附属トランスオミクス医学研究センター

研究成果

記事

A novel missense mutation of RYR1 in familial idiopathic hyper CK-emia

Sano, K., Miura, S., Fujiwara, T., Fujioka, R., Yorita, A., Noda, K., Kida, H., Azuma, K., Kaieda, S., Yamamoto, K., Taniwaki, T., Fukumaki, Y. & Shibata, H., 9 15 2015, : : Journal of the Neurological Sciences. 356, 1-2, p. 142-147 6 p., 13864.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

A novel missense variant (Gln220Arg) of GNB4 encoding guanine nucleotide-binding protein, subunit beta-4 in a Japanese family with autosomal dominant motor and sensory neuropathy

Miura, S., Morikawa, T., Fujioka, R., Noda, K., Kosaka, K., Taniwaki, T. & Shibata, H., 9 2017, : : European Journal of Medical Genetics. 60, 9, p. 474-478 5 p.

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

Anti-tumour effects of antimicrobial peptides, components of the innate immune system, against haematopoietic tumours in Drosophila mxc mutants

Araki, M., Kurihara, M., Kinoshita, S., Awane, R., Sato, T., Ohkawa, Y. & Inoue, Y. H., 1 1 2019, : : DMM Disease Models and Mechanisms. 12, 6, dmm037721.

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公開
3 引用 (Scopus)

A one-step immunostaining method to visualize rodent muscle fiber type within a single specimen

Sawano, S., Komiya, Y., Ichitsubo, R., Ohkawa, Y., Nakamura, M., Tatsumi, R., Ikeuchi, Y. & Mizunoya, W., 11 2016, : : PloS one. 11, 11, 0166080.

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

A panel of specific monoclonal antibodies directed against various phosphorylated histones H3

Yoshimi, T., Ohkawa, Y., Azuma, M. & Tachibana, T., 4 1 2013, : : Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 32, 2, p. 119-124 6 p.

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

A rat monoclonal antibody against the chromatin remodeling factor CHD5

Yoshimura, S., Yoshimi, T., Ohkawa, Y., Azuma, M. & Tachibana, T., 2 1 2010, : : Hybridoma. 29, 1, p. 63-66 4 p.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

A shift in glutamine nitrogen metabolism contributes to the malignant progression of cancer

Kodama, M., Oshikawa, K., Shimizu, H., Yoshioka, S., Takahashi, M., Izumi, Y., Bamba, T., Tateishi, C., Tomonaga, T., Matsumoto, M. & Nakayama, K. I., 12 1 2020, : : Nature communications. 11, 1, 1320.

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公開

Association analysis of polymorphisms in the upstream region of the human dopamine D4 receptor gene (DRD4) with schizophrenia and personality traits

Mitsuyasu, H., Hirata, N., Sakai, Y., Shibata, H., Takeda, Y., Ninomiya, H., Kawasaki, H., Tashiro, N. & Fukumaki, Y., 3 10 2001, : : Journal of Human Genetics. 46, 1, p. 26-31 6 p.

研究成果: ジャーナルへの寄稿記事

71 引用 (Scopus)

Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia

Arai, S., Shibata, H., Sakai, M., Ninomiya, H., Lwata, N., Ozaki, N. & Fukumaki, Y., 2 1 2009, : : Psychiatric Genetics. 19, 1, p. 6-13 8 p.

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

Association study of polymorphisms in synaptic vesicle-associated genes, SYN2 and CPLX2, with schizophrenia

Lee, H. J., Song, J. Y., Kim, J. W., Jin, S. Y., Hong, M. S., Park, J. K., Chung, J. H., Shibata, H. & Fukumaki, Y., 8 31 2005, : : Behavioral and Brain Functions. 1, 15.

研究成果: ジャーナルへの寄稿記事

38 引用 (Scopus)

Association study of polymorphisms in the excitatory amino acid transporter 2 gene (SLC1A2) with schizophrenia

Deng, X., Shibata, H., Ninomiya, H., Tashiro, N., Iwata, N., Ozaki, N. & Fukumaki, Y., 8 6 2004, : : BMC Psychiatry. 4, 21.

