M., Sato, T., Nomura, M., Sakamoto, Y., Inoue, Y., Tanaka, R., Ito, S., Kurosawa, K., Yamaguchi, K., Sugiura, Y., Takizaki, H., Yamashita, Y., Katakura, R., Sato, I., Kawai, M., Okada, Y., Watanabe, H., Kondoh, G., Matsumoto, S., Kishimoto, A. および12人, Obata, M., Matsumoto, M., Fukuhara, T., Motohashi, H., Suematsu, M., Komatsu, M., Nakayama, K. I., Watanabe, T., Soga, T., Shima, H., Maemondo, M. & Tanuma, N., 3 12 2018, : : Cancer Cell. 33, 3, p. 355-367.e7

研究成果: ジャーナルへの寄稿記事

28 引用 (Scopus)

Plasma gelsolin facilitates interaction between β2 glycoprotein I and α5β1 integrin

Bohgaki, M., Matsumoto, M., Atsumi, T., Kondo, T., Yasuda, S., Horita, T., Nakayama, K. I., Okumura, F., Hatakeyama, S. & Koike, T., 1 1 2011, : : Journal of Cellular and Molecular Medicine. 15, 1, p. 141-151 11 p.

研究成果: ジャーナルへの寄稿記事

16 引用 (Scopus)

Polymorphism analysis of the upstream region of the human N-methyl-D-aspartate receptor subunit NR1 gene (GRIN1): Implications for schizophrenia

Tani, A., Kikuta, R., Itoh, K., Joo, A., Shibata, H., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 11 1 2002, : : Schizophrenia research. 58, 1, p. 83-86 4 p.

研究成果: ジャーナルへの寄稿記事

19 引用 (Scopus)

Positive association of Phencyclidine-responsive genes, PDE4A and PLAT, with schizophrenia

Deng, X., Takaki, H., Wang, L., Kuroki, T., Nakahara, T., Hashimoto, K., Ninomiya, H., Arinami, T., Inada, T., Ujike, H., Itokawa, M., Tochigi, M., Watanabe, Y., Someya, T., Kunugi, H., Iwata, N., Ozaki, N., Shibata, H. & Fukumaki, Y., 12 1 2011, : : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 156, 7, p. 850-858 9 p.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

Positive association of the AMPA receptor subunit GluR4 gene (GRIA4) haplotype with schizophrenia: Linkage disequilibrium mapping using SNPs evenly distributed across the gene region

Makino, C., Fujii, Y., Kikuta, R., Hirata, N., Tani, A., Shibata, A., Ninomiya, H., Tashiro, N., Shibata, H. & Fukumaki, Y., 1 1 2003, : : American Journal of Medical Genetics - Neuropsychiatric Genetics. 116 B, 1, p. 17-22 6 p.

研究成果: ジャーナルへの寄稿記事

47 引用 (Scopus)

Positive associations of polymorphisms in the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia

Fujii, Y., Shibata, H., Kikuta, R., Makino, C., Tani, A., Hirata, N., Shibata, A., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 6 2003, : : Psychiatric Genetics. 13, 2, p. 71-76 6 p.

研究成果: ジャーナルへの寄稿記事

99 引用 (Scopus)

Positive associations of polymorphisms in the metabotropic glutamate receptor type 8 gene (GRM8) with schizophrenia

Takaki, H., Kikuta, R., Shibata, H., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 7 1 2004, : : American Journal of Medical Genetics - Neuropsychiatric Genetics. 128 B, 1, p. 6-14 9 p.

研究成果: ジャーナルへの寄稿記事

42 引用 (Scopus)

Prediction of periodontal inflammation via metabolic profiling of saliva

Kuboniwa, M., Sakanaka, A., Hashino, E., Bamba, T., Fukusaki, E. & Amano, A., 11 1 2016, : : Journal of Dental Research. 95, 12, p. 1381-1386 6 p.

研究成果: ジャーナルへの寄稿記事

20 引用 (Scopus)

Preferential interaction of TIP120A with Cul1 that is not modified by NEDD8 and not associated with Skp1

Oshikawa, K., Matsumoto, M., Yada, M., Kamura, T., Hatakeyama, S. & Nakayama, K. I., 4 18 2003, : : Biochemical and Biophysical Research Communications. 303, 4, p. 1209-1216 8 p.

