トランスオミクス医学研究センター

研究成果 1994 2020

2018
1 引用 (Scopus)

Erratum: Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding (Immunity (2018) 48(6) (1119–1134.e7), (S1074761318301936) (10.1016/j.immuni.2018.04.024))

Hosokawa, H., Ungerbäck, J., Wang, X., Matsumoto, M., Nakayama, K. I., Cohen, S. M., Tanaka, T. & Rothenberg, E. V., 10 16 2018, : : Immunity. 49, 4, 1 p.

研究成果: ジャーナルへの寄稿コメント/討論

Immunity
Transcription Factors
T-Lymphocytes
Gene Expression
proto-oncogene protein Spi-1
5 引用 (Scopus)

Fetal leydig cells dedifferentiate and serve as adult leydig stem cells

Shima, Y., Miyabayashi, K., Sato, T., Suyama, M., Ohkawa, Y., Doi, M., Okamura, H. & Suzuki, K., 12 2018, : : Development (Cambridge). 145, 23, dev169136.

研究成果: ジャーナルへの寄稿記事

Adult Stem Cells
Leydig Cells
Pericytes
Essential Genes
Cell Lineage

Genome-wide analysis of the spatiotemporal regulation of firing and dormant replication origins in human cells

Sugimoto, N., Maehara, K., Yoshida, K., Ohkawa, Y. & Fujita, M., 7 27 2018, : : Nucleic Acids Research. 46, 13, p. 6683-6696 14 p.

研究成果: ジャーナルへの寄稿記事

Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome
13 引用 (Scopus)
Spatio-Temporal Analysis
Replication Origin
Chromatin
Transcription Initiation Site
Genome
3 引用 (Scopus)

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system

Watanabe, S., Fujiyama, H., Takafuji, T., Kayama, K., Matsumoto, M., Nakayama, K. I., Yoshida, K., Sugimoto, N. & Fujita, M., 8 1 2018, : : Journal of Cell Science. 131, 15

研究成果: ジャーナルへの寄稿記事

Ribosomal Proteins
Proteasome Endopeptidase Complex
Ubiquitin
Glutamic Acid
Down-Regulation

Highly Accurate Detection and Identification Methodology of Xenobiotic Metabolites Using Stable Isotope Labeling, Data Mining Techniques, and Time-Dependent Profiling Based on LC/HRMS/MS

Takahashi, M., Izumi, Y., Iwahashi, F., Nakayama, Y., Iwakoshi, M., Nakao, M., Yamato, S., Fukusaki, E. & Bamba, T., 8 7 2018, : : Analytical chemistry. 90, 15, p. 9068-9076 9 p.

研究成果: ジャーナルへの寄稿記事

Xenobiotics
Metabolites
2,4-Dichlorophenoxyacetic Acid
Isotopes
Labeling

Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration

Harada, A., Maehara, K., Ono, Y., Taguchi, H., Yoshioka, K., Kitajima, Y., Xie, Y., Sato, Y., Iwasaki, T., Nogami, J., Okada, S., Komatsu, T., Semba, Y., Takemoto, T., Kimura, H., Kurumizaka, H. & Ohkawa, Y., 12 1 2018, : : Nature communications. 9, 1, 1400.

研究成果: ジャーナルへの寄稿記事

skeletal muscle
chromatin
Nucleosomes
regeneration
Histones
4 引用 (Scopus)

Hypoxanthine Secretion from Human Adipose Tissue and its Increase in Hypoxia

Nagao, H., Nishizawa, H., Tanaka, Y., Fukata, T., Mizushima, T., Furuno, M., Bamba, T., Tsushima, Y., Fujishima, Y., Kita, S., Funahashi, T., Maeda, N., Mori, M., Fukusaki, E. & Shimomura, I., 7 1 2018, : : Obesity. 26, 7, p. 1168-1178 11 p.

研究成果: ジャーナルへの寄稿記事

Hypoxanthine
Adipose Tissue
White Adipose Tissue
Uric Acid
Adipocytes
6 引用 (Scopus)

Identification of miR-305, a microRNA that promotes aging, and its target mRNAs in Drosophila

Ueda, M., Sato, T., Ohkawa, Y. & Inoue, Y. H., 2 1 2018, : : Genes to Cells. 23, 2, p. 80-93 14 p.