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)

Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia

Shibata, H., Joo, A., Fujii, Y., Tani, A., Makino, C., Hirata, N., Kikuta, R., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 10 30 2001, : : Psychiatric Genetics. 11, 3, p. 139-144 6 p.

研究成果: ジャーナルへの寄稿記事

30 引用 (Scopus)

Association study of polymorphisms in the GluR6 kainate receptor gene (GRIK2) with schizophrenia

Shibata, H., Shibata, A., Ninomiya, H., Tashiro, N. & Fukumaki, Y., 12 15 2002, : : Psychiatry research. 113, 1-2, p. 59-67 9 p.

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19 引用 (Scopus)

Association study of polymorphisms in the GluR7, KA1 and KA2 kainate receptor genes (GRIK3, GRIK4, GRIK5) with schizophrenia

Shibata, H., Aramaki, T., Sakai, M., Ninomiya, H., Tashiro, N., Iwata, N., Ozaki, N. & Fukumaki, Y., 1 30 2006, : : Psychiatry research. 141, 1, p. 39-51 13 p.

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25 引用 (Scopus)

Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia

Deng, X., Shibata, H., Takeuchi, N., Rachi, S., Sakai, M., Ninomiya, H., Iwata, N., Ozaki, N. & Fukumaki, Y., 4 5 2007, : : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 144, 3, p. 271-278 8 p.

研究成果: ジャーナルへの寄稿記事

33 引用 (Scopus)

Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9 with schizophrenia

Deng, X., Sagata, N., Takeuchi, N., Tanaka, M., Ninomiya, H., Iwata, N., Ozaki, N., Shibata, H. & Fukumaki, Y., 7 18 2008, : : BMC Psychiatry. 8, 58.

研究成果: ジャーナルへの寄稿記事

18 引用 (Scopus)

A strategy for large-scale phosphoproteomics and SRM-based validation of human breast cancer tissue samples

Narumi, R., Murakami, T., Kuga, T., Adachi, J., Shiromizu, T., Muraoka, S., Kume, H., Kodera, Y., Matsumoto, M., Nakayama, K., Miyamoto, Y., Ishitobi, M., Inaji, H., Kato, K. & Tomonaga, T., 11 2 2012, : : Journal of Proteome Research. 11, 11, p. 5311-5322 12 p.

研究成果: ジャーナルへの寄稿記事

67 引用 (Scopus)

A triad of serum response factor and the GATA and NK families governs the transcription of smooth and cardiac muscle genes

Nishida, W., Nakamura, M., Mori, S., Takahashi, M., Ohkawa, Y., Tadokoro, S., Yoshida, K., Hiwada, K., Hayashi, K. N. I. & Sobue, K., 3 1 2002, : : Journal of Biological Chemistry. 277, 9, p. 7308-7317 10 p.

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84 引用 (Scopus)

Bcl11b sets pro-T cell fate by site-specific cofactor recruitment and by repressing Id2 and Zbtb16

Hosokawa, H., Romero-Wolf, M., Yui, M. A., Ungerbäck, J., Quiloan, M. L. G., Matsumoto, M., Nakayama, K. I., Tanaka, T. & Rothenberg, E. V., 12 1 2018, : : Nature Immunology. 19, 12, p. 1427-1440 14 p.

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11 引用 (Scopus)

Biochemical analysis of nucleosome targeting by Tn5 transposase

Sato, S., Arimura, Y., Kujirai, T., Harada, A., Maehara, K., Nogami, J., Ohkawa, Y. & Kurumizaka, H., 8 1 2019, : : Open Biology. 9, 8, 190116.

研究成果: ジャーナルへの寄稿記事

公開

Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1

Sasaki, F., Koga, T., Saeki, K., Okuno, T., Kazuno, S., Fujimura, T., Ohkawa, Y. & Yokomizo, T., 9 2017, : : PloS one. 12, 9, e0185133.