研究成果: ジャーナルへの寄稿記事

52 引用 (Scopus)

Production of a rat monoclonal antibody against Brg1

Ohkawa, Y., Harada, A., Nakamura, M., Yoshimura, S. & Tachibana, T., 12 1 2009, : : Hybridoma. 28, 6, p. 463-466 4 p.

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

Production of a rat monoclonal antibody specific for Myf5

Harada, A., Okada, S., Odawara, J., Kumamaru, H., Saiwai, H., Aoki, M., Nakamura, M., Nishiyama, Y. & Ohkawa, Y., 2 1 2010, : : Hybridoma. 29, 1, p. 59-62 4 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Production of BBF2H7-derived small peptide fragments via endoplasmic reticulum stress-dependent regulated intramembrane proteolysis

Matsuhisa, K., Saito, A., Cai, L., Kaneko, M., Okamoto, T., Sakaue, F., Asada, R., Urano, F., Yanagida, K., Okochi, M., Kudo, Y., Matsumoto, M., Nakayama, K. I. & Imaizumi, K., 1 1 2020, : : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 1, p. 865-880 16 p.

研究成果: ジャーナルへの寄稿記事

公開

Production of Eucommia-rubber from Eucommia ulmoides Oliv. (Hardy Rubber Tree)

Nakazawa, Y., Bamba, T., Takeda, T., Uefuji, H., Harada, Y., Li, X., Chen, R., Inoue, S., Tutumi, M., Shimizu, T., Su, Y. Q., Gyokusen, K., Fukusaki, E. & Kobayashi, A., 2009, : : Plant Biotechnology. 26, 1, p. 71-79 9 p.

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)
5 引用 (Scopus)

Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors

Takashima, Y., Horisawa, K., Udono, M., Ohkawa, Y. & Suzuki, A., 11 1 2018, : : Cancer Science. 109, 11, p. 3543-3553 11 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Protection of stromal cell-derived factor 2 by heat shock protein 72 prevents oxaliplatin-induced cell death in oxaliplatin-resistant human gastric cancer cells

Takahashi, K., Tanaka, M., Yashiro, M., Matsumoto, M., Ohtsuka, A., Nakayama, K. I., Izumi, Y., Nagayama, K., Miura, K., Iwao, H. & Shiota, M., 8 1 2016, : : Cancer Letters. 378, 1, p. 8-15 8 p.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

Proteome of ubiquitin/MVB pathway: Possible involvement of iron-induced ubiquitylation of transferrin receptor in lysosomal degradation

Tachiyama, R., Ishikawa, D., Matsumoto, M., Nakayama, K. I., Yoshimori, T., Yokota, S., Himeno, M., Tanaka, Y. & Fujita, H., 4 1 2011, : : Genes to Cells. 16, 4, p. 448-466 19 p.

研究成果: ジャーナルへの寄稿記事

16 引用 (Scopus)

Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin

Oshikawa, K., Matsumoto, M., Oyamada, K. & Nakayama, K. I., 2 3 2012, : : Journal of Proteome Research. 11, 2, p. 796-807 12 p.

研究成果: ジャーナルへの寄稿記事

27 引用 (Scopus)
71 引用 (Scopus)

Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia

Hashimoto, Y., Shirane, M., Matsuzaki, F., Saita, S., Ohnishi, T. & Nakayama, K. I., 1 1 2014, : : Journal of Biological Chemistry. 289, 19, p. 12946-12961 16 p.

研究成果: ジャーナルへの寄稿記事

26 引用 (Scopus)
50 引用 (Scopus)

PSMC5, a 19S proteasomal ATPase, regulates cocaine action in the nucleus accumbens

Ohnishi, Y. H., Ohnishi, Y. N., Nakamura, T., Ohno, M., Kennedy, P. J., Yasuyuki, O., Nishi, A., Neve, R., Tsuzuki, T. & Nestler, E. J., 5 11 2015, : : PloS one. 10, 5, e0126710.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Purification, primary structures and evolution of coagulant proteases from Deinagkistrodon actus venom

Nikandrov, N. N., Deshimaru, M., Tani, A., Chijiwa, T., Shibata, H., Chang, C. C., Fukumaki, Y., Ito, T. & Ohno, M., 12 15 2005, : : Toxicon. 46, 8, p. 907-917 11 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Quality evaluation of green tea leaf cultured under artificial light condition using gas chromatography/mass spectrometry

Miyauchi, S., Yonetani, T., Yuki, T., Tomio, A., Bamba, T. & Fukusaki, E., 2 1 2017, : : Journal of Bioscience and Bioengineering. 123, 2, p. 197-202 6 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Quantification of coffee blends for authentication of Asian palm civet coffee (Kopi Luwak) via metabolomics: A proof of concept

Jumhawan, U., Putri, S. P., Yusianto, Bamba, T. & Fukusaki, E., 7 1 2016, : : Journal of Bioscience and Bioengineering. 122, 1, p. 79-84 6 p.