研究成果: ジャーナルへの寄稿記事

MicroRNAs
Drosophila
Messenger RNA
Diptera
Peptides
2 引用 (Scopus)

Identification of the physiological substrates of PDIp, a pancreas-specific protein-disulfide isomerase family member

Fujimoto, T., Nakamura, O., Saito, M., Tsuru, A., Matsumoto, M., Kohno, K., Inaba, K. & Kadokura, H., 1 1 2018, : : Journal of Biological Chemistry. 293, 48, p. 18421-18433 13 p.

研究成果: ジャーナルへの寄稿記事

Protein Disulfide-Isomerases
Pancreas
Enzyme Precursors
Pancreatic Elastase
Substrates

Identifying metabolic elements that contribute to productivity of 1-propanol bioproduction using metabolomic analysis

Putri, S. P., Nakayama, Y., Shen, C., Noguchi, S., Nitta, K., Bamba, T., Pontrelli, S., Liao, J. & Fukusaki, E., 7 1 2018, : : Metabolomics. 14, 7, 96.

研究成果: ジャーナルへの寄稿記事

1-Propanol
Metabolomics
Threonine
Productivity
Escherichia coli
4 引用 (Scopus)

Increase in hepatic and decrease in peripheral insulin clearance characterize abnormal temporal patterns of serum insulin in diabetic subjects

Ohashi, K., Fujii, M., Uda, S., Kubota, H., Komada, H., Sakaguchi, K., Ogawa, W. & Kuroda, S., 12 1 2018, : : npj Systems Biology and Applications. 4, 1, 14.

研究成果: ジャーナルへの寄稿記事

Insulin
Clearance
Decrease
Diabetes Mellitus
Liver

Increase in hepatic and decrease in peripheral insulin clearance characterize abnormal temporal patterns of serum insulin in diabetic subjects

Ohashi, K., Fujii, M., Uda, S., Kubota, H., Komada, H., Sakaguchi, K., Ogawa, W. & Kuroda, S., 2018, : : npj Systems Biology and Applications. 4, 14.

研究成果: ジャーナルへの寄稿記事

公開
Insulin
Liver
Serum
Type 2 Diabetes Mellitus
Glucose
2 引用 (Scopus)

Insulin-like growth factor 1 receptor stabilizes the ETV6-NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation

Tognon, C. E., Rafn, B., Cetinbas, N. M., Kamura, T., Trigo, G., Rotblat, B., Okumura, F., Matsumoto, M., Chow, C., Davare, M., Pollak, M., Mayor, T. & Sorensen, P. H., 1 1 2018, : : Journal of Biological Chemistry. 293, 32, p. 12502-12515 14 p.

研究成果: ジャーナルへの寄稿記事

Somatomedin Receptors
Oncogene Proteins
Receptor Protein-Tyrosine Kinases
Somatomedins
Degradation
3 引用 (Scopus)

In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver

Kubota, H., Uda, S., Matsuzaki, F., Yamauchi, Y. & Kuroda, S., 7 25 2018, : : Cell Systems. 7, 1, p. 118-128.e3

研究成果: ジャーナルへの寄稿記事

Insulin
Liver
Hormones
Homeostasis
Glucose Clamp Technique

Matrix rank minimization approach to signal recovery and nonlinear function estimation for nonlinear ARX model with input nonlinearity

Konishi, K., Fujii, M., Kunida, K., Uda, S. & Kuroda, S., 2 7 2018, 2017 Asian Control Conference, ASCC 2017. Institute of Electrical and Electronics Engineers Inc., p. 1428-1431 4 p. (2017 Asian Control Conference, ASCC 2017; 巻数 2018-January).

研究成果: 著書/レポートタイプへの貢献会議での発言

Nonlinear Estimation
Function Estimation
Autoregressive Model
Nonlinear Function
Nonlinear Model

Matrix rank minimization approach to signal recovery and nonlinear function estimation for nonlinear ARX model with input nonlinearity

Konishi, K., Fujii, M., Kunida, K., Uda, S. & Kuroda, S., 2 8 2018, Control Conference (ASCC), 2017 11th Asian. IEEE

研究成果: 著書/レポートタイプへの貢献会議での発言

Recovery
Signal transduction
Systems Biology
1 引用 (Scopus)

Metabolomics approach to reduce the Crabtree effect in continuous culture of Saccharomyces cerevisiae

Imura, M., Iwakiri, R., Bamba, T. & Fukusaki, E., 8 2018, : : Journal of Bioscience and Bioengineering. 126, 2, p. 183-188 6 p.