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4 引用 (Scopus)

Biochemical characterization of CYP505D6, a self-sufficient cytochrome P450 from the white-rot fungus Phanerochaete chrysosporium

Sakai, K., Matsuzaki, F., Wise, L., Sakai, Y., Jindou, S., Ichinose, H., Takaya, N., Kato, M., Wariishi, H. & Shimizu, M., 11 1 2018, : : Applied and environmental microbiology. 84, 22, e01091-18.

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3 引用 (Scopus)

Blue light-induced autophosphorylation of phototropin is a primary step for signaling

Inoue, S. I., Kinoshita, T., Matsumoto, M., Nakayama, K. I., Doi, M. & Shimazaki, K. I., 4 8 2008, : : Proceedings of the National Academy of Sciences of the United States of America. 105, 14, p. 5626-5631 6 p.

研究成果: ジャーナルへの寄稿記事

157 引用 (Scopus)

Calcineurin broadly regulates the initiation of skeletal muscle-specific gene expression by binding target promoters and facilitating the interaction of the SWI/SNF chromatin remodeling enzyme

Witwicka, H., Nogami, J., Syed, S. A., Maehara, K., Padilla-Benavides, T., Ohkawa, Y. & Imbalzano, A. N., 10 1 2019, : : Molecular and cellular biology. 39, 19, e00063-19.

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2 引用 (Scopus)

Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome

Arimura, Y., Ikura, M., Fujita, R., Noda, M., Kobayashi, W., Horikoshi, N., Sun, J., Shi, L., Kusakabe, M., Harata, M., Ohkawa, Y., Tashiro, S., Kimura, H., Ikura, T. & Kurumizaka, H., 1 1 2018, : : Nucleic acids research. 46, 19, p. 10007-10018 12 p.

研究成果: ジャーナルへの寄稿記事

7 引用 (Scopus)

Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture

Sugimoto, N., Maehara, K., Yoshida, K., Yasukouchi, S., Osano, S., Watanabe, S., Aizawa, M., Yugawa, T., Kiyono, T., Kurumizaka, H., Ohkawa, Y. & Fujita, M., 1 1 2015, : : Nucleic acids research. 43, 12, p. 5898-5911 14 p.

研究成果: ジャーナルへの寄稿記事

23 引用 (Scopus)

Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires HeS1 to bind diverse DNA sites

Noguchi, Y. T., Nakamura, M., Hino, N., Nogami, J., Tsuji, S., Sato, T., Zhang, L., Tsujikawa, K., Tanaka, T., Izawa, K., Okada, Y., Doi, T., Kokubo, H., Harada, A., Uezumi, A., Gessler, M., Ohkawa, Y. & Fukada, S. I., 2 2019, : : Development (Cambridge). 146, 4, dev163618.

研究成果: ジャーナルへの寄稿記事

公開
3 引用 (Scopus)

Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo

Akieda, Y., Ogamino, S., Furuie, H., Ishitani, S., Akiyoshi, R., Nogami, J., Masuda, T., Shimizu, N., Ohkawa, Y. & Ishitani, T., 12 1 2019, : : Nature communications. 10, 1, 4710.

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1 引用 (Scopus)

Cell cycle-dependent expression of mammalian E2-C regulated by the anaphase-promoting complex/cyclosome

Yamanaka, A., Hatakeyama, S., Kominami, K. I., Kitagawa, M., Matsumoto, M. & Nakayama, K. I., 1 1 2000, : : Molecular biology of the cell. 11, 8, p. 2821-2831 11 p.

研究成果: ジャーナルへの寄稿記事

44 引用 (Scopus)

Cell cycle–dependent localization of the proteasome to chromatin

Kito, Y., Matsumoto, M., Hatano, A., Takami, T., Oshikawa, K., Matsumoto, A. & Nakayama, K. I., 12 1 2020, : : Scientific reports. 10, 1, 5801.