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

Quantitative target analysis and kinetic profiling of acyl-CoAs reveal the rate-limiting step in cyanobacterial 1-butanol production

Noguchi, S., Putri, S. P., Lan, E. I., Laviña, W. A., Dempo, Y., Bamba, T., Liao, J. C. & Fukusaki, E., 2 1 2016, : : Metabolomics. 12, 2, p. 1-10 10 p., 26.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

Rat monoclonal antibody specific for MyoD

Harada, A., Ohkawa, Y., Ao, S., Odawara, J., Okada, S., Azuma, M., Nishiyama, Y., Nakamura, M. & Tachibana, T., 6 1 2010, : : Hybridoma. 29, 3, p. 255-258 4 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Rat monoclonal antibody specific for the chromatin remodeling factor, CHD1

Yoshimura, S., Harada, A., Odawara, J., Azuma, M., Okada, S., Nakamura, M., Ohkawa, Y. & Tachibana, T., 6 1 2010, : : Hybridoma. 29, 3, p. 237-240 4 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)
10 引用 (Scopus)

Reconstruction of global regulatory network from signaling to cellular functions using phosphoproteomic data

Kawata, K., Yugi, K., Hatano, A., Kokaji, T., Tomizawa, Y., Fujii, M., Uda, S., Kubota, H., Matsumoto, M., Nakayama, K. I. & Kuroda, S., 1 2019, : : Genes to Cells. 24, 1, p. 82-93 12 p.

研究成果: ジャーナルへの寄稿記事

Reconstruction of insulin signal flow from phosphoproteome and metabolome data

Yugi, K., Kubota, H., Toyoshima, Y., Noguchi, R., Kawata, K., Komori, Y., Uda, S., Kunida, K., Tomizawa, Y., Funato, Y., Miki, H., Matsumoto, M., Nakayama, K. I., Kashikura, K., Endo, K., Ikeda, K., Soga, T. & Kuroda, S., 8 21 2014, : : Cell Reports. 8, 4, p. 1171-1183 13 p.

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)

Regulation of ectopic heterochromatin-mediated epigenetic diversification by the JmjC family protein Epe1

Sorida, M., Hirauchi, T., Ishizaki, H., Kaito, W., Shimada, A., Mori, C., Chikashige, Y., Hiraoka, Y., Suzuki, Y., Ohkawa, Y., Kato, H., Takahata, S. & Murakami, Y., 6 2019, : : PLoS genetics. 15, 6, e1008129.

研究成果: ジャーナルへの寄稿記事

公開
1 引用 (Scopus)

Regulation of RNA polymerase II activation by histone acetylation in single living cells

Stasevich, T. J., Hayashi-Takanaka, Y., Sato, Y., Maehara, K., Ohkawa, Y., Sakata-Sogawa, K., Tokunaga, M., Nagase, T., Nozaki, N., McNally, J. G. & Kimura, H., 12 11 2014, : : Nature. 516, 7530, p. 272-275 4 p.

研究成果: ジャーナルへの寄稿記事

113 引用 (Scopus)

Relationship between the risk for a shrimp allergy and freshness or cooking

Usui, M., Harada, A., Yasumoto, S., Sugiura, Y., Nishidai, A., Ikarashi, M., Takaba, H., Miyasaki, T., Azakami, H. & Kondo, M., 1 1 2015, : : Bioscience, Biotechnology and Biochemistry. 79, 10, p. 1698-1701 4 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Reproductive organs regulate leaf nitrogen metabolism mediated by cytokinin signal

Igarashi, D., Izumi, Y., Dokiya, Y., Totsuka, K., Fukusaki, E. & Ohsumi, C., 2 1 2009, : : Planta. 229, 3, p. 633-644 12 p.

研究成果: ジャーナルへの寄稿記事

17 引用 (Scopus)

Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system

Fukuda, S., Nishida-Fukuda, H., Nanba, D., Nakashiro, K. I., Nakayama, H., Kubota, H. & Higashiyama, S., 2 2 2016, : : Scientific reports. 6, 20209.

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)