研究成果: ジャーナルへの寄稿記事

Metabolomics
Yeast
Saccharomyces cerevisiae
Ethanol
Dilution
7 引用 (Scopus)

Microbe participation in aroma production during soy sauce fermentation

Harada, R., Yuzuki, M., Ito, K., Shiga, K., Bamba, T. & Fukusaki, E., 6 2018, : : Journal of Bioscience and Bioengineering. 125, 6, p. 688-694 7 p.

研究成果: ジャーナルへの寄稿記事

Soy Foods
Lactic acid
Fermentation
Lactic Acid
Acetic acid
1 引用 (Scopus)

MNase, as a probe to study the sequence-dependent site exposures in the +1 nucleosomes of yeast

Luo, D., Kato, D., Nogami, J., Ohkawa, Y., Kurumizaka, H. & Kono, H., 1 1 2018, : : Nucleic acids research. 46, 14, p. 7124-7137 14 p.

研究成果: ジャーナルへの寄稿記事

Nucleosomes
Yeasts
DNA
Digestion
Saccharomycetales
24 引用 (Scopus)

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth

Morita, M., Sato, T., Nomura, M., Sakamoto, Y., Inoue, Y., Tanaka, R., Ito, S., Kurosawa, K., Yamaguchi, K., Sugiura, Y., Takizaki, H., Yamashita, Y., Katakura, R., Sato, I., Kawai, M., Okada, Y., Watanabe, H., Kondoh, G., Matsumoto, S., Kishimoto, A. および12人, Obata, M., Matsumoto, M., Fukuhara, T., Motohashi, H., Suematsu, M., Komatsu, M., Nakayama, K. I., Watanabe, T., Soga, T., Shima, H., Maemondo, M. & Tanuma, N., 3 12 2018, : : Cancer Cell. 33, 3, p. 355-367.e7

研究成果: ジャーナルへの寄稿記事

Small Cell Lung Carcinoma
Growth
Neoplasms
Protein Isoforms
Neuroendocrine Tumors
5 引用 (Scopus)

Prolonged inhibition of hepatocellular carcinoma cell proliferation by combinatorial expression of defined transcription factors

Takashima, Y., Horisawa, K., Udono, M., Ohkawa, Y. & Suzuki, A., 11 1 2018, : : Cancer Science. 109, 11, p. 3543-3553 11 p.

研究成果: ジャーナルへの寄稿記事

Hepatocellular Carcinoma
Transcription Factor 3
Transcription Factors
Cell Proliferation
Cell Line

Response to the letter to the editor by Berciano J & García A

Miura, S. & Shibata, H., 1 2018, : : European Journal of Medical Genetics. 61, 1, 1 p.

研究成果: ジャーナルへの寄稿レター

1 引用 (Scopus)

Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders

Shiraishi, K., Shindo, A., Harada, A., Kurumizaka, H., Kimura, H., Ohkawa, Y. & Matsuyama, H., 1 2018, : : Andrology. 6, 1, p. 158-165 8 p.

研究成果: ジャーナルへの寄稿記事

Azoospermia
Spermatogenesis
Histones
Testis
Proliferating Cell Nuclear Antigen
5 引用 (Scopus)

Sensitive detection of fluorescence in western blotting by merging images

Kondo, Y., Higa, S., Iwasaki, T., Matsumoto, T., Maehara, K., Harada, A., Baba, Y., Fujita, M. & Ohkawa, Y., 1 2018, : : PloS one. 13, 1, e0191532.

研究成果: ジャーナルへの寄稿記事

Merging
Western blotting
Fluorescence
Western Blotting
fluorescence
8 引用 (Scopus)

Silica-based hybrid porous layers to enhance the retention and efficiency of open tubular capillary columns with a 5 μm inner diame9ter

Hara, T., Izumi, Y., Nakao, M., Hata, K., Baron, G. V., Bamba, T. & Desmet, G., 12 14 2018, : : Journal of Chromatography A. 1580, p. 63-71 9 p.

研究成果: ジャーナルへの寄稿記事

Silicon Dioxide
Hydrophobicity
Hydrophobic and Hydrophilic Interactions
Mass transfer
tetramethoxysilane

Sparse Gaussian graphical model with missing values

Uda, S. & Kubota, H., 1 8 2018, Proceedings of the 21st Conference of Open Innovations Association, FRUCT 2017. IEEE Computer Society, p. 336-343 8 p.