研究成果: ジャーナルへの寄稿記事

公開

Characterization of the mouse gene for the U-box-type ubiquitin ligase UFD2a

Kaneko, C., Hatakeyama, S., Matsumoto, M., Yada, M., Nakayama, K. & Nakayama, K., 1 10 2003, : : Biochemical and Biophysical Research Communications. 300, 2, p. 297-304 8 p.

研究成果: ジャーナルへの寄稿記事

47 引用 (Scopus)

Chd2 interacts with H3.3 to determine myogenic cell fate

Harada, A., Okada, S., Konno, D., Odawara, J., Yoshimi, T., Yoshimura, S., Kumamaru, H., Saiwai, H., Tsubota, T., Kurumizaka, H., Akashi, K., Tachibana, T., Imbalzano, A. N. & Ohkawa, Y., 7 4 2012, : : EMBO Journal. 31, 13, p. 2994-3007 14 p.

研究成果: ジャーナルへの寄稿記事

69 引用 (Scopus)

Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells

Semba, Y., Harada, A., Maehara, K., Oki, S., Meno, C., Ueda, J., Yamagata, K., Suzuki, A., Onimaru, M., Nogami, J., Okada, S., Akashi, K. & Ohkawa, Y., 9 1 2017, : : Nucleic acids research. 45, 15, p. 8758-8772 15 p.

研究成果: ジャーナルへの寄稿記事

11 引用 (Scopus)

Chd5 Regulates MuERV-L/MERVL Expression in Mouse Embryonic Stem Cells Via H3K27me3 Modification and Histone H3.1/H3.2

Hayashi, M., Maehara, K., Harada, A., Semba, Y., Kudo, K., Takahashi, H., Oki, S., Meno, C., Ichiyanagi, K., Akashi, K. & Ohkawa, Y., 3 2016, : : Journal of Cellular Biochemistry. 117, 3, p. 780-792 13 p.

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16 引用 (Scopus)

CHD8 haploinsufficiency results in autistic-like phenotypes in mice

Katayama, Y., Nishiyama, M., Shoji, H., Ohkawa, Y., Kawamura, A., Sato, T., Suyama, M., Takumi, T., Miyakawa, T. & Nakayama, K. I., 1 1 2016, : : Nature. 537, 7622, p. 675-679 5 p.

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86 引用 (Scopus)

Chromatin accessibility and transcription factor binding at the PPARγ2 promoter during adipogenesis is protein kinase A-dependent

Xiao, H., LeBlanc, S. E., Wu, Q., Konda, S., Salma, N., Marfella, C. G. A., Ohkawa, Y. & Imbalzano, A. N., 1 1 2011, : : Journal of cellular physiology. 226, 1, p. 86-93 8 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing

Kobayashi, W., Takaku, M., Machida, S., Tachiwana, H., Maehara, K., Ohkawa, Y. & Kurumizaka, H., 4 7 2016, : : Scientific reports. 6, 24228.

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto HOX clusters causing aberrant HOX expression in leukemia cells

Oka, M., Mura, S., Otani, M., Miyamoto, Y., Nogami, J., Maehara, K., Harada, A., Tachibana, T., Yoneda, Y. & Ohkawa, Y., 11 2019, : : eLife. 8, e46667.

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Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes

Oka, M., Mura, S., Yamada, K., Sangel, P., Hirata, S., Maehara, K., Kawakami, K., Tachibana, T., Ohkawa, Y., Kimura, H. & Yoneda, Y., 1 7 2016, : : eLife. 5, JANUARY2016, e09540.

研究成果: ジャーナルへの寄稿記事

15 引用 (Scopus)

CLEC3A, MMP7, and LCN2 as novel markers for predicting recurrence in resected G1 and G2 pancreatic neuroendocrine tumors

Miki, M., Oono, T., Fujimori, N., Takaoka, T., Kawabe, K., Miyasaka, Y., Ohtsuka, T., Saito, D., Nakamura, M., Ohkawa, Y., Oda, Y., Suyama, M., Ito, T. & Ogawa, Y., 7 2019, : : Cancer Medicine. 8, 8, p. 3748-3760 13 p.