研究成果: 著書/レポートタイプへの貢献会議での発言

Signal transduction
Molecular interactions
Factorization
Genes
Proteins

TDRKH is a candidate gene for an autosomal dominant distal hereditary motor neuropathy

Miura, S., Kosaka, K., Nomura, T., Nagata, S., Shimojo, T., Morikawa, T., Fujioka, R., Harada, M., Taniwaki, T. & Shibata, H., 1 1 2018, (受理済み/印刷中) : : European Journal of Medical Genetics.

研究成果: ジャーナルへの寄稿記事

Dominant Genes
Exome
Genes
Muscle Weakness
Motor Neurons

The Autism-Related Protein CHD8 Cooperates with C/EBPβ to Regulate Adipogenesis

Kita, Y., Katayama, Y., Shiraishi, T., Oka, T., Sato, T., Suyama, M., Ohkawa, Y., Miyata, K., Oike, Y., Shirane, M., Nishiyama, M. & Nakayama, K. I., 5 15 2018, : : Cell Reports. 23, 7, p. 1988-2000 13 p.

研究成果: ジャーナルへの寄稿記事

CCAAT-Enhancer-Binding Proteins
Adipogenesis
Autistic Disorder
White Adipose Tissue
Peroxisome Proliferator-Activated Receptors
11 引用 (Scopus)

The habu genome reveals accelerated evolution of venom protein genes

Shibata, H., Chijiwa, T., Oda-Ueda, N., Nakamura, H., Yamaguchi, K., Hattori, S., Matsubara, K., Matsuda, Y., Yamashita, A., Isomoto, A., Mori, K., Tashiro, K., Kuhara, S., Yamasaki, S., Fujie, M., Goto, H., Koyanagi, R., Takeuchi, T., Fukumaki, Y., Ohno, M. および4人, Shoguchi, E., Hisata, K., Satoh, N. & Ogawa, T., 12 1 2018, : : Scientific reports. 8, 1, 11300.

研究成果: ジャーナルへの寄稿記事

venoms
snakes
genome
genes
proteins
28 引用 (Scopus)

The prehistoric peopling of Southeast Asia

McColl, H., Racimo, F., Vinner, L., Demeter, F., Gakuhari, T., Víctor Moreno-Mayar, J., Van Driem, G., Wilken, U. G., Seguin-Orlando, A., De la Fuente Castro, C., Wasef, S., Shoocongdej, R., Souksavatdy, V., Sayavongkhamdy, T., Saidin, M. M., Allentoft, M. E., Sato, T., Malaspinas, A. S., Aghakhanian, F. A., Korneliussen, T. および46人, Prohaska, A., Margaryan, A., De Barros Damgaard, P., Kaewsutthi, S., Lertrit, P., Nguyen, T. M. H., Hung, H. C., Tran, T. M., Truong, H. N., Nguyen, G. H., Shahidan, S., Wiradnyana, K., Matsumae, H., Shigehara, N., Yoneda, M., Ishida, H., Masuyama, T., Yamada, Y., Tajima, A., Shibata, H., Toyoda, A., Hanihara, T., Nakagome, S., Deviese, T., Bacon, A. M., Duringer, P., Ponche, J. L., Shackelford, L., Patole-Edoumba, E., Nguyen, A. T., Bellina-Pryce, B., Galipaud, J. C., Kinaston, R., Buckley, H., Pottier, C., Rasmussen, S., Higham, T., Foley, R. A., Lahr, M. M., Orlando, L., Sikora, M., Phipps, M. E., Oota, H., Higham, C., Lambert, D. M. & Willerslev, E., 7 6 2018, : : Science. 361, 6397, p. 88-92 5 p.

研究成果: ジャーナルへの寄稿記事

Southeastern Asia
Agriculture
Vietnam
Human Genome
Islands
6 引用 (Scopus)

The promise of targeted proteomics for quantitative network biology

Matsumoto, M. & Nakayama, K., 12 1 2018, : : Current Opinion in Biotechnology. 54, p. 88-97 10 p.

研究成果: ジャーナルへの寄稿評論記事

Proteomics
Proteins
Assays
Biological Phenomena
Recombinant proteins
17 引用 (Scopus)

Transcription Factor PU.1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding

Hosokawa, H., Ungerbäck, J., Wang, X., Matsumoto, M., Nakayama, K. I., Cohen, S. M., Tanaka, T. & Rothenberg, E. V., 6 19 2018, : : Immunity. 48, 6, p. 1119-1134.e7

研究成果: ジャーナルへの寄稿記事

Transcription Factors
T-Lymphocytes
Gene Expression
Genes
Binding Sites

Trans-omic Analysis Reveals Selective Responses to Induced and Basal Insulin across Signaling, Transcriptional, and Metabolic Networks

Kawata, K., Hatano, A., Yugi, K., Sano, T., Fujii, M., Tomizawa, Y., Kokaji, T., Tanaka, K. Y., Uda, S., Suzuki, Y., Matsumoto, M., Nakayama, K., Saitoh, K., Kato, K., Ueno, A., Ohishi, M., Hirayama, A., Soga, T. & Kuroda, S., 2018, : : iScience. 7, p. 212-229

研究成果: ジャーナルへの寄稿記事

Gene Regulatory Networks
Metabolic Networks and Pathways
Insulin
Immediate-Early Genes
Metabolomics
7 引用 (Scopus)

Trans-omic Analysis Reveals Selective Responses to Induced and Basal Insulin across Signaling, Transcriptional, and Metabolic Networks

Kawata, K., Hatano, A., Yugi, K., Kubota, H., Sano, T., Fujii, M., Tomizawa, Y., Kokaji, T., Tanaka, K. Y., Uda, S., Suzuki, Y., Matsumoto, M., Nakayama, K. I., Saitoh, K., Kato, K., Ueno, A., Ohishi, M., Hirayama, A., Soga, T. & Kuroda, S., 9 28 2018, : : iScience. 7, p. 212-229 18 p.

研究成果: ジャーナルへの寄稿記事

公開
Gene Regulatory Networks
Metabolic Networks and Pathways
insulin
Insulin
Immediate-Early Genes
13 引用 (Scopus)

Widely-targeted quantitative lipidomics method by supercritical fluid chromatography triple quadrupole mass spectrometry

Takeda, H., Izumi, Y., Takahashi, M., Paxton, T., Tamura, S., Koike, T., Yu, Y., Kato, N., Nagase, K., Shiomi, M. & Bamba, T., 1 1 2018, : : Journal of Lipid Research. 59, 7, p. 1283-1293 11 p.

研究成果: ジャーナルへの寄稿記事

Supercritical Fluid Chromatography
Mass spectrometry
Mass Spectrometry
Lipids
Biomarkers
2019
13 引用 (Scopus)

A chromatin integration labelling method enables epigenomic profiling with lower input

Harada, A., Maehara, K., Handa, T., Arimura, Y., Nogami, J., Hayashi-Takanaka, Y., Shirahige, K., Kurumizaka, H., Kimura, H. & Ohkawa, Y., 2 1 2019, : : Nature Cell Biology. 21, 2, p. 287-296 10 p.

研究成果: ジャーナルへの寄稿記事

Epigenomics
Chromatin
Chromatin Immunoprecipitation
Histone Code
Immunoprecipitation

A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen

Oshikawa, K., Matsumoto, M., Kodama, M., Shimizu, H. & Nakayama, K. I., 1 1 2019, (受理済み/印刷中) : : Oncogene.

研究成果: ジャーナルへの寄稿記事

Simian virus 40
Viral Tumor Antigens
Carcinogenesis
Oncogenes
Heterochromatin

A highly sensitive determination method for acrylamide in beverages, grains, and confectioneries by supercritical fluid chromatography tandem mass spectrometry

Yoshioka, T., Izumi, Y., Nagatomi, Y., Miyamoto, Y., Suzuki, K. & Bamba, T., 10 1 2019, : : Food Chemistry. 294, p. 486-492 7 p.

研究成果: ジャーナルへの寄稿記事

supercritical fluid chromatography
Supercritical Fluid Chromatography
Beverages
Acrylamide
acrylamides

Alternative mRNA splicing in three venom families underlying a possible production of divergent venom proteins of the habu snake, protobothrops flavoviridis

Ogawa, T., Oda-Ueda, N., Hisata, K., Nakamura, H., Chijiwa, T., Hattori, S., Isomoto, A., Yugeta, H., Yamasaki, S., Fukumaki, Y., Ohno, M., Satoh, N. & Shibata, H., 10 9 2019, : : Toxins. 11, 10, 581.

研究成果: ジャーナルへの寄稿記事

公開
Trimeresurus
Snakes
Venoms
Alternative Splicing
Genes
2 引用 (Scopus)

Anti-tumour effects of antimicrobial peptides, components of the innate immune system, against haematopoietic tumours in Drosophila mxc mutants

Araki, M., Kurihara, M., Kinoshita, S., Awane, R., Sato, T., Ohkawa, Y. & Inoue, Y. H., 1 1 2019, : : DMM Disease Models and Mechanisms. 12, 6, dmm037721.