研究成果: ジャーナルへの寄稿記事

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2 引用 (Scopus)

Comparative analysis of human Src-family kinase substrate specificity in vitro

Takeda, H., Kawamura, Y., Miura, A., Mori, M., Wakamatsu, A., Yamamoto, J. I., Isogai, T., Matsumoto, M., Nakayama, K., Natsume, T., Nomura, N. & Goshima, N., 11 5 2010, : : Journal of Proteome Research. 9, 11, p. 5982-5993 12 p.

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15 引用 (Scopus)
公開
2 引用 (Scopus)

Comparison of sequential derivatization with concurrent methods for GC/MS-based metabolomics

Miyagawa, H. & Bamba, T., 2 2019, : : Journal of Bioscience and Bioengineering. 127, 2, p. 160-168 9 p.

研究成果: ジャーナルへの寄稿記事

2 引用 (Scopus)

Comparison of the microbial community structure between inflamed and non-inflamed sites in patients with ulcerative colitis

Hirano, A., Umeno, J., Okamoto, Y., Shibata, H., Ogura, Y., Moriyama, T., Torisu, T., Fujioka, S., Fuyuno, Y., Kawarabayasi, Y., Matsumoto, T., Kitazono, T. & Esaki, M., 9 2018, : : Journal of Gastroenterology and Hepatology (Australia). 33, 9, p. 1590-1597 8 p.

研究成果: ジャーナルへの寄稿記事

22 引用 (Scopus)

Comprehensive identification of substrates for f-box proteins by differential proteomics analysis

Yumimoto, K., Matsumoto, M., Oyamada, K., Moroishi, T. & Nakayama, K. I., 6 1 2012, : : Journal of Proteome Research. 11, 6, p. 3175-3185 11 p.

研究成果: ジャーナルへの寄稿記事

25 引用 (Scopus)

Construction and analysis of EST libraries of the trans-polyisoprene producing plant, Eucommia ulmoides Oliver

Suzuki, N., Uefuji, H., Nishikawa, T., Mukai, Y., Yamashita, A., Hattori, M., Ogasawara, N., Bamba, T., Fukusaki, E. I., Kobayashi, A., Ogata, Y., Sakurai, N., Suzuki, H., Shibata, D. & Nakazawa, Y., 10 1 2012, : : Planta. 236, 5, p. 1405-1417 13 p.

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21 引用 (Scopus)

Control of tissue size and development by a regulatory element in the yorkie 3'UTR

Umegawachi, T., Yoshida, H., Koshida, H., Yamada, M., Ohkawa, Y., Sato, T., Suyama, M., Krause, H. M. & Yamaguchi, M., 1 1 2017, : : American Journal of Cancer Research. 7, 3, p. 673-687 15 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)

Crohn's disease risk alleles on the NOD2 locus have been maintained by natural selection on standing variation

Nakagome, S., Mano, S., Kozlowski, L., Bujnicki, J. M., Shibata, H., Fukumaki, Y., Kidd, J. R., Kidd, K. K., Kawamura, S. & Oota, H., 6 1 2012, : : Molecular Biology and Evolution. 29, 6, p. 1569-1585 17 p.

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12 引用 (Scopus)

Cryo-EM structure of the nucleosome containing the ALB1 enhancer DNA sequence

Takizawa, Y., Tanaka, H., Machida, S., Koyama, M., Maehara, K., Ohkawa, Y., Wade, P. A., Wolf, M. & Kurumizaka, H., 1 1 2018, : : Open Biology. 8, 3, 170255.

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8 引用 (Scopus)

Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8

Taguchi, H., Xie, Y., Horikoshi, N., Maehara, K., Harada, A., Nogami, J., Sato, K., Arimura, Y., Osakabe, A., Kujirai, T., Iwasaki, T., Semba, Y., Tachibana, T., Kimura, H., Ohkawa, Y. & Kurumizaka, H., 4 25 2017, : : Biochemistry. 56, 16, p. 2184-2196 13 p.

研究成果: ジャーナルへの寄稿記事

5 引用 (Scopus)