研究成果: ジャーナルへの寄稿記事

公開
Immune system
Drosophila
Tumors
Immune System
Peptides

Biochemical analysis of nucleosome targeting by Tn5 transposase

Sato, S., Arimura, Y., Kujirai, T., Harada, A., Maehara, K., Nogami, J., Ohkawa, Y. & Kurumizaka, H., 8 1 2019, : : Open Biology. 9, 8, 190116.

研究成果: ジャーナルへの寄稿記事

公開
Nucleosomes
DNA
Tn5 transposase
DNA sequences
Genomics

Calcineurin broadly regulates the initiation of skeletal muscle-specific gene expression by binding target promoters and facilitating the interaction of the SWI/SNF chromatin remodeling enzyme

Witwicka, H., Nogami, J., Syed, S. A., Maehara, K., Padilla-Benavides, T., Ohkawa, Y. & Imbalzano, A. N., 10 1 2019, : : Molecular and cellular biology. 39, 19, e00063-19.

研究成果: ジャーナルへの寄稿記事

公開
Chromatin Assembly and Disassembly
Calcineurin
Skeletal Muscle
Gene Expression
Enzymes
3 引用 (Scopus)

Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires HeS1 to bind diverse DNA sites

Noguchi, Y. T., Nakamura, M., Hino, N., Nogami, J., Tsuji, S., Sato, T., Zhang, L., Tsujikawa, K., Tanaka, T., Izawa, K., Okada, Y., Doi, T., Kokubo, H., Harada, A., Uezumi, A., Gessler, M., Ohkawa, Y. & Fukada, S. I., 2 2019, : : Development (Cambridge). 146, 4, dev163618.

研究成果: ジャーナルへの寄稿記事

公開
Muscle Cells
Stem Cells
DNA
Myogenin
Chromatin

Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo

Akieda, Y., Ogamino, S., Furuie, H., Ishitani, S., Akiyoshi, R., Nogami, J., Masuda, T., Shimizu, N., Ohkawa, Y. & Ishitani, T., 12 1 2019, : : Nature communications. 10, 1, 4710.

研究成果: ジャーナルへの寄稿記事

公開
embryos
Zebrafish
Embryonic Structures
Catenins
gradients

Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto HOX clusters causing aberrant HOX expression in leukemia cells

Oka, M., Mura, S., Otani, M., Miyamoto, Y., Nogami, J., Maehara, K., Harada, A., Tachibana, T., Yoneda, Y. & Ohkawa, Y., 11 22 2019, : : eLife. 8

研究成果: ジャーナルへの寄稿記事

公開
Nuclear Pore Complex Proteins
Chromatin
Leukemia
Nuclear Export Signals
Proteins
2 引用 (Scopus)

CLEC3A, MMP7, and LCN2 as novel markers for predicting recurrence in resected G1 and G2 pancreatic neuroendocrine tumors

Miki, M., Oono, T., Fujimori, N., Takaoka, T., Kawabe, K., Miyasaka, Y., Ohtsuka, T., Saito, D., Nakamura, M., Ohkawa, Y., Oda, Y., Suyama, M., Ito, T. & Ogawa, Y., 7 2019, : : Cancer Medicine. 8, 8, p. 3748-3760 13 p.

研究成果: ジャーナルへの寄稿記事

公開
Matrix Metalloproteinase 7
Neuroendocrine Tumors
Recurrence
Genes
Neoplasms
公開
Supercritical Fluid Chromatography
supercritical fluids
liquid chromatography
High performance liquid chromatography
chromatography

Comparison of sequential derivatization with concurrent methods for GC/MS-based metabolomics

Miyagawa, H. & Bamba, T., 2 2019, : : Journal of Bioscience and Bioengineering. 127, 2, p. 160-168 9 p.

研究成果: ジャーナルへの寄稿記事

Metabolomics
Metabolites
Gas chromatography
Gas Chromatography-Mass Spectrometry
Mass spectrometry

DegSampler3: Pairwise dependency model in degradation motif site prediction of substrate protein sequences

Maruyama, O. & Matsuzaki, F., 10 2019, Proceedings - 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering, BIBE 2019. Institute of Electrical and Electronics Engineers Inc., p. 11-17 7 p. 8941973. (Proceedings - 2019 IEEE 19th International Conference on Bioinformatics and Bioengineering, BIBE 2019).

研究成果: 著書/レポートタイプへの貢献会議での発言

Ubiquitin-Protein Ligases
Binding sites
Proteins
Degradation
Substrates